This is a Validated Antibody Database (VAD) review about cow NDUFA13, based on 5 published articles (read how Labome selects the articles), using NDUFA13 antibody in all methods. It is aimed to help Labome visitors find the most suited NDUFA13 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
NDUFA13 synonym: GRIM19; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13; CI-B16.6; GRIM-19; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13; NADH-ubiquinone oxidoreductase B16.6 subunit; cell death regulatory protein GRIM-19; cell death-regulatory protein GRIM19; complex I-B16.6; gene associated with retinoic-interferon-induced mortality 19 protein

Abcam
mouse monoclonal (6E1BH7)
  • immunohistochemistry; human; 1:100; fig 4
In order to use CLARITY to study mechanisms of neurodegeneration that occur in mitochondrial disease, Abcam NDUFA13 antibody (Abcam, ab110240) was used in immunohistochemistry on human samples at 1:100 (fig 4). Sci Rep (2016) ncbi
mouse monoclonal (6E1BH7)
  • immunohistochemistry - paraffin section; human; loading ...; fig 2e
In order to study respiratory chain abnormalities and the contribution of mitochondrial DNA to the loss of respiratory chain complexes of idiopathic Parkinson disease patients at the single-neuron level, Abcam NDUFA13 antibody (Abcam, ab110240) was used in immunohistochemistry - paraffin section on human samples (fig 2e). Ann Neurol (2016) ncbi
mouse monoclonal (6E1BH7)
  • immunohistochemistry - paraffin section; human; 1:100; loading ...; fig st2
In order to measure mitochondrial respiratory chain protein expression in Purkinje cell bodies and their synaptic terminals in the dentate nucleus, Abcam NDUFA13 antibody (Abcam, ab110240) was used in immunohistochemistry - paraffin section on human samples at 1:100 (fig st2). Neuropathol Appl Neurobiol (2016) ncbi
Invitrogen
mouse monoclonal (17D95)
  • western blot; mouse; 1:1000; fig 5
In order to find the function of transcriptional coregulator PGC-1beta in mitochondria and anti-oxidant defense in skeletal muscles, Invitrogen NDUFA13 antibody (Invitrogen, 439200) was used in western blot on mouse samples at 1:1000 (fig 5). Nat Commun (2015) ncbi
mouse monoclonal (17D95)
  • western blot; mouse; 1:4000
In order to assess the use of gene therapy in treating Friedreich's ataxia cardiomyopathy in a mouse model, Invitrogen NDUFA13 antibody (Invitrogen, 439200) was used in western blot on mouse samples at 1:4000. Nat Med (2014) ncbi
Articles Reviewed
  1. Phillips J, Laude A, Lightowlers R, Morris C, Turnbull D, Lax N. Development of passive CLARITY and immunofluorescent labelling of multiple proteins in human cerebellum: understanding mechanisms of neurodegeneration in mitochondrial disease. Sci Rep. 2016;6:26013 pubmed publisher
  2. Gali Ramamoorthy T, Laverny G, Schlagowski A, Zoll J, Messaddeq N, Bornert J, et al. The transcriptional coregulator PGC-1β controls mitochondrial function and anti-oxidant defence in skeletal muscles. Nat Commun. 2015;6:10210 pubmed publisher
  3. Grünewald A, Rygiel K, Hepplewhite P, Morris C, Picard M, Turnbull D. Mitochondrial DNA Depletion in Respiratory Chain-Deficient Parkinson Disease Neurons. Ann Neurol. 2016;79:366-78 pubmed publisher
  4. Chrysostomou A, Grady J, Laude A, Taylor R, Turnbull D, Lax N. Investigating complex I deficiency in Purkinje cells and synapses in patients with mitochondrial disease. Neuropathol Appl Neurobiol. 2016;42:477-92 pubmed publisher
  5. Perdomini M, Belbellaa B, Monassier L, Reutenauer L, Messaddeq N, Cartier N, et al. Prevention and reversal of severe mitochondrial cardiomyopathy by gene therapy in a mouse model of Friedreich's ataxia. Nat Med. 2014;20:542-7 pubmed publisher