This is a Validated Antibody Database (VAD) review about chimpanzee ITGA4, based on 10 published articles (read how Labome selects the articles), using ITGA4 antibody in all methods. It is aimed to help Labome visitors find the most suited ITGA4 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
ITGA4 synonym: integrin alpha-4; integrin alpha 4; integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)

BioLegend
mouse monoclonal (9F10)
  • flow cytometry; human; loading ...; fig 1a
BioLegend ITGA4 antibody (Biolegend, 304302) was used in flow cytometry on human samples (fig 1a). Cell (2018) ncbi
mouse monoclonal (9F10)
  • flow cytometry; human
In order to characterize activated T cells in joint tissue from patients with rheumatoid arthritis, BioLegend ITGA4 antibody (biolegend, 9F10) was used in flow cytometry on human samples . Nature (2017) ncbi
mouse monoclonal (9F10)
  • flow cytometry; human; loading ...; fig 2b
BioLegend ITGA4 antibody (BioLegend, 9F10) was used in flow cytometry on human samples (fig 2b). Stem Cells Dev (2017) ncbi
mouse monoclonal (9F10)
  • flow cytometry; Rhesus monkey; 1 ug/ml; loading ...
In order to examine the kinetics of SIV-specific CD8+ T cell cytolytic factor expression in peripheral blood, lymph node, spleen, and gut mucosa from early acute infection through chronic infection, BioLegend ITGA4 antibody (Biolegend, 9F10) was used in flow cytometry on Rhesus monkey samples at 1 ug/ml. PLoS Pathog (2016) ncbi
mouse monoclonal (9F10)
  • flow cytometry; human; 1:800; loading ...; fig 2d
In order to report disease-related phenotypes in human pluripotent stem cells that capture familial dysautonomia severity, BioLegend ITGA4 antibody (BioLegend, 304314) was used in flow cytometry on human samples at 1:800 (fig 2d). Nat Med (2016) ncbi
mouse monoclonal (9F10)
  • flow cytometry; human; fig 4
In order to determine modulation of presentation of cell surfaced calreticulin by alpha-integrin function and expression, BioLegend ITGA4 antibody (Biolegend, 9F10) was used in flow cytometry on human samples (fig 4). Cell Death Dis (2016) ncbi
mouse monoclonal (9F10)
  • flow cytometry; human; 1:800; fig 1
BioLegend ITGA4 antibody (BioLegend, 304314) was used in flow cytometry on human samples at 1:800 (fig 1). Nature (2016) ncbi
mouse monoclonal (9F10)
  • flow cytometry; human; fig 5
In order to study dual involvement of S1P1 and S1P2 receptors in regulation of human cerebro-microvascular endothelial baso-lateral adhesion and barrier function by S1P, BioLegend ITGA4 antibody (BioLegend, 304308) was used in flow cytometry on human samples (fig 5). Sci Rep (2016) ncbi
mouse monoclonal (9F10)
  • flow cytometry; human; fig 4
In order to determine the differential regulation of the inflammatory phenotype of brain microvascular endothelial cells by pro-inflammatory TNFalpha and IL-1beta, BioLegend ITGA4 antibody (Biolegend, 304308) was used in flow cytometry on human samples (fig 4). J Neuroinflammation (2015) ncbi
mouse monoclonal (9F10)
  • flow cytometry; human; fig 7
In order to characterize VLA-4 blockade and promotion of differential routes into human CNS involving MCAM-adhesion of TH17 cells and PSGL-1 rolling of T cells, BioLegend ITGA4 antibody (BioLegend, 9F10) was used in flow cytometry on human samples (fig 7). J Exp Med (2014) ncbi
Articles Reviewed
  1. Olin A, Henckel E, Chen Y, Lakshmikanth T, Pou C, Mikes J, et al. Stereotypic Immune System Development in Newborn Children. Cell. 2018;174:1277-1292.e14 pubmed publisher
  2. Rao D, Gurish M, Marshall J, Slowikowski K, Fonseka C, Liu Y, et al. Pathologically expanded peripheral T helper cell subset drives B cells in rheumatoid arthritis. Nature. 2017;542:110-114 pubmed publisher
  3. Chorzalska A, Kim J, Roder K, Tepper A, Ahsan N, Rao R, et al. Long-Term Exposure to Imatinib Mesylate Downregulates Hippo Pathway and Activates YAP in a Model of Chronic Myelogenous Leukemia. Stem Cells Dev. 2017;26:656-677 pubmed publisher
  4. Roberts E, Carnathan D, Li H, Shaw G, Silvestri G, Betts M. Collapse of Cytolytic Potential in SIV-Specific CD8+ T Cells Following Acute SIV Infection in Rhesus Macaques. PLoS Pathog. 2016;12:e1006135 pubmed publisher
  5. Zeltner N, Fattahi F, Dubois N, Saurat N, Lafaille F, Shang L, et al. Capturing the biology of disease severity in a PSC-based model of familial dysautonomia. Nat Med. 2016;22:1421-1427 pubmed publisher
  6. Liu C, LeClair P, Monajemi M, Sly L, Reid G, Lim C. α-Integrin expression and function modulates presentation of cell surface calreticulin. Cell Death Dis. 2016;7:e2268 pubmed publisher
  7. Fattahi F, Steinbeck J, Kriks S, Tchieu J, Zimmer B, Kishinevsky S, et al. Deriving human ENS lineages for cell therapy and drug discovery in Hirschsprung disease. Nature. 2016;531:105-9 pubmed publisher
  8. Wiltshire R, Nelson V, Kho D, Angel C, O Carroll S, Graham E. Regulation of human cerebro-microvascular endothelial baso-lateral adhesion and barrier function by S1P through dual involvement of S1P1 and S1P2 receptors. Sci Rep. 2016;6:19814 pubmed publisher
  9. O Carroll S, Kho D, Wiltshire R, Nelson V, Rotimi O, Johnson R, et al. Pro-inflammatory TNFα and IL-1β differentially regulate the inflammatory phenotype of brain microvascular endothelial cells. J Neuroinflammation. 2015;12:131 pubmed publisher
  10. Schneider Hohendorf T, Rossaint J, Mohan H, Böning D, Breuer J, Kuhlmann T, et al. VLA-4 blockade promotes differential routes into human CNS involving PSGL-1 rolling of T cells and MCAM-adhesion of TH17 cells. J Exp Med. 2014;211:1833-46 pubmed publisher