This is a Validated Antibody Database (VAD) review about cow RYR1, based on 46 published articles (read how Labome selects the articles), using RYR1 antibody in all methods. It is aimed to help Labome visitors find the most suited RYR1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
RYR1 synonym: ryanodine receptor 1; ryanodine receptor 1 (skeletal)
Knockout validation
Invitrogen mouse monoclonal (34C) |
| In order to assess the importance of RyanR type 3 in Alzheimer disease pathology, Invitrogen RYR1 antibody (Thermo, MA3?C925) was used in western blot knockout validation on mouse samples at 1:500 (fig s1b). Channels (Austin) (2014) ncbi |
Invitrogen
mouse monoclonal (34C) |
| Invitrogen RYR1 antibody (ThermoFisher, MA3-925) was used in western blot on mouse samples at 1:2000 (fig 2a). elife (2019) ncbi |
mouse monoclonal (34C) |
| In order to report the effects of short- and long-term high-fat diets on fast-twitch skeletal muscles, Invitrogen RYR1 antibody (Thermo Fisher Scientific, MA3-925) was used in western blot on mouse samples (fig 5a). Physiol Rep (2017) ncbi |
mouse monoclonal (34C) |
| In order to elucidate the mechanism by which the I4895T mutation in the type 1 ryanodine receptor/Ca(2+) release channel results in disease, Invitrogen RYR1 antibody (Thermo Scientific, MA3-925) was used in immunohistochemistry on mouse samples at 1:300 (fig 3c) and in western blot on mouse samples at 1:2000 (fig s2f). Nat Commun (2017) ncbi |
mouse monoclonal (34C) |
| In order to determine the role of calcium regulation in sporadic inclusion body myositis, Invitrogen RYR1 antibody (Thermo Fischer, MA3-925) was used in western blot on human samples at 1:500 (fig 1b). Acta Neuropathol Commun (2017) ncbi |
mouse monoclonal (34C) |
| In order to report the physiological role of sarcolipin upregulation in muscle myopathy, Invitrogen RYR1 antibody (Pierce Antibodies, MA3-925) was used in western blot on mouse samples (fig 2d). PLoS ONE (2017) ncbi |
mouse monoclonal (34C) |
| In order to assess the role of redox stress in PH-induced diaphragm weakness, Invitrogen RYR1 antibody (Thermo, MA3-925) was used in western blot on rat samples (fig 2e). PLoS ONE (2017) ncbi |
mouse monoclonal (34C) |
| In order to report the effects of eccentric contraction on calpain-dependent proteolysis of calcium ion-regulatory proteins and force production in fast-twitch skeletal muscles, Invitrogen RYR1 antibody (ThermoFisher Scientific, MA-925) was used in western blot on rat samples at 1:2500 (fig 4a). J Appl Physiol (1985) (2017) ncbi |
mouse monoclonal (34C) |
| In order to examine the effects of sildenafil on skeletal muscle, Invitrogen RYR1 antibody (Thermo Scientific, MA3-925) was used in western blot on mouse samples at 1:1000 (fig 5a). Exp Mol Med (2016) ncbi |
mouse monoclonal (34C) |
| In order to study the ryanodine receptor inhibitory action of the calmodulin p.Phe142Leu mutation, Invitrogen RYR1 antibody (Pierce, MA3-925) was used in western blot on human samples (fig 8a). J Biol Chem (2017) ncbi |
mouse monoclonal (34C) |
| In order to test if calcium dysregulation contributes to muscle dysfunction in patients with chronic obstructive pulmonary disease, Invitrogen RYR1 antibody (Thermo Fisher, MA3-925) was used in western blot on mouse samples (fig 4a). Muscle Nerve (2017) ncbi |
mouse monoclonal (34C) |
| In order to investigate the role of the S6 cytoplasmic region in the function of cardiac ryanodine receptor, Invitrogen RYR1 antibody (Thermo Fisher, MA3-925) was used in western blot on human samples at 1:1000 (fig 4a). J Biol Chem (2016) ncbi |
mouse monoclonal (34C) |
| In order to clarify the role of ryanodine receptor mutation in channel function, Invitrogen RYR1 antibody (Thermo Scientific, MA3-925) was used in western blot on mouse samples at 1:1000 (fig s2). J Biol Chem (2016) ncbi |
mouse monoclonal (34C) |
| In order to examine the effects of marijuana on CB1R activation in skeletal muscle, Invitrogen RYR1 antibody (Thermo Fisher, MA3-925) was used in immunohistochemistry on mouse samples at 1:500 (fig 1a) and in western blot on mouse samples at 1:1000. J Physiol (2016) ncbi |
mouse monoclonal (34C) |
| In order to test if neuromodulatory G-protein coupled receptors use beta-arrestin-dependent signaling to modulate neuronal excitability, Invitrogen RYR1 antibody (Pierce, MA3-925) was used in immunohistochemistry on mouse samples at 1:100 (fig 2c). Cell Rep (2016) ncbi |
mouse monoclonal (34C) |
| In order to elucidate how RYR1 mutations contributes to bleeding abnormalities, Invitrogen RYR1 antibody (Thermo Scientific, MA3-925) was used in immunocytochemistry on mouse samples (fig 2e). Sci Signal (2016) ncbi |
mouse monoclonal (34C) |
| In order to characterize calcium waves propagation in rat ventricular myocytes by the role of SERCA and the sarcoplasmic reticulum calcium content, Invitrogen RYR1 antibody (Thermo Fisher, MA3-925) was used in western blot on mouse samples at 1:2000 (fig 1). Arch Biochem Biophys (2016) ncbi |
mouse monoclonal (34C) |
| In order to study protection against acute myocardial infaction via hearts lacking Mfn1 and Mfn2, Invitrogen RYR1 antibody (Thermo, MA3-925) was used in proximity ligation assay on mouse samples at 1:500 (fig 4). Cell Death Dis (2016) ncbi |
mouse monoclonal (34C) |
| In order to analyze slow twitch skeletal muscles and the role of the JP45-calsequestrin complex on calcium entry, Invitrogen RYR1 antibody (Thermo Scientific, MA3-925) was used in western blot on mouse samples at 1:5000 (fig 2). J Biol Chem (2016) ncbi |
mouse monoclonal (34C) |
| In order to characterize modulation of ryanodine receptors during beta-adrenergic stimulation and restriction to the dyadic cleft via nictric oxide synthase-1 and calcium/calmodulin-dependent kinase II, Invitrogen RYR1 antibody (Thermo Scientific, MA3-925) was used in immunocytochemistry on pig samples at 1:200 (fig 6). J Physiol (2016) ncbi |
mouse monoclonal (34C) |
| In order to assess the function and characterization of extraocular muscles and obicularis oculi, Invitrogen RYR1 antibody (ThermoFisher Scientific, MA3-925) was used in immunocytochemistry on human samples (fig 4) and in western blot on human samples (fig 1). J Gen Physiol (2016) ncbi |
mouse monoclonal (34C) |
| In order to investigate the deficiency that affects SERCA expression and function in the skeletal muscle by Calpain 3, Invitrogen RYR1 antibody (Affinity BioReagents, MA3-925) was used in western blot on mouse samples (fig 1) and in western blot on human samples (fig 2). Expert Rev Mol Med (2016) ncbi |
mouse monoclonal (34C) |
| In order to characterize induction by doxorubicin causing early oxidative damage and the source of production, effect of Ca(2+) transporters in HL-1 cardiomyocytes and protection by GKT137831, Invitrogen RYR1 antibody (Pierce, MA3-925) was used in western blot on mouse samples (fig 2). Arch Biochem Biophys (2016) ncbi |
mouse monoclonal (34C) |
| In order to study the Ca(2+)-dependent protein-protein interactions within cardiac sarcoplasmic reticulum Ca(2+) release units, Invitrogen RYR1 antibody (ABR, MA3-925) was used in western blot on mouse samples (fig 1). Mol Cells (2016) ncbi |
mouse monoclonal (34C) |
| In order to investigate LRRC10 and its role in cardiac function under pressure, Invitrogen RYR1 antibody (Thermo Pierce, MA3-925) was used in immunohistochemistry - paraffin section on mouse samples at 1:200 (fig 6). Am J Physiol Heart Circ Physiol (2016) ncbi |
mouse monoclonal (34C) |
| In order to analyze Danio rerio for calsequestrins in cardiac and skeletal muscle, Invitrogen RYR1 antibody (Affinity Bioreagents, MA3-925) was used in immunohistochemistry - frozen section on zebrafish samples (fig 5). J Muscle Res Cell Motil (2016) ncbi |
mouse monoclonal (34C) |
| In order to investigate the impact of Tmem65 on heart development, Invitrogen RYR1 antibody (Life Technologies, 34C) was used in western blot on mouse samples at 1:2500. Nat Commun (2015) ncbi |
mouse monoclonal (34C) |
| In order to study SERCA dysfunction in mice overexpressing phospholamban, Invitrogen RYR1 antibody (Pierce Antibodies, MA3-925) was used in western blot on mouse samples and in western blot on human samples . Dis Model Mech (2015) ncbi |
mouse monoclonal (34C) |
| In order to determine the mechanisms that reduce ryanodine receptor 1 in patients with congenital myopathies, Invitrogen RYR1 antibody (Thermo Scientific, MA3-925) was used in western blot on mouse samples (fig 1). Hum Mol Genet (2015) ncbi |
mouse monoclonal (34C) |
| In order to determine which RYR1 variants contribute to malignant hyperthermia, Invitrogen RYR1 antibody (Thermo Scientific, MA3-925) was used in western blot on human samples . Neuromuscul Disord (2015) ncbi |
mouse monoclonal (34C) |
| In order to investigate Mitsugumin 56 in skeletal muscle maturation using knockout mice, Invitrogen RYR1 antibody (Thermo Scientific, MA3-925) was used in western blot on mouse samples . FEBS Lett (2015) ncbi |
mouse monoclonal (34C) |
| In order to study a missense mutation in the calsequestrin-1 gene discovered in a group of patients with a myopathy, Invitrogen RYR1 antibody (Thermo Scientific, 34C) was used in immunohistochemistry on mouse samples at 1 ug/ml. Hum Mutat (2014) ncbi |
mouse monoclonal (34C) |
| In order to study Kv2.1 expression and phosphorylation, Invitrogen RYR1 antibody (Pierce, MA3925) was used in immunohistochemistry - free floating section on mouse samples (fig 1). J Comp Neurol (2014) ncbi |
mouse monoclonal (34C) |
| In order to determine how nuclear calcium signaling controls nuclear BK channels that regulate gene expression, Invitrogen RYR1 antibody (Thermo, MA3-925) was used in western blot on mouse samples at 1:1000. Nat Neurosci (2014) ncbi |
mouse monoclonal (G-1) |
| In order to study the effect of regional t-tubule density during cardiomyocyte Ca(2+) homeostasis, Invitrogen RYR1 antibody (Thermo Scientific, MA1-83782) was used in immunocytochemistry on rat samples . Am J Physiol Heart Circ Physiol (2014) ncbi |
mouse monoclonal (34C) |
| In order to study the role of exagerated Ca(2+) signaling mediated by InsP3 receptor1 in the pathogenesis of mutant presenilin-linked Alzheimer's disease, Invitrogen RYR1 antibody (Affinity Bioreagents, MA3-925) was used in western blot on mouse samples at 1:2000. J Neurosci (2014) ncbi |
mouse monoclonal (34C) |
| In order to study Kv2.1 function and membrane excitability in the axon initial segment, Invitrogen RYR1 antibody (Pierce, MA3-925) was used in immunohistochemistry - free floating section on rat samples at 1 ug/ml. J Comp Neurol (2014) ncbi |
mouse monoclonal (34C) |
| In order to assess the importance of RyanR type 3 in Alzheimer disease pathology, Invitrogen RYR1 antibody (Thermo, MA3?C925) was used in western blot knockout validation on mouse samples at 1:500 (fig s1b). Channels (Austin) (2014) ncbi |
mouse monoclonal (34C) |
| In order to study the intracellular role of sorcin, Invitrogen RYR1 antibody (Antibody Directory, MA3-925) was used in immunocytochemistry on mouse samples . PLoS ONE (2014) ncbi |
mouse monoclonal (34C) |
| In order to study Ca(2+) handling in Purkinje cells, Invitrogen RYR1 antibody (Affinity BioReagents, MA3-925) was used in immunocytochemistry on pig samples at 1:200. J Physiol (2013) ncbi |
mouse monoclonal (34C) |
| In order to investigate a novel skeletal RYR1 mutation in an autosomal recessive heterogeneous congenital myopathy, Invitrogen RYR1 antibody (Thermo Scientific, MA3-925) was used in western blot on human samples (fig 2). PLoS ONE (2013) ncbi |
mouse monoclonal (34C) |
| In order to assess how deregulation of the protocadherin gene FAT1 changes muscle shape implying a role for the pathogenesis of facioscapulohumeral dystrophy, Invitrogen RYR1 antibody (Thermo scientific, MA3-925) was used in immunohistochemistry on mouse samples . PLoS Genet (2013) ncbi |
mouse monoclonal (34C) |
| In order to investigate the abnormalities of calcium handling proteins in skeletal and heart muscle during heart failure, Invitrogen RYR1 antibody (Pierce, 34C) was used in western blot on human samples . J Card Fail (2012) ncbi |
mouse monoclonal (34C) |
| In order to study calcium homeostasis and excitation-contraction coupling in cultured myotubes derived from two patients with Rippling muscle disease, Invitrogen RYR1 antibody (Thermo Scientific, MA3-925) was used in immunocytochemistry on human samples (fig 5) and in western blot on human samples (fig 1). Hum Mutat (2011) ncbi |
mouse monoclonal (34C) |
| Invitrogen RYR1 antibody (Affinity Bioreagents, MA3-925) was used in immunohistochemistry - frozen section on mouse samples at 1:800 and in immunocytochemistry on mouse samples at 1:800. J Comp Neurol (2008) ncbi |
mouse monoclonal (34C) |
| In order to suggest that S100A1 is an inhibitory modulator of RyR2 function at diastolic calcium concentrations in rabbit ventricular cardiomyocytes, Invitrogen RYR1 antibody (ABR, MA-3-925) was used in immunoprecipitation on rabbit samples (fig 5) and in western blot on rabbit samples (fig 5). Cell Calcium (2007) ncbi |
Sigma-Aldrich
mouse monoclonal (34C) |
| In order to study mechanisms by which chronic beta2-adrenergic stimulation enhances muscle force and power output during maximal cycle ergometer exercise in young men, Sigma-Aldrich RYR1 antibody (SigmaAldrich, R129) was used in western blot on human samples (fig 3f). J Appl Physiol (1985) (2015) ncbi |
Articles Reviewed
- Sun B, Guo W, Tian X, Yao J, Zhang L, Wang R, et al. The Cytoplasmic Region of Inner Helix S6 Is an Important Determinant of Cardiac Ryanodine Receptor Channel Gating. J Biol Chem. 2016;291:26024-26034 pubmed
- Xiao Z, Guo W, Sun B, Hunt D, Wei J, Liu Y, et al. Enhanced Cytosolic Ca2+ Activation Underlies a Common Defect of Central Domain Cardiac Ryanodine Receptor Mutations Linked to Arrhythmias. J Biol Chem. 2016;291:24528-24537 pubmed
- Liu J, Supnet C, Sun S, Zhang H, Good L, Popugaeva E, et al. The role of ryanodine receptor type 3 in a mouse model of Alzheimer disease. Channels (Austin). 2014;8:230-42 pubmed
- Völkers M, Loughrey C, Macquaide N, Remppis A, DeGeorge B, Wegner F, et al. S100A1 decreases calcium spark frequency and alters their spatial characteristics in permeabilized adult ventricular cardiomyocytes. Cell Calcium. 2007;41:135-43 pubmed
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