This is a Validated Antibody Database (VAD) review about cow PRG4, based on 5 published articles (read how Labome selects the articles), using PRG4 antibody in all methods. It is aimed to help Labome visitors find the most suited PRG4 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
PRG4 synonym: MSF; lubricin; proteoglycan 4; MLL septin-like fusion; proteoglycan 4, (megakaryocyte stimulating factor, articular superficial zone protein, camptodactyly, arthropathy, coxa vara, pericarditis syndrome)

Abcam
rabbit polyclonal
  • western blot; equine; loading ...; fig s1b
Abcam PRG4 antibody (Abcam, ab28484) was used in western blot on equine samples (fig s1b). Sci Rep (2016) ncbi
rabbit polyclonal
  • immunohistochemistry - paraffin section; rat; 1:100; fig 4
Abcam PRG4 antibody (Abcam, ab28484) was used in immunohistochemistry - paraffin section on rat samples at 1:100 (fig 4). Int J Mol Sci (2016) ncbi
rabbit polyclonal
  • immunocytochemistry; human
In order to investigate the effect of TNF and IL-10 on synovial fibroblasts, Abcam PRG4 antibody (Abcam, Ab28484) was used in immunocytochemistry on human samples . Cell Tissue Res (2014) ncbi
rabbit polyclonal
  • immunohistochemistry - paraffin section; mouse
In order to study the role of Notch signaling in murine articular cartilage and joint maintenance, Abcam PRG4 antibody (Abcam, ab28484) was used in immunohistochemistry - paraffin section on mouse samples . Arthritis Rheum (2013) ncbi
rabbit polyclonal
  • immunohistochemistry - paraffin section; mouse
Abcam PRG4 antibody (Abcam, ab 28484) was used in immunohistochemistry - paraffin section on mouse samples . Sci Transl Med (2013) ncbi
Articles Reviewed
  1. Reesink H, Bonnevie E, Liu S, Shurer C, Hollander M, Bonassar L, et al. Galectin-3 Binds to Lubricin and Reinforces the Lubricating Boundary Layer of Articular Cartilage. Sci Rep. 2016;6:25463 pubmed publisher
  2. Szychlinska M, Trovato F, Di Rosa M, Malaguarnera L, Puzzo L, Leonardi R, et al. Co-Expression and Co-Localization of Cartilage Glycoproteins CHI3L1 and Lubricin in Osteoarthritic Cartilage: Morphological, Immunohistochemical and Gene Expression Profiles. Int J Mol Sci. 2016;17:359 pubmed publisher
  3. Mrosewski I, Jork N, Gorte K, Conrad C, Wiegand E, Kohl B, et al. Regulation of osteoarthritis-associated key mediators by TNF? and IL-10: effects of IL-10 overexpression in human synovial fibroblasts and a synovial cell line. Cell Tissue Res. 2014;357:207-23 pubmed publisher
  4. Mirando A, Liu Z, Moore T, Lang A, Kohn A, Osinski A, et al. RBP-J?-dependent Notch signaling is required for murine articular cartilage and joint maintenance. Arthritis Rheum. 2013;65:2623-33 pubmed publisher
  5. Ruan M, Erez A, Guse K, Dawson B, Bertin T, Chen Y, et al. Proteoglycan 4 expression protects against the development of osteoarthritis. Sci Transl Med. 2013;5:176ra34 pubmed publisher