This is a Validated Antibody Database (VAD) review about cow ATG7, based on 33 published articles (read how Labome selects the articles), using ATG7 antibody in all methods. It is aimed to help Labome visitors find the most suited ATG7 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
ATG7 synonym: ubiquitin-like modifier-activating enzyme ATG7; ATG7 autophagy related 7 homolog

Knockout validation
Cell Signaling Technology
rabbit monoclonal (D12B11)
  • western blot knockout validation; mouse; loading ...; fig 1h
Cell Signaling Technology ATG7 antibody (Cell Signaling, 8558) was used in western blot knockout validation on mouse samples (fig 1h). Dev Cell (2017) ncbi
Cell Signaling Technology
rabbit monoclonal (D12B11)
  • western blot knockout validation; human; 1:1000; loading ...; fig 1e
Cell Signaling Technology ATG7 antibody (Cell Signaling, 8558) was used in western blot knockout validation on human samples at 1:1000 (fig 1e). Cell Rep (2017) ncbi
Cell Signaling Technology
rabbit monoclonal (D12B11)
  • western blot knockout validation; mouse; loading ...; fig s1b
Cell Signaling Technology ATG7 antibody (Cell Signaling Technology, 8558) was used in western blot knockout validation on mouse samples (fig s1b). Cell Death Dis (2016) ncbi
Cell Signaling Technology
rabbit monoclonal (D12B11)
  • western blot; mouse; 1:1000; loading ...; fig 6d
Cell Signaling Technology ATG7 antibody (Cell Signaling, 8558) was used in western blot on mouse samples at 1:1000 (fig 6d). Nat Commun (2018) ncbi
rabbit monoclonal (D12B11)
  • western blot; mouse; 1:1000; loading ...; fig 2b
Cell Signaling Technology ATG7 antibody (Cell Signaling, 8558) was used in western blot on mouse samples at 1:1000 (fig 2b). Cancer Res (2018) ncbi
rabbit monoclonal (D12B11)
  • other; human; loading ...; fig 4c
Cell Signaling Technology ATG7 antibody (Cell Signaling, 8558) was used in other on human samples (fig 4c). Cancer Cell (2018) ncbi
rabbit monoclonal (D12B11)
  • western blot; human; fig 5b
Cell Signaling Technology ATG7 antibody (Cell Signaling, 8558) was used in western blot on human samples (fig 5b). Cancer Res (2018) ncbi
rabbit monoclonal (D12B11)
  • western blot knockout validation; mouse; loading ...; fig 1h
Cell Signaling Technology ATG7 antibody (Cell Signaling, 8558) was used in western blot knockout validation on mouse samples (fig 1h). Dev Cell (2017) ncbi
rabbit monoclonal (D12B11)
  • western blot; human; loading ...; fig s7
Cell Signaling Technology ATG7 antibody (Cell Signaling, 8558S) was used in western blot on human samples (fig s7). PLoS ONE (2017) ncbi
rabbit monoclonal (D12B11)
  • western blot knockout validation; human; 1:1000; loading ...; fig 1e
Cell Signaling Technology ATG7 antibody (Cell Signaling, 8558) was used in western blot knockout validation on human samples at 1:1000 (fig 1e). Cell Rep (2017) ncbi
rabbit monoclonal (D12B11)
  • western blot; human; loading ...; fig 10c
Cell Signaling Technology ATG7 antibody (CST, 8558) was used in western blot on human samples (fig 10c). elife (2017) ncbi
rabbit monoclonal (D12B11)
  • western blot; human; loading ...; fig 7a
Cell Signaling Technology ATG7 antibody (Cell Signaling, 8558) was used in western blot on human samples (fig 7a). Autophagy (2017) ncbi
rabbit monoclonal (D12B11)
  • western blot; rat; 1:1000; loading ...; fig 4a
In order to test if autophagy contributes to aldosterone-induced mesangial cell proliferation, Cell Signaling Technology ATG7 antibody (Cell Signaling, 8558) was used in western blot on rat samples at 1:1000 (fig 4a). Mol Med Rep (2016) ncbi
rabbit monoclonal (D12B11)
  • western blot; human; loading ...; fig 3c
Cell Signaling Technology ATG7 antibody (Cell Signaling, 8558) was used in western blot on human samples (fig 3c). Autophagy (2016) ncbi
rabbit monoclonal (D12B11)
  • western blot knockout validation; mouse; loading ...; fig s1b
Cell Signaling Technology ATG7 antibody (Cell Signaling Technology, 8558) was used in western blot knockout validation on mouse samples (fig s1b). Cell Death Dis (2016) ncbi
rabbit monoclonal (D12B11)
  • western blot; mouse; loading ...; fig 6a
In order to characterize cardiac defects in interleukin-18 knock out mice, Cell Signaling Technology ATG7 antibody (Cell Signaling Technology, 8558) was used in western blot on mouse samples (fig 6a). Am J Physiol Heart Circ Physiol (2016) ncbi
rabbit monoclonal (D12B11)
  • western blot; cow; 1:1000; fig 1
In order to study the mammary gland during the dry period and the effect of heat stress on markers of autophagy, Cell Signaling Technology ATG7 antibody (Cell Signaling, 8558) was used in western blot on cow samples at 1:1000 (fig 1). J Dairy Sci (2016) ncbi
rabbit monoclonal (D12B11)
  • immunohistochemistry - frozen section; mouse; 1:500; fig 6
Cell Signaling Technology ATG7 antibody (Cell Signaling Technology, D12B11) was used in immunohistochemistry - frozen section on mouse samples at 1:500 (fig 6). J Transl Med (2016) ncbi
rabbit monoclonal (D12B11)
  • western blot; mouse; 1:1000; loading ...; fig 6b
Cell Signaling Technology ATG7 antibody (Cell Signaling Technology, 8558) was used in western blot on mouse samples at 1:1000 (fig 6b). Autophagy (2016) ncbi
rabbit monoclonal (D12B11)
  • western blot; mouse; 1:1000; loading ...; fig 6b
Cell Signaling Technology ATG7 antibody (Cell Signaling, 8558) was used in western blot on mouse samples at 1:1000 (fig 6b). Oncotarget (2016) ncbi
rabbit monoclonal (D12B11)
  • western blot; mouse; 1:1000; fig 2
In order to investigate the impact of neuronal Atg7 depletion using a mouse model of severe neonatal hypoxia-ischemia, Cell Signaling Technology ATG7 antibody (Cell Signaling Technology, 8558) was used in western blot on mouse samples at 1:1000 (fig 2). Autophagy (2016) ncbi
rabbit monoclonal (D12B11)
  • western blot; human; fig 1
Cell Signaling Technology ATG7 antibody (Cell Signaling Technology, 8558) was used in western blot on human samples (fig 1). Nature (2015) ncbi
rabbit monoclonal (D12B11)
  • western blot; human; fig 4f
Cell Signaling Technology ATG7 antibody (Cell Signaling Technology, 8558) was used in western blot on human samples (fig 4f). Oncotarget (2015) ncbi
rabbit monoclonal (D12B11)
  • western blot; human; fig 7
In order to assess the activity of a novel dual PI3K/mTOR inhibitor on mesothelioma, Cell Signaling Technology ATG7 antibody (Cell Signaling, 8558) was used in western blot on human samples (fig 7). PLoS ONE (2015) ncbi
rabbit monoclonal (D12B11)
  • western blot; human; loading ...; fig 4e
Cell Signaling Technology ATG7 antibody (Cell Signaling, 8558) was used in western blot on human samples (fig 4e). Oncotarget (2015) ncbi
rabbit monoclonal (D12B11)
  • western blot; human; fig 2
In order to determine stress resistance to breast cancer cells and neuroblastoma by BAG3 function and estrogen receptor alpha that regulates non-canonical autophagy, Cell Signaling Technology ATG7 antibody (Cell signaling, 8558) was used in western blot on human samples (fig 2). Cell Death Dis (2015) ncbi
rabbit monoclonal (D12B11)
  • immunocytochemistry; human
  • western blot; rat
Cell Signaling Technology ATG7 antibody (Cell Signaling, 8558) was used in immunocytochemistry on human samples and in western blot on rat samples . Toxicol Lett (2015) ncbi
rabbit monoclonal (D12B11)
  • immunoprecipitation; human; fig 2a
  • western blot; human; fig 2a
Cell Signaling Technology ATG7 antibody (Cell Signaling Technology, 8558) was used in immunoprecipitation on human samples (fig 2a) and in western blot on human samples (fig 2a). Autophagy (2016) ncbi
rabbit monoclonal (D12B11)
  • western blot; fruit fly
In order to investigate the role of O-GlcNAcylation in autophagy, Cell Signaling Technology ATG7 antibody (Cell Signaling, 8558) was used in western blot on fruit fly samples . Cell Mol Life Sci (2015) ncbi
rabbit monoclonal (D12B11)
  • western blot; rat; loading ...; fig 5a
Cell Signaling Technology ATG7 antibody (Cell Signaling, 8558) was used in western blot on rat samples (fig 5a). PLoS ONE (2015) ncbi
rabbit monoclonal (D12B11)
  • western blot; rat; 1:1000
Cell Signaling Technology ATG7 antibody (Cell Signaling Technology, 8558) was used in western blot on rat samples at 1:1000. Neurobiol Dis (2015) ncbi
rabbit monoclonal (D12B11)
  • western blot; rat; fig 1h
Cell Signaling Technology ATG7 antibody (Sigma-Aldrich, 8558) was used in western blot on rat samples (fig 1h). Sci Rep (2015) ncbi
rabbit monoclonal (D12B11)
  • western blot; human; loading ...; fig 4c
Cell Signaling Technology ATG7 antibody (Cell Signaling Technology, 8558) was used in western blot on human samples (fig 4c). Autophagy (2015) ncbi
rabbit monoclonal (D12B11)
  • western blot; human; 1:1000
Cell Signaling Technology ATG7 antibody (Cell Signaling Technology, 8558) was used in western blot on human samples at 1:1000. Cancer Lett (2015) ncbi
rabbit monoclonal (D12B11)
  • western blot; human; 1:1000; fig 4
Cell Signaling Technology ATG7 antibody (Cell Signaling, 8558) was used in western blot on human samples at 1:1000 (fig 4). Nat Cell Biol (2014) ncbi
rabbit monoclonal (D12B11)
  • western blot; human
Cell Signaling Technology ATG7 antibody (Cell Signaling Technology, 8558) was used in western blot on human samples . Autophagy (2014) ncbi
Articles Reviewed
  1. Vera Ramirez L, Vodnala S, Nini R, Hunter K, Green J. Autophagy promotes the survival of dormant breast cancer cells and metastatic tumour recurrence. Nat Commun. 2018;9:1944 pubmed publisher
  2. Quaranta V, Rainer C, Nielsen S, Raymant M, Ahmed M, Engle D, et al. Macrophage-Derived Granulin Drives Resistance to Immune Checkpoint Inhibition in Metastatic Pancreatic Cancer. Cancer Res. 2018;78:4253-4269 pubmed publisher
  3. Ng P, Li J, Jeong K, Shao S, Chen H, Tsang Y, et al. Systematic Functional Annotation of Somatic Mutations in Cancer. Cancer Cell. 2018;33:450-462.e10 pubmed publisher
  4. Viswanath P, Radoul M, Izquierdo Garcia J, Ong W, Luchman H, Cairncross J, et al. 2-Hydroxyglutarate-Mediated Autophagy of the Endoplasmic Reticulum Leads to an Unusual Downregulation of Phospholipid Biosynthesis in Mutant IDH1 Gliomas. Cancer Res. 2018;78:2290-2304 pubmed publisher
  5. Guo H, Chitiprolu M, Roncevic L, Javalet C, Hemming F, Trung M, et al. Atg5 Disassociates the V1V0-ATPase to Promote Exosome Production and Tumor Metastasis Independent of Canonical Macroautophagy. Dev Cell. 2017;43:716-730.e7 pubmed publisher
  6. Merrill N, Schipper J, Karnes J, Kauffman A, Martin K, Mackeigan J. PI3K-C2? knockdown decreases autophagy and maturation of endocytic vesicles. PLoS ONE. 2017;12:e0184909 pubmed publisher
  7. Goodwin J, Dowdle W, Dejesus R, Wang Z, Bergman P, Kobylarz M, et al. Autophagy-Independent Lysosomal Targeting Regulated by ULK1/2-FIP200 and ATG9. Cell Rep. 2017;20:2341-2356 pubmed publisher
  8. Jung J, Nayak A, Schaeffer V, Starzetz T, Kirsch A, Muller S, et al. Multiplex image-based autophagy RNAi screening identifies SMCR8 as ULK1 kinase activity and gene expression regulator. elife. 2017;6: pubmed publisher
  9. Wang Q, Wu S, Zhu H, Ding Y, Dai X, Ouyang C, et al. Deletion of PRKAA triggers mitochondrial fission by inhibiting the autophagy-dependent degradation of DNM1L. Autophagy. 2017;13:404-422 pubmed publisher
  10. Yang M, Wang B, Miao L, Xu X, He X. Autophagy is involved in aldosterone‑induced mesangial cell proliferation. Mol Med Rep. 2016;14:4638-4642 pubmed publisher
  11. Gómez Puerto M, Verhagen L, Braat A, Lam E, Coffer P, Lorenowicz M. Activation of autophagy by FOXO3 regulates redox homeostasis during osteogenic differentiation. Autophagy. 2016;12:1804-1816 pubmed
  12. Gao Y, Liu Y, Hong L, Yang Z, Cai X, Chen X, et al. Golgi-associated LC3 lipidation requires V-ATPase in noncanonical autophagy. Cell Death Dis. 2016;7:e2330 pubmed publisher
  13. Li W, Jin D, Hata M, Takai S, Yamanishi K, Shen W, et al. Dysfunction of mitochondria and deformed gap junctions in the heart of IL-18-deficient mice. Am J Physiol Heart Circ Physiol. 2016;311:H313-25 pubmed publisher
  14. Wohlgemuth S, Ramirez Lee Y, Tao S, Monteiro A, Ahmed B, Dahl G. Short communication: Effect of heat stress on markers of autophagy in the mammary gland during the dry period. J Dairy Sci. 2016;99:4875-4880 pubmed publisher
  15. Kumar R, Narasimhan M, Shanmugam G, Hong J, Devarajan A, Palaniappan S, et al. Abrogation of Nrf2 impairs antioxidant signaling and promotes atrial hypertrophy in response to high-intensity exercise stress. J Transl Med. 2016;14:86 pubmed publisher
  16. Son S, Cha M, Choi H, Kang S, Choi H, Lee M, et al. Insulin-degrading enzyme secretion from astrocytes is mediated by an autophagy-based unconventional secretory pathway in Alzheimer disease. Autophagy. 2016;12:784-800 pubmed publisher
  17. Wu B, Yu L, Wang Y, Wang H, Li C, Yin Y, et al. Aldehyde dehydrogenase 2 activation in aged heart improves the autophagy by reducing the carbonyl modification on SIRT1. Oncotarget. 2016;7:2175-88 pubmed publisher
  18. Xie C, Ginet V, Sun Y, Koike M, Zhou K, Li T, et al. Neuroprotection by selective neuronal deletion of Atg7 in neonatal brain injury. Autophagy. 2016;12:410-23 pubmed publisher
  19. Dou Z, Xu C, Donahue G, Shimi T, Pan J, Zhu J, et al. Autophagy mediates degradation of nuclear lamina. Nature. 2015;527:105-9 pubmed publisher
  20. Kharaziha P, Chioureas D, Baltatzis G, Fonseca P, Rodriguez P, Gogvadze V, et al. Sorafenib-induced defective autophagy promotes cell death by necroptosis. Oncotarget. 2015;6:37066-82 pubmed publisher
  21. Barbone D, Follo C, Echeverry N, Gerbaudo V, Klabatsa A, Bueno R, et al. Autophagy Correlates with the Therapeutic Responsiveness of Malignant Pleural Mesothelioma in 3D Models. PLoS ONE. 2015;10:e0134825 pubmed publisher
  22. Yang S, Lin H, Chang V, Chen C, Liu Y, Wang J, et al. Lovastatin overcomes gefitinib resistance through TNF-α signaling in human cholangiocarcinomas with different LKB1 statuses in vitro and in vivo. Oncotarget. 2015;6:23857-73 pubmed
  23. Felzen V, Hiebel C, Koziollek Drechsler I, Reißig S, Wolfrum U, Kögel D, et al. Estrogen receptor α regulates non-canonical autophagy that provides stress resistance to neuroblastoma and breast cancer cells and involves BAG3 function. Cell Death Dis. 2015;6:e1812 pubmed publisher
  24. Zhang L, Wang H, Ding K, Xu J. FTY720 induces autophagy-related apoptosis and necroptosis in human glioblastoma cells. Toxicol Lett. 2015;236:43-59 pubmed publisher
  25. Luo T, Fu J, Xu A, Su B, Ren Y, Li N, et al. PSMD10/gankyrin induces autophagy to promote tumor progression through cytoplasmic interaction with ATG7 and nuclear transactivation of ATG7 expression. Autophagy. 2016;12:1355-71 pubmed publisher
  26. Park S, Lee Y, Pak J, Kim H, Choi H, Kim J, et al. O-GlcNAc modification is essential for the regulation of autophagy in Drosophila melanogaster. Cell Mol Life Sci. 2015;72:3173-83 pubmed publisher
  27. McMillan E, Paré M, Baechler B, Graham D, Rush J, Quadrilatero J. Autophagic signaling and proteolytic enzyme activity in cardiac and skeletal muscle of spontaneously hypertensive rats following chronic aerobic exercise. PLoS ONE. 2015;10:e0119382 pubmed publisher
  28. Harris White M, Ferbas K, Johnson M, Eslami P, Poteshkina A, Venkova K, et al. A cell-penetrating ester of the neural metabolite lanthionine ketimine stimulates autophagy through the mTORC1 pathway: Evidence for a mechanism of action with pharmacological implications for neurodegenerative pathologies. Neurobiol Dis. 2015;84:60-8 pubmed publisher
  29. Ma Y, Yang H, Xu L, Huang Y, Dai H, KANG X. Testosterone regulates the autophagic clearance of androgen binding protein in rat Sertoli cells. Sci Rep. 2015;5:8894 pubmed publisher
  30. Sanjurjo L, Amézaga N, Aran G, Naranjo Gómez M, Arias L, Armengol C, et al. The human CD5L/AIM-CD36 axis: A novel autophagy inducer in macrophages that modulates inflammatory responses. Autophagy. 2015;11:487-502 pubmed publisher
  31. Zanotto Filho A, Braganhol E, Klafke K, Figueiró F, Terra S, Paludo F, et al. Autophagy inhibition improves the efficacy of curcumin/temozolomide combination therapy in glioblastomas. Cancer Lett. 2015;358:220-31 pubmed publisher
  32. Dowdle W, Nyfeler B, Nagel J, Elling R, Liu S, Triantafellow E, et al. Selective VPS34 inhibitor blocks autophagy and uncovers a role for NCOA4 in ferritin degradation and iron homeostasis in vivo. Nat Cell Biol. 2014;16:1069-79 pubmed publisher
  33. Zhan Z, Xie X, Cao H, Zhou X, Zhang X, Fan H, et al. Autophagy facilitates TLR4- and TLR3-triggered migration and invasion of lung cancer cells through the promotion of TRAF6 ubiquitination. Autophagy. 2014;10:257-68 pubmed publisher