This is a Validated Antibody Database (VAD) review about cow PIK3CA, based on 52 published articles (read how Labome selects the articles), using PIK3CA antibody in all methods. It is aimed to help Labome visitors find the most suited PIK3CA antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
PIK3CA synonym: phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform; PI3-kinase p110 subunit alpha; PI3-kinase subunit alpha; PI3K; PI3K-alpha; PI3Kalpha; p110alpha; phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha; phosphoinositide-3-kinase, catalytic, alpha polypeptide; ptdIns-3-kinase p110; ptdIns-3-kinase subunit alpha; ptdIns-3-kinase subunit p110-alpha; serine/threonine protein kinase PIK3CA

Knockout validation
Cell Signaling Technology
rabbit monoclonal (C73F8)
  • western blot knockout validation; human; loading ...; fig 4a
  • immunoprecipitation; human; loading ...; fig 1d
Cell Signaling Technology PIK3CA antibody (Cell Signaling Technology, 4249S) was used in western blot knockout validation on human samples (fig 4a) and in immunoprecipitation on human samples (fig 1d). mSphere (2017) ncbi
Cell Signaling Technology
rabbit monoclonal (C73F8)
  • western blot knockout validation; mouse; fig 1
In order to elucidate the compartmentalization of p110alpha and p110beta, Cell Signaling Technology PIK3CA antibody (Cell Signaling, 4249) was used in western blot knockout validation on mouse samples (fig 1). elife (2016) ncbi
Cell Signaling Technology
rabbit monoclonal (C73F8)
  • western blot knockout validation; mouse; 1:1000; fig s1
Cell Signaling Technology PIK3CA antibody (Cell Signaling Tech, 4249) was used in western blot knockout validation on mouse samples at 1:1000 (fig s1). Nat Commun (2015) ncbi
Cell Signaling Technology
rabbit polyclonal
  • other; human; loading ...; fig 4c
Cell Signaling Technology PIK3CA antibody (Cell Signaling, 4255) was used in other on human samples (fig 4c). Cancer Cell (2018) ncbi
rabbit monoclonal (C73F8)
  • western blot; human; loading ...; fig 7a
Cell Signaling Technology PIK3CA antibody (Cell Signaling, 4249) was used in western blot on human samples (fig 7a). Biochim Biophys Acta Mol Basis Dis (2018) ncbi
rabbit monoclonal (C73F8)
  • western blot; mouse; 1:1000; loading ...; fig 3c
Cell Signaling Technology PIK3CA antibody (cell signaling, 4249) was used in western blot on mouse samples at 1:1000 (fig 3c). Oncogene (2017) ncbi
rabbit monoclonal (C73F8)
  • western blot knockout validation; human; loading ...; fig 4a
  • immunoprecipitation; human; loading ...; fig 1d
Cell Signaling Technology PIK3CA antibody (Cell Signaling Technology, 4249S) was used in western blot knockout validation on human samples (fig 4a) and in immunoprecipitation on human samples (fig 1d). mSphere (2017) ncbi
rabbit monoclonal (C73F8)
  • western blot; human; fig 1b
Cell Signaling Technology PIK3CA antibody (Cell Signaling, 4249) was used in western blot on human samples (fig 1b). Proc Natl Acad Sci U S A (2017) ncbi
rabbit monoclonal (C73F8)
  • western blot; mouse; loading ...; fig 4a
Cell Signaling Technology PIK3CA antibody (Cell Signaling Technology, 4249) was used in western blot on mouse samples (fig 4a). elife (2017) ncbi
rabbit monoclonal (C73F8)
  • western blot; human; fig 6a
Cell Signaling Technology PIK3CA antibody (Cell signaling, 4249) was used in western blot on human samples (fig 6a). Cancer Med (2017) ncbi
rabbit polyclonal
  • reverse phase protein lysate microarray; human; loading ...; fig st6
In order to characterize the molecular identity of uterine carcinosarcomas., Cell Signaling Technology PIK3CA antibody (CST, 4255) was used in reverse phase protein lysate microarray on human samples (fig st6). Cancer Cell (2017) ncbi
rabbit monoclonal (C73F8)
  • immunoprecipitation; human; 1:1000; loading ...; fig 4d
  • western blot; human; 1:1000; loading ...; fig 4d
Cell Signaling Technology PIK3CA antibody (Cell Signaling Technology, 4249) was used in immunoprecipitation on human samples at 1:1000 (fig 4d) and in western blot on human samples at 1:1000 (fig 4d). Oncotarget (2017) ncbi
rabbit monoclonal (C73F8)
  • western blot; human; 1:1000; loading ...; fig 2b
Cell Signaling Technology PIK3CA antibody (Cell Signaling, 4249) was used in western blot on human samples at 1:1000 (fig 2b). Nat Commun (2017) ncbi
rabbit monoclonal (C73F8)
  • western blot; human; 1:1000; loading ...; fig 6c
Cell Signaling Technology PIK3CA antibody (Cell Signaling, C73FB) was used in western blot on human samples at 1:1000 (fig 6c). Nat Commun (2016) ncbi
rabbit monoclonal (C73F8)
  • western blot; mouse; 1:1000; loading ...; fig s9a
In order to discuss how NLRC3 protects against colorectal cancer by modulating mTor signaling, Cell Signaling Technology PIK3CA antibody (Cell Signaling, 4249) was used in western blot on mouse samples at 1:1000 (fig s9a). Nature (2016) ncbi
rabbit polyclonal
  • western blot; human; fig 5b
In order to study the effect of PIK3CA in breast cancer., Cell Signaling Technology PIK3CA antibody (Cell Signaling, 4255S) was used in western blot on human samples (fig 5b). PLoS ONE (2016) ncbi
rabbit monoclonal (C73F8)
  • western blot; human; loading ...; fig 5a
Cell Signaling Technology PIK3CA antibody (Cell Signaling, 4249) was used in western blot on human samples (fig 5a). Sci Rep (2016) ncbi
rabbit monoclonal (C73F8)
  • western blot; mouse; loading ...; fig 1c
In order to determine if PIK3CA mutations contribute to tumor initiation, Cell Signaling Technology PIK3CA antibody (Cell Signaling, 4249) was used in western blot on mouse samples (fig 1c). Oncogenesis (2016) ncbi
rabbit monoclonal (C73F8)
  • western blot; human; loading ...; fig 6a
Cell Signaling Technology PIK3CA antibody (cell signalling, 4249) was used in western blot on human samples (fig 6a). PLoS ONE (2016) ncbi
rabbit monoclonal (C73F8)
  • western blot knockout validation; mouse; fig 1
In order to elucidate the compartmentalization of p110alpha and p110beta, Cell Signaling Technology PIK3CA antibody (Cell Signaling, 4249) was used in western blot knockout validation on mouse samples (fig 1). elife (2016) ncbi
rabbit monoclonal (C73F8)
  • western blot; human; fig s1
Cell Signaling Technology PIK3CA antibody (Cell Signaling, 4249) was used in western blot on human samples (fig s1). Cell Discov (2016) ncbi
rabbit monoclonal (C73F8)
  • western blot; human; loading ...; fig 5A
Cell Signaling Technology PIK3CA antibody (Cell signaling, C73F8) was used in western blot on human samples (fig 5A). Oncotarget (2016) ncbi
rabbit monoclonal (C73F8)
  • immunocytochemistry; human; loading ...; fig 4c,4d
  • western blot; human; 1:1000; loading ...; fig 5,6
  • immunohistochemistry - paraffin section; mouse; 1:100; loading ...; fig 7e
Cell Signaling Technology PIK3CA antibody (CST, 4249) was used in immunocytochemistry on human samples (fig 4c,4d), in western blot on human samples at 1:1000 (fig 5,6) and in immunohistochemistry - paraffin section on mouse samples at 1:100 (fig 7e). Oncotarget (2016) ncbi
rabbit monoclonal (C73F8)
  • western blot; mouse; fig 5
Cell Signaling Technology PIK3CA antibody (Cell Signaling Tech, 4249) was used in western blot on mouse samples (fig 5). Mol Syst Biol (2016) ncbi
rabbit monoclonal (C73F8)
  • western blot; mouse; loading ...; fig 2a
In order to examine the role of topoisomerase II in mitotic clonal expansion and adipogenesis, Cell Signaling Technology PIK3CA antibody (Cell Signaling, 4249) was used in western blot on mouse samples (fig 2a). Cell Signal (2016) ncbi
rabbit monoclonal (C73F8)
  • western blot; human; loading ...; fig 4c
Cell Signaling Technology PIK3CA antibody (Cell Signaling, C73F8) was used in western blot on human samples (fig 4c). Oncotarget (2016) ncbi
rabbit monoclonal (C73F8)
  • western blot; mouse; fig 6
Cell Signaling Technology PIK3CA antibody (Cell Signaling, 4249) was used in western blot on mouse samples (fig 6). Oncotarget (2016) ncbi
rabbit monoclonal (C73F8)
  • western blot; human; loading ...; fig 6a
In order to study the pharmacologic inhibition of PI3K and MEK pathways in mixed cultures of human mononuclear cells., Cell Signaling Technology PIK3CA antibody (Cell Signaling, 4249) was used in western blot on human samples (fig 6a). Am J Transplant (2016) ncbi
rabbit monoclonal (C73F8)
  • western blot; human; loading ...; fig 4
In order to find tumor types sensitive to phosphoinositide 3-kinase pathway inhibitors, Cell Signaling Technology PIK3CA antibody (Cell Signaling, 4249) was used in western blot on human samples (fig 4). Oncotarget (2016) ncbi
rabbit polyclonal
  • western blot; mouse; fig 5
Cell Signaling Technology PIK3CA antibody (Cell Signaling, 4255) was used in western blot on mouse samples (fig 5). J Clin Invest (2016) ncbi
rabbit monoclonal (C73F8)
  • immunohistochemistry - paraffin section; human; fig 7
  • immunohistochemistry - paraffin section; mouse; fig 4
Cell Signaling Technology PIK3CA antibody (Cell signaling, 4249) was used in immunohistochemistry - paraffin section on human samples (fig 7) and in immunohistochemistry - paraffin section on mouse samples (fig 4). Oncogene (2016) ncbi
rabbit polyclonal
  • western blot; mouse; fig 6
Cell Signaling Technology PIK3CA antibody (Cell signaling, 4255) was used in western blot on mouse samples (fig 6). Oncogene (2016) ncbi
rabbit polyclonal
  • western blot; human; fig 1
Cell Signaling Technology PIK3CA antibody (Cell Signaling, 4255) was used in western blot on human samples (fig 1). Oncotarget (2016) ncbi
rabbit monoclonal (C73F8)
  • immunohistochemistry - paraffin section; mouse; 1:200; fig s5
Cell Signaling Technology PIK3CA antibody (Cell Signaling Technology, 4249) was used in immunohistochemistry - paraffin section on mouse samples at 1:200 (fig s5). Cancer Sci (2016) ncbi
rabbit monoclonal (C73F8)
  • immunocytochemistry; human; fig 3
  • western blot; human; fig 3
Cell Signaling Technology PIK3CA antibody (Cell Signalling, 4249) was used in immunocytochemistry on human samples (fig 3) and in western blot on human samples (fig 3). Oncoscience (2015) ncbi
rabbit monoclonal (C73F8)
  • western blot knockout validation; mouse; 1:1000; fig s1
Cell Signaling Technology PIK3CA antibody (Cell Signaling Tech, 4249) was used in western blot knockout validation on mouse samples at 1:1000 (fig s1). Nat Commun (2015) ncbi
rabbit monoclonal (C73F8)
  • western blot; human; fig 5
Cell Signaling Technology PIK3CA antibody (Cell signaling, 4249) was used in western blot on human samples (fig 5). Oncogene (2016) ncbi
rabbit monoclonal (C73F8)
  • western blot; mouse; fig 3
In order to examine the effect of reelin derivatives on macrophage cholesterol metabolism, Cell Signaling Technology PIK3CA antibody (Cell Signaling, 4249) was used in western blot on mouse samples (fig 3). PLoS ONE (2015) ncbi
rabbit monoclonal (C73F8)
  • western blot; rat; 1:1000; fig 3
Cell Signaling Technology PIK3CA antibody (Cell Signaling, 4249S) was used in western blot on rat samples at 1:1000 (fig 3). Exp Cell Res (2015) ncbi
rabbit monoclonal (C73F8)
  • western blot; mouse; fig 3
Cell Signaling Technology PIK3CA antibody (Cell Signaling, 4249) was used in western blot on mouse samples (fig 3). EMBO Mol Med (2015) ncbi
rabbit monoclonal (C73F8)
  • western blot; human; 1:1000; fig 3
Cell Signaling Technology PIK3CA antibody (Cell Signaling, 4249S) was used in western blot on human samples at 1:1000 (fig 3). Cell Death Dis (2015) ncbi
rabbit monoclonal (C73F8)
  • western blot; mouse; fig 5
Cell Signaling Technology PIK3CA antibody (Cell signaling, 4249) was used in western blot on mouse samples (fig 5). Oncotarget (2015) ncbi
rabbit monoclonal (C73F8)
  • western blot; rat; fig 4
Cell Signaling Technology PIK3CA antibody (Cell Signaling Technology, 4249S) was used in western blot on rat samples (fig 4). Cell Physiol Biochem (2015) ncbi
rabbit monoclonal (C73F8)
  • western blot; human; fig 3
Cell Signaling Technology PIK3CA antibody (CST, 4249s) was used in western blot on human samples (fig 3). Cancer Res (2015) ncbi
rabbit monoclonal (C73F8)
  • western blot; human; fig 5
Cell Signaling Technology PIK3CA antibody (Cell Signaling Technology, 4249) was used in western blot on human samples (fig 5). Sci Rep (2015) ncbi
rabbit monoclonal (C73F8)
  • immunohistochemistry - paraffin section; human; 1:200; fig 1
Cell Signaling Technology PIK3CA antibody (Cell signaling, 4249) was used in immunohistochemistry - paraffin section on human samples at 1:200 (fig 1). Hum Pathol (2015) ncbi
rabbit monoclonal (C73F8)
  • western blot; human; fig 1
Cell Signaling Technology PIK3CA antibody (Cell Signaling, 4249) was used in western blot on human samples (fig 1). J Biol Chem (2015) ncbi
rabbit monoclonal (C73F8)
  • western blot; human; fig 5
Cell Signaling Technology PIK3CA antibody (Cell Signaling, 4249) was used in western blot on human samples (fig 5). Cell Death Dis (2015) ncbi
rabbit monoclonal (C73F8)
  • western blot; human; fig 1
Cell Signaling Technology PIK3CA antibody (Cell Signaling Technologies, 4249) was used in western blot on human samples (fig 1). Mol Cell (2014) ncbi
rabbit monoclonal (C73F8)
  • western blot; human; fig 4
Cell Signaling Technology PIK3CA antibody (Cell Signaling Technology, 4249) was used in western blot on human samples (fig 4). Oncol Rep (2015) ncbi
rabbit polyclonal
  • western blot; human
Cell Signaling Technology PIK3CA antibody (Cell Signalling Technology, 4255S) was used in western blot on human samples . Cell Prolif (2014) ncbi
rabbit monoclonal (C73F8)
  • western blot; mouse
  • western blot; human
Cell Signaling Technology PIK3CA antibody (Cell Signaling, C73F8) was used in western blot on mouse samples and in western blot on human samples . Mol Cell Biol (2014) ncbi
rabbit polyclonal
  • western blot; human; loading ...; fig 2a
Cell Signaling Technology PIK3CA antibody (Cell Signaling, 4255) was used in western blot on human samples (fig 2a). Sci Rep (2014) ncbi
rabbit monoclonal (C73F8)
  • western blot; rat; fig 1
Cell Signaling Technology PIK3CA antibody (Cell Signaling Technology, 4249S) was used in western blot on rat samples (fig 1). Pain (2014) ncbi
rabbit monoclonal (C73F8)
  • western blot; human
Cell Signaling Technology PIK3CA antibody (Cell Signalling, 4249) was used in western blot on human samples . J Cell Sci (2013) ncbi
rabbit monoclonal (C73F8)
  • western blot; human; 1:1000
Cell Signaling Technology PIK3CA antibody (Cell Signaling, 4249) was used in western blot on human samples at 1:1000. FEBS Lett (2013) ncbi
Articles Reviewed
  1. Ng P, Li J, Jeong K, Shao S, Chen H, Tsang Y, et al. Systematic Functional Annotation of Somatic Mutations in Cancer. Cancer Cell. 2018;33:450-462.e10 pubmed publisher
  2. Nan H, Han L, Ma J, Yang C, Su R, He J. STX3 represses the stability of the tumor suppressor PTEN to activate the PI3K-Akt-mTOR signaling and promotes the growth of breast cancer cells. Biochim Biophys Acta Mol Basis Dis. 2018;1864:1684-1692 pubmed publisher
  3. Simond A, Rao T, Zuo D, Zhao J, Muller W. ErbB2-positive mammary tumors can escape PI3K-p110α loss through downregulation of the Pten tumor suppressor. Oncogene. 2017;36:6059-6066 pubmed publisher
  4. Carpenter V, Chen Y, Dolat L, Valdivia R. The Effector TepP Mediates Recruitment and Activation of Phosphoinositide 3-Kinase on Early Chlamydia trachomatis Vacuoles. mSphere. 2017;2: pubmed publisher
  5. Hu L, Liang S, Chen H, Lv T, Wu J, Chen D, et al. ΔNp63α is a common inhibitory target in oncogenic PI3K/Ras/Her2-induced cell motility and tumor metastasis. Proc Natl Acad Sci U S A. 2017;114:E3964-E3973 pubmed publisher
  6. Zhang X, Spiegelman N, Nelson O, Jing H, Lin H. SIRT6 regulates Ras-related protein R-Ras2 by lysine defatty-acylation. elife. 2017;6: pubmed publisher
  7. Liu S, Gao G, Yan D, Chen X, Yao X, Guo S, et al. Effects of miR-145-5p through NRAS on the cell proliferation, apoptosis, migration, and invasion in melanoma by inhibiting MAPK and PI3K/AKT pathways. Cancer Med. 2017;6:819-833 pubmed publisher
  8. Cherniack A, Shen H, Walter V, Stewart C, Murray B, Bowlby R, et al. Integrated Molecular Characterization of Uterine Carcinosarcoma. Cancer Cell. 2017;31:411-423 pubmed publisher
  9. Dong Q, Fu L, Zhao Y, Tan S, Wang E. Derlin-1 overexpression confers poor prognosis in muscle invasive bladder cancer and contributes to chemoresistance and invasion through PI3K/AKT and ERK/MMP signaling. Oncotarget. 2017;8:17059-17069 pubmed publisher
  10. Kang Y, Balter B, Csizmadia E, Haas B, Sharma H, Bronson R, et al. Contribution of classical end-joining to PTEN inactivation in p53-mediated glioblastoma formation and drug-resistant survival. Nat Commun. 2017;8:14013 pubmed publisher
  11. Yang J, Savvatis K, Kang J, Fan P, Zhong H, Schwartz K, et al. Targeting LOXL2 for cardiac interstitial fibrosis and heart failure treatment. Nat Commun. 2016;7:13710 pubmed publisher
  12. Karki R, Man S, Malireddi R, Kesavardhana S, Zhu Q, Burton A, et al. NLRC3 is an inhibitory sensor of PI3K-mTOR pathways in cancer. Nature. 2016;: pubmed publisher
  13. Bhagirath D, Zhao X, Mirza S, West W, Band H, Band V. Mutant PIK3CA Induces EMT in a Cell Type Specific Manner. PLoS ONE. 2016;11:e0167064 pubmed publisher
  14. Sikander M, Hafeez B, Malik S, Alsayari A, Halaweish F, Yallapu M, et al. Cucurbitacin D exhibits potent anti-cancer activity in cervical cancer. Sci Rep. 2016;6:36594 pubmed publisher
  15. Sheen M, Marotti J, Allegrezza M, Rutkowski M, Conejo Garcia J, Fiering S. Constitutively activated PI3K accelerates tumor initiation and modifies histopathology of breast cancer. Oncogenesis. 2016;5:e267 pubmed publisher
  16. Visuttijai K, Pettersson J, Mehrbani Azar Y, van den Bout I, Orndal C, Marcickiewicz J, et al. Lowered Expression of Tumor Suppressor Candidate MYO1C Stimulates Cell Proliferation, Suppresses Cell Adhesion and Activates AKT. PLoS ONE. 2016;11:e0164063 pubmed publisher
  17. Cizmecioglu O, Ni J, Xie S, Zhao J, Roberts T. Rac1-mediated membrane raft localization of PI3K/p110? is required for its activation by GPCRs or PTEN loss. elife. 2016;5: pubmed publisher
  18. Yuzugullu H, Von T, Thorpe L, Walker S, Roberts T, Frank D, et al. NTRK2 activation cooperates with PTEN deficiency in T-ALL through activation of both the PI3K-AKT and JAK-STAT3 pathways. Cell Discov. 2016;2:16030 pubmed publisher
  19. Di Franco S, Turdo A, Benfante A, Colorito M, Gaggianesi M, Apuzzo T, et al. ?Np63 drives metastasis in breast cancer cells via PI3K/CD44v6 axis. Oncotarget. 2016;7:54157-54173 pubmed publisher
  20. Xi R, Pan S, Chen X, Hui B, Zhang L, Fu S, et al. HPV16 E6-E7 induces cancer stem-like cells phenotypes in esophageal squamous cell carcinoma through the activation of PI3K/Akt signaling pathway in vitro and in vivo. Oncotarget. 2016;7:57050-57065 pubmed publisher
  21. Voisinne G, García Blesa A, Chaoui K, Fiore F, Bergot E, Girard L, et al. Co-recruitment analysis of the CBL and CBLB signalosomes in primary T cells identifies CD5 as a key regulator of TCR-induced ubiquitylation. Mol Syst Biol. 2016;12:876 pubmed publisher
  22. Jacobsen R, Mazloumi Gavgani F, Mellgren G, Lewis A. DNA Topoisomerase II? contributes to the early steps of adipogenesis in 3T3-L1 cells. Cell Signal. 2016;28:1593-603 pubmed publisher
  23. Monica V, Lo Iacono M, Bracco E, Busso S, di Blasio L, Primo L, et al. Dasatinib modulates sensitivity to pemetrexed in malignant pleural mesothelioma cell lines. Oncotarget. 2016;7:76577-76589 pubmed publisher
  24. Qiu X, Wei R, Li Y, Zhu Q, Xiong C, Chen Y, et al. NEDL2 regulates enteric nervous system and kidney development in its Nedd8 ligase activity-dependent manner. Oncotarget. 2016;7:31440-53 pubmed publisher
  25. Zwang N, Zhang R, Germana S, Fan M, Hastings W, Cao A, et al. Selective Sparing of Human Tregs by Pharmacologic Inhibitors of the Phosphatidylinositol 3-Kinase and MEK Pathways. Am J Transplant. 2016;16:2624-38 pubmed publisher
  26. Lynch J, McEwen R, Crafter C, McDermott U, Garnett M, Barry S, et al. Identification of differential PI3K pathway target dependencies in T-cell acute lymphoblastic leukemia through a large cancer cell panel screen. Oncotarget. 2016;7:22128-39 pubmed publisher
  27. Winnay J, Solheim M, Dirice E, Sakaguchi M, Noh H, Kang H, et al. PI3-kinase mutation linked to insulin and growth factor resistance in vivo. J Clin Invest. 2016;126:1401-12 pubmed publisher
  28. Du L, Chen X, Cao Y, Lu L, Zhang F, Bornstein S, et al. Overexpression of PIK3CA in murine head and neck epithelium drives tumor invasion and metastasis through PDK1 and enhanced TGFβ signaling. Oncogene. 2016;35:4641-52 pubmed publisher
  29. Kulbe H, Iorio F, Chakravarty P, Milagre C, Moore R, Thompson R, et al. Integrated transcriptomic and proteomic analysis identifies protein kinase CK2 as a key signaling node in an inflammatory cytokine network in ovarian cancer cells. Oncotarget. 2016;7:15648-61 pubmed publisher
  30. Yamano S, Gi M, Tago Y, Doi K, Okada S, Hirayama Y, et al. Role of deltaNp63(pos)CD44v(pos) cells in the development of N-nitroso-tris-chloroethylurea-induced peripheral-type mouse lung squamous cell carcinomas. Cancer Sci. 2016;107:123-32 pubmed publisher
  31. Munkley J, Livermore K, McClurg U, Kalna G, Knight B, McCullagh P, et al. The PI3K regulatory subunit gene PIK3R1 is under direct control of androgens and repressed in prostate cancer cells. Oncoscience. 2015;2:755-64 pubmed
  32. Yuzugullu H, Baitsch L, Von T, Steiner A, Tong H, Ni J, et al. A PI3K p110β-Rac signalling loop mediates Pten-loss-induced perturbation of haematopoiesis and leukaemogenesis. Nat Commun. 2015;6:8501 pubmed publisher
  33. Kitatani K, Usui T, Sriraman S, Toyoshima M, Ishibashi M, Shigeta S, et al. Ceramide limits phosphatidylinositol-3-kinase C2β-controlled cell motility in ovarian cancer: potential of ceramide as a metastasis-suppressor lipid. Oncogene. 2016;35:2801-12 pubmed publisher
  34. Okoro E, Zhang H, Guo Z, Yang F, Smith C, Yang H. A Subregion of Reelin Suppresses Lipoprotein-Induced Cholesterol Accumulation in Macrophages. PLoS ONE. 2015;10:e0136895 pubmed publisher
  35. Geletu M, Guy S, Greer S, Raptis L. Differential effects of polyoma virus middle tumor antigen mutants upon gap junctional, intercellular communication. Exp Cell Res. 2015;336:223-31 pubmed publisher
  36. Stoy C, Sundaram A, Rios Garcia M, Wang X, Seibert O, Zota A, et al. Transcriptional co-factor Transducin beta-like (TBL) 1 acts as a checkpoint in pancreatic cancer malignancy. EMBO Mol Med. 2015;7:1048-62 pubmed publisher
  37. Cheng H, Liang Y, Kuo Y, Chuu C, Lin C, Lee M, et al. Identification of thioridazine, an antipsychotic drug, as an antiglioblastoma and anticancer stem cell agent using public gene expression data. Cell Death Dis. 2015;6:e1753 pubmed publisher
  38. Zhang W, Hou J, Wang X, Jiang R, Yin Y, Ji J, et al. PTPRO-mediated autophagy prevents hepatosteatosis and tumorigenesis. Oncotarget. 2015;6:9420-33 pubmed
  39. Zhang Z, Zhang T, Zhou Y, Wei X, Zhu J, Zhang J, et al. Activated phosphatidylinositol 3-kinase/Akt inhibits the transition of endothelial progenitor cells to mesenchymal cells by regulating the forkhead box subgroup O-3a signaling. Cell Physiol Biochem. 2015;35:1643-53 pubmed publisher
  40. Zhou Q, Derti A, Ruddy D, Rakiec D, Kao I, Lira M, et al. A chemical genetics approach for the functional assessment of novel cancer genes. Cancer Res. 2015;75:1949-58 pubmed publisher
  41. Lin Y, Yang Z, Xu A, Dong P, Huang Y, Liu H, et al. PIK3R1 negatively regulates the epithelial-mesenchymal transition and stem-like phenotype of renal cancer cells through the AKT/GSK3β/CTNNB1 signaling pathway. Sci Rep. 2015;5:8997 pubmed publisher
  42. You J, Yang H, Lai Y, Simon L, Au J, Burkart A. AT-rich interactive domain 2, p110α, p53, and β-catenin protein expression in hepatocellular carcinoma and clinicopathologic implications. Hum Pathol. 2015;46:583-92 pubmed publisher
  43. Aki S, Yoshioka K, Okamoto Y, Takuwa N, Takuwa Y. Phosphatidylinositol 3-kinase class II α-isoform PI3K-C2α is required for transforming growth factor β-induced Smad signaling in endothelial cells. J Biol Chem. 2015;290:6086-105 pubmed publisher
  44. Modelska A, Turro E, Russell R, Beaton J, Sbarrato T, Spriggs K, et al. The malignant phenotype in breast cancer is driven by eIF4A1-mediated changes in the translational landscape. Cell Death Dis. 2015;6:e1603 pubmed publisher
  45. Gasser J, Inuzuka H, Lau A, Wei W, Beroukhim R, Toker A. SGK3 mediates INPP4B-dependent PI3K signaling in breast cancer. Mol Cell. 2014;56:595-607 pubmed publisher
  46. Wang C, Zhang W, Fu M, Yang A, Huang H, Xie J. Establishment of human pancreatic cancer gemcitabine‑resistant cell line with ribonucleotide reductase overexpression. Oncol Rep. 2015;33:383-90 pubmed publisher
  47. Tang J, Shen L, Yang Q, Zhang C. Overexpression of metadherin mediates metastasis of osteosarcoma by regulating epithelial-mesenchymal transition. Cell Prolif. 2014;47:427-34 pubmed publisher
  48. Perez García V, Redondo Muñoz J, Kumar A, Carrera A. Cell activation-induced phosphoinositide 3-kinase alpha/beta dimerization regulates PTEN activity. Mol Cell Biol. 2014;34:3359-73 pubmed publisher
  49. Shaiken T, Opekun A. Dissecting the cell to nucleus, perinucleus and cytosol. Sci Rep. 2014;4:4923 pubmed publisher
  50. Leinders M, Koehrn F, Bartok B, Boyle D, Shubayev V, Kalcheva I, et al. Differential distribution of PI3K isoforms in spinal cord and dorsal root ganglia: potential roles in acute inflammatory pain. Pain. 2014;155:1150-60 pubmed publisher
  51. Barceló C, Paco N, Beckett A, Alvarez Moya B, Garrido E, Gelabert M, et al. Oncogenic K-ras segregates at spatially distinct plasma membrane signaling platforms according to its phosphorylation status. J Cell Sci. 2013;126:4553-9 pubmed publisher
  52. Kodigepalli K, Dutta P, Bauckman K, Nanjundan M. SnoN/SkiL expression is modulated via arsenic trioxide-induced activation of the PI3K/AKT pathway in ovarian cancer cells. FEBS Lett. 2013;587:5-16 pubmed publisher