This is a Validated Antibody Database (VAD) review about cow MAP3K14, based on 12 published articles (read how Labome selects the articles), using MAP3K14 antibody in all methods. It is aimed to help Labome visitors find the most suited MAP3K14 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
MAP3K14 synonym: mitogen-activated protein kinase kinase kinase 14

Knockout validation
Cell Signaling Technology
rabbit polyclonal
  • western blot knockout validation; mouse; fig s6i
Cell Signaling Technology MAP3K14 antibody (Cell Signaling, 4994) was used in western blot knockout validation on mouse samples (fig s6i). Cell (2018) ncbi
Cell Signaling Technology
rabbit polyclonal
  • western blot; human; 1:500; loading ...; fig s3c
  • western blot knockout validation; mouse; 1:500; fig s3d
Cell Signaling Technology MAP3K14 antibody (Cell Signaling, 4994P) was used in western blot on human samples at 1:500 (fig s3c) and in western blot knockout validation on mouse samples at 1:500 (fig s3d). Nat Cell Biol (2017) ncbi
Cell Signaling Technology
rabbit polyclonal
  • western blot knockout validation; human; fig 1
  • immunocytochemistry; mouse; fig 1
Cell Signaling Technology MAP3K14 antibody (cell Signaling Tech, CST4994) was used in western blot knockout validation on human samples (fig 1) and in immunocytochemistry on mouse samples (fig 1). Curr Biol (2016) ncbi
Cell Signaling Technology
rabbit polyclonal
  • western blot knockout validation; mouse; fig s8
  • western blot; human; fig 1
Cell Signaling Technology MAP3K14 antibody (Cell Signaling, 4994) was used in western blot knockout validation on mouse samples (fig s8) and in western blot on human samples (fig 1). Oncogenesis (2016) ncbi
Cell Signaling Technology
rabbit polyclonal
  • western blot knockout validation; mouse; fig s6i
Cell Signaling Technology MAP3K14 antibody (Cell Signaling, 4994) was used in western blot knockout validation on mouse samples (fig s6i). Cell (2018) ncbi
rabbit polyclonal
  • western blot; human; 1:500; loading ...; fig s3c
  • western blot knockout validation; mouse; 1:500; fig s3d
Cell Signaling Technology MAP3K14 antibody (Cell Signaling, 4994P) was used in western blot on human samples at 1:500 (fig s3c) and in western blot knockout validation on mouse samples at 1:500 (fig s3d). Nat Cell Biol (2017) ncbi
rabbit polyclonal
  • immunohistochemistry - frozen section; human; loading ...; fig 3d
In order to propose that NIK is a mediator of glucocorticoid-induced skeletal muscle atrophy, Cell Signaling Technology MAP3K14 antibody (Cell Signaling, 4994) was used in immunohistochemistry - frozen section on human samples (fig 3d). Physiol Rep (2016) ncbi
rabbit polyclonal
  • western blot knockout validation; human; fig 1
  • immunocytochemistry; mouse; fig 1
Cell Signaling Technology MAP3K14 antibody (cell Signaling Tech, CST4994) was used in western blot knockout validation on human samples (fig 1) and in immunocytochemistry on mouse samples (fig 1). Curr Biol (2016) ncbi
rabbit polyclonal
  • western blot; mouse; loading ...; fig 3d
Cell Signaling Technology MAP3K14 antibody (Cell Signaling, 4994) was used in western blot on mouse samples (fig 3d). Oncotarget (2016) ncbi
rabbit polyclonal
  • western blot knockout validation; mouse; fig s8
  • western blot; human; fig 1
Cell Signaling Technology MAP3K14 antibody (Cell Signaling, 4994) was used in western blot knockout validation on mouse samples (fig s8) and in western blot on human samples (fig 1). Oncogenesis (2016) ncbi
rabbit polyclonal
  • western blot; human; fig 2
Cell Signaling Technology MAP3K14 antibody (Cell Signaling Technology, 4994) was used in western blot on human samples (fig 2). Cell Death Dis (2016) ncbi
rabbit polyclonal
  • western blot; human; fig 6
Cell Signaling Technology MAP3K14 antibody (Cell Signaling, 4994) was used in western blot on human samples (fig 6). Sci Rep (2015) ncbi
rabbit polyclonal
  • western blot; mouse; fig s8
Cell Signaling Technology MAP3K14 antibody (CST, 4994P) was used in western blot on mouse samples (fig s8). Proc Natl Acad Sci U S A (2015) ncbi
rabbit polyclonal
  • western blot; human; 1:1000; fig 5
Cell Signaling Technology MAP3K14 antibody (Cells Signaling Technology, 4994) was used in western blot on human samples at 1:1000 (fig 5). Oncotarget (2014) ncbi
rabbit polyclonal
  • western blot; human; loading ...; fig 5d
Cell Signaling Technology MAP3K14 antibody (Cell Signaling, 4994) was used in western blot on human samples (fig 5d). PLoS ONE (2014) ncbi
rabbit polyclonal
  • western blot; human
Cell Signaling Technology MAP3K14 antibody (Cell Signaling, 4994) was used in western blot on human samples . PLoS ONE (2014) ncbi
Articles Reviewed
  1. Zhao P, Wong K, Sun X, Reilly S, Uhm M, Liao Z, et al. TBK1 at the Crossroads of Inflammation and Energy Homeostasis in Adipose Tissue. Cell. 2018;172:731-743.e12 pubmed publisher
  2. Giampazolias E, Zunino B, Dhayade S, Bock F, Cloix C, Cao K, et al. Mitochondrial permeabilization engages NF-κB-dependent anti-tumour activity under caspase deficiency. Nat Cell Biol. 2017;19:1116-1129 pubmed publisher
  3. Fry C, Nayeem S, Dillon E, Sarkar P, Tumurbaatar B, Urban R, et al. Glucocorticoids increase skeletal muscle NF-?B inducing kinase (NIK): links to muscle atrophy. Physiol Rep. 2016;4: pubmed
  4. Jung J, Ravi S, Lee D, McFadden K, Kamradt M, Toussaint L, et al. NIK/MAP3K14 Regulates Mitochondrial Dynamics and Trafficking to Promote Cell Invasion. Curr Biol. 2016;26:3288-3302 pubmed publisher
  5. Zhou Y, Xu H, Ding Y, Lu Q, Zou M, Song P. AMPK?1 deletion in fibroblasts promotes tumorigenesis in athymic nude mice by p52-mediated elevation of erythropoietin and CDK2. Oncotarget. 2016;7:53654-53667 pubmed publisher
  6. Duran C, Lee D, Jung J, Ravi S, Pogue C, Toussaint L, et al. NIK regulates MT1-MMP activity and promotes glioma cell invasion independently of the canonical NF-?B pathway. Oncogenesis. 2016;5:e231 pubmed publisher
  7. Schirmer M, Trentin L, Queudeville M, Seyfried F, Demir S, Tausch E, et al. Intrinsic and chemo-sensitizing activity of SMAC-mimetics on high-risk childhood acute lymphoblastic leukemia. Cell Death Dis. 2016;7:e2052 pubmed publisher
  8. Yamagishi M, Katano H, Hishima T, Shimoyama T, Ota Y, Nakano K, et al. Coordinated loss of microRNA group causes defenseless signaling in malignant lymphoma. Sci Rep. 2015;5:17868 pubmed publisher
  9. Lin D, Zhang M, Zhang M, Ren Y, Jin J, Zhao Q, et al. Induction of USP25 by viral infection promotes innate antiviral responses by mediating the stabilization of TRAF3 and TRAF6. Proc Natl Acad Sci U S A. 2015;112:11324-9 pubmed publisher
  10. Choi J, Park B, Chi S, Bae K, Kim S, Cho S, et al. HAX1 regulates E3 ubiquitin ligase activity of cIAPs by promoting their dimerization. Oncotarget. 2014;5:10084-99 pubmed
  11. Baens M, Bonsignore L, Somers R, Vanderheydt C, Weeks S, Gunnarsson J, et al. MALT1 auto-proteolysis is essential for NF-?B-dependent gene transcription in activated lymphocytes. PLoS ONE. 2014;9:e103774 pubmed publisher
  12. Uno M, Saitoh Y, Mochida K, Tsuruyama E, Kiyono T, Imoto I, et al. NF-?B inducing kinase, a central signaling component of the non-canonical pathway of NF-?B, contributes to ovarian cancer progression. PLoS ONE. 2014;9:e88347 pubmed publisher