This is a Validated Antibody Database (VAD) review about cow GABRA1, based on 15 published articles (read how Labome selects the articles), using GABRA1 antibody in all methods. It is aimed to help Labome visitors find the most suited GABRA1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
GABRA1 synonym: gamma-aminobutyric acid receptor subunit alpha-1; GABA(A) receptor subunit alpha-1; gamma-aminobutyric acid (GABA) A receptor, alpha 1; gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1

R&D Systems
rabbit polyclonal
  • western blot; human; fig 1
R&D Systems GABRA1 antibody (R&D Systems, PPS022) was used in western blot on human samples (fig 1). J Biol Chem (2016) ncbi
EMD Millipore
rabbit polyclonal
  • immunohistochemistry; mouse; loading ...; fig 4a
EMD Millipore GABRA1 antibody (EMD Millipore, 06-868) was used in immunohistochemistry on mouse samples (fig 4a). elife (2017) ncbi
mouse monoclonal (BD24)
  • western blot; human; loading ...; fig 3a
EMD Millipore GABRA1 antibody (Millipore, BD24) was used in western blot on human samples (fig 3a). Eneuro (2017) ncbi
rabbit polyclonal
  • western blot; mouse; fig 2h
EMD Millipore GABRA1 antibody (Millipore, 06-868) was used in western blot on mouse samples (fig 2h). elife (2017) ncbi
rabbit polyclonal
  • immunocytochemistry; rat; 1:1000; loading ...; fig 1e
  • western blot; rat; 1:1000; loading ...; fig 1d
In order to develop a simple, reversible method for modulating inhibitory synaptic input onto genetically determined cells, EMD Millipore GABRA1 antibody (Millipore, 06-868) was used in immunocytochemistry on rat samples at 1:1000 (fig 1e) and in western blot on rat samples at 1:1000 (fig 1d). Nat Methods (2016) ncbi
mouse monoclonal (BD24)
  • western blot; human; fig 1
EMD Millipore GABRA1 antibody (Millipore, MAB339) was used in western blot on human samples (fig 1). J Biol Chem (2016) ncbi
rabbit polyclonal
  • immunocytochemistry; mouse; 1:250
EMD Millipore GABRA1 antibody (Millipore, 06868) was used in immunocytochemistry on mouse samples at 1:250. Neurobiol Dis (2015) ncbi
rabbit polyclonal
  • immunohistochemistry; mouse; 1:250
EMD Millipore GABRA1 antibody (Millipore, 06868) was used in immunohistochemistry on mouse samples at 1:250. Neurobiol Dis (2015) ncbi
rabbit polyclonal
  • immunohistochemistry - frozen section; mouse; 1:200; loading ...; fig 2a
EMD Millipore GABRA1 antibody (Millipore, 06-868) was used in immunohistochemistry - frozen section on mouse samples at 1:200 (fig 2a). Hippocampus (2015) ncbi
rabbit polyclonal
  • western blot; mouse; fig 6
In order to test if presenilin and nicastrin regulate synaptic function in a gamma-secretase-dependent or -independent manner, EMD Millipore GABRA1 antibody (Upstate, 06-868) was used in western blot on mouse samples (fig 6). Proc Natl Acad Sci U S A (2014) ncbi
mouse monoclonal (BD24)
  • flow cytometry; human
EMD Millipore GABRA1 antibody (Millipore, BD24) was used in flow cytometry on human samples . Neurobiol Dis (2014) ncbi
rabbit polyclonal
  • western blot; human; 1:1000
EMD Millipore GABRA1 antibody (Millipore, 06-868) was used in western blot on human samples at 1:1000. Transl Psychiatry (2013) ncbi
rabbit polyclonal
  • immunohistochemistry - paraffin section; mouse; 1:100
EMD Millipore GABRA1 antibody (Millipore, 06-868) was used in immunohistochemistry - paraffin section on mouse samples at 1:100. Int J Physiol Pathophysiol Pharmacol (2013) ncbi
rabbit polyclonal
  • immunoprecipitation; mouse
  • immunocytochemistry; mouse; 1:250
EMD Millipore GABRA1 antibody (Millipore, 06868) was used in immunoprecipitation on mouse samples and in immunocytochemistry on mouse samples at 1:250. J Biol Chem (2013) ncbi
rabbit polyclonal
  • immunohistochemistry - free floating section; mouse; 1:1000
EMD Millipore GABRA1 antibody (Upstate, 06-868) was used in immunohistochemistry - free floating section on mouse samples at 1:1000. J Comp Neurol (2012) ncbi
mouse monoclonal (BD24)
  • immunocytochemistry; rabbit; 4 ug/ml
EMD Millipore GABRA1 antibody (Chemicon, MAB339) was used in immunocytochemistry on rabbit samples at 4 ug/ml. J Comp Neurol (2008) ncbi
Articles Reviewed
  1. Martenson J, Yamasaki T, Chaudhury N, Albrecht D, Tomita S. Assembly rules for GABAA receptor complexes in the brain. elife. 2017;6: pubmed publisher
  2. Hernandez C, Kong W, Hu N, Zhang Y, Shen W, Jackson L, et al. Altered Channel Conductance States and Gating of GABAA Receptors by a Pore Mutation Linked to Dravet Syndrome. Eneuro. 2017;4: pubmed publisher
  3. Chen M, Wang J, Jiang J, Zheng X, Justice N, Wang K, et al. APP modulates KCC2 expression and function in hippocampal GABAergic inhibition. elife. 2017;6: pubmed publisher
  4. Gross G, Straub C, Perez Sanchez J, Dempsey W, Junge J, Roberts R, et al. An E3-ligase-based method for ablating inhibitory synapses. Nat Methods. 2016;13:673-8 pubmed publisher
  5. Di X, Wang Y, Han D, Fu Y, Duerfeldt A, Blagg B, et al. Grp94 Protein Delivers γ-Aminobutyric Acid Type A (GABAA) Receptors to Hrd1 Protein-mediated Endoplasmic Reticulum-associated Degradation. J Biol Chem. 2016;291:9526-39 pubmed publisher
  6. Arain F, Zhou C, Ding L, Zaidi S, Gallagher M. The developmental evolution of the seizure phenotype and cortical inhibition in mouse models of juvenile myoclonic epilepsy. Neurobiol Dis. 2015;82:164-175 pubmed publisher
  7. Zhou C, Ding L, Deel M, Ferrick E, Emeson R, Gallagher M. Altered intrathalamic GABAA neurotransmission in a mouse model of a human genetic absence epilepsy syndrome. Neurobiol Dis. 2015;73:407-17 pubmed publisher
  8. Calfa G, Li W, Rutherford J, Pozzo Miller L. Excitation/inhibition imbalance and impaired synaptic inhibition in hippocampal area CA3 of Mecp2 knockout mice. Hippocampus. 2015;25:159-68 pubmed publisher
  9. Lee S, Sharma M, S dhof T, Shen J. Synaptic function of nicastrin in hippocampal neurons. Proc Natl Acad Sci U S A. 2014;111:8973-8 pubmed publisher
  10. Todd E, Gurba K, Botzolakis E, Stanic A, Macdonald R. GABAA receptor biogenesis is impaired by the ?2 subunit febrile seizure-associated mutation, GABRG2(R177G). Neurobiol Dis. 2014;69:215-24 pubmed publisher
  11. Fatemi S, Folsom T, Rooney R, Thuras P. Expression of GABAA ?2-, ?1- and ?-receptors are altered significantly in the lateral cerebellum of subjects with schizophrenia, major depression and bipolar disorder. Transl Psychiatry. 2013;3:e303 pubmed publisher
  12. Feng M, Xiang Y, Wang S, Lu W. An autocrine ?-aminobutyric acid signaling system exists in pancreatic ?-cell progenitors of fetal and postnatal mice. Int J Physiol Pathophysiol Pharmacol. 2013;5:91-101 pubmed
  13. Zhou C, Huang Z, Ding L, Deel M, Arain F, Murray C, et al. Altered cortical GABAA receptor composition, physiology, and endocytosis in a mouse model of a human genetic absence epilepsy syndrome. J Biol Chem. 2013;288:21458-72 pubmed publisher
  14. Wang X, Sun Q. Characterization of axo-axonic synapses in the piriform cortex of Mus musculus. J Comp Neurol. 2012;520:832-47 pubmed publisher
  15. Jakobs T, Koizumi A, Masland R. The spatial distribution of glutamatergic inputs to dendrites of retinal ganglion cells. J Comp Neurol. 2008;510:221-36 pubmed publisher