This is a Validated Antibody Database (VAD) review about cow PARP1, based on 28 published articles (read how Labome selects the articles), using PARP1 antibody in all methods. It is aimed to help Labome visitors find the most suited PARP1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
PARP1 synonym: ADPRT; ARTD1; poly [ADP-ribose] polymerase 1; ADP-ribosyltransferase (NAD+) poly (ADP-ribose) polymerase); ADP-ribosyltransferase diphtheria toxin-like 1; ADPRT 1; NAD(+) ADP-ribosyltransferase 1; PARP-1; poly (ADP-ribose) polymerase family, member 1; poly(ADP-ribose) synthetase; poly[ADP-ribose] synthase 1; poly[ADP-ribose] synthetase 1

Enzo Life Sciences
rabbit polyclonal
  • western blot; human; loading ...; fig 1f
Enzo Life Sciences PARP1 antibody (Enzo, ALX-210-302) was used in western blot on human samples (fig 1f). MBio (2018) ncbi
mouse monoclonal (F1-23)
  • western blot; human; 1:1000; loading ...; fig 5a
Enzo Life Sciences PARP1 antibody (Alexis Biochemicals, ALX-804-211) was used in western blot on human samples at 1:1000 (fig 5a). Nucleic Acids Res (2018) ncbi
mouse monoclonal (C-2-10)
  • western blot; mouse; fig 2
Enzo Life Sciences PARP1 antibody (Enzo, BML-SA249) was used in western blot on mouse samples (fig 2). PLoS ONE (2016) ncbi
rabbit polyclonal
  • western blot; human; 1:2000; loading ...; fig 3b
Enzo Life Sciences PARP1 antibody (Enzo, BML-SA253) was used in western blot on human samples at 1:2000 (fig 3b). Oncotarget (2016) ncbi
rabbit polyclonal
  • western blot; human; 1:2000; loading ...; fig 3b
Enzo Life Sciences PARP1 antibody (Enzo, BML-SA253) was used in western blot on human samples at 1:2000 (fig 3b). Oncotarget (2016) ncbi
rabbit polyclonal
  • western blot; human; fig 6a
Enzo Life Sciences PARP1 antibody (Alexis, 210-302-R100) was used in western blot on human samples (fig 6a). PLoS Pathog (2016) ncbi
mouse monoclonal (C-2-10)
  • western blot; human; fig 3
Enzo Life Sciences PARP1 antibody (Enzo Life Sciences, C-2-10) was used in western blot on human samples (fig 3). Oncotarget (2016) ncbi
mouse monoclonal (C-2-10)
  • western blot; human; loading ...; fig 5b
Enzo Life Sciences PARP1 antibody (Enzo, C-2-10) was used in western blot on human samples (fig 5b). Cell Death Differ (2016) ncbi
mouse monoclonal (C-2-10)
  • western blot; human
In order to determine the action of PARP inhibition in different glioblastoma multiforme cell lines, Enzo Life Sciences PARP1 antibody (ALEXIS, C2-10) was used in western blot on human samples . Oncotarget (2015) ncbi
mouse monoclonal (C-2-10)
  • western blot; human; fig 3
In order to analyze ABT737 resistance in squamous cell carcinoma of the skin determined by the ratio of Mcl-1 and Noxa, Enzo Life Sciences PARP1 antibody (Biomol, C-2-10) was used in western blot on human samples (fig 3). Cell Death Dis (2014) ncbi
rabbit polyclonal
  • western blot; human; fig 4
In order to identify a novel anticancer mechanism that functions through autophagy-mediated necroptosis, Enzo Life Sciences PARP1 antibody (Enzo, ALX-210-302) was used in western blot on human samples (fig 4). Oncogene (2014) ncbi
rabbit polyclonal
  • western blot; human; 1:1000
Enzo Life Sciences PARP1 antibody (Alexis, ALX-210-220-R100) was used in western blot on human samples at 1:1000. J Cell Mol Med (2013) ncbi
rabbit polyclonal
  • EMSA; mouse
Enzo Life Sciences PARP1 antibody (Enzo Life Sciences, ALX-210-302-R100) was used in EMSA on mouse samples . J Biol Chem (2010) ncbi
mouse monoclonal (C-2-10)
  • western blot; human
In order to study the mechanism for enterovirulence of Escherichia coli strain C1845, Enzo Life Sciences PARP1 antibody (Enzo Life Sciences, C2-10) was used in western blot on human samples . Infect Immun (2010) ncbi
mouse monoclonal (C-2-10)
  • western blot; human
Enzo Life Sciences PARP1 antibody (Biomol, C-2-10) was used in western blot on human samples . J Neurooncol (2010) ncbi
mouse monoclonal (C-2-10)
  • western blot; human
Enzo Life Sciences PARP1 antibody (Alexis Biochemicals, C2-10) was used in western blot on human samples . J Biol Chem (2009) ncbi
mouse monoclonal (F1-23)
  • immunoprecipitation; human
Enzo Life Sciences PARP1 antibody (Alexis Biochemicals, F1-23) was used in immunoprecipitation on human samples . J Biol Chem (2009) ncbi
mouse monoclonal (C-2-10)
  • western blot; human
In order to examine the hepatotoxicity of TRAIL/bortezomib cotreatment, Enzo Life Sciences PARP1 antibody (Biomol, C-2-10) was used in western blot on human samples . Hepatology (2007) ncbi
mouse monoclonal (C-2-10)
  • western blot; Rhesus monkey
In order to study the activation of Bax during rotavirus-induced apoptosis, Enzo Life Sciences PARP1 antibody (Biomol, C-2-10) was used in western blot on Rhesus monkey samples . J Virol (2007) ncbi
Invitrogen
rabbit polyclonal
  • immunohistochemistry - paraffin section; rat; loading ...; fig 5c
In order to explore the use of bacterial carriers in a rat model of glioblastoma, Invitrogen PARP1 antibody (Thermo Fisher, 44-698G) was used in immunohistochemistry - paraffin section on rat samples (fig 5c). Mol Ther Oncolytics (2017) ncbi
mouse monoclonal (C-2-10)
  • immunohistochemistry - paraffin section; human; 1:1500
  • western blot; human; 1:1500
In order to study the involvement of decreased parkin solubility and reduced nigrostriatum autophagy in sporadic Parkinson's disease, Invitrogen PARP1 antibody (Pierce, MA3-950) was used in immunohistochemistry - paraffin section on human samples at 1:1500 and in western blot on human samples at 1:1500. Neuroscience (2013) ncbi
mouse monoclonal (C-2-10)
  • western blot; human
In order to investigate the interaction between HOXB7 and poly (ADP-ribose) polymerase-1, Invitrogen PARP1 antibody (Invitrogen, C-2-10) was used in western blot on human samples . PLoS ONE (2012) ncbi
rabbit polyclonal
  • western blot; human; fig 1
In order to elucidate resistance to MLN4924, Invitrogen PARP1 antibody (Invitrogen, 44698G) was used in western blot on human samples (fig 1). Cell Rep (2012) ncbi
rabbit polyclonal
  • western blot; human; fig 4
In order to study the regulation of the p38MAPK-p53-WIP1 pathway by BRCA1-IRIS in stressed and cancer cells, Invitrogen PARP1 antibody (Invitrogen, 44698G) was used in western blot on human samples (fig 4). Oncogene (2010) ncbi
rabbit polyclonal
  • western blot; human; fig 8
In order to investigate the function of the hydrophobic carboxy-terminal tail of Bax, Invitrogen PARP1 antibody (Invitrogen, 44698G) was used in western blot on human samples (fig 8). Apoptosis (2010) ncbi
mouse monoclonal (C-2-10)
  • western blot; human
In order to investigate the cellular localization and function of negative transcription elongation factor , Invitrogen PARP1 antibody (Affinity Bioreagents, MA3-950) was used in western blot on human samples . Exp Cell Res (2009) ncbi
mouse monoclonal (C-2-10)
  • western blot; mouse; 1:1000; fig 1A
In order to characterize defects in harlequin mutant mice, Invitrogen PARP1 antibody (Zymed, C-2-10) was used in western blot on mouse samples at 1:1000 (fig 1A). Cell Death Differ (2007) ncbi
mouse monoclonal (C-2-10)
  • western blot; human; fig 2
In order to identify pathways that are constitutively activated in a KIT-dependent manner in gastrointestinal stromal tumors, Invitrogen PARP1 antibody (Zymed, C-2-10) was used in western blot on human samples (fig 2). Oncogene (2004) ncbi
Abcam
rabbit polyclonal
  • western blot; human; 1:500; loading ...; fig 2b
In order to ask if the small-molecule inhibitor JQ1 in combination with romidepsin serves as a novel therapeutic option for type II testicular germ cell cancers, Abcam PARP1 antibody (Abcam, ab4830) was used in western blot on human samples at 1:500 (fig 2b). J Cell Mol Med (2017) ncbi
rabbit polyclonal
  • western blot; human
Abcam PARP1 antibody (Abcam, ab4830) was used in western blot on human samples . J Mol Signal (2013) ncbi
Articles Reviewed
  1. Sarracino A, Gharu L, Kula A, Pasternak A, Avettand Fenoel V, Rouzioux C, et al. Posttranscriptional Regulation of HIV-1 Gene Expression during Replication and Reactivation from Latency by Nuclear Matrix Protein MATR3. MBio. 2018;9: pubmed publisher
  2. Slyskova J, Sabatella M, Ribeiro Silva C, Stok C, Theil A, Vermeulen W, et al. Base and nucleotide excision repair facilitate resolution of platinum drugs-induced transcription blockage. Nucleic Acids Res. 2018;46:9537-9549 pubmed publisher
  3. Mehta N, Lyon J, Patil K, Mokarram N, Kim C, Bellamkonda R. Bacterial Carriers for Glioblastoma Therapy. Mol Ther Oncolytics. 2017;4:1-17 pubmed publisher
  4. Jostes S, Nettersheim D, Fellermeyer M, Schneider S, Hafezi F, Honecker F, et al. The bromodomain inhibitor JQ1 triggers growth arrest and apoptosis in testicular germ cell tumours in vitro and in vivo. J Cell Mol Med. 2017;21:1300-1314 pubmed publisher
  5. Hey F, Giblett S, Forrest S, Herbert C, Pritchard C. Phosphorylations of Serines 21/9 in Glycogen Synthase Kinase 3α/β Are Not Required for Cell Lineage Commitment or WNT Signaling in the Normal Mouse Intestine. PLoS ONE. 2016;11:e0156877 pubmed publisher
  6. Pesakhov S, Nachliely M, Barvish Z, Aqaqe N, Schwartzman B, Voronov E, et al. Cancer-selective cytotoxic Ca2+ overload in acute myeloid leukemia cells and attenuation of disease progression in mice by synergistically acting polyphenols curcumin and carnosic acid. Oncotarget. 2016;7:31847-61 pubmed publisher
  7. Lu F, Chen H, Kossenkov A, DeWispeleare K, Won K, Lieberman P. EBNA2 Drives Formation of New Chromosome Binding Sites and Target Genes for B-Cell Master Regulatory Transcription Factors RBP-jκ and EBF1. PLoS Pathog. 2016;12:e1005339 pubmed publisher
  8. Liberante F, Pouryahya T, McMullin M, Zhang S, Mills K. Identification and validation of the dopamine agonist bromocriptine as a novel therapy for high-risk myelodysplastic syndromes and secondary acute myeloid leukemia. Oncotarget. 2016;7:6609-19 pubmed publisher
  9. Charni M, Molchadsky A, Goldstein I, Solomon H, Tal P, Goldfinger N, et al. Novel p53 target genes secreted by the liver are involved in non-cell-autonomous regulation. Cell Death Differ. 2016;23:509-20 pubmed publisher
  10. Majuelos Melguizo J, Rodríguez M, López Jiménez L, Rodríguez Vargas J, Martí Martín Consuegra J, Serrano Sáenz S, et al. PARP targeting counteracts gliomagenesis through induction of mitotic catastrophe and aggravation of deficiency in homologous recombination in PTEN-mutant glioma. Oncotarget. 2015;6:4790-803 pubmed
  11. Geserick P, Wang J, Feoktistova M, Leverkus M. The ratio of Mcl-1 and Noxa determines ABT737 resistance in squamous cell carcinoma of the skin. Cell Death Dis. 2014;5:e1412 pubmed publisher
  12. Hedrick E, Agarwal E, Leiphrakpam P, Haferbier K, Brattain M, Chowdhury S. Differential PKA activation and AKAP association determines cell fate in cancer cells. J Mol Signal. 2013;8:10 pubmed publisher
  13. He W, Wang Q, Srinivasan B, Xu J, Padilla M, Li Z, et al. A JNK-mediated autophagy pathway that triggers c-IAP degradation and necroptosis for anticancer chemotherapy. Oncogene. 2014;33:3004-13 pubmed publisher
  14. Lonskaya I, Hebron M, Algarzae N, Desforges N, Moussa C. Decreased parkin solubility is associated with impairment of autophagy in the nigrostriatum of sporadic Parkinson's disease. Neuroscience. 2013;232:90-105 pubmed publisher
  15. Giansanti V, Rodriguez G, Savoldelli M, Gioia R, Forlino A, Mazzini G, et al. Characterization of stress response in human retinal epithelial cells. J Cell Mol Med. 2013;17:103-15 pubmed publisher
  16. Wu X, Ellmann S, Rubin E, Gil M, Jin K, Han L, et al. ADP ribosylation by PARP-1 suppresses HOXB7 transcriptional activity. PLoS ONE. 2012;7:e40644 pubmed publisher
  17. Toth J, Yang L, Dahl R, Petroski M. A gatekeeper residue for NEDD8-activating enzyme inhibition by MLN4924. Cell Rep. 2012;1:309-16 pubmed publisher
  18. Chen J, Sun Y, Mao X, Liu Q, Wu H, Chen Y. RANKL up-regulates brain-type creatine kinase via poly(ADP-ribose) polymerase-1 during osteoclastogenesis. J Biol Chem. 2010;285:36315-21 pubmed publisher
  19. Chock K, Allison J, ElShamy W. BRCA1-IRIS overexpression abrogates UV-induced p38MAPK/p53 and promotes proliferation of damaged cells. Oncogene. 2010;29:5274-85 pubmed publisher
  20. Sémiramoth N, Gleizes A, Turbica I, Sandré C, Marin Esteban V, Gorges R, et al. Afa/Dr-expressing, diffusely adhering Escherichia coli strain C1845 triggers F1845 fimbria-dependent phosphatidylserine externalization on neutrophil-like differentiated PLB-985 cells through an apoptosis-independent mechanism. Infect Immun. 2010;78:2974-83 pubmed publisher
  21. Brock S, Li C, Wattenberg B. The Bax carboxy-terminal hydrophobic helix does not determine organelle-specific targeting but is essential for maintaining Bax in an inactive state and for stable mitochondrial membrane insertion. Apoptosis. 2010;15:14-27 pubmed publisher
  22. Koschny R, Holland H, Sykora J, Erdal H, Krupp W, Bauer M, et al. Bortezomib sensitizes primary human esthesioneuroblastoma cells to TRAIL-induced apoptosis. J Neurooncol. 2010;97:171-85 pubmed publisher
  23. Rossi M, Carbone M, Mostocotto C, Mancone C, Tripodi M, Maione R, et al. Mitochondrial localization of PARP-1 requires interaction with mitofilin and is involved in the maintenance of mitochondrial DNA integrity. J Biol Chem. 2009;284:31616-24 pubmed publisher
  24. Yung T, Narita T, Komori T, Yamaguchi Y, Handa H. Cellular dynamics of the negative transcription elongation factor NELF. Exp Cell Res. 2009;315:1693-705 pubmed publisher
  25. Koschny R, Ganten T, Sykora J, Haas T, Sprick M, Kolb A, et al. TRAIL/bortezomib cotreatment is potentially hepatotoxic but induces cancer-specific apoptosis within a therapeutic window. Hepatology. 2007;45:649-58 pubmed
  26. Martin Latil S, Mousson L, Autret A, Colbere Garapin F, Blondel B. Bax is activated during rotavirus-induced apoptosis through the mitochondrial pathway. J Virol. 2007;81:4457-64 pubmed
  27. Zhu C, Wang X, Huang Z, Qiu L, Xu F, Vahsen N, et al. Apoptosis-inducing factor is a major contributor to neuronal loss induced by neonatal cerebral hypoxia-ischemia. Cell Death Differ. 2007;14:775-84 pubmed
  28. Duensing A, Medeiros F, McConarty B, Joseph N, Panigrahy D, Singer S, et al. Mechanisms of oncogenic KIT signal transduction in primary gastrointestinal stromal tumors (GISTs). Oncogene. 2004;23:3999-4006 pubmed