This is a Validated Antibody Database (VAD) review about cow GJA1, based on 33 published articles (read how Labome selects the articles), using GJA1 antibody in all methods. It is aimed to help Labome visitors find the most suited GJA1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
GJA1 synonym: gap junction alpha-1 protein; connexin-43; cx43; gap junction protein, alpha 1, 43 kD (connexin 43); gap junction protein, alpha 1, 43kDa; vascular smooth muscle connexin-43

Abcam
rabbit polyclonal
  • immunohistochemistry; human; 1:1000; loading ...; fig 4c
Abcam GJA1 antibody (Abcam, ab11370) was used in immunohistochemistry on human samples at 1:1000 (fig 4c). Nat Commun (2018) ncbi
rabbit polyclonal
  • western blot; mouse; loading ...; fig 5a
In order to examine the role of the E2F pathway in cardiac metabolism, Abcam GJA1 antibody (Abcam, ab11370) was used in western blot on mouse samples (fig 5a). PLoS ONE (2017) ncbi
rabbit polyclonal
  • immunohistochemistry - paraffin section; mouse; loading ...; fig 5b
In order to show that decreased WNT/beta-catenin contributes to the pathophysiology of lamin A/C gene cardiomyopathy, Abcam GJA1 antibody (Abcam, ab11370) was used in immunohistochemistry - paraffin section on mouse samples (fig 5b). Hum Mol Genet (2017) ncbi
rabbit polyclonal
  • immunohistochemistry - paraffin section; rat; 1:200; fig 9a
  • western blot; rat; 1:3000; fig 9g
In order to elucidate how particulate matter impairs male reproduction, Abcam GJA1 antibody (Abcam, ab11370) was used in immunohistochemistry - paraffin section on rat samples at 1:200 (fig 9a) and in western blot on rat samples at 1:3000 (fig 9g). Toxicol Lett (2017) ncbi
mouse monoclonal (CXN-6)
  • western blot; rabbit; 1:1500; fig 8
Abcam GJA1 antibody (abcam, 11369) was used in western blot on rabbit samples at 1:1500 (fig 8). Mol Med Rep (2016) ncbi
rabbit polyclonal
  • immunohistochemistry - frozen section; rat; 1:700; fig 1
Abcam GJA1 antibody (Abcam, ab11370) was used in immunohistochemistry - frozen section on rat samples at 1:700 (fig 1). Front Pharmacol (2016) ncbi
rabbit polyclonal
  • immunocytochemistry; human; 1:500; fig 1
In order to determine the autonomouse beating rate adaptation in cardiomyocytes from human stem cells, Abcam GJA1 antibody (Abcam, ab11370) was used in immunocytochemistry on human samples at 1:500 (fig 1). Nat Commun (2016) ncbi
rabbit polyclonal
  • immunocytochemistry; rat; 1:500; fig s4
  • western blot; rat; 1:5000; fig 6a
Abcam GJA1 antibody (Abcam, ab11370) was used in immunocytochemistry on rat samples at 1:500 (fig s4) and in western blot on rat samples at 1:5000 (fig 6a). PLoS ONE (2015) ncbi
rabbit polyclonal
  • immunocytochemistry; human; 1:200; fig 2
Abcam GJA1 antibody (Abcam, Ab11370) was used in immunocytochemistry on human samples at 1:200 (fig 2). PLoS ONE (2015) ncbi
rabbit polyclonal
  • western blot; mouse; 1:5000
Abcam GJA1 antibody (Abcam, ab11370) was used in western blot on mouse samples at 1:5000. J Mol Cell Cardiol (2015) ncbi
rabbit polyclonal
  • immunocytochemistry; mouse; 1:200; fig 2
In order to identify sodium nitroprusside as a molecules that efficiently promotes the generation of cardiac cells, Abcam GJA1 antibody (Abcam, ab11370) was used in immunocytochemistry on mouse samples at 1:200 (fig 2). Stem Cell Reports (2015) ncbi
rabbit polyclonal
  • immunocytochemistry; mouse; 1:100; fig 6d
Abcam GJA1 antibody (Abcam, ab11370) was used in immunocytochemistry on mouse samples at 1:100 (fig 6d). Reprod Sci (2015) ncbi
rabbit polyclonal
  • immunohistochemistry - paraffin section; mouse; 1:100; fig s12b
Abcam GJA1 antibody (Abcam, ab11370) was used in immunohistochemistry - paraffin section on mouse samples at 1:100 (fig s12b). Nat Commun (2015) ncbi
rabbit polyclonal
  • immunocytochemistry; human
Abcam GJA1 antibody (Abcam, ab11370) was used in immunocytochemistry on human samples . Int J Nanomedicine (2015) ncbi
rabbit polyclonal
  • immunocytochemistry; human; 1:100
Abcam GJA1 antibody (Abcam, ab11370) was used in immunocytochemistry on human samples at 1:100. Macromol Biosci (2015) ncbi
mouse monoclonal (CXN-6)
  • immunohistochemistry; human; 1:100; fig 6
In order to determine how cardiomyocyte differentiation from human muscle derived stem cells due to combined soluble and biophysical factor modulation, Abcam GJA1 antibody (Abcam, ab11369) was used in immunohistochemistry on human samples at 1:100 (fig 6). Sci Rep (2014) ncbi
rabbit polyclonal
  • immunohistochemistry - frozen section; rat; 1:50
Abcam GJA1 antibody (Abcam, ab11370) was used in immunohistochemistry - frozen section on rat samples at 1:50. Physiol Rep (2014) ncbi
rabbit polyclonal
  • immunohistochemistry - paraffin section; Rhesus monkey; 1:5000
In order to examine the localization of epithelial junctions in relation to paracellular permeability and intestinal adhesion, Abcam GJA1 antibody (Abcam, Ab11370) was used in immunohistochemistry - paraffin section on Rhesus monkey samples at 1:5000. Exp Toxicol Pathol (2014) ncbi
rabbit polyclonal
  • western blot; mouse; 1:1000
Abcam GJA1 antibody (Abcam, ab11370) was used in western blot on mouse samples at 1:1000. PLoS ONE (2014) ncbi
rabbit polyclonal
  • western blot; mouse
Abcam GJA1 antibody (Abcam, ab11370) was used in western blot on mouse samples . PLoS ONE (2014) ncbi
rabbit polyclonal
  • western blot; mouse; 1:6000
Abcam GJA1 antibody (Abcam, ab11370) was used in western blot on mouse samples at 1:6000. Stem Cells Dev (2013) ncbi
Santa Cruz Biotechnology
mouse monoclonal (CXN-6)
  • western blot; mouse; 1:1000; fig 3
In order to study the alteration of the morphological characteristics of astrocytes in the dentate gyrus by hippocampus-based contextual memory, Santa Cruz Biotechnology GJA1 antibody (Santa Cruz, sc-59949) was used in western blot on mouse samples at 1:1000 (fig 3). Mol Brain (2016) ncbi
mouse monoclonal (CXN-6)
  • immunocytochemistry; human; 1:25
Santa Cruz Biotechnology GJA1 antibody (Santa Cruz, sc-59949) was used in immunocytochemistry on human samples at 1:25. Cell Tissue Res (2013) ncbi
MilliporeSigma
mouse monoclonal (CXN-6)
  • immunocytochemistry; chicken; fig 1
MilliporeSigma GJA1 antibody (Sigma-Aldrich, C8093) was used in immunocytochemistry on chicken samples (fig 1). Mol Biol Cell (2017) ncbi
mouse monoclonal (CXN-6)
  • western blot; rat; 1:500; loading ...; fig 2b
In order to evaluate if Ezrin associates with connexin 43 in cell types that form stable gap junctions and serve as an A kinase anchoring protein, MilliporeSigma GJA1 antibody (Sigma, C8093) was used in western blot on rat samples at 1:500 (fig 2b). Cell Signal (2017) ncbi
mouse monoclonal (CXN-6)
  • immunohistochemistry - paraffin section; human; 1:800; fig 4
In order to study a reduction in claudin-11 at the sertoli cell tight junction by gonadotropin suppression in men, MilliporeSigma GJA1 antibody (Sigma, C8093) was used in immunohistochemistry - paraffin section on human samples at 1:800 (fig 4). Hum Reprod (2016) ncbi
mouse monoclonal (CXN-6)
  • western blot; mouse; 1:100; tbl 1
In order to elucidate a deletion of AMP-activated protein kinase in mouse Sertoli cells that modify germ cell quality, MilliporeSigma GJA1 antibody (Sigma, CXN-6) was used in western blot on mouse samples at 1:100 (tbl 1). Mol Cell Endocrinol (2016) ncbi
mouse monoclonal (CXN-6)
  • immunohistochemistry - frozen section; mouse; 1:500; fig 1
  • western blot; mouse; 1:8000; fig 1
  • immunohistochemistry; human; 1:500; fig 2
  • western blot; human; 1:8000; fig 2
MilliporeSigma GJA1 antibody (Sigma, C8093) was used in immunohistochemistry - frozen section on mouse samples at 1:500 (fig 1), in western blot on mouse samples at 1:8000 (fig 1), in immunohistochemistry on human samples at 1:500 (fig 2) and in western blot on human samples at 1:8000 (fig 2). Sci Rep (2015) ncbi
mouse monoclonal (CXN-6)
  • immunohistochemistry; mouse; 1:50
MilliporeSigma GJA1 antibody (Sigma-Aldrich, C8093) was used in immunohistochemistry on mouse samples at 1:50. Endocrinology (2015) ncbi
mouse monoclonal (CXN-6)
  • immunocytochemistry; chicken; 1:200
In order to study the role of gap junctional coupling in epithelial repair in the avian cochlea, MilliporeSigma GJA1 antibody (Sigma-Aldrich, C8093) was used in immunocytochemistry on chicken samples at 1:200. J Neurosci (2014) ncbi
mouse monoclonal (CXN-6)
  • immunocytochemistry; rat
MilliporeSigma GJA1 antibody (Sigma, C8093) was used in immunocytochemistry on rat samples . Carcinogenesis (2014) ncbi
EMD Millipore
rabbit polyclonal
  • immunohistochemistry - frozen section; rat; 1:200; loading ...; fig 3a
In order to suggest that ectopic beats originating in the myocardial sleeves of the pulmonary veins occur only under pathological conditions, EMD Millipore GJA1 antibody (Chemicon, AB1727) was used in immunohistochemistry - frozen section on rat samples at 1:200 (fig 3a). Exp Ther Med (2016) ncbi
rabbit polyclonal
  • immunohistochemistry - paraffin section; mouse
  • western blot; mouse; 1:2000
EMD Millipore GJA1 antibody (Millipore, AB1727) was used in immunohistochemistry - paraffin section on mouse samples and in western blot on mouse samples at 1:2000. Circ Arrhythm Electrophysiol (2015) ncbi
Articles Reviewed
  1. Anderson D, Kaplan D, Bell K, Koutsis K, Haynes J, Mills R, et al. NKX2-5 regulates human cardiomyogenesis via a HEY2 dependent transcriptional network. Nat Commun. 2018;9:1373 pubmed publisher
  2. Boswell B, Korol A, West Mays J, Musil L. Dual function of TGF? in lens epithelial cell fate: implications for secondary cataract. Mol Biol Cell. 2017;28:907-921 pubmed publisher
  3. Major J, Dewan A, Salih M, Leddy J, Tuana B. E2F6 Impairs Glycolysis and Activates BDH1 Expression Prior to Dilated Cardiomyopathy. PLoS ONE. 2017;12:e0170066 pubmed publisher
  4. Dukic A, Haugen L, Pidoux G, Leithe E, Bakke O, Tasken K. A protein kinase A-ezrin complex regulates connexin 43 gap junction communication in liver epithelial cells. Cell Signal. 2017;32:1-11 pubmed publisher
  5. Le Dour C, Macquart C, Sera F, Homma S, Bonne G, Morrow J, et al. Decreased WNT/?-catenin signalling contributes to the pathogenesis of dilated cardiomyopathy caused by mutations in the lamin a/C gene. Hum Mol Genet. 2017;26:333-343 pubmed publisher
  6. Cao X, Shen L, Wu S, Yan C, Zhou Y, Xiong G, et al. Urban fine particulate matter exposure causes male reproductive injury through destroying blood-testis barrier (BTB) integrity. Toxicol Lett. 2017;266:1-12 pubmed publisher
  7. Xiao Y, Cai X, Atkinson A, Logantha S, Boyett M, Dobrzynski H. Expression of connexin 43, ion channels and Ca2+-handling proteins in rat pulmonary vein cardiomyocytes. Exp Ther Med. 2016;12:3233-3241 pubmed
  8. Choi M, Ahn S, Yang E, Kim H, Chong Y, Kim H. Hippocampus-based contextual memory alters the morphological characteristics of astrocytes in the dentate gyrus. Mol Brain. 2016;9:72 pubmed publisher
  9. Wang Y, Li Y, Song L, Li Y, Jiang S, Zhang S. The transplantation of Akt-overexpressing amniotic fluid-derived mesenchymal stem cells protects the heart against ischemia-reperfusion injury in rabbits. Mol Med Rep. 2016;14:234-42 pubmed publisher
  10. Bragança B, Oliveira Monteiro N, Ferreirinha F, Lima P, Faria M, Fontes Sousa A, et al. Ion Fluxes through KCa2 (SK) and Cav1 (L-type) Channels Contribute to Chronoselectivity of Adenosine A1 Receptor-Mediated Actions in Spontaneously Beating Rat Atria. Front Pharmacol. 2016;7:45 pubmed publisher
  11. McCabe M, Tarulli G, Laven Law G, Matthiesson K, Meachem S, McLachlan R, et al. Gonadotropin suppression in men leads to a reduction in claudin-11 at the Sertoli cell tight junction. Hum Reprod. 2016;31:875-86 pubmed publisher
  12. Eng G, Lee B, Protas L, Gagliardi M, Brown K, Kass R, et al. Autonomous beating rate adaptation in human stem cell-derived cardiomyocytes. Nat Commun. 2016;7:10312 pubmed publisher
  13. Bertoldo M, Guibert E, Faure M, Guillou F, Ramé C, Nadal Desbarats L, et al. Specific deletion of AMP-activated protein kinase (α1AMPK) in mouse Sertoli cells modifies germ cell quality. Mol Cell Endocrinol. 2016;423:96-112 pubmed publisher
  14. Müller A, Stellmacher A, Freitag C, Landgraf P, Dieterich D. Monitoring Astrocytic Proteome Dynamics by Cell Type-Specific Protein Labeling. PLoS ONE. 2015;10:e0145451 pubmed publisher
  15. Oltolina F, Zamperone A, Colangelo D, Gregoletto L, Reano S, Pietronave S, et al. Human Cardiac Progenitor Spheroids Exhibit Enhanced Engraftment Potential. PLoS ONE. 2015;10:e0137999 pubmed publisher
  16. Gonzalez J, Ramachandran J, Xie L, Contreras J, Fraidenraich D. Selective Connexin43 Inhibition Prevents Isoproterenol-Induced Arrhythmias and Lethality in Muscular Dystrophy Mice. Sci Rep. 2015;5:13490 pubmed publisher
  17. Meraviglia V, Azzimato V, Colussi C, Florio M, Binda A, Panariti A, et al. Acetylation mediates Cx43 reduction caused by electrical stimulation. J Mol Cell Cardiol. 2015;87:54-64 pubmed publisher
  18. Quang K, Maguy A, Qi X, Naud P, Xiong F, Tadevosyan A, et al. Loss of cardiomyocyte integrin-linked kinase produces an arrhythmogenic cardiomyopathy in mice. Circ Arrhythm Electrophysiol. 2015;8:921-32 pubmed publisher
  19. Tsai S, Maass K, Lu J, Fishman G, Chen S, Evans T. Efficient Generation of Cardiac Purkinje Cells from ESCs by Activating cAMP Signaling. Stem Cell Reports. 2015;4:1089-102 pubmed publisher
  20. Sriraman K, Bhartiya D, Anand S, Bhutda S. Mouse Ovarian Very Small Embryonic-Like Stem Cells Resist Chemotherapy and Retain Ability to Initiate Oocyte-Specific Differentiation. Reprod Sci. 2015;22:884-903 pubmed publisher
  21. Aschar Sobbi R, Izaddoustdar F, Korogyi A, Wang Q, Farman G, Yang F, et al. Increased atrial arrhythmia susceptibility induced by intense endurance exercise in mice requires TNFα. Nat Commun. 2015;6:6018 pubmed publisher
  22. Kim S, Ebbert K, Cordeiro M, Romero M, Zhu J, Serna V, et al. Cell autonomous phosphoinositide 3-kinase activation in oocytes disrupts normal ovarian function through promoting survival and overgrowth of ovarian follicles. Endocrinology. 2015;156:1464-76 pubmed publisher
  23. Asiri A, Marwani H, Khan S, Webster T. Understanding greater cardiomyocyte functions on aligned compared to random carbon nanofibers in PLGA. Int J Nanomedicine. 2015;10:89-96 pubmed publisher
  24. Jagger D, Nickel R, Forge A. Gap junctional coupling is essential for epithelial repair in the avian cochlea. J Neurosci. 2014;34:15851-60 pubmed publisher
  25. Chen Y, Wang J, Shen B, Chan C, Wang C, Zhao Y, et al. Engineering a freestanding biomimetic cardiac patch using biodegradable poly(lactic-co-glycolic acid) (PLGA) and human embryonic stem cell-derived ventricular cardiomyocytes (hESC-VCMs). Macromol Biosci. 2015;15:426-36 pubmed publisher
  26. Tchao J, Han L, Lin B, Yang L, Tobita K. Combined biophysical and soluble factor modulation induces cardiomyocyte differentiation from human muscle derived stem cells. Sci Rep. 2014;4:6614 pubmed publisher
  27. Zogbi C, Saturi de Carvalho A, Nakamuta J, Caceres V, Prando S, Giorgi M, et al. Early postnatal rat ventricle resection leads to long-term preserved cardiac function despite tissue hypoperfusion. Physiol Rep. 2014;2: pubmed publisher
  28. Gumber S, Nusrat A, Villinger F. Immunohistological characterization of intercellular junction proteins in rhesus macaque intestine. Exp Toxicol Pathol. 2014;66:437-44 pubmed publisher
  29. Swärd K, Albinsson S, Rippe C. Arterial dysfunction but maintained systemic blood pressure in cavin-1-deficient mice. PLoS ONE. 2014;9:e92428 pubmed publisher
  30. Uzer G, Pongkitwitoon S, Ian C, Thompson W, Rubin J, Chan M, et al. Gap junctional communication in osteocytes is amplified by low intensity vibrations in vitro. PLoS ONE. 2014;9:e90840 pubmed publisher
  31. Ryszawy D, Sarna M, Rak M, Szpak K, Kedracka Krok S, Michalik M, et al. Functional links between Snail-1 and Cx43 account for the recruitment of Cx43-positive cells into the invasive front of prostate cancer. Carcinogenesis. 2014;35:1920-30 pubmed publisher
  32. Behrens A, Iacovino M, Lohr J, Ren Y, Zierold C, Harvey R, et al. Nkx2-5 mediates differential cardiac differentiation through interaction with Hoxa10. Stem Cells Dev. 2013;22:2211-20 pubmed publisher
  33. Fong G, Backman L, Andersson G, Scott A, Danielson P. Human tenocytes are stimulated to proliferate by acetylcholine through an EGFR signalling pathway. Cell Tissue Res. 2013;351:465-75 pubmed publisher