This is a Validated Antibody Database (VAD) review about cow ERBB3, based on 13 published articles (read how Labome selects the articles), using ERBB3 antibody in all methods. It is aimed to help Labome visitors find the most suited ERBB3 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
ERBB3 synonym: receptor tyrosine-protein kinase erbB-3; v-erb-b2 erythroblastic leukemia viral oncogene homolog 3

Invitrogen
mouse monoclonal (2F12)
  • western blot; rat; 1:1000; loading ...; fig 5c
In order to explore the role of Necl4 in peripheral myelination, Invitrogen ERBB3 antibody (NeoMarkers, MS-201-P1) was used in western blot on rat samples at 1:1000 (fig 5c). J Biol Chem (2017) ncbi
mouse monoclonal (2F12)
  • reverse phase protein lysate microarray; human; loading ...; fig 3a
In order to describe the features of 228 primary cervical cancers, Invitrogen ERBB3 antibody (Lab Vision, MS-201-P1ABX) was used in reverse phase protein lysate microarray on human samples (fig 3a). Nature (2017) ncbi
mouse monoclonal (2F12)
In order to identify the effects of the epidermal growth factor receptor 2 and the protein tyrosine kinase 6 in relation to breast cancer treatment, Invitrogen ERBB3 antibody (Thermo Fisher Scientific, MS-201-P1) was used . Mol Oncol (2015) ncbi
mouse monoclonal (2F12)
  • immunoprecipitation; human
  • western blot; human
In order to study mechanism of resistance to the FGFR inhibitor BGJ398 and the FGFR inhibitor ponatinib, Invitrogen ERBB3 antibody (Thermo Scientific, MA5-12675) was used in immunoprecipitation on human samples and in western blot on human samples . Oncogene (2015) ncbi
mouse monoclonal (2F12)
  • proximity ligation assay; human; 1:40
In order to research p21 expression and HER2/HER3 heterodimers and prediction of adjuvant trastuzumab response in HER2+ breast cancer, Invitrogen ERBB3 antibody (Neomarkers, 2F12) was used in proximity ligation assay on human samples at 1:40. Breast Cancer Res Treat (2014) ncbi
mouse monoclonal (2F12)
  • western blot; human; fig 1c
In order to suggest that Akt activation by ERBB3/HER2 limits the effectiveness of EGFR inhibition, Invitrogen ERBB3 antibody (Thermo Scientific, 2F12) was used in western blot on human samples (fig 1c). Mol Cancer Ther (2014) ncbi
mouse monoclonal (2F12)
  • western blot; human; fig 5
In order to discuss targeting MiR-221/-222 to treat breast cancer, Invitrogen ERBB3 antibody (Thermo Scientific, MS-201-P1) was used in western blot on human samples (fig 5). Br J Cancer (2013) ncbi
EMD Millipore
mouse monoclonal (2F12)
  • western blot; human; loading ...; fig S1
In order to study the contribution of the heregulin-1/HER3-driven pathway to hepatocellular carcinoma, EMD Millipore ERBB3 antibody (Merck Millipore, 05-390) was used in western blot on human samples (fig S1). J Exp Clin Cancer Res (2016) ncbi
mouse monoclonal (2F12)
  • western blot; human; fig 1
EMD Millipore ERBB3 antibody (Millipore, 05-390) was used in western blot on human samples (fig 1). Tumour Biol (2016) ncbi
mouse monoclonal (2F12)
  • immunoprecipitation; human; fig 3
  • western blot; human; fig 3
EMD Millipore ERBB3 antibody (Millipore, 05-390) was used in immunoprecipitation on human samples (fig 3) and in western blot on human samples (fig 3). J Cell Mol Med (2016) ncbi
mouse monoclonal (2F12)
  • western blot; human; fig 2
In order to study human breast cancer cell lines and how Heregulin-HER3-HER2 signaling promotes matrix metalloproteinase-dependent blood-brain-barrier transendothelial migration, EMD Millipore ERBB3 antibody (Millipore, 2F12) was used in western blot on human samples (fig 2). Oncotarget (2015) ncbi
mouse monoclonal (2F12)
  • immunocytochemistry; human
In order to study the role of flotillin in the oncogenic effect of ErbB, EMD Millipore ERBB3 antibody (Millipore, 2F12) was used in immunocytochemistry on human samples . Biochim Biophys Acta (2014) ncbi
mouse monoclonal (2F12)
  • immunohistochemistry - frozen section; human
In order to characterize nerve hyperexcitability and neuromuscular junction remodeling in Schwartz-Jampel syndrome, EMD Millipore ERBB3 antibody (Life Millipore, 2F12) was used in immunohistochemistry - frozen section on human samples . Neuromuscul Disord (2013) ncbi
Articles Reviewed
  1. Heffernan C, Jain M, Liu T, Kim H, Barretto K, Li H, et al. Nectin-like 4 Complexes with Choline Transporter-like Protein-1 and Regulates Schwann Cell Choline Homeostasis and Lipid Biogenesis in Vitro. J Biol Chem. 2017;292:4484-4498 pubmed publisher
  2. . Integrated genomic and molecular characterization of cervical cancer. Nature. 2017;543:378-384 pubmed publisher
  3. Buta C, Benabou E, Lequoy M, Régnault H, Wendum D, Meratbene F, et al. Heregulin-1ß and HER3 in hepatocellular carcinoma: status and regulation by insulin. J Exp Clin Cancer Res. 2016;35:126 pubmed publisher
  4. Cao K, Gong H, Qiu Z, Wen Q, Zhang B, Tang T, et al. Hepatitis B virus X protein reduces the stability of Nrdp1 to up-regulate ErbB3 in hepatocellular carcinoma cells. Tumour Biol. 2016;37:10375-82 pubmed publisher
  5. Wu Y, Wang L, Bao H, Zou S, Fu C, Gong H, et al. Nrdp1S, short variant of Nrdp1, inhibits human glioma progression by increasing Nrdp1-mediated ErbB3 ubiquitination and degradation. J Cell Mol Med. 2016;20:422-9 pubmed publisher
  6. Momeny M, Saunus J, Marturana F, McCart Reed A, Black D, Sala G, et al. Heregulin-HER3-HER2 signaling promotes matrix metalloproteinase-dependent blood-brain-barrier transendothelial migration of human breast cancer cell lines. Oncotarget. 2015;6:3932-46 pubmed
  7. Falkenberg N, Anastasov N, Höfig I, Bashkueva K, Lindner K, Höfler H, et al. Additive impact of HER2-/PTK6-RNAi on interactions with HER3 or IGF-1R leads to reduced breast cancer progression in vivo. Mol Oncol. 2015;9:282-94 pubmed publisher
  8. Wang J, Mikse O, Liao R, Li Y, Tan L, Jänne P, et al. Ligand-associated ERBB2/3 activation confers acquired resistance to FGFR inhibition in FGFR3-dependent cancer cells. Oncogene. 2015;34:2167-77 pubmed publisher
  9. Asp N, Pust S, Sandvig K. Flotillin depletion affects ErbB protein levels in different human breast cancer cells. Biochim Biophys Acta. 2014;1843:1987-96 pubmed publisher
  10. Green A, Barros F, Abdel Fatah T, Moseley P, Nolan C, Durham A, et al. HER2/HER3 heterodimers and p21 expression are capable of predicting adjuvant trastuzumab response in HER2+ breast cancer. Breast Cancer Res Treat. 2014;145:33-44 pubmed publisher
  11. Zhang L, Castanaro C, Luan B, Yang K, Fan L, Fairhurst J, et al. ERBB3/HER2 signaling promotes resistance to EGFR blockade in head and neck and colorectal cancer models. Mol Cancer Ther. 2014;13:1345-55 pubmed publisher
  12. Falkenberg N, Anastasov N, Rappl K, Braselmann H, Auer G, Walch A, et al. MiR-221/-222 differentiate prognostic groups in advanced breast cancers and influence cell invasion. Br J Cancer. 2013;109:2714-23 pubmed publisher
  13. Bauché S, Boerio D, Davoine C, Bernard V, Stum M, Bureau C, et al. Peripheral nerve hyperexcitability with preterminal nerve and neuromuscular junction remodeling is a hallmark of Schwartz-Jampel syndrome. Neuromuscul Disord. 2013;23:998-1009 pubmed publisher