This is a Validated Antibody Database (VAD) review about cow LOC525863, based on 28 published articles (read how Labome selects the articles), using LOC525863 antibody in all methods. It is aimed to help Labome visitors find the most suited LOC525863 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
LOC525863 synonym: histone H4

Invitrogen
mouse monoclonal (S.99.5)
  • western blot; human; 1:10,000; fig 2a
Invitrogen LOC525863 antibody (Thermo Fisher Scientific, MA5-14816) was used in western blot on human samples at 1:10,000 (fig 2a). Sci Rep (2017) ncbi
Cell Signaling Technology
mouse monoclonal (L64C1)
  • western blot; human; loading ...; fig 1c
In order to study the role of ACK1/TNK2 in histone H4 Tyr88-phosphorylation and androgen receptor expression in prostate cancer, Cell Signaling Technology LOC525863 antibody (Cell Signaling, 2935) was used in western blot on human samples (fig 1c). Cancer Cell (2017) ncbi
rabbit monoclonal (D12B3)
  • chromatin immunoprecipitation; rat; loading ...; fig 7c
In order to research the role of HDAC9 in regulating kidney angiotensinogen expression, Cell Signaling Technology LOC525863 antibody (Cell Signaling, 8647) was used in chromatin immunoprecipitation on rat samples (fig 7c). Biol Sex Differ (2017) ncbi
mouse monoclonal (L64C1)
  • western blot; mouse; loading ...; fig 5
Cell Signaling Technology LOC525863 antibody (cell signalling, L64C1) was used in western blot on mouse samples (fig 5). J Cell Sci (2017) ncbi
rabbit polyclonal
  • other; human; 1:100; loading ...; fig 3
Cell Signaling Technology LOC525863 antibody (Cell Signal, 9724) was used in other on human samples at 1:100 (fig 3). Nat Chem Biol (2017) ncbi
rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig 1d
In order to investigate the mechanism by which vorinostat suppresses matrix metallopeptidase-13, Cell Signaling Technology LOC525863 antibody (Cell Signaling, 9672) was used in western blot on human samples at 1:1000 (fig 1d). Am J Pathol (2016) ncbi
rabbit monoclonal (D84D2)
  • immunohistochemistry - paraffin section; human; fig 1
Cell Signaling Technology LOC525863 antibody (Cell Signaling, cs5737) was used in immunohistochemistry - paraffin section on human samples (fig 1). Genome Biol (2016) ncbi
mouse monoclonal (L64C1)
  • western blot; human; loading ...; fig 2b
In order to show that FLCN regulates mTORC1 by modulating the leucine signal in lysosome, Cell Signaling Technology LOC525863 antibody (Cell Signalling, 2935) was used in western blot on human samples (fig 2b). PLoS ONE (2016) ncbi
rabbit polyclonal
  • immunocytochemistry; mouse; 1:200
Cell Signaling Technology LOC525863 antibody (CST, 9724S) was used in immunocytochemistry on mouse samples at 1:200. Microsc Microanal (2015) ncbi
mouse monoclonal (L64C1)
  • western blot; rat
Cell Signaling Technology LOC525863 antibody (Cell Signaling, 2935) was used in western blot on rat samples . PLoS ONE (2015) ncbi
rabbit polyclonal
  • immunohistochemistry - paraffin section; mouse
Cell Signaling Technology LOC525863 antibody (Cell Signaling Technology, 9759S) was used in immunohistochemistry - paraffin section on mouse samples . J Reprod Dev (2014) ncbi
rabbit polyclonal
  • chromatin immunoprecipitation; human; fig 5
In order to study the oncogenic and developmental properties of TBX3, Cell Signaling Technology LOC525863 antibody (Cell Signaling, 9672) was used in chromatin immunoprecipitation on human samples (fig 5). elife (2014) ncbi
mouse monoclonal (L64C1)
  • western blot; human
Cell Signaling Technology LOC525863 antibody (Cell Signaling, 2935) was used in western blot on human samples . Eur Respir J (2014) ncbi
rabbit polyclonal
  • western blot; human
Cell Signaling Technology LOC525863 antibody (Cell Signaling, 9672) was used in western blot on human samples . J Biol Chem (2013) ncbi
EMD Millipore
rabbit polyclonal
  • western blot; mouse; loading ...; fig s3a
EMD Millipore LOC525863 antibody (Millipore, 07-108) was used in western blot on mouse samples (fig s3a). Science (2018) ncbi
rabbit polyclonal
  • western blot; human; 1:100; loading ...; fig 1d
EMD Millipore LOC525863 antibody (Millipore, 07-108) was used in western blot on human samples at 1:100 (fig 1d). Mol Cell Proteomics (2017) ncbi
rabbit polyclonal
  • western blot; human; loading ...; fig 5c
EMD Millipore LOC525863 antibody (Millipore, 07-108) was used in western blot on human samples (fig 5c). Exp Mol Med (2016) ncbi
rabbit polyclonal
  • chromatin immunoprecipitation; human; fig 5
  • western blot; human; fig 5
EMD Millipore LOC525863 antibody (Millipore, MM07-108) was used in chromatin immunoprecipitation on human samples (fig 5) and in western blot on human samples (fig 5). Nat Commun (2016) ncbi
rabbit polyclonal
  • western blot; human; 1:1000; fig 1
EMD Millipore LOC525863 antibody (Millipore, 07-108) was used in western blot on human samples at 1:1000 (fig 1). Mol Med Rep (2016) ncbi
rabbit polyclonal
  • western blot; mouse
EMD Millipore LOC525863 antibody (Millipore, 07-108) was used in western blot on mouse samples . Neurobiol Aging (2015) ncbi
rabbit polyclonal
  • western blot; human; 1:1000; fig 7
EMD Millipore LOC525863 antibody (Millipore, 07-108) was used in western blot on human samples at 1:1000 (fig 7). Cancer Biol Ther (2015) ncbi
rabbit polyclonal
  • western blot; human; 1:250; fig 6
EMD Millipore LOC525863 antibody (Millipore, 07-108) was used in western blot on human samples at 1:250 (fig 6). Nat Commun (2015) ncbi
rabbit polyclonal
  • chromatin immunoprecipitation; mouse; fig s7
EMD Millipore LOC525863 antibody (Upstate, 07-108) was used in chromatin immunoprecipitation on mouse samples (fig s7). Nat Commun (2015) ncbi
rabbit polyclonal
  • western blot; human; fig  8
In order to demonstrate that edimethylaminoparthenolide is an epigenetic modulator and acts in a NF-kappaB-dependent and -independent manner, EMD Millipore LOC525863 antibody (Upstate Biotechnology/Millipore, 07-108) was used in western blot on human samples (fig  8). Cell Death Dis (2015) ncbi
rabbit polyclonal
  • immunocytochemistry; human
EMD Millipore LOC525863 antibody (Millipore, 07-108) was used in immunocytochemistry on human samples . Int J Mol Sci (2014) ncbi
rabbit polyclonal
  • western blot; human
EMD Millipore LOC525863 antibody (Millipore, 07-108) was used in western blot on human samples . Mol Cell Biochem (2014) ncbi
rabbit polyclonal
  • western blot; mouse; 1:2000
EMD Millipore LOC525863 antibody (Millipore, 07-108) was used in western blot on mouse samples at 1:2000. J Biol Chem (2013) ncbi
rabbit polyclonal
  • western blot; human; fig 5
EMD Millipore LOC525863 antibody (Millipore, 07-108) was used in western blot on human samples (fig 5). PLoS ONE (2013) ncbi
Articles Reviewed
  1. Ryu K, Nandu T, Kim J, Challa S, DeBerardinis R, Kraus W. Metabolic regulation of transcription through compartmentalized NAD+ biosynthesis. Science. 2018;360: pubmed publisher
  2. Parira T, Figueroa G, Laverde A, Casteleiro G, Gomez Hernandez M, FERNANDEZ LIMA F, et al. Novel detection of post-translational modifications in human monocyte-derived dendritic cells after chronic alcohol exposure: Role of inflammation regulator H4K12ac. Sci Rep. 2017;7:11236 pubmed publisher
  3. Mahajan K, Malla P, Lawrence H, Chen Z, Kumar Sinha C, Malik R, et al. ACK1/TNK2 Regulates Histone H4 Tyr88-phosphorylation and AR Gene Expression in Castration-Resistant Prostate Cancer. Cancer Cell. 2017;31:790-803.e8 pubmed publisher
  4. Bourgeois C, Satou R, Prieto M. HDAC9 is an epigenetic repressor of kidney angiotensinogen establishing a sex difference. Biol Sex Differ. 2017;8:18 pubmed publisher
  5. Jha K, Tripurani S, Johnson G. TSSK6 is required for γH2AX formation and the histone-to-protamine transition during spermiogenesis. J Cell Sci. 2017;130:1835-1844 pubmed publisher
  6. Jia X, Chen J, Megger D, Zhang X, Kozlowski M, Zhang L, et al. Label-free Proteomic Analysis of Exosomes Derived from Inducible Hepatitis B Virus-Replicating HepAD38 Cell Line. Mol Cell Proteomics. 2017;16:S144-S160 pubmed publisher
  7. He Y, Selvaraju S, Curtin M, Jakob C, Zhu H, Comess K, et al. The EED protein-protein interaction inhibitor A-395 inactivates the PRC2 complex. Nat Chem Biol. 2017;13:389-395 pubmed publisher
  8. Makki M, Haqqi T. Histone Deacetylase Inhibitor Vorinostat (SAHA) Suppresses IL-1?-Induced Matrix Metallopeptidase-13 Expression by Inhibiting IL-6 in Osteoarthritis Chondrocyte. Am J Pathol. 2016;186:2701-8 pubmed publisher
  9. Yang J, Song T, Jo C, Park J, Lee H, Song I, et al. Differential regulation of the histone chaperone HIRA during muscle cell differentiation by a phosphorylation switch. Exp Mol Med. 2016;48:e252 pubmed publisher
  10. Nelson D, Jaber Hijazi F, Cole J, Robertson N, Pawlikowski J, Norris K, et al. Mapping H4K20me3 onto the chromatin landscape of senescent cells indicates a function in control of cell senescence and tumor suppression through preservation of genetic and epigenetic stability. Genome Biol. 2016;17:158 pubmed publisher
  11. Wu X, Zhao L, Chen Z, Ji X, Qiao X, Jin Y, et al. FLCN Maintains the Leucine Level in Lysosome to Stimulate mTORC1. PLoS ONE. 2016;11:e0157100 pubmed publisher
  12. Diamant G, Bahat A, Dikstein R. The elongation factor Spt5 facilitates transcription initiation for rapid induction of inflammatory-response genes. Nat Commun. 2016;7:11547 pubmed publisher
  13. Zheng Q, Liu H, Ye J, Zhang H, Jia Z, Cao J. Nuclear distribution of eIF3g and its interacting nuclear proteins in breast cancer cells. Mol Med Rep. 2016;13:2973-80 pubmed publisher
  14. Ouyang S, Song Y, Tian Y, Chen Y, Yu X, Wang D. RNF8 deficiency results in neurodegeneration in mice. Neurobiol Aging. 2015;36:2850-2860 pubmed publisher
  15. Sarma P, Bag I, Ramaiah M, Kamal A, Bhadra U, Pal Bhadra M. Bisindole-PBD regulates breast cancer cell proliferation via SIRT-p53 axis. Cancer Biol Ther. 2015;16:1486-501 pubmed publisher
  16. Sedic M, Skibinski A, Brown N, Gallardo M, Mulligan P, Martinez P, et al. Haploinsufficiency for BRCA1 leads to cell-type-specific genomic instability and premature senescence. Nat Commun. 2015;6:7505 pubmed publisher
  17. Huang X, Shen M, Wang L, Yu F, Wu W, Liu H. Effects of tributyltin chloride on developing mouse oocytes and preimplantation embryos. Microsc Microanal. 2015;21:358-67 pubmed publisher
  18. Kim B, Serebreni L, Fallica J, Hamdan O, Wang L, Johnston L, et al. Cyclin-dependent kinase five mediates activation of lung xanthine oxidoreductase in response to hypoxia. PLoS ONE. 2015;10:e0124189 pubmed publisher
  19. Varshney D, Vavrova Anderson J, Oler A, Cowling V, Cairns B, White R. SINE transcription by RNA polymerase III is suppressed by histone methylation but not by DNA methylation. Nat Commun. 2015;6:6569 pubmed publisher
  20. Nakshatri H, Appaiah H, Anjanappa M, Gilley D, Tanaka H, Badve S, et al. NF-κB-dependent and -independent epigenetic modulation using the novel anti-cancer agent DMAPT. Cell Death Dis. 2015;6:e1608 pubmed publisher
  21. Inaba J, McConnell E, Davis K. Lunasin sensitivity in non-small cell lung cancer cells is linked to suppression of integrin signaling and changes in histone acetylation. Int J Mol Sci. 2014;15:23705-24 pubmed publisher
  22. Shirakata Y, Hiradate Y, Inoue H, Sato E, Tanemura K. Histone h4 modification during mouse spermatogenesis. J Reprod Dev. 2014;60:383-7 pubmed
  23. Kumar P P, Emechebe U, Smith R, Franklin S, Moore B, Yandell M, et al. Coordinated control of senescence by lncRNA and a novel T-box3 co-repressor complex. elife. 2014;3: pubmed publisher
  24. Tafrova J, Tafrov S. Human histone acetyltransferase 1 (Hat1) acetylates lysine 5 of histone H2A in vivo. Mol Cell Biochem. 2014;392:259-72 pubmed publisher
  25. Sanders Y, Hagood J, Liu H, Zhang W, Ambalavanan N, Thannickal V. Histone deacetylase inhibition promotes fibroblast apoptosis and ameliorates pulmonary fibrosis in mice. Eur Respir J. 2014;43:1448-58 pubmed publisher
  26. Lauffer B, Mintzer R, Fong R, Mukund S, Tam C, Zilberleyb I, et al. Histone deacetylase (HDAC) inhibitor kinetic rate constants correlate with cellular histone acetylation but not transcription and cell viability. J Biol Chem. 2013;288:26926-43 pubmed publisher
  27. Rass E, Chandramouly G, Zha S, Alt F, Xie A. Ataxia telangiectasia mutated (ATM) is dispensable for endonuclease I-SceI-induced homologous recombination in mouse embryonic stem cells. J Biol Chem. 2013;288:7086-95 pubmed publisher
  28. Shukla S, Sharma H, Abbas A, MacLennan G, Fu P, Danielpour D, et al. Upregulation of SATB1 is associated with prostate cancer aggressiveness and disease progression. PLoS ONE. 2013;8:e53527 pubmed publisher