This is a Validated Antibody Database (VAD) review about cow KAT2B, based on 12 published articles (read how Labome selects the articles), using KAT2B antibody in all methods. It is aimed to help Labome visitors find the most suited KAT2B antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
KAT2B synonym: PCAF; histone acetyltransferase KAT2B; p300/CBP-associated factor

Cell Signaling Technology
rabbit monoclonal (C14G9)
  • immunocytochemistry; mouse; loading ...; fig 4e
  • western blot; mouse; loading ...; fig 4d
Cell Signaling Technology KAT2B antibody (Cell Signaling, 3378S) was used in immunocytochemistry on mouse samples (fig 4e) and in western blot on mouse samples (fig 4d). J Clin Invest (2019) ncbi
rabbit monoclonal (C14G9)
  • western blot; human; loading ...; fig 3a
Cell Signaling Technology KAT2B antibody (Cell Signaling, 3378) was used in western blot on human samples (fig 3a). Biosci Rep (2018) ncbi
rabbit monoclonal (C14G9)
  • chromatin immunoprecipitation; human; loading ...; fig 5e
In order to assess the effect of TNF-alpha inhibitors on monocyte chemoattractant protein-1, Cell Signaling Technology KAT2B antibody (Cell Signaling, 3378) was used in chromatin immunoprecipitation on human samples (fig 5e). Mol Immunol (2017) ncbi
rabbit monoclonal (C14G9)
  • western blot; human; 1:200; fig st1
In order to identify and characterize alterations in signal transduction that occur during the development Lapatinib resistance, Cell Signaling Technology KAT2B antibody (Cell Signaling, 3378) was used in western blot on human samples at 1:200 (fig st1). Nat Commun (2016) ncbi
rabbit monoclonal (C14G9)
  • immunoprecipitation; human; loading ...; fig 6a
  • western blot; human; loading ...; fig 6c
In order to examine the mechanisms by which IL-6/STAT3 signaling and TIMP-1 modulate the crosstalk between tumor cells and cancer associated fibroblasts in the tumor microenvironment, Cell Signaling Technology KAT2B antibody (Cell Signaling, 3378) was used in immunoprecipitation on human samples (fig 6a) and in western blot on human samples (fig 6c). Cell Signal (2016) ncbi
rabbit monoclonal (C14G9)
  • RNA immunoprecipitation; human; fig 3
  • western blot; human; fig s3
Cell Signaling Technology KAT2B antibody (Cell Signaling, 3378S) was used in RNA immunoprecipitation on human samples (fig 3) and in western blot on human samples (fig s3). Genome Biol (2016) ncbi
rabbit monoclonal (C14G9)
  • other; mouse; 1:500; fig s1
In order to identify host signaling dynamics upon Burkholderia spp. infection by a reverse-phase protein microarray-based screen, Cell Signaling Technology KAT2B antibody (Cell Signaling, 3378) was used in other on mouse samples at 1:500 (fig s1). Front Microbiol (2015) ncbi
rabbit monoclonal (C14G9)
  • western blot; human; fig 2
Cell Signaling Technology KAT2B antibody (Cell Signaling Technologies, 3378S) was used in western blot on human samples (fig 2). Chem Biol (2015) ncbi
rabbit monoclonal (C14G9)
  • western blot; human; 1:1000; fig 1
In order to study stress erythropoiesis regulated by an acetate switch, Cell Signaling Technology KAT2B antibody (Cell Signaling Technology, 3378) was used in western blot on human samples at 1:1000 (fig 1). Nat Med (2014) ncbi
rabbit monoclonal (C14G9)
  • chromatin immunoprecipitation; mouse
In order to study the modulation of CD4 T-cell senescence and cytokine production and the roles played by Menin and Bach2, Cell Signaling Technology KAT2B antibody (Cell Signaling Technology, 3378) was used in chromatin immunoprecipitation on mouse samples . Nat Commun (2014) ncbi
rabbit monoclonal (C14G9)
  • western blot; mouse
Cell Signaling Technology KAT2B antibody (CST, 3378) was used in western blot on mouse samples . J Clin Invest (2013) ncbi
rabbit monoclonal (C14G9)
  • western blot; rat
Cell Signaling Technology KAT2B antibody (Cell Signaling, 3378) was used in western blot on rat samples . Neuropsychopharmacology (2010) ncbi
Articles Reviewed
  1. Bartolomé A, Zhu C, Sussel L, Pajvani U. Notch signaling dynamically regulates adult β cell proliferation and maturity. J Clin Invest. 2019;129:268-280 pubmed publisher
  2. Zhang Y, Cao Y, Zhang L, Feng C, Zhou G, Wen G. Apigenin inhibits C5a-induced proliferation of human nasopharyngeal carcinoma cells through down-regulation of C5aR. Biosci Rep. 2018;38: pubmed publisher
  3. Lin Y, Lin Y, Huang M, Kuo P, Wu C, Lee M, et al. Tumor necrosis factor-alpha inhibitors suppress CCL2 chemokine in monocytes via epigenetic modification. Mol Immunol. 2017;83:82-91 pubmed publisher
  4. Treindl F, Ruprecht B, Beiter Y, Schultz S, Döttinger A, Staebler A, et al. A bead-based western for high-throughput cellular signal transduction analyses. Nat Commun. 2016;7:12852 pubmed publisher
  5. Zheng X, Xu M, Yao B, Wang C, Jia Y, Liu Q. IL-6/STAT3 axis initiated CAFs via up-regulating TIMP-1 which was attenuated by acetylation of STAT3 induced by PCAF in HCC microenvironment. Cell Signal. 2016;28:1314-24 pubmed publisher
  6. G Hendrickson D, Kelley D, Tenen D, BERNSTEIN B, Rinn J. Widespread RNA binding by chromatin-associated proteins. Genome Biol. 2016;17:28 pubmed publisher
  7. Chiang C, Uzoma I, Lane D, Memišević V, Alem F, Yao K, et al. A reverse-phase protein microarray-based screen identifies host signaling dynamics upon Burkholderia spp. infection. Front Microbiol. 2015;6:683 pubmed publisher
  8. Montgomery D, Sorum A, Guasch L, Nicklaus M, Meier J. Metabolic Regulation of Histone Acetyltransferases by Endogenous Acyl-CoA Cofactors. Chem Biol. 2015;22:1030-1039 pubmed publisher
  9. Xu M, Nagati J, Xie J, Li J, Walters H, Moon Y, et al. An acetate switch regulates stress erythropoiesis. Nat Med. 2014;20:1018-26 pubmed publisher
  10. Kuwahara M, Suzuki J, Tofukuji S, Yamada T, Kanoh M, Matsumoto A, et al. The Menin-Bach2 axis is critical for regulating CD4 T-cell senescence and cytokine homeostasis. Nat Commun. 2014;5:3555 pubmed publisher
  11. Ravnskjaer K, Hogan M, Lackey D, Tora L, Dent S, Olefsky J, et al. Glucagon regulates gluconeogenesis through KAT2B- and WDR5-mediated epigenetic effects. J Clin Invest. 2013;123:4318-28 pubmed publisher
  12. Bousiges O, Vasconcelos A, Neidl R, Cosquer B, Herbeaux K, Panteleeva I, et al. Spatial memory consolidation is associated with induction of several lysine-acetyltransferase (histone acetyltransferase) expression levels and H2B/H4 acetylation-dependent transcriptional events in the rat hippocampus. Neuropsychopharmacology. 2010;35:2521-37 pubmed publisher