This is a Validated Antibody Database (VAD) review about cow TEK, based on 6 published articles (read how Labome selects the articles), using TEK antibody in all methods. It is aimed to help Labome visitors find the most suited TEK antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
TEK synonym: angiopoietin-1 receptor; TEK tyrosine kinase, endothelial (venous malformations, multiple cutaneous and mucosal); endothelial tyrosine kinase; tie-2/tek receptor tyrosine kinase; tyrosine kinase with Ig and EGF homology domains-2; tyrosine-protein kinase receptor TIE-2

Abcam
rabbit polyclonal
  • western blot; human; loading ...; fig s1c
In order to study the role of distinct RNA transcriptome patterns in angiogenesis in Tie2-expressing monocytes, Abcam TEK antibody (Abcam, ab137786) was used in western blot on human samples (fig s1c). Gene (2016) ncbi
Cell Signaling Technology
mouse monoclonal (Ab33)
  • western blot; human; loading ...; fig s7b
Cell Signaling Technology TEK antibody (Cell Signaling, AB33) was used in western blot on human samples (fig s7b). Proc Natl Acad Sci U S A (2018) ncbi
mouse monoclonal (Ab33)
  • immunohistochemistry - paraffin section; human; fig 1I
Cell Signaling Technology TEK antibody (Cell Signaling, 4224) was used in immunohistochemistry - paraffin section on human samples (fig 1I). J Hematol Oncol (2017) ncbi
mouse monoclonal (Ab33)
  • immunohistochemistry - frozen section; human; 1:1000; loading ...; tbl 1
  • western blot; human; 1:1000; fig s4e
  • western blot; mouse; 1:1000; loading ...; fig 5i
In order to study the role of endothelial cell exocytosis in cerebral cavernous malformation disease progression, Cell Signaling Technology TEK antibody (Cell Signaling, 4224) was used in immunohistochemistry - frozen section on human samples at 1:1000 (tbl 1), in western blot on human samples at 1:1000 (fig s4e) and in western blot on mouse samples at 1:1000 (fig 5i). Nat Med (2016) ncbi
mouse monoclonal (Ab33)
  • western blot; human; fig s3e
Cell Signaling Technology TEK antibody (Cell Signaling, 4224) was used in western blot on human samples (fig s3e). Nucleic Acids Res (2016) ncbi
mouse monoclonal (Ab33)
  • western blot; human; fig 7
Cell Signaling Technology TEK antibody (Cell Signaling Technology, #4224) was used in western blot on human samples (fig 7). Am J Physiol Heart Circ Physiol (2015) ncbi
Articles Reviewed
  1. Souma T, Thomson B, Heinen S, Anna Carota I, Yamaguchi S, Onay T, et al. Context-dependent functions of angiopoietin 2 are determined by the endothelial phosphatase VEPTP. Proc Natl Acad Sci U S A. 2018;115:1298-1303 pubmed publisher
  2. Gravina G, Mancini A, Marampon F, Colapietro A, Delle Monache S, Sferra R, et al. The brain-penetrating CXCR4 antagonist, PRX177561, increases the antitumor effects of bevacizumab and sunitinib in preclinical models of human glioblastoma. J Hematol Oncol. 2017;10:5 pubmed publisher
  3. Jenny Zhou H, Qin L, Zhang H, Tang W, Ji W, He Y, et al. Endothelial exocytosis of angiopoietin-2 resulting from CCM3 deficiency contributes to cerebral cavernous malformation. Nat Med. 2016;22:1033-1042 pubmed publisher
  4. Warner M, Bridge K, Hewitson J, Hodgkinson M, Heyam A, Massa B, et al. S6K2-mediated regulation of TRBP as a determinant of miRNA expression in human primary lymphatic endothelial cells. Nucleic Acids Res. 2016;44:9942-9955 pubmed
  5. Wang X, Dai Z, Wu X, Wang K, Wang X. Distinct RNA transcriptome patterns are potentially associated with angiogenesis in Tie2-expressing monocytes. Gene. 2016;580:1-7 pubmed publisher
  6. Dokun A, Chen L, Okutsu M, Farber C, Hazarika S, Jones W, et al. ADAM12: a genetic modifier of preclinical peripheral arterial disease. Am J Physiol Heart Circ Physiol. 2015;309:H790-803 pubmed publisher