This is a Validated Antibody Database (VAD) review about cow HIF1A, based on 70 published articles (read how Labome selects the articles), using HIF1A antibody in all methods. It is aimed to help Labome visitors find the most suited HIF1A antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
HIF1A synonym: hypoxia-inducible factor 1-alpha; HIF-1-alpha; HIF1-alpha; hypoxia inducible factor 1 alpha subunit; hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)

Knockout validation
Novus Biologicals
mouse monoclonal (H1alpha67)
  • western blot knockout validation; mouse; loading ...; fig 2f
Novus Biologicals HIF1A antibody (Novus, NB100-123) was used in western blot knockout validation on mouse samples (fig 2f). Nat Commun (2016) ncbi
Novus Biologicals
mouse monoclonal (H1alpha67)
  • western blot knockout validation; mouse; fig 3
  • western blot; human; fig 3
Novus Biologicals HIF1A antibody (Novus Biologicals, NB100-105) was used in western blot knockout validation on mouse samples (fig 3) and in western blot on human samples (fig 3). Sci Rep (2016) ncbi
Novus Biologicals
mouse monoclonal (ESEE122)
  • immunohistochemistry - paraffin section; human; loading ...; fig 10a
  • western blot; human; loading ...; fig 9c
Novus Biologicals HIF1A antibody (Novus Biologics, NB100-131) was used in immunohistochemistry - paraffin section on human samples (fig 10a) and in western blot on human samples (fig 9c). J Clin Invest (2018) ncbi
mouse monoclonal (H1alpha67)
  • immunohistochemistry; mouse; 1:500; loading ...; fig 5e
Novus Biologicals HIF1A antibody (Novus Biologicals, NB100-105) was used in immunohistochemistry on mouse samples at 1:500 (fig 5e). Nature (2018) ncbi
mouse monoclonal (H1alpha67)
  • western blot; mouse; loading ...; fig 2f
Novus Biologicals HIF1A antibody (Novus, NB100-105SS) was used in western blot on mouse samples (fig 2f). Science (2018) ncbi
mouse monoclonal (H1alpha67)
  • immunohistochemistry - paraffin section; human; loading ...; fig 1c
  • western blot; human; 1:600; loading ...; fig 5f
Novus Biologicals HIF1A antibody (Novus Biologicals, NB100-105) was used in immunohistochemistry - paraffin section on human samples (fig 1c) and in western blot on human samples at 1:600 (fig 5f). J Cell Mol Med (2017) ncbi
mouse monoclonal (H1alpha67)
  • western blot; mouse; loading ...; fig s2a
Novus Biologicals HIF1A antibody (Novus Biologicals, NB100-105) was used in western blot on mouse samples (fig s2a). elife (2017) ncbi
mouse monoclonal (H1alpha67)
  • immunohistochemistry - paraffin section; mouse; loading ...; fig 5c
Novus Biologicals HIF1A antibody (Novus, NB100-105) was used in immunohistochemistry - paraffin section on mouse samples (fig 5c). Cancer Res (2017) ncbi
mouse monoclonal (H1alpha67)
  • immunohistochemistry; mouse; 1:500; loading ...; fig s3a
Novus Biologicals HIF1A antibody (Novus Biologicals, NB100-105) was used in immunohistochemistry on mouse samples at 1:500 (fig s3a). Science (2017) ncbi
mouse monoclonal (H1alpha67)
  • western blot knockout validation; mouse; loading ...; fig 2f
Novus Biologicals HIF1A antibody (Novus, NB100-123) was used in western blot knockout validation on mouse samples (fig 2f). Nat Commun (2016) ncbi
mouse monoclonal (H1alpha67)
  • immunocytochemistry; human; 1:50; loading ...; fig s4a
  • western blot; human; 1:500; loading ...; fig s6
In order to elucidate tumor-derived factors and genetic changes in endothelial cells that contribute to excess centrosomes in tumor endothelial cells, Novus Biologicals HIF1A antibody (Novus, NB100-105) was used in immunocytochemistry on human samples at 1:50 (fig s4a) and in western blot on human samples at 1:500 (fig s6). PLoS ONE (2016) ncbi
mouse monoclonal (H1alpha67)
  • immunoprecipitation; rat; fig 4a
  • western blot; rat; fig 2d
Novus Biologicals HIF1A antibody (Novus, NB100-105) was used in immunoprecipitation on rat samples (fig 4a) and in western blot on rat samples (fig 2d). Am J Transl Res (2016) ncbi
mouse monoclonal (H1alpha67)
  • immunohistochemistry; mouse; 1:500; loading ...; fig e4a
  • western blot; mouse; 1 mg/ml; loading ...; fig 2b
Novus Biologicals HIF1A antibody (Novus, NB100-105) was used in immunohistochemistry on mouse samples at 1:500 (fig e4a) and in western blot on mouse samples at 1 mg/ml (fig 2b). Nature (2016) ncbi
mouse monoclonal (H1alpha67)
  • immunohistochemistry - paraffin section; human; 1:50; fig 1
Novus Biologicals HIF1A antibody (Novus Biologicals, NB100-105) was used in immunohistochemistry - paraffin section on human samples at 1:50 (fig 1). Mol Clin Oncol (2016) ncbi
mouse monoclonal (H1alpha67)
  • immunocytochemistry; mouse; 1:100; fig 1
  • western blot; mouse; 1:500; fig 5
Novus Biologicals HIF1A antibody (Novus Biologicals, H1alpha67) was used in immunocytochemistry on mouse samples at 1:100 (fig 1) and in western blot on mouse samples at 1:500 (fig 5). Sci Rep (2016) ncbi
mouse monoclonal (H1alpha67)
  • immunohistochemistry; human; fig 1B
  • western blot; human; 1:500; fig 1B
Novus Biologicals HIF1A antibody (Novus, NB100-105) was used in immunohistochemistry on human samples (fig 1B) and in western blot on human samples at 1:500 (fig 1B). Front Pharmacol (2016) ncbi
mouse monoclonal (H1alpha67)
  • immunohistochemistry - paraffin section; human; 1:100; loading ...; fig 1a
Novus Biologicals HIF1A antibody (Novus Biologicals, NB100-105) was used in immunohistochemistry - paraffin section on human samples at 1:100 (fig 1a). Nat Commun (2016) ncbi
mouse monoclonal (H1alpha67)
  • immunohistochemistry - paraffin section; mouse; 1:100; fig 4
Novus Biologicals HIF1A antibody (Novus, NB100-105) was used in immunohistochemistry - paraffin section on mouse samples at 1:100 (fig 4). Theranostics (2016) ncbi
mouse monoclonal (H1alpha67)
  • immunohistochemistry; mouse; loading ...; fig 1b
In order to investigate the role of Vhl, Trp53 and Kif3a in renal integrity, Novus Biologicals HIF1A antibody (Novus, NB100-105) was used in immunohistochemistry on mouse samples (fig 1b). J Pathol (2016) ncbi
mouse monoclonal (H1alpha67)
  • western blot; human; loading ...; fig 2b
Novus Biologicals HIF1A antibody (Novus Biologicals, NB100-105) was used in western blot on human samples (fig 2b). Oncol Lett (2016) ncbi
mouse monoclonal (H1alpha67)
  • immunohistochemistry; human; fig 4
Novus Biologicals HIF1A antibody (Novus, NB100-105) was used in immunohistochemistry on human samples (fig 4). Oncotarget (2016) ncbi
mouse monoclonal (H1alpha67)
  • western blot knockout validation; mouse; fig 3
  • western blot; human; fig 3
Novus Biologicals HIF1A antibody (Novus Biologicals, NB100-105) was used in western blot knockout validation on mouse samples (fig 3) and in western blot on human samples (fig 3). Sci Rep (2016) ncbi
mouse monoclonal (H1alpha67)
  • western blot; human; 1:500; fig 3
Novus Biologicals HIF1A antibody (Novus Biologicals, NB100-105) was used in western blot on human samples at 1:500 (fig 3). J Cell Sci (2016) ncbi
mouse monoclonal (H1alpha67)
  • western blot; human; 1:500; fig 3a
Novus Biologicals HIF1A antibody (Novus Biologicals, NB100-105) was used in western blot on human samples at 1:500 (fig 3a). Cell Tissue Res (2016) ncbi
mouse monoclonal (H1alpha67)
  • western blot; human; 1:500
In order to report the contribution of DYRK1A and DYRK1B in cancer stem cells, Novus Biologicals HIF1A antibody (Novus Biologicals, NB100-105) was used in western blot on human samples at 1:500. Nature (2016) ncbi
mouse monoclonal (H1alpha67)
  • immunohistochemistry; human; 1:100; loading ...; fig 2b
Novus Biologicals HIF1A antibody (Novus Biologicals, NB100-105) was used in immunohistochemistry on human samples at 1:100 (fig 2b). Oncotarget (2016) ncbi
mouse monoclonal (H1alpha67)
  • immunohistochemistry - paraffin section; mouse; 1:200; fig s5
Novus Biologicals HIF1A antibody (Novus, NB100-105) was used in immunohistochemistry - paraffin section on mouse samples at 1:200 (fig s5). Cancer Sci (2016) ncbi
mouse monoclonal (ESEE122)
  • immunohistochemistry - paraffin section; human; fig 2
Novus Biologicals HIF1A antibody (Novus Biologicals, ESEE122) was used in immunohistochemistry - paraffin section on human samples (fig 2). J Cancer (2015) ncbi
mouse monoclonal (H1alpha67)
  • western blot; human; 1:2000
Novus Biologicals HIF1A antibody (Novus, NB100-105) was used in western blot on human samples at 1:2000. Life Sci (2015) ncbi
mouse monoclonal (H1alpha67)
  • ELISA; human; fig s4
Novus Biologicals HIF1A antibody (Novus Biologicals, NB100-105) was used in ELISA on human samples (fig s4). PLoS ONE (2015) ncbi
mouse monoclonal (H1alpha67)
  • immunohistochemistry; mouse
  • western blot; human; 1:500
Novus Biologicals HIF1A antibody (Novus Biologicals, NB100-105) was used in immunohistochemistry on mouse samples and in western blot on human samples at 1:500. Sci Rep (2015) ncbi
mouse monoclonal (H1alpha67)
  • western blot; human; loading ...; fig 3a
Novus Biologicals HIF1A antibody (Novus Biologicals, NB100-105) was used in western blot on human samples (fig 3a). Int J Biol Sci (2015) ncbi
mouse monoclonal (H1alpha67)
  • western blot; human; fig 4c
Novus Biologicals HIF1A antibody (Novus Biologicals, NB100-105) was used in western blot on human samples (fig 4c). Int J Mol Med (2015) ncbi
mouse monoclonal (H1alpha67)
  • western blot; human; fig 1
Novus Biologicals HIF1A antibody (Biologicals, NB100-105) was used in western blot on human samples (fig 1). Nucleic Acids Res (2015) ncbi
mouse monoclonal (H1alpha67)
  • western blot; human; tbl 2
Novus Biologicals HIF1A antibody (Novus Biologicals, NB100-105) was used in western blot on human samples (tbl 2). PLoS ONE (2015) ncbi
mouse monoclonal (ESEE122)
  • immunohistochemistry; human
Novus Biologicals HIF1A antibody (Novus Biologicals, NB100-131) was used in immunohistochemistry on human samples . Acta Neuropathol Commun (2014) ncbi
mouse monoclonal (H1alpha67)
  • western blot; mouse
In order to identify DUBA as a suppressor of IL-17 production in T cells, Novus Biologicals HIF1A antibody (Novus, NB100-105) was used in western blot on mouse samples . Nature (2015) ncbi
mouse monoclonal (H1alpha67)
  • immunohistochemistry - frozen section; rat; 1:200; loading ...; fig s2
Novus Biologicals HIF1A antibody (Novus Biologicals, NB100-105) was used in immunohistochemistry - frozen section on rat samples at 1:200 (fig s2). J Cell Biochem (2015) ncbi
mouse monoclonal (H1alpha67)
  • western blot; mouse; 1:1000
Novus Biologicals HIF1A antibody (Novus Biologicals, NB100-105) was used in western blot on mouse samples at 1:1000. Neuroreport (2014) ncbi
mouse monoclonal (ESEE122)
  • western blot; mouse; 1:2000; fig 2
In order to study vascular endothelial growth factor signaling in mice infected with Plasmodium berghei ANKA, Novus Biologicals HIF1A antibody (Novus Biologicals, NB100-131A1) was used in western blot on mouse samples at 1:2000 (fig 2). Front Immunol (2014) ncbi
mouse monoclonal (H1alpha67)
  • immunocytochemistry; rat; 1:200
Novus Biologicals HIF1A antibody (Novus Biological, NB-100-123) was used in immunocytochemistry on rat samples at 1:200. Acta Neuropathol Commun (2014) ncbi
mouse monoclonal (H1alpha67)
  • immunohistochemistry; human; loading ...; fig 6c
Novus Biologicals HIF1A antibody (Novus, NB100-105) was used in immunohistochemistry on human samples (fig 6c). Nucleic Acids Res (2014) ncbi
mouse monoclonal (H1alpha67)
  • western blot; rat
Novus Biologicals HIF1A antibody (Novus Biologicals, NB100-105) was used in western blot on rat samples . J Biol Chem (2013) ncbi
mouse monoclonal (H1alpha67)
  • western blot; human
Novus Biologicals HIF1A antibody (Novus, NB100-123) was used in western blot on human samples . Cell Cycle (2012) ncbi
mouse monoclonal (H1alpha67)
  • western blot; rat
In order to study the role of low-level laser therapy in neuropathic pain alleviation and recovery from chronic constriction injury, Novus Biologicals HIF1A antibody (Novus Biologicals, NB100-105) was used in western blot on rat samples . J Comp Neurol (2012) ncbi
mouse monoclonal (H1alpha67)
  • immunohistochemistry - paraffin section; human; 1:200
  • immunohistochemistry; human
Novus Biologicals HIF1A antibody (Novus Biologicals, NB 100-105) was used in immunohistochemistry - paraffin section on human samples at 1:200 and in immunohistochemistry on human samples . J Histochem Cytochem (2007) ncbi
Abcam
mouse monoclonal (ESEE122)
  • immunohistochemistry - frozen section; mouse; fig 1d
Abcam HIF1A antibody (Abcam, ab8366) was used in immunohistochemistry - frozen section on mouse samples (fig 1d). J Clin Invest (2018) ncbi
mouse monoclonal (ESEE122)
  • immunohistochemistry - frozen section; human; 1:100; loading ...; fig 7b
Abcam HIF1A antibody (Abcam, ab8366) was used in immunohistochemistry - frozen section on human samples at 1:100 (fig 7b). J Histochem Cytochem (2018) ncbi
mouse monoclonal (mgc3)
  • western blot; human; loading ...; fig 2b
Abcam HIF1A antibody (Abcam, ab16066) was used in western blot on human samples (fig 2b). Tumour Biol (2017) ncbi
mouse monoclonal (mgc3)
  • immunohistochemistry - frozen section; human; 1:200
  • immunocytochemistry; human; 1:200; fig e1a
In order to compare the gene expression in individual cells isolated from human brain organoids, Abcam HIF1A antibody (Abcam, AB16066) was used in immunohistochemistry - frozen section on human samples at 1:200 and in immunocytochemistry on human samples at 1:200 (fig e1a). Nature (2017) ncbi
mouse monoclonal (mgc3)
  • immunocytochemistry; human; fig 1
Abcam HIF1A antibody (abcam, ab16066) was used in immunocytochemistry on human samples (fig 1). BMC Cancer (2016) ncbi
mouse monoclonal (ESEE122)
  • immunohistochemistry - paraffin section; human; 1:250; loading ...; fig 2
In order to test if BiP and CHOP expressions correlate with pre-malignant lesion progression, Abcam HIF1A antibody (Abcam, ab8366) was used in immunohistochemistry - paraffin section on human samples at 1:250 (fig 2). Virchows Arch (2016) ncbi
mouse monoclonal (ESEE122)
  • immunocytochemistry; human; fig 1
Abcam HIF1A antibody (Abcam, ab8366) was used in immunocytochemistry on human samples (fig 1). J Diabetes Res (2016) ncbi
mouse monoclonal (ESEE122)
  • immunohistochemistry - paraffin section; human; loading ...; tbl 4
Abcam HIF1A antibody (Abcam, ESEE122) was used in immunohistochemistry - paraffin section on human samples (tbl 4). Chin J Cancer (2016) ncbi
mouse monoclonal (mgc3)
  • western blot; human; 1:500; fig 3
In order to study oxygen-induced endoplasmic reticulum stress in the lens, Abcam HIF1A antibody (Santa Cruz Biotechnology, ab16066) was used in western blot on human samples at 1:500 (fig 3). Exp Ther Med (2015) ncbi
mouse monoclonal (mgc3)
  • immunohistochemistry - paraffin section; mouse; loading ...; fig 1b
Abcam HIF1A antibody (Abcam, ab16066) was used in immunohistochemistry - paraffin section on mouse samples (fig 1b). PLoS ONE (2015) ncbi
mouse monoclonal (ESEE122)
  • western blot; human; 1:1000; fig 3
In order to discuss the consequences of Diabetes Associated Protein in Insulin-sensitive Tissues overexpression, Abcam HIF1A antibody (Abcam, ab8366) was used in western blot on human samples at 1:1000 (fig 3). PLoS ONE (2015) ncbi
mouse monoclonal (ESEE122)
  • immunohistochemistry; human; 1:500; fig 6c
Abcam HIF1A antibody (Abcam, ab8366) was used in immunohistochemistry on human samples at 1:500 (fig 6c). Oncotarget (2015) ncbi
mouse monoclonal (ESEE122)
  • western blot; rat; 1:1000
Abcam HIF1A antibody (Abcam, ab8366) was used in western blot on rat samples at 1:1000. Cell Signal (2014) ncbi
mouse monoclonal (ESEE122)
  • immunohistochemistry - paraffin section; rat; 1:100
Abcam HIF1A antibody (Abcam, ab8366) was used in immunohistochemistry - paraffin section on rat samples at 1:100. Stem Cells Dev (2014) ncbi
rabbit polyclonal
  • immunohistochemistry - paraffin section; mouse; 1:250
Abcam HIF1A antibody (Abcam, ab114977) was used in immunohistochemistry - paraffin section on mouse samples at 1:250. Cardiovasc Res (2014) ncbi
Invitrogen
mouse monoclonal (mgc3)
  • immunocytochemistry; mouse; 1:200; fig s1a
In order to ask whether PrP+ cTnT+ cells are present in the human heart tissue with myocardial infarction, Invitrogen HIF1A antibody (Pierce, MA1-516) was used in immunocytochemistry on mouse samples at 1:200 (fig s1a). Sci Rep (2017) ncbi
mouse monoclonal (H1alpha67)
  • immunohistochemistry; human; loading ...; fig 1b
In order to define distinct functional subgroups of clear cell renal cell carcinoma based on expression of BAF180, Invitrogen HIF1A antibody (Thermo Fisher Scientific, H1alpha67) was used in immunohistochemistry on human samples (fig 1b). Oncogenesis (2017) ncbi
mouse monoclonal (H1alpha67)
  • immunohistochemistry; pig; 1:1000; loading ...; tbl 1
In order to analyze oxidative stress markers after remote ischemic preconditioning in pig., Invitrogen HIF1A antibody (NeoMarkers, Ab-4) was used in immunohistochemistry on pig samples at 1:1000 (tbl 1). Semin Thorac Cardiovasc Surg (2016) ncbi
mouse monoclonal (mgc3)
  • western blot; human; loading ...; fig 1a
In order to propose that HIF-2-alpha is a negative regulator of estrogen receptor expression in breast cancer, Invitrogen HIF1A antibody (Affinity Bioreagents, mgc3) was used in western blot on human samples (fig 1a). FEBS Lett (2016) ncbi
mouse monoclonal (H1alpha67)
  • western blot; human; 1:1000; fig 1
In order to characterize the association with RASAL1 promoter hypermethylation in human coronary endothelial cells and hypoxia-induced endothelial-mesenchymal transition, Invitrogen HIF1A antibody (Thermo Scientific, MA1-16504) was used in western blot on human samples at 1:1000 (fig 1). FEBS Lett (2016) ncbi
mouse monoclonal (H1alpha67)
  • immunohistochemistry; human; 1:200
Invitrogen HIF1A antibody (LabVision, H1alpha67) was used in immunohistochemistry on human samples at 1:200. Int Urol Nephrol (2015) ncbi
mouse monoclonal (H1alpha67)
  • immunohistochemistry - paraffin section; human; 1:50
In order to correlate 18-F-fluoro-deoxyglucose uptake and aggressive tumor biology in predicting outcome in esophageal cancer, Invitrogen HIF1A antibody (Neomarkers, MS-1164) was used in immunohistochemistry - paraffin section on human samples at 1:50. Ann Surg Oncol (2014) ncbi
mouse monoclonal (mgc3)
  • EMSA; mouse
  • EMSA; rat
In order to study the upregulation of pancreatic beta cell ARAP1 by a functional regulatory DNA variant at a type 2 diabetes locus, Invitrogen HIF1A antibody (Thermo Scientific, MA1-516) was used in EMSA on mouse samples and in EMSA on rat samples . Am J Hum Genet (2014) ncbi
mouse monoclonal (H1alpha67)
  • immunohistochemistry; rat; 1:200
In order to study the role of low-level laser therapy in neuropathic pain alleviation and recovery from chronic constriction injury, Invitrogen HIF1A antibody (Thermo, MS-1164-P0) was used in immunohistochemistry on rat samples at 1:200. J Comp Neurol (2012) ncbi
Active Motif
mouse monoclonal (ESEE122)
  • western blot; human; 1:1000; fig 4
Active Motif HIF1A antibody (Active Motif, 61275) was used in western blot on human samples at 1:1000 (fig 4). Oncotarget (2016) ncbi
SICGEN
goat polyclonal
  • western blot; mouse; 1:1000; fig 1
In order to report that K63 ubiquitination is required for chaperone-mediated autophagy degradation of HIF1A in vitro and in vivo, SICGEN HIF1A antibody (Sicgen, AB0112-200) was used in western blot on mouse samples at 1:1000 (fig 1). Sci Rep (2015) ncbi
EMD Millipore
rabbit polyclonal
  • western blot; human; 1:1000
EMD Millipore HIF1A antibody (Millipore, 07-1585) was used in western blot on human samples at 1:1000. Nat Commun (2015) ncbi
rabbit polyclonal
  • western blot; human; 1:1000; fig 3
EMD Millipore HIF1A antibody (Millipore, 07-1585) was used in western blot on human samples at 1:1000 (fig 3). PLoS ONE (2015) ncbi
Articles Reviewed
  1. Song K, Kim J, Lee Y, Bae H, Lee H, Woo S, et al. Mitochondrial reprogramming via ATP5H loss promotes multimodal cancer therapy resistance. J Clin Invest. 2018;128:4098-4114 pubmed publisher
  2. Wendeln A, Degenhardt K, Kaurani L, Gertig M, Ulas T, Jain G, et al. Innate immune memory in the brain shapes neurological disease hallmarks. Nature. 2018;556:332-338 pubmed publisher
  3. Kornberg M, Bhargava P, Kim P, Putluri V, Snowman A, Putluri N, et al. Dimethyl fumarate targets GAPDH and aerobic glycolysis to modulate immunity. Science. 2018;360:449-453 pubmed publisher
  4. La Porta S, Roth L, Singhal M, Mogler C, Spegg C, Schieb B, et al. Endothelial Tie1-mediated angiogenesis and vascular abnormalization promote tumor progression and metastasis. J Clin Invest. 2018;128:834-845 pubmed publisher
  5. Hira V, Wormer J, Kakar H, Breznik B, van der Swaan B, Hulsbos R, et al. Periarteriolar Glioblastoma Stem Cell Niches Express Bone Marrow Hematopoietic Stem Cell Niche Proteins. J Histochem Cytochem. 2018;66:155-173 pubmed publisher
  6. Ye M, Fang Z, Gu H, Song R, Ye J, Li H, et al. Histone deacetylase 5 promotes the migration and invasion of hepatocellular carcinoma via increasing the transcription of hypoxia-inducible factor-1? under hypoxia condition. Tumour Biol. 2017;39:1010428317705034 pubmed publisher
  7. Li W, Chen C, Zhao X, Ye H, Zhao Y, Fu Z, et al. HIF-2? regulates non-canonical glutamine metabolism via activation of PI3K/mTORC2 pathway in human pancreatic ductal adenocarcinoma. J Cell Mol Med. 2017;21:2896-2908 pubmed publisher
  8. Quadrato G, Nguyen T, Macosko E, Sherwood J, Min Yang S, Berger D, et al. Cell diversity and network dynamics in photosensitive human brain organoids. Nature. 2017;545:48-53 pubmed publisher
  9. An Y, Sun K, Joffin N, Zhang F, Deng Y, Donze O, et al. Angiopoietin-2 in white adipose tissue improves metabolic homeostasis through enhanced angiogenesis. elife. 2017;6: pubmed publisher
  10. Liao L, Song M, Li X, Tang L, Zhang T, Zhang L, et al. E3 Ubiquitin Ligase UBR5 Drives the Growth and Metastasis of Triple-Negative Breast Cancer. Cancer Res. 2017;77:2090-2101 pubmed publisher
  11. Williams P, Harder J, Foxworth N, Cochran K, Philip V, Porciatti V, et al. Vitamin B3 modulates mitochondrial vulnerability and prevents glaucoma in aged mice. Science. 2017;355:756-760 pubmed publisher
  12. Omatsu Kanbe M, Nozuchi N, Nishino Y, Mukaisho K, Sugihara H, Matsuura H. Identification of cardiac progenitors that survive in the ischemic human heart after ventricular myocyte death. Sci Rep. 2017;7:41318 pubmed publisher
  13. Murakami A, Wang L, Kalhorn S, Schraml P, Rathmell W, Tan A, et al. Context-dependent role for chromatin remodeling component PBRM1/BAF180 in clear cell renal cell carcinoma. Oncogenesis. 2017;6:e287 pubmed publisher
  14. Jablonska B, Gierdalski M, Chew L, Hawley T, Catron M, Lichauco A, et al. Sirt1 regulates glial progenitor proliferation and regeneration in white matter after neonatal brain injury. Nat Commun. 2016;7:13866 pubmed publisher
  15. Yu Z, Mouillesseaux K, Kushner E, Bautch V. Tumor-Derived Factors and Reduced p53 Promote Endothelial Cell Centrosome Over-Duplication. PLoS ONE. 2016;11:e0168334 pubmed publisher
  16. Li F, Li Z, Jiang Z, Tian Y, Wang Z, Yi W, et al. Enhancement of early cardiac differentiation of dedifferentiated fat cells by dimethyloxalylglycine via notch signaling pathway. Am J Transl Res. 2016;8:4791-4801 pubmed
  17. Chen W, Hill H, Christie A, Kim M, Holloman E, Pavía Jiménez A, et al. Targeting renal cell carcinoma with a HIF-2 antagonist. Nature. 2016;539:112-117 pubmed publisher
  18. Arvola O, Haapanen H, Herajärvi J, Anttila T, Puistola U, Karihtala P, et al. Remote Ischemic Preconditioning Reduces Cerebral Oxidative Stress Following Hypothermic Circulatory Arrest in a Porcine Model. Semin Thorac Cardiovasc Surg. 2016;28:92-102 pubmed publisher
  19. Takasaki C, Kobayashi M, Ishibashi H, Akashi T, Okubo K. Expression of hypoxia-inducible factor-1? affects tumor proliferation and antiapoptosis in surgically resected lung cancer. Mol Clin Oncol. 2016;5:295-300 pubmed
  20. Phelan J, Reen F, Dunphy N, O CONNOR R, O Gara F. Bile acids destabilise HIF-1? and promote anti-tumour phenotypes in cancer cell models. BMC Cancer. 2016;16:476 pubmed publisher
  21. Schokrpur S, Hu J, Moughon D, Liu P, Lin L, Hermann K, et al. CRISPR-Mediated VHL Knockout Generates an Improved Model for Metastatic Renal Cell Carcinoma. Sci Rep. 2016;6:29032 pubmed publisher
  22. Higashimura Y, Kitakaze T, Harada N, Inui H, Nakano Y, Yamaji R. pVHL-mediated degradation of HIF-2? regulates estrogen receptor ? expression in normoxic breast cancer cells. FEBS Lett. 2016;590:2690-9 pubmed publisher
  23. Maugeri G, D Amico A, Reitano R, Magro G, Cavallaro S, Salomone S, et al. PACAP and VIP Inhibit the Invasiveness of Glioblastoma Cells Exposed to Hypoxia through the Regulation of HIFs and EGFR Expression. Front Pharmacol. 2016;7:139 pubmed publisher
  24. Hoefflin R, Lahrmann B, Warsow G, Hübschmann D, Spath C, Walter B, et al. Spatial niche formation but not malignant progression is a driving force for intratumoural heterogeneity. Nat Commun. 2016;7:ncomms11845 pubmed publisher
  25. Lo Dico A, Costa V, Martelli C, Diceglie C, Rajata F, Rizzo A, et al. MiR675-5p Acts on HIF-1? to Sustain Hypoxic Responses: A New Therapeutic Strategy for Glioma. Theranostics. 2016;6:1105-18 pubmed publisher
  26. Piton N, Wason J, Colasse É, Cornic M, Lemoine F, Le Pessot F, et al. Endoplasmic reticulum stress, unfolded protein response and development of colon adenocarcinoma. Virchows Arch. 2016;469:145-54 pubmed publisher
  27. Guinot A, Lehmann H, Wild P, Frew I. Combined deletion of Vhl, Trp53 and Kif3a causes cystic and neoplastic renal lesions. J Pathol. 2016;239:365-73 pubmed publisher
  28. Xu X, Tan X, Hulshoff M, Wilhelmi T, Zeisberg M, Zeisberg E. Hypoxia-induced endothelial-mesenchymal transition is associated with RASAL1 promoter hypermethylation in human coronary endothelial cells. FEBS Lett. 2016;590:1222-33 pubmed publisher
  29. Park S, Kim J, Kim N, Yang K, Shim J, Heo K. Estradiol, TGF-?1 and hypoxia promote breast cancer stemness and EMT-mediated breast cancer migration. Oncol Lett. 2016;11:1895-1902 pubmed
  30. Ananthula S, Sinha A, El Gassim M, Batth S, Marshall G, Gardner L, et al. Geminin overexpression-dependent recruitment and crosstalk with mesenchymal stem cells enhance aggressiveness in triple negative breast cancers. Oncotarget. 2016;7:20869-89 pubmed publisher
  31. Edalat L, Stegen B, Klumpp L, Haehl E, Schilbach K, Lukowski R, et al. BK K+ channel blockade inhibits radiation-induced migration/brain infiltration of glioblastoma cells. Oncotarget. 2016;7:14259-78 pubmed publisher
  32. Chowdhury H, Velebit J, Radić N, Frančič V, Kreft M, Zorec R. Hypoxia Alters the Expression of Dipeptidyl Peptidase 4 and Induces Developmental Remodeling of Human Preadipocytes. J Diabetes Res. 2016;2016:7481470 pubmed publisher
  33. Adighibe O, Leek R, Fernandez Mercado M, Hu J, Snell C, Gatter K, et al. Why some tumours trigger neovascularisation and others don't: the story thus far. Chin J Cancer. 2016;35:18 pubmed publisher
  34. Mori H, Yao Y, Learman B, Kurozumi K, Ishida J, Ramakrishnan S, et al. Induction of WNT11 by hypoxia and hypoxia-inducible factor-1α regulates cell proliferation, migration and invasion. Sci Rep. 2016;6:21520 pubmed publisher
  35. Chen K, Zeng J, Xiao H, Huang C, Hu J, Yao W, et al. Regulation of glucose metabolism by p62/SQSTM1 through HIF1α. J Cell Sci. 2016;129:817-30 pubmed publisher
  36. Maugeri G, D Amico A, Reitano R, Saccone S, Federico C, Cavallaro S, et al. Parkin modulates expression of HIF-1α and HIF-3α during hypoxia in gliobastoma-derived cell lines in vitro. Cell Tissue Res. 2016;364:465-474 pubmed publisher
  37. Lee S, Frattini V, Bansal M, Castano A, Sherman D, Hutchinson K, et al. An ID2-dependent mechanism for VHL inactivation in cancer. Nature. 2016;529:172-7 pubmed publisher
  38. Sharpe M, Baskin D. Monoamine oxidase B levels are highly expressed in human gliomas and are correlated with the expression of HiF-1α and with transcription factors Sp1 and Sp3. Oncotarget. 2016;7:3379-93 pubmed publisher
  39. Yamano S, Gi M, Tago Y, Doi K, Okada S, Hirayama Y, et al. Role of deltaNp63(pos)CD44v(pos) cells in the development of N-nitroso-tris-chloroethylurea-induced peripheral-type mouse lung squamous cell carcinomas. Cancer Sci. 2016;107:123-32 pubmed publisher
  40. Zheng X, Xu J, Chen X, Li W, Wang T. Attenuation of oxygen fluctuation-induced endoplasmic reticulum stress in human lens epithelial cells. Exp Ther Med. 2015;10:1883-1887 pubmed
  41. Singh S, Chand H, Gundavarapu S, Saeed A, Langley R, Tesfaigzi Y, et al. HIF-1α Plays a Critical Role in the Gestational Sidestream Smoke-Induced Bronchopulmonary Dysplasia in Mice. PLoS ONE. 2015;10:e0137757 pubmed publisher
  42. Ochi F, Shiozaki A, Ichikawa D, Fujiwara H, Nakashima S, Takemoto K, et al. Carbonic Anhydrase XII as an Independent Prognostic Factor in Advanced Esophageal Squamous Cell Carcinoma. J Cancer. 2015;6:922-9 pubmed publisher
  43. Lin A, Abbas S, Kim S, Ortega M, Bouamar H, Escobedo Y, et al. D2HGDH regulates alpha-ketoglutarate levels and dioxygenase function by modulating IDH2. Nat Commun. 2015;6:7768 pubmed publisher
  44. Wang I, Sun K, Tsai T, Chen C, Chang S, Yu T, et al. MiR-20a-5p mediates hypoxia-induced autophagy by targeting ATG16L1 in ischemic kidney injury. Life Sci. 2015;136:133-41 pubmed publisher
  45. Kontro H, Cannino G, Rustin P, Dufour E, Kainulainen H. DAPIT Over-Expression Modulates Glucose Metabolism and Cell Behaviour in HEK293T Cells. PLoS ONE. 2015;10:e0131990 pubmed publisher
  46. Chan M, Atasoylu O, Hodson E, Tumber A, Leung I, Chowdhury R, et al. Potent and Selective Triazole-Based Inhibitors of the Hypoxia-Inducible Factor Prolyl-Hydroxylases with Activity in the Murine Brain. PLoS ONE. 2015;10:e0132004 pubmed publisher
  47. Espana Agusti J, Tuveson D, Adams D, Matakidou A. A minimally invasive, lentiviral based method for the rapid and sustained genetic manipulation of renal tubules. Sci Rep. 2015;5:11061 pubmed publisher
  48. Sun L, Xu C, Chen G, Yu M, Yang S, Qiu Y, et al. A Novel Role of OS-9 in the Maintenance of Intestinal Barrier Function from Hypoxia-induced Injury via p38-dependent Pathway. Int J Biol Sci. 2015;11:664-71 pubmed publisher
  49. Ferreira J, Soares A, Ramalho J, Pereira P, Girao H. K63 linked ubiquitin chain formation is a signal for HIF1A degradation by Chaperone-Mediated Autophagy. Sci Rep. 2015;5:10210 pubmed publisher
  50. Park H, Lee D, Yim M, Choi Y, Park S, Seo S, et al. 3,3'-Diindolylmethane inhibits VEGF expression through the HIF-1α and NF-κB pathways in human retinal pigment epithelial cells under chemical hypoxic conditions. Int J Mol Med. 2015;36:301-8 pubmed publisher
  51. Bánfi G, Teleki I, Nyirády P, Keszthelyi A, Romics I, Fintha A, et al. Changes of protein expression in prostate cancer having lost its androgen sensitivity. Int Urol Nephrol. 2015;47:1149-54 pubmed publisher
  52. Sadowski S, Boufraqech M, Zhang L, Mehta A, Kapur P, Zhang Y, et al. Torin2 targets dysregulated pathways in anaplastic thyroid cancer and inhibits tumor growth and metastasis. Oncotarget. 2015;6:18038-49 pubmed
  53. Liu X, Chen Z, Xu C, Leng X, Cao H, Ouyang G, et al. Repression of hypoxia-inducible factor α signaling by Set7-mediated methylation. Nucleic Acids Res. 2015;43:5081-98 pubmed publisher
  54. Chan N, He S, Spee C, Ishikawa K, Hinton D. Attenuation of choroidal neovascularization by histone deacetylase inhibitor. PLoS ONE. 2015;10:e0120587 pubmed publisher
  55. Shankar G, Taylor Weiner A, Lelic N, Jones R, Kim J, FRANCIS J, et al. Sporadic hemangioblastomas are characterized by cryptic VHL inactivation. Acta Neuropathol Commun. 2014;2:167 pubmed publisher
  56. Rutz S, Kayagaki N, Phung Q, Eidenschenk C, Noubade R, Wang X, et al. Deubiquitinase DUBA is a post-translational brake on interleukin-17 production in T cells. Nature. 2015;518:417-21 pubmed publisher
  57. Lee H, Kim K, Lim H, Choi M, Kim H, Ahn H, et al. Priming Wharton's jelly-derived mesenchymal stromal/stem cells with ROCK inhibitor improves recovery in an intracerebral hemorrhage model. J Cell Biochem. 2015;116:310-9 pubmed publisher
  58. Huang T, Huang W, Zhang Z, Yu L, Xie C, Zhu D, et al. Hypoxia-inducible factor-1? upregulation in microglia following hypoxia protects against ischemia-induced cerebral infarction. Neuroreport. 2014;25:1122-8 pubmed publisher
  59. Hempel C, Hoyer N, Kildemoes A, Jendresen C, Kurtzhals J. Systemic and Cerebral Vascular Endothelial Growth Factor Levels Increase in Murine Cerebral Malaria along with Increased Calpain and Caspase Activity and Can be Reduced by Erythropoietin Treatment. Front Immunol. 2014;5:291 pubmed publisher
  60. Schreurs L, Smit J, Pavlov K, Pultrum B, Pruim J, Groen H, et al. Prognostic impact of clinicopathological features and expression of biomarkers related to (18)F-FDG uptake in esophageal cancer. Ann Surg Oncol. 2014;21:3751-7 pubmed publisher
  61. Ramamoorthy P, Shi H. Ischemia induces different levels of hypoxia inducible factor-1? protein expression in interneurons and pyramidal neurons. Acta Neuropathol Commun. 2014;2:51 pubmed publisher
  62. Waza A, Andrabi K, Hussain M. Protein kinase C (PKC) mediated interaction between conexin43 (Cx43) and K(+)(ATP) channel subunit (Kir6.1) in cardiomyocyte mitochondria: Implications in cytoprotection against hypoxia induced cell apoptosis. Cell Signal. 2014;26:1909-17 pubmed publisher
  63. Kulzer J, Stitzel M, Morken M, Huyghe J, Fuchsberger C, Kuusisto J, et al. A common functional regulatory variant at a type 2 diabetes locus upregulates ARAP1 expression in the pancreatic beta cell. Am J Hum Genet. 2014;94:186-97 pubmed publisher
  64. Chen T, Shih Y, Tseng J, Lai M, Wu C, Li Y, et al. Overexpression of FGF9 in colon cancer cells is mediated by hypoxia-induced translational activation. Nucleic Acids Res. 2014;42:2932-44 pubmed publisher
  65. Ding H, Gao Y, Wang Y, Hu C, Sun Y, Zhang C. Dimethyloxaloylglycine increases the bone healing capacity of adipose-derived stem cells by promoting osteogenic differentiation and angiogenic potential. Stem Cells Dev. 2014;23:990-1000 pubmed publisher
  66. Ronkainen V, Tuomainen T, Huusko J, Laidinen S, Malinen M, Palvimo J, et al. Hypoxia-inducible factor 1-induced G protein-coupled receptor 35 expression is an early marker of progressive cardiac remodelling. Cardiovasc Res. 2014;101:69-77 pubmed publisher
  67. Xie L, Collins J. Transcription factors Sp1 and Hif2α mediate induction of the copper-transporting ATPase (Atp7a) gene in intestinal epithelial cells during hypoxia. J Biol Chem. 2013;288:23943-52 pubmed publisher
  68. Salem A, Howell A, Sartini M, Sotgia F, Lisanti M. Downregulation of stromal BRCA1 drives breast cancer tumor growth via upregulation of HIF-1?, autophagy and ketone body production. Cell Cycle. 2012;11:4167-73 pubmed publisher
  69. Hsieh Y, Chou L, Chang P, Yang C, Kao M, Hong C. Low-level laser therapy alleviates neuropathic pain and promotes function recovery in rats with chronic constriction injury: possible involvements in hypoxia-inducible factor 1? (HIF-1?). J Comp Neurol. 2012;520:2903-16 pubmed publisher
  70. Groenman F, Rutter M, Caniggia I, Tibboel D, Post M. Hypoxia-inducible factors in the first trimester human lung. J Histochem Cytochem. 2007;55:355-63 pubmed