This is a Validated Antibody Database (VAD) review about chimpanzee LOC457259, based on 14 published articles (read how Labome selects the articles), using LOC457259 antibody in all methods. It is aimed to help Labome visitors find the most suited LOC457259 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
LOC457259 synonym: FCGR1A; high affinity immunoglobulin gamma Fc receptor I; Fc fragment of IgG, high affinity Ia, receptor (CD64)

BioLegend
mouse monoclonal (10.1)
  • mass cytometry; human; loading ...; fig 2j
BioLegend LOC457259 antibody (Biolegend, 305002) was used in mass cytometry on human samples (fig 2j). Cell (2019) ncbi
mouse monoclonal (10.1)
  • flow cytometry; human; 1:200; loading ...; fig 1c
BioLegend LOC457259 antibody (Biolegend, 10.1) was used in flow cytometry on human samples at 1:200 (fig 1c). Front Immunol (2018) ncbi
mouse monoclonal (10.1)
  • flow cytometry; human; fig 4a
BioLegend LOC457259 antibody (BioLegend, 305022) was used in flow cytometry on human samples (fig 4a). J Exp Med (2018) ncbi
mouse monoclonal (10.1)
  • flow cytometry; human; loading ...; fig 1a
BioLegend LOC457259 antibody (Biolegend, 305002) was used in flow cytometry on human samples (fig 1a). Cell (2018) ncbi
mouse monoclonal (10.1)
  • flow cytometry; human; loading ...; fig 1e
BioLegend LOC457259 antibody (BioLegend, 10.1) was used in flow cytometry on human samples (fig 1e). J Exp Med (2018) ncbi
mouse monoclonal (10.1)
  • flow cytometry; human; loading ...; fig 4a
BioLegend LOC457259 antibody (BioLegend, 10.1) was used in flow cytometry on human samples (fig 4a). Thromb Res (2017) ncbi
mouse monoclonal (10.1)
  • flow cytometry; human; 1:50; loading ...; fig s2a
In order to define the transcriptional network specifies conferring microglia identity, BioLegend LOC457259 antibody (BioLegend, 305014) was used in flow cytometry on human samples at 1:50 (fig s2a). Science (2017) ncbi
mouse monoclonal (10.1)
  • flow cytometry; human; loading ...; fig st1
In order to investigate the effect of PD-1 expression on phagocytosis and tumour immunity, BioLegend LOC457259 antibody (Biolegend, 10.1) was used in flow cytometry on human samples (fig st1). Nature (2017) ncbi
mouse monoclonal (10.1)
  • flow cytometry; human; loading ...; fig s1c
In order to determine the localization of FcgammaRI, FcgammaRII, and SIRPalpha in macrophages, BioLegend LOC457259 antibody (BioLegend, 10.1) was used in flow cytometry on human samples (fig s1c). J Cell Biol (2017) ncbi
mouse monoclonal (10.1)
  • blocking or activating experiments; human; loading ...; fig 3a
  • flow cytometry; human; loading ...; fig 3
In order to determine the contribution of CD16 positive monocytes to antibody-dependent cellular cytotoxicity, BioLegend LOC457259 antibody (BioLegend, 10.1) was used in blocking or activating experiments on human samples (fig 3a) and in flow cytometry on human samples (fig 3). Sci Rep (2016) ncbi
mouse monoclonal (10.1)
  • flow cytometry; human; loading ...; fig s6a
BioLegend LOC457259 antibody (Biolegend, 305019) was used in flow cytometry on human samples (fig s6a). Sci Rep (2016) ncbi
mouse monoclonal (10.1)
  • flow cytometry; human
In order to test if macrophages contribute to the effect of daratumumab treatment, BioLegend LOC457259 antibody (Biolegend, 305006) was used in flow cytometry on human samples . MAbs (2015) ncbi
mouse monoclonal (10.1)
  • flow cytometry; human
BioLegend LOC457259 antibody (BioLegend, 10.1) was used in flow cytometry on human samples . PLoS ONE (2014) ncbi
mouse monoclonal (10.1)
  • flow cytometry; human
BioLegend LOC457259 antibody (Biolegend, 10.1) was used in flow cytometry on human samples . Immunology (2014) ncbi
Articles Reviewed
  1. Wagner J, Rapsomaniki M, Chevrier S, Anzeneder T, Langwieder C, Dykgers A, et al. A Single-Cell Atlas of the Tumor and Immune Ecosystem of Human Breast Cancer. Cell. 2019;177:1330-1345.e18 pubmed publisher
  2. Jones G, Bain C, Fenton T, Kelly A, Brown S, Ivens A, et al. Dynamics of Colon Monocyte and Macrophage Activation During Colitis. Front Immunol. 2018;9:2764 pubmed publisher
  3. Kelly A, Günaltay S, McEntee C, Shuttleworth E, Smedley C, Houston S, et al. Human monocytes and macrophages regulate immune tolerance via integrin αvβ8-mediated TGFβ activation. J Exp Med. 2018;215:2725-2736 pubmed publisher
  4. Olin A, Henckel E, Chen Y, Lakshmikanth T, Pou C, Mikes J, et al. Stereotypic Immune System Development in Newborn Children. Cell. 2018;174:1277-1292.e14 pubmed publisher
  5. Bujko A, Atlasy N, Landsverk O, Richter L, Yaqub S, Horneland R, et al. Transcriptional and functional profiling defines human small intestinal macrophage subsets. J Exp Med. 2018;215:441-458 pubmed publisher
  6. Hally K, La Flamme A, Larsen P, Harding S. Platelet Toll-like receptor (TLR) expression and TLR-mediated platelet activation in acute myocardial infarction. Thromb Res. 2017;158:8-15 pubmed publisher
  7. Gosselin D, Skola D, Coufal N, Holtman I, Schlachetzki J, Sajti E, et al. An environment-dependent transcriptional network specifies human microglia identity. Science. 2017;356: pubmed publisher
  8. Gordon S, Maute R, Dulken B, Hutter G, George B, McCracken M, et al. PD-1 expression by tumour-associated macrophages inhibits phagocytosis and tumour immunity. Nature. 2017;545:495-499 pubmed publisher
  9. Lopes F, Bálint Å, Valvo S, Felce J, Hessel E, Dustin M, et al. Membrane nanoclusters of FcγRI segregate from inhibitory SIRPα upon activation of human macrophages. J Cell Biol. 2017;216:1123-1141 pubmed publisher
  10. Yeap W, Wong K, Shimasaki N, Teo E, Quek J, Yong H, et al. CD16 is indispensable for antibody-dependent cellular cytotoxicity by human monocytes. Sci Rep. 2016;6:34310 pubmed publisher
  11. Huynh L, Kusnadi A, Park S, Murata K, Park Min K, Ivashkiv L. Opposing regulation of the late phase TNF response by mTORC1-IL-10 signaling and hypoxia in human macrophages. Sci Rep. 2016;6:31959 pubmed publisher
  12. Overdijk M, Verploegen S, Bögels M, van Egmond M, Lammerts van Bueren J, Mutis T, et al. Antibody-mediated phagocytosis contributes to the anti-tumor activity of the therapeutic antibody daratumumab in lymphoma and multiple myeloma. MAbs. 2015;7:311-21 pubmed publisher
  13. Al Barwani F, Young S, Baird M, Larsen D, Ward V. Mannosylation of virus-like particles enhances internalization by antigen presenting cells. PLoS ONE. 2014;9:e104523 pubmed publisher
  14. Vogel K, Thomann S, Vogel B, Schuster P, Schmidt B. Both plasmacytoid dendritic cells and monocytes stimulate natural killer cells early during human herpes simplex virus type 1 infections. Immunology. 2014;143:588-600 pubmed publisher