This is a Validated Antibody Database (VAD) review about cow JAK1, based on 15 published articles (read how Labome selects the articles), using JAK1 antibody in all methods. It is aimed to help Labome visitors find the most suited JAK1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
JAK1 synonym: tyrosine-protein kinase JAK1; Janus kinase 1 (a protein tyrosine kinase)

Cell Signaling Technology
rabbit polyclonal
  • western blot; mouse; loading ...; fig 3d
Cell Signaling Technology JAK1 antibody (Cell Signaling, 3331) was used in western blot on mouse samples (fig 3d). Cancer Discov (2019) ncbi
rabbit polyclonal
  • western blot; mouse; loading ...; fig 1f
Cell Signaling Technology JAK1 antibody (Cell Signaling, 3331) was used in western blot on mouse samples (fig 1f). Cell (2018) ncbi
rabbit polyclonal
  • western blot; mouse; loading ...; fig 1f
Cell Signaling Technology JAK1 antibody (Cell Signaling, 3332) was used in western blot on mouse samples (fig 1f). Cell (2018) ncbi
rabbit polyclonal
  • western blot; human; loading ...; fig 1b
Cell Signaling Technology JAK1 antibody (Cell Signaling Technologies, 3332) was used in western blot on human samples (fig 1b). Oncoimmunology (2018) ncbi
rabbit polyclonal
  • western blot; human; loading ...; fig 9a
Cell Signaling Technology JAK1 antibody (Cell Signaling, 3331) was used in western blot on human samples (fig 9a). Nature (2017) ncbi
rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig 3a
Cell Signaling Technology JAK1 antibody (Cell Signaling, 3331) was used in western blot on human samples at 1:1000 (fig 3a). Nat Commun (2016) ncbi
rabbit polyclonal
  • western blot; human; loading ...; fig 5a
Cell Signaling Technology JAK1 antibody (cell signalling, 3331) was used in western blot on human samples (fig 5a). PLoS Med (2016) ncbi
rabbit polyclonal
  • western blot; mouse; loading ...; fig s8
In order to find that that vascular endothelial growth factor 165b prevents activation of vascular endothelial growth factor receptor 1-STAT3 signaling by vascular endothelial growth factor 165a, Cell Signaling Technology JAK1 antibody (Cell Signaling, 3331) was used in western blot on mouse samples (fig s8). Circ Res (2017) ncbi
rabbit polyclonal
  • western blot; mouse; loading ...; fig 4
In order to study mouse models of dilated cardiomyopathy to study calcium signaling, Cell Signaling Technology JAK1 antibody (Cell Signaling, 3331) was used in western blot on mouse samples (fig 4). PLoS ONE (2016) ncbi
rabbit polyclonal
  • western blot; human; 1:200; loading ...; fig s4
Cell Signaling Technology JAK1 antibody (cell signalling, 3331) was used in western blot on human samples at 1:200 (fig s4). Oncotarget (2017) ncbi
rabbit polyclonal
  • western blot; human; 1:500; loading ...; fig s4
Cell Signaling Technology JAK1 antibody (cell signalling, 3332) was used in western blot on human samples at 1:500 (fig s4). Oncotarget (2017) ncbi
rabbit polyclonal
  • western blot; mouse; 1:1000; loading ...; fig 9a
Cell Signaling Technology JAK1 antibody (Cell Signaling Technology, 3331) was used in western blot on mouse samples at 1:1000 (fig 9a). Drug Des Devel Ther (2016) ncbi
rabbit polyclonal
  • immunohistochemistry; mouse; loading ...; fig 3g
  • western blot; human; loading ...; fig 3f
Cell Signaling Technology JAK1 antibody (Cell Signaling, 3331) was used in immunohistochemistry on mouse samples (fig 3g) and in western blot on human samples (fig 3f). J Clin Invest (2016) ncbi
rabbit polyclonal
  • western blot; mouse; 1:500; loading ...; fig 7a
In order to demonstrate that Ndfip1/Ndfip2 regulate cross talk between T-cell receptor and cytokine signaling pathways, Cell Signaling Technology JAK1 antibody (Cell Signaling Technologies, 3332) was used in western blot on mouse samples at 1:500 (fig 7a). Nat Commun (2016) ncbi
rabbit polyclonal
  • western blot; human; 1:1000; fig 4
In order to analyze multidrug resistant human cancer cells and autocrime cytokine/JAK/STAT-signaling induces kynurenin synthesis, Cell Signaling Technology JAK1 antibody (Cell Signaling Technology, 3331) was used in western blot on human samples at 1:1000 (fig 4). PLoS ONE (2015) ncbi
rabbit polyclonal
  • western blot; hamsters
Cell Signaling Technology JAK1 antibody (Cell Signaling, 3331) was used in western blot on hamsters samples . Front Cell Infect Microbiol (2014) ncbi
rabbit polyclonal
  • western blot; human; 1:300
Cell Signaling Technology JAK1 antibody (Cell Signaling, 3331) was used in western blot on human samples at 1:300. Cell Death Dis (2014) ncbi
Articles Reviewed
  1. Biffi G, Oni T, Spielman B, Hao Y, Elyada E, Park Y, et al. IL1-Induced JAK/STAT Signaling Is Antagonized by TGFβ to Shape CAF Heterogeneity in Pancreatic Ductal Adenocarcinoma. Cancer Discov. 2019;9:282-301 pubmed publisher
  2. Xu X, Xu J, Wu J, Hu Y, Han Y, Gu Y, et al. Phosphorylation-Mediated IFN-γR2 Membrane Translocation Is Required to Activate Macrophage Innate Response. Cell. 2018;175:1336-1351.e17 pubmed publisher
  3. Luo N, Formisano L, Gonzalez Ericsson P, Sanchez V, Dean P, Opalenik S, et al. Melanoma response to anti-PD-L1 immunotherapy requires JAK1 signaling, but not JAK2. Oncoimmunology. 2018;7:e1438106 pubmed publisher
  4. Patel S, Sanjana N, Kishton R, Eidizadeh A, Vodnala S, Cam M, et al. Identification of essential genes for cancer immunotherapy. Nature. 2017;548:537-542 pubmed publisher
  5. Eletto D, Burns S, Angulo I, Plagnol V, Gilmour K, Henriquez F, et al. Biallelic JAK1 mutations in immunodeficient patient with mycobacterial infection. Nat Commun. 2016;7:13992 pubmed publisher
  6. Li Y, Buijs Gladdines J, Canté Barrett K, Stubbs A, Vroegindeweij E, Smits W, et al. IL-7 Receptor Mutations and Steroid Resistance in Pediatric T cell Acute Lymphoblastic Leukemia: A Genome Sequencing Study. PLoS Med. 2016;13:e1002200 pubmed publisher
  7. Ganta V, Choi M, Kutateladze A, Annex B. VEGF165b Modulates Endothelial VEGFR1-STAT3 Signaling Pathway and Angiogenesis in Human and Experimental Peripheral Arterial Disease. Circ Res. 2017;120:282-295 pubmed publisher
  8. Ramratnam M, Salama G, Sharma R, Wang D, Smith S, Banerjee S, et al. Gene-Targeted Mice with the Human Troponin T R141W Mutation Develop Dilated Cardiomyopathy with Calcium Desensitization. PLoS ONE. 2016;11:e0167681 pubmed publisher
  9. Bonan S, Albrengues J, Grasset E, Kuzet S, Nottet N, Bourget I, et al. Membrane-bound ICAM-1 contributes to the onset of proinvasive tumor stroma by controlling acto-myosin contractility in carcinoma-associated fibroblasts. Oncotarget. 2017;8:1304-1320 pubmed publisher
  10. He Y, Yan Y, Zhang H, Lin Y, Chen Y, Yan Y, et al. Methyl salicylate 2-O-?-d-lactoside alleviates the pathological progression of pristane-induced systemic lupus erythematosus-like disease in mice via suppression of inflammatory response and signal transduction. Drug Des Devel Ther. 2016;10:3183-3196 pubmed
  11. Yasuda T, Fukada T, Nishida K, Nakayama M, Matsuda M, Miura I, et al. Hyperactivation of JAK1 tyrosine kinase induces stepwise, progressive pruritic dermatitis. J Clin Invest. 2016;126:2064-76 pubmed publisher
  12. O Leary C, Riling C, Spruce L, Ding H, Kumar S, Deng G, et al. Ndfip-mediated degradation of Jak1 tunes cytokine signalling to limit expansion of CD4+ effector T cells. Nat Commun. 2016;7:11226 pubmed publisher
  13. Campia I, Buondonno I, Castella B, Rolando B, Kopecka J, Gazzano E, et al. An Autocrine Cytokine/JAK/STAT-Signaling Induces Kynurenine Synthesis in Multidrug Resistant Human Cancer Cells. PLoS ONE. 2015;10:e0126159 pubmed publisher
  14. Hall J, Sun J, Slade J, Kintner J, Bambino M, Whittimore J, et al. Host nectin-1 is required for efficient Chlamydia trachomatis serovar E development. Front Cell Infect Microbiol. 2014;4:158 pubmed publisher
  15. Mathieu M, Miles A, Ahmad M, Buczek M, Pockley A, Rees R, et al. The helicase HAGE prevents interferon-?-induced PML expression in ABCB5+ malignant melanoma-initiating cells by promoting the expression of SOCS1. Cell Death Dis. 2014;5:e1061 pubmed publisher