This is a Validated Antibody Database (VAD) review about cow UQCRC2, based on 14 published articles (read how Labome selects the articles), using UQCRC2 antibody in all methods. It is aimed to help Labome visitors find the most suited UQCRC2 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
UQCRC2 synonym: cytochrome b-c1 complex subunit 2, mitochondrial; complex III subunit 2; core protein II; ubiquinol-cytochrome c reductase core protein II; ubiquinol-cytochrome-c reductase complex core protein 2

Abcam
mouse monoclonal (13G12AF12BB11)
  • western blot; mouse; 1:2000; loading ...; fig 3d
Abcam UQCRC2 antibody (Abcam, ab14745) was used in western blot on mouse samples at 1:2000 (fig 3d). EMBO Mol Med (2019) ncbi
mouse monoclonal (13G12AF12BB11)
  • western blot; human; fig 2a
Abcam UQCRC2 antibody (abcam, ab14745) was used in western blot on human samples (fig 2a). Nucleic Acids Res (2018) ncbi
mouse monoclonal (13G12AF12BB11)
  • western blot; rat; 1:1000; loading ...; fig 7a
Abcam UQCRC2 antibody (Abcam, ab14745) was used in western blot on rat samples at 1:1000 (fig 7a). PLoS ONE (2017) ncbi
mouse monoclonal (13G12AF12BB11)
  • western blot; human; loading ...; fig 5a
In order to identify the interactomes of 2 human adenine nucleotide translocase isoforms, Abcam UQCRC2 antibody (Abcam, ab14745) was used in western blot on human samples (fig 5a). Mol Biol Cell (2017) ncbi
mouse monoclonal (13G12AF12BB11)
  • western blot; human; loading ...; tbl 2
Abcam UQCRC2 antibody (Abcam, Ab14745) was used in western blot on human samples (tbl 2). EMBO Rep (2017) ncbi
mouse monoclonal (13G12AF12BB11)
  • western blot; human; 1:1000; loading ...; fig s3b
Abcam UQCRC2 antibody (Abcam, ab14745) was used in western blot on human samples at 1:1000 (fig s3b). Redox Biol (2017) ncbi
mouse monoclonal (13G12AF12BB11)
  • western blot; mouse; loading ...; fig 5c
In order to explore how caveolin-1 contributes to mitochondrial integrity and function, Abcam UQCRC2 antibody (abcam, ab14745) was used in western blot on mouse samples (fig 5c). Aging (Albany NY) (2016) ncbi
mouse monoclonal (13G12AF12BB11)
  • western blot; mouse; fig 1d
In order to identify a role for Ptcd3 in B-cell lymphoma, Abcam UQCRC2 antibody (Abcam, ab14745) was used in western blot on mouse samples (fig 1d). Oncotarget (2016) ncbi
mouse monoclonal (13G12AF12BB11)
  • western blot; human; loading ...; fig 1d
Abcam UQCRC2 antibody (Abcam, ab14745) was used in western blot on human samples (fig 1d). EMBO Mol Med (2016) ncbi
mouse monoclonal (13G12AF12BB11)
  • western blot; mouse; loading ...; fig s4d
In order to report cross-talk between mitochondrial elongation factor 4 -dependent quality control and cytoplasmic mechanistic (mammalian) target of rapamycin signaling, Abcam UQCRC2 antibody (Abcam, ab14745) was used in western blot on mouse samples (fig s4d). Nat Struct Mol Biol (2016) ncbi
mouse monoclonal (13G12AF12BB11)
  • western blot; mouse; loading ...; fig 1c
  • western blot; human; fig 1c
Abcam UQCRC2 antibody (Abcam, ab14745) was used in western blot on mouse samples (fig 1c) and in western blot on human samples (fig 1c). Hum Mol Genet (2016) ncbi
mouse monoclonal (13G12AF12BB11)
  • immunohistochemistry - paraffin section; human; loading ...; fig 1c
In order to study respiratory chain abnormalities and the contribution of mitochondrial DNA to the loss of respiratory chain complexes of idiopathic Parkinson disease patients at the single-neuron level, Abcam UQCRC2 antibody (Abcam, ab14745) was used in immunohistochemistry - paraffin section on human samples (fig 1c). Ann Neurol (2016) ncbi
mouse monoclonal (13G12AF12BB11)
  • western blot; mouse; 1:250; loading ...; fig 3d
Abcam UQCRC2 antibody (Abcam, ab14745) was used in western blot on mouse samples at 1:250 (fig 3d). Sci Rep (2015) ncbi
mouse monoclonal (13G12AF12BB11)
  • western blot; rat; 1:5000; loading ...; fig 4a
Abcam UQCRC2 antibody (Abcam, AB14745) was used in western blot on rat samples at 1:5000 (fig 4a). J Neurosci Res (2015) ncbi
Articles Reviewed
  1. Signes A, Cerutti R, Dickson A, Benincá C, Hinchy E, Ghezzi D, et al. APOPT1/COA8 assists COX assembly and is oppositely regulated by UPS and ROS. EMBO Mol Med. 2019;11: pubmed publisher
  2. Maiti P, Kim H, Tu Y, Barrientos A. Human GTPBP10 is required for mitoribosome maturation. Nucleic Acids Res. 2018;46:11423-11437 pubmed publisher
  3. Parajuli N, Shrum S, Tobacyk J, Harb A, Arthur J, Macmillan Crow L. Renal cold storage followed by transplantation impairs expression of key mitochondrial fission and fusion proteins. PLoS ONE. 2017;12:e0185542 pubmed publisher
  4. Lu Y, Acoba M, Selvaraju K, Huang T, Nirujogi R, Sathe G, et al. Human adenine nucleotide translocases physically and functionally interact with respirasomes. Mol Biol Cell. 2017;28:1489-1506 pubmed publisher
  5. Bourens M, Barrientos A. A CMC1-knockout reveals translation-independent control of human mitochondrial complex IV biogenesis. EMBO Rep. 2017;18:477-494 pubmed publisher
  6. Gomez Serrano M, Camafeita E, Lopez J, Rubio M, Bretón I, Garcia Consuegra I, et al. Differential proteomic and oxidative profiles unveil dysfunctional protein import to adipocyte mitochondria in obesity-associated aging and diabetes. Redox Biol. 2017;11:415-428 pubmed publisher
  7. Volonte D, Liu Z, Shiva S, Galbiati F. Caveolin-1 controls mitochondrial function through regulation of m-AAA mitochondrial protease. Aging (Albany NY). 2016;8:2355-2369 pubmed publisher
  8. D Andrea A, Gritti I, Nicoli P, Giorgio M, Doni M, Conti A, et al. The mitochondrial translation machinery as a therapeutic target in Myc-driven lymphomas. Oncotarget. 2016;7:72415-72430 pubmed publisher
  9. Janer A, Prudent J, Paupe V, Fahiminiya S, Majewski J, Sgarioto N, et al. SLC25A46 is required for mitochondrial lipid homeostasis and cristae maintenance and is responsible for Leigh syndrome. EMBO Mol Med. 2016;8:1019-38 pubmed publisher
  10. Gao Y, Bai X, Zhang D, Han C, Yuan J, Liu W, et al. Mammalian elongation factor 4 regulates mitochondrial translation essential for spermatogenesis. Nat Struct Mol Biol. 2016;23:441-9 pubmed publisher
  11. Lu Y, Galbraith L, Herndon J, Lü Y, Pras Raves M, Vervaart M, et al. Defining functional classes of Barth syndrome mutation in humans. Hum Mol Genet. 2016;25:1754-70 pubmed publisher
  12. Grünewald A, Rygiel K, Hepplewhite P, Morris C, Picard M, Turnbull D. Mitochondrial DNA Depletion in Respiratory Chain-Deficient Parkinson Disease Neurons. Ann Neurol. 2016;79:366-78 pubmed publisher
  13. Gouspillou G, Scheede Bergdahl C, Spendiff S, Vuda M, Meehan B, Mlynarski H, et al. Anthracycline-containing chemotherapy causes long-term impairment of mitochondrial respiration and increased reactive oxygen species release in skeletal muscle. Sci Rep. 2015;5:8717 pubmed publisher
  14. Jackson J, O Donnell J, Krizman E, Robinson M. Displacing hexokinase from mitochondrial voltage-dependent anion channel impairs GLT-1-mediated glutamate uptake but does not disrupt interactions between GLT-1 and mitochondrial proteins. J Neurosci Res. 2015;93:999-1008 pubmed publisher