This is a Validated Antibody Database (VAD) review about cow synaptotagmin I, based on 7 published articles (read how Labome selects the articles), using synaptotagmin I antibody in all methods. It is aimed to help Labome visitors find the most suited synaptotagmin I antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
synaptotagmin I synonym: synaptotagmin-1; p65; synaptotagmin I; sytI

Invitrogen
mouse monoclonal (ASV30)
  • immunoprecipitation; mouse; fig 4b
  • western blot; mouse; fig 3b
In order to study the activity-driven interaction between presenilin 1 and synaptotagmin 1 and links to calcium, amyloid beta, and synapse, Invitrogen synaptotagmin I antibody (Pierce, MA125568) was used in immunoprecipitation on mouse samples (fig 4b) and in western blot on mouse samples (fig 3b). BMC Biol (2016) ncbi
mouse monoclonal (ASV30)
  • immunocytochemistry; rat; fig 3
  • western blot; hamsters; 1:1000; fig 2
In order to assess the interaction of APP with synaptotagmins that promotes A-beta generation, Invitrogen synaptotagmin I antibody (Thermo Fisher, ASV30) was used in immunocytochemistry on rat samples (fig 3) and in western blot on hamsters samples at 1:1000 (fig 2). Mol Neurodegener (2015) ncbi
EMD Millipore
mouse monoclonal
  • immunocytochemistry; mouse; 1:500; loading ...; fig 3a
EMD Millipore synaptotagmin I antibody (EMD Millipore, MAB5200) was used in immunocytochemistry on mouse samples at 1:500 (fig 3a). Sci Rep (2017) ncbi
mouse monoclonal
  • immunocytochemistry; mouse; 1:100; fig 8c
EMD Millipore synaptotagmin I antibody (Millipore, MAB5200) was used in immunocytochemistry on mouse samples at 1:100 (fig 8c). J Mol Neurosci (2017) ncbi
mouse monoclonal
  • immunoprecipitation; mouse; fig 3
  • western blot; mouse; fig 3
EMD Millipore synaptotagmin I antibody (Millipore, MAB5200) was used in immunoprecipitation on mouse samples (fig 3) and in western blot on mouse samples (fig 3). J Biol Chem (2016) ncbi
mouse monoclonal
  • western blot; rat; 1:1000; fig 9
EMD Millipore synaptotagmin I antibody (Millipore, MAB5200) was used in western blot on rat samples at 1:1000 (fig 9). Int J Neuropsychopharmacol (2015) ncbi
Sigma-Aldrich
rabbit polyclonal
  • immunohistochemistry - frozen section; mouse; fig 2c
  • western blot; mouse; fig 2d
In order to elucidate VAMP8- and VAMP2-mediated zymogen granules exocytosis, Sigma-Aldrich synaptotagmin I antibody (Sigma, s2177) was used in immunohistochemistry - frozen section on mouse samples (fig 2c) and in western blot on mouse samples (fig 2d). J Biol Chem (2014) ncbi
Articles Reviewed
  1. Getz A, Xu F, Visser F, Persson R, Syed N. Tumor suppressor menin is required for subunit-specific nAChR α5 transcription and nAChR-dependent presynaptic facilitation in cultured mouse hippocampal neurons. Sci Rep. 2017;7:1768 pubmed publisher
  2. Perland E, Hellsten S, Lekholm E, Eriksson M, Arapi V, Fredriksson R. The Novel Membrane-Bound Proteins MFSD1 and MFSD3 are Putative SLC Transporters Affected by Altered Nutrient Intake. J Mol Neurosci. 2017;61:199-214 pubmed publisher
  3. Kuzuya A, Zoltowska K, Post K, Arimon M, Li X, Svirsky S, et al. Identification of the novel activity-driven interaction between synaptotagmin 1 and presenilin 1 links calcium, synapse, and amyloid beta. BMC Biol. 2016;14:25 pubmed publisher
  4. Liu C, Song X, Nisbet R, Götz J. Co-immunoprecipitation with Tau Isoform-specific Antibodies Reveals Distinct Protein Interactions and Highlights a Putative Role for 2N Tau in Disease. J Biol Chem. 2016;291:8173-88 pubmed publisher
  5. Zhou J, Liu Z, Yu J, Han X, Fan S, Shao W, et al. Quantitative Proteomic Analysis Reveals Molecular Adaptations in the Hippocampal Synaptic Active Zone of Chronic Mild Stress-Unsusceptible Rats. Int J Neuropsychopharmacol. 2015;19: pubmed publisher
  6. Gautam V, D Avanzo C, Berezovska O, Tanzi R, Kovacs D. Synaptotagmins interact with APP and promote Aβ generation. Mol Neurodegener. 2015;10:31 pubmed publisher
  7. Messenger S, Falkowski M, Thomas D, Jones E, Hong W, Gaisano H, et al. Vesicle associated membrane protein 8 (VAMP8)-mediated zymogen granule exocytosis is dependent on endosomal trafficking via the constitutive-like secretory pathway. J Biol Chem. 2014;289:28040-53 pubmed publisher