This is a Validated Antibody Database (VAD) review about cow CBLB, based on 4 published articles (read how Labome selects the articles), using CBLB antibody in all methods. It is aimed to help Labome visitors find the most suited CBLB antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
CBLB synonym: E3 ubiquitin-protein ligase CBL-B; Cas-Br-M ecotropic retroviral transforming sequence b

Knockout validation
Cell Signaling Technology
rabbit monoclonal (D3C12)
  • western blot knockout validation; mouse; fig 1
Cell Signaling Technology CBLB antibody (Cell Signaling, D3C12) was used in western blot knockout validation on mouse samples (fig 1). Oncotarget (2016) ncbi
Cell Signaling Technology
rabbit monoclonal (D3C12)
  • western blot; human; fig 8c
Cell Signaling Technology CBLB antibody (Cell Signaling, 9498S) was used in western blot on human samples (fig 8c). Cancer Cell (2017) ncbi
rabbit monoclonal (D3C12)
  • western blot knockout validation; mouse; fig 1
Cell Signaling Technology CBLB antibody (Cell Signaling, D3C12) was used in western blot knockout validation on mouse samples (fig 1). Oncotarget (2016) ncbi
rabbit monoclonal (D3C12)
  • western blot; human; loading ...; fig 7
Cell Signaling Technology CBLB antibody (Cell Signaling, 9498) was used in western blot on human samples (fig 7). J Biol Chem (2016) ncbi
rabbit monoclonal (D3C12)
  • western blot; human
In order to study the molecular signaling responsible for retinoic acid-induced differentiation, Cell Signaling Technology CBLB antibody (Cell Signaling, 9498) was used in western blot on human samples . PLoS ONE (2015) ncbi
Articles Reviewed
  1. Robles Valero J, Lorenzo Martín L, Menacho Márquez M, Fernández Pisonero I, Abad A, Camos M, et al. A Paradoxical Tumor-Suppressor Role for the Rac1 Exchange Factor Vav1 in T Cell Acute Lymphoblastic Leukemia. Cancer Cell. 2017;32:608-623.e9 pubmed publisher
  2. Goetz B, An W, Mohapatra B, Zutshi N, Iseka F, Storck M, et al. A novel CBL-Bflox/flox mouse model allows tissue-selective fully conditional CBL/CBL-B double-knockout: CD4-Cre mediated CBL/CBL-B deletion occurs in both T-cells and hematopoietic stem cells. Oncotarget. 2016;7:51107-51123 pubmed publisher
  3. Rorsman C, Tsioumpekou M, Heldin C, Lennartsson J. The Ubiquitin Ligases c-Cbl and Cbl-b Negatively Regulate Platelet-derived Growth Factor (PDGF) BB-induced Chemotaxis by Affecting PDGF Receptor ? (PDGFR?) Internalization and Signaling. J Biol Chem. 2016;291:11608-18 pubmed publisher
  4. Bunaciu R, Jensen H, Macdonald R, Latocha D, Varner J, Yen A. 6-Formylindolo(3,2-b)Carbazole (FICZ) Modulates the Signalsome Responsible for RA-Induced Differentiation of HL-60 Myeloblastic Leukemia Cells. PLoS ONE. 2015;10:e0135668 pubmed publisher