This is a Validated Antibody Database (VAD) review about cow CRYAA, based on 10 published articles (read how Labome selects the articles), using CRYAA antibody in all methods. It is aimed to help Labome visitors find the most suited CRYAA antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
CRYAA synonym: alpha-crystallin A chain

Knockout validation
Enzo Life Sciences
mouse monoclonal (1B6.1-3G4)
  • western blot knockout validation; mouse; 1:1000; fig 1
Enzo Life Sciences CRYAA antibody (Enzo Life Sciences, ADI-SPA-222-D) was used in western blot knockout validation on mouse samples at 1:1000 (fig 1). Genom Data (2016) ncbi
Enzo Life Sciences
mouse monoclonal (1B6.1-3G4)
  • western blot knockout validation; mouse; 1:1000; fig 1
Enzo Life Sciences CRYAA antibody (Enzo Life Sciences, ADI-SPA-222-D) was used in western blot knockout validation on mouse samples at 1:1000 (fig 1). Genom Data (2016) ncbi
mouse monoclonal (1B6.1-3G4)
  • immunocytochemistry; human; fig 1
Enzo Life Sciences CRYAA antibody (Enzo, 1B6.1-3G4) was used in immunocytochemistry on human samples (fig 1). Mol Biol Cell (2016) ncbi
mouse monoclonal (1B6.1-3G4)
  • western blot; human; fig 1
In order to characterize the role of BAG3-HSPB8 in mitosis, Enzo Life Sciences CRYAA antibody (StressGene, SPA222) was used in western blot on human samples (fig 1). PLoS Genet (2015) ncbi
mouse monoclonal (1B6.1-3G4)
  • immunohistochemistry - frozen section; mouse; 1:100; fig 5
Enzo Life Sciences CRYAA antibody (Stressgen, 1B6.1-3G4) was used in immunohistochemistry - frozen section on mouse samples at 1:100 (fig 5). Mol Ther Nucleic Acids (2015) ncbi
mouse monoclonal (1B6.1-3G4)
  • immunohistochemistry; mouse; loading ...; fig 4b
Enzo Life Sciences CRYAA antibody (Enzo Life Sciences, 1B6.1-3G4) was used in immunohistochemistry on mouse samples (fig 4b). Oncogene (2015) ncbi
mouse monoclonal (1B6.1-3G4)
  • immunohistochemistry - paraffin section; human; fig 1
Enzo Life Sciences CRYAA antibody (Enzo, 1B6.1 ?C 3G4) was used in immunohistochemistry - paraffin section on human samples (fig 1). Am J Respir Cell Mol Biol (2015) ncbi
mouse monoclonal (1B6.1-3G4)
  • western blot; human; 1:1000
In order to determine if the type of contraction affects the localization or phosphorylation of sHSPs, HSP27, and alphaB-crystallin in human muscle, Enzo Life Sciences CRYAA antibody (Stressgen, SPA222) was used in western blot on human samples at 1:1000. J Appl Physiol (1985) (2014) ncbi
mouse monoclonal (1B6.1-3G4)
  • immunohistochemistry - paraffin section; rat; 1:100
  • immunocytochemistry; rat; 1:200
  • western blot; rat
Enzo Life Sciences CRYAA antibody (Enzo Life Science, ADI-SPA-222-F) was used in immunohistochemistry - paraffin section on rat samples at 1:100, in immunocytochemistry on rat samples at 1:200 and in western blot on rat samples . PLoS ONE (2014) ncbi
mouse monoclonal (1B6.1-3G4)
  • immunohistochemistry - paraffin section; human; 1:200
  • western blot; human
In order to study the role of alphaB-crystallin in modulating triple-negative breast cancer brain metastasis, Enzo Life Sciences CRYAA antibody (Enzo Life Sciences / Stressgen, 1B6.1-3G4) was used in immunohistochemistry - paraffin section on human samples at 1:200 and in western blot on human samples . Clin Cancer Res (2014) ncbi
Invitrogen
rabbit polyclonal
In order to study lentoid bodies in adult avian retinas, Invitrogen CRYAA antibody (BioReagents, PA1-009) was used . J Comp Pathol (2006) ncbi
Articles Reviewed
  1. Toft D, Fuller M, Schipma M, Chen F, Cryns V, Layden B. ?B-crystallin and HspB2 deficiency is protective from diet-induced glucose intolerance. Genom Data. 2016;9:10-7 pubmed publisher
  2. Nivon M, Fort L, Muller P, Richet E, Simon S, Guey B, et al. NF?B is a central regulator of protein quality control in response to protein aggregation stresses via autophagy modulation. Mol Biol Cell. 2016;27:1712-27 pubmed publisher
  3. Fuchs M, Luthold C, Guilbert S, Varlet A, Lambert H, Jetté A, et al. A Role for the Chaperone Complex BAG3-HSPB8 in Actin Dynamics, Spindle Orientation and Proper Chromosome Segregation during Mitosis. PLoS Genet. 2015;11:e1005582 pubmed publisher
  4. Watanabe Y, Kazuki Y, Kazuki K, Ebiki M, Nakanishi M, Nakamura K, et al. Use of a Human Artificial Chromosome for Delivering Trophic Factors in a Rodent Model of Amyotrophic Lateral Sclerosis. Mol Ther Nucleic Acids. 2015;4:e253 pubmed publisher
  5. Malin D, Strekalova E, Petrovic V, Rajanala H, Sharma B, Ugolkov A, et al. ERK-regulated αB-crystallin induction by matrix detachment inhibits anoikis and promotes lung metastasis in vivo. Oncogene. 2015;34:5626-34 pubmed publisher
  6. Bellaye P, Burgy O, Colas J, Fabre A, Marchal Sommé J, Crestani B, et al. Antifibrotic role of ?B-crystallin inhibition in pleural and subpleural fibrosis. Am J Respir Cell Mol Biol. 2015;52:244-52 pubmed publisher
  7. Frankenberg N, Lamb G, Overgaard K, Murphy R, Vissing K. Small heat shock proteins translocate to the cytoskeleton in human skeletal muscle following eccentric exercise independently of phosphorylation. J Appl Physiol (1985). 2014;116:1463-72 pubmed publisher
  8. Tang S, Lv Y, Chen H, Adam A, Cheng Y, Hartung J, et al. Comparative analysis of ?B-crystallin expression in heat-stressed myocardial cells in vivo and in vitro. PLoS ONE. 2014;9:e86937 pubmed publisher
  9. Malin D, Strekalova E, Petrovic V, Deal A, Al Ahmad A, Adamo B, et al. ?B-crystallin: a novel regulator of breast cancer metastasis to the brain. Clin Cancer Res. 2014;20:56-67 pubmed publisher
  10. Zeiss C, Dubielzig R. Lentoid bodies in the avian retina. J Comp Pathol. 2006;135:243-8 pubmed