This is a Validated Antibody Database (VAD) review about cow FASN, based on 30 published articles (read how Labome selects the articles), using FASN antibody in all methods. It is aimed to help Labome visitors find the most suited FASN antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
FASN synonym: fatty acid synthase

Cell Signaling Technology
rabbit monoclonal (C20G5)
  • western blot; mouse; loading ...; fig s2g, s4a
Cell Signaling Technology FASN antibody (Cell Signaling, 3180) was used in western blot on mouse samples (fig s2g, s4a). Cell (2018) ncbi
rabbit monoclonal (C20G5)
  • western blot; human; loading ...; fig 6b
Cell Signaling Technology FASN antibody (Cell Signaling, 3180) was used in western blot on human samples (fig 6b). FEBS Lett (2018) ncbi
rabbit monoclonal (C20G5)
  • western blot; mouse; 1:1000; loading ...; fig s2b
Cell Signaling Technology FASN antibody (Cell Signaling, 3180) was used in western blot on mouse samples at 1:1000 (fig s2b). Nat Commun (2018) ncbi
rabbit monoclonal (C20G5)
  • other; human; loading ...; fig 4c
Cell Signaling Technology FASN antibody (Cell Signaling, 3180) was used in other on human samples (fig 4c). Cancer Cell (2018) ncbi
rabbit monoclonal (C20G5)
  • western blot; mouse; loading ...; fig 2b
Cell Signaling Technology FASN antibody (Cell Signaling, 3180S) was used in western blot on mouse samples (fig 2b). Proc Natl Acad Sci U S A (2017) ncbi
rabbit monoclonal (C20G5)
  • immunocytochemistry; human; loading ...; fig 1a
Cell Signaling Technology FASN antibody (Cell Signaling, C20G5) was used in immunocytochemistry on human samples (fig 1a). Mol Cell Biol (2017) ncbi
rabbit monoclonal (C20G5)
  • western blot; human; 1:1000; loading ...; fig 8b
Cell Signaling Technology FASN antibody (Cell Signaling, 3180) was used in western blot on human samples at 1:1000 (fig 8b). Toxicol Appl Pharmacol (2017) ncbi
rabbit monoclonal (C20G5)
  • western blot; mouse; 1:500; loading ...; fig 3c
Cell Signaling Technology FASN antibody (Cell Signaling, 3180) was used in western blot on mouse samples at 1:500 (fig 3c). J Biol Chem (2017) ncbi
rabbit monoclonal (C20G5)
  • reverse phase protein lysate microarray; human; loading ...; fig st6
In order to characterize the molecular identity of uterine carcinosarcomas., Cell Signaling Technology FASN antibody (CST, 3180) was used in reverse phase protein lysate microarray on human samples (fig st6). Cancer Cell (2017) ncbi
rabbit monoclonal (C20G5)
  • immunohistochemistry - paraffin section; mouse; 1:150; loading ...; fig 4
In order to test if de novo lipogenesis is required for liver carcinogenesis, Cell Signaling Technology FASN antibody (Cell Signaling, 3180) was used in immunohistochemistry - paraffin section on mouse samples at 1:150 (fig 4). Cell Cycle (2017) ncbi
rabbit monoclonal (C20G5)
  • reverse phase protein lysate microarray; human; loading ...; fig 3a
In order to describe the features of 228 primary cervical cancers, Cell Signaling Technology FASN antibody (Cell Signaling, 3180) was used in reverse phase protein lysate microarray on human samples (fig 3a). Nature (2017) ncbi
rabbit monoclonal (C20G5)
  • western blot; human; loading ...; fig 4i
Cell Signaling Technology FASN antibody (CST, 3180) was used in western blot on human samples (fig 4i). Nature (2017) ncbi
rabbit monoclonal (C20G5)
  • western blot; mouse; 1:1000; loading ...; fig 7a
In order to analyze the effect of a high-fat diet on liver morphology and physiology, lipid metabolism, immune signaling, energy homeostasis, and stress responses during acute Trypanosoma cruzi infection, Cell Signaling Technology FASN antibody (Cell Signaling, C20G5) was used in western blot on mouse samples at 1:1000 (fig 7a). Parasitol Res (2017) ncbi
rabbit monoclonal (C20G5)
  • western blot; human; 1:1000; loading ...; fig 6a
Cell Signaling Technology FASN antibody (Cell Signaling, 3180) was used in western blot on human samples at 1:1000 (fig 6a). Arch Biochem Biophys (2017) ncbi
rabbit monoclonal (C20G5)
  • western blot; mouse; fig 3
In order to identify and characterize a biliverdin reductase A-glycogen synthase kinase 3beta-peroxisome proliferator-activated receptor alpha axis that regulates hepatic lipid metabolism, Cell Signaling Technology FASN antibody (Cell Signaling, 3180S) was used in western blot on mouse samples (fig 3). J Biol Chem (2016) ncbi
rabbit monoclonal (C20G5)
  • western blot; mouse; 1:1000; loading ...
In order to study the role of endothelial cell exocytosis in cerebral cavernous malformation disease progression, Cell Signaling Technology FASN antibody (Cell Signaling, 3180) was used in western blot on mouse samples at 1:1000. Nat Med (2016) ncbi
rabbit monoclonal (C20G5)
  • proximity ligation assay; mouse; loading ...; fig 1h
  • immunocytochemistry; mouse; loading ...; fig 1f
  • western blot; mouse; 1:1000; loading ...; fig s4c
  • proximity ligation assay; human; loading ...; fig 1b
  • immunoprecipitation; human; loading ...; fig 1a
  • immunocytochemistry; human; loading ...; fig 1d
  • western blot; human; 1:1000; loading ...; fig 1a
Cell Signaling Technology FASN antibody (Cell Signaling, 3180) was used in proximity ligation assay on mouse samples (fig 1h), in immunocytochemistry on mouse samples (fig 1f), in western blot on mouse samples at 1:1000 (fig s4c), in proximity ligation assay on human samples (fig 1b), in immunoprecipitation on human samples (fig 1a), in immunocytochemistry on human samples (fig 1d) and in western blot on human samples at 1:1000 (fig 1a). Nat Immunol (2016) ncbi
rabbit monoclonal (C20G5)
  • western blot; human; loading ...; fig 3e
In order to find strategies to suppress glioblastoma growth via sterol regulatory element-binding protein-1 inhibition, Cell Signaling Technology FASN antibody (Cell signaling, 3180) was used in western blot on human samples (fig 3e). Clin Cancer Res (2016) ncbi
rabbit monoclonal (C20G5)
  • western blot; mouse; 1:1000; fig 4
Cell Signaling Technology FASN antibody (Cell Signaling, 3180) was used in western blot on mouse samples at 1:1000 (fig 4). Sci Rep (2016) ncbi
rabbit monoclonal (C20G5)
  • immunohistochemistry; mouse; 1:100; fig 3d
Cell Signaling Technology FASN antibody (Cell Signaling, 3180) was used in immunohistochemistry on mouse samples at 1:100 (fig 3d). Sci Rep (2016) ncbi
rabbit monoclonal (C20G5)
  • western blot; mouse; 1:1000; fig s8
Cell Signaling Technology FASN antibody (Cell Signaling, 3180) was used in western blot on mouse samples at 1:1000 (fig s8). Nat Commun (2015) ncbi
rabbit monoclonal (C20G5)
  • western blot; mouse; 1:1000; fig 4
Cell Signaling Technology FASN antibody (Cell Signaling, 3180) was used in western blot on mouse samples at 1:1000 (fig 4). Nat Commun (2015) ncbi
rabbit monoclonal (C20G5)
  • immunohistochemistry; human; loading ...; fig 2c
  • western blot; mouse; fig 8a
Cell Signaling Technology FASN antibody (Cell Signaling, 3180) was used in immunohistochemistry on human samples (fig 2c) and in western blot on mouse samples (fig 8a). EMBO Rep (2015) ncbi
rabbit monoclonal (C20G5)
  • western blot; mouse; 1:1000; fig 2
Cell Signaling Technology FASN antibody (Cell Signaling, 3180) was used in western blot on mouse samples at 1:1000 (fig 2). Br J Pharmacol (2015) ncbi
rabbit monoclonal (C20G5)
  • western blot; mouse
In order to examine the role of coregulators of nuclear receptor action in thyroid hormone action, Cell Signaling Technology FASN antibody (Cell Signaling, C20G5) was used in western blot on mouse samples . Mol Cell Biol (2015) ncbi
rabbit monoclonal (C20G5)
  • western blot; human
Cell Signaling Technology FASN antibody (Cell Signaling, 3180) was used in western blot on human samples . PLoS ONE (2014) ncbi
rabbit monoclonal (C20G5)
  • western blot; mouse
In order to investigate the effect of chronic beta3-adrenergic receptor activation on lipolysis and de novo lipogenesis in brown, beige, and white adipose tissues, Cell Signaling Technology FASN antibody (Cell Signal, 3180) was used in western blot on mouse samples . J Lipid Res (2014) ncbi
rabbit monoclonal (C20G5)
  • western blot; human; 1:1000
Cell Signaling Technology FASN antibody (CST, 3180) was used in western blot on human samples at 1:1000. J Agric Food Chem (2014) ncbi
rabbit monoclonal (C20G5)
  • western blot; mouse; 1:1000; fig s10e
Cell Signaling Technology FASN antibody (Cell Signaling, 3180S) was used in western blot on mouse samples at 1:1000 (fig s10e). Nat Commun (2013) ncbi
rabbit monoclonal (C20G5)
  • immunohistochemistry - paraffin section; mouse
  • western blot; mouse
Cell Signaling Technology FASN antibody (Cell Signalling, 3180) was used in immunohistochemistry - paraffin section on mouse samples and in western blot on mouse samples . PLoS ONE (2013) ncbi
Articles Reviewed
  1. Grohmann M, Wiede F, Dodd G, Gurzov E, Ooi G, Butt T, et al. Obesity Drives STAT-1-Dependent NASH and STAT-3-Dependent HCC. Cell. 2018;175:1289-1306.e20 pubmed publisher
  2. Guo J, Fang W, Chen X, Lin Y, Hu G, Wei J, et al. Upstream stimulating factor 1 suppresses autophagy and hepatic lipid droplet catabolism by activating mTOR. FEBS Lett. 2018;592:2725-2738 pubmed publisher
  3. Li T, Song L, Sun Y, Li J, Yi C, Lam S, et al. Tip60-mediated lipin 1 acetylation and ER translocation determine triacylglycerol synthesis rate. Nat Commun. 2018;9:1916 pubmed publisher
  4. Ng P, Li J, Jeong K, Shao S, Chen H, Tsang Y, et al. Systematic Functional Annotation of Somatic Mutations in Cancer. Cancer Cell. 2018;33:450-462.e10 pubmed publisher
  5. Li S, Mi L, Yu L, Yu Q, Liu T, Wang G, et al. Zbtb7b engages the long noncoding RNA Blnc1 to drive brown and beige fat development and thermogenesis. Proc Natl Acad Sci U S A. 2017;114:E7111-E7120 pubmed publisher
  6. Al Khalaf H, Amir M, Al Mohanna F, Tulbah A, Al Sayed A, Aboussekhra A. Obesity and p16INK4A Downregulation Activate Breast Adipocytes and Promote Their Protumorigenicity. Mol Cell Biol. 2017;37: pubmed publisher
  7. Bai X, Hong W, Cai P, Chen Y, Xu C, Cao D, et al. Valproate induced hepatic steatosis by enhanced fatty acid uptake and triglyceride synthesis. Toxicol Appl Pharmacol. 2017;324:12-25 pubmed publisher
  8. Song Z, Xiaoli A, Zhang Q, Zhang Y, Yang E, Wang S, et al. Cyclin C regulates adipogenesis by stimulating transcriptional activity of CCAAT/enhancer-binding protein ?. J Biol Chem. 2017;292:8918-8932 pubmed publisher
  9. Cherniack A, Shen H, Walter V, Stewart C, Murray B, Bowlby R, et al. Integrated Molecular Characterization of Uterine Carcinosarcoma. Cancer Cell. 2017;31:411-423 pubmed publisher
  10. Che L, Pilo M, Cigliano A, Latte G, Simile M, Ribback S, et al. Oncogene dependent requirement of fatty acid synthase in hepatocellular carcinoma. Cell Cycle. 2017;16:499-507 pubmed publisher
  11. . Integrated genomic and molecular characterization of cervical cancer. Nature. 2017;543:378-384 pubmed publisher
  12. Dey P, Baddour J, Muller F, Wu C, Wang H, Liao W, et al. Genomic deletion of malic enzyme 2 confers collateral lethality in pancreatic cancer. Nature. 2017;542:119-123 pubmed publisher
  13. Lizardo K, Almonte V, Law C, Aiyyappan J, Cui M, Nagajyothi J. Diet regulates liver autophagy differentially in murine acute Trypanosoma cruzi infection. Parasitol Res. 2017;116:711-723 pubmed publisher
  14. Marmisolle I, Martínez J, Liu J, Mastrogiovanni M, Fergusson M, Rovira I, et al. Reciprocal regulation of acetyl-CoA carboxylase 1 and senescence in human fibroblasts involves oxidant mediated p38 MAPK activation. Arch Biochem Biophys. 2017;613:12-22 pubmed publisher
  15. Hinds T, Burns K, Hosick P, McBeth L, Nestor Kalinoski A, Drummond H, et al. Biliverdin Reductase A Attenuates Hepatic Steatosis by Inhibition of Glycogen Synthase Kinase (GSK) 3? Phosphorylation of Serine 73 of Peroxisome Proliferator-activated Receptor (PPAR) ?. J Biol Chem. 2016;291:25179-25191 pubmed
  16. Jenny Zhou H, Qin L, Zhang H, Tang W, Ji W, He Y, et al. Endothelial exocytosis of angiopoietin-2 resulting from CCM3 deficiency contributes to cerebral cavernous malformation. Nat Med. 2016;22:1033-1042 pubmed publisher
  17. Cader M, Boroviak K, Zhang Q, Assadi G, Kempster S, Sewell G, et al. C13orf31 (FAMIN) is a central regulator of immunometabolic function. Nat Immunol. 2016;17:1046-56 pubmed publisher
  18. Geng F, Cheng X, Wu X, Yoo J, Cheng C, Guo J, et al. Inhibition of SOAT1 Suppresses Glioblastoma Growth via Blocking SREBP-1-Mediated Lipogenesis. Clin Cancer Res. 2016;22:5337-5348 pubmed
  19. Thomas A, Belaidi E, Aron Wisnewsky J, van der Zon G, Levy P, Clement K, et al. Hypoxia-inducible factor prolyl hydroxylase 1 (PHD1) deficiency promotes hepatic steatosis and liver-specific insulin resistance in mice. Sci Rep. 2016;6:24618 pubmed publisher
  20. Lee K, Hsieh Y, Yang Y, Chan C, Huang Y, Lin H. Aliskiren Reduces Hepatic steatosis and Epididymal Fat Mass and Increases Skeletal Muscle Insulin Sensitivity in High-Fat Diet-Fed Mice. Sci Rep. 2016;6:18899 pubmed publisher
  21. Nemazanyy I, Montagnac G, Russell R, Morzyglod L, Burnol A, Guan K, et al. Class III PI3K regulates organismal glucose homeostasis by providing negative feedback on hepatic insulin signalling. Nat Commun. 2015;6:8283 pubmed publisher
  22. Brina D, Miluzio A, Ricciardi S, Clarke K, Davidsen P, Viero G, et al. eIF6 coordinates insulin sensitivity and lipid metabolism by coupling translation to transcription. Nat Commun. 2015;6:8261 pubmed publisher
  23. Zidek L, Ackermann T, Hartleben G, Eichwald S, Kortman G, Kiehntopf M, et al. Deficiency in mTORC1-controlled C/EBPβ-mRNA translation improves metabolic health in mice. EMBO Rep. 2015;16:1022-36 pubmed publisher
  24. Zeng X, Wang H, Bai F, Zhou X, Li S, Ren L, et al. Identification of matrine as a promising novel drug for hepatic steatosis and glucose intolerance with HSP72 as an upstream target. Br J Pharmacol. 2015;172:4303-18 pubmed publisher
  25. Shimizu H, Astapova I, Ye F, Bilban M, Cohen R, Hollenberg A. NCoR1 and SMRT play unique roles in thyroid hormone action in vivo. Mol Cell Biol. 2015;35:555-65 pubmed publisher
  26. Daniëls V, Smans K, Royaux I, Chypre M, Swinnen J, Zaidi N. Cancer cells differentially activate and thrive on de novo lipid synthesis pathways in a low-lipid environment. PLoS ONE. 2014;9:e106913 pubmed publisher
  27. Mottillo E, Balasubramanian P, Lee Y, Weng C, Kershaw E, Granneman J. Coupling of lipolysis and de novo lipogenesis in brown, beige, and white adipose tissues during chronic β3-adrenergic receptor activation. J Lipid Res. 2014;55:2276-86 pubmed publisher
  28. Liu J, Zheng L, Wu N, Ma L, Zhong J, Liu G, et al. Oleanolic acid induces metabolic adaptation in cancer cells by activating the AMP-activated protein kinase pathway. J Agric Food Chem. 2014;62:5528-37 pubmed publisher
  29. Lanaspa M, Ishimoto T, Li N, Cicerchi C, Orlicky D, Ruzycki P, et al. Endogenous fructose production and metabolism in the liver contributes to the development of metabolic syndrome. Nat Commun. 2013;4:2434 pubmed publisher
  30. Antony N, Weir J, McDougall A, Mantamadiotis T, Meikle P, Cole T, et al. cAMP response element binding protein1 is essential for activation of steroyl co-enzyme a desaturase 1 (Scd1) in mouse lung type II epithelial cells. PLoS ONE. 2013;8:e59763 pubmed publisher