This is a Validated Antibody Database (VAD) review about chicken TGFB1I1, based on 75 published articles (read how Labome selects the articles), using TGFB1I1 antibody in all methods. It is aimed to help Labome visitors find the most suited TGFB1I1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
TGFB1I1 synonym: PXN

BD Biosciences
mouse monoclonal (349/Paxillin)
  • immunocytochemistry; human; 1:100; loading ...; fig 5d
BD Biosciences TGFB1I1 antibody (BD Biosciences, 610051) was used in immunocytochemistry on human samples at 1:100 (fig 5d). Cell Mol Life Sci (2022) ncbi
mouse monoclonal (349/Paxillin)
  • immunocytochemistry; human; loading ...; fig s2j
BD Biosciences TGFB1I1 antibody (BD Biosciences, 610052) was used in immunocytochemistry on human samples (fig s2j). Cell Rep (2022) ncbi
mouse monoclonal (349/Paxillin)
  • immunohistochemistry - paraffin section; mouse; loading ...; fig 2a
  • immunocytochemistry; mouse; fig 1c
  • western blot; mouse; fig 1a
BD Biosciences TGFB1I1 antibody (BD Biosciences, 610051) was used in immunohistochemistry - paraffin section on mouse samples (fig 2a), in immunocytochemistry on mouse samples (fig 1c) and in western blot on mouse samples (fig 1a). Cancers (Basel) (2021) ncbi
mouse monoclonal (349/Paxillin)
  • immunocytochemistry; human; 1:200; loading ...; fig 4i
BD Biosciences TGFB1I1 antibody (BD Biosciences, 612405) was used in immunocytochemistry on human samples at 1:200 (fig 4i). Cell Rep (2021) ncbi
mouse monoclonal (349/Paxillin)
  • immunocytochemistry; human; 1:500; loading ...; fig s2a
  • western blot; human; 1:1000; loading ...; fig 3a, 4d
BD Biosciences TGFB1I1 antibody (BD, 612405) was used in immunocytochemistry on human samples at 1:500 (fig s2a) and in western blot on human samples at 1:1000 (fig 3a, 4d). Sci Rep (2021) ncbi
mouse monoclonal (165/Paxillin)
  • immunocytochemistry; human; loading ...; fig s2a
BD Biosciences TGFB1I1 antibody (Transduction laboratories, 165) was used in immunocytochemistry on human samples (fig s2a). Angiogenesis (2021) ncbi
mouse monoclonal (177/Paxillin)
  • immunocytochemistry; human; 1:500; loading ...; fig 3a
BD Biosciences TGFB1I1 antibody (BD, 177) was used in immunocytochemistry on human samples at 1:500 (fig 3a). Sci Adv (2021) ncbi
mouse monoclonal (349/Paxillin)
  • immunocytochemistry; human; 1:300; loading ...; fig 4s1
BD Biosciences TGFB1I1 antibody (BD Biosciences, 610051) was used in immunocytochemistry on human samples at 1:300 (fig 4s1). elife (2020) ncbi
mouse monoclonal (349/Paxillin)
  • immunocytochemistry; human; loading ...; fig 1a
BD Biosciences TGFB1I1 antibody (BD Biosciences, 610051) was used in immunocytochemistry on human samples (fig 1a). Mol Biol Cell (2020) ncbi
mouse monoclonal (349/Paxillin)
  • immunocytochemistry; mouse; loading ...; fig s5e
BD Biosciences TGFB1I1 antibody (BD Bioscience, 610051) was used in immunocytochemistry on mouse samples (fig s5e). Science (2020) ncbi
mouse monoclonal (349/Paxillin)
  • immunohistochemistry; human; loading ...; fig 4e
BD Biosciences TGFB1I1 antibody (BD Biosciences, 612405) was used in immunohistochemistry on human samples (fig 4e). J Exp Clin Cancer Res (2019) ncbi
mouse monoclonal (349/Paxillin)
  • immunocytochemistry; human; loading ...; fig s7g
BD Biosciences TGFB1I1 antibody (BD Transduction, 610051) was used in immunocytochemistry on human samples (fig s7g). Cell (2019) ncbi
mouse monoclonal (349/Paxillin)
  • immunocytochemistry; human; loading ...; fig 1c
BD Biosciences TGFB1I1 antibody (BD, 610052) was used in immunocytochemistry on human samples (fig 1c). BMC Cancer (2019) ncbi
mouse monoclonal (349/Paxillin)
  • immunocytochemistry; human; 1:100; loading ...; fig 4a
BD Biosciences TGFB1I1 antibody (BD, 610052) was used in immunocytochemistry on human samples at 1:100 (fig 4a). Mol Biol Cell (2019) ncbi
mouse monoclonal (177/Paxillin)
  • immunocytochemistry; human; 1:100; loading ...; fig 1e
BD Biosciences TGFB1I1 antibody (BD Biosciences, 610569) was used in immunocytochemistry on human samples at 1:100 (fig 1e). J Cell Sci (2019) ncbi
mouse monoclonal (349/Paxillin)
  • western blot; mouse; loading ...; fig s3d
BD Biosciences TGFB1I1 antibody (BD Biosciences, 612405) was used in western blot on mouse samples (fig s3d). Immunity (2019) ncbi
mouse monoclonal (349/Paxillin)
  • immunocytochemistry; mouse; loading ...; fig s5b
BD Biosciences TGFB1I1 antibody (BD Transduction, 610051) was used in immunocytochemistry on mouse samples (fig s5b). Dev Cell (2018) ncbi
mouse monoclonal (165/Paxillin)
  • western blot; mouse; 1:1000; loading ...; fig 4b
BD Biosciences TGFB1I1 antibody (BD, 165) was used in western blot on mouse samples at 1:1000 (fig 4b). Cell Stem Cell (2018) ncbi
mouse monoclonal (349/Paxillin)
  • immunocytochemistry; human; fig 5c
BD Biosciences TGFB1I1 antibody (BD Biosciences, 610051) was used in immunocytochemistry on human samples (fig 5c). Neuron (2018) ncbi
mouse monoclonal (349/Paxillin)
  • western blot; human; 1:1000; fig 2a
BD Biosciences TGFB1I1 antibody (BD Transduction Laboratories, 610051) was used in western blot on human samples at 1:1000 (fig 2a). Nature (2018) ncbi
mouse monoclonal (165/Paxillin)
  • immunocytochemistry; human; loading ...; fig 4a
BD Biosciences TGFB1I1 antibody (BD, 610619) was used in immunocytochemistry on human samples (fig 4a). J Clin Invest (2017) ncbi
mouse monoclonal (349/Paxillin)
  • western blot; hamsters; loading ...; fig 1e
BD Biosciences TGFB1I1 antibody (BD, 610052) was used in western blot on hamsters samples (fig 1e). J Cell Sci (2017) ncbi
mouse monoclonal (349/Paxillin)
  • western blot; human; 1:1000; fig 3b
In order to elucidate the mechanism by which 15d-PGJ2 suppresses human thyroid carcinoma cell migration, BD Biosciences TGFB1I1 antibody (BD Biosciences, 610051) was used in western blot on human samples at 1:1000 (fig 3b). Oncol Lett (2017) ncbi
mouse monoclonal (165/Paxillin)
  • immunohistochemistry; human; loading ...; fig 8d
  • western blot; human; loading ...; fig s8a
In order to study factors that allow tumor cells to metastasize, BD Biosciences TGFB1I1 antibody (BD, 610620) was used in immunohistochemistry on human samples (fig 8d) and in western blot on human samples (fig s8a). Mol Biol Cell (2017) ncbi
mouse monoclonal (349/Paxillin)
  • immunocytochemistry; human; 1:100; loading ...; fig 2e
BD Biosciences TGFB1I1 antibody (BD Biosciences, 610051) was used in immunocytochemistry on human samples at 1:100 (fig 2e). Proc Natl Acad Sci U S A (2017) ncbi
mouse monoclonal (177/Paxillin)
  • western blot; dogs; loading ...; fig 4c
In order to demonstrate that non-muscle myosin II plays a critical role in airway smooth muscle contraction, BD Biosciences TGFB1I1 antibody (BD Transduction, 610569) was used in western blot on dogs samples (fig 4c). J Physiol (2017) ncbi
mouse monoclonal (165/Paxillin)
  • immunocytochemistry; human; 1:200; loading ...; fig 4
In order to report that cool-associated tyrosine phosphorylated protein-1 is required for anchorage-independent growth of cervical carcinoma cells, BD Biosciences TGFB1I1 antibody (BD, 610620) was used in immunocytochemistry on human samples at 1:200 (fig 4). J Biol Chem (2017) ncbi
mouse monoclonal (349/Paxillin)
  • immunocytochemistry; mouse; 1:300; loading ...; fig 4b
In order to find that mice with a dysfunctional fibronectin-synergy motif suffer from surprisingly mild platelet adhesion and bleeding defects due to delayed thrombus formation after vessel injury, BD Biosciences TGFB1I1 antibody (PharMingen, 610051) was used in immunocytochemistry on mouse samples at 1:300 (fig 4b). elife (2017) ncbi
mouse monoclonal (165/Paxillin)
  • immunocytochemistry; human; 1:50; fig 3c
BD Biosciences TGFB1I1 antibody (BD Biosciences, 610620) was used in immunocytochemistry on human samples at 1:50 (fig 3c). Mol Med Rep (2016) ncbi
mouse monoclonal (349/Paxillin)
  • immunocytochemistry; human; fig s12
In order to develop a new multiplex dSTORM imaging strategy to localize epitopes on activated T-cells, BD Biosciences TGFB1I1 antibody (BD Biosciences, 610052) was used in immunocytochemistry on human samples (fig s12). Mol Biol Cell (2016) ncbi
mouse monoclonal (349/Paxillin)
  • immunocytochemistry; human; loading ...; fig 3a
BD Biosciences TGFB1I1 antibody (BD Biosciences, 349) was used in immunocytochemistry on human samples (fig 3a). Oncogene (2017) ncbi
mouse monoclonal (165/Paxillin)
  • immunocytochemistry; hamsters; loading ...; fig 6c
In order to elucidate pH-dependent NHE1 activity, BD Biosciences TGFB1I1 antibody (BD Transduction Laboratories, 610620) was used in immunocytochemistry on hamsters samples (fig 6c). J Biol Chem (2016) ncbi
mouse monoclonal (349/Paxillin)
  • immunocytochemistry; human; fig 3
  • western blot; human; fig 7
In order to investigate the effects of TNF treatment and SFK activation using human dermal microvascular endothelial cells, BD Biosciences TGFB1I1 antibody (BD Biosciences, 612405) was used in immunocytochemistry on human samples (fig 3) and in western blot on human samples (fig 7). PLoS ONE (2016) ncbi
mouse monoclonal (165/Paxillin)
  • immunocytochemistry; human; fig 5
BD Biosciences TGFB1I1 antibody (BD biosciences, 610620) was used in immunocytochemistry on human samples (fig 5). Cancer Cell Int (2016) ncbi
mouse monoclonal (349/Paxillin)
  • immunocytochemistry; human
In order to find genes involved in tumor cell migration, BD Biosciences TGFB1I1 antibody (BD Biosciences, 610052) was used in immunocytochemistry on human samples . Sci Rep (2016) ncbi
mouse monoclonal (349/Paxillin)
  • western blot; mouse; 1:1000; loading ...; fig 4a
In order to report that oncogenic transformation results in microvesicles, BD Biosciences TGFB1I1 antibody (BD Biosciences, 612405) was used in western blot on mouse samples at 1:1000 (fig 4a). J Biol Chem (2016) ncbi
mouse monoclonal (349/Paxillin)
  • immunocytochemistry; human; loading ...; fig 1d
  • immunocytochemistry; dogs; loading ...; fig 3e
In order to find that mitotic focal adhesions link mitotic cell shape and spindle orientation, BD Biosciences TGFB1I1 antibody (BD Biosciences, 810051) was used in immunocytochemistry on human samples (fig 1d) and in immunocytochemistry on dogs samples (fig 3e). Sci Rep (2016) ncbi
mouse monoclonal (165/Paxillin)
  • immunocytochemistry; mouse; 1:250; fig 4c
In order to explore how the interaction between beta1-integrin and Fgf2 contributes to the satellite cell niche, BD Biosciences TGFB1I1 antibody (BD Biosciences, 610619) was used in immunocytochemistry on mouse samples at 1:250 (fig 4c). Nat Med (2016) ncbi
mouse monoclonal (349/Paxillin)
  • western blot; mouse; loading ...; fig 7a
BD Biosciences TGFB1I1 antibody (BD, 610051) was used in western blot on mouse samples (fig 7a). J Exp Med (2016) ncbi
mouse monoclonal (349/Paxillin)
  • immunocytochemistry; mouse; 1:200; fig 5
  • western blot; mouse; 1:1000; fig 4
  • western blot; rat; 1:1000; fig s3
In order to determine regulation of metastasis and cell invasion through the phosphorylation of paxillin due to cytoplasmic cyclin D1, BD Biosciences TGFB1I1 antibody (BD Biosciences, 610051) was used in immunocytochemistry on mouse samples at 1:200 (fig 5), in western blot on mouse samples at 1:1000 (fig 4) and in western blot on rat samples at 1:1000 (fig s3). Nat Commun (2016) ncbi
mouse monoclonal (349/Paxillin)
  • western blot; mouse; fig 1
BD Biosciences TGFB1I1 antibody (bD Bioscience, 610051) was used in western blot on mouse samples (fig 1). Cell Signal (2016) ncbi
mouse monoclonal (349/Paxillin)
  • western blot; human; fig 4
In order to study inhibition of Rac1 trafficking to the cell border by RhoB control of the endothelial barrier recovery, BD Biosciences TGFB1I1 antibody (BD, 610051) was used in western blot on human samples (fig 4). J Cell Biol (2016) ncbi
mouse monoclonal (349/Paxillin)
  • immunohistochemistry; mouse; 1:200; loading ...; fig 2c
  • western blot; mouse; 1:1000; loading ...; fig s1e
In order to investigate how recycled integrins assemble into new adhesions, BD Biosciences TGFB1I1 antibody (BD Biosciences, 349) was used in immunohistochemistry on mouse samples at 1:200 (fig 2c) and in western blot on mouse samples at 1:1000 (fig s1e). Nat Cell Biol (2016) ncbi
mouse monoclonal (349/Paxillin)
  • immunocytochemistry; mouse; fig 5
  • western blot; mouse; fig 5
In order to learn about the control of differentiation in mammary epithelial cells by the integrin-mediated ILK-parvin-alpha-Pix signaling axis, BD Biosciences TGFB1I1 antibody (BD Transduction, 610052) was used in immunocytochemistry on mouse samples (fig 5) and in western blot on mouse samples (fig 5). J Cell Physiol (2016) ncbi
mouse monoclonal (349/Paxillin)
  • immunocytochemistry; zebrafish ; 1:100; fig 1
  • western blot; zebrafish ; 1:1000; fig s2
BD Biosciences TGFB1I1 antibody (BD Transduction Laboratories, 610051) was used in immunocytochemistry on zebrafish samples at 1:100 (fig 1) and in western blot on zebrafish samples at 1:1000 (fig s2). PLoS ONE (2016) ncbi
mouse monoclonal (177/Paxillin)
  • immunocytochemistry; human; 1:1000; fig 8
In order to elucidate how spindle orientation occurs through a ligand-independent intgrin beta 1 mechanosensory complex, BD Biosciences TGFB1I1 antibody (BD Biosciences, 610569) was used in immunocytochemistry on human samples at 1:1000 (fig 8). Nat Commun (2016) ncbi
mouse monoclonal (165/Paxillin)
  • immunocytochemistry; human; 1:200; fig s1
BD Biosciences TGFB1I1 antibody (BD Biosciences, 610619) was used in immunocytochemistry on human samples at 1:200 (fig s1). J Cell Biol (2016) ncbi
mouse monoclonal (349/Paxillin)
  • western blot; human; 1:1000; fig s5
BD Biosciences TGFB1I1 antibody (BD Biosciences, 610051) was used in western blot on human samples at 1:1000 (fig s5). J Cell Biol (2016) ncbi
mouse monoclonal (349/Paxillin)
  • immunocytochemistry; human; 1:400; fig 6
  • western blot; human; 1:1000; fig 5
In order to determine how modulation of FAK and Src adhesion signalling occurs without the need for adhesion complex composition, BD Biosciences TGFB1I1 antibody (BD Biosciences, 610051) was used in immunocytochemistry on human samples at 1:400 (fig 6) and in western blot on human samples at 1:1000 (fig 5). J Cell Biol (2016) ncbi
mouse monoclonal (349/Paxillin)
  • immunocytochemistry; mouse; 1:400; fig 1
  • western blot; mouse; 1:1000; fig 4
In order to determine the role of Kindlin-2 tp activate integrins by cooperating with talin and induction of cell spreading by directly binding paxillin, BD Biosciences TGFB1I1 antibody (BD Transduction Laboratories, 610051) was used in immunocytochemistry on mouse samples at 1:400 (fig 1) and in western blot on mouse samples at 1:1000 (fig 4). elife (2016) ncbi
mouse monoclonal (349/Paxillin)
  • other; human; loading ...; fig st1
In order to use size exclusion chromatography-microsphere-based affinity proteomics to study clinical samples obtained from pediatric acute leukemia patients, BD Biosciences TGFB1I1 antibody (BD, 349) was used in other on human samples (fig st1). Mol Cell Proteomics (2016) ncbi
mouse monoclonal (349/Paxillin)
  • immunocytochemistry; human; 1:100; loading ...; fig 1a
In order to study Cdc42EP3/BORG2 in cancer-associated fibroblasts, BD Biosciences TGFB1I1 antibody (Transduction labs, 610051) was used in immunocytochemistry on human samples at 1:100 (fig 1a). Cell Rep (2015) ncbi
mouse monoclonal (349/Paxillin)
  • western blot; human; 1:10,000; fig 2
In order to test if SRC, SHP1, and SHP2 target focal adhesions via their SH2 domains, BD Biosciences TGFB1I1 antibody (BD Bioscience, 610052) was used in western blot on human samples at 1:10,000 (fig 2). Sci Rep (2015) ncbi
mouse monoclonal (349/Paxillin)
  • immunocytochemistry; human; fig 5
BD Biosciences TGFB1I1 antibody (BD Transduction, 610052) was used in immunocytochemistry on human samples (fig 5). PLoS ONE (2015) ncbi
mouse monoclonal (349/Paxillin)
  • immunocytochemistry; human; 1:75; loading ...; fig 3b
BD Biosciences TGFB1I1 antibody (BD Pharmingen, 610052) was used in immunocytochemistry on human samples at 1:75 (fig 3b). Nat Commun (2015) ncbi
mouse monoclonal (349/Paxillin)
  • immunocytochemistry; human; 1:400; fig s2
In order to describe a role for talin in sensing tissue stiffness, BD Biosciences TGFB1I1 antibody (BD Transduction Laboratories, 610051) was used in immunocytochemistry on human samples at 1:400 (fig s2). Nat Cell Biol (2015) ncbi
mouse monoclonal (349/Paxillin)
  • immunocytochemistry; human; 1:400; fig s7
In order to characterize the dynamics of a consensus integrin adhesome during adhesion complex assembly and disassembly, BD Biosciences TGFB1I1 antibody (BD Biosciences, 610052) was used in immunocytochemistry on human samples at 1:400 (fig s7). Nat Cell Biol (2015) ncbi
mouse monoclonal (349/Paxillin)
  • western blot; mouse; 1:1000; fig 6c
BD Biosciences TGFB1I1 antibody (BD Biosciences, 612405) was used in western blot on mouse samples at 1:1000 (fig 6c). Endocrinology (2015) ncbi
mouse monoclonal (349/Paxillin)
  • immunocytochemistry; mouse; fig 1, 3
In order to study the role of JNK signaling in the epithelial to mesenchymal transition, BD Biosciences TGFB1I1 antibody (BD, Transduction Laboratories, 610052) was used in immunocytochemistry on mouse samples (fig 1, 3). EMBO J (2015) ncbi
mouse monoclonal (349/Paxillin)
  • immunocytochemistry; mouse; fig 2
BD Biosciences TGFB1I1 antibody (BD Transduction Laboratories, 610051) was used in immunocytochemistry on mouse samples (fig 2). Nat Commun (2015) ncbi
mouse monoclonal (349/Paxillin)
  • western blot; human; 1:1000
In order to study vinculin activation and function, BD Biosciences TGFB1I1 antibody (BD Transduction Labs, 610051) was used in western blot on human samples at 1:1000. Nat Cell Biol (2015) ncbi
mouse monoclonal (349/Paxillin)
  • immunocytochemistry; mouse; fig 4
  • immunocytochemistry; dogs; fig 4
In order to analyze Polycystim-1 and its regulation of microtubular cytoskeleton that favors focal adhesions turnover that regulates migration and cell adhesion, BD Biosciences TGFB1I1 antibody (BD Bioscience, 610052) was used in immunocytochemistry on mouse samples (fig 4) and in immunocytochemistry on dogs samples (fig 4). BMC Cell Biol (2015) ncbi
mouse monoclonal (349/Paxillin)
  • immunocytochemistry; human
In order to determine the mechanism by which ACTN4 drives development of malignant focal adhesions, BD Biosciences TGFB1I1 antibody (BD Biosciences, 610051) was used in immunocytochemistry on human samples . PLoS ONE (2015) ncbi
mouse monoclonal (177/Paxillin)
  • immunoprecipitation; mouse; fig 5
BD Biosciences TGFB1I1 antibody (BD Biosciences, 610569) was used in immunoprecipitation on mouse samples (fig 5). PLoS ONE (2015) ncbi
mouse monoclonal (349/Paxillin)
  • immunocytochemistry; human
BD Biosciences TGFB1I1 antibody (BD BioSciences, BD610052) was used in immunocytochemistry on human samples . Biomaterials (2015) ncbi
mouse monoclonal (349/Paxillin)
  • immunocytochemistry; human; 1:1000
BD Biosciences TGFB1I1 antibody (BD Bioscience, 610052) was used in immunocytochemistry on human samples at 1:1000. J Cell Mol Med (2015) ncbi
mouse monoclonal (349/Paxillin)
  • western blot; mouse; 1:1000; fig 1
  • immunocytochemistry; human; 1:200; fig 6
In order to study phosphorylation events at sites of adhesion, BD Biosciences TGFB1I1 antibody (BD Biosciences, 610051) was used in western blot on mouse samples at 1:1000 (fig 1) and in immunocytochemistry on human samples at 1:200 (fig 6). Nat Commun (2015) ncbi
mouse monoclonal (349/Paxillin)
  • western blot; mouse
In order to investigate the effect of altering the abundance of fibronectin-binding integrins in cell-matrix adhesions on the spatiotemporal organization of force transmission, BD Biosciences TGFB1I1 antibody (Becton Dickinson, 610052) was used in western blot on mouse samples . J Cell Sci (2015) ncbi
mouse monoclonal (349/Paxillin)
  • immunocytochemistry; human; 1:100
  • western blot; human; 1:1000; fig 7
In order to study miR-125a-3p in prostate cancer cells, BD Biosciences TGFB1I1 antibody (BD Transduction Laboratories, 610052) was used in immunocytochemistry on human samples at 1:100 and in western blot on human samples at 1:1000 (fig 7). Oncoscience (2014) ncbi
mouse monoclonal (349/Paxillin)
  • immunocytochemistry; mouse; 1:100; fig 1
BD Biosciences TGFB1I1 antibody (BD Biosciences, 612405) was used in immunocytochemistry on mouse samples at 1:100 (fig 1). Mol Biol Cell (2015) ncbi
mouse monoclonal (349/Paxillin)
  • western blot; human
In order to examine the regulation of integrin-containing adhesion complexes by the microtubule network, BD Biosciences TGFB1I1 antibody (BD Biosciences, 349) was used in western blot on human samples . PLoS ONE (2014) ncbi
mouse monoclonal (349/Paxillin)
  • western blot; human; fig 6
BD Biosciences TGFB1I1 antibody (BD Transduction laboratories, 610051) was used in western blot on human samples (fig 6). EMBO J (2015) ncbi
mouse monoclonal (165/Paxillin)
  • immunocytochemistry; human; 1:100
BD Biosciences TGFB1I1 antibody (BD Transduction Labs, 610619) was used in immunocytochemistry on human samples at 1:100. Clin Cancer Res (2014) ncbi
mouse monoclonal (349/Paxillin)
  • immunocytochemistry; human
BD Biosciences TGFB1I1 antibody (BD Biosciences, 610052) was used in immunocytochemistry on human samples . Oncogene (2015) ncbi
mouse monoclonal (165/Paxillin)
  • immunocytochemistry; human; 1:100
BD Biosciences TGFB1I1 antibody (BD Biosciences, 610620) was used in immunocytochemistry on human samples at 1:100. Breast Cancer Res Treat (2014) ncbi
mouse monoclonal (349/Paxillin)
  • immunocytochemistry; human; 10 ug/ml; fig 2
In order to study actin dynamics during podosome patterning, BD Biosciences TGFB1I1 antibody (BD, 610051) was used in immunocytochemistry on human samples at 10 ug/ml (fig 2). Mol Biol Cell (2014) ncbi
Articles Reviewed
  1. Huebner K, Erlenbach Wuensch K, Prochazka J, Sheraj I, Hampel C, Mrazkova B, et al. ATF2 loss promotes tumor invasion in colorectal cancer cells via upregulation of cancer driver TROP2. Cell Mol Life Sci. 2022;79:423 pubmed publisher
  2. Nataraj N, Noronha A, Lee J, Ghosh S, Mohan Raju H, Sekar A, et al. Nucleoporin-93 reveals a common feature of aggressive breast cancers: robust nucleocytoplasmic transport of transcription factors. Cell Rep. 2022;38:110418 pubmed publisher
  3. Eritja N, Navaridas R, Ruiz Mitjana A, Vidal Sabanés M, Egea J, Encinas M, et al. Endometrial PTEN Deficiency Leads to SMAD2/3 Nuclear Translocation. Cancers (Basel). 2021;13: pubmed publisher
  4. Watson A, Grant A, Parker S, Hill S, Whalen M, Chakrabarti J, et al. Breast tumor stiffness instructs bone metastasis via maintenance of mechanical conditioning. Cell Rep. 2021;35:109293 pubmed publisher
  5. Shelton W, Thomas S, Alexander H, Thomes C, Conway D, Dubash A. Desmoglein-2 harnesses a PDZ-GEF2/Rap1 signaling axis to control cell spreading and focal adhesions independent of cell-cell adhesion. Sci Rep. 2021;11:13295 pubmed publisher
  6. Amado Azevedo J, van Stalborch A, Valent E, Nawaz K, van Bezu J, Eringa E, et al. Depletion of Arg/Abl2 improves endothelial cell adhesion and prevents vascular leak during inflammation. Angiogenesis. 2021;: pubmed publisher
  7. Laly A, Sliogeryte K, Pundel O, Ross R, Keeling M, Avisetti D, et al. The keratin network of intermediate filaments regulates keratinocyte rigidity sensing and nuclear mechanotransduction. Sci Adv. 2021;7: pubmed publisher
  8. Butt B, Owen D, Jeffries C, Ivanova L, Hill C, Houghton J, et al. Insights into herpesvirus assembly from the structure of the pUL7:pUL51 complex. elife. 2020;9: pubmed publisher
  9. Taneja N, Neininger A, Burnette D. Coupling to substrate adhesions drives the maturation of muscle stress fibers into myofibrils within cardiomyocytes. Mol Biol Cell. 2020;31:1273-1288 pubmed publisher
  10. Freeman S, Uderhardt S, Saric A, Collins R, Buckley C, Mylvaganam S, et al. Lipid-gated monovalent ion fluxes regulate endocytic traffic and support immune surveillance. Science. 2020;367:301-305 pubmed publisher
  11. He R, Wang M, Zhao C, Shen M, Yu Y, He L, et al. TFEB-driven autophagy potentiates TGF-β induced migration in pancreatic cancer cells. J Exp Clin Cancer Res. 2019;38:340 pubmed publisher
  12. Kalappurakkal J, Anilkumar A, Patra C, van Zanten T, Sheetz M, Mayor S. Integrin Mechano-chemical Signaling Generates Plasma Membrane Nanodomains that Promote Cell Spreading. Cell. 2019;: pubmed publisher
  13. Ferraro D, Patella F, Zanivan S, Donato C, Aceto N, Giannotta M, et al. Endothelial cell-derived nidogen-1 inhibits migration of SK-BR-3 breast cancer cells. BMC Cancer. 2019;19:312 pubmed publisher
  14. Wang M, Hinton J, Gard J, Garcia J, Knudsen B, Nagle R, et al. Integrin α6β4E variant is associated with actin and CD9 structures and modifies the biophysical properties of cell-cell and cell-extracellular matrix interactions. Mol Biol Cell. 2019;30:838-850 pubmed publisher
  15. Jalal S, Shi S, Acharya V, Huang R, Viasnoff V, Bershadsky A, et al. Actin cytoskeleton self-organization in single epithelial cells and fibroblasts under isotropic confinement. J Cell Sci. 2019;132: pubmed publisher
  16. Lin C, Zhang Y, Zhang K, Zheng Y, Lu L, Chang H, et al. Fever Promotes T Lymphocyte Trafficking via a Thermal Sensory Pathway Involving Heat Shock Protein 90 and α4 Integrins. Immunity. 2019;50:137-151.e6 pubmed publisher
  17. Schell C, Sabass B, Helmstaedter M, Geist F, Abed A, Yasuda Yamahara M, et al. ARP3 Controls the Podocyte Architecture at the Kidney Filtration Barrier. Dev Cell. 2018;47:741-757.e8 pubmed publisher
  18. Baghdadi M, Firmino J, Soni K, Evano B, Di Girolamo D, Mourikis P, et al. Notch-Induced miR-708 Antagonizes Satellite Cell Migration and Maintains Quiescence. Cell Stem Cell. 2018;23:859-868.e5 pubmed publisher
  19. Chen X, Wanggou S, Bodalia A, Zhu M, Dong W, Fan J, et al. A Feedforward Mechanism Mediated by Mechanosensitive Ion Channel PIEZO1 and Tissue Mechanics Promotes Glioma Aggression. Neuron. 2018;100:799-815.e7 pubmed publisher
  20. Frattini V, Pagnotta S, Tala -, Fan J, Russo M, Lee S, et al. A metabolic function of FGFR3-TACC3 gene fusions in cancer. Nature. 2018;553:222-227 pubmed publisher
  21. Rao J, Ashraf S, Tan W, van der Ven A, Gee H, Braun D, et al. Advillin acts upstream of phospholipase C ϵ1 in steroid-resistant nephrotic syndrome. J Clin Invest. 2017;127:4257-4269 pubmed publisher
  22. Gao J, Huang M, Lai J, Mao K, Sun P, Cao Z, et al. Kindlin supports platelet integrin αIIbβ3 activation by interacting with paxillin. J Cell Sci. 2017;130:3764-3775 pubmed publisher
  23. Wu Y, Jhao Y, Cheng Y, Chen Y. 15-Deoxy-?12,14-prostaglandin J2 inhibits migration of human thyroid carcinoma cells by disrupting focal adhesion complex and adherens junction. Oncol Lett. 2017;13:2569-2576 pubmed publisher
  24. Mekhdjian A, Kai F, Rubashkin M, Prahl L, Przybyla L, McGregor A, et al. Integrin-mediated traction force enhances paxillin molecular associations and adhesion dynamics that increase the invasiveness of tumor cells into a three-dimensional extracellular matrix. Mol Biol Cell. 2017;28:1467-1488 pubmed publisher
  25. Heim J, Squirewell E, Neu A, Zocher G, Sominidi Damodaran S, Wyles S, et al. Myosin-1E interacts with FAK proline-rich region 1 to induce fibronectin-type matrix. Proc Natl Acad Sci U S A. 2017;114:3933-3938 pubmed publisher
  26. Zhang W, Gunst S. Non-muscle (NM) myosin heavy chain phosphorylation regulates the formation of NM myosin filaments, adhesome assembly and smooth muscle contraction. J Physiol. 2017;595:4279-4300 pubmed publisher
  27. Yoo S, Latifkar A, Cerione R, Antonyak M. Cool-associated Tyrosine-phosphorylated Protein 1 Is Required for the Anchorage-independent Growth of Cervical Carcinoma Cells by Binding Paxillin and Promoting AKT Activation. J Biol Chem. 2017;292:3947-3957 pubmed publisher
  28. Benito Jardón M, Klapproth S, Gimeno LLuch I, Petzold T, Bharadwaj M, Müller D, et al. The fibronectin synergy site re-enforces cell adhesion and mediates a crosstalk between integrin classes. elife. 2017;6: pubmed publisher
  29. Zeng F, Xie Y, Liao L, Li L, Chen B, Xie J, et al. Biological characterization of three immortalized esophageal epithelial cell lines. Mol Med Rep. 2016;14:4802-4810 pubmed publisher
  30. Yi J, Manna A, Barr V, Hong J, Neuman K, Samelson L. madSTORM: a superresolution technique for large-scale multiplexing at single-molecule accuracy. Mol Biol Cell. 2016;27:3591-3600 pubmed
  31. Frank S, Köllmann C, van Lidth de Jeude J, Thiagarajah J, Engelholm L, Frödin M, et al. The focal adhesion-associated proteins DOCK5 and GIT2 comprise a rheostat in control of epithelial invasion. Oncogene. 2017;36:1816-1828 pubmed publisher
  32. Webb B, White K, Grillo Hill B, Schönichen A, Choi C, Barber D. A Histidine Cluster in the Cytoplasmic Domain of the Na-H Exchanger NHE1 Confers pH-sensitive Phospholipid Binding and Regulates Transporter Activity. J Biol Chem. 2016;291:24096-24104 pubmed
  33. Adam A, Lowery A, Martino N, Alsaffar H, Vincent P. Src Family Kinases Modulate the Loss of Endothelial Barrier Function in Response to TNF-α: Crosstalk with p38 Signaling. PLoS ONE. 2016;11:e0161975 pubmed publisher
  34. Chen R, Wang S, Zhang Y, Hou R, Jiang J, Cui H. CD147 promotes cell motility via upregulation of p190-B RhoGAP in hepatocellular carcinoma. Cancer Cell Int. 2016;16:69 pubmed publisher
  35. Fokkelman M, Balcıoğlu H, Klip J, Yan K, Verbeek F, Danen E, et al. Cellular adhesome screen identifies critical modulators of focal adhesion dynamics, cellular traction forces and cell migration behaviour. Sci Rep. 2016;6:31707 pubmed publisher
  36. Kreger B, Dougherty A, Greene K, Cerione R, Antonyak M. Microvesicle Cargo and Function Changes upon Induction of Cellular Transformation. J Biol Chem. 2016;291:19774-85 pubmed publisher
  37. Taneja N, Fenix A, Rathbun L, Millis B, Tyska M, Hehnly H, et al. Focal adhesions control cleavage furrow shape and spindle tilt during mitosis. Sci Rep. 2016;6:29846 pubmed publisher
  38. Rozo M, Li L, Fan C. Targeting ?1-integrin signaling enhances regeneration in aged and dystrophic muscle in mice. Nat Med. 2016;22:889-96 pubmed publisher
  39. Hashimoto Tane A, Sakuma M, Ike H, Yokosuka T, Kimura Y, Ohara O, et al. Micro-adhesion rings surrounding TCR microclusters are essential for T cell activation. J Exp Med. 2016;213:1609-25 pubmed publisher
  40. Fusté N, Fernández Hernández R, Cemeli T, Mirantes C, Pedraza N, Rafel M, et al. Cytoplasmic cyclin D1 regulates cell invasion and metastasis through the phosphorylation of paxillin. Nat Commun. 2016;7:11581 pubmed publisher
  41. Jadav R, Kumar D, Buwa N, Ganguli S, Thampatty S, Balasubramanian N, et al. Deletion of inositol hexakisphosphate kinase 1 (IP6K1) reduces cell migration and invasion, conferring protection from aerodigestive tract carcinoma in mice. Cell Signal. 2016;28:1124-36 pubmed publisher
  42. Marcos Ramiro B, García Weber D, Barroso S, Feito J, Ortega M, Cernuda Morollón E, et al. RhoB controls endothelial barrier recovery by inhibiting Rac1 trafficking to the cell border. J Cell Biol. 2016;213:385-402 pubmed publisher
  43. Nader G, Ezratty E, Gundersen G. FAK, talin and PIPKI? regulate endocytosed integrin activation to polarize focal adhesion assembly. Nat Cell Biol. 2016;18:491-503 pubmed publisher
  44. Rooney N, Wang P, Brennan K, Gilmore A, Streuli C. The Integrin-Mediated ILK-Parvin-?Pix Signaling Axis Controls Differentiation in Mammary Epithelial Cells. J Cell Physiol. 2016;231:2408-17 pubmed publisher
  45. Hirth S, Bühler A, Bührdel J, Rudeck S, Dahme T, Rottbauer W, et al. Paxillin and Focal Adhesion Kinase (FAK) Regulate Cardiac Contractility in the Zebrafish Heart. PLoS ONE. 2016;11:e0150323 pubmed publisher
  46. Petridou N, Skourides P. A ligand-independent integrin β1 mechanosensory complex guides spindle orientation. Nat Commun. 2016;7:10899 pubmed publisher
  47. Kenific C, Stehbens S, Goldsmith J, Leidal A, Faure N, Ye J, et al. NBR1 enables autophagy-dependent focal adhesion turnover. J Cell Biol. 2016;212:577-90 pubmed publisher
  48. Horton E, Humphries J, Stutchbury B, Jacquemet G, Ballestrem C, Barry S, et al. Modulation of FAK and Src adhesion signaling occurs independently of adhesion complex composition. J Cell Biol. 2016;212:349-64 pubmed publisher
  49. Theodosiou M, Widmaier M, Böttcher R, Rognoni E, Veelders M, Bharadwaj M, et al. Kindlin-2 cooperates with talin to activate integrins and induces cell spreading by directly binding paxillin. elife. 2016;5:e10130 pubmed publisher
  50. Kanderová V, Kuzilkova D, Stuchly J, Vaskova M, Brdicka T, Fiser K, et al. High-resolution Antibody Array Analysis of Childhood Acute Leukemia Cells. Mol Cell Proteomics. 2016;15:1246-61 pubmed publisher
  51. Calvo F, Ranftl R, Hooper S, Farrugia A, Moeendarbary E, Bruckbauer A, et al. Cdc42EP3/BORG2 and Septin Network Enables Mechano-transduction and the Emergence of Cancer-Associated Fibroblasts. Cell Rep. 2015;13:2699-714 pubmed publisher
  52. Wu J, Chen Y, Kuo C, Wenshin Yu H, Chen Y, Chiou A, et al. Focal adhesion kinase-dependent focal adhesion recruitment of SH2 domains directs SRC into focal adhesions to regulate cell adhesion and migration. Sci Rep. 2015;5:18476 pubmed publisher
  53. Yasuda K, Takahashi M, Mori N. Mdm20 Modulates Actin Remodeling through the mTORC2 Pathway via Its Effect on Rictor Expression. PLoS ONE. 2015;10:e0142943 pubmed publisher
  54. Doyle A, Carvajal N, Jin A, Matsumoto K, Yamada K. Local 3D matrix microenvironment regulates cell migration through spatiotemporal dynamics of contractility-dependent adhesions. Nat Commun. 2015;6:8720 pubmed publisher
  55. Austen K, Ringer P, Mehlich A, Chrostek Grashoff A, Kluger C, Klingner C, et al. Extracellular rigidity sensing by talin isoform-specific mechanical linkages. Nat Cell Biol. 2015;17:1597-606 pubmed publisher
  56. Horton E, Byron A, Askari J, Ng D, Millon Frémillon A, Robertson J, et al. Definition of a consensus integrin adhesome and its dynamics during adhesion complex assembly and disassembly. Nat Cell Biol. 2015;17:1577-1587 pubmed publisher
  57. Dong H, Chen Z, Wang C, Xiong Z, Zhao W, Jia C, et al. Rictor Regulates Spermatogenesis by Controlling Sertoli Cell Cytoskeletal Organization and Cell Polarity in the Mouse Testis. Endocrinology. 2015;156:4244-56 pubmed publisher
  58. Sahu S, Garding A, Tiwari N, Thakurela S, Toedling J, Gebhard S, et al. JNK-dependent gene regulatory circuitry governs mesenchymal fate. EMBO J. 2015;34:2162-81 pubmed publisher
  59. Kosmalska A, Casares L, Elosegui Artola A, Thottacherry J, Moreno Vicente R, González Tarragó V, et al. Physical principles of membrane remodelling during cell mechanoadaptation. Nat Commun. 2015;6:7292 pubmed publisher
  60. Case L, Baird M, Shtengel G, Campbell S, Hess H, Davidson M, et al. Molecular mechanism of vinculin activation and nanoscale spatial organization in focal adhesions. Nat Cell Biol. 2015;17:880-92 pubmed publisher
  61. Castelli M, De Pascalis C, Distefano G, Ducano N, Oldani A, Lanzetti L, et al. Regulation of the microtubular cytoskeleton by Polycystin-1 favors focal adhesions turnover to modulate cell adhesion and migration. BMC Cell Biol. 2015;16:15 pubmed publisher
  62. Fukumoto M, Kurisu S, Yamada T, Takenawa T. α-Actinin-4 enhances colorectal cancer cell invasion by suppressing focal adhesion maturation. PLoS ONE. 2015;10:e0120616 pubmed publisher
  63. Fujikawa A, Matsumoto M, Kuboyama K, Suzuki R, Noda M. Specific dephosphorylation at tyr-554 of git1 by ptprz promotes its association with paxillin and hic-5. PLoS ONE. 2015;10:e0119361 pubmed publisher
  64. Toh Y, Xing J, Yu H. Modulation of integrin and E-cadherin-mediated adhesions to spatially control heterogeneity in human pluripotent stem cell differentiation. Biomaterials. 2015;50:87-97 pubmed publisher
  65. Yu H, Chen Y, Huang C, Liu C, Chiou A, Wang Y, et al. β-PIX controls intracellular viscoelasticity to regulate lung cancer cell migration. J Cell Mol Med. 2015;19:934-47 pubmed publisher
  66. Robertson J, Jacquemet G, Byron A, Jones M, Warwood S, Selley J, et al. Defining the phospho-adhesome through the phosphoproteomic analysis of integrin signalling. Nat Commun. 2015;6:6265 pubmed publisher
  67. Balcioglu H, van Hoorn H, Donato D, Schmidt T, Danen E. The integrin expression profile modulates orientation and dynamics of force transmission at cell-matrix adhesions. J Cell Sci. 2015;128:1316-26 pubmed publisher
  68. Ninio Many L, Grossman H, Levi M, Zilber S, Tsarfaty I, Shomron N, et al. MicroRNA miR-125a-3p modulates molecular pathway of motility and migration in prostate cancer cells. Oncoscience. 2014;1:250-261 pubmed
  69. Suraneni P, Fogelson B, Rubinstein B, Noguera P, Volkmann N, Hanein D, et al. A mechanism of leading-edge protrusion in the absence of Arp2/3 complex. Mol Biol Cell. 2015;26:901-12 pubmed publisher
  70. Ng D, Humphries J, Byron A, Millon Frémillon A, Humphries M. Microtubule-dependent modulation of adhesion complex composition. PLoS ONE. 2014;9:e115213 pubmed publisher
  71. Gill M, Turner R, Stevenson P, Way M. KSHV-TK is a tyrosine kinase that disrupts focal adhesions and induces Rho-mediated cell contraction. EMBO J. 2015;34:448-65 pubmed publisher
  72. Sankar S, Theisen E, Bearss J, Mulvihill T, Hoffman L, Sorna V, et al. Reversible LSD1 inhibition interferes with global EWS/ETS transcriptional activity and impedes Ewing sarcoma tumor growth. Clin Cancer Res. 2014;20:4584-97 pubmed publisher
  73. Wang Q, Shen B, Chen L, Zheng P, Feng H, Hao Q, et al. Extracellular calumenin suppresses ERK1/2 signaling and cell migration by protecting fibulin-1 from MMP-13-mediated proteolysis. Oncogene. 2015;34:1006-18 pubmed publisher
  74. Ito M, Hagiyama M, Mimae T, Inoue T, Kato T, Yoneshige A, et al. ?-Parvin, a pseudopodial constituent, promotes cell motility and is associated with lymph node metastasis of lobular breast carcinoma. Breast Cancer Res Treat. 2014;144:59-69 pubmed publisher
  75. Georgess D, Mazzorana M, Terrado J, Delprat C, Chamot C, Guasch R, et al. Comparative transcriptomics reveals RhoE as a novel regulator of actin dynamics in bone-resorbing osteoclasts. Mol Biol Cell. 2014;25:380-96 pubmed publisher