This is a Validated Antibody Database (VAD) review about chimpanzee LOC457457, based on 37 published articles (read how Labome selects the articles), using LOC457457 antibody in all methods. It is aimed to help Labome visitors find the most suited LOC457457 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
LOC457457 synonym: FCGR3A; low affinity immunoglobulin gamma Fc region receptor III-A; Fc fragment of IgG, low affinity IIIa, receptor (CD16a)

BioLegend
mouse monoclonal (3G8)
  • flow cytometry; human; loading ...; fig 2a
BioLegend LOC457457 antibody (Biolegend, 302035) was used in flow cytometry on human samples (fig 2a). elife (2019) ncbi
mouse monoclonal (3G8)
  • flow cytometry; human; loading ...; fig 1c
BioLegend LOC457457 antibody (BioLegend, 302025) was used in flow cytometry on human samples (fig 1c). J Exp Med (2018) ncbi
mouse monoclonal (3G8)
  • flow cytometry; human; loading ...; fig 1a
BioLegend LOC457457 antibody (Biolegend, 302002) was used in flow cytometry on human samples (fig 1a). Cell (2018) ncbi
mouse monoclonal (3G8)
  • flow cytometry; human; loading ...; fig 7c
In order to study the role of leukocyte antigen F in and antigen presentation and immune response, BioLegend LOC457457 antibody (BioLegend, 302040) was used in flow cytometry on human samples (fig 7c). Immunity (2017) ncbi
mouse monoclonal (3G8)
  • flow cytometry; Rhesus monkey; loading ...; fig 7a
In order to study the efficacy of nanoparticle adjuvants for inducing protective immunity against simian immunodeficiency virus, BioLegend LOC457457 antibody (Biolegend, 3G8) was used in flow cytometry on Rhesus monkey samples (fig 7a). J Virol (2017) ncbi
mouse monoclonal (3G8)
  • flow cytometry; human; loading ...; fig 1a
In order to investigate the roles of CD16+ monocytes in T-cell activation and B-cell responses in systemic lupus erythematosus, BioLegend LOC457457 antibody (Biolegend, 302012) was used in flow cytometry on human samples (fig 1a). Front Immunol (2016) ncbi
mouse monoclonal (3G8)
  • flow cytometry; human; loading ...; fig 1c
In order to profile the infiltration levels of immune cell populations in 19 cancer types, BioLegend LOC457457 antibody (Biolegend, 302008) was used in flow cytometry on human samples (fig 1c). Genome Biol (2016) ncbi
mouse monoclonal (3G8)
BioLegend LOC457457 antibody (BioLegend, 302006) was used . Nat Commun (2016) ncbi
mouse monoclonal (3G8)
  • flow cytometry; human; loading ...
In order to study the cytolytic effector capacity of HIV-specific CD8+ T cells, BioLegend LOC457457 antibody (Biolegend, 3G8) was used in flow cytometry on human samples . PLoS Pathog (2016) ncbi
mouse monoclonal (3G8)
  • flow cytometry; human; 1:100; fig 5
BioLegend LOC457457 antibody (Biolegend, 302007) was used in flow cytometry on human samples at 1:100 (fig 5). Nat Commun (2016) ncbi
mouse monoclonal (3G8)
  • flow cytometry; mouse; 1:200
In order to assess the role of NLRC5 to NK-T-cell crosstalk, BioLegend LOC457457 antibody (BioLegend, 3G8) was used in flow cytometry on mouse samples at 1:200. Nat Commun (2016) ncbi
mouse monoclonal (3G8)
  • flow cytometry; human; fig 5
BioLegend LOC457457 antibody (BioLegend, 3G8) was used in flow cytometry on human samples (fig 5). PLoS Pathog (2015) ncbi
mouse monoclonal (3G8)
  • flow cytometry; human; fig 7
BioLegend LOC457457 antibody (Biolegend, 3G8) was used in flow cytometry on human samples (fig 7). Eur J Immunol (2016) ncbi
mouse monoclonal (3G8)
  • flow cytometry; human; loading ...; fig s1b
In order to study age-related changes in human immunity during a primary virus infection experimentally induced by immunization with live-attenuated yellow fever vaccine, BioLegend LOC457457 antibody (Biolegend, 3G8) was used in flow cytometry on human samples (fig s1b). J Immunol (2015) ncbi
mouse monoclonal (3G8)
  • flow cytometry; human
BioLegend LOC457457 antibody (Biolegend, 302008) was used in flow cytometry on human samples . J Neuroimmunol (2015) ncbi
mouse monoclonal (3G8)
  • flow cytometry; mouse
In order to compare the initial systemic Env-specific B cell responses of AGMs and rhesus macaques, BioLegend LOC457457 antibody (Biolegend, 3G8) was used in flow cytometry on mouse samples . J Virol (2015) ncbi
mouse monoclonal (3G8)
  • flow cytometry; human; fig s3
In order to determine the competitive advantage for human hematopoietic stem cells in vivo provided by CCND1-CDK4-mediated cell cycle progression, BioLegend LOC457457 antibody (BioLegend, 3G8) was used in flow cytometry on human samples (fig s3). J Exp Med (2015) ncbi
mouse monoclonal (3G8)
  • flow cytometry; human; fig 1
In order to identify the response to anti-MPO antibodies in the form of increased surface expression of ANCA autoantigens and IL-1beta secretion acting as intermediate monocytes in ANCA vasculitis, BioLegend LOC457457 antibody (Biolegend, 3G8) was used in flow cytometry on human samples (fig 1). Sci Rep (2015) ncbi
mouse monoclonal (3G8)
  • flow cytometry; human
BioLegend LOC457457 antibody (BioLegend, 302026) was used in flow cytometry on human samples . PLoS ONE (2015) ncbi
mouse monoclonal (3G8)
  • flow cytometry; Rhesus monkey; fig 3
In order to elucidate how CD8 positive T cells suppress virus replication during simian immunodeficiency virus infection, BioLegend LOC457457 antibody (BioLegend, 3G8) was used in flow cytometry on Rhesus monkey samples (fig 3). J Virol (2015) ncbi
mouse monoclonal (3G8)
  • flow cytometry; human; fig 4
BioLegend LOC457457 antibody (Biolegend, 3G8) was used in flow cytometry on human samples (fig 4). J Rheumatol (2015) ncbi
mouse monoclonal (3G8)
  • flow cytometry; human; fig 1
BioLegend LOC457457 antibody (BioLegend, 3G8) was used in flow cytometry on human samples (fig 1). J Immunol (2015) ncbi
mouse monoclonal (3G8)
  • flow cytometry; human; fig 7
BioLegend LOC457457 antibody (BioLegend, 3G8) was used in flow cytometry on human samples (fig 7). J Immunol (2015) ncbi
mouse monoclonal (3G8)
  • flow cytometry; human
BioLegend LOC457457 antibody (BioLegend, 3G8) was used in flow cytometry on human samples . Genes Immun (2015) ncbi
mouse monoclonal (3G8)
  • flow cytometry; human
BioLegend LOC457457 antibody (Biolegend, 3G8) was used in flow cytometry on human samples . PLoS ONE (2014) ncbi
mouse monoclonal (3G8)
  • flow cytometry; human
In order to evaluate immune responses by monocyte isolated from young and old adults before and after influenza vaccination, BioLegend LOC457457 antibody (BioLegend, clone3G8) was used in flow cytometry on human samples . J Infect Dis (2015) ncbi
mouse monoclonal (3G8)
  • flow cytometry; Rhesus monkey
  • immunohistochemistry; Rhesus monkey
In order to examine the diagnostic value of mannose receptor CD206 in HIV and simian immunodeficiency virus encephalitis, BioLegend LOC457457 antibody (BioLegend, 3G8) was used in flow cytometry on Rhesus monkey samples and in immunohistochemistry on Rhesus monkey samples . J Neuroimmune Pharmacol (2014) ncbi
mouse monoclonal (3G8)
  • flow cytometry; human
BioLegend LOC457457 antibody (BioLegend, 3G8) was used in flow cytometry on human samples . Cell Immunol (2014) ncbi
mouse monoclonal (3G8)
  • flow cytometry; human
In order to determine the presence, frequency, association to other immune parameters, and functional properties of circulating CD14(+) cells lacking HLA-DR expression in patients with untreated chronic lymphocytic leukemia, BioLegend LOC457457 antibody (Biolegend, 3G8) was used in flow cytometry on human samples . Blood (2014) ncbi
mouse monoclonal (3G8)
  • flow cytometry; human
BioLegend LOC457457 antibody (BioLegend, 3G8) was used in flow cytometry on human samples . J Infect Dis (2014) ncbi
mouse monoclonal (3G8)
  • flow cytometry; human
BioLegend LOC457457 antibody (BioLegend, 3G8) was used in flow cytometry on human samples . PLoS Pathog (2014) ncbi
mouse monoclonal (3G8)
  • immunohistochemistry - frozen section; Rhesus monkey; loading ...
BioLegend LOC457457 antibody (BioLegend, 302005) was used in immunohistochemistry - frozen section on Rhesus monkey samples . Mol Ther (2014) ncbi
mouse monoclonal (3G8)
  • flow cytometry; human
BioLegend LOC457457 antibody (BioLegend, 3G8) was used in flow cytometry on human samples . Clin Cancer Res (2013) ncbi
mouse monoclonal (3G8)
  • flow cytometry; human
In order to describe protocols for immunostaining and multiparameter flow cytometric analysis of major human antigen-presenting cells in peripheral blood, BioLegend LOC457457 antibody (BioLegend, 302021) was used in flow cytometry on human samples . Nat Protoc (2010) ncbi
Invitrogen
mouse monoclonal (3G8)
  • flow cytometry; Rhesus monkey; tbl 1
In order to characterize the role of T-cell depletion and macrophage polarization and infection during splenic damage during SIV infection, Invitrogen LOC457457 antibody (eBioScience, 3G8) was used in flow cytometry on Rhesus monkey samples (tbl 1). Am J Pathol (2016) ncbi
mouse monoclonal (3G8)
  • immunoprecipitation; human
Invitrogen LOC457457 antibody (eBioscience, 3G8) was used in immunoprecipitation on human samples . J Biol Chem (2015) ncbi
mouse monoclonal (3G8)
  • flow cytometry; human; fig 8
In order to explore the role of HIV in potentially modulating macrophage function, Invitrogen LOC457457 antibody (eBioscience, 3G8) was used in flow cytometry on human samples (fig 8). Retrovirology (2013) ncbi
Articles Reviewed
  1. Dosch M, Zindel J, Jebbawi F, Melin N, Sánchez Taltavull D, Stroka D, et al. Connexin-43-dependent ATP release mediates macrophage activation during sepsis. elife. 2019;8: pubmed publisher
  2. Kelly A, Günaltay S, McEntee C, Shuttleworth E, Smedley C, Houston S, et al. Human monocytes and macrophages regulate immune tolerance via integrin αvβ8-mediated TGFβ activation. J Exp Med. 2018;215:2725-2736 pubmed publisher
  3. Olin A, Henckel E, Chen Y, Lakshmikanth T, Pou C, Mikes J, et al. Stereotypic Immune System Development in Newborn Children. Cell. 2018;174:1277-1292.e14 pubmed publisher
  4. Dulberger C, McMurtrey C, Hölzemer A, Neu K, Liu V, Steinbach A, et al. Human Leukocyte Antigen F Presents Peptides and Regulates Immunity through Interactions with NK Cell Receptors. Immunity. 2017;46:1018-1029.e7 pubmed publisher
  5. Kasturi S, Kozlowski P, Nakaya H, Burger M, Russo P, Pham M, et al. Adjuvanting a Simian Immunodeficiency Virus Vaccine with Toll-Like Receptor Ligands Encapsulated in Nanoparticles Induces Persistent Antibody Responses and Enhanced Protection in TRIM5α Restrictive Macaques. J Virol. 2017;91: pubmed publisher
  6. Zhu H, Hu F, Sun X, Zhang X, Zhu L, Liu X, et al. CD16+ Monocyte Subset Was Enriched and Functionally Exacerbated in Driving T-Cell Activation and B-Cell Response in Systemic Lupus Erythematosus. Front Immunol. 2016;7:512 pubmed
  7. Senbabaoglu Y, Gejman R, Winer A, Liu M, Van Allen E, de Velasco G, et al. Tumor immune microenvironment characterization in clear cell renal cell carcinoma identifies prognostic and immunotherapeutically relevant messenger RNA signatures. Genome Biol. 2016;17:231 pubmed
  8. Geng S, Chen K, Yuan R, Peng L, Maitra U, Diao N, et al. The persistence of low-grade inflammatory monocytes contributes to aggravated atherosclerosis. Nat Commun. 2016;7:13436 pubmed publisher
  9. Demers K, Makedonas G, Buggert M, Eller M, Ratcliffe S, Goonetilleke N, et al. Temporal Dynamics of CD8+ T Cell Effector Responses during Primary HIV Infection. PLoS Pathog. 2016;12:e1005805 pubmed publisher
  10. Williams D, Engle E, Shirk E, Queen S, Gama L, Mankowski J, et al. Splenic Damage during SIV Infection: Role of T-Cell Depletion and Macrophage Polarization and Infection. Am J Pathol. 2016;186:2068-2087 pubmed publisher
  11. Parameswaran R, Ramakrishnan P, Moreton S, Xia Z, Hou Y, Lee D, et al. Repression of GSK3 restores NK cell cytotoxicity in AML patients. Nat Commun. 2016;7:11154 pubmed publisher
  12. Ludigs K, Jandus C, Utzschneider D, Staehli F, Bessoles S, Dang A, et al. NLRC5 shields T lymphocytes from NK-cell-mediated elimination under inflammatory conditions. Nat Commun. 2016;7:10554 pubmed publisher
  13. Westman J, Papareddy P, Dahlgren M, Chakrakodi B, Norrby Teglund A, Smeds E, et al. Extracellular Histones Induce Chemokine Production in Whole Blood Ex Vivo and Leukocyte Recruitment In Vivo. PLoS Pathog. 2015;11:e1005319 pubmed publisher
  14. Venkatasubramanian S, Tripathi D, Tucker T, Paidipally P, Cheekatla S, Welch E, et al. Tissue factor expression by myeloid cells contributes to protective immune response against Mycobacterium tuberculosis infection. Eur J Immunol. 2016;46:464-79 pubmed publisher
  15. Schulz A, Mälzer J, Domingo C, Jürchott K, Grützkau A, Babel N, et al. Low Thymic Activity and Dendritic Cell Numbers Are Associated with the Immune Response to Primary Viral Infection in Elderly Humans. J Immunol. 2015;195:4699-711 pubmed publisher
  16. WILLIAMS K, KILLEBREW D, Clary G, Seawell J, Meeker R. Differential regulation of macrophage phenotype by mature and pro-nerve growth factor. J Neuroimmunol. 2015;285:76-93 pubmed publisher
  17. Amos J, Himes J, Armand L, Gurley T, Martinez D, Colvin L, et al. Rapid Development of gp120-Focused Neutralizing B Cell Responses during Acute Simian Immunodeficiency Virus Infection of African Green Monkeys. J Virol. 2015;89:9485-98 pubmed publisher
  18. Mende N, Kuchen E, Lesche M, Grinenko T, Kokkaliaris K, Hanenberg H, et al. CCND1-CDK4-mediated cell cycle progression provides a competitive advantage for human hematopoietic stem cells in vivo. J Exp Med. 2015;212:1171-83 pubmed publisher
  19. O Brien E, Abdulahad W, Rutgers A, Huitema M, O Reilly V, Coughlan A, et al. Intermediate monocytes in ANCA vasculitis: increased surface expression of ANCA autoantigens and IL-1β secretion in response to anti-MPO antibodies. Sci Rep. 2015;5:11888 pubmed publisher
  20. Chalan P, Bijzet J, Huitema M, Kroesen B, Brouwer E, Boots A. Expression of Lectin-Like Transcript 1, the Ligand for CD161, in Rheumatoid Arthritis. PLoS ONE. 2015;10:e0132436 pubmed publisher
  21. Chowdhury A, Hayes T, Bosinger S, Lawson B, Vanderford T, Schmitz J, et al. Differential Impact of In Vivo CD8+ T Lymphocyte Depletion in Controller versus Progressor Simian Immunodeficiency Virus-Infected Macaques. J Virol. 2015;89:8677-86 pubmed publisher
  22. Weldon A, Moldovan I, Cabling M, Hernandez E, Hsu S, Gonzalez J, et al. Surface APRIL Is Elevated on Myeloid Cells and Is Associated with Disease Activity in Patients with Rheumatoid Arthritis. J Rheumatol. 2015;42:749-59 pubmed publisher
  23. Chauhan A, Chen C, Moore T, DiPaolo R. Induced expression of FcγRIIIa (CD16a) on CD4+ T cells triggers generation of IFN-γhigh subset. J Biol Chem. 2015;290:5127-40 pubmed publisher
  24. Hünniger K, Bieber K, Martin R, Lehnert T, Figge M, Löffler J, et al. A second stimulus required for enhanced antifungal activity of human neutrophils in blood is provided by anaphylatoxin C5a. J Immunol. 2015;194:1199-210 pubmed publisher
  25. Hartung E, Becker M, Bachem A, Reeg N, Jäkel A, Hutloff A, et al. Induction of potent CD8 T cell cytotoxicity by specific targeting of antigen to cross-presenting dendritic cells in vivo via murine or human XCR1. J Immunol. 2015;194:1069-79 pubmed publisher
  26. Presnell S, Al Attar A, Cichocki F, Miller J, Lutz C. Human natural killer cell microRNA: differential expression of MIR181A1B1 and MIR181A2B2 genes encoding identical mature microRNAs. Genes Immun. 2015;16:89-98 pubmed publisher
  27. Mandl M, Schmitz S, Weber C, Hristov M. Characterization of the CD14++CD16+ monocyte population in human bone marrow. PLoS ONE. 2014;9:e112140 pubmed publisher
  28. Mohanty S, Joshi S, Ueda I, Wilson J, Blevins T, Siconolfi B, et al. Prolonged proinflammatory cytokine production in monocytes modulated by interleukin 10 after influenza vaccination in older adults. J Infect Dis. 2015;211:1174-84 pubmed publisher
  29. Holder G, McGary C, Johnson E, Zheng R, John V, Sugimoto C, et al. Expression of the mannose receptor CD206 in HIV and SIV encephalitis: a phenotypic switch of brain perivascular macrophages with virus infection. J Neuroimmune Pharmacol. 2014;9:716-26 pubmed publisher
  30. Jiang B, Wu X, Li X, Yang X, Zhou Y, Yan H, et al. Expansion of NK cells by engineered K562 cells co-expressing 4-1BBL and mMICA, combined with soluble IL-21. Cell Immunol. 2014;290:10-20 pubmed publisher
  31. Jitschin R, Braun M, Büttner M, Dettmer Wilde K, Bricks J, Berger J, et al. CLL-cells induce IDOhi CD14+HLA-DRlo myeloid-derived suppressor cells that inhibit T-cell responses and promote TRegs. Blood. 2014;124:750-60 pubmed publisher
  32. Wilson E, Singh A, Hullsiek K, Gibson D, Henry W, Lichtenstein K, et al. Monocyte-activation phenotypes are associated with biomarkers of inflammation and coagulation in chronic HIV infection. J Infect Dis. 2014;210:1396-406 pubmed publisher
  33. Sereti I, Estes J, Thompson W, Morcock D, Fischl M, Croughs T, et al. Decreases in colonic and systemic inflammation in chronic HIV infection after IL-7 administration. PLoS Pathog. 2014;10:e1003890 pubmed publisher
  34. Babu R, Brown A. A consensus surface activation marker signature is partially dependent on human immunodeficiency virus type 1 Nef expression within productively infected macrophages. Retrovirology. 2013;10:155 pubmed publisher
  35. Chicoine L, Rodino Klapac L, Shao G, Xu R, Bremer W, Camboni M, et al. Vascular delivery of rAAVrh74.MCK.GALGT2 to the gastrocnemius muscle of the rhesus macaque stimulates the expression of dystrophin and laminin ?2 surrogates. Mol Ther. 2014;22:713-24 pubmed publisher
  36. Wiernik A, Foley B, Zhang B, Verneris M, Warlick E, Gleason M, et al. Targeting natural killer cells to acute myeloid leukemia in vitro with a CD16 x 33 bispecific killer cell engager and ADAM17 inhibition. Clin Cancer Res. 2013;19:3844-55 pubmed publisher
  37. Fung E, Esposito L, Todd J, Wicker L. Multiplexed immunophenotyping of human antigen-presenting cells in whole blood by polychromatic flow cytometry. Nat Protoc. 2010;5:357-70 pubmed publisher