This is a Validated Antibody Database (VAD) review about cow ITGA6, based on 25 published articles (read how Labome selects the articles), using ITGA6 antibody in all methods. It is aimed to help Labome visitors find the most suited ITGA6 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
ITGA6 synonym: integrin alpha-6; integrin, alpha 6

BioLegend
rat monoclonal (GoH3)
  • flow cytometry; mouse; loading ...; fig 2a
  • flow cytometry; human; loading ...; fig 9b
BioLegend ITGA6 antibody (BioLegend, GoH3) was used in flow cytometry on mouse samples (fig 2a) and in flow cytometry on human samples (fig 9b). J Cell Biol (2018) ncbi
rat monoclonal (GoH3)
  • immunohistochemistry; mouse; 1:100; loading ...; fig 4a
BioLegend ITGA6 antibody (Biolegend, 313606) was used in immunohistochemistry on mouse samples at 1:100 (fig 4a). Nature (2018) ncbi
rat monoclonal (GoH3)
  • flow cytometry; mouse; loading ...; fig s3c
BioLegend ITGA6 antibody (BioLegend, GoH3) was used in flow cytometry on mouse samples (fig s3c). J Clin Invest (2017) ncbi
rat monoclonal (GoH3)
  • immunohistochemistry - frozen section; mouse; 1:150; loading ...; fig 5a
In order to propose that macrophage-TNF-induced AKT/beta-catenin signaling in Lgr5(+) hair follicle stem cells is important for promoting hair follicle cycling and neogenesis after wounding, BioLegend ITGA6 antibody (BioLegend, GoH3) was used in immunohistochemistry - frozen section on mouse samples at 1:150 (fig 5a). Nat Commun (2017) ncbi
rat monoclonal (GoH3)
  • flow cytometry; mouse; loading ...; fig 3e
BioLegend ITGA6 antibody (BioLegend, GoH3) was used in flow cytometry on mouse samples (fig 3e). Science (2017) ncbi
rat monoclonal (GoH3)
  • flow cytometry; human; 1:25; loading ...; fig 3a
In order to define the interaction between LATS1/2 and the estrogen receptor signaling in breast cancer initiation., BioLegend ITGA6 antibody (BioLegend, GoH3) was used in flow cytometry on human samples at 1:25 (fig 3a). Nature (2017) ncbi
rat monoclonal (GoH3)
  • flow cytometry; mouse; fig 2a
BioLegend ITGA6 antibody (BioLegend, GoH3) was used in flow cytometry on mouse samples (fig 2a). Sci Rep (2016) ncbi
rat monoclonal (GoH3)
  • flow cytometry; mouse; loading ...; fig 1a
BioLegend ITGA6 antibody (BioLegend, GoH3) was used in flow cytometry on mouse samples (fig 1a). PLoS Pathog (2016) ncbi
rat monoclonal (GoH3)
  • flow cytometry; human; loading ...; fig 4
In order to discuss the relationship between TGF-beta and MYC in basal subtype breast cancers, BioLegend ITGA6 antibody (BioLegend, 313606) was used in flow cytometry on human samples (fig 4). Cancer Res (2016) ncbi
rat monoclonal (GoH3)
  • flow cytometry; human; loading ...; tbl s1
In order to explore how junctional adhesion molecule family members differentially regulate CXCR4 function and CXCL12 secretion in the bone marrow niche, BioLegend ITGA6 antibody (Biolegend, 313618) was used in flow cytometry on human samples (tbl s1). Stem Cells (2016) ncbi
rat monoclonal (GoH3)
  • other; human; loading ...; fig st1
In order to use size exclusion chromatography-microsphere-based affinity proteomics to study clinical samples obtained from pediatric acute leukemia patients, BioLegend ITGA6 antibody (BIOLegend, GoH3) was used in other on human samples (fig st1). Mol Cell Proteomics (2016) ncbi
rat monoclonal (GoH3)
  • immunohistochemistry; mouse; fig s1
In order to research skin-resident memory T cell homeostasis and lymphoma mediated by hair follicle-derived IL-7 and IL-15, BioLegend ITGA6 antibody (BioLegend, GoH3) was used in immunohistochemistry on mouse samples (fig s1). Nat Med (2015) ncbi
rat monoclonal (GoH3)
  • western blot; human; 1:1000
BioLegend ITGA6 antibody (BioLegend, GoH3) was used in western blot on human samples at 1:1000. Hum Mol Genet (2015) ncbi
rat monoclonal (GoH3)
  • flow cytometry; mouse; fig s6
BioLegend ITGA6 antibody (BioLegend, 313608) was used in flow cytometry on mouse samples (fig s6). Proc Natl Acad Sci U S A (2015) ncbi
rat monoclonal (GoH3)
  • flow cytometry; human; fig 1
In order to study and identify critical cell lineage-dependent transduction bias to model breast cancer properly, BioLegend ITGA6 antibody (BioLegend, GoH3) was used in flow cytometry on human samples (fig 1). Nat Commun (2015) ncbi
rat monoclonal (GoH3)
  • flow cytometry; human; fig 5
In order to study the role of alpha-4 integrin in the mechanism by which CD82 modulates cell adhesion, BioLegend ITGA6 antibody (BioLegend, GoH3) was used in flow cytometry on human samples (fig 5). Mol Biol Cell (2014) ncbi
R&D Systems
rat monoclonal (GoH3)
  • flow cytometry; mouse; fig s13a
R&D Systems ITGA6 antibody (R & D, FAB13501P) was used in flow cytometry on mouse samples (fig s13a). Science (2018) ncbi
rat monoclonal (GoH3)
  • flow cytometry; mouse; fig 2
In order to characterize prolactin receptor signaling for mammary gland development by a novel nectin-mediated cell adhesion apparatus, R&D Systems ITGA6 antibody (R&D Systems, FAB13501) was used in flow cytometry on mouse samples (fig 2). J Biol Chem (2016) ncbi
rat monoclonal (GoH3)
  • blocking or activating experiments; human; loading ...; fig 2a
  • flow cytometry; human; loading ...; fig 2b
R&D Systems ITGA6 antibody (R&D Systems, MAB13501) was used in blocking or activating experiments on human samples (fig 2a) and in flow cytometry on human samples (fig 2b). Cell Adh Migr (2015) ncbi
rat monoclonal (GoH3)
  • immunohistochemistry - frozen section; mouse; 1:500
R&D Systems ITGA6 antibody (R&D Systems, GoH3) was used in immunohistochemistry - frozen section on mouse samples at 1:500. J Cell Biol (2015) ncbi
rat monoclonal (GoH3)
  • immunohistochemistry; mouse; 1:250; fig 1
R&D Systems ITGA6 antibody (R&D, GoH3) was used in immunohistochemistry on mouse samples at 1:250 (fig 1). Nat Commun (2015) ncbi
rat monoclonal (GoH3)
  • blocking or activating experiments; human
R&D Systems ITGA6 antibody (R&D Systems, GOH3) was used in blocking or activating experiments on human samples . PLoS ONE (2013) ncbi
Abcam
rabbit polyclonal
  • western blot; dog; loading ...; fig 5a
Abcam ITGA6 antibody (Abcam, ab97760) was used in western blot on dog samples (fig 5a). Oncogene (2017) ncbi
rabbit polyclonal
  • flow cytometry; human; 1:50; loading ...; fig 5k
In order to analyze the complexing of cellular prion protein with co-chaperone Hsp70/90 organizing protein in glioblastoma stem-like cells, Abcam ITGA6 antibody (Abcam, ab97760) was used in flow cytometry on human samples at 1:50 (fig 5k). Stem Cell Res Ther (2017) ncbi
rabbit polyclonal
  • western blot; human
In order to study the role of alpha-4 integrin in the mechanism by which CD82 modulates cell adhesion, Abcam ITGA6 antibody (Abcam, ab97760) was used in western blot on human samples . Mol Biol Cell (2014) ncbi
rabbit polyclonal
  • western blot; human; 1:1000
Abcam ITGA6 antibody (Abcam, ab97760) was used in western blot on human samples at 1:1000. Br J Cancer (2013) ncbi
Articles Reviewed
  1. Albrengues J, Shields M, Ng D, Park C, Ambrico A, Poindexter M, et al. Neutrophil extracellular traps produced during inflammation awaken dormant cancer cells in mice. Science. 2018;361: pubmed publisher
  2. Casey A, Sinha A, Singhania R, Livingstone J, Waterhouse P, Tharmapalan P, et al. Mammary molecular portraits reveal lineage-specific features and progenitor cell vulnerabilities. J Cell Biol. 2018;217:2951-2974 pubmed publisher
  3. Liakath Ali K, Mills E, Sequeira I, Lichtenberger B, Pisco A, Sipilä K, et al. An evolutionarily conserved ribosome-rescue pathway maintains epidermal homeostasis. Nature. 2018;556:376-380 pubmed publisher
  4. Zhang K, Myllymäki S, Gao P, Devarajan R, Kytölä V, Nykter M, et al. Oncogenic K-Ras upregulates ITGA6 expression via FOSL1 to induce anoikis resistance and synergizes with αV-Class integrins to promote EMT. Oncogene. 2017;36:5681-5694 pubmed publisher
  5. Bagchi S, He Y, Zhang H, Cao L, Van Rhijn I, Moody D, et al. CD1b-autoreactive T cells contribute to hyperlipidemia-induced skin inflammation in mice. J Clin Invest. 2017;127:2339-2352 pubmed publisher
  6. Iglesia R, Prado M, Cruz L, Martins V, Santos T, Lopes M. Engagement of cellular prion protein with the co-chaperone Hsp70/90 organizing protein regulates the proliferation of glioblastoma stem-like cells. Stem Cell Res Ther. 2017;8:76 pubmed publisher
  7. Wang X, Chen H, Tian R, Zhang Y, Drutskaya M, Wang C, et al. Macrophages induce AKT/β-catenin-dependent Lgr5+ stem cell activation and hair follicle regeneration through TNF. Nat Commun. 2017;8:14091 pubmed publisher
  8. Zhao C, Cai S, Shin K, Lim A, Kalisky T, Lu W, et al. Stromal Gli2 activity coordinates a niche signaling program for mammary epithelial stem cells. Science. 2017;356: pubmed publisher
  9. Britschgi A, Duss S, Kim S, Couto J, Brinkhaus H, Koren S, et al. The Hippo kinases LATS1 and 2 control human breast cell fate via crosstalk with ER?. Nature. 2017;541:541-545 pubmed publisher
  10. Yokota Nakatsuma A, Ohoka Y, Takeuchi H, Song S, Iwata M. Beta 1-integrin ligation and TLR ligation enhance GM-CSF-induced ALDH1A2 expression in dendritic cells, but differentially regulate their anti-inflammatory properties. Sci Rep. 2016;6:37914 pubmed publisher
  11. Quantius J, Schmoldt C, Vazquez Armendariz A, Becker C, El Agha E, Wilhelm J, et al. Influenza Virus Infects Epithelial Stem/Progenitor Cells of the Distal Lung: Impact on Fgfr2b-Driven Epithelial Repair. PLoS Pathog. 2016;12:e1005544 pubmed publisher
  12. Cichon M, Moruzzi M, Shqau T, Miller E, Mehner C, Ethier S, et al. MYC Is a Crucial Mediator of TGF?-Induced Invasion in Basal Breast Cancer. Cancer Res. 2016;76:3520-30 pubmed publisher
  13. Chang C, Hale S, Cox C, Blair A, Kronsteiner B, Grabowska R, et al. Junctional Adhesion Molecule-A Is Highly Expressed on Human Hematopoietic Repopulating Cells and Associates with the Key Hematopoietic Chemokine Receptor CXCR4. Stem Cells. 2016;34:1664-78 pubmed publisher
  14. Kanderová V, Kuzilkova D, Stuchly J, Vaskova M, Brdicka T, Fiser K, et al. High-resolution Antibody Array Analysis of Childhood Acute Leukemia Cells. Mol Cell Proteomics. 2016;15:1246-61 pubmed publisher
  15. Kitayama M, Mizutani K, Maruoka M, Mandai K, Sakakibara S, Ueda Y, et al. A Novel Nectin-mediated Cell Adhesion Apparatus That Is Implicated in Prolactin Receptor Signaling for Mammary Gland Development. J Biol Chem. 2016;291:5817-31 pubmed publisher
  16. Adachi T, Kobayashi T, Sugihara E, Yamada T, Ikuta K, Pittaluga S, et al. Hair follicle-derived IL-7 and IL-15 mediate skin-resident memory T cell homeostasis and lymphoma. Nat Med. 2015;21:1272-9 pubmed publisher
  17. Martin A, Cardoso A, Selistre de Araujo H, Cominetti M. Recombinant disintegrin domain of human ADAM9 inhibits migration and invasion of DU145 prostate tumor cells. Cell Adh Migr. 2015;9:293-9 pubmed publisher
  18. Virts E, Jankowska A, MacKay C, Glaas M, Wiek C, Kelich S, et al. AluY-mediated germline deletion, duplication and somatic stem cell reversion in UBE2T defines a new subtype of Fanconi anemia. Hum Mol Genet. 2015;24:5093-108 pubmed publisher
  19. Stewart R, Zubek A, Rosowski K, Schreiner S, Horsley V, King M. Nuclear-cytoskeletal linkages facilitate cross talk between the nucleus and intercellular adhesions. J Cell Biol. 2015;209:403-18 pubmed publisher
  20. Pathania R, Ramachandran S, Elangovan S, Padia R, Yang P, Cinghu S, et al. DNMT1 is essential for mammary and cancer stem cell maintenance and tumorigenesis. Nat Commun. 2015;6:6910 pubmed publisher
  21. Davis F, Janoshazi A, Janardhan K, Steinckwich N, D Agostin D, Petranka J, et al. Essential role of Orai1 store-operated calcium channels in lactation. Proc Natl Acad Sci U S A. 2015;112:5827-32 pubmed publisher
  22. Hines W, Yaswen P, Bissell M. Modelling breast cancer requires identification and correction of a critical cell lineage-dependent transduction bias. Nat Commun. 2015;6:6927 pubmed publisher
  23. Termini C, Cotter M, Marjon K, Buranda T, Lidke K, Gillette J. The membrane scaffold CD82 regulates cell adhesion by altering α4 integrin stability and molecular density. Mol Biol Cell. 2014;25:1560-73 pubmed publisher
  24. Kinoshita T, Nohata N, Hanazawa T, Kikkawa N, Yamamoto N, Yoshino H, et al. Tumour-suppressive microRNA-29s inhibit cancer cell migration and invasion by targeting laminin-integrin signalling in head and neck squamous cell carcinoma. Br J Cancer. 2013;109:2636-45 pubmed publisher
  25. Wondimu Z, Omrani S, Ishikawa T, Javed F, Oikawa Y, Virtanen I, et al. A novel monoclonal antibody to human laminin ?5 chain strongly inhibits integrin-mediated cell adhesion and migration on laminins 511 and 521. PLoS ONE. 2013;8:e53648 pubmed publisher