This is a Validated Antibody Database (VAD) review about cow AKT1, based on 1153 published articles (read how Labome selects the articles), using AKT1 antibody in all methods. It is aimed to help Labome visitors find the most suited AKT1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
AKT1 synonym: AKT; RAC-alpha serine/threonine-protein kinase; PKB alpha; RAC-PK-alpha; protein kinase B alpha

Abcam
rabbit polyclonal
  • western blot; human; loading ...; fig 5d
Abcam AKT1 antibody (Abcam, ab8932) was used in western blot on human samples (fig 5d). Lab Invest (2017) ncbi
rabbit polyclonal
  • western blot; human; fig 6
Abcam AKT1 antibody (Abcam, ab8932) was used in western blot on human samples (fig 6). Oncotarget (2016) ncbi
rabbit polyclonal
  • immunohistochemistry - paraffin section; human; fig 1f-j
  • western blot; human; fig 4b
Abcam AKT1 antibody (Abcam, ab8932) was used in immunohistochemistry - paraffin section on human samples (fig 1f-j) and in western blot on human samples (fig 4b). Oncotarget (2015) ncbi
rabbit polyclonal
  • immunohistochemistry - paraffin section; human; fig 1
Abcam AKT1 antibody (Abcam, ab8932) was used in immunohistochemistry - paraffin section on human samples (fig 1). Oncotarget (2015) ncbi
rabbit polyclonal
  • immunohistochemistry - frozen section; mouse; 1:100
Abcam AKT1 antibody (Abcam, ab64148) was used in immunohistochemistry - frozen section on mouse samples at 1:100. Nat Neurosci (2015) ncbi
Proteintech Group
rabbit polyclonal
  • western blot; human; 1:2000; loading ...; fig s2a
  • western blot; mouse; 1:2000; loading ...; fig s2b
Proteintech Group AKT1 antibody (Proteintech, 10176-2-AP) was used in western blot on human samples at 1:2000 (fig s2a) and in western blot on mouse samples at 1:2000 (fig s2b). J Cell Sci (2019) ncbi
rabbit polyclonal
  • western blot; human; 1:1000; fig 5
Proteintech Group AKT1 antibody (Proteintech, 10176-2-AP) was used in western blot on human samples at 1:1000 (fig 5). Sci Rep (2016) ncbi
rabbit polyclonal
  • western blot; pig; loading ...; fig 6a
Proteintech Group AKT1 antibody (Proteintech Group, 10176-2-AP) was used in western blot on pig samples (fig 6a). PLoS ONE (2015) ncbi
MilliporeSigma
mouse monoclonal (PKB-175)
  • western blot; human; fig 3
In order to study how all-trans retinoic acid modulates the ERK signaling pathway, MilliporeSigma AKT1 antibody (Sigma-Aldrich, P-2482) was used in western blot on human samples (fig 3). Biomed Res Int (2015) ncbi
Cell Signaling Technology
rabbit polyclonal
  • western blot; human; loading ...; fig 10a
Cell Signaling Technology AKT1 antibody (cell signaling technologies, 9271) was used in western blot on human samples (fig 10a). Front Genet (2019) ncbi
rabbit monoclonal (D9E)
  • western blot; human; 1:1000; loading ...; fig 6h
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 4060) was used in western blot on human samples at 1:1000 (fig 6h). Cancer Discov (2019) ncbi
rabbit monoclonal (D9E)
  • western blot; human; 1:1000; loading ...; fig 2a
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on human samples at 1:1000 (fig 2a). Int J Biol Sci (2019) ncbi
rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig 2f
Cell Signaling Technology AKT1 antibody (CST, 9271S) was used in western blot on human samples at 1:1000 (fig 2f). Nat Commun (2019) ncbi
rabbit monoclonal (D9E)
  • immunohistochemistry - paraffin section; mouse; 1:100; loading ...; fig 4c
Cell Signaling Technology AKT1 antibody (CST, 4060) was used in immunohistochemistry - paraffin section on mouse samples at 1:100 (fig 4c). Science (2019) ncbi
rabbit polyclonal
  • western blot; human; loading ...; fig s2i
  • western blot; mouse; loading ...; fig 2e
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 9271) was used in western blot on human samples (fig s2i) and in western blot on mouse samples (fig 2e). Science (2019) ncbi
rabbit monoclonal (D9E)
  • western blot; human; 1:1000; loading ...; fig 3c
Cell Signaling Technology AKT1 antibody (Cell Signalling Technology, 4060) was used in western blot on human samples at 1:1000 (fig 3c). EMBO Mol Med (2019) ncbi
rabbit monoclonal (D9E)
  • flow cytometry; human; loading ...; fig 1d
  • western blot; human; loading ...; fig 1c
Cell Signaling Technology AKT1 antibody (Cell Signaling, D9E) was used in flow cytometry on human samples (fig 1d) and in western blot on human samples (fig 1c). Front Immunol (2019) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; 1:1000; loading ...; fig 6s1c
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on mouse samples at 1:1000 (fig 6s1c). elife (2019) ncbi
rabbit polyclonal
  • western blot; human; loading ...; fig 7b
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on human samples (fig 7b). Cell (2019) ncbi
rabbit monoclonal (D9E)
  • western blot; human; 1:500; loading ...; fig 3f
Cell Signaling Technology AKT1 antibody (cell signaling, 4060) was used in western blot on human samples at 1:500 (fig 3f). Sci Rep (2019) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; 1:1000; loading ...; fig 5a
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on mouse samples at 1:1000 (fig 5a). Neurobiol Dis (2019) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; 1:4000; loading ...; fig s1e
Cell Signaling Technology AKT1 antibody (Cell Signalling, 4060) was used in western blot on mouse samples at 1:4000 (fig s1e). Science (2019) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; 1:2000; loading ...; fig s2b
  • western blot; human; 1:2000; loading ...; fig s2a
Cell Signaling Technology AKT1 antibody (CST, 4060S) was used in western blot on mouse samples at 1:2000 (fig s2b) and in western blot on human samples at 1:2000 (fig s2a). J Cell Sci (2019) ncbi
rabbit monoclonal (D9E)
  • western blot; human; loading ...; fig 2l
Cell Signaling Technology AKT1 antibody (CST, 4060) was used in western blot on human samples (fig 2l). Theranostics (2019) ncbi
rabbit polyclonal
  • western blot; mouse; 1:1000; loading ...; fig 6i
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on mouse samples at 1:1000 (fig 6i). Aging Cell (2019) ncbi
rabbit monoclonal (D9E)
  • western blot; human; loading ...; fig 6b
Cell Signaling Technology AKT1 antibody (Cell signaling, 4060) was used in western blot on human samples (fig 6b). elife (2019) ncbi
rabbit polyclonal
  • western blot; human; loading ...; fig 2a
Cell Signaling Technology AKT1 antibody (CST, 9271) was used in western blot on human samples (fig 2a). Cell Death Dis (2019) ncbi
rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig 5b
Cell Signaling Technology AKT1 antibody (CST, 9271) was used in western blot on human samples at 1:1000 (fig 5b). Nat Commun (2019) ncbi
rabbit polyclonal
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used . Cell (2019) ncbi
rabbit polyclonal
  • western blot; human; loading ...; fig 2b
  • western blot; mouse; loading ...; fig 7c
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 9271) was used in western blot on human samples (fig 2b) and in western blot on mouse samples (fig 7c). J Clin Invest (2019) ncbi
rabbit monoclonal (D9E)
  • western blot; human; 1:1000; loading ...; fig 2d
  • western blot; mouse; 1:1000; loading ...; fig 2d
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060S) was used in western blot on human samples at 1:1000 (fig 2d) and in western blot on mouse samples at 1:1000 (fig 2d). elife (2019) ncbi
rabbit monoclonal (D9E)
  • western blot; human; loading ...; fig s1d
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on human samples (fig s1d). Science (2018) ncbi
rabbit monoclonal (D9E)
  • immunohistochemistry; mouse; loading ...; fig 6b
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in immunohistochemistry on mouse samples (fig 6b). Cell Rep (2018) ncbi
rabbit monoclonal (D9E)
  • western blot; human; loading ...; fig 1c
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on human samples (fig 1c). J Biol Chem (2019) ncbi
rabbit polyclonal
  • western blot; mouse; loading ...; fig s6f
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on mouse samples (fig s6f). Cell Rep (2018) ncbi
rabbit monoclonal (D9E)
  • western blot; rat; 1:1000; loading ...; fig 3b, 4f, 5f
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on rat samples at 1:1000 (fig 3b, 4f, 5f). Br J Pharmacol (2019) ncbi
rabbit polyclonal
  • western blot; human; loading ...; fig 3a
  • western blot; mouse; loading ...; fig 2d
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271S) was used in western blot on human samples (fig 3a) and in western blot on mouse samples (fig 2d). Oncogene (2019) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; loading ...; fig s4c, s7c
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on mouse samples (fig s4c, s7c). Cell (2018) ncbi
rabbit monoclonal (D9E)
  • western blot; human; 1:1000; loading ...; fig 4a
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on human samples at 1:1000 (fig 4a). Nat Commun (2018) ncbi
rabbit monoclonal (D9E)
  • western blot; human; loading ...; fig s7f
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on human samples (fig s7f). Science (2018) ncbi
rabbit monoclonal (D9E)
  • western blot; human; 1:2000; loading ...; fig 6c
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on human samples at 1:2000 (fig 6c). Cancer Sci (2019) ncbi
rabbit polyclonal
  • western blot; mouse; loading ...; fig 3e, 4e
  • western blot; rat; loading ...; fig 1d
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on mouse samples (fig 3e, 4e) and in western blot on rat samples (fig 1d). Sci Rep (2018) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; 1:2000; loading ...; fig 5a
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on mouse samples at 1:2000 (fig 5a). Front Aging Neurosci (2018) ncbi
rabbit polyclonal
  • immunocytochemistry; mouse; 1:800; loading ...; fig s6a
Cell Signaling Technology AKT1 antibody (cell signaling, 9271) was used in immunocytochemistry on mouse samples at 1:800 (fig s6a). Nat Commun (2018) ncbi
rabbit polyclonal
  • immunohistochemistry - paraffin section; human; loading ...; fig s1b
  • western blot; human; loading ...; fig s1c
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in immunohistochemistry - paraffin section on human samples (fig s1b) and in western blot on human samples (fig s1c). Science (2018) ncbi
rabbit monoclonal (D9E)
  • western blot; human; loading ...; fig s10d, s10g
  • western blot; mouse; loading ...; fig s10c
Cell Signaling Technology AKT1 antibody (Cell Signaling, D9E) was used in western blot on human samples (fig s10d, s10g) and in western blot on mouse samples (fig s10c). Science (2018) ncbi
rabbit monoclonal (D9E)
  • western blot; human; 1:1000; loading ...; fig 3c
Cell Signaling Technology AKT1 antibody (Cell Signaling, 5012) was used in western blot on human samples at 1:1000 (fig 3c). Cell Death Dis (2018) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; loading ...; fig 8a
Cell Signaling Technology AKT1 antibody (cst, 4060S) was used in western blot on mouse samples (fig 8a). J Exp Med (2018) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; loading ...; fig 5b
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on mouse samples (fig 5b). Blood (2018) ncbi
rabbit monoclonal (D9E)
  • western blot; human; loading ...; fig 3e
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 4060) was used in western blot on human samples (fig 3e). Cell Metab (2019) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; 1:1000; loading ...; fig 6c
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on mouse samples at 1:1000 (fig 6c). Nat Commun (2018) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; loading ...; fig 3c
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 4060S) was used in western blot on mouse samples (fig 3c). Cell Rep (2018) ncbi
rabbit polyclonal
  • western blot; human; loading ...; fig 7c
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 9271) was used in western blot on human samples (fig 7c). J Clin Invest (2018) ncbi
rabbit polyclonal
  • western blot; human; loading ...; fig 6c
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on human samples (fig 6c). J Autoimmun (2018) ncbi
rabbit monoclonal (D9E)
  • flow cytometry; mouse; 1:50; loading ...; fig 6a
Cell Signaling Technology AKT1 antibody (eBiosciences, D9E) was used in flow cytometry on mouse samples at 1:50 (fig 6a). J Exp Med (2018) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; loading ...; fig s3a
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 4060) was used in western blot on mouse samples (fig s3a). Immunity (2018) ncbi
rabbit polyclonal
  • western blot; mouse; 1:1000; loading ...; fig 4a
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on mouse samples at 1:1000 (fig 4a). EMBO J (2018) ncbi
rabbit polyclonal
  • western blot; mouse; 1:1000; loading ...; fig 5a
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on mouse samples at 1:1000 (fig 5a). Nat Commun (2018) ncbi
rabbit polyclonal
  • western blot; mouse; loading ...; fig 8c
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271s) was used in western blot on mouse samples (fig 8c). J Cell Mol Med (2018) ncbi
rabbit polyclonal
  • western blot; mouse; loading ...; fig 4b
Cell Signaling Technology AKT1 antibody (Cell signaling, 9271) was used in western blot on mouse samples (fig 4b). Cell Physiol Biochem (2018) ncbi
rabbit polyclonal
  • western blot; mouse; loading ...; fig s4c
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 9271s) was used in western blot on mouse samples (fig s4c). PLoS Biol (2018) ncbi
rabbit monoclonal (D9E)
  • western blot; human; loading ...; fig s1b
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 4060) was used in western blot on human samples (fig s1b). Autophagy (2018) ncbi
rabbit monoclonal (D9E)
  • western blot; human; 1:1000; loading ...; fig 3b
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060S) was used in western blot on human samples at 1:1000 (fig 3b). Nature (2018) ncbi
rabbit monoclonal (D9E)
  • western blot; human; loading ...; fig 2d
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 4060) was used in western blot on human samples (fig 2d). Proc Natl Acad Sci U S A (2018) ncbi
rabbit polyclonal
  • western blot; human; loading ...; fig 4f
  • western blot; mouse; loading ...; fig 2a, s8h, s14e, s15f
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on human samples (fig 4f) and in western blot on mouse samples (fig 2a, s8h, s14e, s15f). Nat Med (2018) ncbi
rabbit polyclonal
  • flow cytometry; mouse; 1:100-1:200; loading ...; fig s4d
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in flow cytometry on mouse samples at 1:100-1:200 (fig s4d). Cell Stem Cell (2018) ncbi
rabbit monoclonal (D9E)
  • western blot; human; fig 3a
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on human samples (fig 3a). J Exp Med (2018) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; fig 3a
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on mouse samples (fig 3a). FASEB J (2018) ncbi
rabbit monoclonal (D9E)
  • western blot; human; 1:1000; loading ...; fig 5a
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060S) was used in western blot on human samples at 1:1000 (fig 5a). Biosci Rep (2018) ncbi
rabbit monoclonal (D9E)
  • western blot; rat; 1:2000; loading ...; fig 4b
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on rat samples at 1:2000 (fig 4b). EMBO J (2018) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; 1:2000; loading ...; fig 3f
Cell Signaling Technology AKT1 antibody (CST, 4060) was used in western blot on mouse samples at 1:2000 (fig 3f). J Biol Chem (2018) ncbi
rabbit polyclonal
  • western blot; mouse; loading ...; fig 3c
Cell Signaling Technology AKT1 antibody (Cell Signaling Technologies, 9271) was used in western blot on mouse samples (fig 3c). Cell Death Dis (2018) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; fig 3a
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on mouse samples (fig 3a). Nat Commun (2018) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; 1:2000; loading ...; fig 5c
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on mouse samples at 1:2000 (fig 5c). J Exp Med (2018) ncbi
rabbit monoclonal (D9E)
  • western blot; human; loading ...; fig s2f
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on human samples (fig s2f). Science (2018) ncbi
rabbit monoclonal (D9E)
  • western blot; human; loading ...; fig 6f
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 4060) was used in western blot on human samples (fig 6f). Cell (2018) ncbi
rabbit monoclonal (D9E)
  • immunohistochemistry - paraffin section; human; loading ...; fig 4d
  • western blot; human; loading ...; fig 1d
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in immunohistochemistry - paraffin section on human samples (fig 4d) and in western blot on human samples (fig 1d). J Exp Clin Cancer Res (2018) ncbi
rabbit polyclonal
  • other; human; loading ...; fig 4c
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in other on human samples (fig 4c). Cancer Cell (2018) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; loading ...; fig 3e
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on mouse samples (fig 3e). J Clin Invest (2018) ncbi
rabbit monoclonal (D9E)
  • western blot; human; 1:1000; loading ...; fig 1e
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on human samples at 1:1000 (fig 1e). Science (2018) ncbi
rabbit monoclonal (D9E)
  • western blot; human; loading ...; fig 9d
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on human samples (fig 9d). J Cell Biol (2018) ncbi
rabbit polyclonal
  • western blot; mouse; loading ...; fig s7a
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 9271) was used in western blot on mouse samples (fig s7a). Biol Open (2018) ncbi
rabbit polyclonal
  • western blot; human; loading ...; fig 5b
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on human samples (fig 5b). Biochim Biophys Acta Mol Basis Dis (2018) ncbi
rabbit monoclonal (D9E)
  • immunohistochemistry - paraffin section; human; fig 7b
  • western blot; human; fig 3b
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in immunohistochemistry - paraffin section on human samples (fig 7b) and in western blot on human samples (fig 3b). Cell (2018) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; fig s2d
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on mouse samples (fig s2d). Nature (2018) ncbi
rabbit polyclonal
  • western blot; rat; fig 3a
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on rat samples (fig 3a). Immunol Cell Biol (2018) ncbi
rabbit monoclonal (D9E)
  • western blot; human; loading ...; fig s7d
Cell Signaling Technology AKT1 antibody (Cell Signaling, D9E) was used in western blot on human samples (fig s7d). Proc Natl Acad Sci U S A (2018) ncbi
rabbit monoclonal (D9E)
  • western blot; human; loading ...; fig 6e
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 4060) was used in western blot on human samples (fig 6e). Oncogene (2018) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; fig 1c
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on mouse samples (fig 1c). Cell (2018) ncbi
rabbit monoclonal (D9E)
  • western blot; human; fig 3b
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060S) was used in western blot on human samples (fig 3b). Cell (2018) ncbi
rabbit monoclonal (D9E)
  • western blot; human; 1:1000; fig s3f
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on human samples at 1:1000 (fig s3f). Nature (2018) ncbi
rabbit monoclonal (D9E)
  • western blot; human; loading ...; fig 3h, 3i
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060S) was used in western blot on human samples (fig 3h, 3i). J Exp Med (2018) ncbi
rabbit polyclonal
  • western blot; human; fig 2b
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271S) was used in western blot on human samples (fig 2b). Cell (2018) ncbi
rabbit polyclonal
  • western blot; mouse; fig 6c
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on mouse samples (fig 6c). Neurobiol Dis (2018) ncbi
rabbit monoclonal (D9E)
  • western blot; human; 1:1000; loading ...; fig 6d
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on human samples at 1:1000 (fig 6d). Nat Commun (2017) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; fig s1j
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on mouse samples (fig s1j). Cell (2018) ncbi
rabbit polyclonal
  • western blot; mouse; loading ...; fig 1a
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on mouse samples (fig 1a). Immunity (2017) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; 1:1000; loading ...; fig 6b
Cell Signaling Technology AKT1 antibody (Cell Signaling, D9E) was used in western blot on mouse samples at 1:1000 (fig 6b). Cell Death Dis (2017) ncbi
rabbit monoclonal (D9E)
  • western blot; human; loading ...; fig 7b
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 4060) was used in western blot on human samples (fig 7b). J Virol (2018) ncbi
rabbit polyclonal
  • western blot; human; loading ...; fig 2a
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on human samples (fig 2a). Cancer Res (2018) ncbi
rabbit monoclonal (D9E)
  • western blot; human; fig 6a
Cell Signaling Technology AKT1 antibody (Cell signaling, 4060) was used in western blot on human samples (fig 6a). Oncotarget (2017) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; loading ...; fig 1d
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on mouse samples (fig 1d). Oncotarget (2017) ncbi
rabbit monoclonal (D9E)
  • flow cytometry; mouse; loading ...; fig 4a
Cell Signaling Technology AKT1 antibody (Cell Signaling, D9E) was used in flow cytometry on mouse samples (fig 4a). J Clin Invest (2018) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; 1:1000; loading ...; fig 4a
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 4060) was used in western blot on mouse samples at 1:1000 (fig 4a). J Lipid Res (2018) ncbi
rabbit polyclonal
  • western blot; mouse; fig 5a
Cell Signaling Technology AKT1 antibody (Cell signaling, 9271) was used in western blot on mouse samples (fig 5a). Immunity (2017) ncbi
rabbit monoclonal (D9E)
  • western blot; human; loading ...; fig 1f
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on human samples (fig 1f). Autophagy (2018) ncbi
rabbit monoclonal (D9E)
  • western blot; human; loading ...; fig 2e
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on human samples (fig 2e). Nature (2017) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; loading ...; fig 2a
Cell Signaling Technology AKT1 antibody (CST, 4060) was used in western blot on mouse samples (fig 2a). Mol Neurobiol (2018) ncbi
rabbit monoclonal (D9E)
  • western blot; human; loading ...; fig 2c
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060L) was used in western blot on human samples (fig 2c). Breast Cancer Res Treat (2018) ncbi
rabbit polyclonal
  • western blot; mouse; 1:1000; loading ...; fig 4b
Cell Signaling Technology AKT1 antibody (Cell Signalling, 9271) was used in western blot on mouse samples at 1:1000 (fig 4b). J Endocrinol (2018) ncbi
rabbit polyclonal
  • western blot; human; loading ...; fig s4a
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 9271) was used in western blot on human samples (fig s4a). Mol Biol Cell (2018) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; 1:3000; loading ...; fig 4g
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 4060) was used in western blot on mouse samples at 1:3000 (fig 4g). Diabetes (2018) ncbi
rabbit monoclonal (D9E)
  • western blot; human; loading ...; fig 4
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 4060) was used in western blot on human samples (fig 4). Cell Biol Int (2017) ncbi
rabbit polyclonal
  • western blot; mouse; loading ...; fig 4a
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on mouse samples (fig 4a). J Clin Invest (2017) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; loading ...; fig s10c
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on mouse samples (fig s10c). Proc Natl Acad Sci U S A (2017) ncbi
rabbit polyclonal
  • western blot; mouse; 1:3000; loading ...; fig 5m
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 9271) was used in western blot on mouse samples at 1:3000 (fig 5m). Endocrinology (2018) ncbi
rabbit polyclonal
  • western blot; human; loading ...; fig 1c
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on human samples (fig 1c). Oncotarget (2017) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; 1:1000; loading ...; fig 4e
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 4060) was used in western blot on mouse samples at 1:1000 (fig 4e). Sci Transl Med (2017) ncbi
rabbit monoclonal (D9E)
  • western blot; human; 1:1000; loading ...; fig s2a
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on human samples at 1:1000 (fig s2a). Nat Med (2017) ncbi
rabbit polyclonal
  • western blot; rat; 1:1000; loading ...; fig 7c
Cell Signaling Technology AKT1 antibody (Cell signaling, 9271) was used in western blot on rat samples at 1:1000 (fig 7c). Neuropharmacology (2018) ncbi
rabbit polyclonal
  • western blot; mouse; loading ...; fig 2a
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on mouse samples (fig 2a). J Nutr Biochem (2017) ncbi
rabbit monoclonal (D9E)
  • western blot; human; fig 5a
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on human samples (fig 5a). Inflammation (2018) ncbi
rabbit monoclonal (D9E)
  • western blot; human; loading ...; fig 7b
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on human samples (fig 7b). Clin Cancer Res (2018) ncbi
rabbit polyclonal
  • western blot; mouse; 1:1000; loading ...; fig 4a
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on mouse samples at 1:1000 (fig 4a). PLoS ONE (2017) ncbi
rabbit polyclonal
  • western blot; human; loading ...; fig 3d
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on human samples (fig 3d). Oncogene (2018) ncbi
rabbit monoclonal (D9E)
  • western blot; human; 1:1000; loading ...; fig 6h
  • western blot; mouse; 1:1000; loading ...; fig 6h
In order to study induction of cell death by low frequency magnetic fields, Cell Signaling Technology AKT1 antibody (Cell Signalling, 4060) was used in western blot on human samples at 1:1000 (fig 6h) and in western blot on mouse samples at 1:1000 (fig 6h). Sci Rep (2017) ncbi
rabbit polyclonal
  • western blot; human; loading ...; fig 13e
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on human samples (fig 13e). J Clin Invest (2017) ncbi
rabbit monoclonal (D9E)
  • western blot; human; loading ...; fig 3d
  • western blot; mouse; loading ...; fig 2b
In order to research the role of endothelial APLNR in the regulation of tissue fatty acid uptake, Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on human samples (fig 3d) and in western blot on mouse samples (fig 2b). Sci Transl Med (2017) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; loading ...; fig 4a, 4b
  • western blot; human; loading ...; fig 4b
Cell Signaling Technology AKT1 antibody (Cell Signaling, D9E) was used in western blot on mouse samples (fig 4a, 4b) and in western blot on human samples (fig 4b). Oncogene (2018) ncbi
rabbit monoclonal (D9E)
  • immunohistochemistry; mouse; loading ...; fig s5c
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in immunohistochemistry on mouse samples (fig s5c). Science (2017) ncbi
rabbit polyclonal
  • western blot; mouse; 1:1000; loading ...; fig 3c
Cell Signaling Technology AKT1 antibody (cell signaling, 9271) was used in western blot on mouse samples at 1:1000 (fig 3c). Oncogene (2017) ncbi
rabbit monoclonal (D9E)
  • western blot; human; fig 4a
Cell Signaling Technology AKT1 antibody (Cell Signalling Technology, 4060) was used in western blot on human samples (fig 4a). DNA Cell Biol (2017) ncbi
rabbit monoclonal (D9E)
  • western blot; human; loading ...; fig 9c
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on human samples (fig 9c). J Virol (2017) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; loading ...; fig s5g
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on mouse samples (fig s5g). J Clin Invest (2017) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; loading ...; fig s10a
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, D9E) was used in western blot on mouse samples (fig s10a). Sci Rep (2017) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; loading ...; fig 3
Cell Signaling Technology AKT1 antibody (Cell signaling technology, 4060) was used in western blot on mouse samples (fig 3). Physiol Rep (2017) ncbi
rabbit monoclonal (D9E)
  • western blot; human; loading ...; fig 1a
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on human samples (fig 1a). Mol Oncol (2017) ncbi
rabbit monoclonal (D9E)
  • western blot; human; loading ...; fig 3a
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on human samples (fig 3a). Mol Cell Biol (2017) ncbi
rabbit monoclonal (D9E)
  • immunohistochemistry - paraffin section; human; 1:100; loading ...; fig 6a
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 4060) was used in immunohistochemistry - paraffin section on human samples at 1:100 (fig 6a). Nat Commun (2017) ncbi
rabbit monoclonal (D9E)
  • western blot; human; 1:1000; loading ...; fig 8a
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 40602) was used in western blot on human samples at 1:1000 (fig 8a). Sci Rep (2017) ncbi
rabbit polyclonal
  • immunohistochemistry; mouse; 1:500; loading ...; fig 3
In order to research the role for BMP4 i mouse ureter development, Cell Signaling Technology AKT1 antibody (cell signalling, 9271) was used in immunohistochemistry on mouse samples at 1:500 (fig 3). Hum Mol Genet (2017) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; loading ...; fig 3a
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on mouse samples (fig 3a). Biochem Biophys Res Commun (2017) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; loading ...; fig 2f
Cell Signaling Technology AKT1 antibody (Cell signaling, 4060) was used in western blot on mouse samples (fig 2f). Cancer Res (2017) ncbi
rabbit monoclonal (D9E)
  • western blot; human; loading ...; fig 5
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on human samples (fig 5). Exp Neurol (2018) ncbi
rabbit polyclonal
  • western blot; mouse; 1:1000; fig 6d
In order to study the function of OPA1 in FGF21 secretion from muscle, Cell Signaling Technology AKT1 antibody (Cell signaling, 9271) was used in western blot on mouse samples at 1:1000 (fig 6d). EMBO J (2017) ncbi
rabbit polyclonal
  • western blot; dog; loading ...; fig s3a
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 9271) was used in western blot on dog samples (fig s3a). Oncogene (2017) ncbi
rabbit monoclonal (D9E)
  • western blot; human; 1:2000; loading ...; fig 6
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on human samples at 1:2000 (fig 6). Oncol Rep (2017) ncbi
rabbit monoclonal (D9E)
  • western blot; human; 1:2000; loading ...; fig 4h
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on human samples at 1:2000 (fig 4h). Nat Commun (2017) ncbi
rabbit monoclonal (D9E)
  • western blot; human; loading ...; fig s5f
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on human samples (fig s5f). Nat Commun (2017) ncbi
rabbit monoclonal (D9E)
  • western blot; human; fig 5c
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 4060) was used in western blot on human samples (fig 5c). Sci Adv (2017) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; loading ...; fig 3g
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 4060) was used in western blot on mouse samples (fig 3g). J Exp Med (2017) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; fig s10m
In order to investigate the effect of lymphatic endothelial S1P on mitochondrial function and naive T cell survival, Cell Signaling Technology AKT1 antibody (Cell Signaling, D9E) was used in western blot on mouse samples (fig s10m). Nature (2017) ncbi
rabbit monoclonal (D9E)
  • immunohistochemistry; mouse; loading ...; fig 6a
  • western blot; mouse; loading ...; fig 1e
Cell Signaling Technology AKT1 antibody (cell signalling, 4060) was used in immunohistochemistry on mouse samples (fig 6a) and in western blot on mouse samples (fig 1e). Mol Neurobiol (2018) ncbi
rabbit monoclonal (D9E)
  • western blot; human; loading ...; fig 1d
  • western blot; mouse; loading ...; fig 1j
Cell Signaling Technology AKT1 antibody (Cell signaling, 4060) was used in western blot on human samples (fig 1d) and in western blot on mouse samples (fig 1j). Nature (2017) ncbi
rabbit polyclonal
  • western blot; human; loading ...; fig 1e
In order to study the oncogenic role of ERK1 in glioma, Cell Signaling Technology AKT1 antibody (CST, 9271) was used in western blot on human samples (fig 1e). J Immunol (2017) ncbi
rabbit polyclonal
  • western blot; human; fig 1b
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on human samples (fig 1b). Proc Natl Acad Sci U S A (2017) ncbi
rabbit monoclonal (D9E)
  • immunohistochemistry; zebrafish ; loading ...; fig 3s1g
  • western blot; zebrafish ; loading ...; fig 3s1e
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 4060) was used in immunohistochemistry on zebrafish samples (fig 3s1g) and in western blot on zebrafish samples (fig 3s1e). elife (2017) ncbi
rabbit monoclonal (D9E)
  • western blot; human; loading ...; fig 7a
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on human samples (fig 7a). Oncotarget (2017) ncbi
rabbit monoclonal (D9E)
  • western blot; human; 1:500; loading ...; fig 5c
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on human samples at 1:500 (fig 5c). J Clin Endocrinol Metab (2017) ncbi
rabbit monoclonal (D9E)
  • western blot; rat; 1:1000; loading ...; fig 5c
In order to study the impact of diet and stress on adult rat behavior and hippocampal plasticity, Cell Signaling Technology AKT1 antibody (cell signalling, 4060) was used in western blot on rat samples at 1:1000 (fig 5c). Mol Neurobiol (2018) ncbi
rabbit polyclonal
  • western blot; mouse; 1:50; fig 5b
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on mouse samples at 1:50 (fig 5b). J Cell Biol (2017) ncbi
rabbit polyclonal
  • western blot; mouse; loading ...; fig 5c
Cell Signaling Technology AKT1 antibody (Cell signaling, 9271) was used in western blot on mouse samples (fig 5c). Cell Immunol (2017) ncbi
rabbit polyclonal
  • western blot; pig; loading ...; fig 5b
Cell Signaling Technology AKT1 antibody (Cell Signal, 9271) was used in western blot on pig samples (fig 5b). Oncotarget (2017) ncbi
rabbit monoclonal (D9E)
  • western blot; fruit fly; loading ...; fig 1j
  • western blot; human; loading ...; fig 1k
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060S) was used in western blot on fruit fly samples (fig 1j) and in western blot on human samples (fig 1k). Cell (2017) ncbi
rabbit monoclonal (D9E)
  • western blot; human; loading ...; fig 1a
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on human samples (fig 1a). Cancer Res (2017) ncbi
rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig 6a
In order to evaluate the regulation of Epstein-Barr virus-infected ARPE19 cell migration as a model of choroidal neovascularization, Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 9271) was used in western blot on human samples at 1:1000 (fig 6a). Exp Ther Med (2017) ncbi
rabbit monoclonal (D9E)
  • western blot; human; 1:1000; fig 4c
In order to measure the expressions of XCR1 mRNA breast cancer cell lines, Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060P) was used in western blot on human samples at 1:1000 (fig 4c). Breast Cancer (Dove Med Press) (2017) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; loading ...; fig 4b
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 4060) was used in western blot on mouse samples (fig 4b). elife (2017) ncbi
rabbit polyclonal
  • western blot; human; loading ...; fig 2
Cell Signaling Technology AKT1 antibody (cell signalling, 9271) was used in western blot on human samples (fig 2). Neoplasia (2017) ncbi
rabbit monoclonal (D9E)
  • immunohistochemistry - paraffin section; mouse; loading ...; fig 4c
  • western blot; mouse; loading ...; fig 4a
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 4060) was used in immunohistochemistry - paraffin section on mouse samples (fig 4c) and in western blot on mouse samples (fig 4a). J Cell Biochem (2017) ncbi
rabbit polyclonal
  • western blot; human; 1:500; loading ...; fig 3a
In order to elucidate the mechanism of Pin1 overexpression in hepatocellular carcinoma, Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 9271 S) was used in western blot on human samples at 1:500 (fig 3a). Sci Rep (2017) ncbi
rabbit monoclonal (D9E)
  • immunocytochemistry; mouse; 1:200; loading ...; fig s4a
  • western blot; mouse; 1:1000; loading ...; fig 2d, 2h
Cell Signaling Technology AKT1 antibody (Cell Signaling, D9E) was used in immunocytochemistry on mouse samples at 1:200 (fig s4a) and in western blot on mouse samples at 1:1000 (fig 2d, 2h). Nat Commun (2017) ncbi
rabbit monoclonal (D9E)
  • western blot; human; 1:500; loading ...; fig 3A
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060S) was used in western blot on human samples at 1:500 (fig 3A). Oncol Lett (2017) ncbi
rabbit monoclonal (D9E)
  • western blot; human; loading ...; fig 5a
In order to study the synergistic antitumor effect of simultaneously targeting CD47 and autophagy in non-small cell lung cancer, Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on human samples (fig 5a). Cancer Immunol Res (2017) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; loading ...; fig 6f
In order to clarify the mechanisms by which miR-21 contributes to oncogenesis, Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060s) was used in western blot on mouse samples (fig 6f). Oncogene (2017) ncbi
rabbit polyclonal
  • western blot; mouse; 1:1000; fig 7a
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on mouse samples at 1:1000 (fig 7a). Nat Commun (2017) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; 1:500; fig 7b
In order to examine the impact of the unfolded protein response in satellite cell homeostasis during regenerative myogenesis, Cell Signaling Technology AKT1 antibody (Cell signaling, 4060) was used in western blot on mouse samples at 1:500 (fig 7b). elife (2017) ncbi
rabbit monoclonal (D9E)
  • western blot; human; fig 6a
Cell Signaling Technology AKT1 antibody (Cell signaling, 4060) was used in western blot on human samples (fig 6a). Cancer Med (2017) ncbi
rabbit monoclonal (D9E)
  • western blot; human; fig 3c
Cell Signaling Technology AKT1 antibody (Cell signaling, 4060) was used in western blot on human samples (fig 3c). Mol Ther Nucleic Acids (2017) ncbi
rabbit monoclonal (D9E)
  • immunohistochemistry - paraffin section; mouse; loading ...; fig 7g
  • western blot; mouse; loading ...; fig 5a
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in immunohistochemistry - paraffin section on mouse samples (fig 7g) and in western blot on mouse samples (fig 5a). Sci Rep (2017) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; loading ...; fig 3b
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 4060) was used in western blot on mouse samples (fig 3b). Nature (2017) ncbi
rabbit monoclonal (D9E)
  • immunohistochemistry; mouse; loading ...; fig 7b
  • immunohistochemistry; human; loading ...; fig 5l
In order to demonstrate that WHSC1 drives indolent PTEN-null tumors to become metastatic prostate cancer, Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in immunohistochemistry on mouse samples (fig 7b) and in immunohistochemistry on human samples (fig 5l). J Clin Invest (2017) ncbi
rabbit monoclonal (D9E)
  • immunohistochemistry - paraffin section; mouse; 1:50; fig s7f
  • western blot; human; loading ...; fig 2a, 3b, 3c, 4a
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in immunohistochemistry - paraffin section on mouse samples at 1:50 (fig s7f) and in western blot on human samples (fig 2a, 3b, 3c, 4a). Mol Cell (2017) ncbi
rabbit monoclonal (D9E)
  • western blot; human; loading ...; fig 1b
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on human samples (fig 1b). Sci Rep (2017) ncbi
rabbit monoclonal (D9E)
  • immunohistochemistry - paraffin section; mouse; 1:50; loading ...; fig 4c
  • western blot; mouse; loading ...; fig 4b
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in immunohistochemistry - paraffin section on mouse samples at 1:50 (fig 4c) and in western blot on mouse samples (fig 4b). PLoS ONE (2017) ncbi
rabbit monoclonal (D9E)
  • western blot; human; loading ...; fig 1b
In order to observe that chronic presence of internalized Escherichia coli leads to enhanced oncogenicity in colon cancer cells, Cell Signaling Technology AKT1 antibody (cell signalling, 4060) was used in western blot on human samples (fig 1b). Cell Death Dis (2017) ncbi
rabbit monoclonal (D9E)
  • western blot; human; loading ...; fig 4c
  • western blot; mouse; fig 3b
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on human samples (fig 4c) and in western blot on mouse samples (fig 3b). Sci Signal (2017) ncbi
rabbit polyclonal
  • reverse phase protein lysate microarray; human; loading ...; fig st6
In order to characterize the molecular identity of uterine carcinosarcomas., Cell Signaling Technology AKT1 antibody (CST, 9271) was used in reverse phase protein lysate microarray on human samples (fig st6). Cancer Cell (2017) ncbi
rabbit monoclonal (D9E)
  • western blot; human; loading ...; fig 5d
In order to investigate origin of tumor-infiltrating T regulatory cells in breast cancer samples, Cell Signaling Technology AKT1 antibody (cell signalling, 4060) was used in western blot on human samples (fig 5d). Cell Res (2017) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; fig 1d
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on mouse samples (fig 1d). J Biol Chem (2017) ncbi
rabbit polyclonal
  • western blot; mouse; 1:1000; fig 13b
In order to explore the roles of activated portal fibroblasts and myofibroblasts in the pathogenesis of liver fibrosis induced by bile duct ligation, Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on mouse samples at 1:1000 (fig 13b). J Clin Invest (2017) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; loading ...; fig s6
In order to investigate the effects of boron treatment on adipogenesis, Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on mouse samples (fig s6). Metabolism (2017) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; fig 7a
In order to describe the effect of metformin on endoplasmic reticulum stress and autophagy in glucose-starved micro-vascular endothelial cells, Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on mouse samples (fig 7a). Biochem Pharmacol (2017) ncbi
rabbit monoclonal (D9E)
  • western blot; human; loading ...; fig 4a
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on human samples (fig 4a). PLoS ONE (2017) ncbi
rabbit monoclonal (D9E)
  • immunocytochemistry; human; loading ...; fig s1
In order to use machine-learning modeling with high-throughput cellular imaging to predict cellular sensitivity to tumor necrosis factor alpha, Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in immunocytochemistry on human samples (fig s1). Sci Rep (2017) ncbi
rabbit polyclonal
  • western blot; mouse; loading ...; fig EV4a
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on mouse samples (fig EV4a). EMBO Mol Med (2017) ncbi
rabbit monoclonal (D9E)
  • western blot; human; loading ...; fig 4a
Cell Signaling Technology AKT1 antibody (Cell Signaling, D9E) was used in western blot on human samples (fig 4a). PLoS ONE (2017) ncbi
rabbit polyclonal
  • western blot; human; 1:500; loading ...; fig 2a
In order to find focal adhesion pathways essential for cancer spheroids, Cell Signaling Technology AKT1 antibody (Cell signaling, 9271) was used in western blot on human samples at 1:500 (fig 2a). Int J Oncol (2017) ncbi
rabbit monoclonal (D9E)
  • western blot; human; loading ...; fig 1f
Cell Signaling Technology AKT1 antibody (Cell signalling, 4060) was used in western blot on human samples (fig 1f). Cancer Lett (2017) ncbi
rabbit monoclonal (D9E)
  • western blot; human; 1:2000; loading ...; fig 3c
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on human samples at 1:2000 (fig 3c). Biosci Rep (2017) ncbi
rabbit polyclonal
  • western blot; human; fig 4a
  • western blot; mouse; loading ...; fig 3a
In order to investigate the role of adiponectin in a mouse model of colitis, Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on human samples (fig 4a) and in western blot on mouse samples (fig 3a). J Biol Chem (2017) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; 1:1000; loading ...; fig 6e
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on mouse samples at 1:1000 (fig 6e). Theranostics (2017) ncbi
rabbit polyclonal
  • western blot; human; loading ...; fig 3a
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on human samples (fig 3a). Sci Rep (2017) ncbi
rabbit monoclonal (D9E)
  • western blot; human; loading ...; fig 6a
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on human samples (fig 6a). Mol Cancer Res (2017) ncbi
rabbit monoclonal (D9E)
  • flow cytometry; mouse; loading ...; fig 5e
  • western blot; mouse; 1:2000; loading ...; fig 3f
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in flow cytometry on mouse samples (fig 5e) and in western blot on mouse samples at 1:2000 (fig 3f). J Immunol (2017) ncbi
rabbit polyclonal
  • western blot; mouse; 1:1000; fig 6
Cell Signaling Technology AKT1 antibody (Cell Signalling, 9271) was used in western blot on mouse samples at 1:1000 (fig 6). PLoS ONE (2017) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; loading ...; fig 4a
In order to test if the TRPM4 channel contributes to physiological cardiac hypertrophy, Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on mouse samples (fig 4a). J Muscle Res Cell Motil (2017) ncbi
rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig 2b
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on human samples at 1:1000 (fig 2b). Nat Commun (2017) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; loading ...; fig 7a
Cell Signaling Technology AKT1 antibody (cell signalling, 4060) was used in western blot on mouse samples (fig 7a). Sci Rep (2017) ncbi
rabbit monoclonal (D9E)
  • western blot; rat; 1:2000; fig 4A
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on rat samples at 1:2000 (fig 4A). Int J Mol Med (2017) ncbi
rabbit monoclonal (D9E)
  • western blot; human; loading ...; fig 1a
  • western blot; mouse; loading ...; fig s9e
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on human samples (fig 1a) and in western blot on mouse samples (fig s9e). Nature (2017) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; loading ...; fig s9a
In order to report that phosphatidylinositol 3-kinase delta blockade promotes genomic instability in B cells, Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 4060) was used in western blot on mouse samples (fig s9a). Nature (2017) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; 1:2000; loading ...; fig 6g
Cell Signaling Technology AKT1 antibody (Cell Signaling Technologies, 4060) was used in western blot on mouse samples at 1:2000 (fig 6g). FASEB J (2017) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; loading ...; fig 3a
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on mouse samples (fig 3a). PLoS Pathog (2017) ncbi
rabbit polyclonal
  • western blot; human; 1:500; fig 1h
In order to demonstrate that IGF2 secreted by inhibitor of differentiation-overexpressing oesophageal cancer cells instigates VEGFR1-positive bone marrow cells in the tumor macroenvironment, Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 9271) was used in western blot on human samples at 1:500 (fig 1h). Nat Commun (2017) ncbi
rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig 3a
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on human samples at 1:1000 (fig 3a). FASEB J (2017) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; loading ...; fig 6e
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 4060) was used in western blot on mouse samples (fig 6e). J Cell Biol (2017) ncbi
rabbit monoclonal (D9E)
  • western blot; human; 1:1000; loading ...; fig 6a
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 4060) was used in western blot on human samples at 1:1000 (fig 6a). Oncotarget (2017) ncbi
rabbit polyclonal
  • western blot; rat; 1:1000; loading ...; fig 7a
In order to study the effects of periadventitial delivery of resveratrol on three major pro-restenotic pathologies, Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271 s) was used in western blot on rat samples at 1:1000 (fig 7a). Sci Rep (2017) ncbi
rabbit monoclonal (D9E)
  • immunohistochemistry; rat; 1:40; loading ...; fig 7c
In order to study the effects of periadventitial delivery of resveratrol on three major pro-restenotic pathologies, Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in immunohistochemistry on rat samples at 1:40 (fig 7c). Sci Rep (2017) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; loading ...; fig 12A
In order to implicate 25-hydroxycholesterol as an inducer of muscle wasting, Cell Signaling Technology AKT1 antibody (Cell signaling, 4060) was used in western blot on mouse samples (fig 12A). EBioMedicine (2017) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; 1:1000; loading ...; fig 7c
Cell Signaling Technology AKT1 antibody (cell signalling, 4060) was used in western blot on mouse samples at 1:1000 (fig 7c). Proc Natl Acad Sci U S A (2017) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; 1:2000; fig 9e
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 4060) was used in western blot on mouse samples at 1:2000 (fig 9e). J Cell Biol (2017) ncbi
rabbit monoclonal (D9E)
  • western blot; human; loading ...; fig 4a
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on human samples (fig 4a). Sci Rep (2017) ncbi
rabbit polyclonal
  • western blot; human; loading ...; fig s7a
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on human samples (fig s7a). Sci Rep (2017) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; loading ...; fig 1b
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 4060) was used in western blot on mouse samples (fig 1b). FEBS Lett (2017) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; loading ...; fig 4a
In order to research the role of vacuolar-type H+-ATPase complex in liver in the accumulation of autophagic vacuoles and lysosomes, Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on mouse samples (fig 4a). Autophagy (2017) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; loading ...; fig 5a
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on mouse samples (fig 5a). Autophagy (2017) ncbi
rabbit polyclonal
  • western blot; mouse; 1:500; loading ...; fig 1b
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on mouse samples at 1:500 (fig 1b). Mol Metab (2017) ncbi
rabbit monoclonal (D9E)
  • western blot; human; 1:1000; loading ...; fig 5a
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on human samples at 1:1000 (fig 5a). Oncol Lett (2017) ncbi
rabbit monoclonal (D9E)
  • western blot; rat; 1:1000; loading ...; fig 2a
Cell Signaling Technology AKT1 antibody (Cell signaling, 4060) was used in western blot on rat samples at 1:1000 (fig 2a). Exp Ther Med (2017) ncbi
rabbit monoclonal (D9E)
  • western blot; human; 1:1000; loading ...; fig 3d
In order to elucidate that mTORC1 presents tumor suppressor features in conditions of nutrient restrictions, Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on human samples at 1:1000 (fig 3d). Nat Commun (2017) ncbi
rabbit polyclonal
  • immunohistochemistry; pig; 1:100; loading ...; fig 6a
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in immunohistochemistry on pig samples at 1:100 (fig 6a). PLoS ONE (2017) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; loading ...; fig 5d, 5e,5f
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 4060) was used in western blot on mouse samples (fig 5d, 5e,5f). Sci Rep (2017) ncbi
rabbit polyclonal
  • western blot; mouse; 1:1000; loading ...; fig 4c
In order to investigate estrogen receptor alpha positive breast cancer, Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on mouse samples at 1:1000 (fig 4c). Breast Cancer Res (2017) ncbi
rabbit monoclonal (D9E)
  • flow cytometry; human; 1:200; loading ...; fig 3
In order to evaluate the methodology of microsphere cytometry for studying cellular microenvironment, Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in flow cytometry on human samples at 1:200 (fig 3). Integr Biol (Camb) (2017) ncbi
rabbit monoclonal (D9E)
  • immunocytochemistry; human; 1:500; loading ...; fig 4
  • western blot; human; 1:2000; loading ...; fig 5a
In order to report that cool-associated tyrosine phosphorylated protein-1 is required for anchorage-independent growth of cervical carcinoma cells, Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in immunocytochemistry on human samples at 1:500 (fig 4) and in western blot on human samples at 1:2000 (fig 5a). J Biol Chem (2017) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; loading ...; fig 3a
Cell Signaling Technology AKT1 antibody (Cell signaling, 4060) was used in western blot on mouse samples (fig 3a). Mol Biol Cell (2017) ncbi
rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig 1e
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on human samples at 1:1000 (fig 1e). Am J Physiol Cell Physiol (2017) ncbi
rabbit monoclonal (D9E)
  • western blot; human; loading ...; fig 3c,3d
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 4060) was used in western blot on human samples (fig 3c,3d). FEBS Open Bio (2017) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; loading ...; fig 2c
In order to describe how epithelial polarity proteins suppress malignant outgrowth, Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on mouse samples (fig 2c). J Exp Med (2017) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; 1:2000; fig s7a
In order to report the expression pattern of Gpr182 during development and adulthood using knockin mice, Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on mouse samples at 1:2000 (fig s7a). J Clin Invest (2017) ncbi
rabbit monoclonal (D9E)
  • western blot; human; 1:1000; loading ...; fig 2b
  • western blot; mouse; 1:1000; loading ...; fig 2b
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on human samples at 1:1000 (fig 2b) and in western blot on mouse samples at 1:1000 (fig 2b). Nat Commun (2017) ncbi
rabbit monoclonal (D9E)
  • immunocytochemistry; mouse; 1:500; fig 5a
  • western blot; mouse; 1:3000; loading ...; fig 7e
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in immunocytochemistry on mouse samples at 1:500 (fig 5a) and in western blot on mouse samples at 1:3000 (fig 7e). Nat Commun (2017) ncbi
rabbit monoclonal (D9E)
  • western blot; human; 1:100; loading ...; fig 3b
In order to show that quercetin inhibits the PI3K/AKT/mTOR and STAT3 pathways in primary effusion lymphoma, Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on human samples at 1:100 (fig 3b). J Nutr Biochem (2017) ncbi
rabbit monoclonal (D9E)
  • western blot; human; 1:2000; loading ...; fig 7c
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on human samples at 1:2000 (fig 7c). Oncogene (2017) ncbi
rabbit polyclonal
  • western blot; mouse; 1:5000; loading ...; fig 5d
In order to determine a physiological role for IL-1beta and insulin in the regulation of both metabolism and immunity, Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on mouse samples at 1:5000 (fig 5d). Nat Immunol (2017) ncbi
rabbit polyclonal
  • western blot; human; 1:1000; loading ...
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on human samples at 1:1000. J Neuroinflammation (2017) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; 1:1000; loading ...; fig 9d
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on mouse samples at 1:1000 (fig 9d). J Neurosci (2017) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; fig 5c
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on mouse samples (fig 5c). Stem Cell Reports (2017) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; 1:2000; fig 5a
Cell Signaling Technology AKT1 antibody (Cell signaling, 4060) was used in western blot on mouse samples at 1:2000 (fig 5a). PLoS ONE (2017) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; loading ...; fig s4a
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060s) was used in western blot on mouse samples (fig s4a). PLoS Genet (2017) ncbi
rabbit monoclonal (D9E)
  • western blot; human; 1:1000; loading ...; fig 1b
In order to demonstrate a crosstalk between stromal fibroblasts and epithelial cells under starvation, Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on human samples at 1:1000 (fig 1b). Nat Commun (2017) ncbi
rabbit polyclonal
  • western blot; mouse; loading ...; fig 1b
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on mouse samples (fig 1b). J Biol Chem (2017) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; loading ...; fig 6b
In order to confirm that FBXL5 contributes to regulation of neural stem-progenitor cells proliferation during mammalian brain development, Cell Signaling Technology AKT1 antibody (CST, 4060) was used in western blot on mouse samples (fig 6b). Mol Cell Biol (2017) ncbi
rabbit monoclonal (D9E)
  • western blot; human; loading ...; fig 4a
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on human samples (fig 4a). Cardiovasc Res (2017) ncbi
rabbit polyclonal
  • western blot; human; loading ...; fig 4d
In order to show the Nogo-B receptor promotes accumulation of prenylated Ras at the plasma membrane, Cell Signaling Technology AKT1 antibody (cell signalling, 9271) was used in western blot on human samples (fig 4d). Oncogene (2017) ncbi
rabbit polyclonal
  • western blot; mouse; 1:1000; loading ...; fig 5h
In order to determine that metalloproteinase ADAMTS1 and inducible nitric oxide synthase are potential therapeutic targets in individuals with thoracic aortic aneurysms and dissections, Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on mouse samples at 1:1000 (fig 5h). Nat Med (2017) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; 1:1000; loading ...; fig 3c
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, D9E) was used in western blot on mouse samples at 1:1000 (fig 3c). J Clin Invest (2017) ncbi
rabbit monoclonal (D9E)
  • western blot; human; 1:1000; loading ...; fig 3a
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on human samples at 1:1000 (fig 3a). J Biol Chem (2017) ncbi
rabbit monoclonal (D9E)
  • western blot; rat; 1:2000; loading ...; fig 7a
In order to assess the possible mechanism underlying the protective effect of tetramethylpyrazine against disuse-induced muscle atrophy, Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060S) was used in western blot on rat samples at 1:2000 (fig 7a). Appl Physiol Nutr Metab (2017) ncbi
rabbit monoclonal (D9E)
  • western blot; human; fig s2b
In order to determine the role of p21-activated kinases in response to BRAF inhibitors, Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on human samples (fig s2b). Mol Carcinog (2017) ncbi
rabbit monoclonal (D9E)
  • western blot; human; loading ...; fig s2d
In order to define and study the androgen response element within the SEMA3C locus, Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060S) was used in western blot on human samples (fig s2d). Oncotarget (2017) ncbi
rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig 3a
In order to develop a novel foreskin model to examine developmental programming in human neonates, Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271S) was used in western blot on human samples at 1:1000 (fig 3a). Exp Gerontol (2017) ncbi
rabbit monoclonal (D9E)
  • western blot; common platanna; loading ...; fig 4a
In order to find that the Glu/Asp transporter SLC1A3 is localized to the plasma membrane and the major regulator of acidic amino acid uptake in adipocytes, Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on common platanna samples (fig 4a). FEBS Lett (2017) ncbi
rabbit polyclonal
  • western blot; human; 1:1000; loading ...; tbl 3
In order to report the presence of PIWI-like proteins in somatic cells and the possible role of HIWI2 in preserving the functional integrity of epithelial cells, Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on human samples at 1:1000 (tbl 3). Mol Cell Biochem (2017) ncbi
rabbit polyclonal
  • western blot; rat; 1:500; fig 1b
In order to assess the role of Pyk2 in phenotype modulation in rat carotid artery smooth muscle cells and in cultured intact arteries, Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on rat samples at 1:500 (fig 1b). J Cell Physiol (2017) ncbi
rabbit polyclonal
  • western blot; mouse; loading ...; fig 6e
In order to analyze 2 members of a novel class of NF-kB inhibitors in both mouse and golden retriever muscular dystrophy dog models of Duchenne muscular dystrophy, Cell Signaling Technology AKT1 antibody (Cell Signalling, 9271) was used in western blot on mouse samples (fig 6e). JCI Insight (2016) ncbi
rabbit polyclonal
  • western blot; human; loading ...
In order to analyze the context specificity of signaling networks within a causal conceptual framework using reverse-phase protein array time-course assays and network analysis approaches, Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 9271) was used in western blot on human samples . Cell Syst (2017) ncbi
rabbit monoclonal (D9E)
  • western blot; rat; loading ...; fig 2f
  • western blot; mouse; loading ...; fig 2e
Cell Signaling Technology AKT1 antibody (Cell Signalling, 4060) was used in western blot on rat samples (fig 2f) and in western blot on mouse samples (fig 2e). Hum Mol Genet (2017) ncbi
rabbit polyclonal
  • western blot; human; loading ...; fig 5
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on human samples (fig 5). Sci Rep (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; human; 1:1000; loading ...; fig 4a
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on human samples at 1:1000 (fig 4a). Oncotarget (2017) ncbi
rabbit monoclonal (D9E)
  • western blot; human; fig 1c
In order to assess the effects of LY3009120, a panRAF and RAF dimer inhibitor, in human models of colorectal cancer, Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on human samples (fig 1c). Oncotarget (2017) ncbi
rabbit polyclonal
  • western blot; human; loading ...; fig 5a
Cell Signaling Technology AKT1 antibody (cell signalling, 9271) was used in western blot on human samples (fig 5a). PLoS Med (2016) ncbi
rabbit polyclonal
  • western blot; human; 1:500; loading ...; fig 6a
In order to examine the role of Breast Cancer Associated gene 2 in EGFR endocytosis and down-regulation and to determine its links with breast cancer outcome, Cell Signaling Technology AKT1 antibody (Cell signaling, 9271) was used in western blot on human samples at 1:500 (fig 6a). J Cancer (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; human; 1:1000; loading ...; fig s6
In order to elucidate tumor-derived factors and genetic changes in endothelial cells that contribute to excess centrosomes in tumor endothelial cells, Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on human samples at 1:1000 (fig s6). PLoS ONE (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; loading ...
In order to find that that vascular endothelial growth factor 165b prevents activation of vascular endothelial growth factor receptor 1-STAT3 signaling by vascular endothelial growth factor 165a, Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on mouse samples . Circ Res (2017) ncbi
rabbit monoclonal (D9E)
  • western blot; human; 1:1000; loading ...; fig 6d
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on human samples at 1:1000 (fig 6d). Nat Commun (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; loading ...; fig 2b
In order to explore the role of transient receptor potential cation channel 6 in podocyte damage, Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on mouse samples (fig 2b). Cell Physiol Biochem (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; human; loading ...; fig 3a
Cell Signaling Technology AKT1 antibody (Cell Signaling, D9E) was used in western blot on human samples (fig 3a). J Immunol (2017) ncbi
rabbit monoclonal (D9E)
  • immunohistochemistry - paraffin section; mouse; loading ...; fig 3f
  • immunocytochemistry; mouse; 1:200; loading ...; fig s7c
  • western blot; mouse; 1:1000; loading ...; fig s5a
In order to discuss how NLRC3 protects against colorectal cancer by modulating mTor signaling, Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in immunohistochemistry - paraffin section on mouse samples (fig 3f), in immunocytochemistry on mouse samples at 1:200 (fig s7c) and in western blot on mouse samples at 1:1000 (fig s5a). Nature (2016) ncbi
rabbit polyclonal
  • western blot; mouse; loading ...; fig 4
In order to study mouse models of dilated cardiomyopathy to study calcium signaling, Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on mouse samples (fig 4). PLoS ONE (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; loading ...; fig 3
In order to propose that casitas B-cell lymphoma family proteins protect mammary epithelial cells from proteotoxic stress-induced cell death by promoting turnover of active c-Src, Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on mouse samples (fig 3). Proc Natl Acad Sci U S A (2016) ncbi
rabbit polyclonal
  • immunocytochemistry; human; loading ...; fig 6b
  • western blot; human; loading ...; fig 6a
Cell Signaling Technology AKT1 antibody (Cell signaling, 9271) was used in immunocytochemistry on human samples (fig 6b) and in western blot on human samples (fig 6a). J Exp Clin Cancer Res (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; loading ...; fig s3b
In order to identify gephyrin as a druggable target for pancreatic beta cell regeneration, Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060P) was used in western blot on mouse samples (fig s3b). Cell (2017) ncbi
rabbit polyclonal
  • western blot; human; 1:500; loading ...; fig 1f
In order to discuss mutations that contribute to atopic dermatitis, Cell Signaling Technology AKT1 antibody (Cell signaling, 9271) was used in western blot on human samples at 1:500 (fig 1f). J Allergy Clin Immunol (2017) ncbi
rabbit monoclonal (D9E)
  • immunohistochemistry; mouse; loading ...; fig 3d
In order to use transgenic mice to assess the effects of progressively disrupting Hras and Nras genes on urethane lung tumorigenesis, Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in immunohistochemistry on mouse samples (fig 3d). PLoS ONE (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; rat; 1:1000; loading ...; fig 2c
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on rat samples at 1:1000 (fig 2c). Mol Med Rep (2017) ncbi
rabbit monoclonal (D9E)
  • western blot; human; loading ...; fig s5a
In order to evaluate several GSK3 antibodies, Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on human samples (fig s5a). Front Mol Neurosci (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; human; loading ...; fig 2b
Cell Signaling Technology AKT1 antibody (Cell signaling, 4060) was used in western blot on human samples (fig 2b). J Biol Chem (2017) ncbi
rabbit polyclonal
  • western blot; mouse; loading ...; fig 2
Cell Signaling Technology AKT1 antibody (cell signalling, 9271) was used in western blot on mouse samples (fig 2). Nature (2016) ncbi
rabbit polyclonal
  • western blot; human; loading ...; fig 2a
In order to show that 2-hydroxyoleic acid treatment alters cell signaling and intracellular transport, Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on human samples (fig 2a). Oncotarget (2016) ncbi
rabbit polyclonal
  • western blot; human; 1:3000; loading ...; fig 6a
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 9271-S) was used in western blot on human samples at 1:3000 (fig 6a). Oncogene (2017) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; loading ...; fig 4d
In order to engineer and characterize a second-generation, high-affinity AXL decoy receptor, Cell Signaling Technology AKT1 antibody (CST, 4060) was used in western blot on mouse samples (fig 4d). J Clin Invest (2017) ncbi
rabbit polyclonal
  • western blot; mouse; 1:1000; fig 5d-f
In order to test if Fsp27 silencing improves obesity, fatty liver, and glycemic control, Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on mouse samples at 1:1000 (fig 5d-f). J Lipid Res (2017) ncbi
rabbit polyclonal
  • western blot; mouse; loading ...; fig 4i
In order to show that DNA hypermethylation at the PPARgamma1 promoter is induced by obesity-related factors, Cell Signaling Technology AKT1 antibody (Cell signaling, 9271) was used in western blot on mouse samples (fig 4i). JCI Insight (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; rat; loading ...; fig 6d
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060L) was used in western blot on rat samples (fig 6d). J Neurosci (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; human; loading ...; fig 7
In order to report the effects of NVP-CGM097 on the p53wildtype GOT1 cells, Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on human samples (fig 7). Neuroendocrinology (2018) ncbi
rabbit monoclonal (D9E)
  • western blot; human; 1:1000; loading ...; fig s4a,s4b
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on human samples at 1:1000 (fig s4a,s4b). Gastroenterology (2017) ncbi
rabbit monoclonal (D9E)
  • western blot; human; loading ...; fig 4a
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on human samples (fig 4a). Int J Nanomedicine (2016) ncbi
rabbit polyclonal
  • western blot; human; loading ...; fig 2a
In order to study the mechanisms driving uterine leiomyoma growth and survival via aberrant activation of AKT, Cell Signaling Technology AKT1 antibody (Cell signaling, 9271) was used in western blot on human samples (fig 2a). Sci Adv (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; 1:2000; fig 8h
In order to identify Ret as a downstream mediator of DUX4 signaling, Cell Signaling Technology AKT1 antibody (Cell Signalling, D9E) was used in western blot on mouse samples at 1:2000 (fig 8h). elife (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; loading ...; fig 7a
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on mouse samples (fig 7a). Int J Mol Med (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; human; fig 2a, 2b, 2c
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on human samples (fig 2a, 2b, 2c). Oncotarget (2016) ncbi
rabbit polyclonal
  • western blot; human; 1:1000; fig 4a
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on human samples at 1:1000 (fig 4a). Front Immunol (2016) ncbi
rabbit monoclonal (D9E)
  • immunohistochemistry - paraffin section; human; fig 6d
  • western blot; human; loading ...; fig 5a
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in immunohistochemistry - paraffin section on human samples (fig 6d) and in western blot on human samples (fig 5a). Sci Rep (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; rat; 1:1000; loading ...; fig 2
In order to measure brain insulin signaling in response to dexamethasone treatment in female Charles Foster rats, Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on rat samples at 1:1000 (fig 2). Mol Neurobiol (2017) ncbi
rabbit monoclonal (D9E)
  • western blot; hamsters; fig 1b
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on hamsters samples (fig 1b). Nature (2016) ncbi
rabbit polyclonal
  • western blot; human; loading ...; fig 2c
Cell Signaling Technology AKT1 antibody (CST, 9271S) was used in western blot on human samples (fig 2c). Nat Chem Biol (2017) ncbi
rabbit monoclonal (D9E)
  • western blot; human; loading ...; fig 6a
In order to generate and characterize an antibody that is specific for the insulin receptor and evaluate its effect on diabetic pathogenesis, Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on human samples (fig 6a). Diabetes (2017) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; loading ...; fig 1c
In order to determine if PIK3CA mutations contribute to tumor initiation, Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on mouse samples (fig 1c). Oncogenesis (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; human; loading ...; fig 1b
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on human samples (fig 1b). J Clin Invest (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; human; loading ...; fig 4a
In order to identify autophagy-inducing phytochemicals, Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 4060) was used in western blot on human samples (fig 4a). Autophagy (2017) ncbi
rabbit polyclonal
  • western blot; human; loading ...; fig 3b
In order to identify a role for STAM1 in CXCR4-dependent chemotaxis, Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on human samples (fig 3b). J Biol Chem (2016) ncbi
rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig 3a
In order to discover that mTOR is a calmodulin-dependent kinase, Cell Signaling Technology AKT1 antibody (Cell signaling, 9271) was used in western blot on human samples at 1:1000 (fig 3a). elife (2016) ncbi
rabbit monoclonal (D9E)
  • immunohistochemistry - paraffin section; human; loading ...; fig 6d
  • western blot; human; 1:1000; loading ...; fig 3b
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 4060) was used in immunohistochemistry - paraffin section on human samples (fig 6d) and in western blot on human samples at 1:1000 (fig 3b). Cell Signal (2017) ncbi
rabbit monoclonal (D9E)
  • immunocytochemistry; mouse; 1:1000; loading ...; fig 1c
In order to identify factors that trigger central nervous system myelination, Cell Signaling Technology AKT1 antibody (Cell signaling, 4060) was used in immunocytochemistry on mouse samples at 1:1000 (fig 1c). Nat Neurosci (2017) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; loading ...; fig 5a
In order to study the role of miR-7 in acute lung injury, Cell Signaling Technology AKT1 antibody (CST, 4060) was used in western blot on mouse samples (fig 5a). Front Immunol (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; loading ...; fig 2g
In order to test both peripheral and central effects of exercise training combined with a cholesterol-rich diet in old ApoE knockout mice, Cell Signaling Technology AKT1 antibody (Cell signaling, 4060) was used in western blot on mouse samples (fig 2g). Front Physiol (2016) ncbi
rabbit polyclonal
  • western blot; mouse; 1:1000; loading ...; fig s4b
Cell Signaling Technology AKT1 antibody (Cell signaling, 9271) was used in western blot on mouse samples at 1:1000 (fig s4b). Neoplasia (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; human; fig 5a
In order to determine the effects of high glucose on the epithelial-mesenchymal transition in retinal pigment epithelial cells, Cell Signaling Technology AKT1 antibody (Cell signaling, 4060S) was used in western blot on human samples (fig 5a). Int J Mol Med (2016) ncbi
rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig 7
In order to examine the antitumor autoantibody responses in African American and European American men with prostate cancer, Cell Signaling Technology AKT1 antibody (Cell signaling, 9271) was used in western blot on human samples at 1:1000 (fig 7). Mol Cell Proteomics (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; fig 2
In order to identify and characterize a biliverdin reductase A-glycogen synthase kinase 3beta-peroxisome proliferator-activated receptor alpha axis that regulates hepatic lipid metabolism, Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060S) was used in western blot on mouse samples (fig 2). J Biol Chem (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; 1:2000; loading ...; fig 3d
In order to describe how amino acids and Lamtor1 regulate macrophage polarization, Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on mouse samples at 1:2000 (fig 3d). Nat Commun (2016) ncbi
rabbit polyclonal
  • immunohistochemistry - paraffin section; human
Cell Signaling Technology AKT1 antibody (Cell Signalling, 9271) was used in immunohistochemistry - paraffin section on human samples . Respir Res (2016) ncbi
rabbit polyclonal
  • western blot; mouse; 1:5000; loading ...; fig 4e
Cell Signaling Technology AKT1 antibody (Cell signalling, 9271) was used in western blot on mouse samples at 1:5000 (fig 4e). Nat Commun (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; rat; loading ...; fig 4c
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on rat samples (fig 4c). J Neurosci (2016) ncbi
rabbit polyclonal
  • western blot; human; loading ...; fig 9c
In order to study chaperome complexes in a large set of tumor specimens, Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on human samples (fig 9c). Nature (2016) ncbi
rabbit polyclonal
  • western blot; human; loading ...; fig 3b
In order to demonstrate that entinostat targets SALL4-positive lung cancer, Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on human samples (fig 3b). Oncotarget (2016) ncbi
rabbit polyclonal
  • immunocytochemistry; mouse
  • western blot; mouse; fig 1
  • western blot; human; fig 7
In order to elucidate the compartmentalization of p110alpha and p110beta, Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in immunocytochemistry on mouse samples , in western blot on mouse samples (fig 1) and in western blot on human samples (fig 7). elife (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; human; loading ...; fig 5a
Cell Signaling Technology AKT1 antibody (Cell Signaling, D9E) was used in western blot on human samples (fig 5a). Cancer Sci (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; loading ...; fig 3b
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on mouse samples (fig 3b). Nat Immunol (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; 1:1000; loading ...; fig 5b
In order to demonstrate that missense mutations in NEDD4L result in periventricular nodular heterotopia associated with toe syndactyly, cleft palate, and neurodevelopmental delay, Cell Signaling Technology AKT1 antibody (Cell Signalling, 4060) was used in western blot on mouse samples at 1:1000 (fig 5b). Nat Genet (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; human; 1:1000; loading ...; fig s1b
In order to elucidate the role of DUOX1 silencing in lung cancer development or progression, Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060X) was used in western blot on human samples at 1:1000 (fig s1b). Oncogenesis (2016) ncbi
rabbit polyclonal
  • western blot; human; loading ...; fig 6b
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on human samples (fig 6b). J Cell Mol Med (2017) ncbi
rabbit monoclonal (D9E)
  • western blot; human; 1:1000; loading ...; fig 4a
In order to elucidate the upstream mechanisms of apoptosis triggered by an anti-microtubule drug, ABT-751, Cell Signaling Technology AKT1 antibody (cell signalling, 4060) was used in western blot on human samples at 1:1000 (fig 4a). Toxicol Appl Pharmacol (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; human; fig 3
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on human samples (fig 3). Cell Discov (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; human; fig 4
In order to report that short-chain fatty acids act via FFAR2/3 to alter human monocyte inflammatory responses, Cell Signaling Technology AKT1 antibody (Cell Signalling, 4060) was used in western blot on human samples (fig 4). Sci Rep (2016) ncbi
rabbit monoclonal (D9E)
  • immunohistochemistry - paraffin section; human; 1:200; loading ...; fig s23
  • western blot; human; 1:1000; loading ...; fig 2b
In order to delineate the mechanism for lung tumorigenesis by a tobacco-specific carcinogen, Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in immunohistochemistry - paraffin section on human samples at 1:200 (fig s23) and in western blot on human samples at 1:1000 (fig 2b). Nat Commun (2016) ncbi
rabbit polyclonal
  • western blot; mouse; loading ...; fig 3a
In order to assess cyclic alterations of lipid metabolism over a 24-hour period after binge in small heterodimer partner nuclear receptor knockout mice, Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on mouse samples (fig 3a). Am J Pathol (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; human; 1:1000; loading ...; fig 4f
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on human samples at 1:1000 (fig 4f). Oncotarget (2016) ncbi
rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig 3c
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on human samples at 1:1000 (fig 3c). Oncotarget (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; human; 1:1000; fig 3
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on human samples at 1:1000 (fig 3). Cell Commun Signal (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; human; 1:1000; loading ...; fig 1d
Cell Signaling Technology AKT1 antibody (cell signalling, 4060) was used in western blot on human samples at 1:1000 (fig 1d). Oncotarget (2016) ncbi
rabbit polyclonal
  • western blot; human; 1:1000; tbl 1
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on human samples at 1:1000 (tbl 1). J Neuroinflammation (2016) ncbi
rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig s7c
In order to propose that leukemia inhibitory factor signaling confers a dormancy phenotype in breast cancer cells that have disseminated to bone, Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on human samples at 1:1000 (fig s7c). Nat Cell Biol (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; human; 1:1000; loading ...; fig 5e
In order to test if OSU-T315 inhibits vestibular schwannoma and meningioma cell growth, Cell Signaling Technology AKT1 antibody (Cell Signaling, D9E) was used in western blot on human samples at 1:1000 (fig 5e). Austin J Med Oncol (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; Chinese hamster; fig 2
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on Chinese hamster samples (fig 2). Sci Rep (2016) ncbi
rabbit polyclonal
  • western blot; human; fig 2
In order to describe the effects of long- and short-term exposure to erythropoietin on white adipose tissue, Cell Signaling Technology AKT1 antibody (Cell signaling, 9271) was used in western blot on human samples (fig 2). Lipids Health Dis (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; human; fig 6i
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on human samples (fig 6i). Oncotarget (2016) ncbi
rabbit polyclonal
  • western blot; human; loading ...; fig 6c
In order to analyze pro- and anti-lipolytic signaling pathways in adipocytes after in vivo endotoxin exposure, Cell Signaling Technology AKT1 antibody (Cell signaling, 9271) was used in western blot on human samples (fig 6c). PLoS ONE (2016) ncbi
rabbit polyclonal
  • western blot; human; 1:1000; fig 1
In order to elucidate the mechanisms by which mutant IDH1/2 contributes to oncogenesis, Cell Signaling Technology AKT1 antibody (Cell signaling, 9271) was used in western blot on human samples at 1:1000 (fig 1). Nat Commun (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; zebrafish ; 1:2000; loading ...; fig 1f
In order to show that Flt4 regulates lymphatic morphogenesis and differentiation in different portions of zebrafish, Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on zebrafish samples at 1:2000 (fig 1f). Development (2016) ncbi
rabbit monoclonal (D9E)
  • flow cytometry; mouse; loading ...; fig 7c
In order to demonstrate that Siglec-E is required for Escherichia coli-induced endocytosis of TLR4, Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in flow cytometry on mouse samples (fig 7c). J Immunol (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; human; loading ...; fig 4d
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on human samples (fig 4d). Oncotarget (2016) ncbi
rabbit polyclonal
  • immunohistochemistry - frozen section; rat; 1:25; fig 3
In order to elucidate the mechanism by which Brn3b protects retinal ganglion cells, Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in immunohistochemistry - frozen section on rat samples at 1:25 (fig 3). Mol Vis (2016) ncbi
rabbit polyclonal
  • western blot; human; loading ...; fig 4b
In order to compare dabrafenib-resistant and -sensitive BRAF-mutant human melanoma cell lines, Cell Signaling Technology AKT1 antibody (Cell signaling, 9271) was used in western blot on human samples (fig 4b). Int J Oncol (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; human; 1:2000; fig s5b
In order to study the role of the RAS/MAPK pathway in hypertrophic cardiomyopathy, Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 4060) was used in western blot on human samples at 1:2000 (fig s5b). Stem Cell Reports (2016) ncbi
rabbit polyclonal
  • western blot; mouse; loading ...; fig 7a
In order to explore the role of GRK2 in skeletal muscle physiology, Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271L) was used in western blot on mouse samples (fig 7a). J Biol Chem (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; human; fig s2
Cell Signaling Technology AKT1 antibody (Cell signaling, 4060) was used in western blot on human samples (fig s2). Nucleic Acids Res (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; human; 1:1000; fig 2a
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 4060) was used in western blot on human samples at 1:1000 (fig 2a). BMC Cancer (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; human; loading ...; fig 1a
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on human samples (fig 1a). J Biol Chem (2016) ncbi
rabbit polyclonal
  • western blot; human; loading ...; fig 6a
In order to report that inhibition of PP2A kills PLK1-overexpressing breast, pancreatic, ovarian, glioblastoma, and prostate cancer cells, Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on human samples (fig 6a). Oncotarget (2016) ncbi
rabbit polyclonal
  • western blot; mouse; 1:250; loading ...; fig s7e
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 9271S) was used in western blot on mouse samples at 1:250 (fig s7e). Nature (2016) ncbi
rabbit polyclonal
  • western blot; human; loading ...; fig 3a
Cell Signaling Technology AKT1 antibody (cell signalling, 9271) was used in western blot on human samples (fig 3a). Oncotarget (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; dog; loading ...; fig 6a
  • western blot; human; loading ...; fig 4a
In order to propose that loss of Llgl1 results in epidermal growth factor receptor mislocalization and leads to pre-neoplastic changes, Cell Signaling Technology AKT1 antibody (cell signalling, 4060) was used in western blot on dog samples (fig 6a) and in western blot on human samples (fig 4a). Oncotarget (2016) ncbi
rabbit polyclonal
  • western blot; mouse; loading ...; fig 9f
In order to explore how ST8SIA2-mediated polysialylation influences oligodendrocyte differentiation and schizophrenia, Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on mouse samples (fig 9f). Glia (2017) ncbi
rabbit polyclonal
  • western blot; human; 1:1500; loading ...; fig 4b
In order to study the impact of ephrin signaling in non-small cell lung cancer, Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on human samples at 1:1500 (fig 4b). Oncotarget (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; human; loading ...; fig 3, s3
Cell Signaling Technology AKT1 antibody (NEB (Hitchin, UK), 4060S) was used in western blot on human samples (fig 3, s3). Br J Cancer (2016) ncbi
rabbit polyclonal
  • western blot; mouse; loading ...; fig 5d
In order to show that pituitary tumor transforming gene 1 expression is upregulated in an mammalian/mechanistic target of rapamycin complex 1-dependent manner, Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on mouse samples (fig 5d). Oncogene (2017) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; loading ...; fig 7h
Cell Signaling Technology AKT1 antibody (Cell signaling, D9E) was used in western blot on mouse samples (fig 7h). Cell Mol Immunol (2017) ncbi
rabbit polyclonal
  • western blot; rat; loading ...; fig 4a
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271s) was used in western blot on rat samples (fig 4a). PLoS ONE (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; human; 1:1000; loading ...; fig 4.a, b, c
Cell Signaling Technology AKT1 antibody (CST, 4060) was used in western blot on human samples at 1:1000 (fig 4.a, b, c). EJNMMI Res (2016) ncbi
rabbit polyclonal
  • western blot; mouse; loading ...; fig 3a
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on mouse samples (fig 3a). Exp Mol Med (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; human; loading ...; fig 6a, 6d
In order to study the contribution of the heregulin-1/HER3-driven pathway to hepatocellular carcinoma, Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on human samples (fig 6a, 6d). J Exp Clin Cancer Res (2016) ncbi
rabbit polyclonal
  • western blot; mouse; loading ...; fig 3c
In order to measure the expression and function of neuromedin U receptor 2 and its ligands in gestational tissues, Cell Signaling Technology AKT1 antibody (Cell signaling, 9271) was used in western blot on mouse samples (fig 3c). Biol Reprod (2016) ncbi
rabbit polyclonal
  • western blot; rat; loading ...; fig 1
Cell Signaling Technology AKT1 antibody (cell Signaling, 9271) was used in western blot on rat samples (fig 1). Sci Rep (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; loading ...; fig 3f
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on mouse samples (fig 3f). Cell Rep (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; human; loading ...; fig 2a
Cell Signaling Technology AKT1 antibody (Cell Signaling, CST-4060) was used in western blot on human samples (fig 2a). Oncotarget (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; human; loading ...; fig 5A
Cell Signaling Technology AKT1 antibody (Cell signaling, D9E) was used in western blot on human samples (fig 5A). Oncotarget (2016) ncbi
rabbit monoclonal (D9E)
  • immunohistochemistry - paraffin section; mouse; 1:100; loading ...; fig 7e
  • immunocytochemistry; human; loading ...; fig 4c,4d
  • western blot; human; 1:1000; loading ...; fig 5,6
Cell Signaling Technology AKT1 antibody (CST, 4060) was used in immunohistochemistry - paraffin section on mouse samples at 1:100 (fig 7e), in immunocytochemistry on human samples (fig 4c,4d) and in western blot on human samples at 1:1000 (fig 5,6). Oncotarget (2016) ncbi
rabbit polyclonal
  • western blot; rat; fig 2
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on rat samples (fig 2). Physiol Rep (2016) ncbi
rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig 6b
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 9271) was used in western blot on human samples at 1:1000 (fig 6b). Cancer Chemother Pharmacol (2016) ncbi
rabbit monoclonal (D9E)
  • immunohistochemistry; mouse; 1:50; fig s2
In order to investigate the roles of NF2, LATS1/2, and YAP in the branching morphogenesis of the mouse kidney, Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in immunohistochemistry on mouse samples at 1:50 (fig s2). Nat Commun (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; human; fig 5c
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on human samples (fig 5c). Oncotarget (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; human; fig 7a
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 4060) was used in western blot on human samples (fig 7a). Oncotarget (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; human; fig 2
Cell Signaling Technology AKT1 antibody (Cell Signaling Tech, 4060S) was used in western blot on human samples (fig 2). Oncoimmunology (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; 1:2000; fig 6
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on mouse samples at 1:2000 (fig 6). PLoS ONE (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; human; 1:1000; fig 2
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on human samples at 1:1000 (fig 2). Oncol Lett (2016) ncbi
rabbit polyclonal
  • western blot; human; 1:1000; fig 3
Cell Signaling Technology AKT1 antibody (Cell Signaling Tech, 9271S) was used in western blot on human samples at 1:1000 (fig 3). Oncol Lett (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; human; fig 4e
Cell Signaling Technology AKT1 antibody (Cell Signaling, D9E) was used in western blot on human samples (fig 4e). Sci Rep (2016) ncbi
rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig 4c
In order to explore the role of insulin receptor substrate-1 in tumor development, Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on human samples at 1:1000 (fig 4c). Proc Natl Acad Sci U S A (2016) ncbi
rabbit monoclonal (D9E)
  • immunocytochemistry; human; loading ...; fig 4a
  • western blot; human; loading ...; fig 2a
In order to assess the importance of the IGF1R tyrosine kinase in triple-negative gastric cancer with and without oncogenic KRAS, BRAF or PI3K3CA mutations, Cell Signaling Technology AKT1 antibody (Cell signaling, 4060) was used in immunocytochemistry on human samples (fig 4a) and in western blot on human samples (fig 2a). Oncotarget (2016) ncbi
rabbit polyclonal
  • western blot; mouse; loading ...; fig 1d
In order to propose that PTEN's role in axonal polarity can be independent of PIP3, Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on mouse samples (fig 1d). Biochim Biophys Acta (2016) ncbi
rabbit polyclonal
  • western blot; rat; 1:1000; loading ...; fig 5c
In order to elucidate how miR-21-5p alleviates traumatic brain injury in rats, Cell Signaling Technology AKT1 antibody (CST, 9271S) was used in western blot on rat samples at 1:1000 (fig 5c). Brain Res (2016) ncbi
rabbit polyclonal
  • western blot; human; 1:1000; fig 6
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on human samples at 1:1000 (fig 6). Sci Rep (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; human; fig 6
Cell Signaling Technology AKT1 antibody (Cell Signaling, D9E) was used in western blot on human samples (fig 6). Sci Rep (2016) ncbi
rabbit polyclonal
  • western blot; mouse; 1:1000; fig 5
Cell Signaling Technology AKT1 antibody (Cell signaling, 9271) was used in western blot on mouse samples at 1:1000 (fig 5). Nat Commun (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; fig 4
In order to determine the reduction of proliferation in embryonic stem cells via FOXO3A/beta-catenin-dependent transcription of p21(cip1) caused by glucose-induced oxidative stress, Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 4060) was used in western blot on mouse samples (fig 4). Stem Cell Reports (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; human; fig 4b
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on human samples (fig 4b). Nucleic Acids Res (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; human; 1:2000; fig 5e
In order to discuss the role of myeloid cells in pancreatic cancer pathogenesis, Cell Signaling Technology AKT1 antibody (cell signalling, 4060) was used in western blot on human samples at 1:2000 (fig 5e). Gut (2017) ncbi
rabbit polyclonal
  • western blot; human; 1:1000; fig s2
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on human samples at 1:1000 (fig s2). Nat Commun (2016) ncbi
rabbit polyclonal
  • western blot; mouse; loading ...; fig 7d
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on mouse samples (fig 7d). J Clin Invest (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; human; loading ...; fig 4a
In order to identify signaling pathways that mediate the EGF-induced epithelial to mesenchymal transition, Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on human samples (fig 4a). J Proteomics (2017) ncbi
rabbit polyclonal
  • western blot; mouse; 1:1000; loading ...; fig 2i
In order to test if mammalian target of rapamycin complex 2 contributes to podocyte injury during diabetes, Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on mouse samples at 1:1000 (fig 2i). Antioxid Redox Signal (2016) ncbi
rabbit polyclonal
  • western blot; rat; fig 1c
In order to elucidate the anti-diabetic activity of ampelopsin, Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 9271) was used in western blot on rat samples (fig 1c). PLoS ONE (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; human; 1:2000; loading ...; fig 3
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 4060) was used in western blot on human samples at 1:2000 (fig 3). Oncotarget (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; human; loading ...; fig 2b
Cell Signaling Technology AKT1 antibody (Cell Signalling, 4060) was used in western blot on human samples (fig 2b). Oncotarget (2016) ncbi
rabbit polyclonal
  • western blot; human; fig 6
In order to characterize attenuation of endosomal EGFR signaling by cathepsin S as a mechanical rationale for the combination of EGFR tyrosine kinase and cathepsin S inhibitors, Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on human samples (fig 6). Sci Rep (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; human; loading ...; fig 6a
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 4060s) was used in western blot on human samples (fig 6a). Oncotarget (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; rat; 1:500; fig 3
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060 s) was used in western blot on rat samples at 1:500 (fig 3). Braz J Med Biol Res (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; 1:1000; fig 3c
In order to explore how the interaction between beta1-integrin and Fgf2 contributes to the satellite cell niche, Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on mouse samples at 1:1000 (fig 3c). Nat Med (2016) ncbi
rabbit monoclonal (D9E)
  • immunohistochemistry; human; fig s1
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in immunohistochemistry on human samples (fig s1). Oncotarget (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; human; loading ...; fig s3
In order to explore how extracellular translationally controlled tumor protein affects colon cancer progression, Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 4060) was used in western blot on human samples (fig s3). Oncotarget (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; fig 7
Cell Signaling Technology AKT1 antibody (Cell signaling, 4060) was used in western blot on mouse samples (fig 7). PLoS ONE (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; human; fig s4a
Cell Signaling Technology AKT1 antibody (CST, 4060S) was used in western blot on human samples (fig s4a). Nature (2016) ncbi
rabbit monoclonal (D9E)
  • immunohistochemistry - paraffin section; mouse; 1:500; loading ...; fig 4f
Cell Signaling Technology AKT1 antibody (Cell Signaling, D9E) was used in immunohistochemistry - paraffin section on mouse samples at 1:500 (fig 4f). Oncogene (2017) ncbi
rabbit monoclonal (D9E)
  • immunocytochemistry; mouse; 1:200; fig 14
  • western blot; mouse; 1:4000; fig 13
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in immunocytochemistry on mouse samples at 1:200 (fig 14) and in western blot on mouse samples at 1:4000 (fig 13). Histochem Cell Biol (2016) ncbi
rabbit polyclonal
  • western blot; mouse; 1:1000; fig 6
In order to study the attenuation of Alzheimer's pathology in mice due to kallikrein-8 inhibition, Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 9271) was used in western blot on mouse samples at 1:1000 (fig 6). Alzheimers Dement (2016) ncbi
rabbit polyclonal
  • western blot; human; loading ...; fig 3d
Cell Signaling Technology AKT1 antibody (cell signalling, 9271) was used in western blot on human samples (fig 3d). Oncotarget (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; 1:2000; fig S11
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on mouse samples at 1:2000 (fig S11). Nat Commun (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; human; fig 2a
In order to develop a patient-derived xenograft platform and use it to identify genes that contribute the cancer resistance of melanoma patients treated with BRAF inhibitors, Cell Signaling Technology AKT1 antibody (CST, 4060) was used in western blot on human samples (fig 2a). Cell Rep (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; human; 1:3000; loading ...; fig 1e
  • immunohistochemistry; mouse; 1:100; loading ...; fig 5c
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on human samples at 1:3000 (fig 1e) and in immunohistochemistry on mouse samples at 1:100 (fig 5c). Cell Rep (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; human; 1:1000; fig 4
Cell Signaling Technology AKT1 antibody (Cell Signaling, D9E XP) was used in western blot on human samples at 1:1000 (fig 4). Sci Rep (2016) ncbi
rabbit polyclonal
  • western blot; human; 1:1000; fig 3
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on human samples at 1:1000 (fig 3). Nat Commun (2016) ncbi
rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig 5d
Cell Signaling Technology AKT1 antibody (cell signalling, 9271) was used in western blot on human samples at 1:1000 (fig 5d). Oncotarget (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; human; 1:1000; fig 6A
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on human samples at 1:1000 (fig 6A). Front Pharmacol (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; fig s4
In order to determine maintenance of mouse embryonic stem cell identity by a myc-driven self-reinforcing regulatory network, Cell Signaling Technology AKT1 antibody (Cell Signalling, 4060) was used in western blot on mouse samples (fig s4). Nat Commun (2016) ncbi
rabbit polyclonal
  • western blot; human; fig 1
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on human samples (fig 1). PLoS ONE (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; loading ...; fig 7
In order to report the effects of PD-L1 modulation of T cell function in graft-versus-host disease, Cell Signaling Technology AKT1 antibody (cell signalling, D9E) was used in western blot on mouse samples (fig 7). J Clin Invest (2016) ncbi
rabbit polyclonal
  • western blot; mouse; loading ...; fig 4c
In order to characterize cardiac defects in interleukin-18 knock out mice, Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 9271) was used in western blot on mouse samples (fig 4c). Am J Physiol Heart Circ Physiol (2016) ncbi
rabbit polyclonal
  • western blot; human; loading ...; fig 3b
In order to determine how C3G controls tumorigenesis, Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on human samples (fig 3b). Oncotarget (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; loading ...; fig 1a
In order to study how myophosphorylase deficiency affects glucose metabolism in mouse models of McArdle disease and in patients with McArdle disease, Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on mouse samples (fig 1a). Am J Physiol Regul Integr Comp Physiol (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; human; fig 1
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on human samples (fig 1). J Immunol (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; fig 6
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060S) was used in western blot on mouse samples (fig 6). Proc Natl Acad Sci U S A (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; human; 1:1000; fig s4
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060S) was used in western blot on human samples at 1:1000 (fig s4). Nat Commun (2016) ncbi
rabbit polyclonal
  • western blot; human; fig 5
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on human samples (fig 5). Sci Rep (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; fig 1
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on mouse samples (fig 1). Skelet Muscle (2016) ncbi
rabbit monoclonal (D9E)
  • immunohistochemistry; rat; fig 7a
Cell Signaling Technology AKT1 antibody (Cell Signalling Technology, 4060) was used in immunohistochemistry on rat samples (fig 7a). J Cell Sci (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; human; fig 4
In order to identify and characterize two non-AUG-initiated PTEN proteoforms, Cell Signaling Technology AKT1 antibody (Cell Signalling, D9E) was used in western blot on human samples (fig 4). Open Biol (2016) ncbi
rabbit polyclonal
  • western blot; human; fig 2
In order to utilize a novel targe for type 2 diabetes and regulate the effects of GPR21, Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 9271) was used in western blot on human samples (fig 2). Sci Rep (2016) ncbi
rabbit polyclonal
  • western blot; mouse; fig 5
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on mouse samples (fig 5). Nat Cell Biol (2016) ncbi
rabbit polyclonal
  • western blot; mouse; fig 7
Cell Signaling Technology AKT1 antibody (Cell Signaling Tech, 9271S) was used in western blot on mouse samples (fig 7). PLoS ONE (2016) ncbi
rabbit polyclonal
  • western blot; human; loading ...; fig 1a
In order to investigate NF-KB signaling in natural killer cells, Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on human samples (fig 1a). Nat Commun (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; human; loading ...; fig 5c
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on human samples (fig 5c). Carcinogenesis (2016) ncbi
rabbit polyclonal
  • western blot; mouse; 1:2000; loading ...; fig 2f
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 9271) was used in western blot on mouse samples at 1:2000 (fig 2f). Diabetes (2016) ncbi
rabbit polyclonal
  • western blot; mouse; loading ...; fig 2f
In order to assess the contribution of TRIB3 to glucose-induced insulin resistance and metabolism, Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on mouse samples (fig 2f). Diabetes (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; human; 1:1000; loading ...; fig 6a
Cell Signaling Technology AKT1 antibody (cell signalling, 4060P) was used in western blot on human samples at 1:1000 (fig 6a). Oncotarget (2016) ncbi
rabbit polyclonal
  • western blot; human; 1:500; fig 6
Cell Signaling Technology AKT1 antibody (Cell Signaling Tech, 9271) was used in western blot on human samples at 1:500 (fig 6). Front Cell Infect Microbiol (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; 1:1000; fig 5
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060P) was used in western blot on mouse samples at 1:1000 (fig 5). Front Physiol (2016) ncbi
rabbit polyclonal
  • western blot; mouse; 1:1000; fig st2
Cell Signaling Technology AKT1 antibody (Cell signaling, 9271) was used in western blot on mouse samples at 1:1000 (fig st2). PLoS ONE (2016) ncbi
rabbit polyclonal
  • western blot; human; 1:1000; fig s2
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on human samples at 1:1000 (fig s2). Nat Commun (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; fig 3
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 4060) was used in western blot on mouse samples (fig 3). Sci Rep (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; human; fig 7
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on human samples (fig 7). Sci Rep (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; 1:1000; fig 4
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on mouse samples at 1:1000 (fig 4). Sci Rep (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; loading ...; fig 6a
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on mouse samples (fig 6a). Oncotarget (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; human; fig 3
In order to study promotion of survival of breast cancer cells in response to hyper-fractionated radiation treatment by RAC1 GTPase, Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on human samples (fig 3). Oncogene (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; loading ...; fig 6a
In order to elucidate the role of AMP-activated protein kinase in regulating T cell survival and function, Cell Signaling Technology AKT1 antibody (Cell signaling, 4060) was used in western blot on mouse samples (fig 6a). Oncotarget (2016) ncbi
rabbit polyclonal
  • western blot; human; loading ...; fig 4a
Cell Signaling Technology AKT1 antibody (cell signalling, 9271) was used in western blot on human samples (fig 4a). Oncotarget (2016) ncbi
rabbit polyclonal
  • western blot; mouse; 1:1000; fig s1h
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on mouse samples at 1:1000 (fig s1h). Proc Natl Acad Sci U S A (2016) ncbi
rabbit polyclonal
  • western blot; mouse; fig 4a
In order to research the effects of environmental tobacco smoke on autophagy and longevity, Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on mouse samples (fig 4a). Oncotarget (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; fig 5
Cell Signaling Technology AKT1 antibody (Cell Signaling Tech, 4060) was used in western blot on mouse samples (fig 5). Stem Cell Reports (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; 1:1000; loading ...; fig s10b
In order to use naked mole-rat-induced pluripotent stem cells to study mechanisms of cancer resistance, Cell Signaling Technology AKT1 antibody (CST, 4,060) was used in western blot on mouse samples at 1:1000 (fig s10b). Nat Commun (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; human; fig 5
In order to research a novel method of differential ligand activation and phosphatase-mediated deactivation of insulin receptor tyrosine-specific phosphorylation, Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on human samples (fig 5). Cell Signal (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; human; fig 2
In order to study a novel compound via preclinical validation that targets p70SR kinase in breast cancer, Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on human samples (fig 2). Aging (Albany NY) (2016) ncbi
rabbit polyclonal
  • western blot; human; fig 6
In order to characterize induction of apoptosis in SH-SY5Y human neuroblastoma cells through up regulation of flotillin-2 in the lipid raft and the activation of BDNF/Trkb signaling due to cholesterol overload, Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 9271) was used in western blot on human samples (fig 6). Neuroscience (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; human; fig 6e
In order to identify transcription factors involved in pancreatic ductal adenocarcinoma pathogenesis, Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060S) was used in western blot on human samples (fig 6e). Am J Physiol Gastrointest Liver Physiol (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; human; fig 6
Cell Signaling Technology AKT1 antibody (Cell Signalling, 4060) was used in western blot on human samples (fig 6). Sci Rep (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; 1:1000; loading ...; fig 7a
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on mouse samples at 1:1000 (fig 7a). J Am Heart Assoc (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; 1:1000; fig 4
Cell Signaling Technology AKT1 antibody (Cell signaling, 4060) was used in western blot on mouse samples at 1:1000 (fig 4). Diabetologia (2016) ncbi
rabbit monoclonal (D9E)
  • immunohistochemistry - paraffin section; zebrafish ; fig 6
In order to investigate mediation by the GAP-related domain in the synergy between loss of NF1 and overexpression of MYCN in neuroblastoma, Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in immunohistochemistry - paraffin section on zebrafish samples (fig 6). elife (2016) ncbi
rabbit polyclonal
  • western blot; human; fig 4
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on human samples (fig 4). BMC Complement Altern Med (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; human; 1:500; fig 4
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on human samples at 1:500 (fig 4). Mol Med Rep (2016) ncbi
rabbit monoclonal (D9E)
  • immunocytochemistry; mouse; fig 4
  • western blot; mouse; fig 1
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in immunocytochemistry on mouse samples (fig 4) and in western blot on mouse samples (fig 1). Oncotarget (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; fig 2
In order to characterize regulation of craniofacial skeletal development by canonical and noncanonical intraflagellar transport, Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on mouse samples (fig 2). Proc Natl Acad Sci U S A (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; loading ...
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on mouse samples . Am J Physiol Endocrinol Metab (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; 1:1000; fig s1
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on mouse samples at 1:1000 (fig s1). PLoS ONE (2016) ncbi
rabbit polyclonal
  • western blot; mouse; fig 3
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 9271) was used in western blot on mouse samples (fig 3). Mol Metab (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; human; 1:1000; loading ...; fig 3d
In order to identify genetic features regulating cell survival after exposure to radiation., Cell Signaling Technology AKT1 antibody (Cell Signalling, 4060P) was used in western blot on human samples at 1:1000 (fig 3d). Nat Commun (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; human; fig 5
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 4060) was used in western blot on human samples (fig 5). PLoS ONE (2016) ncbi
rabbit polyclonal
  • western blot; mouse; 1:1000; fig 3
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on mouse samples at 1:1000 (fig 3). Sci Rep (2016) ncbi
rabbit monoclonal (D9E)
  • immunohistochemistry; fruit fly; 1:800; loading ...; fig s3c
Cell Signaling Technology AKT1 antibody (Cell Signaling Technologies, 4060) was used in immunohistochemistry on fruit fly samples at 1:800 (fig s3c). Mol Psychiatry (2017) ncbi
rabbit polyclonal
  • western blot; mouse; 1:1000; fig 5
In order to research suppression of obesity in leptin-deficient mice by Tbc1d1 deletion, Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on mouse samples at 1:1000 (fig 5). Int J Obes (Lond) (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; human; loading ...; fig 2a
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on human samples (fig 2a). Oncotarget (2016) ncbi
rabbit polyclonal
  • western blot; human; fig 5
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 9271) was used in western blot on human samples (fig 5). J Cancer (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; human; fig 1
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060S) was used in western blot on human samples (fig 1). Sci Rep (2016) ncbi
rabbit polyclonal
  • western blot; rat; 1:1000; fig 5
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on rat samples at 1:1000 (fig 5). Exp Ther Med (2016) ncbi
rabbit polyclonal
  • western blot; mouse; fig 4
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on mouse samples (fig 4). PLoS ONE (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; human; loading ...; fig 1a
Cell Signaling Technology AKT1 antibody (Cell Signaling, 5012) was used in western blot on human samples (fig 1a). Oncogene (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; loading ...; fig 5c
In order to report cross-talk between mitochondrial elongation factor 4 -dependent quality control and cytoplasmic mechanistic (mammalian) target of rapamycin signaling, Cell Signaling Technology AKT1 antibody (Cell signaling, 4060) was used in western blot on mouse samples (fig 5c). Nat Struct Mol Biol (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; 1:1000; fig 5
In order to investigate inhibition of neural stem cell proliferation through Wnt/beta-catenin pathway by its GAP domain via Porf-2, Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060s) was used in western blot on mouse samples at 1:1000 (fig 5). Front Cell Neurosci (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; African green monkey; fig 3
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on African green monkey samples (fig 3). Traffic (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; fruit fly; 1:1000; fig 2a
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on fruit fly samples at 1:1000 (fig 2a). PLoS Genet (2016) ncbi
rabbit polyclonal
  • western blot; mouse; fig 5c
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 9271) was used in western blot on mouse samples (fig 5c). Cell Rep (2016) ncbi
rabbit polyclonal
  • western blot; mouse; loading ...; fig 4f
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271S) was used in western blot on mouse samples (fig 4f). MBio (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; human; loading ...; fig 7
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on human samples (fig 7). J Biol Chem (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; human; fig 4
Cell Signaling Technology AKT1 antibody (Cell Signaling Tech, 4060) was used in western blot on human samples (fig 4). PLoS ONE (2016) ncbi
rabbit polyclonal
  • western blot; human; 1:1000; fig `1
In order to study induction of pancreatic ductal cell differentiation into insulin-producing cells by preadipocyte factor 1, Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 9271) was used in western blot on human samples at 1:1000 (fig `1). Sci Rep (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; human; fig 2
Cell Signaling Technology AKT1 antibody (Cell Signaling Tech, 4060B) was used in western blot on human samples (fig 2). Biol Open (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; human; fig 5
Cell Signaling Technology AKT1 antibody (CST, 4060) was used in western blot on human samples (fig 5). Oncogenesis (2016) ncbi
rabbit polyclonal
  • western blot; human; 1:1000; fig 3
Cell Signaling Technology AKT1 antibody (Cell Signaling Technologies, 9271) was used in western blot on human samples at 1:1000 (fig 3). Nat Commun (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; 1:1000; fig 3
Cell Signaling Technology AKT1 antibody (CST, 4060) was used in western blot on mouse samples at 1:1000 (fig 3). Nat Commun (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; human; fig 7
In order to study ectodomain shedding and its role in cell function by regulation of receptor for advanced glycation end products (RAGE), Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060P) was used in western blot on human samples (fig 7). J Biol Chem (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; fig 2
In order to describe a signaling pathway from beta-adrenergic receptor and protein kinase A via mTORC1 that is required for adipose browning by catecholamines, Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on mouse samples (fig 2). J Clin Invest (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; human; 1:1000; fig 5
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on human samples at 1:1000 (fig 5). Genes Cancer (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; hamsters; loading ...; fig 3a
In order to suggest a model in which glycan-deficient prion protein, glycosaminoglycan, and vascular endothelial growth factor receptor 2 interact to alter cellular behavior, Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on hamsters samples (fig 3a). Cell Signal (2016) ncbi
rabbit monoclonal (D9E)
  • immunohistochemistry - paraffin section; mouse; fig 4
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in immunohistochemistry - paraffin section on mouse samples (fig 4). Oncotarget (2016) ncbi
rabbit polyclonal
  • western blot; human; 1:1000; fig 4
In order to elucidate the mechanisms by which L1CAM gene mutations result in neuronal defects, Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on human samples at 1:1000 (fig 4). J Exp Med (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; human; fig 1
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on human samples (fig 1). Oncogenesis (2016) ncbi
rabbit polyclonal
  • western blot; human; fig 1
Cell Signaling Technology AKT1 antibody (Cell signaling, 9271) was used in western blot on human samples (fig 1). Oncogene (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; human; fig 4
Cell Signaling Technology AKT1 antibody (Cell signaling, 4060) was used in western blot on human samples (fig 4). Oncotarget (2016) ncbi
rabbit polyclonal
  • western blot; human; loading ...; fig 4
In order to find tumor types sensitive to phosphoinositide 3-kinase pathway inhibitors, Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on human samples (fig 4). Oncotarget (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; human; fig 6
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on human samples (fig 6). Oncotarget (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; human; fig 5
In order to determine how inhibition of human glioblastoma invasion by actin polymerization can occur by an anti-depressant called fluvoxamine, Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 4060) was used in western blot on human samples (fig 5). Sci Rep (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; human; fig 4
In order to determine facilitation of chemoresistance and cancer proliferation by Haem-dependent dimerization of PGRMC1/Sigma-2 receptor, Cell Signaling Technology AKT1 antibody (Cell signaling, 4060S) was used in western blot on human samples (fig 4). Nat Commun (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; 1:1000; fig s4
In order to elucidate the mechanism of corticotropin releasing hormone (Crh) and macroautophagy, Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060P) was used in western blot on mouse samples at 1:1000 (fig s4). Sci Rep (2016) ncbi
rabbit polyclonal
  • western blot; mouse; fig 7
In order to analyze promotion of development of distinct sarcoma subtypes in hepatocyte growth factor-mediated satellite cells niche disruption, Cell Signaling Technology AKT1 antibody (Cell signaling, 9271) was used in western blot on mouse samples (fig 7). elife (2016) ncbi
rabbit polyclonal
  • western blot; mouse; 1:200; loading ...; fig 5a
In order to use Kcne3 knockout mice to investigate atrial electrophysiology and the development of aldosterone-dependent atrial fibrillation, Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on mouse samples at 1:200 (fig 5a). FASEB J (2016) ncbi
rabbit polyclonal
  • western blot; human; loading ...; fig 3a
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271S) was used in western blot on human samples (fig 3a). Int J Oncol (2016) ncbi
rabbit polyclonal
  • western blot; human; fig 5
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 9271) was used in western blot on human samples (fig 5). Sci Rep (2016) ncbi
rabbit monoclonal (D9E)
  • flow cytometry; mouse; fig 5
In order to study the requisite for the function of regulatory T cells known as phosphatase PP2A, Cell Signaling Technology AKT1 antibody (Cell Signaling, D9E) was used in flow cytometry on mouse samples (fig 5). Nat Immunol (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; fig 5
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on mouse samples (fig 5). J Clin Invest (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; fig 3
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, D9E) was used in western blot on mouse samples (fig 3). Sci Rep (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; human; loading ...; fig s8
Cell Signaling Technology AKT1 antibody (Cell Signaling, 5012) was used in western blot on human samples (fig s8). Science (2016) ncbi
rabbit polyclonal
  • immunohistochemistry - paraffin section; human; 1:50; fig s1
In order to utilize ovarian cancer xenograft models to study dynamic modulation of phosphoprotein expression, Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in immunohistochemistry - paraffin section on human samples at 1:50 (fig s1). BMC Cancer (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; human; loading ...; fig 3c
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on human samples (fig 3c). Oncotarget (2016) ncbi
rabbit polyclonal
  • western blot; zebrafish ; 1:1000; fig 2
Cell Signaling Technology AKT1 antibody (cell Signaling Tech, 9271) was used in western blot on zebrafish samples at 1:1000 (fig 2). PLoS ONE (2016) ncbi
rabbit monoclonal (D9E)
  • immunohistochemistry - paraffin section; human; 1:50; fig 4
Cell Signaling Technology AKT1 antibody (Cell Signaling Tech, 4060S) was used in immunohistochemistry - paraffin section on human samples at 1:50 (fig 4). EMBO Mol Med (2016) ncbi
rabbit polyclonal
  • western blot; mouse; fig 4
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on mouse samples (fig 4). Nat Med (2016) ncbi
rabbit polyclonal
  • western blot; mouse; 1:1000; loading ...; fig 1d
In order to test if targeting tropomysin receptor kinase B reduces radiation-induced cognitive deficits, Cell Signaling Technology AKT1 antibody (Cell signaling, 9271) was used in western blot on mouse samples at 1:1000 (fig 1d). Exp Neurol (2016) ncbi
rabbit polyclonal
  • western blot; mouse; 1:500; fig 6
In order to elucidate the favor of Smad-independent TGF-beta signaling that drives EMT in pancreatic ductal adenocarcinoma due to TAp73 loss, Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 9271) was used in western blot on mouse samples at 1:500 (fig 6). Cell Death Differ (2016) ncbi
rabbit monoclonal (D9E)
  • immunohistochemistry - paraffin section; mouse; 1:50; fig 6
  • western blot; mouse; 1:1000; fig 6
  • western blot; human; 1:1000; fig 2
Cell Signaling Technology AKT1 antibody (Cell signaling, 4060) was used in immunohistochemistry - paraffin section on mouse samples at 1:50 (fig 6), in western blot on mouse samples at 1:1000 (fig 6) and in western blot on human samples at 1:1000 (fig 2). Oncotarget (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; human; fig 5
In order to investigate the role of CHD5 in renal cell carcinoma, Cell Signaling Technology AKT1 antibody (Cell Signal, 4060) was used in western blot on human samples (fig 5). Oncotarget (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; human; 1:2000; fig 4
Cell Signaling Technology AKT1 antibody (CST, 4060) was used in western blot on human samples at 1:2000 (fig 4). Oncotarget (2016) ncbi
rabbit polyclonal
  • western blot; human; fig 6
In order to characterize multiple molecularly defined cancer indications by studying ROS1, ALK inhibitor, Entrectinib, a Pan-TRK activity, Cell Signaling Technology AKT1 antibody (Cell signaling, 9271) was used in western blot on human samples (fig 6). Mol Cancer Ther (2016) ncbi
rabbit polyclonal
  • western blot; human; fig 1b
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on human samples (fig 1b). PLoS ONE (2016) ncbi
rabbit polyclonal
  • western blot; human; 1:1000; fig 5
Cell Signaling Technology AKT1 antibody (Cell Signaling Tech, 9271) was used in western blot on human samples at 1:1000 (fig 5). Int J Mol Med (2016) ncbi
rabbit polyclonal
  • western blot; human; 1:1000; fig 5
Cell Signaling Technology AKT1 antibody (Cell Signaling Tech, 9271) was used in western blot on human samples at 1:1000 (fig 5). Mol Med Rep (2016) ncbi
rabbit polyclonal
  • western blot; human; 1:1000; loading ...; tbl s2
In order to identify glycogen synthase kinase beta and forkhead box P3 as direct PIM targets, Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on human samples at 1:1000 (tbl s2). Exp Cell Res (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; 1:1000; fig 8
In order to determine the rescue of VE-PTP-dependent restoration of Tie2 signaling from angiopoietin-2-induced blood-brain barrier compromise and increased stroke size, Cell Signaling Technology AKT1 antibody (Cell signaling, 4060S) was used in western blot on mouse samples at 1:1000 (fig 8). Acta Neuropathol (2016) ncbi
rabbit polyclonal
  • western blot; human; fig 4
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271S) was used in western blot on human samples (fig 4). Sci Rep (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; human; loading ...; fig 3g
Cell Signaling Technology AKT1 antibody (Cell signaling, 4060) was used in western blot on human samples (fig 3g). J Clin Invest (2016) ncbi
rabbit polyclonal
  • western blot; mouse; 1:2000; fig 4
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on mouse samples at 1:2000 (fig 4). Nat Commun (2016) ncbi
rabbit polyclonal
  • western blot; mouse; fig 3
In order to assess the inhibition of mammalian target of rapamycin complex 1 in mice due to fibroblast growth factor 21 improving hepatic insulin sensitivity, Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on mouse samples (fig 3). Hepatology (2016) ncbi
rabbit polyclonal
  • western blot; mouse; 1:1000; tbl 1
In order to study novelty-induced and brain-specific basal alternations in PI3K-Akt and MAPK/ERK signaling in a middle-aged A-betaPP/PS1 mouse model of Alzheimer's disease, Cell Signaling Technology AKT1 antibody (CST, 9271) was used in western blot on mouse samples at 1:1000 (tbl 1). J Alzheimers Dis (2016) ncbi
rabbit polyclonal
  • western blot; human; 1:1000; fig 3
Cell Signaling Technology AKT1 antibody (Cell Signaling Tech, 9271) was used in western blot on human samples at 1:1000 (fig 3). PLoS ONE (2016) ncbi
rabbit monoclonal (D9E)
  • flow cytometry; human; 1:5; fig 5
Cell Signaling Technology AKT1 antibody (Cell Signaling, 5315) was used in flow cytometry on human samples at 1:5 (fig 5). Oncotarget (2016) ncbi
rabbit polyclonal
  • western blot; human; 1:1000; fig 6
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on human samples at 1:1000 (fig 6). Oncotarget (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; human; fig 1d
In order to elucidate the mechanisms by which cancer cells overcome anoikis, Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 4060) was used in western blot on human samples (fig 1d). Cell Death Differ (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on mouse samples . Science (2016) ncbi
rabbit polyclonal
  • western blot; mouse; fig 7a
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on mouse samples (fig 7a). Endocrinology (2016) ncbi
rabbit polyclonal
  • western blot; rat; 1:1000; loading ...; fig 4c
Cell Signaling Technology AKT1 antibody (Cell signaling, 9271) was used in western blot on rat samples at 1:1000 (fig 4c). Sci Rep (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; human; fig 6
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on human samples (fig 6). BMC Cancer (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; fig 4
Cell Signaling Technology AKT1 antibody (CST, 4060s) was used in western blot on mouse samples (fig 4). Stem Cell Reports (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; fig 5
  • western blot; human
Cell Signaling Technology AKT1 antibody (Cell Signaling, D9E) was used in western blot on mouse samples (fig 5) and in western blot on human samples . J Exp Med (2016) ncbi
rabbit polyclonal
  • immunocytochemistry; human; 1:50; fig 2
  • western blot; human; fig s11
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in immunocytochemistry on human samples at 1:50 (fig 2) and in western blot on human samples (fig s11). Nat Commun (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; human; fig 7
In order to investigate survival and neuronal differentiation of human BM-MSCs by pulsed electromagnetic fields, Cell Signaling Technology AKT1 antibody (Cell signaling, 4060) was used in western blot on human samples (fig 7). Life Sci (2016) ncbi
rabbit monoclonal (D9E)
  • immunohistochemistry; human; 1:100; fig 4
  • western blot; human; 1:100; fig 4
Cell Signaling Technology AKT1 antibody (Cell signaling, 4060) was used in immunohistochemistry on human samples at 1:100 (fig 4) and in western blot on human samples at 1:100 (fig 4). PLoS ONE (2016) ncbi
rabbit polyclonal
  • western blot; human; loading ...; fig 2a
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 9271) was used in western blot on human samples (fig 2a). Mol Endocrinol (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; 1:1000; fig 6
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on mouse samples at 1:1000 (fig 6). Nat Commun (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; rat; 1:1000; fig 4b
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on rat samples at 1:1000 (fig 4b). Neural Plast (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; human; 1:1000; fig 7
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on human samples at 1:1000 (fig 7). Nat Commun (2016) ncbi
rabbit polyclonal
  • western blot; human; fig 4
Cell Signaling Technology AKT1 antibody (Cell signaling, 9271) was used in western blot on human samples (fig 4). Oncogene (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; human; fig 4
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 4060) was used in western blot on human samples (fig 4). Oncogene (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; human; fig 5f
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on human samples (fig 5f). Oncotarget (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; fig s5
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on mouse samples (fig s5). Oncotarget (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; human; 1:1000; fig 2
In order to study prostate cancer DU145 cells and anti-tumor activity of the TRPM8 inhibitor BCTC, Cell Signaling Technology AKT1 antibody (Cell Signaling Technologies, 4060) was used in western blot on human samples at 1:1000 (fig 2). Oncol Lett (2016) ncbi
rabbit polyclonal
  • western blot; mouse; 1:1000; loading ...; fig s10b
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on mouse samples at 1:1000 (fig s10b). Nat Commun (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; loading ...; fig 7e
Cell Signaling Technology AKT1 antibody (CST, D9E) was used in western blot on mouse samples (fig 7e). Diabetes (2016) ncbi
rabbit polyclonal
  • western blot; human; loading ...; fig 7a
In order to explore how junctional adhesion molecule family members differentially regulate CXCR4 function and CXCL12 secretion in the bone marrow niche, Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on human samples (fig 7a). Stem Cells (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; human; loading ...; fig 3c
Cell Signaling Technology AKT1 antibody (CST, 4060) was used in western blot on human samples (fig 3c). Biochim Biophys Acta (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; human; fig 3
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 4060) was used in western blot on human samples (fig 3). Cell Commun Signal (2016) ncbi
rabbit polyclonal
  • western blot; mouse; loading ...; fig 2e
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on mouse samples (fig 2e). Sci Rep (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; human; 1:1000; fig 3
  • western blot; mouse; 1:1000; fig 1
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, cst-4060) was used in western blot on human samples at 1:1000 (fig 3) and in western blot on mouse samples at 1:1000 (fig 1). Nat Cell Biol (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; 1:2500; fig 4
Cell Signaling Technology AKT1 antibody (Cell signaling technologies, 4060) was used in western blot on mouse samples at 1:2500 (fig 4). Nat Commun (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; human; fig 6
In order to determine a mechanism for regulation of tumor progression due to simultaneous activation of induced heterodimerization between cannabinoid receptor 2 (CB2) and CXCR4 chemokine receptor, Cell Signaling Technology AKT1 antibody (Cell signaling, 4060) was used in western blot on human samples (fig 6). J Biol Chem (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; human; 1:1000; fig 4
Cell Signaling Technology AKT1 antibody (Cell Signalling, D9E) was used in western blot on human samples at 1:1000 (fig 4). Sci Rep (2016) ncbi
rabbit polyclonal
  • western blot; mouse; 1:1000; fig 3b
In order to analyze the suppression of soft tissue sarcoma growth due to epigenetic re-expression of HIF-2 alpha, Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on mouse samples at 1:1000 (fig 3b). Nat Commun (2016) ncbi
rabbit polyclonal
  • western blot; mouse; fig 3
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 9271) was used in western blot on mouse samples (fig 3). Sci Rep (2016) ncbi
rabbit monoclonal (D9E)
  • immunocytochemistry; mouse; fig 6
In order to elucidate the properties of Crim1 and its cell-autonomous and paracrine roles during embryonic heart development, Cell Signaling Technology AKT1 antibody (Cell signaling, 4060) was used in immunocytochemistry on mouse samples (fig 6). Sci Rep (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; 1:1000; fig 5
In order to determine the role of Kindlin-2 tp activate integrins by cooperating with talin and induction of cell spreading by directly binding paxillin, Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on mouse samples at 1:1000 (fig 5). elife (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; human; 1:1000; fig 1
In order to investigate impairment of autophagy flux and induction of cell death independent of necroptosis and apoptosis by dual PI-3 kinase/mTOR inhibition, Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on human samples at 1:1000 (fig 1). Oncotarget (2016) ncbi
rabbit polyclonal
  • western blot; mouse; 1:1000; fig 3
In order to analyze regulation of formation of the columnar neural epithelium by the tumor suppressor PTEN and the PDK1 kinase, Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on mouse samples at 1:1000 (fig 3). elife (2016) ncbi
rabbit polyclonal
  • western blot; human; fig 3
Cell Signaling Technology AKT1 antibody (Cell Signalling, 9271) was used in western blot on human samples (fig 3). Oncotarget (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; human; fig 4
Cell Signaling Technology AKT1 antibody (Cell signaling, 4060) was used in western blot on human samples (fig 4). Mol Cancer (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; human; fig 1
  • western blot; mouse; fig 5
Cell Signaling Technology AKT1 antibody (Cell Signaling Tech, 4060) was used in western blot on human samples (fig 1) and in western blot on mouse samples (fig 5). Oncotarget (2016) ncbi
rabbit polyclonal
  • western blot; human; fig 1
In order to study how ZEB1 drives the epithelial-mesenchymal transition-related resistance to EGFR-tyrosine kinases inhibitors in non-small cell lung cancer, Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on human samples (fig 1). PLoS ONE (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; human; fig 5
In order to study the role of MAML3 in proliferation and retinoic acid-mediated differentiation, Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on human samples (fig 5). Mol Cancer Res (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; rat; 1:1000; fig 4
Cell Signaling Technology AKT1 antibody (Cell Signaling Tech, 4060) was used in western blot on rat samples at 1:1000 (fig 4). Stem Cells Int (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; 1:1000; fig 2
Cell Signaling Technology AKT1 antibody (cell Signaling Tech, 4060) was used in western blot on mouse samples at 1:1000 (fig 2). Sci Rep (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; fig 1
Cell Signaling Technology AKT1 antibody (Cell signaling, 4060) was used in western blot on mouse samples (fig 1). Cell Death Dis (2016) ncbi
rabbit polyclonal
  • western blot; mouse; 1:1000; loading ...; fig 1a
Cell Signaling Technology AKT1 antibody (Cell Signaling, cs-9271) was used in western blot on mouse samples at 1:1000 (fig 1a). EMBO Mol Med (2016) ncbi
rabbit polyclonal
  • western blot; human; 1:1000; fig 2
Cell Signaling Technology AKT1 antibody (Cell signalling, #9271) was used in western blot on human samples at 1:1000 (fig 2). Cell Mol Gastroenterol Hepatol (2016) ncbi
rabbit polyclonal
  • western blot; human; fig 7
Cell Signaling Technology AKT1 antibody (Cell signalling, 9271) was used in western blot on human samples (fig 7). Oncotarget (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; fig 1
Cell Signaling Technology AKT1 antibody (Cell signaling, 4060S) was used in western blot on mouse samples (fig 1). PLoS ONE (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; human; 1:1000; fig 5
In order to report the role for EPHA2 in the cell survival of tyrosine kinase inhibitors-resistant, EGFR-mutant lung cancers, Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 4060) was used in western blot on human samples at 1:1000 (fig 5). Cancer Res (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; 1:1000; fig 3
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on mouse samples at 1:1000 (fig 3). Nat Commun (2016) ncbi
rabbit polyclonal
  • western blot; human; 1:1000; fig 1s3j
In order to survey mTORC1 activity reguled by control of TSC2-Rheb signaling by arginine, Cell Signaling Technology AKT1 antibody (Cell Signaling Technologies, 9271) was used in western blot on human samples at 1:1000 (fig 1s3j). elife (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; human; fig 5d
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 4060) was used in western blot on human samples (fig 5d). Oncotarget (2016) ncbi
rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig 4b
In order to study 3-bromopyruvate, human colorectal cancer cells, glucose concentration, and hexokinase II expression, Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on human samples at 1:1000 (fig 4b). Biosci Rep (2016) ncbi
rabbit monoclonal (D9E)
  • immunocytochemistry; human; fig 1
  • western blot; human; fig 1
In order to study the interactions between PMCA2 and HER2 in breast cancer cells, Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 4060) was used in immunocytochemistry on human samples (fig 1) and in western blot on human samples (fig 1). Proc Natl Acad Sci U S A (2016) ncbi
rabbit polyclonal
  • western blot; human; loading ...; fig 4a
In order to present liposomal c8 ceramide as a potent anti-hepatocellular carcinoma agent, Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on human samples (fig 4a). PLoS ONE (2016) ncbi
rabbit polyclonal
  • western blot; human; 1:500; loading ...; fig 1b
In order to demonstrate that receptor tyrosine kinase-like orphan receptor 1 is a scaffold for cavin-1 and caveolin-1, Cell Signaling Technology AKT1 antibody (Cell Signalling, 9271) was used in western blot on human samples at 1:500 (fig 1b). Nat Commun (2016) ncbi
rabbit monoclonal (D9E)
  • immunohistochemistry - paraffin section; human; 1:50; fig 5
In order to determine the mechanisms of resistance to the pan-HER family inhibitor AZD8931, Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in immunohistochemistry - paraffin section on human samples at 1:50 (fig 5). Dis Model Mech (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; 1:1000; fig 2
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on mouse samples at 1:1000 (fig 2). PLoS ONE (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; rat; 1:2000; fig 4
Cell Signaling Technology AKT1 antibody (Cell Signaling Technologies, CST4060P) was used in western blot on rat samples at 1:2000 (fig 4). Mol Med Rep (2016) ncbi
rabbit monoclonal (D9E)
  • immunohistochemistry; mouse; fig st1
  • western blot; mouse; fig st1
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in immunohistochemistry on mouse samples (fig st1) and in western blot on mouse samples (fig st1). Liver Int (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; human; fig 6e
In order to study the effect of insulin on tumor necrosis factor-dependent early osteoarthritic in obesity and type 2 diabetes mellitus, Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on human samples (fig 6e). Arthritis Rheumatol (2016) ncbi
rabbit monoclonal (D9E)
  • immunohistochemistry - paraffin section; mouse; 1:500; fig 6
In order to discuss the use of the Cre-loxP system to develop models to study neurodegeneration or tumorigenesis, Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, D9E) was used in immunohistochemistry - paraffin section on mouse samples at 1:500 (fig 6). Dis Model Mech (2016) ncbi
rabbit polyclonal
  • western blot; mouse; loading ...; fig 3c
In order to study Ph-like ALL-related novel fusion kinase ATF7IP-PDGFRB and tyrosine kinase inhibitors in murine cells, Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on mouse samples (fig 3c). Exp Hematol (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; hamsters; loading ...; fig 3a
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on hamsters samples (fig 3a). J Neurochem (2016) ncbi
rabbit monoclonal (D9E)
  • flow cytometry; human; loading ...; fig s10a
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, C50B12) was used in flow cytometry on human samples (fig s10a). Mol Ther Methods Clin Dev (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; 1:1000; fig 6
In order to analyze Crim1 regulations of integrin signaling in lens development of mice, Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on mouse samples at 1:1000 (fig 6). Development (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; human; 1:2000; loading ...; fig 3c
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on human samples at 1:2000 (fig 3c). Int J Oncol (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; 1:1000; fig 3
In order to study a novel crizotinib-resistant solvent-front mutation in a patient with ROS1-rearranged lung cancer that is responsive to cabozantinib therapy, Cell Signaling Technology AKT1 antibody (Cell signaling, 4060) was used in western blot on mouse samples at 1:1000 (fig 3). Clin Cancer Res (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; human; loading ...; fig 6e
Cell Signaling Technology AKT1 antibody (Cell Signaling, D9E) was used in western blot on human samples (fig 6e). Cell Death Dis (2015) ncbi
rabbit polyclonal
  • western blot; mouse; fig 5
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on mouse samples (fig 5). J Cell Biol (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; fig 5
  • western blot; human; fig 5
Cell Signaling Technology AKT1 antibody (Cell signaling, D9E) was used in western blot on mouse samples (fig 5) and in western blot on human samples (fig 5). J Immunol (2016) ncbi
rabbit polyclonal
  • western blot; mouse; 1:500; fig 2
In order to research the dependence on WIP-mediated mTORC1 and Abl family kinases activities due to neuritic complexity of hippocampal neurons, Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 9271) was used in western blot on mouse samples at 1:500 (fig 2). Brain Behav (2015) ncbi
rabbit polyclonal
  • western blot; mouse; fig 4b
Cell Signaling Technology AKT1 antibody (CST, 9271) was used in western blot on mouse samples (fig 4b). Nat Commun (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; fig 5
In order to characterize an essential insulin effector in adipocytes called CDK4, Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 4060) was used in western blot on mouse samples (fig 5). J Clin Invest (2016) ncbi
rabbit polyclonal
  • immunohistochemistry - paraffin section; mouse; 1:50; loading ...; fig 6d
Cell Signaling Technology AKT1 antibody (Cell Signaling, cs9271s) was used in immunohistochemistry - paraffin section on mouse samples at 1:50 (fig 6d). Development (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; loading ...; fig s2
In order to study the polysialylation of CCR7, Cell Signaling Technology AKT1 antibody (cell signalling, D9E) was used in western blot on mouse samples (fig s2). Science (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; human; fig 4
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on human samples (fig 4). Cell Cycle (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; human; fig 1
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on human samples (fig 1). Sci Rep (2015) ncbi
rabbit polyclonal
  • western blot; mouse; 1:1000; loading ...; fig 5a
Cell Signaling Technology AKT1 antibody (Cell signaling, 9271) was used in western blot on mouse samples at 1:1000 (fig 5a). Sci Rep (2015) ncbi
rabbit polyclonal
  • western blot; mouse; fig 3
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 9271S) was used in western blot on mouse samples (fig 3). Stem Cell Reports (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; human; 1:500; fig 5
Cell Signaling Technology AKT1 antibody (Cell signaling, 4060S) was used in western blot on human samples at 1:500 (fig 5). Oncol Lett (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; human; 1:1000; tbl 1
In order to study inhibition of the FAK/PI3K/Akt/mTOR signaling pathway through av-beta-3 integrin interaction by the anti-tumor NC1 domain of collagen XIX, Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on human samples at 1:1000 (tbl 1). Oncotarget (2016) ncbi
rabbit polyclonal
  • western blot; mouse; 1:1000; fig 3
In order to test if GATA5 is a regulator of blood pressure, Cell Signaling Technology AKT1 antibody (Cell Signalling, 9271) was used in western blot on mouse samples at 1:1000 (fig 3). Nat Commun (2015) ncbi
rabbit polyclonal
  • western blot; human; fig 1
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 9271) was used in western blot on human samples (fig 1). Oncogene (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; human; fig 5
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on human samples (fig 5). Oncogene (2016) ncbi
rabbit polyclonal
  • western blot; mouse; fig 3E
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 9271) was used in western blot on mouse samples (fig 3E). Sci Rep (2015) ncbi
rabbit polyclonal
  • western blot; human; loading ...; fig s2b
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on human samples (fig s2b). Sci Adv (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; human; fig 5
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on human samples (fig 5). PLoS ONE (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; human; fig 2
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on human samples (fig 2). Sci Rep (2015) ncbi
rabbit polyclonal
  • western blot; human; loading ...; fig 3a
Cell Signaling Technology AKT1 antibody (Cell signaling, 9271) was used in western blot on human samples (fig 3a). Oncotarget (2016) ncbi
rabbit polyclonal
  • western blot; mouse; fig 7
Cell Signaling Technology AKT1 antibody (Cell Signalling, 9271) was used in western blot on mouse samples (fig 7). Biochem Pharmacol (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; human; 1:1000; fig 9
In order to investigate how lactate affects neuron metabolism, Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 4060) was used in western blot on human samples at 1:1000 (fig 9). Biochem Pharmacol (2016) ncbi
rabbit polyclonal
  • western blot; mouse; fig 3
Cell Signaling Technology AKT1 antibody (Cell Signaling Tech, 9271) was used in western blot on mouse samples (fig 3). Oncogene (2016) ncbi
rabbit polyclonal
  • western blot; human; fig 1
Cell Signaling Technology AKT1 antibody (Cell signaling, 9271) was used in western blot on human samples (fig 1). Biochem Biophys Res Commun (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; 1:100; fig 5
Cell Signaling Technology AKT1 antibody (Cell signaling, 4060) was used in western blot on mouse samples at 1:100 (fig 5). Genes Dev (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; loading ...; fig 3h
In order to study the roles caspase-11 and caspase-12 in obesity and insulin resistance, Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on mouse samples (fig 3h). J Immunol (2016) ncbi
rabbit polyclonal
  • western blot; human; fig S3
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on human samples (fig S3). Oncotarget (2016) ncbi
rabbit polyclonal
  • western blot; human; fig 3
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on human samples (fig 3). Oncotarget (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; human; 1:1000; loading ...; fig 1a
In order to evaluate the use of phenformin with MLN0128 as a treatment strategy for non-small cell lung carcinoma, Cell Signaling Technology AKT1 antibody (Cell signaling, 4060) was used in western blot on human samples at 1:1000 (fig 1a). Cancer Res (2015) ncbi
rabbit polyclonal
  • western blot; rat; 1:1000; fig 6
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on rat samples at 1:1000 (fig 6). Mol Med Rep (2016) ncbi
rabbit polyclonal
  • western blot; dog; fig 1d
In order to discover the mRNA and miRNA involved in epithelial-mesenchymal transition in MDCK cells, Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on dog samples (fig 1d). BMC Genomics (2015) ncbi
rabbit monoclonal (D9E)
  • immunohistochemistry; mouse; fig 5
  • western blot; mouse; fig 5
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in immunohistochemistry on mouse samples (fig 5) and in western blot on mouse samples (fig 5). Sci Rep (2015) ncbi
rabbit monoclonal (D9E)
  • immunocytochemistry; human; 1:1000; fig 6
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in immunocytochemistry on human samples at 1:1000 (fig 6). Nat Commun (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; dog; 1:2000; fig 5
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060P) was used in western blot on dog samples at 1:2000 (fig 5). PLoS ONE (2015) ncbi
rabbit polyclonal
  • western blot; human; fig 4
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on human samples (fig 4). BMC Cancer (2015) ncbi
rabbit polyclonal
  • western blot; mouse; fig 1
  • western blot; human; fig 1
In order to study how DNAM-1 controls NK cell-mediated cytotoxicity and cytokine production, Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 9271) was used in western blot on mouse samples (fig 1) and in western blot on human samples (fig 1). J Exp Med (2015) ncbi
rabbit monoclonal (D9E)
  • flow cytometry; human; fig 2
  • western blot; human; fig 2
In order to elucidate the contribution of leukemogenic Ras signals, Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in flow cytometry on human samples (fig 2) and in western blot on human samples (fig 2). Oncogene (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; human; 1:1000; fig 7e
In order to test if ado-trastuzumab emtansine overcomes trastuzumab resistance in murine models of brain metastases, Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on human samples at 1:1000 (fig 7e). J Natl Cancer Inst (2016) ncbi
rabbit polyclonal
  • western blot; rat; fig 5
In order to investigate the effect of heat shock on glucose metabolism by skeletal muscles, Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 9271) was used in western blot on rat samples (fig 5). Physiol Rep (2015) ncbi
rabbit polyclonal
  • western blot; human; fig 7
In order to determine promotion of cell migration and lymph node metastasis of oral squamous cell carcinoma cells by requirement of integrin beta1 and insulin-like growth factor-independent insulin-like growth factor binding protein 3, Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on human samples (fig 7). Oncotarget (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; human; 1:1000; fig 2
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on human samples at 1:1000 (fig 2). PLoS ONE (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; fig 5
In order to investigate changes to AURKA signaling after treatment with erlotinib/alisertib combination therapy, Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on mouse samples (fig 5). Front Oncol (2015) ncbi
rabbit polyclonal
  • western blot; human; 1:100; fig s7
In order to analyze organotropic metasistasis and tumour exosome integrins, Cell Signaling Technology AKT1 antibody (Cell signaling, 9271) was used in western blot on human samples at 1:100 (fig s7). Nature (2015) ncbi
rabbit polyclonal
  • western blot; rat; 1:1000; fig 1
In order to assess how chronic cerebral hypoperfusion and repeated low-dose progesterone treatment affect neurodegenerative processes and behavior, Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 9271S) was used in western blot on rat samples at 1:1000 (fig 1). Neuroscience (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; fig 6
In order to determine the role of autophagy in the regulation of liver regeneration after partial hepatectomy, Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 4060) was used in western blot on mouse samples (fig 6). Sci Rep (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; fig 2
  • western blot; human; fig 4b
In order to study a non-small-cell lung cancer and relevant EGFR mutants in an in vitro model to determine mutation specificity of EGFR tyrosine kinase inhibitors, Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 4060) was used in western blot on mouse samples (fig 2) and in western blot on human samples (fig 4b). Oncotarget (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; rat
In order to examine the Nrf2-potentiating mechanism of morin and its possible role in intervening PHLPP2-regulated Akt/GSK3beta/Fyn kinase axis, Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 4060) was used in western blot on rat samples . Redox Biol (2015) ncbi
rabbit polyclonal
  • western blot; mouse; fig 2
In order to characterize postmortem behavior and the rapid alteration of protein phosphorylation, Cell Signaling Technology AKT1 antibody (Cell signaling, 9271) was used in western blot on mouse samples (fig 2). Sci Rep (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; human; 1:1000; fig 6
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 4060) was used in western blot on human samples at 1:1000 (fig 6). Cancer Sci (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; human; 1:1000
In order to assess the impact of heat shock protein 90 inhibition in combination with focal adhesion kinase inhibitor on the growth of non-small cell lung cancer cells, Cell Signaling Technology AKT1 antibody (Cell Signaling Technologies, 4060) was used in western blot on human samples at 1:1000. Oncoscience (2015) ncbi
rabbit polyclonal
  • western blot; mouse; loading ...; fig 1a
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology., 9271) was used in western blot on mouse samples (fig 1a). J Biol Chem (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; human; fig 2
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on human samples (fig 2). Mol Cancer (2015) ncbi
rabbit polyclonal
  • western blot; human; 1:1000; fig 5
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on human samples at 1:1000 (fig 5). PLoS ONE (2015) ncbi
rabbit polyclonal
  • western blot; human; 1:1000; fig 6
Cell Signaling Technology AKT1 antibody (Cell signaling, 9271) was used in western blot on human samples at 1:1000 (fig 6). Oncotarget (2016) ncbi
rabbit polyclonal
  • western blot; human; 1:500; fig s2
In order to identify the mechanism for apoptosis in colon cancer cells after depletion of PTEN, Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 9271) was used in western blot on human samples at 1:500 (fig s2). PLoS ONE (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse
Cell Signaling Technology AKT1 antibody (CST, 4060) was used in western blot on mouse samples . Nature (2015) ncbi
rabbit polyclonal
  • western blot; mouse; fig 1
In order to assess the effects of n-3PUFA on fatty acid metabolism and insulin sensitivity in muscle cells, Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 9271) was used in western blot on mouse samples (fig 1). Biochim Biophys Acta (2016) ncbi
rabbit polyclonal
  • western blot; human; loading ...; fig 5a
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on human samples (fig 5a). Oncogene (2016) ncbi
rabbit monoclonal (D9E)
  • immunohistochemistry; mouse; 1:100; fig 8e-h
In order to analyze NFATc1 and its promotion of prostate tumorigenesis and its ability to overcome PTEN loss-induced senescence, Cell Signaling Technology AKT1 antibody (Cell Signaling Technologies, 4060 s) was used in immunohistochemistry on mouse samples at 1:100 (fig 8e-h). Oncogene (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; human; 1:500; fig s14b
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 4060) was used in western blot on human samples at 1:500 (fig s14b). J Biol Chem (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; human; 1:1000; fig s5
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060S) was used in western blot on human samples at 1:1000 (fig s5). PLoS Pathog (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; rat; fig 3
  • western blot; mouse; fig 5
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on rat samples (fig 3) and in western blot on mouse samples (fig 5). Cell Death Differ (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; fig 3
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on mouse samples (fig 3). Aging Cell (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; human; 1:1000; loading ...; fig 11
Cell Signaling Technology AKT1 antibody (Cell Signaling, D9E) was used in western blot on human samples at 1:1000 (fig 11). Anticancer Agents Med Chem (2016) ncbi
rabbit polyclonal
  • western blot; human; fig 6c
In order to elucidate the contribution of SPRY2 to colon cancer, Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on human samples (fig 6c). Oncogene (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; human; 1:2000; fig 4b
In order to characterize two clones from triple negative breast MDA-MB-231 cancer cells, Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on human samples at 1:2000 (fig 4b). Exp Cell Res (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; human; fig 1
Cell Signaling Technology AKT1 antibody (Cell signaling, D9E) was used in western blot on human samples (fig 1). Glycobiology (2016) ncbi
rabbit polyclonal
  • western blot; human; fig 3
In order to assess JNK-dependent alternative splicing in T-cell activation through CELF2-mediated regulation of MKK7, Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on human samples (fig 3). Genes Dev (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; human
In order to examine the role of asporin in the early stages of eye development in Xenopus embryos, Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 4060) was used in western blot on human samples . Development (2015) ncbi
rabbit monoclonal (D9E)
  • immunohistochemistry - paraffin section; mouse; 1:400; loading ...; fig 2a
  • western blot; mouse; loading ...; fig 2b
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in immunohistochemistry - paraffin section on mouse samples at 1:400 (fig 2a) and in western blot on mouse samples (fig 2b). Oncogenesis (2015) ncbi
rabbit polyclonal
  • western blot; human; fig S2
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 9271) was used in western blot on human samples (fig S2). PLoS ONE (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; human; loading ...; fig 4c
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on human samples (fig 4c). Oncogene (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; rat; 1:1000; fig 8
In order to investigate the role of baclofen on hippocampal CA1 pyramidal cells and its effect on reversing neuronal cell damage under chronic cerebral hyperprofusion, Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on rat samples at 1:1000 (fig 8). Sci Rep (2015) ncbi
rabbit polyclonal
  • western blot; mouse; fig 6
Cell Signaling Technology AKT1 antibody (Cell signaling, 9271) was used in western blot on mouse samples (fig 6). Sci Rep (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; human; 1:500; fig 4
In order to discuss the use of proteins and microRNA as treatments for cervical cancers, Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 4060) was used in western blot on human samples at 1:500 (fig 4). Diagn Pathol (2015) ncbi
rabbit polyclonal
  • western blot; human; 1:2000; loading ...; fig 3
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on human samples at 1:2000 (fig 3). PLoS ONE (2015) ncbi
rabbit polyclonal
  • western blot; mouse; fig 2
  • western blot; human; fig 3
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 9271) was used in western blot on mouse samples (fig 2) and in western blot on human samples (fig 3). Redox Biol (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; rat; fig 2
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 4060) was used in western blot on rat samples (fig 2). J Nutr (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; human; 1:2000; fig 4
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 4060) was used in western blot on human samples at 1:2000 (fig 4). Nat Commun (2015) ncbi
rabbit polyclonal
  • western blot; mouse; fig 6
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on mouse samples (fig 6). Autophagy (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; human; 1:1000; loading ...; fig 7b
Cell Signaling Technology AKT1 antibody (Cell Signaling, D9E) was used in western blot on human samples at 1:1000 (fig 7b). J Cell Biol (2015) ncbi
rabbit polyclonal
  • western blot; mouse; 1:1000; fig s7d
Cell Signaling Technology AKT1 antibody (Cell Signaling technologies, 9271) was used in western blot on mouse samples at 1:1000 (fig s7d). Nat Med (2015) ncbi
rabbit polyclonal
  • western blot; human; fig 7a
In order to demonstrate that LRIG1 functions as a growth suppressor in breast cancer cells, Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 9271) was used in western blot on human samples (fig 7a). Oncogene (2016) ncbi
rabbit polyclonal
  • western blot; rat; 1:1000; fig 1i
In order to identify novel molecules in peripheral myelination by spatial mapping of juxtacrine axo-glial interactions, Cell Signaling Technology AKT1 antibody (Cell Signalling, 9271) was used in western blot on rat samples at 1:1000 (fig 1i). Nat Commun (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; 1:1000; fig s5
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on mouse samples at 1:1000 (fig s5). Nat Commun (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; 1:4000; fig s3
In order to analyze regulation of radial glial scaffold development by FstI1, Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 4060) was used in western blot on mouse samples at 1:4000 (fig s3). Mol Brain (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; human; 1:1000
In order to discuss the sensitivity and selectivity of seven ROS1 and/or ALK inhibitors, Cell Signaling Technology AKT1 antibody (CST, 4060) was used in western blot on human samples at 1:1000. Proc Natl Acad Sci U S A (2015) ncbi
rabbit polyclonal
  • western blot; human; fig 5
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on human samples (fig 5). Eur Neuropsychopharmacol (2015) ncbi
rabbit polyclonal
  • western blot; human; fig 4
Cell Signaling Technology AKT1 antibody (Cell signaling, 9271) was used in western blot on human samples (fig 4). Oncogene (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; human; fig 4a
In order to characterize enhancement of tumorigenesis and metastasis of breast cancer cells by downregulating c-Cbl and Cbl-b by H19 non coding RNA-derived miR-675, Cell Signaling Technology AKT1 antibody (Cell signaling, 4060S) was used in western blot on human samples (fig 4a). Oncotarget (2015) ncbi
rabbit polyclonal
  • western blot; human; loading ...; fig 5e
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on human samples (fig 5e). BMC Cancer (2015) ncbi
rabbit polyclonal
  • western blot; mouse; fig s2
In order to analyze myogenic differentiation promotion by syntaxin 4 regulation on the surface localization of Cdo, a promyogenic receptor, Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 9271) was used in western blot on mouse samples (fig s2). Skelet Muscle (2015) ncbi
rabbit polyclonal
  • western blot; mouse; 1:1000; fig 5
  • western blot; human; 1:1000; fig s1
Cell Signaling Technology AKT1 antibody (Cell signaling, 9271) was used in western blot on mouse samples at 1:1000 (fig 5) and in western blot on human samples at 1:1000 (fig s1). Sci Rep (2015) ncbi
rabbit polyclonal
  • western blot; human; loading ...; fig 3c
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on human samples (fig 3c). BMC Cancer (2015) ncbi
rabbit polyclonal
  • western blot; human; fig 4b
In order to generate and characterize a human myeloma cell line, Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 9271) was used in western blot on human samples (fig 4b). Int J Hematol (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; rat; 1:1000
In order to study how activation of mGluR2/3 affects NMDAR function, Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 4060S) was used in western blot on rat samples at 1:1000. Exp Neurol (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; rat; loading ...; fig 3a
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on rat samples (fig 3a). Cell Mol Neurobiol (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; human; loading ...; fig 3a
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on human samples (fig 3a). J Biol Chem (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; 1:2000; fig 4
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060S) was used in western blot on mouse samples at 1:2000 (fig 4). J Biol Chem (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; human; loading ...; fig 1a
In order to report the effect of c-Met inhibition using neuroendocrine tumor cells, Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on human samples (fig 1a). Neuroendocrinology (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; human; fig 1a
In order to evaluate the use of a pan-PI3K inhibitor in chronic lymphocytic leukemia patients, Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on human samples (fig 1a). Leukemia (2016) ncbi
rabbit polyclonal
  • western blot; human; fig 2
Cell Signaling Technology AKT1 antibody (Cell signaling, 9271) was used in western blot on human samples (fig 2). J Cell Biol (2015) ncbi
rabbit polyclonal
  • western blot; human; fig 1
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on human samples (fig 1). Drug Des Devel Ther (2015) ncbi
rabbit polyclonal
  • western blot; mouse; fig 6g
Cell Signaling Technology AKT1 antibody (CellSignalingTechnology, 9271) was used in western blot on mouse samples (fig 6g). Int J Obes (Lond) (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; human; fig 6
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on human samples (fig 6). Oncotarget (2015) ncbi
rabbit polyclonal
  • western blot; mouse; 1:300
In order to elucidate the role of IL-33/IL-33 receptor signaling in mouse models of neuropathic pain, Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 9271) was used in western blot on mouse samples at 1:300. FASEB J (2016) ncbi
rabbit polyclonal
  • western blot; human; loading ...; fig 6b
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on human samples (fig 6b). BMC Cancer (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; human; 1:1000; loading ...; fig 6a
Cell Signaling Technology AKT1 antibody (Cell Signal, D9E) was used in western blot on human samples at 1:1000 (fig 6a). Diagn Pathol (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; dog; 1:1000; fig 6a
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 4060) was used in western blot on dog samples at 1:1000 (fig 6a). Nat Commun (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; 1:1000; fig 3f
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060S) was used in western blot on mouse samples at 1:1000 (fig 3f). J Cell Sci (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; fig 3
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on mouse samples (fig 3). Cancer Sci (2015) ncbi
rabbit polyclonal
  • western blot; mouse; 1:1000; fig 5
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on mouse samples at 1:1000 (fig 5). Stem Cell Reports (2015) ncbi
rabbit monoclonal (D9E)
  • immunohistochemistry - paraffin section; human; loading ...; fig 5
  • western blot; human; loading ...; fig 4a
Cell Signaling Technology AKT1 antibody (Cell signaling, 4060) was used in immunohistochemistry - paraffin section on human samples (fig 5) and in western blot on human samples (fig 4a). Mol Med Rep (2015) ncbi
rabbit polyclonal
  • western blot; rat; 1:1000; loading ...; fig 5a
Cell Signaling Technology AKT1 antibody (Cell signaling, 9271) was used in western blot on rat samples at 1:1000 (fig 5a). J Neurooncol (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; human; 1:2000
In order to study the insulin/IGF1 signaling pathway in human astrocytes, Cell Signaling Technology AKT1 antibody (CST, 4060) was used in western blot on human samples at 1:2000. Mol Brain (2015) ncbi
rabbit polyclonal
  • western blot; African green monkey; 1:500; loading ...; fig 6b
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on African green monkey samples at 1:500 (fig 6b). Nat Commun (2015) ncbi
rabbit polyclonal
  • western blot; human; 1:1000; fig s8c
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on human samples at 1:1000 (fig s8c). Mol Cancer (2015) ncbi
rabbit polyclonal
  • western blot; mouse; fig s8
In order to study induction of sarcomatoid phenotype solely due to ductal activation of oncogenic KRAS, Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on mouse samples (fig s8). Sci Rep (2015) ncbi
rabbit monoclonal (D9E)
  • immunohistochemistry - paraffin section; human; 1:100; fig 3
  • western blot; human; fig 3
In order to assess the activity of a novel dual PI3K/mTOR inhibitor on mesothelioma, Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in immunohistochemistry - paraffin section on human samples at 1:100 (fig 3) and in western blot on human samples (fig 3). PLoS ONE (2015) ncbi
rabbit polyclonal
  • other; mouse; 1:1000; fig s1
In order to identify host signaling dynamics upon Burkholderia spp. infection by a reverse-phase protein microarray-based screen, Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in other on mouse samples at 1:1000 (fig s1). Front Microbiol (2015) ncbi
rabbit polyclonal
  • western blot; mouse
In order to test if FADD participates in the activation of ligand-gated ion channels, Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on mouse samples . Eur Neuropsychopharmacol (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; human
In order to assess the role of Galphaq/11 in VEGF-dependent regulation of vascular permeability and angiogenesis, Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on human samples . Cardiovasc Res (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; human; loading ...; fig e7a
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, D9E) was used in western blot on human samples (fig e7a). Nature (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; fig 3
In order to analyze infertility in mice by deletion of the tyrosine phosphatase Shp2 in Sertoli cells, Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 4060) was used in western blot on mouse samples (fig 3). Sci Rep (2015) ncbi
rabbit polyclonal
  • western blot; human
In order to study the role of ADAM17 in cellular senescence and senescence secretome, Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 9271) was used in western blot on human samples . Breast Cancer Res (2015) ncbi
rabbit polyclonal
  • western blot; human; 1:1000
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 9271) was used in western blot on human samples at 1:1000. Int J Mol Med (2015) ncbi
rabbit polyclonal
  • western blot; mouse; fig 9a
In order to report that focal adhesion kinase phosphorylates PTEN, Cell Signaling Technology AKT1 antibody (New England Biolabs, 9271) was used in western blot on mouse samples (fig 9a). FASEB J (2015) ncbi
rabbit polyclonal
  • western blot; rat; fig S3
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on rat samples (fig S3). PLoS ONE (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; 1:1000; fig 1
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 4060) was used in western blot on mouse samples at 1:1000 (fig 1). Nat Commun (2015) ncbi
rabbit monoclonal (D9E)
  • immunocytochemistry; human; fig s6
In order to elucidate the mechanism by which NHE-1 expression is inhibited by JAK2V617F, Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060S) was used in immunocytochemistry on human samples (fig s6). Oncogene (2016) ncbi
rabbit polyclonal
  • western blot; human
In order to study the role of caspase-3-p120-RasGAP in cellular stress response, Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on human samples . J Cell Sci (2015) ncbi
rabbit polyclonal
  • western blot; scFv; fig 3
In order to elucidate the mechanism by which IFN-beta1b suppresses relapsing-remitting multiple sclerosis, Cell Signaling Technology AKT1 antibody (Cell Signalling Technology, 9271) was used in western blot on scFv samples (fig 3). Clin Exp Immunol (2015) ncbi
rabbit monoclonal (D9E)
  • immunohistochemistry - paraffin section; mouse; 1:80; fig s1a
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in immunohistochemistry - paraffin section on mouse samples at 1:80 (fig s1a). Nat Commun (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; 1:2000
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on mouse samples at 1:2000. Mol Oncol (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; human; loading ...; fig 4a
Cell Signaling Technology AKT1 antibody (Cell signaling, D9E) was used in western blot on human samples (fig 4a). Mar Drugs (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; human; 1:500; fig 3
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on human samples at 1:500 (fig 3). Cancer Biol Ther (2015) ncbi
rabbit polyclonal
  • western blot; rat; 1:1000; loading ...; fig 3a
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on rat samples at 1:1000 (fig 3a). BMC Complement Altern Med (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; rat; 1:1000; fig 1
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060X) was used in western blot on rat samples at 1:1000 (fig 1). Exp Cell Res (2015) ncbi
rabbit polyclonal
  • western blot; human; 1:2000; fig 1c
  • western blot; mouse; fig 1b
Cell Signaling Technology AKT1 antibody (Cell SignalinG, 9271) was used in western blot on human samples at 1:2000 (fig 1c) and in western blot on mouse samples (fig 1b). Nat Commun (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; human
In order to discuss detection of colorectal cancer using conventional wide-field endoscopy, Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 4060P) was used in western blot on human samples . Clin Transl Gastroenterol (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; human; fig 3
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060S) was used in western blot on human samples (fig 3). PLoS ONE (2015) ncbi
rabbit polyclonal
  • western blot; human
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on human samples . J Biomed Sci (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; human; fig 4d
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on human samples (fig 4d). Oncotarget (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; rat; 1:2000
Cell Signaling Technology AKT1 antibody (Cell Signaling, #4060) was used in western blot on rat samples at 1:2000. Int J Neuropsychopharmacol (2015) ncbi
rabbit monoclonal (D9E)
  • flow cytometry; mouse; loading ...; fig 3h
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, D9E) was used in flow cytometry on mouse samples (fig 3h). J Immunol (2015) ncbi
rabbit polyclonal
  • immunohistochemistry - free floating section; rat
In order to report that autophagy is activated to counteract the harmful effect caused by manganese, Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 9271) was used in immunohistochemistry - free floating section on rat samples . Free Radic Biol Med (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; human; fig 5
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on human samples (fig 5). Nat Immunol (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; human; 1:1000; fig 2.e
Cell Signaling Technology AKT1 antibody (CellSignaling, 4060) was used in western blot on human samples at 1:1000 (fig 2.e). Nat Cell Biol (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; human; fig 3
Cell Signaling Technology AKT1 antibody (Cell Signaling Tech, 4060) was used in western blot on human samples (fig 3). EMBO J (2015) ncbi
rabbit monoclonal (D9E)
  • flow cytometry; mouse
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 5315) was used in flow cytometry on mouse samples . Am J Physiol Lung Cell Mol Physiol (2015) ncbi
rabbit polyclonal
  • western blot; human; fig 5
Cell Signaling Technology AKT1 antibody (Cell Signalling, 9271) was used in western blot on human samples (fig 5). Int J Mol Med (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse
In order to assess the role of receptor-interacting protein 2 in VEGF signalling and myocardial ischaemia/reperfusion injury, Cell Signaling Technology AKT1 antibody (Cell Signalling Technologies, 4060) was used in western blot on mouse samples . Cardiovasc Res (2015) ncbi
rabbit polyclonal
  • western blot; human; fig 2
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271S) was used in western blot on human samples (fig 2). J Biomed Sci (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; human; 1:1000; fig 1e
In order to investigate factors involved in the crosstalk between basal cells and endothelial cells, Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 4060) was used in western blot on human samples at 1:1000 (fig 1e). J Cell Sci (2015) ncbi
rabbit monoclonal (D9E)
  • immunohistochemistry; human; loading ...; fig 2c
  • western blot; mouse; loading ...; fig 1d
Cell Signaling Technology AKT1 antibody (Cell Signaling, D9E) was used in immunohistochemistry on human samples (fig 2c) and in western blot on mouse samples (fig 1d). EMBO Rep (2015) ncbi
rabbit monoclonal (D9E)
  • immunohistochemistry - frozen section; zebrafish ; 1:50; fig 9
In order to describe the Zebrafish Integument Project, Cell Signaling Technology AKT1 antibody (Cell signaling, 4060) was used in immunohistochemistry - frozen section on zebrafish samples at 1:50 (fig 9). PLoS ONE (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; human; 1:2000; fig 7
Cell Signaling Technology AKT1 antibody (Cell-Signaling Technologies, 4060) was used in western blot on human samples at 1:2000 (fig 7). PLoS Pathog (2015) ncbi
rabbit polyclonal
  • immunohistochemistry; mouse
  • western blot; mouse
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 9271) was used in immunohistochemistry on mouse samples and in western blot on mouse samples . Mol Neurodegener (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; 1:1000; fig s4
In order to study modulation of the composition of the gut microbiota by ganoderma lucidum that reduces obesity in mice, Cell Signaling Technology AKT1 antibody (Cell signaling, 4060L) was used in western blot on mouse samples at 1:1000 (fig s4). Nat Commun (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; 1:1000; fig s9
Cell Signaling Technology AKT1 antibody (Cell signaling, 4060) was used in western blot on mouse samples at 1:1000 (fig s9). Nat Commun (2015) ncbi
rabbit polyclonal
  • western blot; human; 1:1000
In order to show that tamoxifen prevents myofibroblast differentiation, Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on human samples at 1:1000. J Cell Physiol (2015) ncbi
rabbit polyclonal
  • western blot; human; fig 5
Cell Signaling Technology AKT1 antibody (Cell Signaling Tech, 9271) was used in western blot on human samples (fig 5). Oncotarget (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; human; fig 1
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on human samples (fig 1). EBioMedicine (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; human; fig 2
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on human samples (fig 2). Oncotarget (2015) ncbi
rabbit polyclonal
  • western blot; human; 1:1000
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271s) was used in western blot on human samples at 1:1000. Am J Physiol Endocrinol Metab (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; human; fig 3
Cell Signaling Technology AKT1 antibody (Cell signaling, 4060) was used in western blot on human samples (fig 3). MAbs (2015) ncbi
rabbit polyclonal
  • western blot; mouse; fig 5
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on mouse samples (fig 5). EMBO Mol Med (2015) ncbi
rabbit monoclonal (D9E)
  • immunocytochemistry; human; 1:50; fig 4
In order to describe the proxHCR method for the detection of protein interactions and posttranslational modifications in microscopy and flow cytometry, Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in immunocytochemistry on human samples at 1:50 (fig 4). Nat Commun (2015) ncbi
rabbit polyclonal
  • western blot; human; fig 6
In order to assess the effect of Roux-en-Y gastric bypass surgery on expression and regulation of proteins involved in regulation of peripheral glucose metabolism, Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 9271) was used in western blot on human samples (fig 6). Am J Physiol Regul Integr Comp Physiol (2015) ncbi
rabbit polyclonal
  • western blot; mouse; fig 4b
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 9271) was used in western blot on mouse samples (fig 4b). J Cell Biol (2015) ncbi
rabbit polyclonal
  • western blot; human
In order to characterize nine mutations in the receptor tyrosine kinase ERBB4 identified in lung adenocarcinoma, Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 9271) was used in western blot on human samples . Oncogene (2016) ncbi
rabbit polyclonal
  • western blot; human
In order to analyze the increase of functional expression of the glutamate transporter excitatory amino acid transporter 2 (EAAT2) by peroxisome proliferator activated receptor gamma agonist pioglitazone in human glioblastoma cells, Cell Signaling Technology AKT1 antibody (Cell Signalling Technology, 9271) was used in western blot on human samples . Oncotarget (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; human; 1:1000; fig 4
In order to develop and characterize patient-derived primary xenografts to a model of muscle invasive bladder cancer, Cell Signaling Technology AKT1 antibody (Cell Signalling, 4060) was used in western blot on human samples at 1:1000 (fig 4). Oncotarget (2015) ncbi
rabbit polyclonal
  • western blot; human; loading ...; fig 2a,2b,3a-c,3e
In order to study mechanisms that confer resistance to therapeutic interventions in the insulin-like growth factor receptor pathway, Cell Signaling Technology AKT1 antibody (CST, 9271) was used in western blot on human samples (fig 2a,2b,3a-c,3e). Mol Cancer (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; fig 5
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060S) was used in western blot on mouse samples (fig 5). Am J Physiol Renal Physiol (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; human; 1:500
In order to determine if miRNA that target Muc1 are protective against pancreatic cancer, Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on human samples at 1:500. Biochim Biophys Acta (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; rat; fig 3
Cell Signaling Technology AKT1 antibody (Cell signaling, 4060s) was used in western blot on rat samples (fig 3). Int J Mol Med (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; fig 1b
In order to demonstrate that phosphorylation of PDE3B by Akt is not required for insulin to suppress adipocyte lipolysis, Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 4060S) was used in western blot on mouse samples (fig 1b). Mol Cell Biol (2015) ncbi
rabbit monoclonal (D9E)
  • immunohistochemistry; dog; fig 4
In order to compare human annd canine spontaneous head and neck squamous cell carcinoma similarities at the molecular level, Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in immunohistochemistry on dog samples (fig 4). PLoS Genet (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; fig 5
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on mouse samples (fig 5). PLoS ONE (2015) ncbi
rabbit polyclonal
  • western blot; mouse; 1:250
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 9271) was used in western blot on mouse samples at 1:250. Biochim Biophys Acta (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; 1:200; fig 2
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on mouse samples at 1:200 (fig 2). PLoS ONE (2015) ncbi
rabbit polyclonal
  • western blot; human; 1:1000; fig 5c
In order to analyze proliferation and homing of multiple myeloma cells promoted by the cyclophilin A-CD147 complex, Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 9271) was used in western blot on human samples at 1:1000 (fig 5c). Nat Med (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; human; fig 1
Cell Signaling Technology AKT1 antibody (Cell Signaling Tech, 4060s) was used in western blot on human samples (fig 1). Int J Mol Med (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; fig 4
In order to test the effects of high fat diet using a mouse model of familial Alzheimer disease, Cell Signaling Technology AKT1 antibody (Cell signaling, 4060P) was used in western blot on mouse samples (fig 4). Biochim Biophys Acta (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; human; 1:2000; fig 1b
Cell Signaling Technology AKT1 antibody (Cell Signalling, 4060) was used in western blot on human samples at 1:2000 (fig 1b). Nat Commun (2015) ncbi
rabbit polyclonal
  • western blot; mouse; 1:1000
In order to investigate the pathways responsible for the epithelial-mesenchymal transition in cells deficient for Cyclin A2, Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 9271) was used in western blot on mouse samples at 1:1000. Carcinogenesis (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; rat; fig 5
Cell Signaling Technology AKT1 antibody (Cell signaling, 4060) was used in western blot on rat samples (fig 5). Mar Drugs (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; 1:2000; fig  4
Cell Signaling Technology AKT1 antibody (Cell Signalling, 4060) was used in western blot on mouse samples at 1:2000 (fig  4). J Mol Cell Cardiol (2015) ncbi
rabbit polyclonal
  • western blot; human; fig 5
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on human samples (fig 5). Nat Commun (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; rat; 1:1000
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 4060) was used in western blot on rat samples at 1:1000. Exp Neurol (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; human; 1:1000; fig 3
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060S) was used in western blot on human samples at 1:1000 (fig 3). Cell Death Dis (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; human
In order to study the effect of using an ADAM17 inhibitory antibody, MEDI3622, in several EGFR-dependent tumor models, Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 4060) was used in western blot on human samples . Mol Cancer Ther (2015) ncbi
rabbit polyclonal
  • western blot; human; 1:1000; fig 4b
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 9271) was used in western blot on human samples at 1:1000 (fig 4b). Oncotarget (2015) ncbi
rabbit polyclonal
  • western blot; human
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 9271) was used in western blot on human samples . Mol Cancer Ther (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; human; 1:1500; fig 6
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060P) was used in western blot on human samples at 1:1500 (fig 6). Cancer Sci (2015) ncbi
rabbit polyclonal
  • immunocytochemistry; human
  • western blot; rat
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in immunocytochemistry on human samples and in western blot on rat samples . Toxicol Lett (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; fig 5
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on mouse samples (fig 5). J Neurotrauma (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; fig 1
Cell Signaling Technology AKT1 antibody (Cell signaling, 4060) was used in western blot on mouse samples (fig 1). FASEB J (2015) ncbi
rabbit polyclonal
  • western blot; human; fig 2
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 9271) was used in western blot on human samples (fig 2). Biochem Biophys Res Commun (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 4060) was used in western blot on mouse samples . Muscle Nerve (2016) ncbi
rabbit polyclonal
  • western blot; human; 1:500; fig 8
In order to analyze thyroid hormone receptor beta for oncogenic mutations, Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 9271) was used in western blot on human samples at 1:500 (fig 8). Oncotarget (2015) ncbi
rabbit polyclonal
  • western blot; mouse
In order to determine that PKB-mediated phosphorylation of AS160/TBC1D4 is one of the major PAS-binding signals in the heart in response to insulin, Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 9271) was used in western blot on mouse samples . PLoS ONE (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; human; 1:1000; fig 3
  • western blot; mouse; 1:1000; fig 5
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060S) was used in western blot on human samples at 1:1000 (fig 3) and in western blot on mouse samples at 1:1000 (fig 5). PLoS ONE (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; human
Cell Signaling Technology AKT1 antibody (Cell Signaling, D9E) was used in western blot on human samples . Cell Mol Life Sci (2015) ncbi
rabbit polyclonal
  • western blot; pig; fig 10
Cell Signaling Technology AKT1 antibody (Cell signaling, 9271S) was used in western blot on pig samples (fig 10). Am J Physiol Heart Circ Physiol (2015) ncbi
rabbit polyclonal
  • immunohistochemistry - paraffin section; human; fig s10
In order to characterize human solid salivary adenoid cystic carcinoma and high frequency of loss of PTEN expression as a targeted therapy, Cell Signaling Technology AKT1 antibody (Cell signaling, 9271) was used in immunohistochemistry - paraffin section on human samples (fig s10). Oncotarget (2015) ncbi
rabbit polyclonal
  • western blot; human
In order to investigate flotillin-1-mediated regulation of insulin-like growth factor-1 signaling, Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 9271) was used in western blot on human samples . J Cell Sci (2015) ncbi
rabbit monoclonal (D9E)
  • immunohistochemistry - paraffin section; human; loading ...; fig 5
  • western blot; human; loading ...; fig 2d
Cell Signaling Technology AKT1 antibody (Cell Signaling, D9E) was used in immunohistochemistry - paraffin section on human samples (fig 5) and in western blot on human samples (fig 2d). Am J Pathol (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; 1:1000
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 4060) was used in western blot on mouse samples at 1:1000. Int J Mol Sci (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; human; 1:2000; fig 3
In order to report a method of spatiotemporal control over cellular signaling, Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on human samples at 1:2000 (fig 3). Nat Commun (2015) ncbi
rabbit polyclonal
  • western blot; rat; loading ...; fig 7a
In order to compare the effect of over-expression of several inositol phosphate kinases on nerve growth factor-induced neurite outgrowth, Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271L) was used in western blot on rat samples (fig 7a). FEBS J (2015) ncbi
rabbit polyclonal
  • western blot; human
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology., 9271) was used in western blot on human samples . Cell Signal (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; rat; fig 1
In order to test if acute pharmacological activation of AKT induces cardioprotection, Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on rat samples (fig 1). J Transl Med (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; fig 7
In order to investigate the effects of nicotinamide adenine dinucleotide phosphate reduced oxidase 4 in liver tissues from patients with NASH and mice with steatohepatitis, Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on mouse samples (fig 7). Gastroenterology (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; human; 0.071 ug/ml; fig 4
In order to determine the contribution of ESR2 to medulloblastoma growth in vitro and in vivo, Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on human samples at 0.071 ug/ml (fig 4). Endocrinology (2015) ncbi
rabbit polyclonal
  • western blot; mouse
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on mouse samples . Breast Cancer Res (2015) ncbi
rabbit polyclonal
  • western blot; human
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on human samples . Mol Cell Endocrinol (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; fig f5
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on mouse samples (fig f5). Oncotarget (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; human
In order to identify and characterize a novel variant of MET that is expressed in high-grade gliomas, Cell Signaling Technology AKT1 antibody (CST, D9E) was used in western blot on human samples . Acta Neuropathol (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; human; fig s8
In order to identify proteins associated with EBNA3A, EBNA3B, and EBNA3C in lymphoblastoid cells, Cell Signaling Technology AKT1 antibody (Cell signaling, 4060) was used in western blot on human samples (fig s8). PLoS Pathog (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; human; 1:1000; fig 3b
In order to examine an immunoblot-analysis workflow for accuracy and precision, Cell Signaling Technology AKT1 antibody (Cell Signaling TECHNOLOGY, 4060) was used in western blot on human samples at 1:1000 (fig 3b). Sci Signal (2015) ncbi
rabbit monoclonal (D9E)
  • immunocytochemistry; mouse; fig 4
Cell Signaling Technology AKT1 antibody (Cell Signaling, D9E) was used in immunocytochemistry on mouse samples (fig 4). J Lipid Res (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; fig 1a
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, D9E) was used in western blot on mouse samples (fig 1a). Cancer Res (2015) ncbi
rabbit polyclonal
  • western blot; human; fig 8
Cell Signaling Technology AKT1 antibody (Cell Signalling, 9271) was used in western blot on human samples (fig 8). Oncotarget (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; fig 2
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on mouse samples (fig 2). Aging Cell (2015) ncbi
rabbit polyclonal
  • western blot; mouse; fig 5
Cell Signaling Technology AKT1 antibody (Cell signaling, 9271) was used in western blot on mouse samples (fig 5). Oncotarget (2015) ncbi
rabbit polyclonal
  • western blot; mouse; loading ...; fig 2f
In order to demonstrate that Hedgehog engages insulin-like growth signaling to activate the osteogenic program, Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on mouse samples (fig 2f). Proc Natl Acad Sci U S A (2015) ncbi
rabbit polyclonal
  • western blot; rat; fig 4
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 9271S) was used in western blot on rat samples (fig 4). Cell Physiol Biochem (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; 1:1000
In order to study the role of Notch-dependent erroneous cell cycle reentry in neurodegeneration, Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on mouse samples at 1:1000. Cell Death Differ (2015) ncbi
rabbit monoclonal (D9E)
  • immunohistochemistry - paraffin section; mouse; 1:150
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in immunohistochemistry - paraffin section on mouse samples at 1:150. Endocrinology (2015) ncbi
rabbit polyclonal
  • reverse phase protein lysate microarray; human; tbl s2
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 9271L) was used in reverse phase protein lysate microarray on human samples (tbl s2). Mol Syst Biol (2015) ncbi
rabbit monoclonal (D9E)
  • immunocytochemistry; human; 1:400
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 4060) was used in immunocytochemistry on human samples at 1:400. Mol Syst Biol (2015) ncbi
rabbit polyclonal
  • western blot; human; 1:1000; fig 4
In order to determine the contribution of low molecular weight protein tyrosine phosphatase to colorectal cancer, Cell Signaling Technology AKT1 antibody (Cell Signaling Tech, 9271) was used in western blot on human samples at 1:1000 (fig 4). Oncotarget (2015) ncbi
rabbit polyclonal
  • immunocytochemistry; human
  • western blot; human
In order to study Donohue syndrome in mesenchymal progenitor cells derived from human patients, Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in immunocytochemistry on human samples and in western blot on human samples . Endocrinology (2015) ncbi
rabbit polyclonal
  • western blot; mouse; fig 2
Cell Signaling Technology AKT1 antibody (Cell signaling, 9271) was used in western blot on mouse samples (fig 2). Mol Biol Cell (2015) ncbi
rabbit polyclonal
  • western blot; human; 1:500; tbl 3
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on human samples at 1:500 (tbl 3). PLoS ONE (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; 1:1000; fig 8
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on mouse samples at 1:1000 (fig 8). Development (2015) ncbi
rabbit monoclonal (D9E)
  • immunohistochemistry; mouse; 1:1000; fig 2
  • western blot; mouse; 1:1000; fig s2
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in immunohistochemistry on mouse samples at 1:1000 (fig 2) and in western blot on mouse samples at 1:1000 (fig s2). J Clin Invest (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; human; 1:2000
In order to test if NBDHEX and MC3181 have antitumor activity against melanoma cells resistant to vemurafenib, Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 4060) was used in western blot on human samples at 1:2000. Biochem Pharmacol (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; 1:1000
In order to characterize mice harboring a disrupted allele for the Lem2 gene, Cell Signaling Technology AKT1 antibody (CST, 4060) was used in western blot on mouse samples at 1:1000. PLoS ONE (2015) ncbi
rabbit polyclonal
  • western blot; human; fig s21
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 9271) was used in western blot on human samples (fig s21). PLoS ONE (2015) ncbi
rabbit polyclonal
  • western blot; mouse; loading ...; fig 7b
  • western blot; rat; fig 7a
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on mouse samples (fig 7b) and in western blot on rat samples (fig 7a). PLoS ONE (2015) ncbi
rabbit polyclonal
  • western blot; rat; 1:1000
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 9271) was used in western blot on rat samples at 1:1000. Neurobiol Dis (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; 1:1000; loading ...; fig 5c
  • western blot; human; 1:1000; loading ...; fig 3c
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 4060) was used in western blot on mouse samples at 1:1000 (fig 5c) and in western blot on human samples at 1:1000 (fig 3c). Mol Med Rep (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; human; 1:1000
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 4060) was used in western blot on human samples at 1:1000. PLoS ONE (2015) ncbi
rabbit polyclonal
  • western blot; human; loading ...; fig 2b
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on human samples (fig 2b). Oncotarget (2015) ncbi
rabbit polyclonal
  • western blot; human
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on human samples . Leukemia (2015) ncbi
rabbit monoclonal (D9E)
  • immunocytochemistry; mouse; 1:50; fig 6c
  • immunocytochemistry; human; 1:50; loading ...; fig 6d, 6e
  • western blot; human
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060 L) was used in immunocytochemistry on mouse samples at 1:50 (fig 6c), in immunocytochemistry on human samples at 1:50 (fig 6d, 6e) and in western blot on human samples . Sci Rep (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; fig 6a
In order to report that AMPK regulates protein phosphatase activity to control the of survival and function of CD8+ T cells, thus regulating immune surveillance of tumors, Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 4060) was used in western blot on mouse samples (fig 6a). Oncotarget (2015) ncbi
rabbit polyclonal
  • western blot; human; 1:1000
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 9271) was used in western blot on human samples at 1:1000. Mol Med Rep (2015) ncbi
rabbit polyclonal
  • western blot; human; fig 1
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on human samples (fig 1). Sci Signal (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; human; fig 5
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on human samples (fig 5). Cancer Cell (2015) ncbi
rabbit polyclonal
  • western blot; human; fig 5
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 9271) was used in western blot on human samples (fig 5). Sci Rep (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; 1:1000; loading ...; fig 1
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060L) was used in western blot on mouse samples at 1:1000 (fig 1). Nat Commun (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; human
In order to study the regulatory role of Arf1 in the Golgi and in hypersecretion in neuroendocrine cancer cells, Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, D9E) was used in western blot on human samples . J Cell Mol Med (2015) ncbi
rabbit polyclonal
  • western blot; human; 0.5 ug/ml; fig 4b
In order to examine the effect of amphiregulin on human hepatic stellate cells ex vivo and verify the contribution of amphiregulin to non-alcoholic fatty liver disease fibrogenesis in vivo, Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on human samples at 0.5 ug/ml (fig 4b). Sci Rep (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; human; 1:1000; loading ...; fig 4a
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060S) was used in western blot on human samples at 1:1000 (fig 4a). Mol Biol Cell (2015) ncbi
rabbit polyclonal
  • western blot; human; fig 2
Cell Signaling Technology AKT1 antibody (Cell signaling, 9271) was used in western blot on human samples (fig 2). Pigment Cell Melanoma Res (2015) ncbi
rabbit polyclonal
  • western blot; human; fig 1
Cell Signaling Technology AKT1 antibody (Cell signaling, 9271) was used in western blot on human samples (fig 1). Exp Mol Med (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; human; loading ...; fig 4a
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 4060) was used in western blot on human samples (fig 4a). Autophagy (2015) ncbi
rabbit polyclonal
  • western blot; human; 1:1000; fig 2c
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 9271) was used in western blot on human samples at 1:1000 (fig 2c). Sci Rep (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; human; loading ...; fig 4a,b
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on human samples (fig 4a,b). Onco Targets Ther (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; human; fig 7
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 4060) was used in western blot on human samples (fig 7). Tissue Eng Part A (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; human; fig 2
In order to study human breast cancer cell lines and how Heregulin-HER3-HER2 signaling promotes matrix metalloproteinase-dependent blood-brain-barrier transendothelial migration, Cell Signaling Technology AKT1 antibody (Cell signaling, D9E) was used in western blot on human samples (fig 2). Oncotarget (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; zebrafish ; fig 4a
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on zebrafish samples (fig 4a). FASEB J (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; human; 1:1000; loading ...; fig 1
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 4060) was used in western blot on human samples at 1:1000 (fig 1). PLoS ONE (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; 1:1000; fig s7a
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 4060) was used in western blot on mouse samples at 1:1000 (fig s7a). PLoS ONE (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; rat; 1:1000
Cell Signaling Technology AKT1 antibody (Cell Signaling, #4060) was used in western blot on rat samples at 1:1000. PLoS ONE (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; human; fig 2
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on human samples (fig 2). Cell Res (2015) ncbi
rabbit polyclonal
  • western blot; human; 1:500
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, #9271) was used in western blot on human samples at 1:500. Br J Pharmacol (2015) ncbi
rabbit polyclonal
  • western blot; human
In order to study bombesin receptor subtype-3 in patients with obesity and type 2 diabetes, Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 9271S) was used in western blot on human samples . Int J Mol Med (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; human
  • western blot; mouse
In order to show that FKBP12 and FKBP51 levels determine the responsiveness of a cell line or tissue to rapamycin, Cell Signaling Technology AKT1 antibody (Cell Signaling, #4060) was used in western blot on human samples and in western blot on mouse samples . Aging Cell (2015) ncbi
rabbit monoclonal (D9E)
  • immunohistochemistry - paraffin section; zebrafish ; 1:200
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in immunohistochemistry - paraffin section on zebrafish samples at 1:200. Mol Cancer (2015) ncbi
rabbit polyclonal
  • western blot; human
In order to study the effects of uPA and EGF in breast adenocarcinoma cell lines, Cell Signaling Technology AKT1 antibody (Cell Signalling, 9271S) was used in western blot on human samples . Mol Carcinog (2016) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse
  • western blot; human
In order to measure how RET activation by artemin is quantitatively coupled to key downstream effectors, Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 4060P) was used in western blot on mouse samples and in western blot on human samples . J Biol Chem (2015) ncbi
rabbit polyclonal
  • western blot; mouse
In order to show that MDSCs promote invasion of mammary carcinoma cells by increasing fibroblast migration, Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on mouse samples . PLoS ONE (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; loading ...; fig 4a
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on mouse samples (fig 4a). Am J Physiol Endocrinol Metab (2015) ncbi
rabbit polyclonal
  • western blot; mouse; 1:5000; fig 7
Cell Signaling Technology AKT1 antibody (Cell signaling, 9271) was used in western blot on mouse samples at 1:5000 (fig 7). Rejuvenation Res (2015) ncbi
rabbit monoclonal (D9E)
  • immunohistochemistry - paraffin section; mouse; 1:50
  • western blot; mouse; 1:1000
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in immunohistochemistry - paraffin section on mouse samples at 1:50 and in western blot on mouse samples at 1:1000. Nat Commun (2015) ncbi
rabbit monoclonal (D9E)
  • immunohistochemistry - paraffin section; rat
In order to study the effect of Pomegranate Fruit Extract (PFE) in a testosterone-induced benign prostatic hyperplasia model, Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in immunohistochemistry - paraffin section on rat samples . Prostate (2015) ncbi
rabbit polyclonal
  • western blot; human
Cell Signaling Technology AKT1 antibody (Cell Signaling Technologies, 9271) was used in western blot on human samples . J Biol Chem (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; human; 1:2000
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 4060) was used in western blot on human samples at 1:2000. Arthritis Rheumatol (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; human; 1:500; fig 1
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060L) was used in western blot on human samples at 1:500 (fig 1). PLoS ONE (2015) ncbi
rabbit polyclonal
  • western blot; mouse; loading ...; fig 3c
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on mouse samples (fig 3c). J Biol Chem (2015) ncbi
rabbit polyclonal
  • western blot; human
Cell Signaling Technology AKT1 antibody (Cell signalling, 9271) was used in western blot on human samples . Oncotarget (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; human
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 4060) was used in western blot on human samples . J Diabetes (2016) ncbi
rabbit polyclonal
  • western blot; mouse; 1:5000
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 9271) was used in western blot on mouse samples at 1:5000. Endocrinology (2015) ncbi
rabbit polyclonal
  • western blot; mouse
In order to elucidate the factors that mediate radiation-induced endothelial dysfunction, Cell Signaling Technology AKT1 antibody (Cst, 9271) was used in western blot on mouse samples . J Proteome Res (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; human; fig 1
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on human samples (fig 1). Breast Cancer Res (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; human; fig 9
  • western blot; mouse; fig 2
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on human samples (fig 9) and in western blot on mouse samples (fig 2). Mol Cell Biol (2015) ncbi
rabbit polyclonal
  • western blot; human; 1:1000; fig 7
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on human samples at 1:1000 (fig 7). Nat Cell Biol (2015) ncbi
rabbit monoclonal (D9E)
  • immunohistochemistry; human; 1:100
  • western blot; human; fig 1
In order to elucidate the tumor suppressor function of BTG3, Cell Signaling Technology AKT1 antibody (Cell Signaling Technologies, 4060) was used in immunohistochemistry on human samples at 1:100 and in western blot on human samples (fig 1). Cell Death Dis (2015) ncbi
rabbit polyclonal
  • western blot; mouse; 1:1000; fig s6
Cell Signaling Technology AKT1 antibody (Cell signaling, 9271) was used in western blot on mouse samples at 1:1000 (fig s6). Development (2015) ncbi
rabbit polyclonal
  • western blot; mouse
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on mouse samples . J Clin Invest (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; fig 7
In order to show that the PTEN-mTORC2 axis maintains T regulatory cell stability and coordinates their control of effector responses, Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, D9E) was used in western blot on mouse samples (fig 7). Nat Immunol (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; fig 2
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on mouse samples (fig 2). Cell (2015) ncbi
rabbit polyclonal
  • western blot; mouse; 1:1000; fig s12
In order to assess effects nuclear factor-erythroid 2-related factor 1 deficiency in beta-cells on beta-cell function and glucose homeostasis, Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 9271) was used in western blot on mouse samples at 1:1000 (fig s12). Antioxid Redox Signal (2015) ncbi
rabbit polyclonal
  • western blot; rat; loading ...; fig 5A
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on rat samples (fig 5A). J Appl Physiol (1985) (2015) ncbi
rabbit polyclonal
  • western blot; rat; fig 7c
Cell Signaling Technology AKT1 antibody (cell signaling, 9271) was used in western blot on rat samples (fig 7c). J Biol Chem (2015) ncbi
rabbit polyclonal
  • western blot; mouse; 1:1000; fig 3
In order to examine the neuroprotective effects and anti-inflammatory actions of berberine on traumatic brain injury, Cell Signaling Technology AKT1 antibody (Cell signaling, 9271) was used in western blot on mouse samples at 1:1000 (fig 3). PLoS ONE (2014) ncbi
rabbit polyclonal
  • western blot; mouse
In order to determine the effects of running on the neuronal structure and function of the hippocampus and amygdala in APP/PS1 transgenic mice, Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on mouse samples . Neurobiol Learn Mem (2015) ncbi
rabbit polyclonal
  • western blot; human; fig s3a
In order to develop methods to measure insulin transcytosis across individual, primary human adipose microvascular endothelial cells, Cell Signaling Technology AKT1 antibody (Cell signaling, 9271) was used in western blot on human samples (fig s3a). Mol Biol Cell (2015) ncbi
rabbit monoclonal (D9E)
  • immunocytochemistry; human; 1:100
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 4060) was used in immunocytochemistry on human samples at 1:100. Stem Cells (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; human; 1:1000
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 4060) was used in western blot on human samples at 1:1000. Oncotarget (2015) ncbi
rabbit monoclonal (D9E)
  • immunohistochemistry - frozen section; mouse; 1:200
  • western blot; mouse
Cell Signaling Technology AKT1 antibody (Cell Signaling Biotechnology, 4060) was used in immunohistochemistry - frozen section on mouse samples at 1:200 and in western blot on mouse samples . PLoS ONE (2014) ncbi
rabbit monoclonal (D9E)
  • immunohistochemistry - paraffin section; human; 1:250; fig 2
  • western blot; human; fig 2
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in immunohistochemistry - paraffin section on human samples at 1:250 (fig 2) and in western blot on human samples (fig 2). Br J Cancer (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; rat; 1:500; fig 12
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on rat samples at 1:500 (fig 12). J Appl Toxicol (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; human
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060P) was used in western blot on human samples . Biochim Biophys Acta (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; human
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 4060) was used in western blot on human samples . Int J Mol Sci (2014) ncbi
rabbit polyclonal
  • western blot; mouse
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on mouse samples . Diabetes (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; human
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on human samples . J Biol Chem (2015) ncbi
rabbit polyclonal
  • immunohistochemistry; human; 1:200; fig 5
  • western blot; human; 1:200; fig 4
In order to characterize human diabetic organ-cultured corneas by targeting miR-146a to treat delayed wound healing, Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in immunohistochemistry on human samples at 1:200 (fig 5) and in western blot on human samples at 1:200 (fig 4). PLoS ONE (2014) ncbi
rabbit polyclonal
  • western blot; human; 1:1000
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 9271) was used in western blot on human samples at 1:1000. Biochim Biophys Acta (2015) ncbi
rabbit polyclonal
  • western blot; mouse; loading ...; fig 3d
  • western blot; human; loading ...; fig 2g
In order to investigate the role of GNB1 and GNB2 in cancer cells., Cell Signaling Technology AKT1 antibody (Cell signaling, 9271) was used in western blot on mouse samples (fig 3d) and in western blot on human samples (fig 2g). Nat Med (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; loading ...; fig 3d
  • western blot; human; loading ...; fig 2g
In order to investigate the role of GNB1 and GNB2 in cancer cells., Cell Signaling Technology AKT1 antibody (Cell signaling, 4060) was used in western blot on mouse samples (fig 3d) and in western blot on human samples (fig 2g). Nat Med (2015) ncbi
rabbit monoclonal (D9E)
  • immunohistochemistry - paraffin section; mouse
  • western blot; mouse
In order to study the regulation of the canonical Wnt pathway and its effect on cardiac progenitor development, Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in immunohistochemistry - paraffin section on mouse samples and in western blot on mouse samples . Dev Biol (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; rat; 1:750
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on rat samples at 1:750. Ann Anat (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; 1:1000
In order to determine the effect of STA-2842 on liver size and cystic burden in Pkd-/- mice with established polycystic liver disease, Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060S) was used in western blot on mouse samples at 1:1000. PLoS ONE (2014) ncbi
rabbit monoclonal (D9E)
  • western blot; human; fig s4
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on human samples (fig s4). J Cell Sci (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; Rhesus monkey; fig s1
Cell Signaling Technology AKT1 antibody (Cell signaling, 4060) was used in western blot on Rhesus monkey samples (fig s1). FASEB J (2015) ncbi
rabbit polyclonal
  • western blot; mouse
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 9271) was used in western blot on mouse samples . J Proteomics (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; rat; 1:500
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060S) was used in western blot on rat samples at 1:500. Neuroscience (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060S) was used in western blot on mouse samples . PLoS ONE (2014) ncbi
rabbit monoclonal (D9E)
  • western blot; human; fig s1
Cell Signaling Technology AKT1 antibody (Cell Signaling Technologies, 4060) was used in western blot on human samples (fig s1). Mol Cell (2014) ncbi
rabbit polyclonal
  • western blot; rat
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 9271) was used in western blot on rat samples . Peptides (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse
In order to investigate the role of nephrin in beta-cell survival signaling, Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 40605) was used in western blot on mouse samples . Mol Cell Endocrinol (2015) ncbi
rabbit polyclonal
  • immunohistochemistry - frozen section; human; 1:50
In order to evaluate the therapeutical effects of gene therapy of limbal cells, Cell Signaling Technology AKT1 antibody (Cell signaling technology, 9271) was used in immunohistochemistry - frozen section on human samples at 1:50. Exp Eye Res (2014) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; fig 8a
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 4060S) was used in western blot on mouse samples (fig 8a). Free Radic Biol Med (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; human; fig 1
In order to study hepatocyte growth factor signaling and resistance to targeted cancer drugs, Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on human samples (fig 1). Cell Cycle (2014) ncbi
rabbit polyclonal
  • flow cytometry; human; loading ...; fig 6
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271S) was used in flow cytometry on human samples (fig 6). Invest New Drugs (2015) ncbi
rabbit polyclonal
  • western blot; mouse; 1:1000; fig 4
In order to study the effects and underlying mechanisms of TrkB activation on traumatic brain injury, Cell Signaling Technology AKT1 antibody (Cell signaling, 9271) was used in western blot on mouse samples at 1:1000 (fig 4). PLoS ONE (2014) ncbi
rabbit polyclonal
  • western blot; hamsters
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on hamsters samples . Front Cell Infect Microbiol (2014) ncbi
rabbit polyclonal
  • western blot; mouse; fig s7
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271s) was used in western blot on mouse samples (fig s7). Cell Death Dis (2014) ncbi
rabbit monoclonal (D9E)
  • immunohistochemistry - paraffin section; mouse; fig s4
In order to assess the effect of the C118S mutation of Kras on tumorigenesis, Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in immunohistochemistry - paraffin section on mouse samples (fig s4). Nat Commun (2014) ncbi
rabbit monoclonal (D9E)
  • western blot; rat
In order to test if Trp-His activates AMP-activated protein kinase to regulate the glucose transport system in skeletal muscle, Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 4060) was used in western blot on rat samples . FEBS Open Bio (2014) ncbi
rabbit polyclonal
  • western blot; rat; 1:500
In order to investigate the effects of estradiol and progesterone co-administered on ischemia, Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on rat samples at 1:500. Mol Neurobiol (2015) ncbi
rabbit polyclonal
  • western blot; human; fig 3
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on human samples (fig 3). Proteomics (2015) ncbi
rabbit polyclonal
  • western blot; mouse; 1:1000
In order to investigate the relationship between caveolin proteins and integrins in cardiac myocytes, Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on mouse samples at 1:1000. FASEB J (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; human; fig 5
Cell Signaling Technology AKT1 antibody (Cell Signaling Technologies, 4060) was used in western blot on human samples (fig 5). J Med Chem (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; human
In order to identify mechanisms by which metastatic gastroesophageal adenocarcinomas develop resistance to ERBB2 inhibition, Cell Signaling Technology AKT1 antibody (Cell Signaling Technologies, 4060) was used in western blot on human samples . PLoS ONE (2014) ncbi
rabbit monoclonal (D9E)
  • western blot; human; fig 4
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060S) was used in western blot on human samples (fig 4). Proc Natl Acad Sci U S A (2014) ncbi
rabbit monoclonal (D9E)
  • western blot; rat; 1:3000
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, D9E) was used in western blot on rat samples at 1:3000. Neurochem Res (2015) ncbi
rabbit polyclonal
  • western blot; rat; 1:500
In order to examine the role of the calcium- and integrin-activated proline-rich tyrosine kinase 2 in stretch-induced responses of the rat portal vein, Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 9271) was used in western blot on rat samples at 1:500. Physiol Rep (2014) ncbi
rabbit polyclonal
  • western blot; mouse; 1:1000; fig 4
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on mouse samples at 1:1000 (fig 4). elife (2014) ncbi
rabbit polyclonal
  • western blot; scFv; 1:1000
In order to study modulation of agomelatine by time dependent activation of Akt/GSK3 and MAPK/Erk1/2 cascades, Cell Signaling Technology AKT1 antibody (Cell Signalling Technology, 9271L) was used in western blot on scFv samples at 1:1000. BMC Neurosci (2014) ncbi
rabbit monoclonal (D9E)
  • western blot; rat
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on rat samples . PLoS ONE (2014) ncbi
rabbit polyclonal
  • western blot; human
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on human samples . J Mol Endocrinol (2014) ncbi
rabbit monoclonal (D9E)
  • western blot; human
In order to determine if inhibition of AKT signaling augments erlotinib activity and abrogates HGF-mediated resistance, Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 4060) was used in western blot on human samples . J Cancer Res Clin Oncol (2015) ncbi
rabbit monoclonal (D9E)
  • immunohistochemistry; human; 1:50
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, D9E) was used in immunohistochemistry on human samples at 1:50. Mol Cancer Ther (2014) ncbi
rabbit polyclonal
  • western blot; human
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 9271) was used in western blot on human samples . Mol Cancer Ther (2014) ncbi
rabbit polyclonal
  • western blot; human
In order to investigate the effect of bilirubin on HIF-1 expression in proximal tubular cells cultured in physiologically relevant oxygen concentration, Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on human samples . J Korean Med Sci (2014) ncbi
rabbit polyclonal
  • western blot; mouse
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on mouse samples . PLoS ONE (2014) ncbi
rabbit monoclonal (D9E)
  • western blot; human; fig 3, 4
In order to elucidate the mechanical and soluble mitogenic cues that promote the accumulation of tumor-associated fibroblasts in non-small cell lung cancer subtypes, Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 4060) was used in western blot on human samples (fig 3, 4). Mol Cancer Res (2015) ncbi
rabbit polyclonal
  • western blot; mouse; fig 2
Cell Signaling Technology AKT1 antibody (Cell signaling, 9271) was used in western blot on mouse samples (fig 2). Proc Natl Acad Sci U S A (2014) ncbi
rabbit polyclonal
  • western blot; human; 1:2000
In order to investigate the role of FOXO3a in Huntington disease, Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on human samples at 1:2000. J Biol Chem (2014) ncbi
rabbit polyclonal
  • western blot; rat; 1:1000
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on rat samples at 1:1000. Mol Psychiatry (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; rat; 12000
In order to investigate the effect of early postnatal overfeeding on insulin signaling in the ventral tegmental area, Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060S) was used in western blot on rat samples at 12000. Behav Brain Res (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on mouse samples . Genesis (2014) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; fig 1
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on mouse samples (fig 1). Cell (2014) ncbi
rabbit polyclonal
  • western blot; rat
In order to investigate the relationship between 5'-AMP-activated protein kinase and salicylate in skeletal muscle, Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 9271) was used in western blot on rat samples . Biochem Biophys Res Commun (2014) ncbi
rabbit polyclonal
  • western blot; human
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 9271) was used in western blot on human samples . Cell Signal (2014) ncbi
rabbit monoclonal (D9E)
  • western blot; human
In order to study the role of glycogen synthase kinase-3beta and protein phosphatase 2A in regulation of tau hyperphosphorylation, Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060s) was used in western blot on human samples . Neurobiol Aging (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on mouse samples . Physiol Rep (2014) ncbi
rabbit polyclonal
  • western blot; mouse
In order to study the role of prolactin and STAT5 during early prostate tumorigenesis, Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on mouse samples . Am J Pathol (2014) ncbi
rabbit polyclonal
  • immunocytochemistry; human
In order to study the mechanism of the activation of focal adhesion protein vinculin by mechanical stress, Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271S) was used in immunocytochemistry on human samples . Cancer Res (2014) ncbi
rabbit polyclonal
  • western blot; human
Cell Signaling Technology AKT1 antibody (Cell Signaling Technologies, 9271) was used in western blot on human samples . BMC Cancer (2014) ncbi
rabbit polyclonal
  • western blot; mouse; 1:1000
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 9271S) was used in western blot on mouse samples at 1:1000. J Neurosci (2014) ncbi
rabbit polyclonal
  • western blot; mouse; fig 2
In order to characterize how insulin resistance is induced and alteration of substrate utilization in vivo due to acute mTOR inhibition, Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 9271) was used in western blot on mouse samples (fig 2). Mol Metab (2014) ncbi
rabbit polyclonal
  • western blot; human; fig 4
In order to examine the mechanism of EML4-ALK rearrangement using a novel cell line, Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 9271) was used in western blot on human samples (fig 4). J Thorac Oncol (2014) ncbi
rabbit polyclonal
  • western blot; human
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on human samples . Proteomics (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; rat
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 4060) was used in western blot on rat samples . BMC Nephrol (2014) ncbi
rabbit polyclonal
  • immunohistochemistry; mouse; 1:1000; fig 3
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in immunohistochemistry on mouse samples at 1:1000 (fig 3). Mol Cancer Res (2015) ncbi
rabbit polyclonal
  • western blot; mouse
In order to study the effects of St John's Wart on adipocyte function in vivo, Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on mouse samples . Evid Based Complement Alternat Med (2014) ncbi
rabbit polyclonal
  • western blot; mouse; 1:1000; fig 4
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 9271) was used in western blot on mouse samples at 1:1000 (fig 4). Oncogene (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; fig 6
Cell Signaling Technology AKT1 antibody (Cell signaling, 4060) was used in western blot on mouse samples (fig 6). Nat Commun (2014) ncbi
rabbit polyclonal
  • western blot; mouse; 1:1000; fig 6
In order to study the role of Pax6 in the maintenance and differentiation of adult neural stem cells and in adult neurogenesis, Cell Signaling Technology AKT1 antibody (Cell Signalling, 9271) was used in western blot on mouse samples at 1:1000 (fig 6). Stem Cells Dev (2014) ncbi
rabbit polyclonal
  • western blot; human; fig 4
In order to study prostate cancer growth and the homeostatic regulation between tumor suppressor DAB2IP and ocogenic Skp2, Cell Signaling Technology AKT1 antibody (Cell signaling Technology, 9271) was used in western blot on human samples (fig 4). Oncotarget (2014) ncbi
rabbit monoclonal (D9E)
  • immunohistochemistry - frozen section; mouse; 1:1000
In order to study the effect of ketosis-inducing and non-inducing high fat diets on genes and proteins relevant to brain bioenergetic infrastructures, Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in immunohistochemistry - frozen section on mouse samples at 1:1000. J Bioenerg Biomembr (2015) ncbi
rabbit polyclonal
  • western blot; mouse
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 9271) was used in western blot on mouse samples . Molecules (2014) ncbi
rabbit polyclonal
  • western blot; human
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 9271) was used in western blot on human samples . J Leukoc Biol (2014) ncbi
rabbit polyclonal
  • western blot; mouse
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on mouse samples . Mol Cell Biol (2014) ncbi
rabbit monoclonal (D9E)
  • western blot; human; loading ...; fig 6a
Cell Signaling Technology AKT1 antibody (cell signalling, 4060) was used in western blot on human samples (fig 6a). Oncotarget (2014) ncbi
rabbit polyclonal
  • western blot; human
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 9271) was used in western blot on human samples . Biochem Biophys Res Commun (2014) ncbi
rabbit polyclonal
  • western blot; mouse; 1:1000
In order to investigate the involvement of matrix metalloproteinase 9 in the phenotype of fragile X syndrome, Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 9271) was used in western blot on mouse samples at 1:1000. J Neurosci (2014) ncbi
rabbit polyclonal
  • western blot; rat
  • western blot; mouse
In order to investigate the mechanism for the neuroprotective effect of Klotho, Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on rat samples and in western blot on mouse samples . J Biol Chem (2014) ncbi
rabbit polyclonal
  • western blot; mouse; 1:300; fig 2
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on mouse samples at 1:300 (fig 2). Skelet Muscle (2014) ncbi
rabbit monoclonal (D9E)
  • western blot; human; fig 2
Cell Signaling Technology AKT1 antibody (Cell Signaling Tech, 4060) was used in western blot on human samples (fig 2). Oncogene (2015) ncbi
rabbit polyclonal
  • western blot; mouse; 1:1000
Cell Signaling Technology AKT1 antibody (Cell Signalling, 9271) was used in western blot on mouse samples at 1:1000. PLoS ONE (2014) ncbi
rabbit monoclonal (D9E)
  • western blot; human
In order to study mechanisms underlying resistance to MET monoclonal antibodies and chemical tyrosine kinase inhibitors, Cell Signaling Technology AKT1 antibody (cell Signaling, 4060) was used in western blot on human samples . Mol Oncol (2014) ncbi
rabbit polyclonal
  • western blot; mouse
In order to study the mechanisms of craniosynostosis and the effects of purified soluble FGFR2 harboring the S252W mutation on the calvarial sutures in Apert syndrome mice, Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 9271) was used in western blot on mouse samples . PLoS ONE (2014) ncbi
rabbit polyclonal
  • western blot; human; 1:1000; fig 7
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 9271) was used in western blot on human samples at 1:1000 (fig 7). Oncotarget (2014) ncbi
rabbit monoclonal (D9E)
  • western blot; human; fig s3b
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on human samples (fig s3b). Proc Natl Acad Sci U S A (2014) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; 1:1000
In order to determine how intensive exercise affects brain bioenergetics, inflammation, and neurogenesis-relevant parameters, Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 4060) was used in western blot on mouse samples at 1:1000. Neurobiol Aging (2014) ncbi
rabbit polyclonal
  • western blot; human
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 9271) was used in western blot on human samples . PLoS ONE (2014) ncbi
rabbit monoclonal (D9E)
  • western blot; human; fig 5
Cell Signaling Technology AKT1 antibody (Cell Signaling Technologies, 4060) was used in western blot on human samples (fig 5). PLoS ONE (2014) ncbi
rabbit polyclonal
  • western blot; mouse; fig 3a
In order to elucidate how EglN2 regulates FOXO3a degradation, Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on mouse samples (fig 3a). Genes Dev (2014) ncbi
rabbit monoclonal (D9E)
  • western blot; human
Cell Signaling Technology AKT1 antibody (Cell Signaling technology, 4060) was used in western blot on human samples . PLoS ONE (2014) ncbi
rabbit polyclonal
  • western blot; human; 1:4000
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271S) was used in western blot on human samples at 1:4000. J Biol Chem (2014) ncbi
rabbit polyclonal
  • western blot; human; fig 5
Cell Signaling Technology AKT1 antibody (Cell signaling, 9271) was used in western blot on human samples (fig 5). J Biol Chem (2014) ncbi
rabbit polyclonal
  • western blot; human; 1:1000
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 9271) was used in western blot on human samples at 1:1000. Tissue Eng Part A (2014) ncbi
rabbit monoclonal (D9E)
  • flow cytometry; human; 1:100
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 4060) was used in flow cytometry on human samples at 1:100. Tissue Eng Part A (2014) ncbi
rabbit polyclonal
  • western blot; mouse
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on mouse samples . Pharmacol Res (2014) ncbi
rabbit monoclonal (D9E)
  • western blot; human; 1:1000
Cell Signaling Technology AKT1 antibody (Cell Signalling Technology, 4060) was used in western blot on human samples at 1:1000. Cell Signal (2014) ncbi
rabbit polyclonal
  • western blot; mouse; 1:1000
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on mouse samples at 1:1000. Development (2014) ncbi
rabbit polyclonal
  • western blot; human; 1:1000; fig 3
In order to characterize a monoclonal anti-human c-kit antibody for inhibiting tumor growth, Cell Signaling Technology AKT1 antibody (Cell signaling, 9271) was used in western blot on human samples at 1:1000 (fig 3). Cancer Biol Ther (2014) ncbi
rabbit polyclonal
  • western blot; human; fig 2
Cell Signaling Technology AKT1 antibody (Cell Signaling Tech, 9271) was used in western blot on human samples (fig 2). Oncogene (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; human
In order to study mechanism of resistance to the FGFR inhibitor BGJ398 and the FGFR inhibitor ponatinib, Cell Signaling Technology AKT1 antibody (cell signaling, 4060S) was used in western blot on human samples . Oncogene (2015) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; 1:1000
Cell Signaling Technology AKT1 antibody (Cell signaling, 4060P) was used in western blot on mouse samples at 1:1000. PLoS ONE (2014) ncbi
rabbit polyclonal
  • western blot; human; 1:1000
Cell Signaling Technology AKT1 antibody (Cell Signaling Technologies, 9271) was used in western blot on human samples at 1:1000. BMC Cancer (2014) ncbi
rabbit polyclonal
  • western blot; gilthead bream; 1:200
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 9271) was used in western blot on gilthead bream samples at 1:200. Gen Comp Endocrinol (2014) ncbi
rabbit monoclonal (D9E)
  • western blot; human
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 4060) was used in western blot on human samples . Cell Signal (2014) ncbi
rabbit monoclonal (D9E)
  • immunohistochemistry - paraffin section; mouse
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 4060) was used in immunohistochemistry - paraffin section on mouse samples . PLoS Genet (2014) ncbi
rabbit monoclonal (D9E)
  • western blot; human; loading ...; fig 1a
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on human samples (fig 1a). PLoS ONE (2014) ncbi
rabbit polyclonal
  • western blot; mouse; 1:1000
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on mouse samples at 1:1000. Int J Biochem Cell Biol (2014) ncbi
rabbit monoclonal (D9E)
  • western blot; human; fig 4
Cell Signaling Technology AKT1 antibody (Cell signaling, 4060S) was used in western blot on human samples (fig 4). Nature (2014) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, D9E) was used in western blot on mouse samples . J Immunol (2014) ncbi
rabbit monoclonal (D9E)
  • western blot; rabbit; 1:2,000
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 4060S) was used in western blot on rabbit samples at 1:2,000. Stem Cells Dev (2014) ncbi
rabbit polyclonal
  • western blot; mouse
In order to demonstrate a novel role for Poldip2 in regulating the cell cycle, Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271S) was used in western blot on mouse samples . PLoS ONE (2014) ncbi
rabbit polyclonal
  • western blot; rat; 1:1000
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271S) was used in western blot on rat samples at 1:1000. PLoS ONE (2014) ncbi
rabbit polyclonal
  • western blot; human
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on human samples . Int J Oncol (2014) ncbi
rabbit polyclonal
  • western blot; human
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 9271) was used in western blot on human samples . Biochem J (2014) ncbi
rabbit monoclonal (D9E)
  • western blot; rat; 1:2000
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 4060) was used in western blot on rat samples at 1:2000. Exp Gerontol (2014) ncbi
rabbit monoclonal (D9E)
  • western blot; human
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 4060) was used in western blot on human samples . Eur J Immunol (2014) ncbi
rabbit monoclonal (D9E)
  • western blot; rat
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on rat samples . Toxicol Pathol (2014) ncbi
rabbit polyclonal
  • western blot; rat
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 9271) was used in western blot on rat samples . PLoS ONE (2014) ncbi
rabbit polyclonal
  • western blot; rat
In order to examine the role of GPR30 in 17beta-estradiol-mediated neuroprotection after an ischemic injury in an organotypic hippocampal slice culture model, Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on rat samples . Brain Res (2014) ncbi
rabbit monoclonal (D9E)
  • immunohistochemistry - paraffin section; human; 1:50
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, D9E) was used in immunohistochemistry - paraffin section on human samples at 1:50. Clin Cancer Res (2014) ncbi
rabbit polyclonal
  • western blot; human
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on human samples . Oncotarget (2014) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; 1:1000
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 4060) was used in western blot on mouse samples at 1:1000. J Neurosci (2014) ncbi
rabbit polyclonal
  • western blot; mouse
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271S) was used in western blot on mouse samples . Am J Physiol Renal Physiol (2014) ncbi
rabbit monoclonal (D9E)
  • western blot; human; 1:1000
In order to establish a primary culture of Oct3/4(+)/Nanog(+) lung cancer stem cells fed with CD90(+) cancer-associated fibroblasts to study stem cells in the tumor microenvironment, Cell Signaling Technology AKT1 antibody (cst, D9E) was used in western blot on human samples at 1:1000. Nat Commun (2014) ncbi
rabbit polyclonal
  • western blot; rat
Cell Signaling Technology AKT1 antibody (Cell Signaling Technologies, 9271) was used in western blot on rat samples . PLoS ONE (2014) ncbi
rabbit monoclonal (D9E)
  • western blot; human
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 4060) was used in western blot on human samples . Oncotarget (2014) ncbi
rabbit polyclonal
  • western blot; human; fig 4a, b
In order to suggest that Akt activation by ERBB3/HER2 limits the effectiveness of EGFR inhibition, Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 9271) was used in western blot on human samples (fig 4a, b). Mol Cancer Ther (2014) ncbi
rabbit polyclonal
  • western blot; human; 1:1000; fig 1
In order to study the anti-tumor effects of a pan class I PI3 kinase/mTOR inhibitor in cells with a genetically diverse range of PI3 kinase pathway modifications, Cell Signaling Technology AKT1 antibody (CST, 9271) was used in western blot on human samples at 1:1000 (fig 1). Mol Cancer Ther (2014) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse
Cell Signaling Technology AKT1 antibody (Cell Signaling Technologies, 4060) was used in western blot on mouse samples . PLoS ONE (2014) ncbi
rabbit polyclonal
  • western blot; human; 1:1000
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on human samples at 1:1000. Int J Cancer (2014) ncbi
rabbit polyclonal
  • western blot; human
In order to study the preventive effects of pelargonidin toward atherosclerosis mechanistically, Cell Signaling Technology AKT1 antibody (Cell Signaling Biotechnology, 9271S) was used in western blot on human samples . Biochem Pharmacol (2014) ncbi
rabbit polyclonal
  • western blot; human; 1:1000
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 9271) was used in western blot on human samples at 1:1000. Nanomedicine (2014) ncbi
rabbit polyclonal
  • western blot; rat
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 9271) was used in western blot on rat samples . Am J Physiol Heart Circ Physiol (2014) ncbi
rabbit monoclonal (D9E)
  • immunohistochemistry - paraffin section; human
In order to investigate the expression and activity of receptor tyrosine kinases, MAP kinase, AKT, or Hippo pathways in human schwannomas, Cell Signaling Technology AKT1 antibody (CST, 4060) was used in immunohistochemistry - paraffin section on human samples . Neuro Oncol (2014) ncbi
rabbit monoclonal (D9E)
  • immunohistochemistry; mouse
  • western blot; mouse
In order to study the role of Cdk1 signaling in the mechanism by which filamin B modulates the proliferation and differentiation of chondrocytes, Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in immunohistochemistry on mouse samples and in western blot on mouse samples . PLoS ONE (2014) ncbi
rabbit polyclonal
  • western blot; human
Cell Signaling Technology AKT1 antibody (Cell signaling, 9271) was used in western blot on human samples . PLoS ONE (2014) ncbi
rabbit monoclonal (D9E)
  • western blot; human
Cell Signaling Technology AKT1 antibody (Cell Signaling Technologies, 4060) was used in western blot on human samples . PLoS ONE (2014) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 4060) was used in western blot on mouse samples . J Biol Chem (2014) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse
In order to study the phosphorylation of Cx43 and its effect on gap junction turnover in vivo, Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on mouse samples . FEBS Lett (2014) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 4060) was used in western blot on mouse samples . Int J Dev Neurosci (2014) ncbi
rabbit monoclonal (D9E)
  • western blot; rat; 1:1000
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 4060) was used in western blot on rat samples at 1:1000. J Nutr Biochem (2014) ncbi
rabbit polyclonal
  • western blot; mouse
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on mouse samples . J Biol Chem (2014) ncbi
rabbit polyclonal
  • western blot; human
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on human samples . Cell Death Dis (2014) ncbi
rabbit polyclonal
  • western blot; human; 1:2000
In order to identify an epigenetic mechanism of crosstalk between STAT3 and NF-kappaB that regulates constitutive STAT3 activation in oncogenesis, Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 9271) was used in western blot on human samples at 1:2000. Sci Signal (2014) ncbi
rabbit polyclonal
  • western blot; dog
Cell Signaling Technology AKT1 antibody (Cell Signalling, 9271) was used in western blot on dog samples . PLoS ONE (2014) ncbi
rabbit monoclonal (D9E)
  • western blot; human; 1:1000; fig 7
In order to demonstrate a tumor-suppressive role for SLAP in colorectal cancer, Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 4060) was used in western blot on human samples at 1:1000 (fig 7). Nat Commun (2014) ncbi
rabbit polyclonal
  • immunoprecipitation; human
  • western blot; human
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in immunoprecipitation on human samples and in western blot on human samples . Carcinogenesis (2014) ncbi
rabbit polyclonal
  • western blot; mouse; 1:1000; fig 3, 5
In order to test if MuRF1 inhibits insulin-like growth factor-I-mediated physiological cardiomyocyte growth, Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 9271) was used in western blot on mouse samples at 1:1000 (fig 3, 5). Am J Physiol Endocrinol Metab (2014) ncbi
rabbit monoclonal (D9E)
  • immunohistochemistry; human; 1:2000
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 4060) was used in immunohistochemistry on human samples at 1:2000. Scand J Med Sci Sports (2015) ncbi
rabbit polyclonal
  • western blot; human; 1:500
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on human samples at 1:500. Stem Cell Rev (2014) ncbi
rabbit polyclonal
  • western blot; mouse; fig 5, 7
In order to test if loss of Vcl and ZO-1 interactions destabilizes gap junctions in cardiomyocytes, Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on mouse samples (fig 5, 7). J Cell Sci (2014) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; 1:1000
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060S) was used in western blot on mouse samples at 1:1000. J Biol Chem (2014) ncbi
rabbit monoclonal (D9E)
  • immunohistochemistry; mouse; 1:50
In order to confirm the role of PTEN signaling in Olig2 expressing neural progenitor cells and oligodendrocytes, Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, D9E) was used in immunohistochemistry on mouse samples at 1:50. Stem Cells (2014) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; 1:2500
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 4060) was used in western blot on mouse samples at 1:2500. Am J Physiol Gastrointest Liver Physiol (2014) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse
In order to study the beneficial effects of increasing the O-GlucNAcylation of brain proteins on the survival and breathing of aged tau P301L transgenic mice, Cell Signaling Technology AKT1 antibody (Cell Signaling, D9E) was used in western blot on mouse samples . PLoS ONE (2013) ncbi
rabbit monoclonal (D9E)
  • flow cytometry; mouse
Cell Signaling Technology AKT1 antibody (Cell Signaling, D9E) was used in flow cytometry on mouse samples . Eur J Immunol (2014) ncbi
rabbit polyclonal
  • western blot; human
In order to study treatment resistance mechanisms in triple-negative breast cancers, Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on human samples . Cancer Discov (2014) ncbi
rabbit monoclonal (D9E)
  • western blot; human
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on human samples . J Biol Chem (2014) ncbi
rabbit polyclonal
  • proximity ligation assay; human; fig 3
  • western blot; human; fig 1
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 9271) was used in proximity ligation assay on human samples (fig 3) and in western blot on human samples (fig 1). Tumour Biol (2014) ncbi
rabbit monoclonal (D9E)
  • flow cytometry; human; loading ...; fig 5a
Cell Signaling Technology AKT1 antibody (Cell Signaling, D9E) was used in flow cytometry on human samples (fig 5a). J Immunol (2014) ncbi
rabbit polyclonal
  • western blot; mouse; fig 3
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on mouse samples (fig 3). Autophagy (2014) ncbi
rabbit monoclonal (D9E)
  • western blot; rat; 1:1000
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, D9E) was used in western blot on rat samples at 1:1000. Neuroscience (2014) ncbi
rabbit monoclonal (D9E)
  • western blot; rat
In order to study the distinct roles of different calpain isoforms in synaptic neuroprotection and extrasynaptic neurodegeneration mediated by the NMDA receptor, Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 4060) was used in western blot on rat samples . J Neurosci (2013) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; 1:1000
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 4060) was used in western blot on mouse samples at 1:1000. Biochim Biophys Acta (2014) ncbi
rabbit polyclonal
  • western blot; human
In order to investigate the effect of IL-33 on the expression of ADAMTS-1, -4 and -5 in human macrophages and atherosclerotic lesions, Cell Signaling Technology AKT1 antibody (Cell Signaling Technologies, 9271) was used in western blot on human samples . Int J Biochem Cell Biol (2014) ncbi
rabbit polyclonal
  • western blot; mouse; fig 4
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 9271) was used in western blot on mouse samples (fig 4). Biochemistry (2013) ncbi
rabbit monoclonal (D9E)
  • immunohistochemistry - free floating section; mouse; 1:200
In order to describe the synaptic changes in neurons lacking PTEN, Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in immunohistochemistry - free floating section on mouse samples at 1:200. J Comp Neurol (2014) ncbi
rabbit polyclonal
  • western blot; human
In order to evaluate a novel insulin/IGF signaling pathway inhibitor for its protective effect on age-onset, neurodegeneration-linked proteotoxicity, Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 9271) was used in western blot on human samples . Aging Cell (2014) ncbi
rabbit monoclonal (D9E)
  • immunohistochemistry; human
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in immunohistochemistry on human samples . Mol Cancer Ther (2014) ncbi
rabbit polyclonal
  • western blot; human
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on human samples . Mol Cancer Ther (2014) ncbi
rabbit polyclonal
  • western blot; human
Cell Signaling Technology AKT1 antibody (Cell Signalling Technology, 9271) was used in western blot on human samples . J Physiol (2014) ncbi
rabbit monoclonal (D9E)
  • western blot; rat; 1:1000
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on rat samples at 1:1000. Exp Cell Res (2014) ncbi
rabbit monoclonal (D9E)
  • western blot; African green monkey
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on African green monkey samples . J Cell Sci (2014) ncbi
rabbit polyclonal
  • western blot; human; 1:500; fig 6a
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on human samples at 1:500 (fig 6a). J Biol Chem (2013) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; 1:10000
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on mouse samples at 1:10000. Diabetes (2014) ncbi
rabbit polyclonal
  • western blot; mouse; 1:5000
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on mouse samples at 1:5000. Diabetes (2014) ncbi
rabbit polyclonal
  • western blot; mouse; 1:500
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 9271) was used in western blot on mouse samples at 1:500. Nat Med (2013) ncbi
rabbit polyclonal
  • western blot; mouse; 1:1000
In order to investigate the role of microglial derived tumor necrosis factor alpha in neuronal cell cycle progression, Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on mouse samples at 1:1000. Neurobiol Dis (2014) ncbi
rabbit polyclonal
  • immunocytochemistry; mouse; fig 3
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in immunocytochemistry on mouse samples (fig 3). BMC Biol (2013) ncbi
rabbit polyclonal
  • western blot; human; 1:1000
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 9271) was used in western blot on human samples at 1:1000. Phytother Res (2014) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 4060) was used in western blot on mouse samples . Am J Pathol (2013) ncbi
rabbit monoclonal (D9E)
  • western blot; human; 1:2000
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 4060) was used in western blot on human samples at 1:2000. FASEB J (2014) ncbi
rabbit polyclonal
  • immunohistochemistry; human
  • western blot; human; fig 4
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in immunohistochemistry on human samples and in western blot on human samples (fig 4). Cancer Res (2013) ncbi
rabbit monoclonal (D9E)
  • western blot; human; fig 1g
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 4060) was used in western blot on human samples (fig 1g). PLoS ONE (2013) ncbi
rabbit monoclonal (D9E)
  • immunohistochemistry - paraffin section; human; 1:50
  • western blot; human
In order to evaluate the effect of NVP-BEZ235 and MEK inhibitor ADZ4266 on murine mismatch repair deficient tumors, Cell Signaling Technology AKT1 antibody (Cell Signaling Technologies, 4060) was used in immunohistochemistry - paraffin section on human samples at 1:50 and in western blot on human samples . PLoS ONE (2013) ncbi
rabbit polyclonal
  • western blot; human; loading ...; fig 4a
Cell Signaling Technology AKT1 antibody (cell signalling, 9271) was used in western blot on human samples (fig 4a). Int J Cancer (2014) ncbi
rabbit polyclonal
  • western blot; mouse; 1:1000
In order to investigate the role of Tbc1d1 in insulin- and AICAR-stimulated glucose uptake in skeletal muscle, Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on mouse samples at 1:1000. Endocrinology (2013) ncbi
rabbit polyclonal
  • western blot; mouse; 1:1000
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 9271s) was used in western blot on mouse samples at 1:1000. Food Chem (2013) ncbi
rabbit polyclonal
  • western blot; human
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 9271L) was used in western blot on human samples . PLoS ONE (2013) ncbi
rabbit monoclonal (D9E)
  • western blot; human
Cell Signaling Technology AKT1 antibody (Cell Signaling Technologies, 4060) was used in western blot on human samples . PLoS ONE (2013) ncbi
rabbit polyclonal
  • western blot; mouse
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on mouse samples . Diabetes (2013) ncbi
rabbit polyclonal
  • western blot; mouse; fig 5
In order to study the protective effects against cardiac steatosis and dilated cardiomyopathy of specifically overexpressing triglyceride lipase in cardiomyocytes in a murine model of diet-induced obesity, Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on mouse samples (fig 5). Int J Obes (Lond) (2014) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; fig 2b
In order to study the cardiac effects of neuregulin in cMLCK knockout mice, Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 4060) was used in western blot on mouse samples (fig 2b). PLoS ONE (2013) ncbi
rabbit monoclonal (D9E)
  • western blot; human; fig 4
In order to study targeting sEcad for treatment of breast cancer, Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on human samples (fig 4). Mol Carcinog (2014) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; 1:1,000
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on mouse samples at 1:1,000. J Comp Neurol (2013) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; 1:1000
In order to investigate the role of insulin receptor substrate 2 in testicular development, Cell Signaling Technology AKT1 antibody (Cell Signalling, 4060) was used in western blot on mouse samples at 1:1000. PLoS ONE (2013) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse
  • western blot; human
In order to study the role of the sphingosine-1-phosphate in the mechanism by which acid ceramidase promotes oncogenic Akt signaling, Cell Signaling Technology AKT1 antibody (Cell Signaling Technologie, 4060) was used in western blot on mouse samples and in western blot on human samples . Oncogenesis (2013) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse
In order to investigate the role of hepatocyte growth factor receptor, c-met in renoprotection, Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on mouse samples . Kidney Int (2013) ncbi
rabbit polyclonal
  • western blot; human
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 9271) was used in western blot on human samples . PLoS ONE (2013) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse
Cell Signaling Technology AKT1 antibody (Cell Signaling, D9E) was used in western blot on mouse samples . Mol Cancer Ther (2013) ncbi
rabbit polyclonal
  • western blot; rat; 1:200
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on rat samples at 1:200. Biochem J (2013) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse
  • western blot; human
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on mouse samples and in western blot on human samples . Invest Ophthalmol Vis Sci (2013) ncbi
rabbit polyclonal
  • western blot; rat
Cell Signaling Technology AKT1 antibody (CST, 9271) was used in western blot on rat samples . Diabetes (2013) ncbi
rabbit polyclonal
  • western blot; mouse; 1:2000
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on mouse samples at 1:2000. Oncogene (2014) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; 1:1000
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 4060) was used in western blot on mouse samples at 1:1000. Brain Res (2013) ncbi
rabbit monoclonal (D9E)
  • western blot; human; 1:1000; fig 5
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on human samples at 1:1000 (fig 5). Cell Death Dis (2013) ncbi
rabbit polyclonal
  • western blot; human
Cell Signaling Technology AKT1 antibody (Cell signal, 9271) was used in western blot on human samples . J Cell Mol Med (2013) ncbi
rabbit polyclonal
  • western blot; human
In order to examine the relation of GATA3 and TGF beta in breast cancer cells, Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 9271) was used in western blot on human samples . PLoS ONE (2013) ncbi
rabbit polyclonal
  • western blot; mouse; 1:2000
In order to identify the role of carboxyl terminus of Hsp70-interacting protein in cardiac hypertrophy and attenuate autophagy during exercise, Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on mouse samples at 1:2000. Cell Biochem Funct (2013) ncbi
rabbit polyclonal
  • western blot; human; fig 4
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on human samples (fig 4). J Biol Chem (2013) ncbi
rabbit monoclonal (D9E)
  • western blot; human; fig 2
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on human samples (fig 2). Genes Dev (2013) ncbi
rabbit polyclonal
  • western blot; human; fig s3d
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on human samples (fig s3d). J Physiol (2013) ncbi
rabbit monoclonal (D9E)
  • western blot; human; fig 5
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 4060S) was used in western blot on human samples (fig 5). Biochem J (2013) ncbi
rabbit polyclonal
  • western blot; human
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on human samples . J Physiol (2013) ncbi
rabbit monoclonal (D9E)
  • immunohistochemistry - frozen section; mouse; 1:50
  • western blot; mouse; 1:500
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 4060) was used in immunohistochemistry - frozen section on mouse samples at 1:50 and in western blot on mouse samples at 1:500. PLoS ONE (2013) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 4060) was used in western blot on mouse samples . PLoS ONE (2013) ncbi
rabbit polyclonal
  • western blot; human
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on human samples . Cell Cycle (2013) ncbi
rabbit monoclonal (D9E)
  • western blot; human; 1:2,000
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on human samples at 1:2,000. PLoS ONE (2012) ncbi
rabbit polyclonal
  • western blot; mouse; 1:1000; fig 6a
In order to study the development of fatal cardiac hypertrophy and arrrhythmia in mice overexpressing miRNA-17-92 in heart and smooth muscle, Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 9271) was used in western blot on mouse samples at 1:1000 (fig 6a). FASEB J (2013) ncbi
rabbit polyclonal
  • immunocytochemistry; human
  • western blot; human
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in immunocytochemistry on human samples and in western blot on human samples . Cell Cycle (2013) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse; loading ...; fig 4d
Cell Signaling Technology AKT1 antibody (Cell signaling, 4060) was used in western blot on mouse samples (fig 4d). Proc Natl Acad Sci U S A (2012) ncbi
rabbit monoclonal (D9E)
  • immunocytochemistry; human
  • western blot; human; fig 2
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in immunocytochemistry on human samples and in western blot on human samples (fig 2). J Biol Chem (2013) ncbi
rabbit polyclonal
  • western blot; human
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271s) was used in western blot on human samples . J Biol Chem (2013) ncbi
rabbit monoclonal (D9E)
  • western blot; human; 1:1000
Cell Signaling Technology AKT1 antibody (Cell Signaling, 4060) was used in western blot on human samples at 1:1000. FEBS Lett (2013) ncbi
rabbit polyclonal
  • western blot; hamsters
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 9271) was used in western blot on hamsters samples . Mol Cell Biol (2013) ncbi
rabbit polyclonal
  • immunocytochemistry; dog
  • western blot; dog
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 9271) was used in immunocytochemistry on dog samples and in western blot on dog samples . J Biol Chem (2012) ncbi
rabbit polyclonal
  • western blot; mouse
In order to study the role of AS160 in the insulin responses in multiple tissues, Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 9271) was used in western blot on mouse samples . Biochem J (2013) ncbi
rabbit polyclonal
  • western blot; rat
Cell Signaling Technology AKT1 antibody (Cell Signalling, 9271) was used in western blot on rat samples . J Appl Physiol (1985) (2012) ncbi
rabbit polyclonal
  • western blot; human; 1:1000
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on human samples at 1:1000. Oncogene (2013) ncbi
rabbit polyclonal
  • western blot; human; fig 1
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 9271) was used in western blot on human samples (fig 1). PLoS ONE (2012) ncbi
rabbit polyclonal
  • western blot; mouse
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 9271S) was used in western blot on mouse samples . Eur J Immunol (2011) ncbi
rabbit monoclonal (D9E)
  • western blot; mouse
In order to investigate how plakoglobin affects beta-catenin activity in the heart, Cell Signaling Technology AKT1 antibody (Cell Signaling, D9E) was used in western blot on mouse samples . Mol Cell Biol (2011) ncbi
rabbit polyclonal
  • western blot; human; fig 5
Cell Signaling Technology AKT1 antibody (Cell Signaling, 9271) was used in western blot on human samples (fig 5). Leukemia (2011) ncbi
rabbit polyclonal
  • western blot; human; fig 7a
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 9271) was used in western blot on human samples (fig 7a). Cell Death Differ (2010) ncbi
rabbit polyclonal
  • western blot; human
Cell Signaling Technology AKT1 antibody (Cell Signaling Technology, 9271) was used in western blot on human samples . J Endocrinol (2010) ncbi
EMD Millipore
rabbit monoclonal (SK703)
  • western blot; human; fig 2
EMD Millipore AKT1 antibody (EMD-Millipore, 04-736) was used in western blot on human samples (fig 2). BMC Res Notes (2016) ncbi
rabbit monoclonal (NL50)
  • western blot; rat; 1:1000; loading ...; fig 7a
EMD Millipore AKT1 antibody (Millipore, 04-802) was used in western blot on rat samples at 1:1000 (fig 7a). Mol Med Rep (2016) ncbi
rabbit monoclonal (NL50)
  • western blot; human; fig 5
In order to study how acute environmental hypoxia regulates blood glucose and downstream intramuscular insulin signaling after humans eat a meal, EMD Millipore AKT1 antibody (Millipore, 05-802R) was used in western blot on human samples (fig 5). Eur J Appl Physiol (2015) ncbi
Articles Reviewed
  1. Kaur S, Nag A, Gangenahalli G, Sharma K. Peroxisome Proliferator Activated Receptor Gamma Sensitizes Non-small Cell Lung Carcinoma to Gamma Irradiation Induced Apoptosis. Front Genet. 2019;10:554 pubmed publisher
  2. Zhang J, Lee Y, Dang F, Gan W, Menon A, Katon J, et al. PTEN Methylation by NSD2 Controls Cellular Sensitivity to DNA Damage. Cancer Discov. 2019;: pubmed publisher
  3. Wang H, Huang F, Zhang Z, Wang P, Luo Y, Li H, et al. Feedback Activation of SGK3 and AKT Contributes to Rapamycin Resistance by Reactivating mTORC1/4EBP1 Axis via TSC2 in Breast Cancer. Int J Biol Sci. 2019;15:929-941 pubmed publisher
  4. Pietila M, Sahgal P, Peuhu E, Jäntti N, Paatero I, Närvä E, et al. SORLA regulates endosomal trafficking and oncogenic fitness of HER2. Nat Commun. 2019;10:2340 pubmed publisher
  5. Lee Y, Chen M, Lee J, Zhang J, Lin S, Fu T, et al. Reactivation of PTEN tumor suppressor for cancer treatment through inhibition of a MYC-WWP1 inhibitory pathway. Science. 2019;364: pubmed publisher
  6. Singh R, Peng S, Viswanath P, Sambandam V, Shen L, Rao X, et al. Non-canonical cMet regulation by vimentin mediates Plk1 inhibitor-induced apoptosis. EMBO Mol Med. 2019;: pubmed publisher
  7. Thauland T, Pellerin L, Ohgami R, Bacchetta R, Butte M. Case Study: Mechanism for Increased Follicular Helper T Cell Development in Activated PI3K Delta Syndrome. Front Immunol. 2019;10:753 pubmed publisher
  8. Sommars M, Ramachandran K, Senagolage M, Futtner C, Germain D, Allred A, et al. Dynamic repression by BCL6 controls the genome-wide liver response to fasting and steatosis. elife. 2019;8: pubmed publisher
  9. Hancock M, Meyer R, Mistry M, Khetani R, Wagschal A, Shin T, et al. Insulin Receptor Associates with Promoters Genome-wide and Regulates Gene Expression. Cell. 2019;177:722-736.e22 pubmed publisher
  10. Tsai C, Tsai C, Yi J, Kao H, Huang Y, Wang C, et al. Activin A regulates the epidermal growth factor receptor promoter by activating the PI3K/SP1 pathway in oral squamous cell carcinoma cells. Sci Rep. 2019;9:5197 pubmed publisher
  11. Chang H, Di T, Wang Y, Zeng X, Li G, Wan Q, et al. Seipin deletion in mice enhances phosphorylation and aggregation of tau protein through reduced neuronal PPARγ and insulin resistance. Neurobiol Dis. 2019;127:350-361 pubmed publisher
  12. Castel P, Cheng A, Cuevas Navarro A, Everman D, Papageorge A, Simanshu D, et al. RIT1 oncoproteins escape LZTR1-mediated proteolysis. Science. 2019;363:1226-1230 pubmed publisher
  13. Zhang S, Liu W, Yang Y, Sun K, Li S, Xu H, et al. Tmem30a Deficiency in endothelial cells impairs cell proliferation and angiogenesis. J Cell Sci. 2019;: pubmed publisher
  14. Cao J, Zhao M, Liu J, Zhang X, Pei Y, Wang J, et al. RACK1 Promotes Self-Renewal and Chemoresistance of Cancer Stem Cells in Human Hepatocellular Carcinoma through Stabilizing Nanog. Theranostics. 2019;9:811-828 pubmed publisher
  15. Teissier T, Quersin V, Gnemmi V, Daroux M, Howsam M, Delguste F, et al. Knockout of receptor for advanced glycation end-products attenuates age-related renal lesions. Aging Cell. 2019;18:e12850 pubmed publisher
  16. Yambire K, Fernández Mosquera L, Steinfeld R, Mühle C, Ikonen E, Milosevic I, et al. Mitochondrial biogenesis is transcriptionally repressed in lysosomal lipid storage diseases. elife. 2019;8: pubmed publisher
  17. Majumdar T, Sharma S, Kumar M, Hussain M, Chauhan N, Kalia I, et al. Tryptophan-kynurenine pathway attenuates β-catenin-dependent pro-parasitic role of STING-TICAM2-IRF3-IDO1 signalosome in Toxoplasma gondii infection. Cell Death Dis. 2019;10:161 pubmed publisher
  18. Mathieu J, Detraux D, Kuppers D, Wang Y, Cavanaugh C, Sidhu S, et al. Folliculin regulates mTORC1/2 and WNT pathways in early human pluripotency. Nat Commun. 2019;10:632 pubmed publisher
  19. Yin C, Zhu B, Zhang T, Liu T, Chen S, Liu Y, et al. Pharmacological Targeting of STK19 Inhibits Oncogenic NRAS-Driven Melanomagenesis. Cell. 2019;176:1113-1127.e16 pubmed publisher
  20. Wang W, Shen T, Dong B, Creighton C, Meng Y, Zhou W, et al. MAPK4 overexpression promotes tumor progression via noncanonical activation of AKT/mTOR signaling. J Clin Invest. 2019;: pubmed publisher
  21. Shen B, Vardy K, Hughes P, Tasdogan A, Zhao Z, Yue R, et al. Integrin alpha11 is an Osteolectin receptor and is required for the maintenance of adult skeletal bone mass. elife. 2019;8: pubmed publisher
  22. Ruscetti M, Leibold J, Bott M, Fennell M, Kulick A, Salgado N, et al. NK cell-mediated cytotoxicity contributes to tumor control by a cytostatic drug combination. Science. 2018;362:1416-1422 pubmed publisher
  23. Barros Silva J, Linn D, Steiner I, Guo G, Ali A, Pakula H, et al. Single-Cell Analysis Identifies LY6D as a Marker Linking Castration-Resistant Prostate Luminal Cells to Prostate Progenitors and Cancer. Cell Rep. 2018;25:3504-3518.e6 pubmed publisher
  24. Turowec J, Lau E, Wang X, Brown K, Fellouse F, Jawanda K, et al. Functional genomic characterization of a synthetic anti-HER3 antibody reveals a role for ubiquitination by RNF41 in the anti-proliferative response. J Biol Chem. 2019;294:1396-1409 pubmed publisher
  25. Schaffer T, Smith J, Cook E, Phan T, Margolis S. PKCε Inhibits Neuronal Dendritic Spine Development through Dual Phosphorylation of Ephexin5. Cell Rep. 2018;25:2470-2483.e8 pubmed publisher
  26. Zhou X, Zhang R, Zou Z, Shen X, Xie T, Xu C, et al. Hypoglycaemic effects of glimepiride in sulfonylurea receptor 1 deficient rat. Br J Pharmacol. 2019;176:478-490 pubmed publisher
  27. Zhao H, Martin E, Matalkah F, Shah N, Ivanov A, Ruppert J, et al. Conditional knockout of SHP2 in ErbB2 transgenic mice or inhibition in HER2-amplified breast cancer cell lines blocks oncogene expression and tumorigenesis. Oncogene. 2019;38:2275-2290 pubmed publisher
  28. Grohmann M, Wiede F, Dodd G, Gurzov E, Ooi G, Butt T, et al. Obesity Drives STAT-1-Dependent NASH and STAT-3-Dependent HCC. Cell. 2018;175:1289-1306.e20 pubmed publisher
  29. Wang F, Meng M, Mo B, Yang Y, Ji Y, Huang P, et al. Crosstalks between mTORC1 and mTORC2 variagate cytokine signaling to control NK maturation and effector function. Nat Commun. 2018;9:4874 pubmed publisher
  30. Bigenzahn J, Collu G, Kartnig F, Pieraks M, Vladimer G, Heinz L, et al. LZTR1 is a regulator of RAS ubiquitination and signaling. Science. 2018;362:1171-1177 pubmed publisher
  31. Liang C, Ma Y, Yong L, Yang C, Wang P, Liu X, et al. Y-box binding protein-1 promotes tumorigenesis and progression via the epidermal growth factor receptor/AKT pathway in spinal chordoma. Cancer Sci. 2019;110:166-179 pubmed publisher
  32. Hakuno D, Kimura M, Ito S, Satoh J, Nakashima Y, Horie T, et al. Hepatokine α1-Microglobulin Signaling Exacerbates Inflammation and Disturbs Fibrotic Repair in Mouse Myocardial Infarction. Sci Rep. 2018;8:16749 pubmed publisher
  33. Nie S, Tan Y, Zhang Z, Chen G, Xiong J, Hu D, et al. Bilateral Implantation of Shear Stress Modifier in ApoE Knockout Mouse Induces Cognitive Impairment and Tau Abnormalities. Front Aging Neurosci. 2018;10:303 pubmed publisher
  34. Mu L, Tu Z, Miao L, Ruan H, Kang N, Hei Y, et al. A phosphatidylinositol 4,5-bisphosphate redistribution-based sensing mechanism initiates a phagocytosis programing. Nat Commun. 2018;9:4259 pubmed publisher
  35. Park J, Lee J, Sheu K, Wang L, Balanis N, Nguyen K, et al. Reprogramming normal human epithelial tissues to a common, lethal neuroendocrine cancer lineage. Science. 2018;362:91-95 pubmed publisher
  36. Gerber T, Murawala P, Knapp D, Masselink W, Schuez M, Hermann S, et al. Single-cell analysis uncovers convergence of cell identities during axolotl limb regeneration. Science. 2018;362: pubmed publisher
  37. Yue D, Sun X. Idelalisib promotes Bim-dependent apoptosis through AKT/FoxO3a in hepatocellular carcinoma. Cell Death Dis. 2018;9:935 pubmed publisher
  38. Chen S, Yun F, Yao Y, Cao M, Zhang Y, Wang J, et al. USP38 critically promotes asthmatic pathogenesis by stabilizing JunB protein. J Exp Med. 2018;215:2850-2867 pubmed publisher
  39. Chorzalska A, Morgan J, Ahsan N, Treaba D, Olszewski A, Petersen M, et al. Bone marrow-specific loss of ABI1 induces myeloproliferative neoplasm with features resembling human myelofibrosis. Blood. 2018;: pubmed publisher
  40. Son S, Park S, Lee H, Siddiqi F, Lee J, Menzies F, et al. Leucine Signals to mTORC1 via Its Metabolite Acetyl-Coenzyme A. Cell Metab. 2019;29:192-201.e7 pubmed publisher
  41. Kim H, Mun Y, Lee K, Park Y, Park J, Park J, et al. T cell microvilli constitute immunological synaptosomes that carry messages to antigen-presenting cells. Nat Commun. 2018;9:3630 pubmed publisher
  42. Wang X, Li Q, Liu C, Hall P, Jiang J, Katchis C, et al. Lin28 Signaling Supports Mammalian PNS and CNS Axon Regeneration. Cell Rep. 2018;24:2540-2552.e6 pubmed publisher
  43. Song K, Kim J, Lee Y, Bae H, Lee H, Woo S, et al. Mitochondrial reprogramming via ATP5H loss promotes multimodal cancer therapy resistance. J Clin Invest. 2018;128:4098-4114 pubmed publisher
  44. Lu D, Song J, Sun Y, Qi F, Liu L, Jin Y, et al. Mutations of deubiquitinase OTUD1 are associated with autoimmune disorders. J Autoimmun. 2018;94:156-165 pubmed publisher
  45. Deason K, Troutman T, Jain A, Challa D, Mandraju R, Brewer T, et al. BCAP links IL-1R to the PI3K-mTOR pathway and regulates pathogenic Th17 cell differentiation. J Exp Med. 2018;215:2413-2428 pubmed publisher
  46. Stathopoulou C, Gangaplara A, Mallett G, Flomerfelt F, Liniany L, Knight D, et al. PD-1 Inhibitory Receptor Downregulates Asparaginyl Endopeptidase and Maintains Foxp3 Transcription Factor Stability in Induced Regulatory T Cells. Immunity. 2018;49:247-263.e7 pubmed publisher
  47. Muller T, Braud S, Jüttner R, Voigt B, Paulick K, Sheean M, et al. Neuregulin 3 promotes excitatory synapse formation on hippocampal interneurons. EMBO J. 2018;37: pubmed publisher
  48. Zhu L, Xie X, Zhang L, Wang H, Jie Z, Zhou X, et al. TBK-binding protein 1 regulates IL-15-induced autophagy and NKT cell survival. Nat Commun. 2018;9:2812 pubmed publisher
  49. Xie H, Wang Y, Zhang H, Fan Q, Dai D, Zhuang L, et al. Tubular epithelial C1orf54 mediates protection and recovery from acute kidney injury. J Cell Mol Med. 2018;22:4985-4996 pubmed publisher
  50. Beyer S, Schwalm S, Pfeilschifter J, Huwiler A. Renal Mesangial Cells Isolated from Sphingosine Kinase 2 Transgenic Mice Show Reduced Proliferation and are More Sensitive to Stress-Induced Apoptosis. Cell Physiol Biochem. 2018;47:2522-2533 pubmed publisher
  51. Matesanz N, Nikolic I, Leiva M, Pulgarín Alfaro M, Santamans A, Bernardo E, et al. p38α blocks brown adipose tissue thermogenesis through p38δ inhibition. PLoS Biol. 2018;16:e2004455 pubmed publisher
  52. Wang W, Xia Z, Farre J, Subramani S. TRIM37 deficiency induces autophagy through deregulating the MTORC1-TFEB axis. Autophagy. 2018;14:1574-1585 pubmed publisher
  53. Rapino F, Delaunay S, Rambow F, Zhou Z, Tharun L, de Tullio P, et al. Codon-specific translation reprogramming promotes resistance to targeted therapy. Nature. 2018;558:605-609 pubmed publisher
  54. Fan P, Narzisi G, Jayaprakash A, Venturini E, Robine N, Smibert P, et al. YES1 amplification is a mechanism of acquired resistance to EGFR inhibitors identified by transposon mutagenesis and clinical genomics. Proc Natl Acad Sci U S A. 2018;115:E6030-E6038 pubmed publisher
  55. Ruess D, Heynen G, Ciecielski K, Ai J, Berninger A, Kabacaoglu D, et al. Mutant KRAS-driven cancers depend on PTPN11/SHP2 phosphatase. Nat Med. 2018;24:954-960 pubmed publisher
  56. Baumgartner C, Toifl S, Farlik M, Halbritter F, Scheicher R, Fischer I, et al. An ERK-Dependent Feedback Mechanism Prevents Hematopoietic Stem Cell Exhaustion. Cell Stem Cell. 2018;22:879-892.e6 pubmed publisher
  57. Mitchell K, Barreyro L, Todorova T, Taylor S, Antony Debré I, Narayanagari S, et al. IL1RAP potentiates multiple oncogenic signaling pathways in AML. J Exp Med. 2018;215:1709-1727 pubmed publisher
  58. Khalifeh Soltani A, Gupta D, Ha A, Podolsky M, Datta R, Atabai K. The Mfge8-α8β1-PTEN pathway regulates airway smooth muscle contraction in allergic inflammation. FASEB J. 2018;:fj201800109R pubmed publisher
  59. Wang X, Du C, He X, Deng X, He Y, Zhou X. MiR-4463 inhibits the migration of human aortic smooth muscle cells by AMOT. Biosci Rep. 2018;38: pubmed publisher
  60. Rajgor D, Sanderson T, Amici M, Collingridge G, Hanley J. NMDAR-dependent Argonaute 2 phosphorylation regulates miRNA activity and dendritic spine plasticity. EMBO J. 2018;37: pubmed publisher
  61. Li H, Zhang P, Zhang Q, Li C, Zou W, Chang Z, et al. WWP2 is a physiological ubiquitin ligase for phosphatase and tensin homolog (PTEN) in mice. J Biol Chem. 2018;293:8886-8899 pubmed publisher
  62. Salomè M, Magee A, Yalla K, Chaudhury S, Sarrou E, Carmody R, et al. A Trib2-p38 axis controls myeloid leukaemia cell cycle and stress response signalling. Cell Death Dis. 2018;9:443 pubmed publisher
  63. Mirzamohammadi F, Kozlova A, Papaioannou G, Paltrinieri E, Ayturk U, Kobayashi T. Distinct molecular pathways mediate Mycn and Myc-regulated miR-17-92 microRNA action in Feingold syndrome mouse models. Nat Commun. 2018;9:1352 pubmed publisher
  64. Chiang A, Fowler S, Savjani R, Hilsenbeck S, Wallace C, Cirrito J, et al. Combination anti-Aβ treatment maximizes cognitive recovery and rebalances mTOR signaling in APP mice. J Exp Med. 2018;215:1349-1364 pubmed publisher
  65. Muhar M, Ebert A, Neumann T, Umkehrer C, Jude J, Wieshofer C, et al. SLAM-seq defines direct gene-regulatory functions of the BRD4-MYC axis. Science. 2018;360:800-805 pubmed publisher
  66. Han Y, Liu Q, Hou J, Gu Y, Zhang Y, Chen Z, et al. Tumor-Induced Generation of Splenic Erythroblast-like Ter-Cells Promotes Tumor Progression. Cell. 2018;173:634-648.e12 pubmed publisher
  67. Zheng C, Wang J, Lin M, Zhang P, Liu L, Lin J, et al. CDK5RAP3 suppresses Wnt/β-catenin signaling by inhibiting AKT phosphorylation in gastric cancer. J Exp Clin Cancer Res. 2018;37:59 pubmed publisher
  68. Ng P, Li J, Jeong K, Shao S, Chen H, Tsang Y, et al. Systematic Functional Annotation of Somatic Mutations in Cancer. Cancer Cell. 2018;33:450-462.e10 pubmed publisher
  69. zur Nedden S, Eith R, Schwarzer C, Zanetti L, Seitter H, Fresser F, et al. Protein kinase N1 critically regulates cerebellar development and long-term function. J Clin Invest. 2018;128:2076-2088 pubmed publisher
  70. Vlachogiannis G, Hedayat S, Vatsiou A, Jamin Y, Fernández Mateos J, Khan K, et al. Patient-derived organoids model treatment response of metastatic gastrointestinal cancers. Science. 2018;359:920-926 pubmed publisher
  71. Yurchenko M, Skjesol A, Ryan L, Richard G, Kandasamy R, Wang N, et al. SLAMF1 is required for TLR4-mediated TRAM-TRIF-dependent signaling in human macrophages. J Cell Biol. 2018;217:1411-1429 pubmed publisher
  72. Patra D, DeLassus E, Mueller J, Abou Ezzi G, Sandell L. Site-1 protease regulates skeletal stem cell population and osteogenic differentiation in mice. Biol Open. 2018;7: pubmed publisher
  73. Nan H, Han L, Ma J, Yang C, Su R, He J. STX3 represses the stability of the tumor suppressor PTEN to activate the PI3K-Akt-mTOR signaling and promotes the growth of breast cancer cells. Biochim Biophys Acta Mol Basis Dis. 2018;1864:1684-1692 pubmed publisher
  74. Janes M, Zhang J, Li L, Hansen R, Peters U, Guo X, et al. Targeting KRAS Mutant Cancers with a Covalent G12C-Specific Inhibitor. Cell. 2018;172:578-589.e17 pubmed publisher
  75. Shen Q, Zhang Q, Shi Y, Shi Q, Jiang Y, Gu Y, et al. Tet2 promotes pathogen infection-induced myelopoiesis through mRNA oxidation. Nature. 2018;554:123-127 pubmed publisher
  76. Saunders B, Rudnicka C, Filipovska A, Davies S, Ward N, Hricova J, et al. Shining LIGHT on the metabolic role of the cytokine TNFSF14 and the implications on hepatic IL-6 production. Immunol Cell Biol. 2018;96:41-53 pubmed publisher
  77. Souma T, Thomson B, Heinen S, Carota I, Yamaguchi S, Onay T, et al. Context-dependent functions of angiopoietin 2 are determined by the endothelial phosphatase VEPTP. Proc Natl Acad Sci U S A. 2018;115:1298-1303 pubmed publisher
  78. Shen L, Qu X, Li H, Xu C, Wei M, Wang Q, et al. NDRG2 facilitates colorectal cancer differentiation through the regulation of Skp2-p21/p27 axis. Oncogene. 2018;37:1759-1774 pubmed publisher
  79. Ambrogio C, Köhler J, Zhou Z, Wang H, Paranal R, Li J, et al. KRAS Dimerization Impacts MEK Inhibitor Sensitivity and Oncogenic Activity of Mutant KRAS. Cell. 2018;172:857-868.e15 pubmed publisher
  80. Bekkering S, Arts R, Novakovic B, Kourtzelis I, van der Heijden C, Li Y, et al. Metabolic Induction of Trained Immunity through the Mevalonate Pathway. Cell. 2018;172:135-146.e9 pubmed publisher
  81. Frattini V, Pagnotta S, Tala -, Fan J, Russo M, Lee S, et al. A metabolic function of FGFR3-TACC3 gene fusions in cancer. Nature. 2018;553:222-227 pubmed publisher
  82. Khalil S, Delehanty L, Grado S, Holy M, White Z, Freeman K, et al. Iron modulation of erythropoiesis is associated with Scribble-mediated control of the erythropoietin receptor. J Exp Med. 2018;215:661-679 pubmed publisher
  83. Barrow A, Edeling M, Trifonov V, Luo J, Goyal P, Bohl B, et al. Natural Killer Cells Control Tumor Growth by Sensing a Growth Factor. Cell. 2018;172:534-548.e19 pubmed publisher
  84. Ka M, Kim W. ANKRD11 associated with intellectual disability and autism regulates dendrite differentiation via the BDNF/TrkB signaling pathway. Neurobiol Dis. 2018;111:138-152 pubmed publisher
  85. Wang J, Ye Q, Cao Y, Guo Y, Huang X, Mi W, et al. Snail determines the therapeutic response to mTOR kinase inhibitors by transcriptional repression of 4E-BP1. Nat Commun. 2017;8:2207 pubmed publisher
  86. Rajbhandari P, Thomas B, Feng A, Hong C, Wang J, Vergnes L, et al. IL-10 Signaling Remodels Adipose Chromatin Architecture to Limit Thermogenesis and Energy Expenditure. Cell. 2018;172:218-233.e17 pubmed publisher
  87. Coelho M, de Carné Trécesson S, Rana S, Zecchin D, Moore C, Molina Arcas M, et al. Oncogenic RAS Signaling Promotes Tumor Immunoresistance by Stabilizing PD-L1 mRNA. Immunity. 2017;47:1083-1099.e6 pubmed publisher
  88. Galan A, Jmaeff S, Barcelona P, Brahimi F, Sarunic M, Saragovi H. In retinitis pigmentosa TrkC.T1-dependent vectorial Erk activity upregulates glial TNF-α, causing selective neuronal death. Cell Death Dis. 2017;8:3222 pubmed publisher
  89. Turkington H, Juozapaitis M, Tsolakos N, Corrales Aguilar E, Schwemmle M, Hale B. Unexpected Functional Divergence of Bat Influenza Virus NS1 Proteins. J Virol. 2018;92: pubmed publisher
  90. Yu R, Longo J, van Leeuwen J, Mullen P, Ba Alawi W, Haibe Kains B, et al. Statin-Induced Cancer Cell Death Can Be Mechanistically Uncoupled from Prenylation of RAS Family Proteins. Cancer Res. 2018;78:1347-1357 pubmed publisher
  91. Cho M, Lee J, Shin M, Kim H, Choi Y, Rho S, et al. TSC-22 inhibits CSF-1R function and induces apoptosis in cervical cancer. Oncotarget. 2017;8:97990-98003 pubmed publisher
  92. Kim M, Morales L, Baek M, Slaga T, DiGiovanni J, Kim D. UVB-induced nuclear translocation of TC-PTP by AKT/14-3-3? axis inhibits keratinocyte survival and proliferation. Oncotarget. 2017;8:90674-90692 pubmed publisher
  93. Muro R, Nitta T, Nakano K, Okamura T, Takayanagi H, Suzuki H. γδTCR recruits the Syk/PI3K axis to drive proinflammatory differentiation program. J Clin Invest. 2018;128:415-426 pubmed publisher
  94. Sun H, Krauss R, Chang J, Teng B. PCSK9 deficiency reduces atherosclerosis, apolipoprotein B secretion, and endothelial dysfunction. J Lipid Res. 2018;59:207-223 pubmed publisher
  95. Kishore M, Cheung K, Fu H, Bonacina F, Wang G, Coe D, et al. Regulatory T Cell Migration Is Dependent on Glucokinase-Mediated Glycolysis. Immunity. 2017;47:875-889.e10 pubmed publisher
  96. Ni Z, HE J, Wu Y, Hu C, Dai X, Yan X, et al. AKT-mediated phosphorylation of ATG4B impairs mitochondrial activity and enhances the Warburg effect in hepatocellular carcinoma cells. Autophagy. 2018;14:685-701 pubmed publisher
  97. Schafer S, Viswanathan S, Widjaja A, Lim W, Moreno Moral A, Delaughter D, et al. IL-11 is a crucial determinant of cardiovascular fibrosis. Nature. 2017;552:110-115 pubmed publisher
  98. Urbanska M, Gozdz A, Macias M, Cymerman I, Liszewska E, Kondratiuk I, et al. GSK3β Controls mTOR and Prosurvival Signaling in Neurons. Mol Neurobiol. 2018;55:6050-6062 pubmed publisher
  99. Bostner J, Alayev A, Berman A, Fornander T, Nordenskjold B, Holz M, et al. Raptor localization predicts prognosis and tamoxifen response in estrogen receptor-positive breast cancer. Breast Cancer Res Treat. 2018;168:17-27 pubmed publisher
  100. Ameen G, Mora S. Cbl downregulation increases RBP4 expression in adipocytes of female mice. J Endocrinol. 2018;236:29-41 pubmed publisher
  101. Redka D, Gutschow M, Grinstein S, Canton J. Differential ability of proinflammatory and anti-inflammatory macrophages to perform macropinocytosis. Mol Biol Cell. 2018;29:53-65 pubmed publisher
  102. Meng Z, Tao W, Sun J, Wang Q, Mi L, Lin J. Uncoupling Exercise Bioenergetics From Systemic Metabolic Homeostasis by Conditional Inactivation of Baf60 in Skeletal Muscle. Diabetes. 2018;67:85-97 pubmed publisher
  103. Zhang R, Li J, Yan X, Jin K, Li W, Xu J, et al. SODD promotes glucose uptake of colorectal cancer cells via AKT pathway. Cell Biol Int. 2017;: pubmed publisher
  104. Kang H, Kumar D, Liao G, Lichti Kaiser K, Gerrish K, Liao X, et al. GLIS3 is indispensable for TSH/TSHR-dependent thyroid hormone biosynthesis and follicular cell proliferation. J Clin Invest. 2017;127:4326-4337 pubmed publisher
  105. Xue X, Bredell B, Anderson E, Martin A, Mays C, Nagao Kitamoto H, et al. Quantitative proteomics identifies STEAP4 as a critical regulator of mitochondrial dysfunction linking inflammation and colon cancer. Proc Natl Acad Sci U S A. 2017;114:E9608-E9617 pubmed publisher
  106. Frey J, Kim S, Li Z, Wolfgang M, Riddle R. β-Catenin Directs Long-Chain Fatty Acid Catabolism in the Osteoblasts of Male Mice. Endocrinology. 2018;159:272-284 pubmed publisher
  107. Thaler S, Schmidt M, Roβwag S, Thiede G, Schad A, Sleeman J. Proteasome inhibitors prevent bi-directional HER2/estrogen-receptor cross-talk leading to cell death in endocrine and lapatinib-resistant HER2+/ER+ breast cancer cells. Oncotarget. 2017;8:72281-72301 pubmed publisher
  108. Zeng L, Kang R, Zhu S, Wang X, Cao L, Wang H, et al. ALK is a therapeutic target for lethal sepsis. Sci Transl Med. 2017;9: pubmed publisher
  109. Mai W, Gosa L, Daniëls V, Ta L, Tsang J, Higgins B, et al. Cytoplasmic p53 couples oncogene-driven glucose metabolism to apoptosis and is a therapeutic target in glioblastoma. Nat Med. 2017;23:1342-1351 pubmed publisher
  110. Xie Z, Enkhjargal B, Wu L, Zhou K, Sun C, Hu X, et al. Exendin-4 attenuates neuronal death via GLP-1R/PI3K/Akt pathway in early brain injury after subarachnoid hemorrhage in rats. Neuropharmacology. 2018;128:142-151 pubmed publisher
  111. Bagarolli R, Tobar N, Oliveira A, Araújo T, Carvalho B, Rocha G, et al. Probiotics modulate gut microbiota and improve insulin sensitivity in DIO mice. J Nutr Biochem. 2017;50:16-25 pubmed publisher
  112. Wang N, Li J, Zhao T, Li S, Shen C, Li D, et al. FGF-21 Plays a Crucial Role in the Glucose Uptake of Activated Monocytes. Inflammation. 2018;41:73-80 pubmed publisher
  113. Zhao Z, Jia Q, Wu M, Xie X, Wang Y, Song G, et al. Degalactotigonin, a Natural Compound from Solanum nigrum L., Inhibits Growth and Metastasis of Osteosarcoma through GSK3β Inactivation-Mediated Repression of the Hedgehog/Gli1 Pathway. Clin Cancer Res. 2018;24:130-144 pubmed publisher
  114. Tarjus A, Maase M, Jeggle P, Martínez Martínez E, Fassot C, Loufrani L, et al. The endothelial ?ENaC contributes to vascular endothelial function in vivo. PLoS ONE. 2017;12:e0185319 pubmed publisher
  115. Zhang F, Virshup D, Cheong J. Oncogenic RAS-induced CK1α drives nuclear FOXO proteolysis. Oncogene. 2018;37:363-376 pubmed publisher
  116. Xu Y, Wang Y, Yao A, Xu Z, Dou H, Shen S, et al. Low Frequency Magnetic Fields Induce Autophagy-associated Cell Death in Lung Cancer through miR-486-mediated Inhibition of Akt/mTOR Signaling Pathway. Sci Rep. 2017;7:11776 pubmed publisher
  117. Kim J, Park D, Bae H, Park D, Kim D, Lee C, et al. Impaired angiopoietin/Tie2 signaling compromises Schlemm's canal integrity and induces glaucoma. J Clin Invest. 2017;127:3877-3896 pubmed publisher
  118. Hwangbo C, Wu J, Papangeli I, Adachi T, Sharma B, Park S, et al. Endothelial APLNR regulates tissue fatty acid uptake and is essential for apelin's glucose-lowering effects. Sci Transl Med. 2017;9: pubmed publisher
  119. Comiskey D, Jacob A, Sanford B, Montes M, Goodwin A, Steiner H, et al. A novel mouse model of rhabdomyosarcoma underscores the dichotomy of MDM2-ALT1 function in vivo. Oncogene. 2018;37:95-106 pubmed publisher
  120. Zhao F, Franco H, Rodriguez K, Brown P, Tsai M, Tsai S, et al. Elimination of the male reproductive tract in the female embryo is promoted by COUP-TFII in mice. Science. 2017;357:717-720 pubmed publisher
  121. Simond A, Rao T, Zuo D, Zhao J, Muller W. ErbB2-positive mammary tumors can escape PI3K-p110α loss through downregulation of the Pten tumor suppressor. Oncogene. 2017;36:6059-6066 pubmed publisher
  122. Liu X, Zhou X, Xu H, He Z, Shi X, Wu S. SLC34A2 Regulates the Proliferation, Migration, and Invasion of Human Osteosarcoma Cells Through PTEN/PI3K/AKT Signaling. DNA Cell Biol. 2017;36:775-780 pubmed publisher
  123. Peterson J, Lin B, Shin J, Phelan P, Tsichlis P, Schwob J, et al. Replication of JC Virus DNA in the G144 Oligodendrocyte Cell Line Is Dependent Upon Akt. J Virol. 2017;91: pubmed publisher
  124. Chang S, Kohlgruber A, Mizoguchi F, Michelet X, Wolf B, Wei K, et al. Stromal cell cadherin-11 regulates adipose tissue inflammation and diabetes. J Clin Invest. 2017;127:3300-3312 pubmed publisher
  125. Ogura H, Nagatake Kobayashi Y, Adachi J, Tomonaga T, Fujita N, Katayama R. TKI-addicted ROS1-rearranged cells are destined to survival or death by the intensity of ROS1 kinase activity. Sci Rep. 2017;7:5519 pubmed publisher
  126. Guilford B, Parson J, Grote C, Vick S, Ryals J, Wright D. Increased FNDC5 is associated with insulin resistance in high fat-fed mice. Physiol Rep. 2017;5: pubmed publisher
  127. Baumann C, Ullrich A, Torka R. GAS6-expressing and self-sustaining cancer cells in 3D spheroids activate the PDK-RSK-mTOR pathway for survival and drug resistance. Mol Oncol. 2017;11:1430-1447 pubmed publisher
  128. Guo J, Jayaprakash P, Dan J, Wise P, Jang G, Liang C, et al. PRAS40 Connects Microenvironmental Stress Signaling to Exosome-Mediated Secretion. Mol Cell Biol. 2017;37: pubmed publisher
  129. Laviolette L, Mermoud J, Calvo I, Olson N, Boukhali M, Steinlein O, et al. Negative regulation of EGFR signalling by the human folliculin tumour suppressor protein. Nat Commun. 2017;8:15866 pubmed publisher
  130. Patel N, Garikapati K, Pandita R, Singh D, Pandita T, Bhadra U, et al. miR-15a/miR-16 down-regulates BMI1, impacting Ub-H2A mediated DNA repair and breast cancer cell sensitivity to doxorubicin. Sci Rep. 2017;7:4263 pubmed publisher
  131. Mamo T, Wittern A, Kleppa M, Bohnenpoll T, Weiss A, Kispert A. BMP4 uses several different effector pathways to regulate proliferation and differentiation in the epithelial and mesenchymal tissue compartments of the developing mouse ureter. Hum Mol Genet. 2017;26:3553-3563 pubmed publisher
  132. Wei X, Guo L, Liu Y, Zhou S, Liu Y, Dou X, et al. Synthesis of cytochrome c oxidase 1 (SCO1) inhibits insulin sensitivity by decreasing copper levels in adipocytes. Biochem Biophys Res Commun. 2017;491:814-820 pubmed publisher
  133. Akiel M, Guo C, Li X, Rajasekaran D, Mendoza R, Robertson C, et al. IGFBP7 Deletion Promotes Hepatocellular Carcinoma. Cancer Res. 2017;77:4014-4025 pubmed publisher
  134. Oblinger J, Burns S, Huang J, Pan L, Ren Y, Shen R, et al. Overexpression of eIF4F components in meningiomas and suppression of meningioma cell growth by inhibiting translation initiation. Exp Neurol. 2018;299:299-307 pubmed publisher
  135. Pereira R, Tadinada S, Zasadny F, Oliveira K, Pires K, Olvera A, et al. OPA1 deficiency promotes secretion of FGF21 from muscle that prevents obesity and insulin resistance. EMBO J. 2017;36:2126-2145 pubmed publisher
  136. Zhang K, Myllymäki S, Gao P, Devarajan R, Kytölä V, Nykter M, et al. Oncogenic K-Ras upregulates ITGA6 expression via FOSL1 to induce anoikis resistance and synergizes with αV-Class integrins to promote EMT. Oncogene. 2017;36:5681-5694 pubmed publisher
  137. Wang B, Gu Q, Li J. DOC-2/DAB2 interactive protein regulates proliferation and mobility of nasopharyngeal carcinoma cells by targeting PI3K/Akt pathway. Oncol Rep. 2017;38:317-324 pubmed publisher
  138. Shi Y, Ping Y, Zhou W, He Z, Chen C, Bian B, et al. Tumour-associated macrophages secrete pleiotrophin to promote PTPRZ1 signalling in glioblastoma stem cells for tumour growth. Nat Commun. 2017;8:15080 pubmed publisher
  139. Sinha S, Thomas D, Chan S, Gao Y, Brunen D, Torabi D, et al. Systematic discovery of mutation-specific synthetic lethals by mining pan-cancer human primary tumor data. Nat Commun. 2017;8:15580 pubmed publisher
  140. Miyamoto T, Lo P, Saichi N, Ueda K, Hirata M, Tanikawa C, et al. Argininosuccinate synthase 1 is an intrinsic Akt repressor transactivated by p53. Sci Adv. 2017;3:e1603204 pubmed publisher
  141. Tsuda T, Takefuji M, Wettschureck N, Kotani K, Morimoto R, Okumura T, et al. Corticotropin releasing hormone receptor 2 exacerbates chronic cardiac dysfunction. J Exp Med. 2017;214:1877-1888 pubmed publisher
  142. Mendoza A, Fang V, Chen C, Serasinghe M, Verma A, Muller J, et al. Lymphatic endothelial S1P promotes mitochondrial function and survival in naive T cells. Nature. 2017;546:158-161 pubmed publisher
  143. Hossain M, Oomura Y, Katafuchi T. Glucose Can Epigenetically Alter the Gene Expression of Neurotrophic Factors in the Murine Brain Cells. Mol Neurobiol. 2018;55:3408-3425 pubmed publisher
  144. Wang B, Jie Z, Joo D, Ordureau A, Liu P, Gan W, et al. TRAF2 and OTUD7B govern a ubiquitin-dependent switch that regulates mTORC2 signalling. Nature. 2017;545:365-369 pubmed publisher
  145. Ventura E, Weller M, Burghardt I. Cutting Edge: ERK1 Mediates the Autocrine Positive Feedback Loop of TGF-? and Furin in Glioma-Initiating Cells. J Immunol. 2017;198:4569-4574 pubmed publisher
  146. Hu L, Liang S, Chen H, Lv T, Wu J, Chen D, et al. ΔNp63α is a common inhibitory target in oncogenic PI3K/Ras/Her2-induced cell motility and tumor metastasis. Proc Natl Acad Sci U S A. 2017;114:E3964-E3973 pubmed publisher
  147. Gong B, Shen W, Xiao W, Meng Y, Meng A, Jia S. The Sec14-like phosphatidylinositol transfer proteins Sec14l3/SEC14L2 act as GTPase proteins to mediate Wnt/Ca2+ signaling. elife. 2017;6: pubmed publisher
  148. Kapil S, Sharma B, Patil M, Elattar S, Yuan J, Hou S, et al. The cell polarity protein Scrib functions as a tumor suppressor in liver cancer. Oncotarget. 2017;8:26515-26531 pubmed publisher
  149. Krag T, Ruiz Ruiz C, Vissing J. Glycogen Synthesis in Glycogenin 1-Deficient Patients: A Role for Glycogenin 2 in Muscle. J Clin Endocrinol Metab. 2017;102:2690-2700 pubmed publisher
  150. Arcego D, Toniazzo A, Krolow R, Lampert C, Berlitz C, Dos Santos Garcia E, et al. Impact of High-Fat Diet and Early Stress on Depressive-Like Behavior and Hippocampal Plasticity in Adult Male Rats. Mol Neurobiol. 2018;55:2740-2753 pubmed publisher
  151. Riemer P, Rydenfelt M, Marks M, van Eunen K, Thedieck K, Herrmann B, et al. Oncogenic β-catenin and PIK3CA instruct network states and cancer phenotypes in intestinal organoids. J Cell Biol. 2017;216:1567-1577 pubmed publisher
  152. Zhou X, Packialakshmi B, Xiao Y, Nurmukhambetova S, Lees J. Progression of experimental autoimmune encephalomyelitis is associated with up-regulation of major sodium transporters in the mouse kidney cortex under a normal salt diet. Cell Immunol. 2017;317:18-25 pubmed publisher
  153. Cai C, Qian L, Jiang S, Sun Y, Wang Q, Ma D, et al. Loss-of-function myostatin mutation increases insulin sensitivity and browning of white fat in Meishan pigs. Oncotarget. 2017;8:34911-34922 pubmed publisher
  154. Tawo R, Pokrzywa W, Kevei E, Akyuz M, Balaji V, Adrian S, et al. The Ubiquitin Ligase CHIP Integrates Proteostasis and Aging by Regulation of Insulin Receptor Turnover. Cell. 2017;169:470-482.e13 pubmed publisher
  155. Vaishnavi A, Schubert L, Rix U, Marek L, Le A, Keysar S, et al. EGFR Mediates Responses to Small-Molecule Drugs Targeting Oncogenic Fusion Kinases. Cancer Res. 2017;77:3551-3563 pubmed publisher
  156. Kim D, Ko H, Park G, Hur D, Kim Y, Yang J. Vandetanib and ADAM inhibitors synergistically attenuate the pathological migration of EBV-infected retinal pigment epithelial cells by regulating the VEGF-mediated MAPK pathway. Exp Ther Med. 2017;13:1415-1425 pubmed publisher
  157. Yang X, Qi L, Lin F, Ou Z. The role of the chemokine receptor XCR1 in breast cancer cells. Breast Cancer (Dove Med Press). 2017;9:227-236 pubmed publisher
  158. Zhang X, Spiegelman N, Nelson O, Jing H, Lin H. SIRT6 regulates Ras-related protein R-Ras2 by lysine defatty-acylation. elife. 2017;6: pubmed publisher
  159. Wang K, Liu W, Song Y, Wu X, Zhang Y, Li S, et al. The role of angiopoietin-2 in nucleus pulposus cells during human intervertebral disc degeneration. Lab Invest. 2017;97:971-982 pubmed publisher
  160. Xiao Z, Gaertner S, Morresi Hauf A, Genzel R, Duell T, Ullrich A, et al. Metformin Triggers Autophagy to Attenuate Drug-Induced Apoptosis in NSCLC Cells, with Minor Effects on Tumors of Diabetic Patients. Neoplasia. 2017;19:385-395 pubmed publisher
  161. Xiao Y, Yang Z, Wu Q, Jiang X, Yuan Y, Chang W, et al. Cucurbitacin B Protects Against Pressure Overload Induced Cardiac Hypertrophy. J Cell Biochem. 2017;118:3899-3910 pubmed publisher
  162. Yan X, Zhu Z, Xu S, Yang L, Liao X, Zheng M, et al. MicroRNA-140-5p inhibits hepatocellular carcinoma by directly targeting the unique isomerase Pin1 to block multiple cancer-driving pathways. Sci Rep. 2017;7:45915 pubmed publisher
  163. Ahmed S, Macara I. The Par3 polarity protein is an exocyst receptor essential for mammary cell survival. Nat Commun. 2017;8:14867 pubmed publisher
  164. Guo Q, He J, Shen F, Zhang W, Yang X, Zhang C, et al. TCN, an AKT inhibitor, exhibits potent antitumor activity and enhances radiosensitivity in hypoxic esophageal squamous cell carcinoma in vitro and in vivo. Oncol Lett. 2017;13:949-954 pubmed publisher
  165. Zhang X, Fan J, Wang S, Li Y, Wang Y, Li S, et al. Targeting CD47 and Autophagy Elicited Enhanced Antitumor Effects in Non-Small Cell Lung Cancer. Cancer Immunol Res. 2017;5:363-375 pubmed publisher
  166. He W, Wang C, Mu R, Liang P, Huang Z, Zhang J, et al. MiR-21 is required for anti-tumor immune response in mice: an implication for its bi-directional roles. Oncogene. 2017;36:4212-4223 pubmed publisher
  167. Cai W, Sakaguchi M, Kleinridders A, Gonzalez Del Pino G, Dreyfuss J, O Neill B, et al. Domain-dependent effects of insulin and IGF-1 receptors on signalling and gene expression. Nat Commun. 2017;8:14892 pubmed publisher
  168. Xiong G, Hindi S, Mann A, Gallot Y, Bohnert K, Cavener D, et al. The PERK arm of the unfolded protein response regulates satellite cell-mediated skeletal muscle regeneration. elife. 2017;6: pubmed publisher
  169. Liu S, Gao G, Yan D, Chen X, Yao X, Guo S, et al. Effects of miR-145-5p through NRAS on the cell proliferation, apoptosis, migration, and invasion in melanoma by inhibiting MAPK and PI3K/AKT pathways. Cancer Med. 2017;6:819-833 pubmed publisher
  170. Lei L, Chen C, Zhao J, Wang H, Guo M, Zhou Y, et al. Targeted Expression of miR-7 Operated by TTF-1 Promoter Inhibited the Growth of Human Lung Cancer through the NDUFA4 Pathway. Mol Ther Nucleic Acids. 2017;6:183-197 pubmed publisher
  171. Lee H, Kim M, Baek M, Morales L, Jang I, Slaga T, et al. Targeted disruption of TC-PTP in the proliferative compartment augments STAT3 and AKT signaling and skin tumor development. Sci Rep. 2017;7:45077 pubmed publisher
  172. Lu X, Horner J, Paul E, Shang X, Troncoso P, Deng P, et al. Effective combinatorial immunotherapy for castration-resistant prostate cancer. Nature. 2017;543:728-732 pubmed publisher
  173. Li N, Xue W, Yuan H, Dong B, Ding Y, Liu Y, et al. AKT-mediated stabilization of histone methyltransferase WHSC1 promotes prostate cancer metastasis. J Clin Invest. 2017;127:1284-1302 pubmed publisher
  174. Gupta A, Anjomani Virmouni S, Koundouros N, Dimitriadi M, Choo Wing R, Valle A, et al. PARK2 Depletion Connects Energy and Oxidative Stress to PI3K/Akt Activation via PTEN S-Nitrosylation. Mol Cell. 2017;65:999-1013.e7 pubmed publisher
  175. Merhi A, Delree P, Marini A. The metabolic waste ammonium regulates mTORC2 and mTORC1 signaling. Sci Rep. 2017;7:44602 pubmed publisher
  176. Panigrahi S, Manterola M, Wolgemuth D. Meiotic failure in cyclin A1-deficient mouse spermatocytes triggers apoptosis through intrinsic and extrinsic signaling pathways and 14-3-3 proteins. PLoS ONE. 2017;12:e0173926 pubmed publisher
  177. Sahu U, Choudhury A, Parvez S, Biswas S, Kar S. Induction of intestinal stemness and tumorigenicity by aberrant internalization of commensal non-pathogenic E. coli. Cell Death Dis. 2017;8:e2667 pubmed publisher
  178. CAROMILE L, Dortche K, Rahman M, Grant C, Stoddard C, Ferrer F, et al. PSMA redirects cell survival signaling from the MAPK to the PI3K-AKT pathways to promote the progression of prostate cancer. Sci Signal. 2017;10: pubmed publisher
  179. Cherniack A, Shen H, Walter V, Stewart C, Murray B, Bowlby R, et al. Integrated Molecular Characterization of Uterine Carcinosarcoma. Cancer Cell. 2017;31:411-423 pubmed publisher
  180. Su S, Liao J, Liu J, Huang D, He C, Chen F, et al. Blocking the recruitment of naive CD4+ T cells reverses immunosuppression in breast cancer. Cell Res. 2017;27:461-482 pubmed publisher
  181. Jacobs B, McNally R, Kim K, Blanco R, Privett R, You J, et al. Identification of mechanically regulated phosphorylation sites on tuberin (TSC2) that control mechanistic target of rapamycin (mTOR) signaling. J Biol Chem. 2017;292:6987-6997 pubmed publisher
  182. Koyama Y, Wang P, Liang S, Iwaisako K, Liu X, Xu J, et al. Mesothelin/mucin 16 signaling in activated portal fibroblasts regulates cholestatic liver fibrosis. J Clin Invest. 2017;127:1254-1270 pubmed publisher
  183. Dogan A, Demirci S, Apdik H, Bayrak O, Gulluoglu S, Tuysuz E, et al. A new hope for obesity management: Boron inhibits adipogenesis in progenitor cells through the Wnt/β-catenin pathway. Metabolism. 2017;69:130-142 pubmed publisher
  184. Samuel S, Ghosh S, Majeed Y, Arunachalam G, Emara M, Ding H, et al. Metformin represses glucose starvation induced autophagic response in microvascular endothelial cells and promotes cell death. Biochem Pharmacol. 2017;132:118-132 pubmed publisher
  185. Eppler F, Quast T, Kolanus W. Dynamin2 controls Rap1 activation and integrin clustering in human T lymphocyte adhesion. PLoS ONE. 2017;12:e0172443 pubmed publisher
  186. Loo L, Bougen Zhukov N, Tan W. Early spatiotemporal-specific changes in intermediate signals are predictive of cytotoxic sensitivity to TNFα and co-treatments. Sci Rep. 2017;7:43541 pubmed publisher
  187. Hammers D, Merscham Banda M, Hsiao J, ENGST S, Hartman J, Sweeney H. Supraphysiological levels of GDF11 induce striated muscle atrophy. EMBO Mol Med. 2017;9:531-544 pubmed publisher
  188. Koenen A, Babendreyer A, Schumacher J, Pasqualon T, Schwarz N, Seifert A, et al. The DRF motif of CXCR6 as chemokine receptor adaptation to adhesion. PLoS ONE. 2017;12:e0173486 pubmed publisher
  189. Sato M, Kawana K, Adachi K, Fujimoto A, Yoshida M, Nakamura H, et al. Targeting glutamine metabolism and the focal adhesion kinase additively inhibits the mammalian target of the rapamycin pathway in spheroid cancer stem-like properties of ovarian clear cell carcinoma in vitro. Int J Oncol. 2017;50:1431-1438 pubmed publisher
  190. Li K, Mo C, Gong D, Chen Y, Huang Z, Li Y, et al. DDX17 nucleocytoplasmic shuttling promotes acquired gefitinib resistance in non-small cell lung cancer cells via activation of β-catenin. Cancer Lett. 2017;400:194-202 pubmed publisher
  191. Deying W, Feng G, Shumei L, Hui Z, Ming L, Hongqing W. CAF-derived HGF promotes cell proliferation and drug resistance by up-regulating the c-Met/PI3K/Akt and GRP78 signalling in ovarian cancer cells. Biosci Rep. 2017;37: pubmed publisher
  192. Obeid S, Wankell M, Charrez B, Sternberg J, Kreuter R, Esmaili S, et al. Adiponectin confers protection from acute colitis and restricts a B cell immune response. J Biol Chem. 2017;292:6569-6582 pubmed publisher
  193. Shi J, Bei Y, Kong X, Liu X, Lei Z, Xu T, et al. miR-17-3p Contributes to Exercise-Induced Cardiac Growth and Protects against Myocardial Ischemia-Reperfusion Injury. Theranostics. 2017;7:664-676 pubmed publisher
  194. Møller A, Kampmann U, Hedegaard J, Thorsen K, Nordentoft I, Vendelbo M, et al. Altered gene expression and repressed markers of autophagy in skeletal muscle of insulin resistant patients with type 2 diabetes. Sci Rep. 2017;7:43775 pubmed publisher
  195. Lal S, Cheung E, Zarei M, Preet R, Chand S, Mambelli Lisboa N, et al. CRISPR Knockout of the HuR Gene Causes a Xenograft Lethal Phenotype. Mol Cancer Res. 2017;15:696-707 pubmed publisher
  196. Hwang I, Park C, Harrison K, Kehrl J. Normal Thymocyte Egress, T Cell Trafficking, and CD4+ T Cell Homeostasis Require Interactions between RGS Proteins and Gαi2. J Immunol. 2017;198:2721-2734 pubmed publisher
  197. Pan X, Wang Y, Lübke T, Hinek A, Pshezhetsky A. Mice, double deficient in lysosomal serine carboxypeptidases Scpep1 and Cathepsin A develop the hyperproliferative vesicular corneal dystrophy and hypertrophic skin thickenings. PLoS ONE. 2017;12:e0172854 pubmed publisher
  198. Gueffier M, Zintz J, Lambert K, Finan A, Aimond F, Chakouri N, et al. The TRPM4 channel is functionally important for the beneficial cardiac remodeling induced by endurance training. J Muscle Res Cell Motil. 2017;38:3-16 pubmed publisher
  199. Sethna F, Feng W, Ding Q, ROBISON A, Feng Y, Wang H. Enhanced expression of ADCY1 underlies aberrant neuronal signalling and behaviour in a syndromic autism model. Nat Commun. 2017;8:14359 pubmed publisher
  200. Dong Q, Li J, Wu Q, Zhao N, Qian C, Ding D, et al. Blockage of transient receptor potential vanilloid 4 alleviates myocardial ischemia/reperfusion injury in mice. Sci Rep. 2017;7:42678 pubmed publisher
  201. Wang N, Yao F, Li K, Zhang L, Yin G, Du M, et al. Fisetin regulates astrocyte migration and proliferation in vitro. Int J Mol Med. 2017;39:783-790 pubmed publisher
  202. Peng M, Yin N, Li M. SZT2 dictates GATOR control of mTORC1 signalling. Nature. 2017;543:433-437 pubmed publisher
  203. Compagno M, Wang Q, Pighi C, Cheong T, Meng F, Poggio T, et al. Phosphatidylinositol 3-kinase δ blockade increases genomic instability in B cells. Nature. 2017;542:489-493 pubmed publisher
  204. Qian Q, Liu Q, Zhou D, Pan H, Liu Z, He F, et al. Brain-specific ablation of Efr3a promotes adult hippocampal neurogenesis via the brain-derived neurotrophic factor pathway. FASEB J. 2017;31:2104-2113 pubmed publisher
  205. Ganesan R, Hos N, Gutierrez S, Fischer J, Stepek J, Daglidu E, et al. Salmonella Typhimurium disrupts Sirt1/AMPK checkpoint control of mTOR to impair autophagy. PLoS Pathog. 2017;13:e1006227 pubmed publisher
  206. Xu W, Li B, Guan X, Chung S, Wang Y, Yip Y, et al. Cancer cell-secreted IGF2 instigates fibroblasts and bone marrow-derived vascular progenitor cells to promote cancer progression. Nat Commun. 2017;8:14399 pubmed publisher
  207. Yang G, Zhao Z, Qin T, Wang D, Chen L, Xiang R, et al. TNFSF15 inhibits VEGF-stimulated vascular hyperpermeability by inducing VEGFR2 dephosphorylation. FASEB J. 2017;31:2001-2012 pubmed publisher
  208. Qiao A, Jin X, Pang J, Moskophidis D, Mivechi N. The transcriptional regulator of the chaperone response HSF1 controls hepatic bioenergetics and protein homeostasis. J Cell Biol. 2017;216:723-741 pubmed publisher
  209. Dong Q, Fu L, Zhao Y, Tan S, Wang E. Derlin-1 overexpression confers poor prognosis in muscle invasive bladder cancer and contributes to chemoresistance and invasion through PI3K/AKT and ERK/MMP signaling. Oncotarget. 2017;8:17059-17069 pubmed publisher
  210. Zhu Y, Takayama T, Wang B, Kent A, Zhang M, Binder B, et al. Restenosis Inhibition and Re-differentiation of TGFβ/Smad3-activated Smooth Muscle Cells by Resveratrol. Sci Rep. 2017;7:41916 pubmed publisher
  211. Shen C, Zhou J, Wang X, Yu X, Liang C, Liu B, et al. Angiotensin-II-induced Muscle Wasting is Mediated by 25-Hydroxycholesterol via GSK3? Signaling Pathway. EBioMedicine. 2017;16:238-250 pubmed publisher
  212. Lim E, Nakanishi S, Hoghooghi V, Eaton S, Palmer A, Frederick A, et al. AlphaB-crystallin regulates remyelination after peripheral nerve injury. Proc Natl Acad Sci U S A. 2017;114:E1707-E1716 pubmed publisher
  213. Mindos T, Dun X, North K, Doddrell R, Schulz A, Edwards P, et al. Merlin controls the repair capacity of Schwann cells after injury by regulating Hippo/YAP activity. J Cell Biol. 2017;216:495-510 pubmed publisher
  214. Yang H, Ju F, Guo X, Ma S, Wang L, Cheng B, et al. RNA-binding protein RBM3 prevents NO-induced apoptosis in human neuroblastoma cells by modulating p38 signaling and miR-143. Sci Rep. 2017;7:41738 pubmed publisher
  215. Pergola C, Schubert K, Pace S, Ziereisen J, Nikels F, Scherer O, et al. Modulation of actin dynamics as potential macrophage subtype-targeting anti-tumour strategy. Sci Rep. 2017;7:41434 pubmed publisher
  216. Sugg K, Korn M, Sarver D, Markworth J, Mendias C. Inhibition of platelet-derived growth factor signaling prevents muscle fiber growth during skeletal muscle hypertrophy. FEBS Lett. 2017;591:801-809 pubmed publisher
  217. Kissing S, Rudnik S, Damme M, Lüllmann Rauch R, Ichihara A, Kornak U, et al. Disruption of the vacuolar-type H+-ATPase complex in liver causes MTORC1-independent accumulation of autophagic vacuoles and lysosomes. Autophagy. 2017;13:670-685 pubmed publisher
  218. Liu J, Wang H, Gu J, Deng T, Yuan Z, Hu B, et al. BECN1-dependent CASP2 incomplete autophagy induction by binding to rabies virus phosphoprotein. Autophagy. 2017;13:739-753 pubmed publisher
  219. Cederquist C, Lentucci C, Martinez Calejman C, Hayashi V, Orofino J, GUERTIN D, et al. Systemic insulin sensitivity is regulated by GPS2 inhibition of AKT ubiquitination and activation in adipose tissue. Mol Metab. 2017;6:125-137 pubmed publisher
  220. Chen B, Tan Y, Liang Y, Li Y, Chen L, Wu S, et al. Per2 participates in AKT-mediated drug resistance in A549/DDP lung adenocarcinoma cells. Oncol Lett. 2017;13:423-428 pubmed publisher
  221. Sheng L, Mao X, Yu Q, Yu D. Effect of the PI3K/AKT signaling pathway on hypoxia-induced proliferation and differentiation of bone marrow-derived mesenchymal stem cells. Exp Ther Med. 2017;13:55-62 pubmed publisher
  222. Villar V, Nguyen T, Delcroix V, Terés S, Bouchecareilh M, Salin B, et al. mTORC1 inhibition in cancer cells protects from glutaminolysis-mediated apoptosis during nutrient limitation. Nat Commun. 2017;8:14124 pubmed publisher
  223. Guo J, Kim N, Cui X. Inhibition of Fatty Acid Synthase Reduces Blastocyst Hatching through Regulation of the AKT Pathway in Pigs. PLoS ONE. 2017;12:e0170624 pubmed publisher
  224. Kanuri B, Kanshana J, Rebello S, Pathak P, Gupta A, Gayen J, et al. Altered glucose and lipid homeostasis in liver and adipose tissue pre-dispose inducible NOS knockout mice to insulin resistance. Sci Rep. 2017;7:41009 pubmed publisher
  225. Barcus C, O Leary K, Brockman J, Rugowski D, Liu Y, Garcia N, et al. Elevated collagen-I augments tumor progressive signals, intravasation and metastasis of prolactin-induced estrogen receptor alpha positive mammary tumor cells. Breast Cancer Res. 2017;19:9 pubmed publisher
  226. Ertsås H, Nolan G, Labarge M, Lorens J. Microsphere cytometry to interrogate microenvironment-dependent cell signaling. Integr Biol (Camb). 2017;9:123-134 pubmed publisher
  227. Yoo S, Latifkar A, Cerione R, Antonyak M. Cool-associated Tyrosine-phosphorylated Protein 1 Is Required for the Anchorage-independent Growth of Cervical Carcinoma Cells by Binding Paxillin and Promoting AKT Activation. J Biol Chem. 2017;292:3947-3957 pubmed publisher
  228. Chaudhari A, Gupta R, Patel S, Velingkaar N, Kondratov R. Cryptochromes regulate IGF-1 production and signaling through control of JAK2-dependent STAT5B phosphorylation. Mol Biol Cell. 2017;28:834-842 pubmed publisher
  229. Gross S, Rotwein P. Quantification of growth factor signaling and pathway cross talk by live-cell imaging. Am J Physiol Cell Physiol. 2017;312:C328-C340 pubmed publisher
  230. Cao H, Yu S, Chen D, Jing C, Wang Z, Ma R, et al. Liver X receptor agonist T0901317 reverses resistance of A549 human lung cancer cells to EGFR-TKI treatment. FEBS Open Bio. 2017;7:35-43 pubmed publisher
  231. Mescher M, Jeong P, Knapp S, Rübsam M, Saynisch M, Kranen M, et al. The epidermal polarity protein Par3 is a non-cell autonomous suppressor of malignant melanoma. J Exp Med. 2017;214:339-358 pubmed publisher
  232. Kechele D, Blue R, Zwarycz B, Espenschied S, Mah A, Siegel M, et al. Orphan Gpr182 suppresses ERK-mediated intestinal proliferation during regeneration and adenoma formation. J Clin Invest. 2017;127:593-607 pubmed publisher
  233. Kang Y, Balter B, Csizmadia E, Haas B, Sharma H, Bronson R, et al. Contribution of classical end-joining to PTEN inactivation in p53-mediated glioblastoma formation and drug-resistant survival. Nat Commun. 2017;8:14013 pubmed publisher
  234. Yue F, Bi P, Wang C, Shan T, Nie Y, Ratliff T, et al. Pten is necessary for the quiescence and maintenance of adult muscle stem cells. Nat Commun. 2017;8:14328 pubmed publisher
  235. Granato M, Rizzello C, Gilardini Montani M, Cuomo L, Vitillo M, Santarelli R, et al. Quercetin induces apoptosis and autophagy in primary effusion lymphoma cells by inhibiting PI3K/AKT/mTOR and STAT3 signaling pathways. J Nutr Biochem. 2017;41:124-136 pubmed publisher
  236. Worrall C, Suleymanova N, Crudden C, Trocoli Drakensjö I, Candrea E, Nedelcu D, et al. Unbalancing p53/Mdm2/IGF-1R axis by Mdm2 activation restrains the IGF-1-dependent invasive phenotype of skin melanoma. Oncogene. 2017;36:3274-3286 pubmed publisher
  237. Dror E, Dalmas E, Meier D, Wueest S, Thévenet J, Thienel C, et al. Postprandial macrophage-derived IL-1β stimulates insulin, and both synergistically promote glucose disposal and inflammation. Nat Immunol. 2017;18:283-292 pubmed publisher
  238. Merckx E, Albertini G, Paterka M, Jensen C, Albrecht P, Dietrich M, et al. Absence of system xc- on immune cells invading the central nervous system alleviates experimental autoimmune encephalitis. J Neuroinflammation. 2017;14:9 pubmed publisher
  239. Hussain R, Macklin W. Integrin-Linked Kinase (ILK) Deletion Disrupts Oligodendrocyte Development by Altering Cell Cycle. J Neurosci. 2017;37:397-412 pubmed publisher
  240. Huang S, Mao J, Ding K, Zhou Y, Zeng X, Yang W, et al. Polysaccharides from Ganoderma lucidum Promote Cognitive Function and Neural Progenitor Proliferation in Mouse Model of Alzheimer's Disease. Stem Cell Reports. 2017;8:84-94 pubmed publisher
  241. Decourtye L, Mire E, Clemessy M, Heurtier V, Ledent T, Robinson I, et al. IGF-1 Induces GHRH Neuronal Axon Elongation during Early Postnatal Life in Mice. PLoS ONE. 2017;12:e0170083 pubmed publisher
  242. Jiang C, Diao F, Sang Y, Xu N, Zhu R, Wang X, et al. GGPP-Mediated Protein Geranylgeranylation in Oocyte Is Essential for the Establishment of Oocyte-Granulosa Cell Communication and Primary-Secondary Follicle Transition in Mouse Ovary. PLoS Genet. 2017;13:e1006535 pubmed publisher
  243. Muranen T, Iwanicki M, Curry N, Hwang J, DuBois C, Coloff J, et al. Starved epithelial cells uptake extracellular matrix for survival. Nat Commun. 2017;8:13989 pubmed publisher
  244. Rahman A, Haugh J. Kinetic Modeling and Analysis of the Akt/Mechanistic Target of Rapamycin Complex 1 (mTORC1) Signaling Axis Reveals Cooperative, Feedforward Regulation. J Biol Chem. 2017;292:2866-2872 pubmed publisher
  245. Yamauchi T, Nishiyama M, Moroishi T, Kawamura A, Nakayama K. FBXL5 Inactivation in Mouse Brain Induces Aberrant Proliferation of Neural Stem Progenitor Cells. Mol Cell Biol. 2017;37: pubmed publisher
  246. Wu Q, Ma Y, Ruan C, Yang Y, Liu X, Ge Q, et al. Loss of osteoglycin promotes angiogenesis in limb ischaemia mouse models via modulation of vascular endothelial growth factor and vascular endothelial growth factor receptor 2 signalling pathway. Cardiovasc Res. 2017;113:70-80 pubmed publisher
  247. Zhao B, Hu W, Kumar S, Gonyo P, Rana U, Liu Z, et al. The Nogo-B receptor promotes Ras plasma membrane localization and activation. Oncogene. 2017;36:3406-3416 pubmed publisher
  248. Oller J, Méndez Barbero N, Ruiz E, Villahoz S, Renard M, Canelas L, et al. Nitric oxide mediates aortic disease in mice deficient in the metalloprotease Adamts1 and in a mouse model of Marfan syndrome. Nat Med. 2017;23:200-212 pubmed publisher
  249. Hirai M, Arita Y, McGlade C, Lee K, Chen J, Evans S. Adaptor proteins NUMB and NUMBL promote cell cycle withdrawal by targeting ERBB2 for degradation. J Clin Invest. 2017;127:569-582 pubmed publisher
  250. Hichino A, Okamoto M, Taga S, Akizuki R, Endo S, Matsunaga T, et al. Down-regulation of Claudin-2 Expression and Proliferation by Epigenetic Inhibitors in Human Lung Adenocarcinoma A549 Cells. J Biol Chem. 2017;292:2411-2421 pubmed publisher
  251. Hu N, Chang H, Du B, Zhang Q, Arfat Y, Dang K, et al. Tetramethylpyrazine ameliorated disuse-induced gastrocnemius muscle atrophy in hindlimb unloading rats through suppression of Ca2+/ROS-mediated apoptosis. Appl Physiol Nutr Metab. 2017;42:117-127 pubmed publisher
  252. Babagana M, Johnson S, Slabodkin H, Bshara W, Morrison C, Kandel E. P21-activated kinase 1 regulates resistance to BRAF inhibition in human cancer cells. Mol Carcinog. 2017;56:1515-1525 pubmed publisher
  253. Tam K, Dalal K, Hsing M, Cheng C, Khosravi S, Yenki P, et al. Androgen receptor transcriptionally regulates semaphorin 3C in a GATA2-dependent manner. Oncotarget. 2017;8:9617-9633 pubmed publisher
  254. Reynolds L, Dickens B, Green B, Marsit C, Pearson K. Using neonatal skin to study the developmental programming of aging. Exp Gerontol. 2017;94:93-98 pubmed publisher
  255. Krycer J, Fazakerley D, Cater R, C Thomas K, Naghiloo S, Burchfield J, et al. The amino acid transporter, SLC1A3, is plasma membrane-localised in adipocytes and its activity is insensitive to insulin. FEBS Lett. 2017;591:322-330 pubmed publisher
  256. Sivagurunathan S, Palanisamy K, Arunachalam J, Chidambaram S. Possible role of HIWI2 in modulating tight junction proteins in retinal pigment epithelial cells through Akt signaling pathway. Mol Cell Biochem. 2017;427:145-156 pubmed publisher
  257. Grossi M, Bhattachariya A, Nordström I, Turczynska K, Svensson D, Albinsson S, et al. Pyk2 inhibition promotes contractile differentiation in arterial smooth muscle. J Cell Physiol. 2017;232:3088-3102 pubmed publisher
  258. Hammers D, Sleeper M, Forbes S, Coker C, Jirousek M, Zimmer M, et al. Disease-modifying effects of orally bioavailable NF-κB inhibitors in dystrophin-deficient muscle. JCI Insight. 2016;1:e90341 pubmed publisher
  259. Hill S, Nesser N, Johnson Camacho K, Jeffress M, Johnson A, Boniface C, et al. Context Specificity in Causal Signaling Networks Revealed by Phosphoprotein Profiling. Cell Syst. 2017;4:73-83.e10 pubmed publisher
  260. Jin F, Jiang K, Ji S, Wang L, Ni Z, Huang F, et al. Deficient TSC1/TSC2-complex suppression of SOX9-osteopontin-AKT signalling cascade constrains tumour growth in tuberous sclerosis complex. Hum Mol Genet. 2017;26:407-419 pubmed publisher
  261. Ohtsuka T, Sakaguchi M, Yamamoto H, Tomida S, Takata K, Shien K, et al. Interaction of cytokeratin 19 head domain and HER2 in the cytoplasm leads to activation of HER2-Erk pathway. Sci Rep. 2016;6:39557 pubmed publisher
  262. Fourneaux B, Chaire V, Lucchesi C, Karanian M, Pineau R, Laroche Clary A, et al. Dual inhibition of the PI3K/AKT/mTOR pathway suppresses the growth of leiomyosarcomas but leads to ERK activation through mTORC2: biological and clinical implications. Oncotarget. 2017;8:7878-7890 pubmed publisher
  263. Vakana E, Pratt S, Blosser W, Dowless M, Simpson N, Yuan X, et al. LY3009120, a panRAF inhibitor, has significant anti-tumor activity in BRAF and KRAS mutant preclinical models of colorectal cancer. Oncotarget. 2017;8:9251-9266 pubmed publisher
  264. Li Y, Buijs Gladdines J, Canté Barrett K, Stubbs A, Vroegindeweij E, Smits W, et al. IL-7 Receptor Mutations and Steroid Resistance in Pediatric T cell Acute Lymphoblastic Leukemia: A Genome Sequencing Study. PLoS Med. 2016;13:e1002200 pubmed publisher
  265. Wymant J, Hiscox S, Westwell A, Urbé S, Clague M, Jones A. The Role of BCA2 in the Endocytic Trafficking of EGFR and Significance as a Prognostic Biomarker in Cancer. J Cancer. 2016;7:2388-2407 pubmed
  266. Yu Z, Mouillesseaux K, Kushner E, Bautch V. Tumor-Derived Factors and Reduced p53 Promote Endothelial Cell Centrosome Over-Duplication. PLoS ONE. 2016;11:e0168334 pubmed publisher
  267. Ganta V, Choi M, Kutateladze A, Annex B. VEGF165b Modulates Endothelial VEGFR1-STAT3 Signaling Pathway and Angiogenesis in Human and Experimental Peripheral Arterial Disease. Circ Res. 2017;120:282-295 pubmed publisher
  268. Yang J, Savvatis K, Kang J, Fan P, Zhong H, Schwartz K, et al. Targeting LOXL2 for cardiac interstitial fibrosis and heart failure treatment. Nat Commun. 2016;7:13710 pubmed publisher
  269. Zhang H, Wang W, Ren L, Zhao X, Wang Z, Zhuang D, et al. The mTORC2/Akt/NFκB Pathway-Mediated Activation of TRPC6 Participates in Adriamycin-Induced Podocyte Apoptosis. Cell Physiol Biochem. 2016;40:1079-1093 pubmed
  270. Hess N, Jiang S, Li X, Guan Y, Tapping R. TLR10 Is a B Cell Intrinsic Suppressor of Adaptive Immune Responses. J Immunol. 2017;198:699-707 pubmed publisher
  271. Karki R, Man S, Malireddi R, Kesavardhana S, Zhu Q, Burton A, et al. NLRC3 is an inhibitory sensor of PI3K-mTOR pathways in cancer. Nature. 2016;540:583-587 pubmed publisher
  272. Ramratnam M, Salama G, Sharma R, Wang D, Smith S, Banerjee S, et al. Gene-Targeted Mice with the Human Troponin T R141W Mutation Develop Dilated Cardiomyopathy with Calcium Desensitization. PLoS ONE. 2016;11:e0167681 pubmed publisher
  273. Mukhopadhyay C, Triplett A, Bargar T, HECKMAN C, Wagner K, Naramura M. Casitas B-cell lymphoma (Cbl) proteins protect mammary epithelial cells from proteotoxicity of active c-Src accumulation. Proc Natl Acad Sci U S A. 2016;113:E8228-E8237 pubmed publisher
  274. Tanouchi A, Taniuchi K, Furihata M, Naganuma S, Dabanaka K, Kimura M, et al. CCDC88A, a prognostic factor for human pancreatic cancers, promotes the motility and invasiveness of pancreatic cancer cells. J Exp Clin Cancer Res. 2016;35:190 pubmed
  275. Li J, Casteels T, Frogne T, Ingvorsen C, Honore C, Courtney M, et al. Artemisinins Target GABAA Receptor Signaling and Impair ? Cell Identity. Cell. 2017;168:86-100.e15 pubmed publisher
  276. Naeem A, Tommasi C, Cole C, Brown S, Zhu Y, Way B, et al. A mechanistic target of rapamycin complex 1/2 (mTORC1)/V-Akt murine thymoma viral oncogene homolog 1 (AKT1)/cathepsin H axis controls filaggrin expression and processing in skin, a novel mechanism for skin barrier disruption in patients with atopic d. J Allergy Clin Immunol. 2017;139:1228-1241 pubmed publisher
  277. Weyandt J, Carney J, Pavlisko E, Xu M, Counter C. Isoform-Specific Effects of Wild-Type Ras Genes on Carcinogen-Induced Lung Tumorigenesis in Mice. PLoS ONE. 2016;11:e0167205 pubmed publisher
  278. Yan H, Gao Y, Zhang Y. Inhibition of JNK suppresses autophagy and attenuates insulin resistance in a rat model of nonalcoholic fatty liver disease. Mol Med Rep. 2017;15:180-186 pubmed publisher
  279. Grabinski T, Kanaan N. Novel Non-phosphorylated Serine 9/21 GSK3?/? Antibodies: Expanding the Tools for Studying GSK3 Regulation. Front Mol Neurosci. 2016;9:123 pubmed
  280. Battram A, Durrant T, Agbani E, Heesom K, Paul D, Piatt R, et al. The Phosphatidylinositol 3,4,5-trisphosphate (PI(3,4,5)P3) Binder Rasa3 Regulates Phosphoinositide 3-kinase (PI3K)-dependent Integrin αIIbβ3 Outside-in Signaling. J Biol Chem. 2017;292:1691-1704 pubmed publisher
  281. Mueller A, van Velthoven C, Fukumoto K, Cheung T, Rando T. Intronic polyadenylation of PDGFR? in resident stem cells attenuates muscle fibrosis. Nature. 2016;540:276-279 pubmed publisher
  282. Torgersen M, Klokk T, Kavaliauskiene S, Klose C, Simons K, Skotland T, et al. The anti-tumor drug 2-hydroxyoleic acid (Minerval) stimulates signaling and retrograde transport. Oncotarget. 2016;7:86871-86888 pubmed publisher
  283. Liu W, Huang K, Lu M, Huang H, Chen C, Cheng Y, et al. TGF-β upregulates the translation of USP15 via the PI3K/AKT pathway to promote p53 stability. Oncogene. 2017;36:2715-2723 pubmed publisher
  284. Kariolis M, Miao Y, Diep A, Nash S, Olcina M, Jiang D, et al. Inhibition of the GAS6/AXL pathway augments the efficacy of chemotherapies. J Clin Invest. 2017;127:183-198 pubmed publisher
  285. Langhi C, Arias N, Rajamoorthi A, Basta J, Lee R, Baldán A. Therapeutic silencing of fat-specific protein 27 improves glycemic control in mouse models of obesity and insulin resistance. J Lipid Res. 2017;58:81-91 pubmed publisher
  286. Wang X, Cao Q, Yu L, Shi H, Xue B, Shi H. Epigenetic regulation of macrophage polarization and inflammation by DNA methylation in obesity. JCI Insight. 2016;1:e87748 pubmed publisher
  287. Pearson Leary J, McNay E. Novel Roles for the Insulin-Regulated Glucose Transporter-4 in Hippocampally Dependent Memory. J Neurosci. 2016;36:11851-11864 pubmed
  288. Reuther C, Heinzle V, Nölting S, Herterich S, Hahner S, Halilovic E, et al. The HDM2 (MDM2) Inhibitor NVP-CGM097 Inhibits Tumor Cell Proliferation and Shows Additive Effects with 5-Fluorouracil on the p53-p21-Rb-E2F1 Cascade in the p53wild type Neuroendocrine Tumor Cell Line GOT1. Neuroendocrinology. 2018;106:1-19 pubmed publisher
  289. Kim H, Kim M, Park Y, Park I, Kim T, Yang S, et al. Prostaglandin E2 Activates YAP and a Positive-Signaling Loop to Promote Colon Regeneration After Colitis but Also Carcinogenesis in Mice. Gastroenterology. 2017;152:616-630 pubmed publisher
  290. Shi D, Liu Y, Xi R, Zou W, Wu L, Zhang Z, et al. Caveolin-1 contributes to realgar nanoparticle therapy in human chronic myelogenous leukemia K562 cells. Int J Nanomedicine. 2016;11:5823-5835 pubmed
  291. Vidimar V, Gius D, Chakravarti D, Bulun S, Wei J, Kim J. Dysfunctional MnSOD leads to redox dysregulation and activation of prosurvival AKT signaling in uterine leiomyomas. Sci Adv. 2016;2:e1601132 pubmed
  292. Moyle L, Blanc E, Jaka O, Prueller J, Banerji C, Tedesco F, et al. Ret function in muscle stem cells points to tyrosine kinase inhibitor therapy for facioscapulohumeral muscular dystrophy. elife. 2016;5: pubmed publisher
  293. Kong Q, Zhang H, Zhao T, Zhang W, Yan M, Dong X, et al. Tangshen formula attenuates hepatic steatosis by inhibiting hepatic lipogenesis and augmenting fatty acid oxidation in db/db mice. Int J Mol Med. 2016;38:1715-1726 pubmed publisher
  294. Park J, Lee C, Kim H, Kim D, Son J, Ko E, et al. Suppression of the metastatic spread of breast cancer by DN10764 (AZD7762)-mediated inhibition of AXL signaling. Oncotarget. 2016;7:83308-83318 pubmed publisher
  295. Pandey R, Mehrotra S, Sharma S, Gudde R, Sundar S, Shaha C. Leishmania donovani-Induced Increase in Macrophage Bcl-2 Favors Parasite Survival. Front Immunol. 2016;7:456 pubmed
  296. Sikander M, Hafeez B, Malik S, Alsayari A, Halaweish F, Yallapu M, et al. Cucurbitacin D exhibits potent anti-cancer activity in cervical cancer. Sci Rep. 2016;6:36594 pubmed publisher
  297. Chruvattil R, Banerjee S, Nath S, Machhi J, Kharkwal G, Yadav M, et al. Dexamethasone Alters the Appetite Regulation via Induction of Hypothalamic Insulin Resistance in Rat Brain. Mol Neurobiol. 2017;54:7483-7496 pubmed publisher
  298. Han C, Juncadella I, Kinchen J, Buckley M, Klibanov A, Dryden K, et al. Macrophages redirect phagocytosis by non-professional phagocytes and influence inflammation. Nature. 2016;539:570-574 pubmed publisher
  299. Spencer Smith R, Koide A, Zhou Y, Eguchi R, Sha F, Gajwani P, et al. Inhibition of RAS function through targeting an allosteric regulatory site. Nat Chem Biol. 2017;13:62-68 pubmed publisher
  300. Cieniewicz A, Kirchner T, Hinke S, Nanjunda R, D AQUINO K, Boayke K, et al. Novel Monoclonal Antibody Is an Allosteric Insulin Receptor Antagonist That Induces Insulin Resistance. Diabetes. 2017;66:206-217 pubmed publisher
  301. Sheen M, Marotti J, Allegrezza M, Rutkowski M, Conejo Garcia J, Fiering S. Constitutively activated PI3K accelerates tumor initiation and modifies histopathology of breast cancer. Oncogenesis. 2016;5:e267 pubmed publisher
  302. Wang S, Chennupati R, Kaur H, Iring A, Wettschureck N, Offermanns S. Endothelial cation channel PIEZO1 controls blood pressure by mediating flow-induced ATP release. J Clin Invest. 2016;126:4527-4536 pubmed publisher
  303. Fan Y, Wang N, Rocchi A, Zhang W, Vassar R, Zhou Y, et al. Identification of natural products with neuronal and metabolic benefits through autophagy induction. Autophagy. 2017;13:41-56 pubmed publisher
  304. Alekhina O, Marchese A. ?-Arrestin1 and Signal-transducing Adaptor Molecule 1 (STAM1) Cooperate to Promote Focal Adhesion Kinase Autophosphorylation and Chemotaxis via the Chemokine Receptor CXCR4. J Biol Chem. 2016;291:26083-26097 pubmed
  305. Li R, Xu J, Fu C, Zhang J, Zheng Y, Jia H, et al. Regulation of mTORC1 by lysosomal calcium and calmodulin. elife. 2016;5: pubmed publisher
  306. Hau A, Leivo M, Gilder A, Hu J, Gonias S, Hansel D. mTORC2 activation is regulated by the urokinase receptor (uPAR) in bladder cancer. Cell Signal. 2017;29:96-106 pubmed publisher
  307. Goebbels S, Wieser G, Pieper A, Spitzer S, Weege B, Yan K, et al. A neuronal PI(3,4,5)P3-dependent program of oligodendrocyte precursor recruitment and myelination. Nat Neurosci. 2017;20:10-15 pubmed publisher
  308. Zhao J, Chen C, Guo M, Tao Y, Cui P, Zhou Y, et al. MicroRNA-7 Deficiency Ameliorates the Pathologies of Acute Lung Injury through Elevating KLF4. Front Immunol. 2016;7:389 pubmed
  309. Di Cataldo V, Geloen A, Langlois J, Chauveau F, Thézé B, Hubert V, et al. Exercise Does Not Protect against Peripheral and Central Effects of a High Cholesterol Diet Given Ad libitum in Old ApoE-/- Mice. Front Physiol. 2016;7:453 pubmed
  310. Zhang Q, Zhang Y, Parsels J, Lohse I, Lawrence T, Pasca di Magliano M, et al. Fbxw7 Deletion Accelerates KrasG12D-Driven Pancreatic Tumorigenesis via Yap Accumulation. Neoplasia. 2016;18:666-673 pubmed publisher
  311. Che D, Zhou T, Lan Y, Xie J, Gong H, Li C, et al. High glucose-induced epithelial-mesenchymal transition contributes to the upregulation of fibrogenic factors in retinal pigment epithelial cells. Int J Mol Med. 2016;38:1815-1822 pubmed publisher
  312. Sanchez T, Zhang G, Li J, Dai L, Mirshahidi S, Wall N, et al. Immunoseroproteomic Profiling in African American Men with Prostate Cancer: Evidence for an Autoantibody Response to Glycolysis and Plasminogen-Associated Proteins. Mol Cell Proteomics. 2016;15:3564-3580 pubmed
  313. Hinds T, Burns K, Hosick P, McBeth L, Nestor Kalinoski A, Drummond H, et al. Biliverdin Reductase A Attenuates Hepatic Steatosis by Inhibition of Glycogen Synthase Kinase (GSK) 3? Phosphorylation of Serine 73 of Peroxisome Proliferator-activated Receptor (PPAR) ?. J Biol Chem. 2016;291:25179-25191 pubmed
  314. Kimura T, Nada S, Takegahara N, Okuno T, Nojima S, Kang S, et al. Polarization of M2 macrophages requires Lamtor1 that integrates cytokine and amino-acid signals. Nat Commun. 2016;7:13130 pubmed publisher
  315. Southworth T, Plumb J, Gupta V, Pearson J, Ramis I, Lehner M, et al. Anti-inflammatory potential of PI3K? and JAK inhibitors in asthma patients. Respir Res. 2016;17:124 pubmed
  316. Kubota N, Kubota T, Kajiwara E, Iwamura T, Kumagai H, Watanabe T, et al. Differential hepatic distribution of insulin receptor substrates causes selective insulin resistance in diabetes and obesity. Nat Commun. 2016;7:12977 pubmed publisher
  317. Beauvais G, Bode N, Watson J, Wen H, Glenn K, Kawano H, et al. Disruption of Protein Processing in the Endoplasmic Reticulum of DYT1 Knock-in Mice Implicates Novel Pathways in Dystonia Pathogenesis. J Neurosci. 2016;36:10245-10256 pubmed
  318. Rodina A, Wang T, Yan P, Gomes E, Dunphy M, Pillarsetty N, et al. The epichaperome is an integrated chaperome network that facilitates tumour survival. Nature. 2016;538:397-401 pubmed publisher
  319. Yong K, Li A, Ou W, Hong C, Zhao W, Wang F, et al. Targeting SALL4 by entinostat in lung cancer. Oncotarget. 2016;7:75425-75440 pubmed publisher
  320. Cizmecioglu O, Ni J, Xie S, Zhao J, Roberts T. Rac1-mediated membrane raft localization of PI3K/p110? is required for its activation by GPCRs or PTEN loss. elife. 2016;5: pubmed publisher
  321. Nonomiya Y, Noguchi K, Tanaka N, Kasagaki T, Katayama K, Sugimoto Y. Effect of AKT3 expression on MYC- and caspase-8-dependent apoptosis caused by polo-like kinase inhibitors in HCT 116 cells. Cancer Sci. 2016;107:1877-1887 pubmed publisher
  322. Gerriets V, Kishton R, Johnson M, Cohen S, Siska P, Nichols A, et al. Foxp3 and Toll-like receptor signaling balance Treg cell anabolic metabolism for suppression. Nat Immunol. 2016;17:1459-1466 pubmed publisher
  323. Broix L, Jagline H, Ivanova E, Schmucker S, Drouot N, Clayton Smith J, et al. Mutations in the HECT domain of NEDD4L lead to AKT-mTOR pathway deregulation and cause periventricular nodular heterotopia. Nat Genet. 2016;48:1349-1358 pubmed publisher
  324. Little A, Sham D, Hristova M, Danyal K, Heppner D, Bauer R, et al. DUOX1 silencing in lung cancer promotes EMT, cancer stem cell characteristics and invasive properties. Oncogenesis. 2016;5:e261 pubmed publisher
  325. Patel S, Trivedi G, Darie C, Clarkson B. The possible roles of B-cell novel protein-1 (BCNP1) in cellular signalling pathways and in cancer. J Cell Mol Med. 2017;21:456-466 pubmed publisher
  326. Wei R, Lin S, Wu W, Chen L, Li C, Chen H, et al. A microtubule inhibitor, ABT-751, induces autophagy and delays apoptosis in Huh-7 cells. Toxicol Appl Pharmacol. 2016;311:88-98 pubmed publisher
  327. Vallo S, Michaelis M, Gust K, Black P, Rothweiler F, Kvasnicka H, et al. Dasatinib enhances tumor growth in gemcitabine-resistant orthotopic bladder cancer xenografts. BMC Res Notes. 2016;9:454 pubmed
  328. Yuzugullu H, Von T, Thorpe L, Walker S, Roberts T, Frank D, et al. NTRK2 activation cooperates with PTEN deficiency in T-ALL through activation of both the PI3K-AKT and JAK-STAT3 pathways. Cell Discov. 2016;2:16030 pubmed publisher
  329. Ang Z, Er J, Tan N, Lu J, Liou Y, Grosse J, et al. Human and mouse monocytes display distinct signalling and cytokine profiles upon stimulation with FFAR2/FFAR3 short-chain fatty acid receptor agonists. Sci Rep. 2016;6:34145 pubmed publisher
  330. Boo H, Min H, Jang H, Yun H, Smith J, Jin Q, et al. The tobacco-specific carcinogen-operated calcium channel promotes lung tumorigenesis via IGF2 exocytosis in lung epithelial cells. Nat Commun. 2016;7:12961 pubmed publisher
  331. Yang Z, Tsuchiya H, Zhang Y, Lee S, Liu C, Huang Y, et al. REV-ERB? Activates C/EBP Homologous Protein to Control Small Heterodimer Partner-Mediated Oscillation of Alcoholic Fatty Liver. Am J Pathol. 2016;186:2909-2920 pubmed publisher
  332. Cao R, Meng Z, Liu T, Wang G, Qian G, Cao T, et al. Decreased TRPM7 inhibits activities and induces apoptosis of bladder cancer cells via ERK1/2 pathway. Oncotarget. 2016;7:72941-72960 pubmed publisher
  333. Wang A, Cui M, Qu H, Di J, Wang Z, Xing J, et al. Induction of anti-EGFR immune response with mimotopes identified from a phage display peptide library by panitumumab. Oncotarget. 2016;7:75293-75306 pubmed publisher
  334. Shamblott M, O Driscoll M, Gomez D, McGuire D. Neurogenin 3 is regulated by neurotrophic tyrosine kinase receptor type 2 (TRKB) signaling in the adult human exocrine pancreas. Cell Commun Signal. 2016;14:23 pubmed
  335. Krepler C, Xiao M, Samanta M, Vultur A, Chen H, Brafford P, et al. Targeting Notch enhances the efficacy of ERK inhibitors in BRAF-V600E melanoma. Oncotarget. 2016;7:71211-71222 pubmed publisher
  336. Jansson D, Scotter E, Rustenhoven J, Coppieters N, Smyth L, Oldfield R, et al. Interferon-? blocks signalling through PDGFR? in human brain pericytes. J Neuroinflammation. 2016;13:249 pubmed
  337. Johnson R, Finger E, Olcina M, Vilalta M, Aguilera T, Miao Y, et al. Induction of LIFR confers a dormancy phenotype in breast cancer cells disseminated to the bone marrow. Nat Cell Biol. 2016;18:1078-1089 pubmed publisher
  338. Mercado Pimentel M, Igarashi S, Dunn A, Behbahani M, Miller C, Read C, et al. The Novel Small Molecule Inhibitor, OSU-T315, Suppresses Vestibular Schwannoma and Meningioma Growth by Inhibiting PDK2 Function in the AKT Pathway Activation. Austin J Med Oncol. 2016;3: pubmed
  339. Hang Q, Isaji T, Hou S, Zhou Y, Fukuda T, Gu J. N-Glycosylation of integrin ?5 acts as a switch for EGFR-mediated complex formation of integrin ?5?1 to ?6?4. Sci Rep. 2016;6:33507 pubmed publisher
  340. Christensen B, Nellemann B, Jørgensen J, Pedersen S, Jessen N. Erythropoietin does not activate erythropoietin receptor signaling or lipolytic pathways in human subcutaneous white adipose tissue in vivo. Lipids Health Dis. 2016;15:160 pubmed publisher
  341. Nip H, Dar A, Saini S, Colden M, Varahram S, Chowdhary H, et al. Oncogenic microRNA-4534 regulates PTEN pathway in prostate cancer. Oncotarget. 2016;7:68371-68384 pubmed publisher
  342. Rittig N, Bach E, Thomsen H, Pedersen S, Nielsen T, Jørgensen J, et al. Regulation of Lipolysis and Adipose Tissue Signaling during Acute Endotoxin-Induced Inflammation: A Human Randomized Crossover Trial. PLoS ONE. 2016;11:e0162167 pubmed publisher
  343. Carbonneau M, M Gagné L, Lalonde M, Germain M, Motorina A, Guiot M, et al. The oncometabolite 2-hydroxyglutarate activates the mTOR signalling pathway. Nat Commun. 2016;7:12700 pubmed publisher
  344. Shin M, Male I, Beane T, Villefranc J, Kok F, Zhu L, et al. Vegfc acts through ERK to induce sprouting and differentiation of trunk lymphatic progenitors. Development. 2016;143:3785-3795 pubmed
  345. Wu Y, Ren D, Chen G. Siglec-E Negatively Regulates the Activation of TLR4 by Controlling Its Endocytosis. J Immunol. 2016;197:3336-3347 pubmed
  346. Fan L, Liu M, Guo M, Hu C, Yan Z, Chen J, et al. FAM122A, a new endogenous inhibitor of protein phosphatase 2A. Oncotarget. 2016;7:63887-63900 pubmed publisher
  347. Phatak N, Stankowska D, Krishnamoorthy R. Bcl-2, Bcl-xL, and p-AKT are involved in neuroprotective effects of transcription factor Brn3b in an ocular hypertension rat model of glaucoma. Mol Vis. 2016;22:1048-61 pubmed
  348. Caporali S, Alvino E, Lacal P, Levati L, Giurato G, Memoli D, et al. Targeting the PI3K/AKT/mTOR pathway overcomes the stimulating effect of dabrafenib on the invasive behavior of melanoma cells with acquired resistance to the BRAF inhibitor. Int J Oncol. 2016;49:1164-74 pubmed publisher
  349. Josowitz R, Mulero Navarro S, Rodriguez N, Falce C, Cohen N, Ullian E, et al. Autonomous and Non-autonomous Defects Underlie Hypertrophic Cardiomyopathy in BRAF-Mutant hiPSC-Derived Cardiomyocytes. Stem Cell Reports. 2016;7:355-369 pubmed publisher
  350. Woodall B, Woodall M, Luongo T, Grisanti L, Tilley D, Elrod J, et al. Skeletal Muscle-specific G Protein-coupled Receptor Kinase 2 Ablation Alters Isolated Skeletal Muscle Mechanics and Enhances Clenbuterol-stimulated Hypertrophy. J Biol Chem. 2016;291:21913-21924 pubmed
  351. Hong X, Liu W, Song R, Shah J, Feng X, Tsang C, et al. SOX9 is targeted for proteasomal degradation by the E3 ligase FBW7 in response to DNA damage. Nucleic Acids Res. 2016;44:8855-8869 pubmed
  352. Padhan N, Nordling T, Sundstrom M, Akerud P, Birgisson H, Nygren P, et al. High sensitivity isoelectric focusing to establish a signaling biomarker for the diagnosis of human colorectal cancer. BMC Cancer. 2016;16:683 pubmed publisher
  353. Sun M, Cai J, Anderson R, Sun Y. Type I ? Phosphatidylinositol Phosphate 5-Kinase i5 Controls the Ubiquitination and Degradation of the Tumor Suppressor Mitogen-inducible Gene 6. J Biol Chem. 2016;291:21461-21473 pubmed
  354. Cunningham C, Li S, Vizeacoumar F, Bhanumathy K, Lee J, Parameswaran S, et al. Therapeutic relevance of the protein phosphatase 2A in cancer. Oncotarget. 2016;7:61544-61561 pubmed publisher
  355. Vermeij W, Dollé M, Reiling E, Jaarsma D, Payan Gomez C, Bombardieri C, et al. Restricted diet delays accelerated ageing and genomic stress in DNA-repair-deficient mice. Nature. 2016;537:427-431 pubmed publisher
  356. Lee J, Lee W, Seol M, Lee S, Kim D, Kim H, et al. Coupling of LETM1 up-regulation with oxidative phosphorylation and platelet-derived growth factor receptor signaling via YAP1 transactivation. Oncotarget. 2016;7:66728-66739 pubmed publisher
  357. Greenwood E, Maisel S, Ebertz D, Russ A, Pandey R, SCHROEDER J. Llgl1 prevents metaplastic survival driven by epidermal growth factor dependent migration. Oncotarget. 2016;7:60776-60792 pubmed publisher
  358. Szewczyk L, Brozko N, Nagalski A, Röckle I, Werneburg S, Hildebrandt H, et al. ST8SIA2 promotes oligodendrocyte differentiation and the integrity of myelin and axons. Glia. 2017;65:34-49 pubmed publisher
  359. Efazat G, Novak M, Kaminskyy V, De Petris L, Kanter L, Juntti T, et al. Ephrin B3 interacts with multiple EphA receptors and drives migration and invasion in non-small cell lung cancer. Oncotarget. 2016;7:60332-60347 pubmed publisher
  360. Beale G, Haagensen E, Thomas H, Wang L, Revill C, Payne S, et al. Combined PI3K and CDK2 inhibition induces cell death and enhances in vivo antitumour activity in colorectal cancer. Br J Cancer. 2016;115:682-90 pubmed publisher
  361. Chen R, Duan J, Li L, Ma Q, Sun Q, Ma J, et al. mTOR promotes pituitary tumor development through activation of PTTG1. Oncogene. 2017;36:979-988 pubmed publisher
  362. Ratsimandresy R, Indramohan M, Dorfleutner A, Stehlik C. The AIM2 inflammasome is a central regulator of intestinal homeostasis through the IL-18/IL-22/STAT3 pathway. Cell Mol Immunol. 2017;14:127-142 pubmed publisher
  363. Wang D, Mitchell E. Cognition and Synaptic-Plasticity Related Changes in Aged Rats Supplemented with 8- and 10-Carbon Medium Chain Triglycerides. PLoS ONE. 2016;11:e0160159 pubmed publisher
  364. Maynard J, Emmas S, Blé F, Barjat H, Lawrie E, Hancox U, et al. The use of (18)F-fluorodeoxyglucose positron emission tomography ((18)F-FDG PET) as a pathway-specific biomarker with AZD8186, a PI3K?/? inhibitor. EJNMMI Res. 2016;6:62 pubmed publisher
  365. Yang J, Song T, Jo C, Park J, Lee H, Song I, et al. Differential regulation of the histone chaperone HIRA during muscle cell differentiation by a phosphorylation switch. Exp Mol Med. 2016;48:e252 pubmed publisher
  366. Buta C, Benabou E, Lequoy M, Régnault H, Wendum D, Meratbene F, et al. Heregulin-1ß and HER3 in hepatocellular carcinoma: status and regulation by insulin. J Exp Clin Cancer Res. 2016;35:126 pubmed publisher
  367. Nadeau Vallée M, Boudreault A, Leimert K, Hou X, Obari D, Madaan A, et al. Uterotonic Neuromedin U Receptor 2 and Its Ligands Are Upregulated by Inflammation in Mice and Humans, and Elicit Preterm Birth. Biol Reprod. 2016;95:72 pubmed
  368. Ogasawara R, Fujita S, Hornberger T, Kitaoka Y, Makanae Y, Nakazato K, et al. The role of mTOR signalling in the regulation of skeletal muscle mass in a rodent model of resistance exercise. Sci Rep. 2016;6:31142 pubmed publisher
  369. Tsai S, Rodriguez A, Dastidar S, Del Greco E, Carr K, Sitzmann J, et al. Increased 4E-BP1 Expression Protects against Diet-Induced Obesity and Insulin Resistance in Male Mice. Cell Rep. 2016;16:1903-14 pubmed publisher
  370. Oh B, Kim S, Lee Y, Hong H, Kim T, Kim S, et al. Twist1-induced epithelial-mesenchymal transition according to microsatellite instability status in colon cancer cells. Oncotarget. 2016;7:57066-57076 pubmed publisher
  371. Di Franco S, Turdo A, Benfante A, Colorito M, Gaggianesi M, Apuzzo T, et al. ?Np63 drives metastasis in breast cancer cells via PI3K/CD44v6 axis. Oncotarget. 2016;7:54157-54173 pubmed publisher
  372. Xi R, Pan S, Chen X, Hui B, Zhang L, Fu S, et al. HPV16 E6-E7 induces cancer stem-like cells phenotypes in esophageal squamous cell carcinoma through the activation of PI3K/Akt signaling pathway in vitro and in vivo. Oncotarget. 2016;7:57050-57065 pubmed publisher
  373. Kawamoto E, Koshinaka K, Yoshimura T, Masuda H, Kawanaka K. Immobilization rapidly induces muscle insulin resistance together with the activation of MAPKs (JNK and p38) and impairment of AS160 phosphorylation. Physiol Rep. 2016;4: pubmed publisher
  374. Fiedor E, Gregoraszczuk E. The molecular mechanism of action of superactive human leptin antagonist (SHLA) and quadruple leptin mutein Lan-2 on human ovarian epithelial cell lines. Cancer Chemother Pharmacol. 2016;78:611-22 pubmed publisher
  375. Reginensi A, Enderle L, Gregorieff A, Johnson R, Wrana J, McNeill H. A critical role for NF2 and the Hippo pathway in branching morphogenesis. Nat Commun. 2016;7:12309 pubmed publisher
  376. Ladd B, Mazzola A, Bihani T, Lai Z, BRADFORD J, Collins M, et al. Effective combination therapies in preclinical endocrine resistant breast cancer models harboring ER mutations. Oncotarget. 2016;7:54120-54136 pubmed publisher
  377. Wang Y, Wang Y, Li G. TRPC1/TRPC3 channels mediate lysophosphatidylcholine-induced apoptosis in cultured human coronary artery smooth muscles cells. Oncotarget. 2016;7:50937-50951 pubmed publisher
  378. Franzese O, Palermo B, Di Donna C, Sperduti I, Ferraresi V, Stabile H, et al. Polyfunctional Melan-A-specific tumor-reactive CD8(+) T cells elicited by dacarbazine treatment before peptide-vaccination depends on AKT activation sustained by ICOS. Oncoimmunology. 2016;5:e1114203 pubmed publisher
  379. Bai Y, Dong Z, Shang Q, Zhao H, Wang L, Guo C, et al. Pdcd4 Is Involved in the Formation of Stress Granule in Response to Oxidized Low-Density Lipoprotein or High-Fat Diet. PLoS ONE. 2016;11:e0159568 pubmed publisher
  380. Fang F, Qin Y, Hao F, Li Q, Zhang W, Zhao C, et al. CD147 modulates androgen receptor activity through the Akt/Gsk-3?/?-catenin/AR pathway in prostate cancer cells. Oncol Lett. 2016;12:1124-1128 pubmed
  381. Bao H, Liu P, Jiang K, Zhang X, Xie L, Wang Z, et al. Huaier polysaccharide induces apoptosis in hepatocellular carcinoma cells through p38 MAPK. Oncol Lett. 2016;12:1058-1066 pubmed
  382. Lazzarini E, Balbi C, Altieri P, Pfeffer U, Gambini E, Canepa M, et al. The human amniotic fluid stem cell secretome effectively counteracts doxorubicin-induced cardiotoxicity. Sci Rep. 2016;6:29994 pubmed publisher
  383. Metz H, Kargl J, Busch S, Kim K, Kurland B, Abberbock S, et al. Insulin receptor substrate-1 deficiency drives a proinflammatory phenotype in KRAS mutant lung adenocarcinoma. Proc Natl Acad Sci U S A. 2016;113:8795-800 pubmed publisher
  384. Saisana M, Griffin S, May F. Importance of the type I insulin-like growth factor receptor in HER2, FGFR2 and MET-unamplified gastric cancer with and without Ras pathway activation. Oncotarget. 2016;7:54445-54462 pubmed publisher
  385. Diez H, Benitez M, Fernandez S, Torres Aleman I, Garrido J, Wandosell F. Class I PI3-kinase or Akt inhibition do not impair axonal polarization, but slow down axonal elongation. Biochim Biophys Acta. 2016;1863:2574-2583 pubmed publisher
  386. Ge X, Huang S, Gao H, Han Z, Chen F, Zhang S, et al. miR-21-5p alleviates leakage of injured brain microvascular endothelial barrier in vitro through suppressing inflammation and apoptosis. Brain Res. 2016;1650:31-40 pubmed publisher
  387. Song M, Wang Y, Shang Z, Liu X, Xie D, Wang Q, et al. Bystander autophagy mediated by radiation-induced exosomal miR-7-5p in non-targeted human bronchial epithelial cells. Sci Rep. 2016;6:30165 pubmed publisher
  388. Ma T, Fan B, Zhang C, Zhao H, Han C, Gao C, et al. Metabonomics applied in exploring the antitumour mechanism of physapubenolide on hepatocellular carcinoma cells by targeting glycolysis through the Akt-p53 pathway. Sci Rep. 2016;6:29926 pubmed publisher
  389. Jang H, Lee G, Selby C, Lee G, Jeon Y, Lee J, et al. SREBP1c-CRY1 signalling represses hepatic glucose production by promoting FOXO1 degradation during refeeding. Nat Commun. 2016;7:12180 pubmed publisher
  390. McClelland Descalzo D, Satoorian T, Walker L, Sparks N, Pulyanina P, zur Nieden N. Glucose-Induced Oxidative Stress Reduces Proliferation in Embryonic Stem Cells via FOXO3A/?-Catenin-Dependent Transcription of p21(cip1). Stem Cell Reports. 2016;7:55-68 pubmed publisher
  391. Warner M, Bridge K, Hewitson J, Hodgkinson M, Heyam A, Massa B, et al. S6K2-mediated regulation of TRBP as a determinant of miRNA expression in human primary lymphatic endothelial cells. Nucleic Acids Res. 2016;44:9942-9955 pubmed
  392. Zhang Y, Velez Delgado A, Mathew E, Li D, Mendez F, Flannagan K, et al. Myeloid cells are required for PD-1/PD-L1 checkpoint activation and the establishment of an immunosuppressive environment in pancreatic cancer. Gut. 2017;66:124-136 pubmed publisher
  393. Deblois G, Smith H, Tam I, Gravel S, Caron M, Savage P, et al. ERR? mediates metabolic adaptations driving lapatinib resistance in breast cancer. Nat Commun. 2016;7:12156 pubmed publisher
  394. Kumari M, Wang X, Lantier L, Lyubetskaya A, Eguchi J, Kang S, et al. IRF3 promotes adipose inflammation and insulin resistance and represses browning. J Clin Invest. 2016;126:2839-54 pubmed publisher
  395. Grassi M, Palma C, Thomé C, Lanfredi G, Poersch A, Faça V. Proteomic analysis of ovarian cancer cells during epithelial-mesenchymal transition (EMT) induced by epidermal growth factor (EGF) reveals mechanisms of cell cycle control. J Proteomics. 2017;151:2-11 pubmed publisher
  396. Eid S, Boutary S, Braych K, Sabra R, Massaad C, Hamdy A, et al. mTORC2 Signaling Regulates Nox4-Induced Podocyte Depletion in Diabetes. Antioxid Redox Signal. 2016;25:703-719 pubmed
  397. Zhou Y, Wu Y, Qin Y, Liu L, Wan J, Zou L, et al. Ampelopsin Improves Insulin Resistance by Activating PPAR? and Subsequently Up-Regulating FGF21-AMPK Signaling Pathway. PLoS ONE. 2016;11:e0159191 pubmed publisher
  398. Alver T, Lavelle T, Longva A, Øy G, Hovig E, Bøe S. MITF depletion elevates expression levels of ERBB3 receptor and its cognate ligand NRG1-beta in melanoma. Oncotarget. 2016;7:55128-55140 pubmed publisher
  399. Wang C, Guo S, Wang J, Yan X, Farrelly M, Zhang Y, et al. Reactivation of ERK and Akt confers resistance of mutant BRAF colon cancer cells to the HSP90 inhibitor AUY922. Oncotarget. 2016;7:49597-49610 pubmed publisher
  400. Huang C, Lee C, Lin H, Chang J. Cathepsin S attenuates endosomal EGFR signalling: A mechanical rationale for the combination of cathepsin S and EGFR tyrosine kinase inhibitors. Sci Rep. 2016;6:29256 pubmed publisher
  401. Shen P, Chen M, He M, Chen L, Song Y, Xiao P, et al. Inhibition of ER?/ERK/P62 cascades induces "autophagic switch" in the estrogen receptor-positive breast cancer cells exposed to gemcitabine. Oncotarget. 2016;7:48501-48516 pubmed publisher
  402. Li X, Chen Y, Wang L, Shang G, Zhang C, Zhao Z, et al. Quercetin alleviates pulmonary angiogenesis in a rat model of hepatopulmonary syndrome. Braz J Med Biol Res. 2016;49: pubmed publisher
  403. Rozo M, Li L, Fan C. Targeting ?1-integrin signaling enhances regeneration in aged and dystrophic muscle in mice. Nat Med. 2016;22:889-96 pubmed publisher
  404. Hatem R, El Botty R, Chateau Joubert S, Servely J, Labiod D, de Plater L, et al. Targeting mTOR pathway inhibits tumor growth in different molecular subtypes of triple-negative breast cancers. Oncotarget. 2016;7:48206-48219 pubmed publisher
  405. Xiao B, Chen D, Luo S, Hao W, Jing F, Liu T, et al. Extracellular translationally controlled tumor protein promotes colorectal cancer invasion and metastasis through Cdc42/JNK/ MMP9 signaling. Oncotarget. 2016;7:50057-50073 pubmed publisher
  406. Petrova L, Gran C, Bjoras M, Doetsch P. Efficient and Reliable Production of Vectors for the Study of the Repair, Mutagenesis, and Phenotypic Consequences of Defined DNA Damage Lesions in Mammalian Cells. PLoS ONE. 2016;11:e0158581 pubmed publisher
  407. Chen Y, LaMarche M, Chan H, Fekkes P, García Fortanet J, Acker M, et al. Allosteric inhibition of SHP2 phosphatase inhibits cancers driven by receptor tyrosine kinases. Nature. 2016;535:148-52 pubmed
  408. Su Q, Zhang B, Zhang L, Dang T, Rowley D, Ittmann M, et al. Jagged1 upregulation in prostate epithelial cells promotes formation of reactive stroma in the Pten null mouse model for prostate cancer. Oncogene. 2017;36:618-627 pubmed publisher
  409. Schmitt D, Funk N, Blum R, Asan E, Andersen L, Rülicke T, et al. Initial characterization of a Syap1 knock-out mouse and distribution of Syap1 in mouse brain and cultured motoneurons. Histochem Cell Biol. 2016;146:489-512 pubmed publisher
  410. Herring A, Münster Y, Akkaya T, Moghaddam S, Deinsberger K, Meyer J, et al. Kallikrein-8 inhibition attenuates Alzheimer's disease pathology in mice. Alzheimers Dement. 2016;12:1273-1287 pubmed publisher
  411. Chakedis J, French R, Babicky M, Jaquish D, Mose E, Cheng P, et al. Characterization of RON protein isoforms in pancreatic cancer: implications for biology and therapeutics. Oncotarget. 2016;7:45959-45975 pubmed publisher
  412. Gautheron J, Vucur M, Schneider A, Severi I, Roderburg C, Roy S, et al. The necroptosis-inducing kinase RIPK3 dampens adipose tissue inflammation and glucose intolerance. Nat Commun. 2016;7:11869 pubmed publisher
  413. Kemper K, Krijgsman O, Kong X, Cornelissen Steijger P, Shahrabi A, Weeber F, et al. BRAF(V600E) Kinase Domain Duplication Identified in Therapy-Refractory Melanoma Patient-Derived Xenografts. Cell Rep. 2016;16:263-277 pubmed publisher
  414. Wang Y, Hersheson J, López D, Hammer M, Liu Y, Lee K, et al. Defects in the CAPN1 Gene Result in Alterations in Cerebellar Development and Cerebellar Ataxia in Mice and Humans. Cell Rep. 2016;16:79-91 pubmed publisher
  415. Meinhardt G, Saleh L, Otti G, Haider S, Velicky P, Fiala C, et al. Wingless ligand 5a is a critical regulator of placental growth and survival. Sci Rep. 2016;6:28127 pubmed publisher
  416. Liu C, Lin S, Hsu H, Yang S, Lin C, Yang M, et al. Suspension survival mediated by PP2A-STAT3-Col XVII determines tumour initiation and metastasis in cancer stem cells. Nat Commun. 2016;7:11798 pubmed publisher
  417. Tisza M, Zhao W, Fuentes J, Prijic S, Chen X, Levental I, et al. Motility and stem cell properties induced by the epithelial-mesenchymal transition require destabilization of lipid rafts. Oncotarget. 2016;7:51553-51568 pubmed publisher
  418. Maugeri G, D Amico A, Reitano R, Magro G, Cavallaro S, Salomone S, et al. PACAP and VIP Inhibit the Invasiveness of Glioblastoma Cells Exposed to Hypoxia through the Regulation of HIFs and EGFR Expression. Front Pharmacol. 2016;7:139 pubmed publisher
  419. Fagnocchi L, Cherubini A, Hatsuda H, Fasciani A, Mazzoleni S, Poli V, et al. A Myc-driven self-reinforcing regulatory network maintains mouse embryonic stem cell identity. Nat Commun. 2016;7:11903 pubmed publisher
  420. Cui Y, Zhao J, Yi L, Jiang Y. microRNA-153 Targets mTORC2 Component Rictor to Inhibit Glioma Cells. PLoS ONE. 2016;11:e0156915 pubmed publisher
  421. Saha A, O Connor R, Thangavelu G, Lovitch S, Dandamudi D, Wilson C, et al. Programmed death ligand-1 expression on donor T cells drives graft-versus-host disease lethality. J Clin Invest. 2016;126:2642-60 pubmed publisher
  422. Li W, Jin D, Hata M, Takai S, Yamanishi K, Shen W, et al. Dysfunction of mitochondria and deformed gap junctions in the heart of IL-18-deficient mice. Am J Physiol Heart Circ Physiol. 2016;311:H313-25 pubmed publisher
  423. Priego N, Arechederra M, Sequera C, Bragado P, Vázquez Carballo A, Gutierrez Uzquiza A, et al. C3G knock-down enhances migration and invasion by increasing Rap1-mediated p38? activation, while it impairs tumor growth through p38?-independent mechanisms. Oncotarget. 2016;7:45060-45078 pubmed publisher
  424. Krag T, Pinós T, Nielsen T, Duran J, García Rocha M, Andreu A, et al. Differential glucose metabolism in mice and humans affected by McArdle disease. Am J Physiol Regul Integr Comp Physiol. 2016;311:R307-14 pubmed publisher
  425. Kobayashi K, Araya J, Minagawa S, Hara H, Saito N, Kadota T, et al. Involvement of PARK2-Mediated Mitophagy in Idiopathic Pulmonary Fibrosis Pathogenesis. J Immunol. 2016;197:504-16 pubmed publisher
  426. Tejada T, Tan L, Torres R, Calvert J, Lambert J, Zaidi M, et al. IGF-1 degradation by mouse mast cell protease 4 promotes cell death and adverse cardiac remodeling days after a myocardial infarction. Proc Natl Acad Sci U S A. 2016;113:6949-54 pubmed publisher
  427. Wang J, Farris A, Xu K, Wang P, Zhang X, Duong D, et al. GPRC5A suppresses protein synthesis at the endoplasmic reticulum to prevent radiation-induced lung tumorigenesis. Nat Commun. 2016;7:11795 pubmed publisher
  428. Jeong A, Han S, Lee S, Su Park J, Lu Y, Yu S, et al. Patient derived mutation W257G of PPP2R1A enhances cancer cell migration through SRC-JNK-c-Jun pathway. Sci Rep. 2016;6:27391 pubmed publisher
  429. Foltz S, Luan J, Call J, Patel A, Peissig K, Fortunato M, et al. Four-week rapamycin treatment improves muscular dystrophy in a fukutin-deficient mouse model of dystroglycanopathy. Skelet Muscle. 2016;6:20 pubmed publisher
  430. Fernandez Monreal M, Sánchez Castillo C, Esteban J. APPL1 gates long-term potentiation through its plekstrin homology domain. J Cell Sci. 2016;129:2793-803 pubmed publisher
  431. Tzani I, Ivanov I, Andreev D, Dmitriev R, Dean K, Baranov P, et al. Systematic analysis of the PTEN 5' leader identifies a major AUU initiated proteoform. Open Biol. 2016;6: pubmed publisher
  432. Leonard S, Kinsella G, Benetti E, Findlay J. Regulating the effects of GPR21, a novel target for type 2 diabetes. Sci Rep. 2016;6:27002 pubmed publisher
  433. van Ree J, Nam H, Jeganathan K, Kanakkanthara A, van Deursen J. Pten regulates spindle pole movement through Dlg1-mediated recruitment of Eg5 to centrosomes. Nat Cell Biol. 2016;18:814-21 pubmed publisher
  434. Park J, Kotani T, Konno T, Setiawan J, Kitamura Y, Imada S, et al. Promotion of Intestinal Epithelial Cell Turnover by Commensal Bacteria: Role of Short-Chain Fatty Acids. PLoS ONE. 2016;11:e0156334 pubmed publisher
  435. Kwon H, Choi G, Ryu S, Kwon S, Kim S, Booth C, et al. Stepwise phosphorylation of p65 promotes NF-?B activation and NK cell responses during target cell recognition. Nat Commun. 2016;7:11686 pubmed publisher
  436. Sun F, Zhang Z, Tan E, Lim Z, Li Y, Wang X, et al. Icaritin suppresses development of neuroendocrine differentiation of prostate cancer through inhibition of IL-6/STAT3 and Aurora kinase A pathways in TRAMP mice. Carcinogenesis. 2016;37:701-711 pubmed publisher
  437. Vazirani R, Verma A, Sadacca L, Buckman M, Picatoste B, Beg M, et al. Disruption of Adipose Rab10-Dependent Insulin Signaling Causes Hepatic Insulin Resistance. Diabetes. 2016;65:1577-89 pubmed publisher
  438. Zhang W, Wu M, Kim T, Jariwala R, Garvey W, Luo N, et al. Skeletal Muscle TRIB3 Mediates Glucose Toxicity in Diabetes and High- Fat Diet-Induced Insulin Resistance. Diabetes. 2016;65:2380-91 pubmed publisher
  439. He F, Wei L, Luo W, Liao Z, Li B, Zhou X, et al. Glutaredoxin 3 promotes nasopharyngeal carcinoma growth and metastasis via EGFR/Akt pathway and independent of ROS. Oncotarget. 2016;7:37000-37012 pubmed publisher
  440. Kohler T, Scholz A, Kiachludis D, Hammerschmidt S. Induction of Central Host Signaling Kinases during Pneumococcal Infection of Human THP-1 Cells. Front Cell Infect Microbiol. 2016;6:48 pubmed publisher
  441. Kessler S, Laggai S, Van Wonterg E, Gemperlein K, Muller R, Haybaeck J, et al. Transient Hepatic Overexpression of Insulin-Like Growth Factor 2 Induces Free Cholesterol and Lipid Droplet Formation. Front Physiol. 2016;7:147 pubmed publisher
  442. Gharib M, Tao H, Fungwe T, Hajri T. Cluster Differentiating 36 (CD36) Deficiency Attenuates Obesity-Associated Oxidative Stress in the Heart. PLoS ONE. 2016;11:e0155611 pubmed publisher
  443. Wang J, Hu K, Guo J, Cheng F, Lv J, Jiang W, et al. Suppression of KRas-mutant cancer through the combined inhibition of KRAS with PLK1 and ROCK. Nat Commun. 2016;7:11363 pubmed publisher
  444. Chan E, Shetty M, Sajikumar S, Chen C, Soong T, Wong B. ApoE4 expression accelerates hippocampus-dependent cognitive deficits by enhancing Aβ impairment of insulin signaling in an Alzheimer's disease mouse model. Sci Rep. 2016;6:26119 pubmed publisher
  445. Huang D, Zhao C, Ju R, Kumar A, Tian G, Huang L, et al. VEGF-B inhibits hyperglycemia- and Macugen-induced retinal apoptosis. Sci Rep. 2016;6:26059 pubmed publisher
  446. Wang K, Cao P, Wang H, Tang Z, Wang N, Wang J, et al. Chronic administration of Angelica sinensis polysaccharide effectively improves fatty liver and glucose homeostasis in high-fat diet-fed mice. Sci Rep. 2016;6:26229 pubmed publisher
  447. Song X, Yao Z, Yang J, Zhang Z, Deng Y, Li M, et al. HCV core protein binds to gC1qR to induce A20 expression and inhibit cytokine production through MAPKs and NF-κB signaling pathways. Oncotarget. 2016;7:33796-808 pubmed publisher
  448. Hein A, Post C, Sheinin Y, Lakshmanan I, Natarajan A, Enke C, et al. RAC1 GTPase promotes the survival of breast cancer cells in response to hyper-fractionated radiation treatment. Oncogene. 2016;35:6319-6329 pubmed publisher
  449. Rao E, Zhang Y, Li Q, Hao J, Egilmez N, Suttles J, et al. AMPK-dependent and independent effects of AICAR and compound C on T-cell responses. Oncotarget. 2016;7:33783-95 pubmed publisher
  450. Hsieh M, Yang P, Wong L, Lee J. The AXL receptor tyrosine kinase is associated with adverse prognosis and distant metastasis in esophageal squamous cell carcinoma. Oncotarget. 2016;7:36956-36970 pubmed publisher
  451. Itoh Y, Higuchi M, Oishi K, Kishi Y, Okazaki T, Sakai H, et al. PDK1-Akt pathway regulates radial neuronal migration and microtubules in the developing mouse neocortex. Proc Natl Acad Sci U S A. 2016;113:E2955-64 pubmed publisher
  452. Ting W, Yang J, Kuo C, Xiao Z, Lu X, Yeh Y, et al. Environmental tobacco smoke increases autophagic effects but decreases longevity associated with Sirt-1 protein expression in young C57BL mice hearts. Oncotarget. 2016;7:39017-39025 pubmed publisher
  453. Wang N, Dong B, Quan Y, Chen Q, Chu M, Xu J, et al. Regulation of Prostate Development and Benign Prostatic Hyperplasia by Autocrine Cholinergic Signaling via Maintaining the Epithelial Progenitor Cells in Proliferating Status. Stem Cell Reports. 2016;6:668-678 pubmed publisher
  454. Miyawaki S, Kawamura Y, Oiwa Y, Shimizu A, Hachiya T, Bono H, et al. Tumour resistance in induced pluripotent stem cells derived from naked mole-rats. Nat Commun. 2016;7:11471 pubmed publisher
  455. Cieniewicz A, Cooper P, MCGEHEE J, Lingham R, Kihm A. Novel method demonstrates differential ligand activation and phosphatase-mediated deactivation of insulin receptor tyrosine-specific phosphorylation. Cell Signal. 2016;28:1037-47 pubmed publisher
  456. Segatto I, Massarut S, Boyle R, Baldassarre G, Walker D, Belletti B. Preclinical validation of a novel compound targeting p70S6 kinase in breast cancer. Aging (Albany NY). 2016;8:958-76 pubmed publisher
  457. Huang Y, Lin C, Liao H, Liu C, Chen Y, Chiu W, et al. Cholesterol overload induces apoptosis in SH-SY5Y human neuroblastoma cells through the up regulation of flotillin-2 in the lipid raft and the activation of BDNF/Trkb signaling. Neuroscience. 2016;328:201-9 pubmed publisher
  458. Vorvis C, Hatziapostolou M, Mahurkar Joshi S, Koutsioumpa M, Williams J, Donahue T, et al. Transcriptomic and CRISPR/Cas9 technologies reveal FOXA2 as a tumor suppressor gene in pancreatic cancer. Am J Physiol Gastrointest Liver Physiol. 2016;310:G1124-37 pubmed publisher
  459. Bie Q, Sun C, Gong A, Li C, Su Z, Zheng D, et al. Non-tumor tissue derived interleukin-17B activates IL-17RB/AKT/β-catenin pathway to enhance the stemness of gastric cancer. Sci Rep. 2016;6:25447 pubmed publisher
  460. Xu Z, Mei F, Liu H, Sun C, Zheng Z. C-C Motif Chemokine Receptor 9 Exacerbates Pressure Overload-Induced Cardiac Hypertrophy and Dysfunction. J Am Heart Assoc. 2016;5: pubmed publisher
  461. Plucińska K, Dekeryte R, Koss D, Shearer K, Mody N, Whitfield P, et al. Neuronal human BACE1 knockin induces systemic diabetes in mice. Diabetologia. 2016;59:1513-1523 pubmed publisher
  462. He S, Mansour M, Zimmerman M, Ki D, Layden H, Akahane K, et al. Synergy between loss of NF1 and overexpression of MYCN in neuroblastoma is mediated by the GAP-related domain. elife. 2016;5: pubmed publisher
  463. Choi H, Kim M, Choi Y, Shin Y, Cho S, Ko S. Rhus verniciflua Stokes (RVS) and butein induce apoptosis of paclitaxel-resistant SKOV-3/PAX ovarian cancer cells through inhibition of AKT phosphorylation. BMC Complement Altern Med. 2016;16:122 pubmed publisher
  464. Du R, Liu Z, Hou X, Fu G, An N, Wang L. Trichostatin A potentiates genistein-induced apoptosis and reverses EMT in HEp2 cells. Mol Med Rep. 2016;13:5045-52 pubmed publisher
  465. Qiu X, Wei R, Li Y, Zhu Q, Xiong C, Chen Y, et al. NEDL2 regulates enteric nervous system and kidney development in its Nedd8 ligase activity-dependent manner. Oncotarget. 2016;7:31440-53 pubmed publisher
  466. Noda K, Kitami M, Kitami K, Kaku M, Komatsu Y. Canonical and noncanonical intraflagellar transport regulates craniofacial skeletal development. Proc Natl Acad Sci U S A. 2016;113:E2589-97 pubmed publisher
  467. Stephenson E, Ragauskas A, Jaligama S, Redd J, Parvathareddy J, Peloquin M, et al. Exposure to environmentally persistent free radicals during gestation lowers energy expenditure and impairs skeletal muscle mitochondrial function in adult mice. Am J Physiol Endocrinol Metab. 2016;310:E1003-15 pubmed publisher
  468. Seo J, Singh N, Ottesen E, Sivanesan S, Shishimorova M, Singh R. Oxidative Stress Triggers Body-Wide Skipping of Multiple Exons of the Spinal Muscular Atrophy Gene. PLoS ONE. 2016;11:e0154390 pubmed publisher
  469. Boothe T, Lim G, Cen H, Skovsø S, Piske M, Li S, et al. Inter-domain tagging implicates caveolin-1 in insulin receptor trafficking and Erk signaling bias in pancreatic beta-cells. Mol Metab. 2016;5:366-378 pubmed publisher
  470. Yard B, Adams D, Chie E, Tamayo P, Battaglia J, Gopal P, et al. A genetic basis for the variation in the vulnerability of cancer to DNA damage. Nat Commun. 2016;7:11428 pubmed publisher
  471. Dong F, Ling Q, Ye D, Zhang Z, Shu J, Chen G, et al. TCF7L2 involvement in estradiol- and progesterone-modulated islet and hepatic glucose homeostasis. Sci Rep. 2016;6:24859 pubmed publisher
  472. Chowdhury B, Porter E, Stewart J, Ferreira C, Schipma M, Dykhuizen E. PBRM1 Regulates the Expression of Genes Involved in Metabolism and Cell Adhesion in Renal Clear Cell Carcinoma. PLoS ONE. 2016;11:e0153718 pubmed publisher
  473. Thomas A, Belaidi E, Aron Wisnewsky J, van der Zon G, Levy P, Clement K, et al. Hypoxia-inducible factor prolyl hydroxylase 1 (PHD1) deficiency promotes hepatic steatosis and liver-specific insulin resistance in mice. Sci Rep. 2016;6:24618 pubmed publisher
  474. Monyak R, Emerson D, Schoenfeld B, Zheng X, Chambers D, Rosenfelt C, et al. Insulin signaling misregulation underlies circadian and cognitive deficits in a Drosophila fragile X model. Mol Psychiatry. 2017;22:1140-1148 pubmed publisher
  475. Dokas J, Chadt A, Joost H, Al Hasani H. Tbc1d1 deletion suppresses obesity in leptin-deficient mice. Int J Obes (Lond). 2016;40:1242-9 pubmed publisher
  476. von Mässenhausen A, SANDERS C, Thewes B, Deng M, Queisser A, Vogel W, et al. MERTK as a novel therapeutic target in head and neck cancer. Oncotarget. 2016;7:32678-94 pubmed publisher
  477. Zeng W, Liu Q, Chen Z, Wu X, Zhong Y, Wu J. Silencing of hERG1 Gene Inhibits Proliferation and Invasion, and Induces Apoptosis in Human Osteosarcoma Cells by Targeting the NF-?B Pathway. J Cancer. 2016;7:746-57 pubmed publisher
  478. Kumar A, Abbas W, Colin L, Khan K, Bouchat S, Varin A, et al. Tuning of AKT-pathway by Nef and its blockade by protease inhibitors results in limited recovery in latently HIV infected T-cell line. Sci Rep. 2016;6:24090 pubmed publisher
  479. Jeong J, Noh M, Choi J, Lee H, Kim S. Neuroprotective and antioxidant activities of bamboo salt soy sauce against H2O2-induced oxidative stress in rat cortical neurons. Exp Ther Med. 2016;11:1201-1210 pubmed
  480. Yang E, Ahn S, Lee K, Mahmood U, Kim H. Early Behavioral Abnormalities and Perinatal Alterations of PTEN/AKT Pathway in Valproic Acid Autism Model Mice. PLoS ONE. 2016;11:e0153298 pubmed publisher
  481. Xu K, Wang L, Feng W, Feng Y, Shu H. Phosphatidylinositol-3 kinase-dependent translational regulation of Id1 involves the PPM1G phosphatase. Oncogene. 2016;35:5807-5816 pubmed publisher
  482. Gao Y, Bai X, Zhang D, Han C, Yuan J, Liu W, et al. Mammalian elongation factor 4 regulates mitochondrial translation essential for spermatogenesis. Nat Struct Mol Biol. 2016;23:441-9 pubmed publisher
  483. Huang G, Yang X, Chen K, Xing J, Guo L, Zhu L, et al. Porf-2 Inhibits Neural Stem Cell Proliferation Through Wnt/?-Catenin Pathway by Its GAP Domain. Front Cell Neurosci. 2016;10:85 pubmed publisher
  484. Wen M, Wang J, Chiu Y, Wang M, Lee S, Tai C. N-Cadherin Regulates Cell Migration Through a Rab5-Dependent Temporal Control of Macropinocytosis. Traffic. 2016;17:769-85 pubmed publisher
  485. Palu R, Thummel C. Sir2 Acts through Hepatocyte Nuclear Factor 4 to maintain insulin Signaling and Metabolic Homeostasis in Drosophila. PLoS Genet. 2016;12:e1005978 pubmed publisher
  486. Katlinskaya Y, Katlinski K, Yu Q, Ortiz A, Beiting D, Brice A, et al. Suppression of Type I Interferon Signaling Overcomes Oncogene-Induced Senescence and Mediates Melanoma Development and Progression. Cell Rep. 2016;15:171-180 pubmed publisher
  487. Schlam D, Canton J, Carreño M, Kopinski H, Freeman S, Grinstein S, et al. Gliotoxin Suppresses Macrophage Immune Function by Subverting Phosphatidylinositol 3,4,5-Trisphosphate Homeostasis. MBio. 2016;7:e02242 pubmed publisher
  488. Rorsman C, Tsioumpekou M, Heldin C, Lennartsson J. The Ubiquitin Ligases c-Cbl and Cbl-b Negatively Regulate Platelet-derived Growth Factor (PDGF) BB-induced Chemotaxis by Affecting PDGF Receptor β (PDGFRβ) Internalization and Signaling. J Biol Chem. 2016;291:11608-18 pubmed publisher
  489. Phelps Polirer K, Abt M, Smith D, Yeh E. Co-Targeting of JNK and HUNK in Resistant HER2-Positive Breast Cancer. PLoS ONE. 2016;11:e0153025 pubmed publisher
  490. Rhee M, Lee S, Kim J, Ham D, Park H, Yang H, et al. Preadipocyte factor 1 induces pancreatic ductal cell differentiation into insulin-producing cells. Sci Rep. 2016;6:23960 pubmed publisher
  491. Fearnley G, Smith G, Abdul Zani I, Yuldasheva N, Mughal N, Homer Vanniasinkam S, et al. VEGF-A isoforms program differential VEGFR2 signal transduction, trafficking and proteolysis. Biol Open. 2016;5:571-83 pubmed publisher
  492. Papadakis E, Barker C, Syed H, Reeves T, Schwaiger S, Stuppner H, et al. The Bag-1 inhibitor, Thio-2, reverses an atypical 3D morphology driven by Bag-1L overexpression in a MCF-10A model of ductal carcinoma in situ. Oncogenesis. 2016;5:e215 pubmed publisher
  493. Gandin V, Masvidal L, Cargnello M, Gyenis L, McLaughlan S, Cai Y, et al. mTORC1 and CK2 coordinate ternary and eIF4F complex assembly. Nat Commun. 2016;7:11127 pubmed publisher
  494. Yan B, Zhang Z, Jin D, Cai C, Jia C, Liu W, et al. mTORC1 regulates PTHrP to coordinate chondrocyte growth, proliferation and differentiation. Nat Commun. 2016;7:11151 pubmed publisher
  495. Braley A, Kwak T, Jules J, Harja E, Landgraf R, Hudson B. Regulation of Receptor for Advanced Glycation End Products (RAGE) Ectodomain Shedding and Its Role in Cell Function. J Biol Chem. 2016;291:12057-73 pubmed publisher
  496. Liu D, Bordicchia M, Zhang C, Fang H, Wei W, Li J, et al. Activation of mTORC1 is essential for ?-adrenergic stimulation of adipose browning. J Clin Invest. 2016;126:1704-16 pubmed publisher
  497. Maugeri G, D Amico A, Rasà D, Reitano R, Saccone S, Federico C, et al. Expression profile of Wilms Tumor 1 (WT1) isoforms in undifferentiated and all-trans retinoic acid differentiated neuroblastoma cells. Genes Cancer. 2016;7:47-58 pubmed
  498. Gao Z, Zhang H, Hu F, Yang L, Yang X, Zhu Y, et al. Glycan-deficient PrP stimulates VEGFR2 signaling via glycosaminoglycan. Cell Signal. 2016;28:652-62 pubmed publisher
  499. Mancini M, Lien E, Toker A. Oncogenic AKT1(E17K) mutation induces mammary hyperplasia but prevents HER2-driven tumorigenesis. Oncotarget. 2016;7:17301-13 pubmed publisher
  500. Patzke C, Acuna C, Giam L, Wernig M, Südhof T. Conditional deletion of L1CAM in human neurons impairs both axonal and dendritic arborization and action potential generation. J Exp Med. 2016;213:499-515 pubmed publisher
  501. Meng Y, Zheng L, Yang Y, Wang H, Dong J, Wang C, et al. A monoclonal antibody targeting ErbB2 domain III inhibits ErbB2 signaling and suppresses the growth of ErbB2-overexpressing breast tumors. Oncogenesis. 2016;5:e211 pubmed publisher
  502. Lee I, Maniar K, Lydon J, Kim J. Akt regulates progesterone receptor B-dependent transcription and angiogenesis in endometrial cancer cells. Oncogene. 2016;35:5191-201 pubmed publisher
  503. Agarwal S, Ghosh R, Chen Z, Lakoma A, Gunaratne P, Kim E, et al. Transmembrane adaptor protein PAG1 is a novel tumor suppressor in neuroblastoma. Oncotarget. 2016;7:24018-26 pubmed publisher
  504. Lynch J, McEwen R, Crafter C, McDermott U, Garnett M, Barry S, et al. Identification of differential PI3K pathway target dependencies in T-cell acute lymphoblastic leukemia through a large cancer cell panel screen. Oncotarget. 2016;7:22128-39 pubmed publisher
  505. Lee J, Kim H, Rho S, Lee S. eIF3f reduces tumor growth by directly interrupting clusterin with anti-apoptotic property in cancer cells. Oncotarget. 2016;7:18541-57 pubmed publisher
  506. Hayashi K, Michiue H, Yamada H, Takata K, Nakayama H, Wei F, et al. Fluvoxamine, an anti-depressant, inhibits human glioblastoma invasion by disrupting actin polymerization. Sci Rep. 2016;6:23372 pubmed publisher
  507. Kabe Y, Nakane T, Koike I, Yamamoto T, Sugiura Y, Harada E, et al. Haem-dependent dimerization of PGRMC1/Sigma-2 receptor facilitates cancer proliferation and chemoresistance. Nat Commun. 2016;7:11030 pubmed publisher
  508. Giannogonas P, Apostolou A, Manousopoulou A, Theocharis S, Macari S, Psarras S, et al. Identification of a novel interaction between corticotropin releasing hormone (Crh) and macroautophagy. Sci Rep. 2016;6:23342 pubmed publisher
  509. Morena D, Maestro N, Bersani F, Forni P, Lingua M, Foglizzo V, et al. Hepatocyte Growth Factor-mediated satellite cells niche perturbation promotes development of distinct sarcoma subtypes. elife. 2016;5: pubmed publisher
  510. Lisewski U, Koehncke C, Wilck N, Buschmeyer B, Pieske B, Roepke T. Increased aldosterone-dependent Kv1.5 recycling predisposes to pacing-induced atrial fibrillation in Kcne3-/- mice. FASEB J. 2016;30:2476-89 pubmed publisher
  511. Kurimoto R, Iwasawa S, Ebata T, Ishiwata T, Sekine I, Tada Y, et al. Drug resistance originating from a TGF-β/FGF-2-driven epithelial-to-mesenchymal transition and its reversion in human lung adenocarcinoma cell lines harboring an EGFR mutation. Int J Oncol. 2016;48:1825-36 pubmed publisher
  512. Afsar T, Trembley J, Salomon C, Razak S, Khan M, Ahmed K. Growth inhibition and apoptosis in cancer cells induced by polyphenolic compounds of Acacia hydaspica: Involvement of multiple signal transduction pathways. Sci Rep. 2016;6:23077 pubmed publisher
  513. Apostolidis S, Rodríguez Rodríguez N, Suárez Fueyo A, Dioufa N, Ozcan E, Crispín J, et al. Phosphatase PP2A is requisite for the function of regulatory T cells. Nat Immunol. 2016;17:556-64 pubmed publisher
  514. Winnay J, Solheim M, Dirice E, Sakaguchi M, Noh H, Kang H, et al. PI3-kinase mutation linked to insulin and growth factor resistance in vivo. J Clin Invest. 2016;126:1401-12 pubmed publisher
  515. Kral J, Kuttke M, Schrottmaier W, Birnecker B, Warszawska J, Wernig C, et al. Sustained PI3K Activation exacerbates BLM-induced Lung Fibrosis via activation of pro-inflammatory and pro-fibrotic pathways. Sci Rep. 2016;6:23034 pubmed publisher
  516. Chen S, FORRESTER W, Lahav G. Schedule-dependent interaction between anticancer treatments. Science. 2016;351:1204-8 pubmed publisher
  517. Koussounadis A, Langdon S, Um I, Kay C, Francis K, Harrison D, et al. Dynamic modulation of phosphoprotein expression in ovarian cancer xenograft models. BMC Cancer. 2016;16:205 pubmed publisher
  518. Atiq R, Hertz R, Eldad S, Smeir E, Bar Tana J. Suppression of B-Raf(V600E) cancers by MAPK hyper-activation. Oncotarget. 2016;7:18694-704 pubmed publisher
  519. Hirth S, Bühler A, Bührdel J, Rudeck S, Dahme T, Rottbauer W, et al. Paxillin and Focal Adhesion Kinase (FAK) Regulate Cardiac Contractility in the Zebrafish Heart. PLoS ONE. 2016;11:e0150323 pubmed publisher
  520. Takabatake Y, Oxvig C, Nagi C, Adelson K, Jaffer S, Schmidt H, et al. Lactation opposes pappalysin-1-driven pregnancy-associated breast cancer. EMBO Mol Med. 2016;8:388-406 pubmed publisher
  521. Jang C, Oh S, Wada S, Rowe G, Liu L, Chan M, et al. A branched-chain amino acid metabolite drives vascular fatty acid transport and causes insulin resistance. Nat Med. 2016;22:421-6 pubmed publisher
  522. Yang P, Leu D, Ye K, Srinivasan C, Fike J, Huang T. Cognitive impairments following cranial irradiation can be mitigated by treatment with a tropomyosin receptor kinase B agonist. Exp Neurol. 2016;279:178-186 pubmed publisher
  523. Thakur A, Nigri J, Lac S, Leca J, Bressy C, Berthezene P, et al. TAp73 loss favors Smad-independent TGF-β signaling that drives EMT in pancreatic ductal adenocarcinoma. Cell Death Differ. 2016;23:1358-70 pubmed publisher
  524. Dhar S, Kumar A, Zhang L, Rimando A, Lage J, Lewin J, et al. Dietary pterostilbene is a novel MTA1-targeted chemopreventive and therapeutic agent in prostate cancer. Oncotarget. 2016;7:18469-84 pubmed publisher
  525. Du Z, Li L, Huang X, Jin J, Huang S, Zhang Q, et al. The epigenetic modifier CHD5 functions as a novel tumor suppressor for renal cell carcinoma and is predominantly inactivated by promoter CpG methylation. Oncotarget. 2016;7:21618-30 pubmed publisher
  526. Hu W, Xiao L, Cao C, Hua S, Wu D. UBE2T promotes nasopharyngeal carcinoma cell proliferation, invasion, and metastasis by activating the AKT/GSK3β/β-catenin pathway. Oncotarget. 2016;7:15161-72 pubmed publisher
  527. Ardini E, Menichincheri M, Banfi P, Bosotti R, De Ponti C, Pulci R, et al. Entrectinib, a Pan-TRK, ROS1, and ALK Inhibitor with Activity in Multiple Molecularly Defined Cancer Indications. Mol Cancer Ther. 2016;15:628-39 pubmed publisher
  528. Singh A, Joshi S, Zulcic M, Alcaraz M, GARLICH J, Morales G, et al. PI-3K Inhibitors Preferentially Target CD15+ Cancer Stem Cell Population in SHH Driven Medulloblastoma. PLoS ONE. 2016;11:e0150836 pubmed publisher
  529. Li Y, Wei Z, Dong B, Lian Z, Xu Y. Silencing of phosphoglucose isomerase/autocrine motility factor decreases U87 human glioblastoma cell migration. Int J Mol Med. 2016;37:998-1004 pubmed publisher
  530. Shu M, Hu X, Hung Z, Huang D, Zhang S. Effects of tanshinone IIA on fibrosis in a rat model of cirrhosis through heme oxygenase-1, inflammation, oxidative stress and apoptosis. Mol Med Rep. 2016;13:3036-42 pubmed publisher
  531. Jing H, Sun W, Fan J, Zhang Y, Yang J, Jia J, et al. Shikonin induces apoptosis of HaCaT cells via the mitochondrial, Erk and Akt pathways. Mol Med Rep. 2016;13:3009-16 pubmed publisher
  532. Santio N, Salmela M, Arola H, Eerola S, Heino J, Rainio E, et al. The PIM1 kinase promotes prostate cancer cell migration and adhesion via multiple signalling pathways. Exp Cell Res. 2016;342:113-24 pubmed publisher
  533. Gurnik S, Devraj K, Macas J, Yamaji M, Starke J, Scholz A, et al. Angiopoietin-2-induced blood-brain barrier compromise and increased stroke size are rescued by VE-PTP-dependent restoration of Tie2 signaling. Acta Neuropathol. 2016;131:753-73 pubmed publisher
  534. Lyabin D, Ovchinnikov L. Selective regulation of YB-1 mRNA translation by the mTOR signaling pathway is not mediated by 4E-binding protein. Sci Rep. 2016;6:22502 pubmed publisher
  535. Lee D, Wang Y, Kalaitzidis D, Ramachandran J, Eda H, Sykes D, et al. Endogenous transmembrane protein UT2 inhibits pSTAT3 and suppresses hematological malignancy. J Clin Invest. 2016;126:1300-10 pubmed publisher
  536. Wong H, Jin G, Cao R, Zhang S, Cao Y, Zhou Z. MT1-MMP sheds LYVE-1 on lymphatic endothelial cells and suppresses VEGF-C production to inhibit lymphangiogenesis. Nat Commun. 2016;7:10824 pubmed publisher
  537. Gong Q, Hu Z, Zhang F, Cui A, Chen X, Jiang H, et al. Fibroblast growth factor 21 improves hepatic insulin sensitivity by inhibiting mammalian target of rapamycin complex 1 in mice. Hepatology. 2016;64:425-38 pubmed publisher
  538. Guillot F, Kemppainen S, Lavasseur G, Miettinen P, Laroche S, Tanila H, et al. Brain-Specific Basal and Novelty-Induced Alternations in PI3K-Akt and MAPK/ERK Signaling in a Middle-Aged AβPP/PS1 Mouse Model of Alzheimer's Disease. J Alzheimers Dis. 2016;51:1157-73 pubmed publisher
  539. Chang T, Chen C, Wu Y, Liu J, Kuo Y, Lee K, et al. Inflammation Promotes Expression of Stemness-Related Properties in HBV-Related Hepatocellular Carcinoma. PLoS ONE. 2016;11:e0149897 pubmed publisher
  540. Seip K, Fleten K, Barkovskaya A, Nygaard V, Haugen M, Engesæter B, et al. Fibroblast-induced switching to the mesenchymal-like phenotype and PI3K/mTOR signaling protects melanoma cells from BRAF inhibitors. Oncotarget. 2016;7:19997-20015 pubmed publisher
  541. Mason J, Davison Versagli C, Leliaert A, Pape D, McCallister C, Zuo J, et al. Oncogenic Ras differentially regulates metabolism and anoikis in extracellular matrix-detached cells. Cell Death Differ. 2016;23:1271-82 pubmed publisher
  542. Schwarzer M, Makki K, Storelli G, Machuca Gayet I, Srůtková D, Hermanova P, et al. Lactobacillus plantarum strain maintains growth of infant mice during chronic undernutrition. Science. 2016;351:854-7 pubmed publisher
  543. Viana Huete V, Guillen C, García Aguilar A, García G, Fernandez S, Kahn C, et al. Essential Role of IGFIR in the Onset of Male Brown Fat Thermogenic Function: Regulation of Glucose Homeostasis by Differential Organ-Specific Insulin Sensitivity. Endocrinology. 2016;157:1495-511 pubmed publisher
  544. Bai D, Zhang Y, Shen M, Sun Y, Xia Q, Zhang Y, et al. Hyperglycemia and hyperlipidemia blunts the Insulin-Inpp5f negative feedback loop in the diabetic heart. Sci Rep. 2016;6:22068 pubmed publisher
  545. Wu G, Zeng G. METCAM/MUC18 is a novel tumor and metastasis suppressor for the human ovarian cancer SKOV3 cells. BMC Cancer. 2016;16:136 pubmed publisher
  546. Li M, Lu G, Hu J, Shen X, Ju J, Gao Y, et al. EVA1A/TMEM166 Regulates Embryonic Neurogenesis by Autophagy. Stem Cell Reports. 2016;6:396-410 pubmed publisher
  547. Hu H, Wang H, Xiao Y, Jin J, Chang J, Zou Q, et al. Otud7b facilitates T cell activation and inflammatory responses by regulating Zap70 ubiquitination. J Exp Med. 2016;213:399-414 pubmed publisher
  548. Sancho Martinez I, Nivet E, Xia Y, Hishida T, Aguirre A, Ocampo A, et al. Establishment of human iPSC-based models for the study and targeting of glioma initiating cells. Nat Commun. 2016;7:10743 pubmed publisher
  549. Urnukhsaikhan E, Cho H, Mishig Ochir T, Seo Y, Park J. Pulsed electromagnetic fields promote survival and neuronal differentiation of human BM-MSCs. Life Sci. 2016;151:130-138 pubmed publisher
  550. Tobita T, Guzman Lepe J, Takeishi K, Nakao T, Wang Y, Meng F, et al. SIRT1 Disruption in Human Fetal Hepatocytes Leads to Increased Accumulation of Glucose and Lipids. PLoS ONE. 2016;11:e0149344 pubmed publisher
  551. Liao B, McManus S, Hughes W, Schmitz Peiffer C. Flavin-Containing Monooxygenase 3 Reduces Endoplasmic Reticulum Stress in Lipid-Treated Hepatocytes. Mol Endocrinol. 2016;30:417-28 pubmed publisher
  552. Wang P, Zhang X, Luo P, Jiang X, Zhang P, Guo J, et al. Hepatocyte TRAF3 promotes liver steatosis and systemic insulin resistance through targeting TAK1-dependent signalling. Nat Commun. 2016;7:10592 pubmed publisher
  553. Molteni R, Rossetti A, Savino E, Racagni G, Calabrese F. Chronic Mild Stress Modulates Activity-Dependent Transcription of BDNF in Rat Hippocampal Slices. Neural Plast. 2016;2016:2592319 pubmed publisher
  554. Senol Cosar O, Flach R, DiStefano M, Chawla A, Nicoloro S, Straubhaar J, et al. Tenomodulin promotes human adipocyte differentiation and beneficial visceral adipose tissue expansion. Nat Commun. 2016;7:10686 pubmed publisher
  555. Cui J, Xia T, Xie D, Gao Y, Jia Z, Wei D, et al. HGF/Met and FOXM1 form a positive feedback loop and render pancreatic cancer cells resistance to Met inhibition and aggressive phenotypes. Oncogene. 2016;35:4708-18 pubmed publisher
  556. Hung M, Chen Y, Chu P, Shih C, Yu H, Tai W, et al. Upregulation of the oncoprotein SET determines poor clinical outcomes in hepatocellular carcinoma and shows therapeutic potential. Oncogene. 2016;35:4891-902 pubmed publisher
  557. Minna E, Romeo P, Dugo M, De Cecco L, Todoerti K, Pilotti S, et al. miR-451a is underexpressed and targets AKT/mTOR pathway in papillary thyroid carcinoma. Oncotarget. 2016;7:12731-47 pubmed publisher
  558. Krause C, Popp O, Thirunarayanan N, Dittmar G, Lipp M, Müller G. MicroRNA-34a promotes genomic instability by a broad suppression of genome maintenance mechanisms downstream of the oncogene KSHV-vGPCR. Oncotarget. 2016;7:10414-32 pubmed publisher
  559. Liu T, Fang Z, Wang G, Shi M, Wang X, Jiang K, et al. Anti-tumor activity of the TRPM8 inhibitor BCTC in prostate cancer DU145 cells. Oncol Lett. 2016;11:182-188 pubmed
  560. Demetriades C, Plescher M, Teleman A. Lysosomal recruitment of TSC2 is a universal response to cellular stress. Nat Commun. 2016;7:10662 pubmed publisher
  561. Lakshmipathi J, Alvarez Perez J, Rosselot C, Casinelli G, Stamateris R, Rausell Palamos F, et al. PKCζ Is Essential for Pancreatic β-Cell Replication During Insulin Resistance by Regulating mTOR and Cyclin-D2. Diabetes. 2016;65:1283-96 pubmed publisher
  562. Chang C, Hale S, Cox C, Blair A, Kronsteiner B, Grabowska R, et al. Junctional Adhesion Molecule-A Is Highly Expressed on Human Hematopoietic Repopulating Cells and Associates with the Key Hematopoietic Chemokine Receptor CXCR4. Stem Cells. 2016;34:1664-78 pubmed publisher
  563. Cott C, Thuenauer R, Landi A, Kühn K, Juillot S, Imberty A, et al. Pseudomonas aeruginosa lectin LecB inhibits tissue repair processes by triggering β-catenin degradation. Biochim Biophys Acta. 2016;1863:1106-18 pubmed publisher
  564. Hennig A, Markwart R, Wolff K, Schubert K, Cui Y, Prior I, et al. Feedback activation of neurofibromin terminates growth factor-induced Ras activation. Cell Commun Signal. 2016;14:5 pubmed publisher
  565. Liu Y, Takahashi Y, Desai N, Zhang J, Serfass J, Shi Y, et al. Bif-1 deficiency impairs lipid homeostasis and causes obesity accompanied by insulin resistance. Sci Rep. 2016;6:20453 pubmed publisher
  566. Ding M, Bruick R, Yu Y. Secreted IGFBP5 mediates mTORC1-dependent feedback inhibition of IGF-1 signalling. Nat Cell Biol. 2016;18:319-27 pubmed publisher
  567. White Y, Bagchi A, Van Ziffle J, Inguva A, Bollag G, Zhang C, et al. KRAS insertion mutations are oncogenic and exhibit distinct functional properties. Nat Commun. 2016;7:10647 pubmed publisher
  568. Wang Q, Li J, Wu W, Shen R, Jiang H, Qian Y, et al. Smad4-dependent suppressor pituitary homeobox 2 promotes PPP2R2A-mediated inhibition of Akt pathway in pancreatic cancer. Oncotarget. 2016;7:11208-22 pubmed publisher
  569. Coke C, Scarlett K, Chetram M, Jones K, Sandifer B, Davis A, et al. Simultaneous Activation of Induced Heterodimerization between CXCR4 Chemokine Receptor and Cannabinoid Receptor 2 (CB2) Reveals a Mechanism for Regulation of Tumor Progression. J Biol Chem. 2016;291:9991-10005 pubmed publisher
  570. Egawa H, Jingushi K, Hirono T, Ueda Y, Kitae K, Nakata W, et al. The miR-130 family promotes cell migration and invasion in bladder cancer through FAK and Akt phosphorylation by regulating PTEN. Sci Rep. 2016;6:20574 pubmed publisher
  571. Nakazawa M, Eisinger Mathason T, Sadri N, Ochocki J, Gade T, Amin R, et al. Epigenetic re-expression of HIF-2α suppresses soft tissue sarcoma growth. Nat Commun. 2016;7:10539 pubmed publisher
  572. Ying W, Tseng A, Chang R, Wang H, Lin Y, Kanameni S, et al. miR-150 regulates obesity-associated insulin resistance by controlling B cell functions. Sci Rep. 2016;6:20176 pubmed publisher
  573. Iyer S, Chou F, Wang R, Chiu H, Raju V, Little M, et al. Crim1 has cell-autonomous and paracrine roles during embryonic heart development. Sci Rep. 2016;6:19832 pubmed publisher
  574. Theodosiou M, Widmaier M, Böttcher R, Rognoni E, Veelders M, Bharadwaj M, et al. Kindlin-2 cooperates with talin to activate integrins and induces cell spreading by directly binding paxillin. elife. 2016;5:e10130 pubmed publisher
  575. Button R, Vincent J, Strang C, Luo S. Dual PI-3 kinase/mTOR inhibition impairs autophagy flux and induces cell death independent of apoptosis and necroptosis. Oncotarget. 2016;7:5157-75 pubmed publisher
  576. Grego Bessa J, Bloomekatz J, Castel P, Omelchenko T, Baselga J, Anderson K. The tumor suppressor PTEN and the PDK1 kinase regulate formation of the columnar neural epithelium. elife. 2016;5:e12034 pubmed publisher
  577. Goulielmaki M, Koustas E, Moysidou E, Vlassi M, Sasazuki T, Shirasawa S, et al. BRAF associated autophagy exploitation: BRAF and autophagy inhibitors synergise to efficiently overcome resistance of BRAF mutant colorectal cancer cells. Oncotarget. 2016;7:9188-221 pubmed publisher
  578. Luey B, May F. Insulin-like growth factors are essential to prevent anoikis in oestrogen-responsive breast cancer cells: importance of the type I IGF receptor and PI3-kinase/Akt pathway. Mol Cancer. 2016;15:8 pubmed publisher
  579. Chung S, Moon H, Ju H, Kim D, Cho K, Ribback S, et al. Comparison of liver oncogenic potential among human RAS isoforms. Oncotarget. 2016;7:7354-66 pubmed publisher
  580. Yoshida T, Song L, Bai Y, Kinose F, Li J, Ohaegbulam K, et al. ZEB1 Mediates Acquired Resistance to the Epidermal Growth Factor Receptor-Tyrosine Kinase Inhibitors in Non-Small Cell Lung Cancer. PLoS ONE. 2016;11:e0147344 pubmed publisher
  581. Heynen G, Nevedomskaya E, Palit S, Jagalur Basheer N, Lieftink C, Schlicker A, et al. Mastermind-Like 3 Controls Proliferation and Differentiation in Neuroblastoma. Mol Cancer Res. 2016;14:411-22 pubmed publisher
  582. Chen X, Yang Q, Zheng T, Bian J, Sun X, Shi Y, et al. Neurotrophic Effect of Adipose Tissue-Derived Stem Cells on Erectile Function Recovery by Pigment Epithelium-Derived Factor Secretion in a Rat Model of Cavernous Nerve Injury. Stem Cells Int. 2016;2016:5161248 pubmed publisher
  583. Watari K, Shibata T, Nabeshima H, Shinoda A, Fukunaga Y, Kawahara A, et al. Impaired differentiation of macrophage lineage cells attenuates bone remodeling and inflammatory angiogenesis in Ndrg1 deficient mice. Sci Rep. 2016;6:19470 pubmed publisher
  584. Cherepkova M, Sineva G, Pospelov V. Leukemia inhibitory factor (LIF) withdrawal activates mTOR signaling pathway in mouse embryonic stem cells through the MEK/ERK/TSC2 pathway. Cell Death Dis. 2016;7:e2050 pubmed publisher
  585. Albert V, Svensson K, Shimobayashi M, Colombi M, Munoz S, Jimenez V, et al. mTORC2 sustains thermogenesis via Akt-induced glucose uptake and glycolysis in brown adipose tissue. EMBO Mol Med. 2016;8:232-46 pubmed publisher
  586. Cipriani G, Gibbons S, Verhulst P, Choi K, Eisenman S, Hein S, et al. Diabetic Csf1op/op mice lacking macrophages are protected against the development of delayed gastric emptying. Cell Mol Gastroenterol Hepatol. 2016;2:40-47 pubmed
  587. Pivonello C, Negri M, De Martino M, Napolitano M, De Angelis C, Provvisiero D, et al. The dual targeting of insulin and insulin-like growth factor 1 receptor enhances the mTOR inhibitor-mediated antitumor efficacy in hepatocellular carcinoma. Oncotarget. 2016;7:9718-31 pubmed publisher
  588. Wandinger S, Lahortiga I, Jacobs K, Klammer M, Jordan N, Elschenbroich S, et al. Quantitative Phosphoproteomics Analysis of ERBB3/ERBB4 Signaling. PLoS ONE. 2016;11:e0146100 pubmed publisher
  589. Amato K, Wang S, Tan L, Hastings A, Song W, Lovly C, et al. EPHA2 Blockade Overcomes Acquired Resistance to EGFR Kinase Inhibitors in Lung Cancer. Cancer Res. 2016;76:305-18 pubmed publisher
  590. Kim K, Qiang L, Hayden M, Sparling D, Purcell N, Pajvani U. mTORC1-independent Raptor prevents hepatic steatosis by stabilizing PHLPP2. Nat Commun. 2016;7:10255 pubmed publisher
  591. Carroll B, Maetzel D, Maddocks O, Otten G, Ratcliff M, Smith G, et al. Control of TSC2-Rheb signaling axis by arginine regulates mTORC1 activity. elife. 2016;5: pubmed publisher
  592. Wang X, Tang Z, Yu D, Cui S, Jiang Y, Zhang Q, et al. Epithelial but not stromal expression of collagen alpha-1(III) is a diagnostic and prognostic indicator of colorectal carcinoma. Oncotarget. 2016;7:8823-38 pubmed publisher
  593. Ho N, Morrison J, Silva A, Coomber B. The effect of 3-bromopyruvate on human colorectal cancer cells is dependent on glucose concentration but not hexokinase II expression. Biosci Rep. 2016;36:e00299 pubmed publisher
  594. Jeong J, VanHouten J, Dann P, Kim W, Sullivan C, Yu H, et al. PMCA2 regulates HER2 protein kinase localization and signaling and promotes HER2-mediated breast cancer. Proc Natl Acad Sci U S A. 2016;113:E282-90 pubmed publisher
  595. Lv H, Zhang Z, Wu X, Wang Y, Li C, Gong W, et al. Preclinical Evaluation of Liposomal C8 Ceramide as a Potent anti-Hepatocellular Carcinoma Agent. PLoS ONE. 2016;11:e0145195 pubmed publisher
  596. Yamaguchi T, Lu C, Ida L, Yanagisawa K, Usukura J, Cheng J, et al. ROR1 sustains caveolae and survival signalling as a scaffold of cavin-1 and caveolin-1. Nat Commun. 2016;7:10060 pubmed publisher
  597. Creedon H, Balderstone L, Muir M, Balla J, Gómez Cuadrado L, Tracey N, et al. Use of a genetically engineered mouse model as a preclinical tool for HER2 breast cancer. Dis Model Mech. 2016;9:131-40 pubmed publisher
  598. Maria Z, Campolo A, Lacombe V. Diabetes Alters the Expression and Translocation of the Insulin-Sensitive Glucose Transporters 4 and 8 in the Atria. PLoS ONE. 2015;10:e0146033 pubmed publisher
  599. Zhang H, Xiong Z, Wang J, Zhang S, Lei L, Yang L, et al. Glucagon-like peptide-1 protects cardiomyocytes from advanced oxidation protein product-induced apoptosis via the PI3K/Akt/Bad signaling pathway. Mol Med Rep. 2016;13:1593-601 pubmed publisher
  600. Wang C, Che L, Hu J, Zhang S, Jiang L, Latte G, et al. Activated mutant forms of PIK3CA cooperate with RasV12 or c-Met to induce liver tumour formation in mice via AKT2/mTORC1 cascade. Liver Int. 2016;36:1176-86 pubmed publisher
  601. Hamada D, Maynard R, Schott E, Drinkwater C, Ketz J, Kates S, et al. Suppressive Effects of Insulin on Tumor Necrosis Factor-Dependent Early Osteoarthritic Changes Associated With Obesity and Type 2 Diabetes Mellitus. Arthritis Rheumatol. 2016;68:1392-402 pubmed publisher
  602. Benedykcinska A, Ferreira A, Lau J, Broni J, Richard Loendt A, Henriquez N, et al. Generation of brain tumours in mice by Cre-mediated recombination of neural progenitors in situ with the tamoxifen metabolite endoxifen. Dis Model Mech. 2016;9:211-20 pubmed publisher
  603. Ishibashi T, Yaguchi A, Terada K, Ueno Yokohata H, Tomita O, Iijima K, et al. Ph-like ALL-related novel fusion kinase ATF7IP-PDGFRB exhibits high sensitivity to tyrosine kinase inhibitors in murine cells. Exp Hematol. 2016;44:177-88.e5 pubmed publisher
  604. Schmieg N, Rocchi C, Romeo S, Maggio R, Millan M, Mannoury La Cour C. Dysbindin-1 modifies signaling and cellular localization of recombinant, human D₃ and D₂ receptors. J Neurochem. 2016;136:1037-51 pubmed publisher
  605. Lin H, Masaki H, Yamaguchi T, Wada T, Yachie A, Nishimura K, et al. An assessment of the effects of ectopic gp91phox expression in XCGD iPSC-derived neutrophils. Mol Ther Methods Clin Dev. 2015;2:15046 pubmed publisher
  606. Zhang Y, Fan J, Ho J, Hu T, Kneeland S, Fan X, et al. Crim1 regulates integrin signaling in murine lens development. Development. 2016;143:356-66 pubmed publisher
  607. Yan L, Liu Y, Xiang J, Wu Q, Xu L, Luo X, et al. PIK3R1 targeting by miR-21 suppresses tumor cell migration and invasion by reducing PI3K/AKT signaling and reversing EMT, and predicts clinical outcome of breast cancer. Int J Oncol. 2016;48:471-84 pubmed publisher
  608. Drilon A, Somwar R, Wagner J, Vellore N, Eide C, Zabriskie M, et al. A Novel Crizotinib-Resistant Solvent-Front Mutation Responsive to Cabozantinib Therapy in a Patient with ROS1-Rearranged Lung Cancer. Clin Cancer Res. 2016;22:2351-8 pubmed publisher
  609. Hu Y, Guo R, Wei J, Zhou Y, Ji W, Liu J, et al. Effects of PI3K inhibitor NVP-BKM120 on overcoming drug resistance and eliminating cancer stem cells in human breast cancer cells. Cell Death Dis. 2015;6:e2020 pubmed publisher
  610. Giampietro C, Disanza A, Bravi L, Barrios Rodiles M, Corada M, Frittoli E, et al. The actin-binding protein EPS8 binds VE-cadherin and modulates YAP localization and signaling. J Cell Biol. 2015;211:1177-92 pubmed publisher
  611. Vural A, Al Khodor S, Cheung G, Shi C, Srinivasan L, McQuiston T, et al. Activator of G-Protein Signaling 3-Induced Lysosomal Biogenesis Limits Macrophage Intracellular Bacterial Infection. J Immunol. 2016;196:846-56 pubmed publisher
  612. Franco Villanueva A, Wandosell F, Antón I. Neuritic complexity of hippocampal neurons depends on WIP-mediated mTORC1 and Abl family kinases activities. Brain Behav. 2015;5:e00359 pubmed publisher
  613. Patel A, Yamashita N, Ascano M, Bodmer D, Boehm E, Bodkin Clarke C, et al. RCAN1 links impaired neurotrophin trafficking to aberrant development of the sympathetic nervous system in Down syndrome. Nat Commun. 2015;6:10119 pubmed publisher
  614. Lagarrigue S, Lopez Mejia I, Denechaud P, Escoté X, Castillo Armengol J, Jimenez V, et al. CDK4 is an essential insulin effector in adipocytes. J Clin Invest. 2016;126:335-48 pubmed publisher
  615. Audette D, Anand D, So T, Rubenstein T, Lachke S, Lovicu F, et al. Prox1 and fibroblast growth factor receptors form a novel regulatory loop controlling lens fiber differentiation and gene expression. Development. 2016;143:318-28 pubmed publisher
  616. Kiermaier E, Moussion C, Veldkamp C, Gerardy Schahn R, de Vries I, Williams L, et al. Polysialylation controls dendritic cell trafficking by regulating chemokine recognition. Science. 2016;351:186-90 pubmed publisher
  617. Adam M, Matt S, Christian S, Hess Stumpp H, Haegebarth A, Hofmann T, et al. SIAH ubiquitin ligases regulate breast cancer cell migration and invasion independent of the oxygen status. Cell Cycle. 2015;14:3734-47 pubmed publisher
  618. Yamagishi M, Katano H, Hishima T, Shimoyama T, Ota Y, Nakano K, et al. Coordinated loss of microRNA group causes defenseless signaling in malignant lymphoma. Sci Rep. 2015;5:17868 pubmed publisher
  619. Aimi F, Georgiopoulou S, Kalus I, Lehner F, Hegglin A, Limani P, et al. Endothelial Rictor is crucial for midgestational development and sustained and extensive FGF2-induced neovascularization in the adult. Sci Rep. 2015;5:17705 pubmed publisher
  620. Yamakawa H, Muraoka N, Miyamoto K, Sadahiro T, Isomi M, Haginiwa S, et al. Fibroblast Growth Factors and Vascular Endothelial Growth Factor Promote Cardiac Reprogramming under Defined Conditions. Stem Cell Reports. 2015;5:1128-1142 pubmed publisher
  621. Bo Q, Sun X, Liu J, Sui X, Li G. Antitumor action of the peroxisome proliferator-activated receptor-γ agonist rosiglitazone in hepatocellular carcinoma. Oncol Lett. 2015;10:1979-1984 pubmed
  622. Oudart J, Doué M, Vautrin A, Brassart B, Sellier C, Dupont Deshorgue A, et al. The anti-tumor NC1 domain of collagen XIX inhibits the FAK/ PI3K/Akt/mTOR signaling pathway through αvβ3 integrin interaction. Oncotarget. 2016;7:1516-28 pubmed publisher
  623. Messaoudi S, He Y, Gutsol A, Wight A, Hébert R, Vilmundarson R, et al. Endothelial Gata5 transcription factor regulates blood pressure. Nat Commun. 2015;6:8835 pubmed publisher
  624. Debruyne D, Bhatnagar N, Sharma B, Luther W, Moore N, Cheung N, et al. ALK inhibitor resistance in ALK(F1174L)-driven neuroblastoma is associated with AXL activation and induction of EMT. Oncogene. 2016;35:3681-91 pubmed publisher
  625. O Hayre M, Inoue A, Kufareva I, Wang Z, Mikelis C, Drummond R, et al. Inactivating mutations in GNA13 and RHOA in Burkitt's lymphoma and diffuse large B-cell lymphoma: a tumor suppressor function for the Gα13/RhoA axis in B cells. Oncogene. 2016;35:3771-80 pubmed publisher
  626. Ni Y, Nagashimada M, Zhuge F, Zhan L, Nagata N, Tsutsui A, et al. Astaxanthin prevents and reverses diet-induced insulin resistance and steatohepatitis in mice: A comparison with vitamin E. Sci Rep. 2015;5:17192 pubmed publisher
  627. Green A, Maciel T, Hospital M, Yin C, Mazed F, Townsend E, et al. Pim kinases modulate resistance to FLT3 tyrosine kinase inhibitors in FLT3-ITD acute myeloid leukemia. Sci Adv. 2015;1:e1500221 pubmed publisher
  628. Yasuda K, Takahashi M, Mori N. Mdm20 Modulates Actin Remodeling through the mTORC2 Pathway via Its Effect on Rictor Expression. PLoS ONE. 2015;10:e0142943 pubmed publisher
  629. Ye Z, Al Aidaroos A, Park J, Yuen H, Zhang S, Gupta A, et al. PRL-3 activates mTORC1 in Cancer Progression. Sci Rep. 2015;5:17046 pubmed publisher
  630. Chen J, Chen Y, Yen C, Chen W, Huang W. HBx sensitizes hepatocellular carcinoma cells to lapatinib by up-regulating ErbB3. Oncotarget. 2016;7:473-89 pubmed publisher
  631. McIlroy G, Tammireddy S, Maskrey B, Grant L, Doherty M, Watson D, et al. Fenretinide mediated retinoic acid receptor signalling and inhibition of ceramide biosynthesis regulates adipogenesis, lipid accumulation, mitochondrial function and nutrient stress signalling in adipocytes and adipose tissue. Biochem Pharmacol. 2016;100:86-97 pubmed publisher
  632. E L, Swerdlow R. Lactate's effect on human neuroblastoma cell bioenergetic fluxes. Biochem Pharmacol. 2016;99:88-100 pubmed publisher
  633. Diersch S, Wirth M, Schneeweis C, Jörs S, Geisler F, Siveke J, et al. Kras(G12D) induces EGFR-MYC cross signaling in murine primary pancreatic ductal epithelial cells. Oncogene. 2016;35:3880-6 pubmed publisher
  634. Murata Y, Uehara Y, Hosoi Y. Activation of mTORC1 under nutrient starvation conditions increases cellular radiosensitivity in human liver cancer cell lines, HepG2 and HuH6. Biochem Biophys Res Commun. 2015;468:684-90 pubmed publisher
  635. Hunt L, Xu B, Finkelstein D, Fan Y, Carroll P, Cheng P, et al. The glucose-sensing transcription factor MLX promotes myogenesis via myokine signaling. Genes Dev. 2015;29:2475-89 pubmed publisher
  636. Skeldon A, Morizot A, Douglas T, Santoro N, Kursawe R, Kozlitina J, et al. Caspase-12, but Not Caspase-11, Inhibits Obesity and Insulin Resistance. J Immunol. 2016;196:437-47 pubmed publisher
  637. Wang Z, Ma B, Li H, Xiao X, Zhou W, Liu F, et al. Protein 4.1N acts as a potential tumor suppressor linking PP1 to JNK-c-Jun pathway regulation in NSCLC. Oncotarget. 2016;7:509-23 pubmed publisher
  638. Alsafadi S, Tourpin S, Bessoltane N, Salomé Desnoulez S, Vassal G, André F, et al. Nuclear localization of the caspase-3-cleaved form of p73 in anoikis. Oncotarget. 2016;7:12331-43 pubmed publisher
  639. Momcilovic M, McMickle R, Abt E, Seki A, Simko S, Magyar C, et al. Heightening Energetic Stress Selectively Targets LKB1-Deficient Non-Small Cell Lung Cancers. Cancer Res. 2015;75:4910-22 pubmed publisher
  640. Hu Y, Zhang Y, Tian K, Xun C, Wang S, Lv D. Effects of nerve growth factor and basic fibroblast growth factor dual gene modification on rat bone marrow mesenchymal stem cell differentiation into neuron-like cells in vitro. Mol Med Rep. 2016;13:49-58 pubmed publisher
  641. Shukla P, Vogl C, Wallner B, Rigler D, Müller M, Macho Maschler S. High-throughput mRNA and miRNA profiling of epithelial-mesenchymal transition in MDCK cells. BMC Genomics. 2015;16:944 pubmed publisher
  642. Hu X, Garcia C, Fazli L, Gleave M, Vitek M, Jansen M, et al. Inhibition of Pten deficient Castration Resistant Prostate Cancer by Targeting of the SET - PP2A Signaling axis. Sci Rep. 2015;5:15182 pubmed publisher
  643. Miura S, Sato K, Kato Negishi M, Teshima T, Takeuchi S. Fluid shear triggers microvilli formation via mechanosensitive activation of TRPV6. Nat Commun. 2015;6:8871 pubmed publisher
  644. Clemente Vicario F, Alvarez C, ROWELL J, Roy S, London C, Kisseberth W, et al. Human Genetic Relevance and Potent Antitumor Activity of Heat Shock Protein 90 Inhibition in Canine Lung Adenocarcinoma Cell Lines. PLoS ONE. 2015;10:e0142007 pubmed publisher
  645. Quintero Barceinas R, García Regalado A, Aréchaga Ocampo E, Villegas Sepúlveda N, González De la Rosa C. All-Trans Retinoic Acid Induces Proliferation, Survival, and Migration in A549 Lung Cancer Cells by Activating the ERK Signaling Pathway through a Transcription-Independent Mechanism. Biomed Res Int. 2015;2015:404368 pubmed publisher
  646. Lohberger B, Leithner A, Stuendl N, Kaltenegger H, Kullich W, Steinecker Frohnwieser B. Diacerein retards cell growth of chondrosarcoma cells at the G2/M cell cycle checkpoint via cyclin B1/CDK1 and CDK2 downregulation. BMC Cancer. 2015;15:891 pubmed publisher
  647. Zhang Z, Wu N, Lu Y, Davidson D, Colonna M, Veillette A. DNAM-1 controls NK cell activation via an ITT-like motif. J Exp Med. 2015;212:2165-82 pubmed publisher
  648. Ksionda O, Melton A, Bache J, Tenhagen M, Bakker J, Harvey R, et al. RasGRP1 overexpression in T-ALL increases basal nucleotide exchange on Ras rendering the Ras/PI3K/Akt pathway responsive to protumorigenic cytokines. Oncogene. 2016;35:3658-68 pubmed publisher
  649. Askoxylakis V, Ferraro G, Kodack D, Badeaux M, Shankaraiah R, Seano G, et al. Preclinical Efficacy of Ado-trastuzumab Emtansine in the Brain Microenvironment. J Natl Cancer Inst. 2016;108: pubmed publisher
  650. Goto A, Egawa T, Sakon I, Oshima R, Ito K, Serizawa Y, et al. Heat stress acutely activates insulin-independent glucose transport and 5'-AMP-activated protein kinase prior to an increase in HSP72 protein in rat skeletal muscle. Physiol Rep. 2015;3: pubmed publisher
  651. Yen Y, Hsiao J, Jiang S, Chang J, Wang S, Shen Y, et al. Insulin-like growth factor-independent insulin-like growth factor binding protein 3 promotes cell migration and lymph node metastasis of oral squamous cell carcinoma cells by requirement of integrin β1. Oncotarget. 2015;6:41837-55 pubmed publisher
  652. Jackson E, Rendina Ruedy E, Smith B, Lacombe V. Loss of Toll-Like Receptor 4 Function Partially Protects against Peripheral and Cardiac Glucose Metabolic Derangements During a Long-Term High-Fat Diet. PLoS ONE. 2015;10:e0142077 pubmed publisher
  653. Nikonova A, Deneka A, Eckman L, Kopp M, Hensley H, Egleston B, et al. Opposing Effects of Inhibitors of Aurora-A and EGFR in Autosomal-Dominant Polycystic Kidney Disease. Front Oncol. 2015;5:228 pubmed publisher
  654. Hoshino A, Costa Silva B, Shen T, Rodrigues G, Hashimoto A, Tesic Mark M, et al. Tumour exosome integrins determine organotropic metastasis. Nature. 2015;527:329-35 pubmed publisher
  655. Stanojlović M, Guševac I, Grković I, Zlatković J, Mitrović N, Zarić M, et al. Effects of chronic cerebral hypoperfusion and low-dose progesterone treatment on apoptotic processes, expression and subcellular localization of key elements within Akt and Erk signaling pathways in rat hippocampus. Neuroscience. 2015;311:308-21 pubmed publisher
  656. Lin C, Chen Y, Lin C, Chen Y, Lo G, Lee P, et al. Amiodarone as an autophagy promoter reduces liver injury and enhances liver regeneration and survival in mice after partial hepatectomy. Sci Rep. 2015;5:15807 pubmed publisher
  657. Hirano T, Yasuda H, Tani T, Hamamoto J, Oashi A, Ishioka K, et al. In vitro modeling to determine mutation specificity of EGFR tyrosine kinase inhibitors against clinically relevant EGFR mutants in non-small-cell lung cancer. Oncotarget. 2015;6:38789-803 pubmed publisher
  658. Rizvi F, Mathur A, Krishna S, Siddiqi M, Kakkar P. Suppression in PHLPP2 induction by morin promotes Nrf2-regulated cellular defenses against oxidative injury to primary rat hepatocytes. Redox Biol. 2015;6:587-598 pubmed publisher
  659. Wang Y, Zhang Y, Hu W, Xie S, Gong C, Iqbal K, et al. Rapid alteration of protein phosphorylation during postmortem: implication in the study of protein phosphorylation. Sci Rep. 2015;5:15709 pubmed publisher
  660. Kurozumi A, Goto Y, Matsushita R, Fukumoto I, Kato M, Nishikawa R, et al. Tumor-suppressive microRNA-223 inhibits cancer cell migration and invasion by targeting ITGA3/ITGB1 signaling in prostate cancer. Cancer Sci. 2016;107:84-94 pubmed publisher
  661. Webber P, Park C, Qui M, Ramalingam S, Khuri F, Fu H, et al. Combination of heat shock protein 90 and focal adhesion kinase inhibitors synergistically inhibits the growth of non-small cell lung cancer cells. Oncoscience. 2015;2:765-776 pubmed
  662. Li M, Quan C, Toth R, Campbell D, MacKintosh C, Wang H, et al. Fasting and Systemic Insulin Signaling Regulate Phosphorylation of Brain Proteins That Modulate Cell Morphology and Link to Neurological Disorders. J Biol Chem. 2015;290:30030-41 pubmed publisher
  663. Bauer J, Ozden O, Akagi N, Carroll T, Principe D, Staudacher J, et al. Activin and TGFβ use diverging mitogenic signaling in advanced colon cancer. Mol Cancer. 2015;14:182 pubmed publisher
  664. Zomerman W, Plasschaert S, Diks S, Lourens H, Meeuwsen de Boer T, Hoving E, et al. Exogenous HGF Bypasses the Effects of ErbB Inhibition on Tumor Cell Viability in Medulloblastoma Cell Lines. PLoS ONE. 2015;10:e0141381 pubmed publisher
  665. Verbrugge S, Al M, Assaraf Y, Kammerer S, Chandrupatla D, Honeywell R, et al. Multifactorial resistance to aminopeptidase inhibitor prodrug CHR2863 in myeloid leukemia cells: down-regulation of carboxylesterase 1, drug sequestration in lipid droplets and pro-survival activation ERK/Akt/mTOR. Oncotarget. 2016;7:5240-57 pubmed publisher
  666. Lauková J, Kozubík A, Hofmanová J, Nekvindová J, Sova P, Moyer M, et al. Loss of PTEN Facilitates Rosiglitazone-Mediated Enhancement of Platinum(IV) Complex LA-12-Induced Apoptosis in Colon Cancer Cells. PLoS ONE. 2015;10:e0141020 pubmed publisher
  667. Zhang L, Zhang S, Yao J, Lowery F, Zhang Q, Huang W, et al. Microenvironment-induced PTEN loss by exosomal microRNA primes brain metastasis outgrowth. Nature. 2015;527:100-104 pubmed publisher
  668. Pinel A, Rigaudière J, Laillet B, Pouyet C, Malpuech Brugère C, Prip Buus C, et al. N-3PUFA differentially modulate palmitate-induced lipotoxicity through alterations of its metabolism in C2C12 muscle cells. Biochim Biophys Acta. 2016;1861:12-20 pubmed publisher
  669. Chakedis J, French R, Babicky M, Jaquish D, Howard H, Mose E, et al. A novel protein isoform of the RON tyrosine kinase receptor transforms human pancreatic duct epithelial cells. Oncogene. 2016;35:3249-59 pubmed publisher
  670. Manda K, Tripathi P, Hsi A, Ning J, Ruzinova M, Liapis H, et al. NFATc1 promotes prostate tumorigenesis and overcomes PTEN loss-induced senescence. Oncogene. 2016;35:3282-92 pubmed publisher
  671. Lin K, Kao S, Lai C, Chen C, Wu C, Hsu H, et al. Tumor Suppressor Lzap Suppresses Wnt/β-Catenin Signaling to Promote Zebrafish Embryonic Ventral Cell Fates via the Suppression of Inhibitory Phosphorylation of Glycogen Synthase Kinase 3. J Biol Chem. 2015;290:29808-19 pubmed publisher
  672. Lu R, Herrera B, Eshleman H, Fu Y, Bloom A, Li Z, et al. Shigella Effector OspB Activates mTORC1 in a Manner That Depends on IQGAP1 and Promotes Cell Proliferation. PLoS Pathog. 2015;11:e1005200 pubmed publisher
  673. Sabirzhanov B, Stoica B, Zhao Z, Loane D, Wu J, Dorsey S, et al. miR-711 upregulation induces neuronal cell death after traumatic brain injury. Cell Death Differ. 2016;23:654-68 pubmed publisher
  674. Arriola Apelo S, Neuman J, Baar E, Syed F, Cummings N, Brar H, et al. Alternative rapamycin treatment regimens mitigate the impact of rapamycin on glucose homeostasis and the immune system. Aging Cell. 2016;15:28-38 pubmed publisher
  675. Sugiyama S, Yoshino Y, Kuriyama S, Inoue M, Komine K, Otsuka K, et al. A Curcumin Analog, GO-Y078, Effectively Inhibits Angiogenesis through Actin Disorganization. Anticancer Agents Med Chem. 2016;16:633-47 pubmed
  676. Barbáchano A, Fernández Barral A, Pereira F, Segura M, Ordóñez Morán P, Carrillo de Santa Pau E, et al. SPROUTY-2 represses the epithelial phenotype of colon carcinoma cells via upregulation of ZEB1 mediated by ETS1 and miR-200/miR-150. Oncogene. 2016;35:2991-3003 pubmed publisher
  677. Martínez Revollar G, Garay E, Martín Tapia D, Nava P, Huerta M, Lopez Bayghen E, et al. Heterogeneity between triple negative breast cancer cells due to differential activation of Wnt and PI3K/AKT pathways. Exp Cell Res. 2015;339:67-80 pubmed publisher
  678. Kuo H, Hsu H, Chen Y, Chang Y, Liu F, Wu C. Galectin-3 modulates the EGFR signalling-mediated regulation of Sox2 expression via c-Myc in lung cancer. Glycobiology. 2016;26:155-65 pubmed publisher
  679. Martinez N, Agosto L, Qiu J, Mallory M, Gazzara M, Barash Y, et al. Widespread JNK-dependent alternative splicing induces a positive feedback loop through CELF2-mediated regulation of MKK7 during T-cell activation. Genes Dev. 2015;29:2054-66 pubmed publisher
  680. Luehders K, Sasai N, Davaapil H, Kurosawa Yoshida M, Hiura H, Brah T, et al. The small leucine-rich repeat secreted protein Asporin induces eyes in Xenopus embryos through the IGF signalling pathway. Development. 2015;142:3351-61 pubmed publisher
  681. Payne S, Maher M, Tran N, Van De Hey D, Foley T, Yueh A, et al. PIK3CA mutations can initiate pancreatic tumorigenesis and are targetable with PI3K inhibitors. Oncogenesis. 2015;4:e169 pubmed publisher
  682. Reinardy J, Corey D, Golzio C, Mueller S, Katsanis N, Kontos C. Phosphorylation of Threonine 794 on Tie1 by Rac1/PAK1 Reveals a Novel Angiogenesis Regulatory Pathway. PLoS ONE. 2015;10:e0139614 pubmed publisher
  683. Fan S, Snell C, Turley H, Li J, McCormick R, Perera S, et al. PAT4 levels control amino-acid sensitivity of rapamycin-resistant mTORC1 from the Golgi and affect clinical outcome in colorectal cancer. Oncogene. 2016;35:3004-15 pubmed publisher
  684. Liu L, Li C, Lu Y, Zong X, Luo C, Sun J, et al. Baclofen mediates neuroprotection on hippocampal CA1 pyramidal cells through the regulation of autophagy under chronic cerebral hypoperfusion. Sci Rep. 2015;5:14474 pubmed publisher
  685. Arce Cerezo A, García M, Rodríguez Nuevo A, Crosa Bonell M, Enguix N, Peró A, et al. HMGA1 overexpression in adipose tissue impairs adipogenesis and prevents diet-induced obesity and insulin resistance. Sci Rep. 2015;5:14487 pubmed publisher
  686. Shu X, Wu J, Sun H, Chi L, Wang J. PAK4 confers the malignance of cervical cancers and contributes to the cisplatin-resistance in cervical cancer cells via PI3K/AKT pathway. Diagn Pathol. 2015;10:177 pubmed publisher
  687. Cecchetti S, Bortolomai I, Ferri R, Mercurio L, Canevari S, Podo F, et al. Inhibition of Phosphatidylcholine-Specific Phospholipase C Interferes with Proliferation and Survival of Tumor Initiating Cells in Squamous Cell Carcinoma. PLoS ONE. 2015;10:e0136120 pubmed publisher
  688. Xu Y, Morse L, da Silva R, Wang D, Battaglino R. A short report: PAMM, a novel antioxidant protein, induced by oxidative stress. Redox Biol. 2015;6:446-453 pubmed publisher
  689. Kimball S, Ravi S, Gordon B, Dennis M, Jefferson L. Amino Acid-Induced Activation of mTORC1 in Rat Liver Is Attenuated by Short-Term Consumption of a High-Fat Diet. J Nutr. 2015;145:2496-502 pubmed publisher
  690. Shnitsar I, Bashkurov M, Masson G, Ogunjimi A, Mosessian S, Cabeza E, et al. PTEN regulates cilia through Dishevelled. Nat Commun. 2015;6:8388 pubmed publisher
  691. Haim Y, Bluher M, Slutsky N, Goldstein N, Kloting N, Harman Boehm I, et al. Elevated autophagy gene expression in adipose tissue of obese humans: A potential non-cell-cycle-dependent function of E2F1. Autophagy. 2015;11:2074-2088 pubmed publisher
  692. Leyme A, Marivin A, Perez Gutierrez L, Nguyen L, Garcia Marcos M. Integrins activate trimeric G proteins via the nonreceptor protein GIV/Girdin. J Cell Biol. 2015;210:1165-84 pubmed publisher
  693. Herranz D, Ambesi Impiombato A, Sudderth J, Sánchez Martín M, Belver L, Tosello V, et al. Metabolic reprogramming induces resistance to anti-NOTCH1 therapies in T cell acute lymphoblastic leukemia. Nat Med. 2015;21:1182-9 pubmed publisher
  694. Yokdang N, Hatakeyama J, Wald J, Simion C, Tellez J, Chang D, et al. LRIG1 opposes epithelial-to-mesenchymal transition and inhibits invasion of basal-like breast cancer cells. Oncogene. 2016;35:2932-47 pubmed publisher
  695. Poitelon Y, Bogni S, Matafora V, Della Flora Nunes G, Hurley E, Ghidinelli M, et al. Spatial mapping of juxtacrine axo-glial interactions identifies novel molecules in peripheral myelination. Nat Commun. 2015;6:8303 pubmed publisher
  696. Brina D, Miluzio A, Ricciardi S, Clarke K, Davidsen P, Viero G, et al. eIF6 coordinates insulin sensitivity and lipid metabolism by coupling translation to transcription. Nat Commun. 2015;6:8261 pubmed publisher
  697. Liu R, Yang Y, Shen J, Chen H, Zhang Q, Ba R, et al. Fstl1 is involved in the regulation of radial glial scaffold development. Mol Brain. 2015;8:53 pubmed publisher
  698. Davare M, Vellore N, Wagner J, Eide C, Goodman J, Drilon A, et al. Structural insight into selectivity and resistance profiles of ROS1 tyrosine kinase inhibitors. Proc Natl Acad Sci U S A. 2015;112:E5381-90 pubmed publisher
  699. Harmeier A, Obermueller S, Meyer C, Revel F, Buchy D, Chaboz S, et al. Trace amine-associated receptor 1 activation silences GSK3β signaling of TAAR1 and D2R heteromers. Eur Neuropsychopharmacol. 2015;25:2049-61 pubmed publisher
  700. Kitatani K, Usui T, Sriraman S, Toyoshima M, Ishibashi M, Shigeta S, et al. Ceramide limits phosphatidylinositol-3-kinase C2β-controlled cell motility in ovarian cancer: potential of ceramide as a metastasis-suppressor lipid. Oncogene. 2016;35:2801-12 pubmed publisher
  701. Vennin C, Spruyt N, Dahmani F, Julien S, Bertucci F, Finetti P, et al. H19 non coding RNA-derived miR-675 enhances tumorigenesis and metastasis of breast cancer cells by downregulating c-Cbl and Cbl-b. Oncotarget. 2015;6:29209-23 pubmed publisher
  702. Salim H, Zong D, Hååg P, Novak M, Mörk B, Lewensohn R, et al. DKK1 is a potential novel mediator of cisplatin-refractoriness in non-small cell lung cancer cell lines. BMC Cancer. 2015;15:628 pubmed publisher
  703. Yoo M, Kim B, Lee S, Jeong H, Park J, Seo D, et al. Syntaxin 4 regulates the surface localization of a promyogenic receptor Cdo thereby promoting myogenic differentiation. Skelet Muscle. 2015;5:28 pubmed publisher
  704. Plescher M, Teleman A, Demetriades C. TSC2 mediates hyperosmotic stress-induced inactivation of mTORC1. Sci Rep. 2015;5:13828 pubmed publisher
  705. Jeon J, Kim S, Park K, Yun M. The bifunctional autophagic flux by 2-deoxyglucose to control survival or growth of prostate cancer cells. BMC Cancer. 2015;15:623 pubmed publisher
  706. Mizuno S, Hanamura I, Ota A, Karnan S, Narita T, Ri M, et al. Overexpression of salivary-type amylase reduces the sensitivity to bortezomib in multiple myeloma cells. Int J Hematol. 2015;102:569-78 pubmed publisher
  707. Li M, Yang S, Xing B, Ferguson B, Gulchina Y, Li Y, et al. LY395756, an mGluR2 agonist and mGluR3 antagonist, enhances NMDA receptor expression and function in the normal adult rat prefrontal cortex, but fails to improve working memory and reverse MK801-induced working memory impairment. Exp Neurol. 2015;273:190-201 pubmed publisher
  708. Yao K, Wu J, Zhang J, Bo J, Hong Z, Zu H. Protective Effect of DHT on Apoptosis Induced by U18666A via PI3K/Akt Signaling Pathway in C6 Glial Cell Lines. Cell Mol Neurobiol. 2016;36:801-9 pubmed publisher
  709. Sasaki N, Itakura Y, Toyoda M. Ganglioside GM1 Contributes to the State of Insulin Resistance in Senescent Human Arterial Endothelial Cells. J Biol Chem. 2015;290:25475-86 pubmed publisher
  710. Ebert S, Dyle M, Bullard S, Dierdorff J, Murry D, Fox D, et al. Identification and Small Molecule Inhibition of an Activating Transcription Factor 4 (ATF4)-dependent Pathway to Age-related Skeletal Muscle Weakness and Atrophy. J Biol Chem. 2015;290:25497-511 pubmed publisher
  711. Reuther C, Heinzle V, Spampatti M, Vlotides G, de Toni E, Spöttl G, et al. Cabozantinib and Tivantinib, but Not INC280, Induce Antiproliferative and Antimigratory Effects in Human Neuroendocrine Tumor Cells in vitro: Evidence for 'Off-Target' Effects Not Mediated by c-Met Inhibition. Neuroendocrinology. 2016;103:383-401 pubmed publisher
  712. Thijssen R, Ter Burg J, van Bochove G, de Rooij M, Kuil A, Jansen M, et al. The pan phosphoinositide 3-kinase/mammalian target of rapamycin inhibitor SAR245409 (voxtalisib/XL765) blocks survival, adhesion and proliferation of primary chronic lymphocytic leukemia cells. Leukemia. 2016;30:337-45 pubmed publisher
  713. Xia H, Najafov A, Geng J, Galan Acosta L, Han X, Guo Y, et al. Degradation of HK2 by chaperone-mediated autophagy promotes metabolic catastrophe and cell death. J Cell Biol. 2015;210:705-16 pubmed publisher
  714. Chiang K, Chen H, Hsu S, Pang J, Wang S, Hsu J, et al. PTEN insufficiency modulates ER+ breast cancer cell cycle progression and increases cell growth in vitro and in vivo. Drug Des Devel Ther. 2015;9:4631-8 pubmed publisher
  715. Lee Y, Yun M, Kim H, Jeon B, Park B, Lee B, et al. Exogenous administration of DLK1 ameliorates hepatic steatosis and regulates gluconeogenesis via activation of AMPK. Int J Obes (Lond). 2016;40:356-65 pubmed publisher
  716. Gong Y, Qiu W, Ning X, Yang X, Liu L, Wang Z, et al. CCDC34 is up-regulated in bladder cancer and regulates bladder cancer cell proliferation, apoptosis and migration. Oncotarget. 2015;6:25856-67 pubmed publisher
  717. Zarpelon A, Rodrigues F, Lopes A, Souza G, Carvalho T, Pinto L, et al. Spinal cord oligodendrocyte-derived alarmin IL-33 mediates neuropathic pain. FASEB J. 2016;30:54-65 pubmed publisher
  718. Kumarasamy V, Shin Y, White J, Sun D. Selective repression of RET proto-oncogene in medullary thyroid carcinoma by a natural alkaloid berberine. BMC Cancer. 2015;15:599 pubmed publisher
  719. Feng R, Ye J, Zhou C, Qi L, Fu Z, Yan B, et al. Calreticulin down-regulation inhibits the cell growth, invasion and cell cycle progression of human hepatocellular carcinoma cells. Diagn Pathol. 2015;10:149 pubmed publisher
  720. Tuncay H, Brinkmann B, Steinbacher T, Schürmann A, Gerke V, Iden S, et al. JAM-A regulates cortical dynein localization through Cdc42 to control planar spindle orientation during mitosis. Nat Commun. 2015;6:8128 pubmed publisher
  721. Chang C, Lin W, Pai L, Lee H, Wu S, Ding S, et al. Cytoophidium assembly reflects upregulation of IMPDH activity. J Cell Sci. 2015;128:3550-5 pubmed publisher
  722. Zhao C, Su Y, Zhang J, Feng Q, Qu L, Wang L, et al. Fibrinogen-derived fibrinostatin inhibits tumor growth through anti-angiogenesis. Cancer Sci. 2015;106:1596-606 pubmed publisher
  723. Chang C, Zhang M, Rajapakshe K, Coarfa C, Edwards D, Huang S, et al. Mammary Stem Cells and Tumor-Initiating Cells Are More Resistant to Apoptosis and Exhibit Increased DNA Repair Activity in Response to DNA Damage. Stem Cell Reports. 2015;5:378-91 pubmed publisher
  724. Chang L, Zhao D, Liu H, Wang Q, Zhang P, Li C, et al. Activation of sonic hedgehog signaling enhances cell migration and invasion by induction of matrix metalloproteinase-2 and -9 via the phosphoinositide-3 kinase/AKT signaling pathway in glioblastoma. Mol Med Rep. 2015;12:6702-10 pubmed publisher
  725. Xie R, He W, Shen M, Shou X, Wang Y, Bao W, et al. Specific inhibition of mTOR pathway induces anti-proliferative effect and decreases the hormone secretion in cultured pituitary adenoma cells. J Neurooncol. 2015;125:79-89 pubmed publisher
  726. Garwood C, Ratcliffe L, Morgan S, Simpson J, Owens H, Vazquez Villaseñor I, et al. Insulin and IGF1 signalling pathways in human astrocytes in vitro and in vivo; characterisation, subcellular localisation and modulation of the receptors. Mol Brain. 2015;8:51 pubmed publisher
  727. Sabet O, Stockert R, Xouri G, Brüggemann Y, Stanoev A, Bastiaens P. Ubiquitination switches EphA2 vesicular traffic from a continuous safeguard to a finite signalling mode. Nat Commun. 2015;6:8047 pubmed publisher
  728. Mughal A, Grieg Z, Skjellegrind H, Fayzullin A, Lamkhannat M, Joel M, et al. Knockdown of NAT12/NAA30 reduces tumorigenic features of glioblastoma-initiating cells. Mol Cancer. 2015;14:160 pubmed publisher
  729. Fu Y, Cruz Monserrate Z, Helen Lin H, Chung Y, Ji B, Lin S, et al. Ductal activation of oncogenic KRAS alone induces sarcomatoid phenotype. Sci Rep. 2015;5:13347 pubmed publisher
  730. Barbone D, Follo C, Echeverry N, Gerbaudo V, Klabatsa A, Bueno R, et al. Autophagy Correlates with the Therapeutic Responsiveness of Malignant Pleural Mesothelioma in 3D Models. PLoS ONE. 2015;10:e0134825 pubmed publisher
  731. Chiang C, Uzoma I, Lane D, Memišević V, Alem F, Yao K, et al. A reverse-phase protein microarray-based screen identifies host signaling dynamics upon Burkholderia spp. infection. Front Microbiol. 2015;6:683 pubmed publisher
  732. Álvaro Bartolomé M, García Sevilla J. The neuroplastic index p-FADD/FADD and phosphoprotein PEA-15, interacting at GABAA receptor, are upregulated in brain cortex during midazolam-induced hypnosis in mice. Eur Neuropsychopharmacol. 2015;25:2131-44 pubmed publisher
  733. Sivaraj K, Li R, Albarrán Juárez J, Wang S, Tischner D, Grimm M, et al. Endothelial Gαq/11 is required for VEGF-induced vascular permeability and angiogenesis. Cardiovasc Res. 2015;108:171-80 pubmed publisher
  734. Saeed M, Andreo U, Chung H, Espiritu C, Branch A, Silva J, et al. SEC14L2 enables pan-genotype HCV replication in cell culture. Nature. 2015;524:471-5 pubmed publisher
  735. Hu X, Tang Z, Li Y, Liu W, Zhang S, Wang B, et al. Deletion of the tyrosine phosphatase Shp2 in Sertoli cells causes infertility in mice. Sci Rep. 2015;5:12982 pubmed publisher
  736. Morancho B, Martínez Barriocanal Ã, Villanueva J, Arribas J. Role of ADAM17 in the non-cell autonomous effects of oncogene-induced senescence. Breast Cancer Res. 2015;17:106 pubmed publisher
  737. Zeng Z, Jing D, Zhang X, Duan Y, Xue F. Cyclic mechanical stretch promotes energy metabolism in osteoblast-like cells through an mTOR signaling-associated mechanism. Int J Mol Med. 2015;36:947-56 pubmed publisher
  738. Tzenaki N, Aivaliotis M, Papakonstanti E. Focal adhesion kinase phosphorylates the phosphatase and tensin homolog deleted on chromosome 10 under the control of p110δ phosphoinositide-3 kinase. FASEB J. 2015;29:4840-52 pubmed publisher
  739. Simard E, Söllradl T, Maltais J, Boucher J, D Orléans Juste P, Grandbois M. Receptor for Advanced Glycation End-Products Signaling Interferes with the Vascular Smooth Muscle Cell Contractile Phenotype and Function. PLoS ONE. 2015;10:e0128881 pubmed publisher
  740. Morley T, Xia J, Scherer P. Selective enhancement of insulin sensitivity in the mature adipocyte is sufficient for systemic metabolic improvements. Nat Commun. 2015;6:7906 pubmed publisher
  741. Ahn J, Li J, Chen E, Kent D, Park H, Green A. JAK2V617F mediates resistance to DNA damage-induced apoptosis by modulating FOXO3A localization and Bcl-xL deamidation. Oncogene. 2016;35:2235-46 pubmed publisher
  742. Khalil H, Loukili N, Regamey A, Cuesta Marbán A, Santori E, Huber M, et al. The caspase-3-p120-RasGAP module generates a NF-κB repressor in response to cellular stress. J Cell Sci. 2015;128:3502-13 pubmed publisher
  743. Wostradowski T, Gudi V, Pul R, Gingele S, Lindquist J, Stangel M, et al. Effect of interferon-β1b on CXCR4-dependent chemotaxis in T cells from multiple sclerosis patients. Clin Exp Immunol. 2015;182:162-72 pubmed publisher
  744. Pencik J, Schlederer M, Gruber W, Unger C, Walker S, Chalaris A, et al. STAT3 regulated ARF expression suppresses prostate cancer metastasis. Nat Commun. 2015;6:7736 pubmed publisher
  745. Dahlhoff M, Schäfer M, Muzumdar S, Rose C, Schneider M. ERBB3 is required for tumor promotion in a mouse model of skin carcinogenesis. Mol Oncol. 2015;9:1825-33 pubmed publisher
  746. Luo J, Wu N, Jiang B, Wang L, Wang S, Li X, et al. Marine Bromophenol Derivative 3,4-Dibromo-5-(2-bromo-3,4-dihydroxy-6-isopropoxymethyl benzyl)benzene-1,2-diol Protects Hepatocytes from Lipid-Induced Cell Damage and Insulin Resistance via PTP1B Inhibition. Mar Drugs. 2015;13:4452-69 pubmed publisher
  747. Sarma P, Bag I, Ramaiah M, Kamal A, Bhadra U, Pal Bhadra M. Bisindole-PBD regulates breast cancer cell proliferation via SIRT-p53 axis. Cancer Biol Ther. 2015;16:1486-501 pubmed publisher
  748. Cheng C, Lin J, Tang N, Kao S, Hsieh C. Electroacupuncture at different frequencies (5Hz and 25Hz) ameliorates cerebral ischemia-reperfusion injury in rats: possible involvement of p38 MAPK-mediated anti-apoptotic signaling pathways. BMC Complement Altern Med. 2015;15:241 pubmed publisher
  749. Geletu M, Guy S, Greer S, Raptis L. Differential effects of polyoma virus middle tumor antigen mutants upon gap junctional, intercellular communication. Exp Cell Res. 2015;336:223-31 pubmed publisher
  750. Lee M, Jeong M, Lee H, Han H, Ko A, Hewitt S, et al. PI3K/AKT activation induces PTEN ubiquitination and destabilization accelerating tumourigenesis. Nat Commun. 2015;6:7769 pubmed publisher
  751. Zhou J, Joshi B, Duan X, Pant A, Qiu Z, Kuick R, et al. EGFR Overexpressed in Colonic Neoplasia Can be Detected on Wide-Field Endoscopic Imaging. Clin Transl Gastroenterol. 2015;6:e101 pubmed publisher
  752. Jiang S, Zou Z, Nie P, Wen R, Xiao Y, Tang J. Synergistic Effects between mTOR Complex 1/2 and Glycolysis Inhibitors in Non-Small-Cell Lung Carcinoma Cells. PLoS ONE. 2015;10:e0132880 pubmed publisher
  753. Lin C, Pan C, Wang C, Liu S, Hsiao L, Yang C. Tumor necrosis factor-alpha induces VCAM-1-mediated inflammation via c-Src-dependent transactivation of EGF receptors in human cardiac fibroblasts. J Biomed Sci. 2015;22:53 pubmed publisher
  754. Schipany K, Rosner M, Ionce L, Hengstschläger M, Kovacic B. eIF3 controls cell size independently of S6K1-activity. Oncotarget. 2015;6:24361-75 pubmed
  755. García Pérez D, Laorden M, Milanés M. Regulation of Pleiotrophin, Midkine, Receptor Protein Tyrosine Phosphatase β/ζ, and Their Intracellular Signaling Cascades in the Nucleus Accumbens During Opiate Administration. Int J Neuropsychopharmacol. 2015;19: pubmed publisher
  756. Li Y, Shen C, Zhu B, Shi F, Eisen H, Chen J. Persistent Antigen and Prolonged AKT-mTORC1 Activation Underlie Memory CD8 T Cell Impairment in the Absence of CD4 T Cells. J Immunol. 2015;195:1591-8 pubmed publisher
  757. Gorojod R, Alaimo A, Porte Alcon S, Pomilio C, Saravia F, Kotler M. The autophagic- lysosomal pathway determines the fate of glial cells under manganese- induced oxidative stress conditions. Free Radic Biol Med. 2015;87:237-51 pubmed publisher
  758. Su X, Yu Y, Zhong Y, Giannopoulou E, Hu X, Liu H, et al. Interferon-γ regulates cellular metabolism and mRNA translation to potentiate macrophage activation. Nat Immunol. 2015;16:838-849 pubmed publisher
  759. Laberge R, Sun Y, Orjalo A, Patil C, Freund A, Zhou L, et al. MTOR regulates the pro-tumorigenic senescence-associated secretory phenotype by promoting IL1A translation. Nat Cell Biol. 2015;17:1049-61 pubmed publisher
  760. Reis C, Chen P, Srinivasan S, Aguet F, Mettlen M, Schmid S. Crosstalk between Akt/GSK3β signaling and dynamin-1 regulates clathrin-mediated endocytosis. EMBO J. 2015;34:2132-46 pubmed publisher
  761. McGowan S, McCoy D. Fibroblast growth factor signaling in myofibroblasts differs from lipofibroblasts during alveolar septation in mice. Am J Physiol Lung Cell Mol Physiol. 2015;309:L463-74 pubmed publisher
  762. Zhao L, Liu S, Che X, Hou K, Ma Y, Li C, et al. Bufalin inhibits TGF-β-induced epithelial-to-mesenchymal transition and migration in human lung cancer A549 cells by downregulating TGF-β receptors. Int J Mol Med. 2015;36:645-52 pubmed publisher
  763. Andersson L, Scharin Täng M, Lundqvist A, Lindbom M, Mardani I, Fogelstrand P, et al. Rip2 modifies VEGF-induced signalling and vascular permeability in myocardial ischaemia. Cardiovasc Res. 2015;107:478-86 pubmed publisher
  764. Seo G, Ho M, Bui N, Kim Y, Koh D, Lim Y, et al. Novel naphthochalcone derivative accelerate dermal wound healing through induction of epithelial-mesenchymal transition of keratinocyte. J Biomed Sci. 2015;22:47 pubmed publisher
  765. Ding B, Gomi K, Rafii S, Crystal R, Walters M. Endothelial MMP14 is required for endothelial-dependent growth support of human airway basal cells. J Cell Sci. 2015;128:2983-8 pubmed publisher
  766. Zidek L, Ackermann T, Hartleben G, Eichwald S, Kortman G, Kiehntopf M, et al. Deficiency in mTORC1-controlled C/EBPβ-mRNA translation improves metabolic health in mice. EMBO Rep. 2015;16:1022-36 pubmed publisher
  767. Westcot S, Hatzold J, Urban M, Richetti S, Skuster K, Harm R, et al. Protein-Trap Insertional Mutagenesis Uncovers New Genes Involved in Zebrafish Skin Development, Including a Neuregulin 2a-Based ErbB Signaling Pathway Required during Median Fin Fold Morphogenesis. PLoS ONE. 2015;10:e0130688 pubmed publisher
  768. Pickard A, McDade S, McFarland M, McCluggage W, Wheeler C, McCance D. HPV16 Down-Regulates the Insulin-Like Growth Factor Binding Protein 2 to Promote Epithelial Invasion in Organotypic Cultures. PLoS Pathog. 2015;11:e1004988 pubmed publisher
  769. Tan X, Xue Y, Ma T, Wang X, Li J, Lan L, et al. Partial eNOS deficiency causes spontaneous thrombotic cerebral infarction, amyloid angiopathy and cognitive impairment. Mol Neurodegener. 2015;10:24 pubmed publisher
  770. Chang C, Lin C, Lu C, Martel J, Ko Y, Ojcius D, et al. Ganoderma lucidum reduces obesity in mice by modulating the composition of the gut microbiota. Nat Commun. 2015;6:7489 pubmed publisher
  771. Braccini L, Ciraolo E, Campa C, Perino A, Longo D, Tibolla G, et al. PI3K-C2γ is a Rab5 effector selectively controlling endosomal Akt2 activation downstream of insulin signalling. Nat Commun. 2015;6:7400 pubmed publisher
  772. Carthy J, Sundqvist A, Heldin A, van Dam H, Kletsas D, Heldin C, et al. Tamoxifen Inhibits TGF-β-Mediated Activation of Myofibroblasts by Blocking Non-Smad Signaling Through ERK1/2. J Cell Physiol. 2015;230:3084-92 pubmed publisher
  773. Heinemann A, Cullinane C, De Paoli Iseppi R, Wilmott J, Gunatilake D, Madore J, et al. Combining BET and HDAC inhibitors synergistically induces apoptosis of melanoma and suppresses AKT and YAP signaling. Oncotarget. 2015;6:21507-21 pubmed
  774. Yang L, Li Y, Bhattacharya A, Zhang Y. Inhibition of ERBB2-overexpressing Tumors by Recombinant Human Prolidase and Its Enzymatically Inactive Mutant. EBioMedicine. 2015;2:396-405 pubmed
  775. Hutchinson K, Johnson D, Johnson A, Sanchez V, Kuba M, Lu P, et al. ERBB activation modulates sensitivity to MEK1/2 inhibition in a subset of driver-negative melanoma. Oncotarget. 2015;6:22348-60 pubmed
  776. Li C, Siragy H. (Pro)renin receptor regulates autophagy and apoptosis in podocytes exposed to high glucose. Am J Physiol Endocrinol Metab. 2015;309:E302-10 pubmed publisher
  777. Shen Y, Zeng L, Novosyadlyy R, Forest A, Zhu A, Korytko A, et al. A bi-functional antibody-receptor domain fusion protein simultaneously targeting IGF-IR and VEGF for degradation. MAbs. 2015;7:931-45 pubmed publisher
  778. Stoy C, Sundaram A, Rios Garcia M, Wang X, Seibert O, Zota A, et al. Transcriptional co-factor Transducin beta-like (TBL) 1 acts as a checkpoint in pancreatic cancer malignancy. EMBO Mol Med. 2015;7:1048-62 pubmed publisher
  779. Koos B, Cane G, Grannas K, Löf L, Arngården L, Heldin J, et al. Proximity-dependent initiation of hybridization chain reaction. Nat Commun. 2015;6:7294 pubmed publisher
  780. Albers P, Bojsen Møller K, Dirksen C, Serup A, Kristensen D, Frystyk J, et al. Enhanced insulin signaling in human skeletal muscle and adipose tissue following gastric bypass surgery. Am J Physiol Regul Integr Comp Physiol. 2015;309:R510-24 pubmed publisher
  781. Xie C, Wei D, Zhao L, Marchetto S, Mei L, Borg J, et al. Erbin is a novel substrate of the Sag-βTrCP E3 ligase that regulates KrasG12D-induced skin tumorigenesis. J Cell Biol. 2015;209:721-37 pubmed publisher
  782. Kurppa K, Denessiouk K, Johnson M, Elenius K. Activating ERBB4 mutations in non-small cell lung cancer. Oncogene. 2016;35:1283-91 pubmed publisher
  783. Ching J, Amiridis S, Stylli S, Bjorksten A, Kountouri N, Zheng T, et al. The peroxisome proliferator activated receptor gamma agonist pioglitazone increases functional expression of the glutamate transporter excitatory amino acid transporter 2 (EAAT2) in human glioblastoma cells. Oncotarget. 2015;6:21301-14 pubmed
  784. Jäger W, Xue H, Hayashi T, Janssen C, Awrey S, Wyatt A, et al. Patient-derived bladder cancer xenografts in the preclinical development of novel targeted therapies. Oncotarget. 2015;6:21522-32 pubmed
  785. Min H, Yun H, Lee J, Lee H, Cho J, Jang H, et al. Targeting the insulin-like growth factor receptor and Src signaling network for the treatment of non-small cell lung cancer. Mol Cancer. 2015;14:113 pubmed publisher
  786. Subathra M, Korrapati M, Howell L, Arthur J, Shayman J, Schnellmann R, et al. Kidney glycosphingolipids are elevated early in diabetic nephropathy and mediate hypertrophy of mesangial cells. Am J Physiol Renal Physiol. 2015;309:F204-15 pubmed publisher
  787. Tréhoux S, Lahdaoui F, Delpu Y, Renaud F, Leteurtre E, Torrisani J, et al. Micro-RNAs miR-29a and miR-330-5p function as tumor suppressors by targeting the MUC1 mucin in pancreatic cancer cells. Biochim Biophys Acta. 2015;1853:2392-403 pubmed publisher
  788. Zhang F, Cui J, Lv B, Yu B. Nicorandil protects mesenchymal stem cells against hypoxia and serum deprivation-induced apoptosis. Int J Mol Med. 2015;36:415-23 pubmed publisher
  789. DiPilato L, Ahmad F, Harms M, Seale P, Manganiello V, Birnbaum M. The Role of PDE3B Phosphorylation in the Inhibition of Lipolysis by Insulin. Mol Cell Biol. 2015;35:2752-60 pubmed publisher
  790. Liu D, Xiong H, Ellis A, Northrup N, Dobbin K, Shin D, et al. Canine spontaneous head and neck squamous cell carcinomas represent their human counterparts at the molecular level. PLoS Genet. 2015;11:e1005277 pubmed publisher
  791. Sawada T, Arai D, Jing X, Furushima K, Chen Q, Kawakami K, et al. Trans-Activation between EphA and FGFR Regulates Self-Renewal and Differentiation of Mouse Embryonic Neural Stem/Progenitor Cells via Differential Activation of FRS2α. PLoS ONE. 2015;10:e0128826 pubmed publisher
  792. Vinue A, Andrés Blasco I, Herrero Cervera A, Piqueras L, Andres V, Burks D, et al. Ink4/Arf locus restores glucose tolerance and insulin sensitivity by reducing hepatic steatosis and inflammation in mice with impaired IRS2-dependent signalling. Biochim Biophys Acta. 2015;1852:1729-42 pubmed publisher
  793. Nagata T, Yasukawa H, Kyogoku S, Oba T, Takahashi J, Nohara S, et al. Cardiac-Specific SOCS3 Deletion Prevents In Vivo Myocardial Ischemia Reperfusion Injury through Sustained Activation of Cardioprotective Signaling Molecules. PLoS ONE. 2015;10:e0127942 pubmed publisher
  794. Zhu D, Wang Z, Zhao J, Calimeri T, Meng J, Hideshima T, et al. The Cyclophilin A-CD147 complex promotes the proliferation and homing of multiple myeloma cells. Nat Med. 2015;21:572-80 pubmed publisher
  795. Li L, Qi L, Liang Z, Song W, Liu Y, Wang Y, et al. Transforming growth factor-β1 induces EMT by the transactivation of epidermal growth factor signaling through HA/CD44 in lung and breast cancer cells. Int J Mol Med. 2015;36:113-22 pubmed publisher
  796. Petrov D, Pedrós I, Artiach G, Sureda F, Barroso E, Pallas M, et al. High-fat diet-induced deregulation of hippocampal insulin signaling and mitochondrial homeostasis deficiences contribute to Alzheimer disease pathology in rodents. Biochim Biophys Acta. 2015;1852:1687-99 pubmed publisher
  797. Yu J, Ramasamy T, Murphy N, Holt M, Czapiewski R, Wei S, et al. PI3K/mTORC2 regulates TGF-β/Activin signalling by modulating Smad2/3 activity via linker phosphorylation. Nat Commun. 2015;6:7212 pubmed publisher
  798. Cheung C, Bendris N, Paul C, Hamieh A, Anouar Y, Hahne M, et al. Cyclin A2 modulates EMT via β-catenin and phospholipase C pathways. Carcinogenesis. 2015;36:914-24 pubmed publisher
  799. Li P, Sheu M, Ma W, Pan C, Sheu J, Wu C. Anti-Restenotic Roles of Dihydroaustrasulfone Alcohol Involved in Inhibiting PDGF-BB-Stimulated Proliferation and Migration of Vascular Smooth Muscle Cells. Mar Drugs. 2015;13:3046-60 pubmed publisher
  800. Revuelta López E, Cal R, Herraiz Martínez A, De Gonzalo Calvo D, Nasarre L, Roura S, et al. Hypoxia-driven sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (SERCA2) downregulation depends on low-density lipoprotein receptor-related protein 1 (LRP1)-signalling in cardiomyocytes. J Mol Cell Cardiol. 2015;85:25-36 pubmed publisher
  801. Choi H, Zhang H, Park H, Choi K, Lee H, Agrawal V, et al. Yes-associated protein regulates endothelial cell contact-mediated expression of angiopoietin-2. Nat Commun. 2015;6:6943 pubmed publisher
  802. Heinen A, Beyer F, Tzekova N, Hartung H, Küry P. Fingolimod induces the transition to a nerve regeneration promoting Schwann cell phenotype. Exp Neurol. 2015;271:25-35 pubmed publisher
  803. Cheng H, Liang Y, Kuo Y, Chuu C, Lin C, Lee M, et al. Identification of thioridazine, an antipsychotic drug, as an antiglioblastoma and anticancer stem cell agent using public gene expression data. Cell Death Dis. 2015;6:e1753 pubmed publisher
  804. Rios Doria J, Sabol D, Chesebrough J, Stewart D, Xu L, Tammali R, et al. A Monoclonal Antibody to ADAM17 Inhibits Tumor Growth by Inhibiting EGFR and Non-EGFR-Mediated Pathways. Mol Cancer Ther. 2015;14:1637-49 pubmed publisher
  805. Sadowski S, Boufraqech M, Zhang L, Mehta A, Kapur P, Zhang Y, et al. Torin2 targets dysregulated pathways in anaplastic thyroid cancer and inhibits tumor growth and metastasis. Oncotarget. 2015;6:18038-49 pubmed
  806. Waters A, Stewart J, Atigadda V, Mroczek Musulman E, Muccio D, Grubbs C, et al. Preclinical Evaluation of a Novel RXR Agonist for the Treatment of Neuroblastoma. Mol Cancer Ther. 2015;14:1559-69 pubmed publisher
  807. Liu X, Wang J, Li S, Li L, Huang M, Zhang Y, et al. Histone deacetylase 3 expression correlates with vasculogenic mimicry through the phosphoinositide3-kinase / ERK-MMP-laminin5γ2 signaling pathway. Cancer Sci. 2015;106:857-66 pubmed publisher
  808. Zhang L, Wang H, Ding K, Xu J. FTY720 induces autophagy-related apoptosis and necroptosis in human glioblastoma cells. Toxicol Lett. 2015;236:43-59 pubmed publisher
  809. Buonora J, Mousseau M, Jacobowitz D, Lazarus R, Yarnell A, Olsen C, et al. Autoimmune Profiling Reveals Peroxiredoxin 6 as a Candidate Traumatic Brain Injury Biomarker. J Neurotrauma. 2015;32:1805-14 pubmed publisher
  810. Lee E, Park E, Mun H, Chang E, Ko J, Kim D, et al. Soluble receptor for advanced glycation end products inhibits disease progression in autosomal dominant polycystic kidney disease by down-regulating cell proliferation. FASEB J. 2015;29:3506-14 pubmed publisher
  811. Yeom C, Kim D, Park M, Choi J, Jeong J, Wi A, et al. Insulin-induced CARM1 upregulation facilitates hepatocyte proliferation. Biochem Biophys Res Commun. 2015;461:568-74 pubmed publisher
  812. Dungan C, Li Z, Wright D, Williamson D. Hyperactive mTORC1 signaling is unaffected by metformin treatment in aged skeletal muscle. Muscle Nerve. 2016;53:107-17 pubmed publisher
  813. Park J, Zhao L, Willingham M, Cheng S. Oncogenic mutations of thyroid hormone receptor β. Oncotarget. 2015;6:8115-31 pubmed
  814. Quan C, Xie B, Wang H, Chen S. PKB-Mediated Thr649 Phosphorylation of AS160/TBC1D4 Regulates the R-Wave Amplitude in the Heart. PLoS ONE. 2015;10:e0124491 pubmed publisher
  815. Mendonsa A, Chalfant M, Gorden L, VanSaun M. Modulation of the leptin receptor mediates tumor growth and migration of pancreatic cancer cells. PLoS ONE. 2015;10:e0126686 pubmed publisher
  816. Zhang W, Zhu Y, Yang J, Yang G, Zhou D, Wang J. A Selected Lactobacillus rhamnosus Strain Promotes EGFR-Independent Akt Activation in an Enterotoxigenic Escherichia coli K88-Infected IPEC-J2 Cell Model. PLoS ONE. 2015;10:e0125717 pubmed publisher
  817. Pasqualon T, Pruessmeyer J, Weidenfeld S, Babendreyer A, Groth E, Schumacher J, et al. A transmembrane C-terminal fragment of syndecan-1 is generated by the metalloproteinase ADAM17 and promotes lung epithelial tumor cell migration and lung metastasis formation. Cell Mol Life Sci. 2015;72:3783-801 pubmed publisher
  818. Ledee D, Kajimoto M, O Kelly Priddy C, Olson A, Isern N, Robillard Frayne I, et al. Pyruvate modifies metabolic flux and nutrient sensing during extracorporeal membrane oxygenation in an immature swine model. Am J Physiol Heart Circ Physiol. 2015;309:H137-46 pubmed publisher
  819. Liu H, Du L, Wang R, Wei C, Liu B, Zhu L, et al. High frequency of loss of PTEN expression in human solid salivary adenoid cystic carcinoma and its implication for targeted therapy. Oncotarget. 2015;6:11477-91 pubmed
  820. Jang D, Kwon H, Jeong K, Lee J, Pak Y. Essential role of flotillin-1 palmitoylation in the intracellular localization and signaling function of IGF-1 receptor. J Cell Sci. 2015;128:2179-90 pubmed publisher
  821. Chen H, Huang W, Yang L, Lin C. The PTEN-AKT-mTOR/RICTOR Pathway in Nasal Natural Killer Cell Lymphoma Is Activated by miR-494-3p via PTEN But Inhibited by miR-142-3p via RICTOR. Am J Pathol. 2015;185:1487-99 pubmed publisher
  822. Kim H, Kim I, Dong Y, Lee I, Kim J, Kim J, et al. Melanogenesis-inducing effect of cirsimaritin through increases in microphthalmia-associated transcription factor and tyrosinase expression. Int J Mol Sci. 2015;16:8772-88 pubmed publisher
  823. Bugaj L, Spelke D, Mesuda C, Varedi M, Kane R, Schaffer D. Regulation of endogenous transmembrane receptors through optogenetic Cry2 clustering. Nat Commun. 2015;6:6898 pubmed publisher
  824. Koenig S, Moreau C, Dupont G, Scoumanne A, Erneux C. Regulation of NGF-driven neurite outgrowth by Ins(1,4,5)P3 kinase is specifically associated with the two isoenzymes Itpka and Itpkb in a model of PC12 cells. FEBS J. 2015;282:2553-69 pubmed publisher
  825. Roffé M, Lupinacci F, Soares L, Hajj G, Martins V. Two widely used RSK inhibitors, BI-D1870 and SL0101, alter mTORC1 signaling in a RSK-independent manner. Cell Signal. 2015;27:1630-42 pubmed publisher
  826. Moreira J, Wohlwend M, Alves M, Wisløff U, Bye A. A small molecule activator of AKT does not reduce ischemic injury of the rat heart. J Transl Med. 2015;13:76 pubmed publisher
  827. Bettaieb A, Jiang J, Sasaki Y, Chao T, Kiss Z, Chen X, et al. Hepatocyte Nicotinamide Adenine Dinucleotide Phosphate Reduced Oxidase 4 Regulates Stress Signaling, Fibrosis, and Insulin Sensitivity During Development of Steatohepatitis in Mice. Gastroenterology. 2015;149:468-80.e10 pubmed publisher
  828. Cookman C, Belcher S. Estrogen Receptor-β Up-Regulates IGF1R Expression and Activity to Inhibit Apoptosis and Increase Growth of Medulloblastoma. Endocrinology. 2015;156:2395-408 pubmed publisher
  829. Tancioni I, Miller N, Uryu S, Lawson C, Jean C, Chen X, et al. FAK activity protects nucleostemin in facilitating breast cancer spheroid and tumor growth. Breast Cancer Res. 2015;17:47 pubmed publisher
  830. Chien P, Lin C, Hsiao L, Yang C. c-Src/Pyk2/EGFR/PI3K/Akt/CREB-activated pathway contributes to human cardiomyocyte hypertrophy: Role of COX-2 induction. Mol Cell Endocrinol. 2015;409:59-72 pubmed publisher
  831. Ip L, Poulogiannis G, Viciano F, Sasaki J, Kofuji S, Spanswick V, et al. Loss of INPP4B causes a DNA repair defect through loss of BRCA1, ATM and ATR and can be targeted with PARP inhibitor treatment. Oncotarget. 2015;6:10548-62 pubmed
  832. Navis A, van Lith S, van Duijnhoven S, de Pooter M, Yetkin Arik B, Wesseling P, et al. Identification of a novel MET mutation in high-grade glioma resulting in an auto-active intracellular protein. Acta Neuropathol. 2015;130:131-44 pubmed publisher
  833. Ohashi M, Holthaus A, Calderwood M, Lai C, Krastins B, Sarracino D, et al. The EBNA3 family of Epstein-Barr virus nuclear proteins associates with the USP46/USP12 deubiquitination complexes to regulate lymphoblastoid cell line growth. PLoS Pathog. 2015;11:e1004822 pubmed publisher
  834. Janes K. An analysis of critical factors for quantitative immunoblotting. Sci Signal. 2015;8:rs2 pubmed publisher
  835. Ota A, Kovary K, Wu O, Ahrends R, Shen W, Costa M, et al. Using SRM-MS to quantify nuclear protein abundance differences between adipose tissue depots of insulin-resistant mice. J Lipid Res. 2015;56:1068-78 pubmed publisher
  836. Sadok A, McCarthy A, Caldwell J, Collins I, Garrett M, Yeo M, et al. Rho kinase inhibitors block melanoma cell migration and inhibit metastasis. Cancer Res. 2015;75:2272-84 pubmed publisher
  837. Brohée L, Demine S, Willems J, Arnould T, Colige A, Deroanne C. Lipin-1 regulates cancer cell phenotype and is a potential target to potentiate rapamycin treatment. Oncotarget. 2015;6:11264-80 pubmed
  838. Yamakoshi K, Katano S, Iida M, Kimura H, Okuma A, Ikemoto Uezumi M, et al. Dysregulation of the Bmi-1/p16(Ink⁴a) pathway provokes an aging-associated decline of submandibular gland function. Aging Cell. 2015;14:616-24 pubmed publisher
  839. Zhang W, Hou J, Wang X, Jiang R, Yin Y, Ji J, et al. PTPRO-mediated autophagy prevents hepatosteatosis and tumorigenesis. Oncotarget. 2015;6:9420-33 pubmed
  840. Shi Y, Chen J, Karner C, Long F. Hedgehog signaling activates a positive feedback mechanism involving insulin-like growth factors to induce osteoblast differentiation. Proc Natl Acad Sci U S A. 2015;112:4678-83 pubmed publisher
  841. Zhang Z, Zhang T, Zhou Y, Wei X, Zhu J, Zhang J, et al. Activated phosphatidylinositol 3-kinase/Akt inhibits the transition of endothelial progenitor cells to mesenchymal cells by regulating the forkhead box subgroup O-3a signaling. Cell Physiol Biochem. 2015;35:1643-53 pubmed publisher
  842. Marathe S, Liu S, Brai E, Kaczarowski M, Alberi L. Notch signaling in response to excitotoxicity induces neurodegeneration via erroneous cell cycle reentry. Cell Death Differ. 2015;22:1775-84 pubmed publisher
  843. Ye R, Wang M, Wang Q, Scherer P. Adiponectin-mediated antilipotoxic effects in regenerating pancreatic islets. Endocrinology. 2015;156:2019-28 pubmed publisher
  844. Fallahi Sichani M, Moerke N, Niepel M, Zhang T, Gray N, Sorger P. Systematic analysis of BRAF(V600E) melanomas reveals a role for JNK/c-Jun pathway in adaptive resistance to drug-induced apoptosis. Mol Syst Biol. 2015;11:797 pubmed publisher
  845. Hoekstra E, Kodach L, Das A, Ruela de Sousa R, Ferreira C, Hardwick J, et al. Low molecular weight protein tyrosine phosphatase (LMWPTP) upregulation mediates malignant potential in colorectal cancer. Oncotarget. 2015;6:8300-12 pubmed
  846. Balhara B, Burkart A, Topcu V, Lee Y, Cowan C, Kahn C, et al. Severe insulin resistance alters metabolism in mesenchymal progenitor cells. Endocrinology. 2015;156:2039-48 pubmed publisher
  847. Yazlovitskaya E, Tseng H, Viquez O, Tu T, Mernaugh G, McKee K, et al. Integrin α3β1 regulates kidney collecting duct development via TRAF6-dependent K63-linked polyubiquitination of Akt. Mol Biol Cell. 2015;26:1857-74 pubmed publisher
  848. Chan N, He S, Spee C, Ishikawa K, Hinton D. Attenuation of choroidal neovascularization by histone deacetylase inhibitor. PLoS ONE. 2015;10:e0120587 pubmed publisher
  849. Kann M, Bae E, Lenz M, Li L, Trannguyen B, Schumacher V, et al. WT1 targets Gas1 to maintain nephron progenitor cells by modulating FGF signals. Development. 2015;142:1254-66 pubmed publisher
  850. Venkatesh A, Ma S, Le Y, Hall M, Rüegg M, Punzo C. Activated mTORC1 promotes long-term cone survival in retinitis pigmentosa mice. J Clin Invest. 2015;125:1446-58 pubmed publisher
  851. Graziani G, Artuso S, De Luca A, Muzi A, Rotili D, Scimeca M, et al. A new water soluble MAPK activator exerts antitumor activity in melanoma cells resistant to the BRAF inhibitor vemurafenib. Biochem Pharmacol. 2015;95:16-27 pubmed publisher
  852. Tapia O, Fong L, Huber M, Young S, Gerace L. Nuclear envelope protein Lem2 is required for mouse development and regulates MAP and AKT kinases. PLoS ONE. 2015;10:e0116196 pubmed publisher
  853. Kawada M, Inoue H, Ohba S, Yoshida J, Masuda T, Yamasaki M, et al. Stromal cells positively and negatively modulate the growth of cancer cells: stimulation via the PGE2-TNFα-IL-6 pathway and inhibition via secreted GAPDH-E-cadherin interaction. PLoS ONE. 2015;10:e0119415 pubmed publisher
  854. Brulhart Meynet M, Braunersreuther V, Brinck J, Montecucco F, Prost J, Thomas A, et al. Improving reconstituted HDL composition for efficient post-ischemic reduction of ischemia reperfusion injury. PLoS ONE. 2015;10:e0119664 pubmed publisher
  855. Harris White M, Ferbas K, Johnson M, Eslami P, Poteshkina A, Venkova K, et al. A cell-penetrating ester of the neural metabolite lanthionine ketimine stimulates autophagy through the mTORC1 pathway: Evidence for a mechanism of action with pharmacological implications for neurodegenerative pathologies. Neurobiol Dis. 2015;84:60-8 pubmed publisher
  856. Ma W, Na M, Tang C, Wang H, Lin Z. Overexpression of N-myc downstream-regulated gene 1 inhibits human glioma proliferation and invasion via phosphoinositide 3-kinase/AKT pathways. Mol Med Rep. 2015;12:1050-8 pubmed publisher
  857. Panneerselvam J, Jin J, Shanker M, Lauderdale J, BATES J, Wang Q, et al. IL-24 inhibits lung cancer cell migration and invasion by disrupting the SDF-1/CXCR4 signaling axis. PLoS ONE. 2015;10:e0122439 pubmed publisher
  858. Qiao Y, Shiue C, Zhu J, Zhuang T, Jonsson P, Wright A, et al. AP-1-mediated chromatin looping regulates ZEB2 transcription: new insights into TNFα-induced epithelial-mesenchymal transition in triple-negative breast cancer. Oncotarget. 2015;6:7804-14 pubmed
  859. Gorantla S, Zirlik K, Reiter A, Yu C, Illert A, von Bubnoff N, et al. F604S exchange in FIP1L1-PDGFRA enhances FIP1L1-PDGFRA protein stability via SHP-2 and SRC: a novel mode of kinase inhibitor resistance. Leukemia. 2015;29:1763-70 pubmed publisher
  860. Maione F, Oliaro Bosso S, Meda C, Di Nicolantonio F, Bussolino F, Balliano G, et al. The cholesterol biosynthesis enzyme oxidosqualene cyclase is a new target to impair tumour angiogenesis and metastasis dissemination. Sci Rep. 2015;5:9054 pubmed publisher
  861. Rao E, Zhang Y, Zhu G, Hao J, Persson X, Egilmez N, et al. Deficiency of AMPK in CD8+ T cells suppresses their anti-tumor function by inducing protein phosphatase-mediated cell death. Oncotarget. 2015;6:7944-58 pubmed
  862. Zhang W, Cai J, Chen S, Zheng X, Hu S, Dong W, et al. Paclitaxel resistance in MCF-7/PTX cells is reversed by paeonol through suppression of the SET/phosphatidylinositol 3-kinase/Akt pathway. Mol Med Rep. 2015;12:1506-14 pubmed publisher
  863. Wengrod J, Wang D, Weiss S, Zhong H, Osman I, Gardner L. Phosphorylation of eIF2α triggered by mTORC1 inhibition and PP6C activation is required for autophagy and is aberrant in PP6C-mutated melanoma. Sci Signal. 2015;8:ra27 pubmed publisher
  864. Wilson F, Johannessen C, Piccioni F, Tamayo P, Kim J, Van Allen E, et al. A functional landscape of resistance to ALK inhibition in lung cancer. Cancer Cell. 2015;27:397-408 pubmed publisher
  865. Lin Y, Yang Z, Xu A, Dong P, Huang Y, Liu H, et al. PIK3R1 negatively regulates the epithelial-mesenchymal transition and stem-like phenotype of renal cancer cells through the AKT/GSK3β/CTNNB1 signaling pathway. Sci Rep. 2015;5:8997 pubmed publisher
  866. Geurts L, Everard A, Van Hul M, Essaghir A, Duparc T, Matamoros S, et al. Adipose tissue NAPE-PLD controls fat mass development by altering the browning process and gut microbiota. Nat Commun. 2015;6:6495 pubmed publisher
  867. Münzberg C, Höhn K, Krndija D, Maaß U, Bartsch D, Slater E, et al. IGF-1 drives chromogranin A secretion via activation of Arf1 in human neuroendocrine tumour cells. J Cell Mol Med. 2015;19:948-59 pubmed publisher
  868. Chu D, Zhang Z, Zhou Y, Li Y, Zhu S, Zhang J, et al. NDRG4, a novel candidate tumor suppressor, is a predictor of overall survival of colorectal cancer patients. Oncotarget. 2015;6:7584-96 pubmed
  869. McKee C, Sigala B, Soeda J, Mouralidarane A, Morgan M, Mazzoccoli G, et al. Amphiregulin activates human hepatic stellate cells and is upregulated in non alcoholic steatohepatitis. Sci Rep. 2015;5:8812 pubmed publisher
  870. Wu J, Pipathsouk A, Keizer Gunnink A, Fusetti F, Alkema W, Liu S, et al. Homer3 regulates the establishment of neutrophil polarity. Mol Biol Cell. 2015;26:1629-39 pubmed publisher
  871. Vogel C, Smit M, Maddalo G, Possik P, Sparidans R, van der Burg S, et al. Cooperative induction of apoptosis in NRAS mutant melanoma by inhibition of MEK and ROCK. Pigment Cell Melanoma Res. 2015;28:307-17 pubmed publisher
  872. Yi Y, Kang H, Bae E, Oh S, Seong Y, Bae I. β-TrCP1 degradation is a novel action mechanism of PI3K/mTOR inhibitors in triple-negative breast cancer cells. Exp Mol Med. 2015;47:e143 pubmed publisher
  873. Sanjurjo L, Amézaga N, Aran G, Naranjo Gómez M, Arias L, Armengol C, et al. The human CD5L/AIM-CD36 axis: A novel autophagy inducer in macrophages that modulates inflammatory responses. Autophagy. 2015;11:487-502 pubmed publisher
  874. Stolze B, Reinhart S, Bulllinger L, Fröhling S, Scholl C. Comparative analysis of KRAS codon 12, 13, 18, 61, and 117 mutations using human MCF10A isogenic cell lines. Sci Rep. 2015;5:8535 pubmed publisher
  875. Zhu M, Guo J, Li W, Lu Y, Fu S, Xie X, et al. Hepatitis B virus X protein induces expression of alpha-fetoprotein and activates PI3K/mTOR signaling pathway in liver cells. Oncotarget. 2015;6:12196-208 pubmed
  876. Fumagalli I, Dugue D, Bibault J, Clémenson C, Vozenin M, Mondini M, et al. Cytotoxic effect of lapatinib is restricted to human papillomavirus-positive head and neck squamous cell carcinoma cell lines. Onco Targets Ther. 2015;8:335-45 pubmed publisher
  877. Okita N, Honda Y, Kishimoto N, Liao W, Azumi E, Hashimoto Y, et al. Supplementation of strontium to a chondrogenic medium promotes chondrogenic differentiation of human dedifferentiated fat cells. Tissue Eng Part A. 2015;21:1695-704 pubmed publisher
  878. Momeny M, Saunus J, Marturana F, McCart Reed A, Black D, Sala G, et al. Heregulin-HER3-HER2 signaling promotes matrix metalloproteinase-dependent blood-brain-barrier transendothelial migration of human breast cancer cell lines. Oncotarget. 2015;6:3932-46 pubmed
  879. Jeffery J, Neyt C, Moore W, Paterson S, Bower N, Chenevix Trench G, et al. Cep55 regulates embryonic growth and development by promoting Akt stability in zebrafish. FASEB J. 2015;29:1999-2009 pubmed publisher
  880. Kodigepalli K, Nanjundan M. Induction of PLSCR1 in a STING/IRF3-dependent manner upon vector transfection in ovarian epithelial cells. PLoS ONE. 2015;10:e0117464 pubmed publisher
  881. Dametto P, Lakkaraju A, Bridel C, Villiger L, O CONNOR T, Herrmann U, et al. Neurodegeneration and unfolded-protein response in mice expressing a membrane-tethered flexible tail of PrP. PLoS ONE. 2015;10:e0117412 pubmed publisher
  882. Castorina A, Waschek J, Marzagalli R, Cardile V, Drago F. PACAP interacts with PAC1 receptors to induce tissue plasminogen activator (tPA) expression and activity in schwann cell-like cultures. PLoS ONE. 2015;10:e0117799 pubmed publisher
  883. Papadakis A, Sun C, Knijnenburg T, Xue Y, Grernrum W, Hölzel M, et al. SMARCE1 suppresses EGFR expression and controls responses to MET and ALK inhibitors in lung cancer. Cell Res. 2015;25:445-58 pubmed publisher
  884. Barrichon M, Hadi T, Wendremaire M, Ptasinski C, Seigneuric R, Marcion G, et al. Dose-dependent biphasic leptin-induced proliferation is caused by non-specific IL-6/NF-κB pathway activation in human myometrial cells. Br J Pharmacol. 2015;172:2974-90 pubmed publisher
  885. González N, Martín Duce A, Martínez Arrieta F, Moreno Villegas Z, Portal Núñez S, Sanz R, et al. Effect of bombesin receptor subtype-3 and its synthetic agonist on signaling, glucose transport and metabolism in myocytes from patients with obesity and type 2 diabetes. Int J Mol Med. 2015;35:925-31 pubmed publisher
  886. Schreiber K, Ortiz D, Academia E, Anies A, Liao C, Kennedy B. Rapamycin-mediated mTORC2 inhibition is determined by the relative expression of FK506-binding proteins. Aging Cell. 2015;14:265-73 pubmed publisher
  887. Ju B, Chen W, Orr B, Spitsbergen J, Jia S, Eden C, et al. Oncogenic KRAS promotes malignant brain tumors in zebrafish. Mol Cancer. 2015;14:18 pubmed publisher
  888. Kozlova N, Samoylenko A, Drobot L, Kietzmann T. Urokinase is a negative modulator of Egf-dependent proliferation and motility in the two breast cancer cell lines MCF-7 and MDA-MB-231. Mol Carcinog. 2016;55:170-81 pubmed publisher
  889. Li S, Bhave D, Chow J, Riera T, Schlee S, Rauch S, et al. Quantitative analysis of receptor tyrosine kinase-effector coupling at functionally relevant stimulus levels. J Biol Chem. 2015;290:10018-36 pubmed publisher
  890. Shaw A, Pickup M, Chytil A, Aakre M, Owens P, Moses H, et al. TGFβ signaling in myeloid cells regulates mammary carcinoma cell invasion through fibroblast interactions. PLoS ONE. 2015;10:e0117908 pubmed publisher
  891. Chen Z, Shen H, Sun C, Yin L, Tang F, Zheng P, et al. Myeloid cell TRAF3 promotes metabolic inflammation, insulin resistance, and hepatic steatosis in obesity. Am J Physiol Endocrinol Metab. 2015;308:E460-9 pubmed publisher
  892. Lee E, Kim S, Cho K. Reconstituted High-Density Lipoprotein Containing Human Growth Hormone-1 Shows Potent Tissue Regeneration Activity with Enhancement of Anti-Oxidant and Anti-Atherosclerotic Activities. Rejuvenation Res. 2015;18:245-56 pubmed publisher
  893. Chandler R, Damrauer J, Raab J, Schisler J, Wilkerson M, Didion J, et al. Coexistent ARID1A-PIK3CA mutations promote ovarian clear-cell tumorigenesis through pro-tumorigenic inflammatory cytokine signalling. Nat Commun. 2015;6:6118 pubmed publisher
  894. Ammar A, Esmat A, Hassona M, Tadros M, Abdel Naim A, Guns E. The effect of pomegranate fruit extract on testosterone-induced BPH in rats. Prostate. 2015;75:679-92 pubmed publisher
  895. Verma R, Marchese A. The endosomal sorting complex required for transport pathway mediates chemokine receptor CXCR4-promoted lysosomal degradation of the mammalian target of rapamycin antagonist DEPTOR. J Biol Chem. 2015;290:6810-24 pubmed publisher
  896. López de Figueroa P, Lotz M, Blanco F, Caramés B. Autophagy activation and protection from mitochondrial dysfunction in human chondrocytes. Arthritis Rheumatol. 2015;67:966-76 pubmed publisher
  897. Niemeyer B, Parrish J, Spoelstra N, Joyal T, Richer J, Jedlicka P. Variable expression of PIK3R3 and PTEN in Ewing Sarcoma impacts oncogenic phenotypes. PLoS ONE. 2015;10:e0116895 pubmed publisher
  898. Buchner D, Charrier A, Srinivasan E, Wang L, Paulsen M, Ljungman M, et al. Zinc finger protein 407 (ZFP407) regulates insulin-stimulated glucose uptake and glucose transporter 4 (Glut4) mRNA. J Biol Chem. 2015;290:6376-86 pubmed publisher
  899. Peres J, Mowla S, Prince S. The T-box transcription factor, TBX3, is a key substrate of AKT3 in melanomagenesis. Oncotarget. 2015;6:1821-33 pubmed
  900. Yoo J, Kim T, Kong S, Lee J, Choi W, Kim K, et al. Role of Mig-6 in hepatic glucose metabolism. J Diabetes. 2016;8:86-97 pubmed publisher
  901. Kim S, Ebbert K, Cordeiro M, Romero M, Zhu J, Serna V, et al. Cell autonomous phosphoinositide 3-kinase activation in oocytes disrupts normal ovarian function through promoting survival and overgrowth of ovarian follicles. Endocrinology. 2015;156:1464-76 pubmed publisher
  902. Azimzadeh O, Sievert W, Sarioglu H, Merl Pham J, Yentrapalli R, Bakshi M, et al. Integrative proteomics and targeted transcriptomics analyses in cardiac endothelial cells unravel mechanisms of long-term radiation-induced vascular dysfunction. J Proteome Res. 2015;14:1203-19 pubmed publisher
  903. Blanchard Z, Paul B, Craft B, ElShamy W. BRCA1-IRIS inactivation overcomes paclitaxel resistance in triple negative breast cancers. Breast Cancer Res. 2015;17:5 pubmed publisher
  904. Wang S, Amato K, Song W, Youngblood V, Lee K, Boothby M, et al. Regulation of endothelial cell proliferation and vascular assembly through distinct mTORC2 signaling pathways. Mol Cell Biol. 2015;35:1299-313 pubmed publisher
  905. Zhou W, Ke S, Huang Z, Flavahan W, Fang X, Paul J, et al. Periostin secreted by glioblastoma stem cells recruits M2 tumour-associated macrophages and promotes malignant growth. Nat Cell Biol. 2015;17:170-82 pubmed publisher
  906. D Hulst G, Sylow L, Hespel P, Deldicque L. Acute systemic insulin intolerance does not alter the response of the Akt/GSK-3 pathway to environmental hypoxia in human skeletal muscle. Eur J Appl Physiol. 2015;115:1219-31 pubmed publisher
  907. Cheng Y, Chen P, Chiang H, Suen C, Hwang M, Lin T, et al. Candidate tumor suppressor B-cell translocation gene 3 impedes neoplastic progression by suppression of AKT. Cell Death Dis. 2015;6:e1584 pubmed publisher
  908. Sathyamurthy A, Yin D, Barik A, Shen C, Bean J, Figueiredo D, et al. ERBB3-mediated regulation of Bergmann glia proliferation in cerebellar lamination. Development. 2015;142:522-32 pubmed publisher
  909. Karner C, Esen E, Okunade A, Patterson B, Long F. Increased glutamine catabolism mediates bone anabolism in response to WNT signaling. J Clin Invest. 2015;125:551-62 pubmed publisher
  910. Shrestha S, Yang K, Guy C, Vogel P, Neale G, Chi H. Treg cells require the phosphatase PTEN to restrain TH1 and TFH cell responses. Nat Immunol. 2015;16:178-87 pubmed publisher
  911. Boj S, Hwang C, Baker L, Chio I, Engle D, Corbo V, et al. Organoid models of human and mouse ductal pancreatic cancer. Cell. 2015;160:324-38 pubmed publisher
  912. Zheng H, Fu J, Xue P, Zhao R, Dong J, Liu D, et al. CNC-bZIP protein Nrf1-dependent regulation of glucose-stimulated insulin secretion. Antioxid Redox Signal. 2015;22:819-31 pubmed publisher
  913. Rogers R, Beaudoin M, Wheatley J, Wright D, Geiger P. Heat shock proteins: in vivo heat treatments reveal adipose tissue depot-specific effects. J Appl Physiol (1985). 2015;118:98-106 pubmed publisher
  914. Mir S, George N, Zahoor L, Harms R, Guinn Z, SARVETNICK N. Inhibition of autophagic turnover in β-cells by fatty acids and glucose leads to apoptotic cell death. J Biol Chem. 2015;290:6071-85 pubmed publisher
  915. Chen C, Hung T, Lee C, Wang L, Wu C, Ke C, et al. Berberine protects against neuronal damage via suppression of glia-mediated inflammation in traumatic brain injury. PLoS ONE. 2014;9:e115694 pubmed publisher
  916. Lin T, Shih Y, Chen S, Lien C, Chang C, Huang T, et al. Running exercise delays neurodegeneration in amygdala and hippocampus of Alzheimer's disease (APP/PS1) transgenic mice. Neurobiol Learn Mem. 2015;118:189-97 pubmed publisher
  917. Azizi P, Zyla R, Guan S, Wang C, Liu J, Bolz S, et al. Clathrin-dependent entry and vesicle-mediated exocytosis define insulin transcytosis across microvascular endothelial cells. Mol Biol Cell. 2015;26:740-50 pubmed publisher
  918. Lee S, Lee K, Lee J, Kang S, Kim H, Asahara T, et al. Selective Interference Targeting of Lnk in Umbilical Cord-Derived Late Endothelial Progenitor Cells Improves Vascular Repair, Following Hind Limb Ischemic Injury, via Regulation of JAK2/STAT3 Signaling. Stem Cells. 2015;33:1490-500 pubmed publisher
  919. Zhang X, Cheng S, Bian K, Wang L, Zhang X, Yan B, et al. MicroRNA-26a promotes anoikis in human hepatocellular carcinoma cells by targeting alpha5 integrin. Oncotarget. 2015;6:2277-89 pubmed
  920. Ni H, Bhakta A, Wang S, Li Z, Manley S, Huang H, et al. Role of hypoxia inducing factor-1β in alcohol-induced autophagy, steatosis and liver injury in mice. PLoS ONE. 2014;9:e115849 pubmed publisher
  921. Cebulla J, Huuse E, Pettersen K, van der Veen A, Kim E, Andersen S, et al. MRI reveals the in vivo cellular and vascular response to BEZ235 in ovarian cancer xenografts with different PI3-kinase pathway activity. Br J Cancer. 2015;112:504-13 pubmed publisher
  922. Pino M, Verstraeten S. Tl(I) and Tl(III) alter the expression of EGF-dependent signals and cyclins required for pheochromocytoma (PC12) cell-cycle resumption and progression. J Appl Toxicol. 2015;35:952-69 pubmed publisher
  923. Fiorini C, Cordani M, Gotte G, Picone D, Donadelli M. Onconase induces autophagy sensitizing pancreatic cancer cells to gemcitabine and activates Akt/mTOR pathway in a ROS-dependent manner. Biochim Biophys Acta. 2015;1853:549-60 pubmed publisher
  924. Inaba J, McConnell E, Davis K. Lunasin sensitivity in non-small cell lung cancer cells is linked to suppression of integrin signaling and changes in histone acetylation. Int J Mol Sci. 2014;15:23705-24 pubmed publisher
  925. Zemany L, Bhanot S, Peroni O, Murray S, Moraes Vieira P, Castoldi A, et al. Transthyretin Antisense Oligonucleotides Lower Circulating RBP4 Levels and Improve Insulin Sensitivity in Obese Mice. Diabetes. 2015;64:1603-14 pubmed publisher
  926. Shao C, Ahmad N, Hodges K, Kuang S, Ratliff T, Liu X. Inhibition of polo-like kinase 1 (Plk1) enhances the antineoplastic activity of metformin in prostate cancer. J Biol Chem. 2015;290:2024-33 pubmed publisher
  927. Winkler M, Dib C, Ljubimov A, Saghizadeh M. Targeting miR-146a to treat delayed wound healing in human diabetic organ-cultured corneas. PLoS ONE. 2014;9:e114692 pubmed publisher
  928. Zhang H, Chen Y, Wadham C, McCaughan G, Keane F, Gorrell M. Dipeptidyl peptidase 9 subcellular localization and a role in cell adhesion involving focal adhesion kinase and paxillin. Biochim Biophys Acta. 2015;1853:470-80 pubmed publisher
  929. Yoda A, Adelmant G, Tamburini J, Chapuy B, Shindoh N, Yoda Y, et al. Mutations in G protein β subunits promote transformation and kinase inhibitor resistance. Nat Med. 2015;21:71-5 pubmed publisher
  930. Delloye Bourgeois C, Jacquier A, Charoy C, Reynaud F, Nawabi H, Thoinet K, et al. PlexinA1 is a new Slit receptor and mediates axon guidance function of Slit C-terminal fragments. Nat Neurosci. 2015;18:36-45 pubmed publisher
  931. Bisson J, Mills B, Paul Helt J, Zwaka T, Cohen E. Wnt5a and Wnt11 inhibit the canonical Wnt pathway and promote cardiac progenitor development via the Caspase-dependent degradation of AKT. Dev Biol. 2015;398:80-96 pubmed publisher
  932. Ozmen A, Unek G, Kipmen Korgun D, Cetinkaya B, Avcil Z, Korgun E. Glucocorticoid exposure altered angiogenic factor expression via Akt/mTOR pathway in rat placenta. Ann Anat. 2015;198:34-40 pubmed publisher
  933. Smithline Z, Nikonova A, Hensley H, Cai K, Egleston B, Proia D, et al. Inhibiting heat shock protein 90 (HSP90) limits the formation of liver cysts induced by conditional deletion of Pkd1 in mice. PLoS ONE. 2014;9:e114403 pubmed publisher
  934. Diesenberg K, Beerbaum M, Fink U, Schmieder P, Krauss M. SEPT9 negatively regulates ubiquitin-dependent downregulation of EGFR. J Cell Sci. 2015;128:397-407 pubmed publisher
  935. O Connell K, Guo W, Serra C, Beck M, Wachtman L, Hoggatt A, et al. The effects of an ActRIIb receptor Fc fusion protein ligand trap in juvenile simian immunodeficiency virus-infected rhesus macaques. FASEB J. 2015;29:1165-75 pubmed publisher
  936. Kettenbach A, Sano H, Keller S, Lienhard G, Gerber S. SPECHT - single-stage phosphopeptide enrichment and stable-isotope chemical tagging: quantitative phosphoproteomics of insulin action in muscle. J Proteomics. 2015;114:48-60 pubmed publisher
  937. Galinato M, Orio L, Mandyam C. Methamphetamine differentially affects BDNF and cell death factors in anatomically defined regions of the hippocampus. Neuroscience. 2015;286:97-108 pubmed publisher
  938. Carter E, Miron Buchacra G, Goldoni S, Danahay H, Westwick J, Watson M, et al. Phosphoinositide 3-kinase alpha-dependent regulation of branching morphogenesis in murine embryonic lung: evidence for a role in determining morphogenic properties of FGF7. PLoS ONE. 2014;9:e113555 pubmed publisher
  939. Gasser J, Inuzuka H, Lau A, Wei W, Beroukhim R, Toker A. SGK3 mediates INPP4B-dependent PI3K signaling in breast cancer. Mol Cell. 2014;56:595-607 pubmed publisher
  940. Park B, Cha S, Han B, Kim S. Angiotensin IV stimulates high atrial stretch-induced ANP secretion via insulin regulated aminopeptidase. Peptides. 2015;63:30-7 pubmed publisher
  941. Kapodistria K, Tsilibary E, Politis P, Moustardas P, Charonis A, Kitsiou P. Nephrin, a transmembrane protein, is involved in pancreatic beta-cell survival signaling. Mol Cell Endocrinol. 2015;400:112-28 pubmed publisher
  942. Saghizadeh M, Dib C, Brunken W, Ljubimov A. Normalization of wound healing and stem cell marker patterns in organ-cultured human diabetic corneas by gene therapy of limbal cells. Exp Eye Res. 2014;129:66-73 pubmed publisher
  943. Olayanju A, Copple I, Bryan H, Edge G, Sison R, Wong M, et al. Brusatol provokes a rapid and transient inhibition of Nrf2 signaling and sensitizes mammalian cells to chemical toxicity-implications for therapeutic targeting of Nrf2. Free Radic Biol Med. 2015;78:202-12 pubmed publisher
  944. Heynen G, Fonfara A, Bernards R. Resistance to targeted cancer drugs through hepatocyte growth factor signaling. Cell Cycle. 2014;13:3808-17 pubmed publisher
  945. Guzmán E, Maers K, Roberts J, Kemami Wangun H, Harmody D, Wright A. The marine natural product microsclerodermin A is a novel inhibitor of the nuclear factor kappa B and induces apoptosis in pancreatic cancer cells. Invest New Drugs. 2015;33:86-94 pubmed publisher
  946. Wu C, Hung T, Chen C, Ke C, Lee C, Wang P, et al. Post-injury treatment with 7,8-dihydroxyflavone, a TrkB receptor agonist, protects against experimental traumatic brain injury via PI3K/Akt signaling. PLoS ONE. 2014;9:e113397 pubmed publisher
  947. Hall J, Sun J, Slade J, Kintner J, Bambino M, Whittimore J, et al. Host nectin-1 is required for efficient Chlamydia trachomatis serovar E development. Front Cell Infect Microbiol. 2014;4:158 pubmed publisher
  948. Kim T, Jo S, Choi H, Park J, Kim M, Nojima H, et al. Identification of Creb3l4 as an essential negative regulator of adipogenesis. Cell Death Dis. 2014;5:e1527 pubmed publisher
  949. Huang L, Carney J, Cardona D, Counter C. Decreased tumorigenesis in mice with a Kras point mutation at C118. Nat Commun. 2014;5:5410 pubmed publisher
  950. Soga M, Ohashi A, Taniguchi M, Matsui T, Tsuda T. The di-peptide Trp-His activates AMP-activated protein kinase and enhances glucose uptake independently of insulin in L6 myotubes. FEBS Open Bio. 2014;4:898-904 pubmed publisher
  951. Pérez Alvarez M, Mateos L, Alonso A, Wandosell F. Estradiol and Progesterone Administration After pMCAO Stimulates the Neurological Recovery and Reduces the Detrimental Effect of Ischemia Mainly in Hippocampus. Mol Neurobiol. 2015;52:1690-1703 pubmed publisher
  952. Blair B, Wu X, Zahari M, Mohseni M, Cidado J, Wong H, et al. A phosphoproteomic screen demonstrates differential dependence on HER3 for MAP kinase pathway activation by distinct PIK3CA mutations. Proteomics. 2015;15:318-26 pubmed publisher
  953. Israeli Rosenberg S, Chen C, Li R, Deussen D, Niesman I, Okada H, et al. Caveolin modulates integrin function and mechanical activation in the cardiomyocyte. FASEB J. 2015;29:374-84 pubmed publisher
  954. Qin J, Rajaratnam R, Feng L, Salami J, Barber Rotenberg J, Domsic J, et al. Development of organometallic S6K1 inhibitors. J Med Chem. 2015;58:305-14 pubmed publisher
  955. Hong Y, Kim J, Pectasides E, Fox C, Hong S, Ma Q, et al. Src mutation induces acquired lapatinib resistance in ERBB2-amplified human gastroesophageal adenocarcinoma models. PLoS ONE. 2014;9:e109440 pubmed publisher
  956. Tan L, Wang J, Tanizaki J, Huang Z, Aref A, Rusan M, et al. Development of covalent inhibitors that can overcome resistance to first-generation FGFR kinase inhibitors. Proc Natl Acad Sci U S A. 2014;111:E4869-77 pubmed publisher
  957. Bing L, Wu J, Zhang J, Chen Y, Hong Z, Zu H. DHT inhibits the Aβ25-35-induced apoptosis by regulation of seladin-1, survivin, XIAP, bax, and bcl-xl expression through a rapid PI3-K/Akt signaling in C6 glial cell lines. Neurochem Res. 2015;40:41-8 pubmed publisher
  958. Bhattachariya A, Turczyńska K, Grossi M, Nordström I, Buckbinder L, Albinsson S, et al. PYK2 selectively mediates signals for growth versus differentiation in response to stretch of spontaneously active vascular smooth muscle. Physiol Rep. 2014;2: pubmed publisher
  959. Ye R, Holland W, Gordillo R, Wang M, Wang Q, Shao M, et al. Adiponectin is essential for lipid homeostasis and survival under insulin deficiency and promotes β-cell regeneration. elife. 2014;3: pubmed publisher
  960. Musazzi L, Seguini M, Mallei A, Treccani G, Pelizzari M, Tornese P, et al. Time-dependent activation of MAPK/Erk1/2 and Akt/GSK3 cascades: modulation by agomelatine. BMC Neurosci. 2014;15:119 pubmed publisher
  961. Souza R, Piedade W, Soares L, Souza P, Aguiar A, Vechetti Júnior I, et al. Aerobic exercise training prevents heart failure-induced skeletal muscle atrophy by anti-catabolic, but not anabolic actions. PLoS ONE. 2014;9:e110020 pubmed publisher
  962. Blaabjerg L, Christensen G, Matsumoto M, van der Meulen T, Huising M, Billestrup N, et al. CRFR1 activation protects against cytokine-induced β-cell death. J Mol Endocrinol. 2014;53:417-27 pubmed publisher
  963. Holland W, Chinn D, Lara P, Gandara D, Mack P. Effects of AKT inhibition on HGF-mediated erlotinib resistance in non-small cell lung cancer cell lines. J Cancer Res Clin Oncol. 2015;141:615-26 pubmed publisher
  964. Guerrouahen B, Pasquier J, Kaoud N, Maleki M, Beauchamp M, Yasmeen A, et al. Akt-activated endothelium constitutes the niche for residual disease and resistance to bevacizumab in ovarian cancer. Mol Cancer Ther. 2014;13:3123-36 pubmed publisher
  965. Kim S, Ahn S, Lee E, Kim S, Na K, Chae D, et al. Bilirubin activates transcription of HIF-1α in human proximal tubular cells cultured in the physiologic oxygen content. J Korean Med Sci. 2014;29 Suppl 2:S146-54 pubmed publisher
  966. Mössenböck K, Vegiopoulos A, Rose A, Sijmonsma T, Herzig S, Schafmeier T. Browning of white adipose tissue uncouples glucose uptake from insulin signaling. PLoS ONE. 2014;9:e110428 pubmed publisher
  967. Puig M, Lugo R, Gabasa M, Giménez A, Velásquez A, Galgoczy R, et al. Matrix stiffening and β1 integrin drive subtype-specific fibroblast accumulation in lung cancer. Mol Cancer Res. 2015;13:161-73 pubmed publisher
  968. Balbas M, Burgess M, Murali R, Wongvipat J, Skaggs B, Mundel P, et al. MAGI-2 scaffold protein is critical for kidney barrier function. Proc Natl Acad Sci U S A. 2014;111:14876-81 pubmed publisher
  969. Kannike K, Sepp M, Zuccato C, Cattaneo E, Timmusk T. Forkhead transcription factor FOXO3a levels are increased in Huntington disease because of overactivated positive autofeedback loop. J Biol Chem. 2014;289:32845-57 pubmed publisher
  970. Ledonne A, Nobili A, Latagliata E, Cavallucci V, Guatteo E, Puglisi Allegra S, et al. Neuregulin 1 signalling modulates mGluR1 function in mesencephalic dopaminergic neurons. Mol Psychiatry. 2015;20:959-73 pubmed publisher
  971. Portella A, Silveira P, Laureano D, Cardoso S, Bittencourt V, Noschang C, et al. Litter size reduction alters insulin signaling in the ventral tegmental area and influences dopamine-related behaviors in adult rats. Behav Brain Res. 2015;278:66-73 pubmed publisher
  972. Morioka T, Sakabe M, Ioka T, Iguchi T, Mizuta K, Hattammaru M, et al. An important role of endothelial hairy-related transcription factors in mouse vascular development. Genesis. 2014;52:897-906 pubmed publisher
  973. Peng M, Yin N, Li M. Sestrins function as guanine nucleotide dissociation inhibitors for Rag GTPases to control mTORC1 signaling. Cell. 2014;159:122-133 pubmed publisher
  974. Serizawa Y, Oshima R, Yoshida M, Sakon I, Kitani K, Goto A, et al. Salicylate acutely stimulates 5'-AMP-activated protein kinase and insulin-independent glucose transport in rat skeletal muscles. Biochem Biophys Res Commun. 2014;453:81-5 pubmed publisher
  975. Vanli G, Peltzer N, Dubuis G, Widmann C. The activity of the anti-apoptotic fragment generated by the caspase-3/p120 RasGAP stress-sensing module displays strict Akt isoform specificity. Cell Signal. 2014;26:2992-7 pubmed publisher
  976. Wang Y, Yang R, Gu J, Yin X, Jin N, Xie S, et al. Cross talk between PI3K-AKT-GSK-3β and PP2A pathways determines tau hyperphosphorylation. Neurobiol Aging. 2015;36:188-200 pubmed publisher
  977. Ritchie I, Wright D, Dyck D. Adiponectin is not required for exercise training-induced improvements in glucose and insulin tolerance in mice. Physiol Rep. 2014;2: pubmed publisher
  978. Sackmann Sala L, Chiche A, Mosquera Garrote N, Boutillon F, Cordier C, Pourmir I, et al. Prolactin-induced prostate tumorigenesis links sustained Stat5 signaling with the amplification of basal/stem cells and emergence of putative luminal progenitors. Am J Pathol. 2014;184:3105-19 pubmed publisher
  979. Rubashkin M, Cassereau L, Bainer R, DuFort C, Yui Y, Ou G, et al. Force engages vinculin and promotes tumor progression by enhancing PI3K activation of phosphatidylinositol (3,4,5)-triphosphate. Cancer Res. 2014;74:4597-611 pubmed publisher
  980. Oliveira C, de Bock C, Molloy T, Sadeqzadeh E, Geng X, Hersey P, et al. Macrophage migration inhibitory factor engages PI3K/Akt signalling and is a prognostic factor in metastatic melanoma. BMC Cancer. 2014;14:630 pubmed publisher
  981. Niu F, Yao H, Zhang W, Sutliff R, Buch S. Tat 101-mediated enhancement of brain pericyte migration involves platelet-derived growth factor subunit B homodimer: implications for human immunodeficiency virus-associated neurocognitive disorders. J Neurosci. 2014;34:11812-25 pubmed publisher
  982. Kleinert M, Sylow L, Fazakerley D, Krycer J, Thomas K, Oxbøll A, et al. Acute mTOR inhibition induces insulin resistance and alters substrate utilization in vivo. Mol Metab. 2014;3:630-41 pubmed publisher
  983. Kodama T, Motoi N, Ninomiya H, Sakamoto H, Kitada K, Tsukaguchi T, et al. A novel mechanism of EML4-ALK rearrangement mediated by chromothripsis in a patient-derived cell line. J Thorac Oncol. 2014;9:1638-46 pubmed publisher
  984. Osinalde N, Sánchez Quiles V, Akimov V, Guerra B, Blagoev B, Kratchmarova I. Simultaneous dissection and comparison of IL-2 and IL-15 signaling pathways by global quantitative phosphoproteomics. Proteomics. 2015;15:520-31 pubmed publisher
  985. Niu H, Nie L, Liu M, Chi Y, Zhang T, Li Y. Benazepril affects integrin-linked kinase and smooth muscle α-actin expression in diabetic rat glomerulus and cultured mesangial cells. BMC Nephrol. 2014;15:135 pubmed publisher
  986. Jung Y, Wang J, Lee E, McGee S, Berry J, Yumoto K, et al. Annexin 2-CXCL12 interactions regulate metastatic cell targeting and growth in the bone marrow. Mol Cancer Res. 2015;13:197-207 pubmed publisher
  987. Fuller S, Richard A, Ribnicky D, Beyl R, Mynatt R, Stephens J. St. John's Wort Has Metabolically Favorable Effects on Adipocytes In Vivo. Evid Based Complement Alternat Med. 2014;2014:862575 pubmed publisher
  988. Morris S, Carter K, Baek J, Koszarek A, Yeh M, Knoblaugh S, et al. TGF-? signaling alters the pattern of liver tumorigenesis induced by Pten inactivation. Oncogene. 2015;34:3273-82 pubmed publisher
  989. Tang S, Chen T, Yu Z, Zhu X, Yang M, Xie B, et al. RasGRP3 limits Toll-like receptor-triggered inflammatory response in macrophages by activating Rap1 small GTPase. Nat Commun. 2014;5:4657 pubmed publisher
  990. Curto G, Nieto Estévez V, Hurtado Chong A, Valero J, Gómez C, Alonso J, et al. Pax6 is essential for the maintenance and multi-lineage differentiation of neural stem cells, and for neuronal incorporation into the adult olfactory bulb. Stem Cells Dev. 2014;23:2813-30 pubmed publisher
  991. Tsai Y, Lai C, Lai C, Chang K, Wu K, Tseng S, et al. The role of homeostatic regulation between tumor suppressor DAB2IP and oncogenic Skp2 in prostate cancer growth. Oncotarget. 2014;5:6425-36 pubmed
  992. Selfridge J, Wilkins H, E L, Carl S, Koppel S, Funk E, et al. Effect of one month duration ketogenic and non-ketogenic high fat diets on mouse brain bioenergetic infrastructure. J Bioenerg Biomembr. 2015;47:1-11 pubmed publisher
  993. Baek J, Kim J, Cheon Y, Park S, Ahn S, Yoon K, et al. Aconitum pseudo-laeve var. erectum inhibits receptor activator of nuclear factor kappa-B ligand-induced osteoclastogenesis via the c-Fos/nuclear factor of activated T-cells, cytoplasmic 1 signaling pathway and prevents lipopolysaccharide-induced bone. Molecules. 2014;19:11628-44 pubmed publisher
  994. Bailon E, Ugarte Berzal E, Amigo Jiménez I, Van den Steen P, Opdenakker G, Garcia Marco J, et al. Overexpression of progelatinase B/proMMP-9 affects migration regulatory pathways and impairs chronic lymphocytic leukemia cell homing to bone marrow and spleen. J Leukoc Biol. 2014;96:185-99 pubmed publisher
  995. Tersey S, Maier B, Nishiki Y, Maganti A, Nadler J, Mirmira R. 12-lipoxygenase promotes obesity-induced oxidative stress in pancreatic islets. Mol Cell Biol. 2014;34:3735-45 pubmed publisher
  996. Wang F, Cai M, Mai S, Chen J, Bai H, Li Y, et al. Ablation of EIF5A2 induces tumor vasculature remodeling and improves tumor response to chemotherapy via regulation of matrix metalloproteinase 2 expression. Oncotarget. 2014;5:6716-33 pubmed
  997. Watanabe T, Nakamura S, Ono T, Ui S, Yagi S, Kagawa H, et al. Pyrrolidinium fullerene induces apoptosis by activation of procaspase-9 via suppression of Akt in primary effusion lymphoma. Biochem Biophys Res Commun. 2014;451:93-100 pubmed publisher
  998. Sidhu H, Dansie L, Hickmott P, Ethell D, Ethell I. Genetic removal of matrix metalloproteinase 9 rescues the symptoms of fragile X syndrome in a mouse model. J Neurosci. 2014;34:9867-79 pubmed publisher
  999. Zeldich E, Chen C, Colvin T, Bove Fenderson E, Liang J, Tucker Zhou T, et al. The neuroprotective effect of Klotho is mediated via regulation of members of the redox system. J Biol Chem. 2014;289:24700-15 pubmed publisher
  1000. Moorwood C, Philippou A, Spinazzola J, Keyser B, Macarak E, Barton E. Absence of ?-sarcoglycan alters the response of p70S6 kinase to mechanical perturbation in murine skeletal muscle. Skelet Muscle. 2014;4:13 pubmed publisher
  1001. Patel A, Burton D, Halvorsen K, Balkan W, Reiner T, Perez Stable C, et al. MutT Homolog 1 (MTH1) maintains multiple KRAS-driven pro-malignant pathways. Oncogene. 2015;34:2586-96 pubmed publisher
  1002. Hyde G, Taylor R, Ashton N, Borland S, Wu H, Gilmore A, et al. Axl tyrosine kinase protects against tubulo-interstitial apoptosis and progression of renal failure in a murine model of chronic kidney disease and hyperphosphataemia. PLoS ONE. 2014;9:e102096 pubmed publisher
  1003. Martin V, Corso S, Comoglio P, Giordano S. Increase of MET gene copy number confers resistance to a monovalent MET antibody and establishes drug dependence. Mol Oncol. 2014;8:1561-74 pubmed publisher
  1004. Yokota M, Kobayashi Y, Morita J, Suzuki H, Hashimoto Y, Sasaki Y, et al. Therapeutic effect of nanogel-based delivery of soluble FGFR2 with S252W mutation on craniosynostosis. PLoS ONE. 2014;9:e101693 pubmed publisher
  1005. Wang Y, Li W, Patel S, Cong J, Zhang N, Sabbatino F, et al. Blocking the formation of radiation-induced breast cancer stem cells. Oncotarget. 2014;5:3743-55 pubmed
  1006. Zaganjor E, Weil L, Gonzales J, Minna J, Cobb M. Ras transformation uncouples the kinesin-coordinated cellular nutrient response. Proc Natl Acad Sci U S A. 2014;111:10568-73 pubmed publisher
  1007. E L, Burns J, Swerdlow R. Effect of high-intensity exercise on aged mouse brain mitochondria, neurogenesis, and inflammation. Neurobiol Aging. 2014;35:2574-2583 pubmed publisher
  1008. Abildgaard J, Henstridge D, Pedersen A, Langley K, Scheele C, Pedersen B, et al. In vitro palmitate treatment of myotubes from postmenopausal women leads to ceramide accumulation, inflammation and affected insulin signaling. PLoS ONE. 2014;9:e101555 pubmed publisher
  1009. Li C, Chen J, Lu B, Shi Z, Wang H, Zhang B, et al. Molecular switch role of Akt in Polygonatum odoratum lectin-induced apoptosis and autophagy in human non-small cell lung cancer A549 cells. PLoS ONE. 2014;9:e101526 pubmed publisher
  1010. Zheng X, Zhai B, Koivunen P, Shin S, Lu G, Liu J, et al. Prolyl hydroxylation by EglN2 destabilizes FOXO3a by blocking its interaction with the USP9x deubiquitinase. Genes Dev. 2014;28:1429-44 pubmed publisher
  1011. Liu J, Ke F, Xu Z, Liu Z, Zhang L, Yan S, et al. CCR6 is a prognostic marker for overall survival in patients with colorectal cancer, and its overexpression enhances metastasis in vivo. PLoS ONE. 2014;9:e101137 pubmed publisher
  1012. Morris M, Gilliam E, Button J, Li L. Dynamic modulation of innate immune response by varying dosages of lipopolysaccharide (LPS) in human monocytic cells. J Biol Chem. 2014;289:21584-90 pubmed publisher
  1013. Paatero I, Seagroves T, Vaparanta K, Han W, Jones F, Johnson R, et al. Hypoxia-inducible factor-1? induces ErbB4 signaling in the differentiating mammary gland. J Biol Chem. 2014;289:22459-69 pubmed publisher
  1014. Hellesøy M, Blois A, Tiron C, Mannelqvist M, Akslen L, Lorens J. Akt1 activity regulates vessel maturation in a tissue engineering model of angiogenesis. Tissue Eng Part A. 2014;20:2590-603 pubmed publisher
  1015. Xu Y, Du H, Li J, Xu R, Wang Y, You S, et al. Statins upregulate cystathionine ?-lyase transcription and H2S generation via activating Akt signaling in macrophage. Pharmacol Res. 2014;87:18-25 pubmed publisher
  1016. Tanaka T, Iino M. Sec6 regulated cytoplasmic translocation and degradation of p27 via interactions with Jab1 and Siah1. Cell Signal. 2014;26:2071-85 pubmed publisher
  1017. Chen J, Long F. mTORC1 signaling controls mammalian skeletal growth through stimulation of protein synthesis. Development. 2014;141:2848-54 pubmed publisher
  1018. Lebron M, Brennan L, Damoci C, Prewett M, O Mahony M, Duignan I, et al. A human monoclonal antibody targeting the stem cell factor receptor (c-Kit) blocks tumor cell signaling and inhibits tumor growth. Cancer Biol Ther. 2014;15:1208-18 pubmed publisher
  1019. Moody S, Schinzel A, Singh S, Izzo F, Strickland M, Luo L, et al. PRKACA mediates resistance to HER2-targeted therapy in breast cancer cells and restores anti-apoptotic signaling. Oncogene. 2015;34:2061-71 pubmed publisher
  1020. Wang J, Mikse O, Liao R, Li Y, Tan L, Jänne P, et al. Ligand-associated ERBB2/3 activation confers acquired resistance to FGFR inhibition in FGFR3-dependent cancer cells. Oncogene. 2015;34:2167-77 pubmed publisher
  1021. Johnston Cox H, Eisenstein A, Koupenova M, Carroll S, Ravid K. The macrophage A2B adenosine receptor regulates tissue insulin sensitivity. PLoS ONE. 2014;9:e98775 pubmed publisher
  1022. Jung K, Wu F, Wang P, Ye X, Abdulkarim B, Lai R. YB-1 regulates Sox2 to coordinately sustain stemness and tumorigenic properties in a phenotypically distinct subset of breast cancer cells. BMC Cancer. 2014;14:328 pubmed publisher
  1023. Vélez E, Lutfi E, Jiménez Amilburu V, Riera Codina M, Capilla E, Navarro I, et al. IGF-I and amino acids effects through TOR signaling on proliferation and differentiation of gilthead sea bream cultured myocytes. Gen Comp Endocrinol. 2014;205:296-304 pubmed publisher
  1024. Wan Y, Yang Y, Leng Q, Lan B, Jia H, Liu Y, et al. Vav1 increases Bcl-2 expression by selective activation of Rac2-Akt in leukemia T cells. Cell Signal. 2014;26:2202-9 pubmed publisher
  1025. Godde N, Sheridan J, Smith L, Pearson H, Britt K, Galea R, et al. Scribble modulates the MAPK/Fra1 pathway to disrupt luminal and ductal integrity and suppress tumour formation in the mammary gland. PLoS Genet. 2014;10:e1004323 pubmed publisher
  1026. Chen K, Yang T, Wu C, Cheng C, Hsu S, Hung H, et al. Pemetrexed induces S-phase arrest and apoptosis via a deregulated activation of Akt signaling pathway. PLoS ONE. 2014;9:e97888 pubmed publisher
  1027. Barns M, Gondro C, Tellam R, Radley Crabb H, Grounds M, Shavlakadze T. Molecular analyses provide insight into mechanisms underlying sarcopenia and myofibre denervation in old skeletal muscles of mice. Int J Biochem Cell Biol. 2014;53:174-85 pubmed publisher
  1028. Chin R, Fu X, Pai M, Vergnes L, Hwang H, Deng G, et al. The metabolite ?-ketoglutarate extends lifespan by inhibiting ATP synthase and TOR. Nature. 2014;510:397-401 pubmed publisher
  1029. Stevenson C, de la Rosa G, Anderson C, Murphy P, Capece T, Kim M, et al. Essential role of Elmo1 in Dock2-dependent lymphocyte migration. J Immunol. 2014;192:6062-70 pubmed publisher
  1030. Jiang Y, Kou Z, Wu T, An W, Zhou R, Wang H, et al. Xist deficiency and disorders of X-inactivation in rabbit embryonic stem cells can be rescued by transcription-factor-mediated conversion. Stem Cells Dev. 2014;23:2283-96 pubmed publisher
  1031. Brown D, LASSEGUE B, Lee M, Zafari R, Long J, Saavedra H, et al. Poldip2 knockout results in perinatal lethality, reduced cellular growth and increased autophagy of mouse embryonic fibroblasts. PLoS ONE. 2014;9:e96657 pubmed publisher
  1032. Padiya R, Chowdhury D, Borkar R, Srinivas R, Pal Bhadra M, Banerjee S. Garlic attenuates cardiac oxidative stress via activation of PI3K/AKT/Nrf2-Keap1 pathway in fructose-fed diabetic rat. PLoS ONE. 2014;9:e94228 pubmed publisher
  1033. Jung S, Ohk J, Jeong D, Li C, Lee S, Duan J, et al. Distinct regulatory effect of the p34SEI-1 oncoprotein on cancer metastasis in HER2/neu-positive and -negative cells. Int J Oncol. 2014;45:189-96 pubmed publisher
  1034. Coomans de Brachène A, Bollaert E, Eijkelenboom A, de Rocca Serra A, van der Vos K, Burgering B, et al. The expression of the tumour suppressor HBP1 is down-regulated by growth factors via the PI3K/PKB/FOXO pathway. Biochem J. 2014;460:25-34 pubmed publisher
  1035. Hardman S, Hall D, Cabrera A, Hancock C, Thomson D. The effects of age and muscle contraction on AMPK activity and heterotrimer composition. Exp Gerontol. 2014;55:120-8 pubmed publisher
  1036. Liu B, Cao Y, Huizinga T, Hafler D, Toes R. TLR-mediated STAT3 and ERK activation controls IL-10 secretion by human B cells. Eur J Immunol. 2014;44:2121-9 pubmed publisher
  1037. Tobin G, Zhang J, Goodwin D, Stewart S, Xu L, Knapton A, et al. The role of eNOS phosphorylation in causing drug-induced vascular injury. Toxicol Pathol. 2014;42:709-24 pubmed publisher
  1038. Akkad H, Corpeno R, Larsson L. Masseter muscle myofibrillar protein synthesis and degradation in an experimental critical illness myopathy model. PLoS ONE. 2014;9:e92622 pubmed publisher
  1039. Lamprecht M, Morrison B. GPR30 activation is neither necessary nor sufficient for acute neuroprotection by 17?-estradiol after an ischemic injury in organotypic hippocampal slice cultures. Brain Res. 2014;1563:131-7 pubmed publisher
  1040. Flavin R, Pettersson A, Hendrickson W, Fiorentino M, Finn S, Kunz L, et al. SPINK1 protein expression and prostate cancer progression. Clin Cancer Res. 2014;20:4904-11 pubmed publisher
  1041. Glinskii O, Li F, Wilson L, Barnes S, Rittenhouse Olson K, Barchi J, et al. Endothelial integrin ?3?1 stabilizes carbohydrate-mediated tumor/endothelial cell adhesion and induces macromolecular signaling complex formation at the endothelial cell membrane. Oncotarget. 2014;5:1382-9 pubmed
  1042. Wahl S, McLane L, Bercury K, Macklin W, Wood T. Mammalian target of rapamycin promotes oligodendrocyte differentiation, initiation and extent of CNS myelination. J Neurosci. 2014;34:4453-65 pubmed publisher
  1043. Marquez E, Riera M, Pascual J, Soler M. Albumin inhibits the insulin-mediated ACE2 increase in cultured podocytes. Am J Physiol Renal Physiol. 2014;306:F1327-34 pubmed publisher
  1044. Chen W, Ho C, Chang Y, Chen H, Lin C, Ling T, et al. Cancer-associated fibroblasts regulate the plasticity of lung cancer stemness via paracrine signalling. Nat Commun. 2014;5:3472 pubmed publisher
  1045. Codeluppi S, Fernández Zafra T, Sandor K, Kjell J, Liu Q, Abrams M, et al. Interleukin-6 secretion by astrocytes is dynamically regulated by PI3K-mTOR-calcium signaling. PLoS ONE. 2014;9:e92649 pubmed publisher
  1046. Knubel K, Pernu B, Sufit A, Nelson S, Pierce A, Keating A. MerTK inhibition is a novel therapeutic approach for glioblastoma multiforme. Oncotarget. 2014;5:1338-51 pubmed
  1047. Zhang L, Castanaro C, Luan B, Yang K, Fan L, Fairhurst J, et al. ERBB3/HER2 signaling promotes resistance to EGFR blockade in head and neck and colorectal cancer models. Mol Cancer Ther. 2014;13:1345-55 pubmed publisher
  1048. Yu P, Laird A, Du X, Wu J, Won K, Yamaguchi K, et al. Characterization of the activity of the PI3K/mTOR inhibitor XL765 (SAR245409) in tumor models with diverse genetic alterations affecting the PI3K pathway. Mol Cancer Ther. 2014;13:1078-91 pubmed publisher
  1049. Wang H, Sun W, Ma J, Pan Y, Wang L, Zhang W. Polycystin-1 mediates mechanical strain-induced osteoblastic mechanoresponses via potentiation of intracellular calcium and Akt/?-catenin pathway. PLoS ONE. 2014;9:e91730 pubmed publisher
  1050. Bouchekioua Bouzaghou K, Poulard C, Rambaud J, Lavergne E, Hussein N, Billaud M, et al. LKB1 when associated with methylatedER? is a marker of bad prognosis in breast cancer. Int J Cancer. 2014;135:1307-18 pubmed publisher
  1051. Son J, Jeong H, Kim H, Kim Y, Lee E, Lee H, et al. Pelargonidin attenuates PDGF-BB-induced aortic smooth muscle cell proliferation and migration by direct inhibition of focal adhesion kinase. Biochem Pharmacol. 2014;89:236-45 pubmed publisher
  1052. Jo D, Kim J, Son J, Song N, Kim Y, Yu Y, et al. Anti-angiogenic effect of bare titanium dioxide nanoparticles on pathologic neovascularization without unbearable toxicity. Nanomedicine. 2014;10:1109-17 pubmed publisher
  1053. Mellor K, Varma U, Stapleton D, Delbridge L. Cardiomyocyte glycophagy is regulated by insulin and exposure to high extracellular glucose. Am J Physiol Heart Circ Physiol. 2014;306:H1240-5 pubmed publisher
  1054. Boin A, Couvelard A, Couderc C, Brito I, Filipescu D, Kalamarides M, et al. Proteomic screening identifies a YAP-driven signaling network linked to tumor cell proliferation in human schwannomas. Neuro Oncol. 2014;16:1196-209 pubmed publisher
  1055. Hu J, Lu J, Lian G, Zhang J, Hecht J, Sheen V. Filamin B regulates chondrocyte proliferation and differentiation through Cdk1 signaling. PLoS ONE. 2014;9:e89352 pubmed publisher
  1056. Chang P, Wang T, Chang Y, Chu C, Lee C, Hsu H, et al. Autophagy pathway is required for IL-6 induced neuroendocrine differentiation and chemoresistance of prostate cancer LNCaP cells. PLoS ONE. 2014;9:e88556 pubmed publisher
  1057. Yoon H, Choi Y, Song J, Do I, Kang S, Ko Y, et al. Targeted inhibition of FAK, PYK2 and BCL-XL synergistically enhances apoptosis in ovarian clear cell carcinoma cell lines. PLoS ONE. 2014;9:e88587 pubmed publisher
  1058. Park E, Kim B, Lee E, Chang E, Kim D, Choi S, et al. Targeting of receptor for advanced glycation end products suppresses cyst growth in polycystic kidney disease. J Biol Chem. 2014;289:9254-62 pubmed publisher
  1059. Solan J, Lampe P. Specific Cx43 phosphorylation events regulate gap junction turnover in vivo. FEBS Lett. 2014;588:1423-9 pubmed publisher
  1060. Tchetchelnitski V, Van Den Eijnden M, Schmidt F, Stoker A. Developmental co-expression and functional redundancy of tyrosine phosphatases with neurotrophin receptors in developing sensory neurons. Int J Dev Neurosci. 2014;34:48-59 pubmed publisher
  1061. Zhang Q, Pan Y, Wang R, Kang L, Xue Q, Wang X, et al. Quercetin inhibits AMPK/TXNIP activation and reduces inflammatory lesions to improve insulin signaling defect in the hypothalamus of high fructose-fed rats. J Nutr Biochem. 2014;25:420-8 pubmed publisher
  1062. Taniguchi R, Fukushima H, Osawa K, Maruyama T, Yasuda H, Weih F, et al. RelB-induced expression of Cot, an MAP3K family member, rescues RANKL-induced osteoclastogenesis in alymphoplasia mice by promoting NF-?B2 processing by IKK?. J Biol Chem. 2014;289:7349-61 pubmed publisher
  1063. Pavet V, Shlyakhtina Y, He T, Ceschin D, Kohonen P, Perala M, et al. Plasminogen activator urokinase expression reveals TRAIL responsiveness and supports fractional survival of cancer cells. Cell Death Dis. 2014;5:e1043 pubmed publisher
  1064. Xiang M, Birkbak N, Vafaizadeh V, Walker S, Yeh J, Liu S, et al. STAT3 induction of miR-146b forms a feedback loop to inhibit the NF-?B to IL-6 signaling axis and STAT3-driven cancer phenotypes. Sci Signal. 2014;7:ra11 pubmed publisher
  1065. Chen S, Otero Y, Mulligan K, Lundblad T, Williams P, McGuinness O. Liver, but not muscle, has an entrainable metabolic memory. PLoS ONE. 2014;9:e86164 pubmed publisher
  1066. Naudin C, Sirvent A, Leroy C, Larive R, Simon V, Pannequin J, et al. SLAP displays tumour suppressor functions in colorectal cancer via destabilization of the SRC substrate EPHA2. Nat Commun. 2014;5:3159 pubmed publisher
  1067. Massimino M, Consoli M, Mesuraca M, Stagno F, Tirrò E, Stella S, et al. IRF5 is a target of BCR-ABL kinase activity and reduces CML cell proliferation. Carcinogenesis. 2014;35:1132-43 pubmed publisher
  1068. Wadosky K, Rodriguez J, Hite R, Min J, Walton B, Willis M. Muscle RING finger-1 attenuates IGF-I-dependent cardiomyocyte hypertrophy by inhibiting JNK signaling. Am J Physiol Endocrinol Metab. 2014;306:E723-39 pubmed publisher
  1069. Jespersen J, Mikkelsen U, Nedergaard A, Thorlund J, Schjerling P, Suetta C, et al. Alterations in molecular muscle mass regulators after 8 days immobilizing Special Forces mission. Scand J Med Sci Sports. 2015;25:175-83 pubmed publisher
  1070. Groenendyk J, Michalak M. Disrupted WNT signaling in mouse embryonic stem cells in the absence of calreticulin. Stem Cell Rev. 2014;10:191-206 pubmed publisher
  1071. Zemljic Harpf A, Godoy J, Platoshyn O, Asfaw E, Busija A, Domenighetti A, et al. Vinculin directly binds zonula occludens-1 and is essential for stabilizing connexin-43-containing gap junctions in cardiac myocytes. J Cell Sci. 2014;127:1104-16 pubmed publisher
  1072. Ziegler A, Chidambaram S, Forbes B, Wood T, Levison S. Insulin-like growth factor-II (IGF-II) and IGF-II analogs with enhanced insulin receptor-a binding affinity promote neural stem cell expansion. J Biol Chem. 2014;289:4626-33 pubmed publisher
  1073. Maire C, Ramkissoon S, Hayashi M, Haidar S, Ramkissoon L, diTomaso E, et al. Pten loss in Olig2 expressing neural progenitor cells and oligodendrocytes leads to interneuron dysplasia and leukodystrophy. Stem Cells. 2014;32:313-26 pubmed publisher
  1074. Wheeler S, Hammond C, Jornayvaz F, Samuel V, Shulman G, Soroka C, et al. Ost?-/- mice exhibit altered expression of intestinal lipid absorption genes, resistance to age-related weight gain, and modestly improved insulin sensitivity. Am J Physiol Gastrointest Liver Physiol. 2014;306:G425-38 pubmed publisher
  1075. Borghgraef P, Menuet C, Theunis C, Louis J, Devijver H, Maurin H, et al. Increasing brain protein O-GlcNAc-ylation mitigates breathing defects and mortality of Tau.P301L mice. PLoS ONE. 2013;8:e84442 pubmed publisher
  1076. McGuire D, Rowse A, Li H, Peng B, Sestero C, Cashman K, et al. CD5 enhances Th17-cell differentiation by regulating IFN-? response and ROR?t localization. Eur J Immunol. 2014;44:1137-42 pubmed publisher
  1077. Balko J, Giltnane J, Wang K, Schwarz L, Young C, Cook R, et al. Molecular profiling of the residual disease of triple-negative breast cancers after neoadjuvant chemotherapy identifies actionable therapeutic targets. Cancer Discov. 2014;4:232-45 pubmed publisher
  1078. Wang W, Chen Y, Wang S, Hu N, Cao Z, Wang W, et al. PIASx? ligase enhances SUMO1 modification of PTEN protein as a SUMO E3 ligase. J Biol Chem. 2014;289:3217-30 pubmed publisher
  1079. Sahlberg S, Gustafsson A, Pendekanti P, Glimelius B, Stenerlow B. The influence of AKT isoforms on radiation sensitivity and DNA repair in colon cancer cell lines. Tumour Biol. 2014;35:3525-34 pubmed publisher
  1080. Shi L, Wang J, Ren J, Cheng Y, Ying R, Wu X, et al. KLRG1 impairs CD4+ T cell responses via p16ink4a and p27kip1 pathways: role in hepatitis B vaccine failure in individuals with hepatitis C virus infection. J Immunol. 2014;192:649-57 pubmed publisher
  1081. Tan S, Shui G, Zhou J, Shi Y, Huang J, Xia D, et al. Critical role of SCD1 in autophagy regulation via lipogenesis and lipid rafts-coupled AKT-FOXO1 signaling pathway. Autophagy. 2014;10:226-42 pubmed publisher
  1082. Yue X, Hariri D, Caballero B, Zhang S, Bartlett M, Kaut O, et al. Comparative study of the neurotrophic effects elicited by VEGF-B and GDNF in preclinical in vivo models of Parkinson's disease. Neuroscience. 2014;258:385-400 pubmed publisher
  1083. Wang Y, Briz V, Chishti A, Bi X, Baudry M. Distinct roles for ?-calpain and m-calpain in synaptic NMDAR-mediated neuroprotection and extrasynaptic NMDAR-mediated neurodegeneration. J Neurosci. 2013;33:18880-92 pubmed publisher
  1084. Zhang Y, Zhang X, Gao L, Liu Y, Jiang D, Chen K, et al. Growth/differentiation factor 1 alleviates pressure overload-induced cardiac hypertrophy and dysfunction. Biochim Biophys Acta. 2014;1842:232-44 pubmed publisher
  1085. Ashlin T, Buckley M, Salter R, Johnson J, Kwan A, Ramji D. The anti-atherogenic cytokine interleukin-33 inhibits the expression of a disintegrin and metalloproteinase with thrombospondin motifs-1, -4 and -5 in human macrophages: Requirement of extracellular signal-regulated kinase, c-Jun N-terminal kinase an. Int J Biochem Cell Biol. 2014;46:113-23 pubmed publisher
  1086. Wu J, Akkuratov E, Bai Y, Gaskill C, Askari A, Liu L. Cell signaling associated with Na(+)/K(+)-ATPase: activation of phosphatidylinositide 3-kinase IA/Akt by ouabain is independent of Src. Biochemistry. 2013;52:9059-67 pubmed publisher
  1087. Haws M, JARAMILLO T, Espinosa F, Widman A, Stuber G, Sparta D, et al. PTEN knockdown alters dendritic spine/protrusion morphology, not density. J Comp Neurol. 2014;522:1171-90 pubmed publisher
  1088. El Ami T, Moll L, Carvalhal Marques F, Volovik Y, Reuveni H, Cohen E. A novel inhibitor of the insulin/IGF signaling pathway protects from age-onset, neurodegeneration-linked proteotoxicity. Aging Cell. 2014;13:165-74 pubmed publisher
  1089. Wang J, Chen J, Miller D, Li W. Synergistic combination of novel tubulin inhibitor ABI-274 and vemurafenib overcome vemurafenib acquired resistance in BRAFV600E melanoma. Mol Cancer Ther. 2014;13:16-26 pubmed publisher
  1090. Treebak J, Pehmøller C, Kristensen J, Kjøbsted R, Birk J, Schjerling P, et al. Acute exercise and physiological insulin induce distinct phosphorylation signatures on TBC1D1 and TBC1D4 proteins in human skeletal muscle. J Physiol. 2014;592:351-75 pubmed publisher
  1091. Castorina A, Scuderi S, D Amico A, Drago F, D Agata V. PACAP and VIP increase the expression of myelin-related proteins in rat schwannoma cells: involvement of PAC1/VPAC2 receptor-mediated activation of PI3K/Akt signaling pathways. Exp Cell Res. 2014;322:108-21 pubmed publisher
  1092. Dunn C, Lampe P. Injury-triggered Akt phosphorylation of Cx43: a ZO-1-driven molecular switch that regulates gap junction size. J Cell Sci. 2014;127:455-64 pubmed publisher
  1093. Valtcheva N, Primorac A, Jurisic G, Hollmen M, Detmar M. The orphan adhesion G protein-coupled receptor GPR97 regulates migration of lymphatic endothelial cells via the small GTPases RhoA and Cdc42. J Biol Chem. 2013;288:35736-48 pubmed publisher
  1094. Chen Z, Morris D, Jiang L, Liu Y, Rui L. SH2B1 in ?-cells regulates glucose metabolism by promoting ?-cell survival and islet expansion. Diabetes. 2014;63:585-95 pubmed publisher
  1095. Udagawa T, Farny N, Jakovcevski M, Kaphzan H, Alarcon J, Anilkumar S, et al. Genetic and acute CPEB1 depletion ameliorate fragile X pathophysiology. Nat Med. 2013;19:1473-7 pubmed publisher
  1096. Bhaskar K, Maphis N, Xu G, Varvel N, Kokiko Cochran O, Weick J, et al. Microglial derived tumor necrosis factor-? drives Alzheimer's disease-related neuronal cell cycle events. Neurobiol Dis. 2014;62:273-85 pubmed publisher
  1097. Dai X, Jiang W, Zhang Q, Xu L, Geng P, Zhuang S, et al. Requirement for integrin-linked kinase in neural crest migration and differentiation and outflow tract morphogenesis. BMC Biol. 2013;11:107 pubmed publisher
  1098. Haas M, Onstead Haas L, Naem E, Arnold A, Rohrbaugh N, Flowers M, et al. The effect of black seed (Nigella sativa) extract on FOXO3 expression in HepG2 cells. Phytother Res. 2014;28:873-9 pubmed publisher
  1099. Ni H, Du K, You M, Ding W. Critical role of FoxO3a in alcohol-induced autophagy and hepatotoxicity. Am J Pathol. 2013;183:1815-1825 pubmed publisher
  1100. Ishikawa K, Yoshida S, Nakao S, Nakama T, Kita T, Asato R, et al. Periostin promotes the generation of fibrous membranes in proliferative vitreoretinopathy. FASEB J. 2014;28:131-42 pubmed publisher
  1101. Paugh B, Zhu X, Qu C, Endersby R, Diaz A, Zhang J, et al. Novel oncogenic PDGFRA mutations in pediatric high-grade gliomas. Cancer Res. 2013;73:6219-29 pubmed publisher
  1102. Sáinz Jaspeado M, Huertas Martínez J, Lagares Tena L, Martín Liberal J, Mateo Lozano S, de Alava E, et al. EphA2-induced angiogenesis in ewing sarcoma cells works through bFGF production and is dependent on caveolin-1. PLoS ONE. 2013;8:e71449 pubmed publisher
  1103. Kucherlapati M, Esfahani S, Habibollahi P, Wang J, Still E, Bronson R, et al. Genotype directed therapy in murine mismatch repair deficient tumors. PLoS ONE. 2013;8:e68817 pubmed publisher
  1104. Yu P, Yan M, Lai H, Huang R, Chou Y, Lin W, et al. Downregulation of miR-29 contributes to cisplatin resistance of ovarian cancer cells. Int J Cancer. 2014;134:542-51 pubmed publisher
  1105. Dokas J, Chadt A, Nolden T, Himmelbauer H, Zierath J, Joost H, et al. Conventional knockout of Tbc1d1 in mice impairs insulin- and AICAR-stimulated glucose uptake in skeletal muscle. Endocrinology. 2013;154:3502-14 pubmed publisher
  1106. Zhang Y, Liu X, Han L, Gao X, Liu E, Wang T. Regulation of lipid and glucose homeostasis by mango tree leaf extract is mediated by AMPK and PI3K/AKT signaling pathways. Food Chem. 2013;141:2896-905 pubmed publisher
  1107. Elliott S, Swift S, Busse L, Scully S, Van G, Rossi J, et al. Epo receptors are not detectable in primary human tumor tissue samples. PLoS ONE. 2013;8:e68083 pubmed publisher
  1108. Hauerslev S, Sveen M, Vissing J, Krag T. Protein turnover and cellular stress in mildly and severely affected muscles from patients with limb girdle muscular dystrophy type 2I. PLoS ONE. 2013;8:e66929 pubmed publisher
  1109. Eguchi J, Kong X, Tenta M, Wang X, Kang S, Rosen E. Interferon regulatory factor 4 regulates obesity-induced inflammation through regulation of adipose tissue macrophage polarization. Diabetes. 2013;62:3394-403 pubmed publisher
  1110. Pulinilkunnil T, Kienesberger P, Nagendran J, Sharma N, Young M, Dyck J. Cardiac-specific adipose triglyceride lipase overexpression protects from cardiac steatosis and dilated cardiomyopathy following diet-induced obesity. Int J Obes (Lond). 2014;38:205-15 pubmed publisher
  1111. Chang A, Huang J, Battiprolu P, Hill J, Kamm K, Stull J. The effects of neuregulin on cardiac Myosin light chain kinase gene-ablated hearts. PLoS ONE. 2013;8:e66720 pubmed publisher
  1112. Brouxhon S, Kyrkanides S, Teng X, O Banion M, Clarke R, Byers S, et al. Soluble-E-cadherin activates HER and IAP family members in HER2+ and TNBC human breast cancers. Mol Carcinog. 2014;53:893-906 pubmed publisher
  1113. Mietzsch U, McKenna J, Reith R, Way S, Gambello M. Comparative analysis of Tsc1 and Tsc2 single and double radial glial cell mutants. J Comp Neurol. 2013;521:3817-31 pubmed publisher
  1114. Griffeth R, Carretero J, Burks D. Insulin receptor substrate 2 is required for testicular development. PLoS ONE. 2013;8:e62103 pubmed publisher
  1115. Beckham T, Cheng J, Lu P, Shao Y, Troyer D, Lance R, et al. Acid ceramidase induces sphingosine kinase 1/S1P receptor 2-mediated activation of oncogenic Akt signaling. Oncogenesis. 2013;2:e49 pubmed publisher
  1116. Zhou D, Tan R, Lin L, Zhou L, Liu Y. Activation of hepatocyte growth factor receptor, c-met, in renal tubules is required for renoprotection after acute kidney injury. Kidney Int. 2013;84:509-20 pubmed publisher
  1117. Liang H, Hussey S, Sanchez Avila A, Tantiwong P, Musi N. Effect of lipopolysaccharide on inflammation and insulin action in human muscle. PLoS ONE. 2013;8:e63983 pubmed publisher
  1118. Ma T, Galimberti F, Erkmen C, Memoli V, Chinyengetere F, SEMPERE L, et al. Comparing histone deacetylase inhibitor responses in genetically engineered mouse lung cancer models and a window of opportunity trial in patients with lung cancer. Mol Cancer Ther. 2013;12:1545-55 pubmed publisher
  1119. Gokhale N, Zaremba A, Janoshazi A, Weaver J, Shears S. PPIP5K1 modulates ligand competition between diphosphoinositol polyphosphates and PtdIns(3,4,5)P3 for polyphosphoinositide-binding domains. Biochem J. 2013;453:413-26 pubmed publisher
  1120. Wang Y, Zhao X, Shi D, Chen P, Yu Y, Yang L, et al. Overexpression of SIRT1 promotes high glucose-attenuated corneal epithelial wound healing via p53 regulation of the IGFBP3/IGF-1R/AKT pathway. Invest Ophthalmol Vis Sci. 2013;54:3806-14 pubmed publisher
  1121. Lessard S, Rivas D, Alves Wagner A, Hirshman M, Gallagher I, Constantin Teodosiu D, et al. Resistance to aerobic exercise training causes metabolic dysfunction and reveals novel exercise-regulated signaling networks. Diabetes. 2013;62:2717-27 pubmed publisher
  1122. Yu M, Trobridge P, Wang Y, Kanngurn S, Morris S, Knoblaugh S, et al. Inactivation of TGF-? signaling and loss of PTEN cooperate to induce colon cancer in vivo. Oncogene. 2014;33:1538-47 pubmed publisher
  1123. Tokami H, Ago T, Sugimori H, Kuroda J, Awano H, Suzuki K, et al. RANTES has a potential to play a neuroprotective role in an autocrine/paracrine manner after ischemic stroke. Brain Res. 2013;1517:122-32 pubmed publisher
  1124. Bauckman K, Haller E, Flores I, Nanjundan M. Iron modulates cell survival in a Ras- and MAPK-dependent manner in ovarian cells. Cell Death Dis. 2013;4:e592 pubmed publisher
  1125. Backman L, Danielson P. Akt-mediated anti-apoptotic effects of substance P in Anti-Fas-induced apoptosis of human tenocytes. J Cell Mol Med. 2013;17:723-33 pubmed publisher
  1126. Chu I, Lai W, Aprelikova O, El Touny L, Kouros Mehr H, Green J. Expression of GATA3 in MDA-MB-231 triple-negative breast cancer cells induces a growth inhibitory response to TGFß. PLoS ONE. 2013;8:e61125 pubmed publisher
  1127. Willis M, Min J, Wang S, McDonough H, Lockyer P, Wadosky K, et al. Carboxyl terminus of Hsp70-interacting protein (CHIP) is required to modulate cardiac hypertrophy and attenuate autophagy during exercise. Cell Biochem Funct. 2013;31:724-35 pubmed publisher
  1128. Haeussler D, Pimentel D, Hou X, Burgoyne J, Cohen R, Bachschmid M. Endomembrane H-Ras controls vascular endothelial growth factor-induced nitric-oxide synthase-mediated endothelial cell migration. J Biol Chem. 2013;288:15380-9 pubmed publisher
  1129. Ni M, Chen Y, Fei T, Li D, Lim E, Liu X, et al. Amplitude modulation of androgen signaling by c-MYC. Genes Dev. 2013;27:734-48 pubmed publisher
  1130. Liang H, Tantiwong P, Sriwijitkamol A, Shanmugasundaram K, Mohan S, Espinoza S, et al. Effect of a sustained reduction in plasma free fatty acid concentration on insulin signalling and inflammation in skeletal muscle from human subjects. J Physiol. 2013;591:2897-909 pubmed publisher
  1131. BENTLEY C, Jurinka S, Kljavin N, Vartanian S, Ramani S, Gonzalez L, et al. A requirement for wild-type Ras isoforms in mutant KRas-driven signalling and transformation. Biochem J. 2013;452:313-20 pubmed publisher
  1132. Areta J, Burke L, Ross M, Camera D, West D, Broad E, et al. Timing and distribution of protein ingestion during prolonged recovery from resistance exercise alters myofibrillar protein synthesis. J Physiol. 2013;591:2319-31 pubmed publisher
  1133. Kim H, Woo H, Ryu J, Bok J, Kim J, Choi S, et al. Conditional deletion of pten leads to defects in nerve innervation and neuronal survival in inner ear development. PLoS ONE. 2013;8:e55609 pubmed publisher
  1134. Dai J, Shen D, Bian Z, Zhou H, Gan H, Zong J, et al. IKKi deficiency promotes pressure overload-induced cardiac hypertrophy and fibrosis. PLoS ONE. 2013;8:e53412 pubmed publisher
  1135. Carra E, Barbieri F, Marubbi D, Pattarozzi A, Favoni R, Florio T, et al. Sorafenib selectively depletes human glioblastoma tumor-initiating cells from primary cultures. Cell Cycle. 2013;12:491-500 pubmed publisher
  1136. Suetta C, Frandsen U, Jensen L, Jensen M, Jespersen J, Hvid L, et al. Aging affects the transcriptional regulation of human skeletal muscle disuse atrophy. PLoS ONE. 2012;7:e51238 pubmed publisher
  1137. Danielson L, Park D, Rotllan N, Chamorro Jorganes A, Guijarro M, Fernandez Hernando C, et al. Cardiovascular dysregulation of miR-17-92 causes a lethal hypertrophic cardiomyopathy and arrhythmogenesis. FASEB J. 2013;27:1460-7 pubmed publisher
  1138. Sánchez Alvarez R, Martinez Outschoorn U, Lin Z, Lamb R, Hulit J, Howell A, et al. Ethanol exposure induces the cancer-associated fibroblast phenotype and lethal tumor metabolism: implications for breast cancer prevention. Cell Cycle. 2013;12:289-301 pubmed publisher
  1139. Wang I, Allen M, Goffin D, Zhu X, Fairless A, Brodkin E, et al. Loss of CDKL5 disrupts kinome profile and event-related potentials leading to autistic-like phenotypes in mice. Proc Natl Acad Sci U S A. 2012;109:21516-21 pubmed publisher
  1140. Fan C, Lum M, Xu C, Black J, Wang X. Ubiquitin-dependent regulation of phospho-AKT dynamics by the ubiquitin E3 ligase, NEDD4-1, in the insulin-like growth factor-1 response. J Biol Chem. 2013;288:1674-84 pubmed publisher
  1141. Vartanian S, BENTLEY C, Brauer M, Li L, Shirasawa S, Sasazuki T, et al. Identification of mutant K-Ras-dependent phenotypes using a panel of isogenic cell lines. J Biol Chem. 2013;288:2403-13 pubmed publisher
  1142. Kodigepalli K, Dutta P, Bauckman K, Nanjundan M. SnoN/SkiL expression is modulated via arsenic trioxide-induced activation of the PI3K/AKT pathway in ovarian cancer cells. FEBS Lett. 2013;587:5-16 pubmed publisher
  1143. van der Hoeven D, Cho K, Ma X, Chigurupati S, Parton R, Hancock J. Fendiline inhibits K-Ras plasma membrane localization and blocks K-Ras signal transmission. Mol Cell Biol. 2013;33:237-51 pubmed publisher
  1144. Cho K, Park J, Piggott A, Salim A, Gorfe A, Parton R, et al. Staurosporines disrupt phosphatidylserine trafficking and mislocalize Ras proteins. J Biol Chem. 2012;287:43573-84 pubmed publisher
  1145. Wang H, Ducommun S, Quan C, Xie B, Li M, Wasserman D, et al. AS160 deficiency causes whole-body insulin resistance via composite effects in multiple tissues. Biochem J. 2013;449:479-89 pubmed publisher
  1146. Schweitzer G, Arias E, Cartee G. Sustained postexercise increases in AS160 Thr642 and Ser588 phosphorylation in skeletal muscle without sustained increases in kinase phosphorylation. J Appl Physiol (1985). 2012;113:1852-61 pubmed publisher
  1147. Chatain N, Ziegler P, Fahrenkamp D, Jost E, Moriggl R, Schmitz Van de Leur H, et al. Src family kinases mediate cytoplasmic retention of activated STAT5 in BCR-ABL-positive cells. Oncogene. 2013;32:3587-97 pubmed publisher
  1148. Riaz A, Zeller K, Johansson S. Receptor-specific mechanisms regulate phosphorylation of AKT at Ser473: role of RICTOR in ?1 integrin-mediated cell survival. PLoS ONE. 2012;7:e32081 pubmed publisher
  1149. O Brien T, Gorentla B, Xie D, Srivatsan S, McLeod I, He Y, et al. Regulation of T-cell survival and mitochondrial homeostasis by TSC1. Eur J Immunol. 2011;41:3361-70 pubmed publisher
  1150. Li J, Swope D, Raess N, Cheng L, Muller E, Radice G. Cardiac tissue-restricted deletion of plakoglobin results in progressive cardiomyopathy and activation of {beta}-catenin signaling. Mol Cell Biol. 2011;31:1134-44 pubmed publisher
  1151. Modi H, Li L, Chu S, Rossi J, Yee J, Bhatia R. Inhibition of Grb2 expression demonstrates an important role in BCR-ABL-mediated MAPK activation and transformation of primary human hematopoietic cells. Leukemia. 2011;25:305-12 pubmed publisher
  1152. Son J, Varadarajan S, Bratton S. TRAIL-activated stress kinases suppress apoptosis through transcriptional upregulation of MCL-1. Cell Death Differ. 2010;17:1288-301 pubmed publisher
  1153. Udelhoven M, Pasieka M, Leeser U, Krone W, Schubert M. Neuronal insulin receptor substrate 2 (IRS2) expression is regulated by ZBP89 and SP1 binding to the IRS2 promoter. J Endocrinol. 2010;204:199-208 pubmed publisher