This is a Validated Antibody Database (VAD) review about chicken RAB7A, based on 28 published articles (read how Labome selects the articles), using RAB7A antibody in all methods. It is aimed to help Labome visitors find the most suited RAB7A antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
RAB7A synonym: RAB7; ras-related protein Rab-7a; RAB7, member RAS oncogene family

Abcam
mouse monoclonal (Rab7-117)
  • western blot; human; 1:1000; loading ...; fig 1d
Abcam RAB7A antibody (Abcam, ab50533) was used in western blot on human samples at 1:1000 (fig 1d). elife (2019) ncbi
mouse monoclonal (Rab7-117)
  • immunocytochemistry; human; loading ...; fig 4m
Abcam RAB7A antibody (Abcam, Rab7-117) was used in immunocytochemistry on human samples (fig 4m). Front Immunol (2018) ncbi
mouse monoclonal (Rab7-117)
  • immunocytochemistry; mouse; loading ...; fig s10e
Abcam RAB7A antibody (Abcam, ab50533) was used in immunocytochemistry on mouse samples (fig s10e). Science (2018) ncbi
mouse monoclonal (Rab7-117)
  • immunohistochemistry; mouse; 1:2000; loading ...; fig s5
Abcam RAB7A antibody (Abcam, ab50533) was used in immunohistochemistry on mouse samples at 1:2000 (fig s5). J Clin Invest (2018) ncbi
mouse monoclonal (Rab7-117)
  • western blot; rat; 1:500; loading ...; fig 5e
Abcam RAB7A antibody (Abcam, 50533) was used in western blot on rat samples at 1:500 (fig 5e). J Cell Biol (2017) ncbi
mouse monoclonal (Rab7-117)
  • immunocytochemistry; pig; fig 3d
Abcam RAB7A antibody (Abcam, ab50533) was used in immunocytochemistry on pig samples (fig 3d). Biochim Biophys Acta Mol Cell Biol Lipids (2017) ncbi
mouse monoclonal (Rab7-117)
  • western blot; mouse; fig 8
In order to study the role of CD146 in the formation and retention of macrophage foam cells, Abcam RAB7A antibody (Abcam, ab50533) was used in western blot on mouse samples (fig 8). Cell Res (2017) ncbi
mouse monoclonal (Rab7-117)
  • immunocytochemistry; mouse; loading ...; fig 3g
Abcam RAB7A antibody (Abcam, ab50533) was used in immunocytochemistry on mouse samples (fig 3g). Oncotarget (2016) ncbi
mouse monoclonal (Rab7-117)
  • immunohistochemistry; human; 1:100; loading ...; fig 4e
Abcam RAB7A antibody (Abcam, ab50533) was used in immunohistochemistry on human samples at 1:100 (fig 4e). J Immunol (2016) ncbi
mouse monoclonal (Rab7-117)
  • western blot; mouse; fig 1
In order to mediate direct uptake of RNA by lysosomes by lysosomal putative RNA transporter SIDT2, Abcam RAB7A antibody (Abcam, ab50533) was used in western blot on mouse samples (fig 1). Autophagy (2016) ncbi
mouse monoclonal (Rab7-117)
  • immunocytochemistry; human; 1:1000; fig 4
In order to study how importation of copper into cells is regulated, Abcam RAB7A antibody (Abcam, ab50533) was used in immunocytochemistry on human samples at 1:1000 (fig 4). J Cell Sci (2016) ncbi
mouse monoclonal (Rab7-117)
  • immunocytochemistry; human; loading ...; fig 4
In order to research the involvement of miRNA in cholesterol homeostasis, Abcam RAB7A antibody (Abcam, 50533) was used in immunocytochemistry on human samples (fig 4). Arterioscler Thromb Vasc Biol (2016) ncbi
mouse monoclonal (Rab7-117)
  • immunocytochemistry; mouse; 1:200-1:500; fig 7
Abcam RAB7A antibody (Abcam, ab50533) was used in immunocytochemistry on mouse samples at 1:200-1:500 (fig 7). PLoS Genet (2015) ncbi
mouse monoclonal (Rab7-117)
  • western blot; mouse
In order to assess the effects of an autophagy inducer on col6a1 knock out mice, Abcam RAB7A antibody (Abcam, ab50533) was used in western blot on mouse samples . Autophagy (2015) ncbi
mouse monoclonal (Rab7-117)
  • immunohistochemistry - paraffin section; mouse
Abcam RAB7A antibody (Abcam, Rab7-117) was used in immunohistochemistry - paraffin section on mouse samples . Front Cell Neurosci (2015) ncbi
mouse monoclonal (Rab7-117)
  • immunoprecipitation; mouse
  • western blot; mouse
  • immunoprecipitation; rat
  • western blot; rat
Abcam RAB7A antibody (Abcam, ab50533) was used in immunoprecipitation on mouse samples , in western blot on mouse samples , in immunoprecipitation on rat samples and in western blot on rat samples . J Neurosci (2015) ncbi
mouse monoclonal (Rab7-117)
  • immunocytochemistry; mouse; 1:50; fig 2a
  • western blot; mouse; 1:500; fig 2b
  • immunohistochemistry - paraffin section; human; 1:50; fig 4a
In order to show that C9ORF72 regulates endosomal trafficking, Abcam RAB7A antibody (Abcam, ab50533) was used in immunocytochemistry on mouse samples at 1:50 (fig 2a), in western blot on mouse samples at 1:500 (fig 2b) and in immunohistochemistry - paraffin section on human samples at 1:50 (fig 4a). Hum Mol Genet (2014) ncbi
mouse monoclonal (Rab7-117)
  • western blot; human; fig 3
In order to study the interaction of the TIP47 lipid droplet-binding protein with HCV NS5A and the role of this interaction in the regulation of viral RNA replication, Abcam RAB7A antibody (Abcam, ab50533) was used in western blot on human samples (fig 3). PLoS Pathog (2013) ncbi
mouse monoclonal (Rab7-117)
  • immunocytochemistry; human
Abcam RAB7A antibody (Abcam, ab50533) was used in immunocytochemistry on human samples . FASEB J (2013) ncbi
mouse monoclonal (Rab7-117)
  • immunocytochemistry; dog
  • western blot; dog
Abcam RAB7A antibody (Abcam, ab50533) was used in immunocytochemistry on dog samples and in western blot on dog samples . J Biol Chem (2012) ncbi
GeneTex
mouse monoclonal (Rab7-117)
  • immunocytochemistry; mouse; loading ...; fig s7a
In order to research the role of C9orf72 in macrophage and microglial function, GeneTex RAB7A antibody (GeneTex, GTX 16196) was used in immunocytochemistry on mouse samples (fig s7a). Science (2016) ncbi
Sigma-Aldrich
mouse monoclonal (Rab7-117)
  • immunohistochemistry - paraffin section; mouse; loading ...; fig 3f
Sigma-Aldrich RAB7A antibody (Sigma-Aldrich, R8779) was used in immunohistochemistry - paraffin section on mouse samples (fig 3f). Science (2019) ncbi
mouse monoclonal (Rab7-117)
  • western blot; human; 1:6000; loading ...; fig 3c
Sigma-Aldrich RAB7A antibody (Sigma-Aldrich, R8779) was used in western blot on human samples at 1:6000 (fig 3c). Nat Commun (2017) ncbi
mouse monoclonal (Rab7-117)
  • immunoprecipitation; human; loading ...; fig 6b
  • western blot; human; loading ...; fig 6a
In order to study the mechanism of internalization of CXCR4 receptor dependent on MIM and small Rab GTPases., Sigma-Aldrich RAB7A antibody (Sigma-Aldrich, R8779) was used in immunoprecipitation on human samples (fig 6b) and in western blot on human samples (fig 6a). J Cell Sci (2017) ncbi
mouse monoclonal (Rab7-117)
  • immunocytochemistry; common platanna; fig 1
Sigma-Aldrich RAB7A antibody (Sigma, R8779) was used in immunocytochemistry on common platanna samples (fig 1). Open Biol (2016) ncbi
mouse monoclonal (Rab7-117)
  • immunocytochemistry; fruit fly; 1:200; fig 3f
In order to analyze protein kinase LRRK2, parkinson's disease associated, which modulates notch signaling via the endosomal pathway, Sigma-Aldrich RAB7A antibody (Sigma-Aldrich, Rab7-117) was used in immunocytochemistry on fruit fly samples at 1:200 (fig 3f). PLoS Genet (2015) ncbi
mouse monoclonal (Rab7-117)
  • immunohistochemistry - paraffin section; mouse; fig 5b
  • immunohistochemistry - paraffin section; human; fig 5a
  • immunocytochemistry; human; fig 1
  • western blot; human; fig 4
In order to analyze early stages of melanoma development driven by PI3K macropinocytosis and counteracted by RAB7, Sigma-Aldrich RAB7A antibody (Sigma, RAB7-117) was used in immunohistochemistry - paraffin section on mouse samples (fig 5b), in immunohistochemistry - paraffin section on human samples (fig 5a), in immunocytochemistry on human samples (fig 1) and in western blot on human samples (fig 4). Oncotarget (2015) ncbi
mouse monoclonal (Rab7-117)
  • immunocytochemistry; human; fig 6
In order to discover that Myosin Vc contributes to melanosome biogenesis via Rab GTPases, Sigma-Aldrich RAB7A antibody (Sigma, Rab7-117) was used in immunocytochemistry on human samples (fig 6). J Biol Chem (2014) ncbi
Articles Reviewed
  1. Ladinsky M, Araujo L, Zhang X, Veltri J, Galán Díez M, Soualhi S, et al. Endocytosis of commensal antigens by intestinal epithelial cells regulates mucosal T cell homeostasis. Science. 2019;363: pubmed publisher
  2. Yeshaw W, van der Zwaag M, Pinto F, Lahaye L, Faber A, Gómez Sánchez R, et al. Human VPS13A is associated with multiple organelles and influences mitochondrial morphology and lipid droplet motility. elife. 2019;8: pubmed publisher
  3. Swain S, Roe M, Sebrell T, Sidar B, Dankoff J, VanAusdol R, et al. CD103 (αE Integrin) Undergoes Endosomal Trafficking in Human Dendritic Cells, but Does Not Mediate Epithelial Adhesion. Front Immunol. 2018;9:2989 pubmed publisher
  4. Theisen D, Davidson J, Briseño C, Gargaro M, Lauron E, Wang Q, et al. WDFY4 is required for cross-presentation in response to viral and tumor antigens. Science. 2018;362:694-699 pubmed publisher
  5. Alissafi T, Hatzioannou A, Mintzas K, Barouni R, Banos A, Sormendi S, et al. Autophagy orchestrates the regulatory program of tumor-associated myeloid-derived suppressor cells. J Clin Invest. 2018;128:3840-3852 pubmed publisher
  6. Laviolette L, Mermoud J, Calvo I, Olson N, Boukhali M, Steinlein O, et al. Negative regulation of EGFR signalling by the human folliculin tumour suppressor protein. Nat Commun. 2017;8:15866 pubmed publisher
  7. Zhang X, Jiang S, Mitok K, Li L, Attie A, Martin T. BAIAP3, a C2 domain-containing Munc13 protein, controls the fate of dense-core vesicles in neuroendocrine cells. J Cell Biol. 2017;216:2151-2166 pubmed publisher
  8. Kober A, Manavalan A, Tam Amersdorfer C, Holmér A, Saeed A, Fanaee Danesh E, et al. Implications of cerebrovascular ATP-binding cassette transporter G1 (ABCG1) and apolipoprotein M in cholesterol transport at the blood-brain barrier. Biochim Biophys Acta Mol Cell Biol Lipids. 2017;1862:573-588 pubmed publisher
  9. Li L, Baxter S, Gu N, Ji M, Zhan X. Missing-in-metastasis protein downregulates CXCR4 by promoting ubiquitylation and interaction with small Rab GTPases. J Cell Sci. 2017;130:1475-1485 pubmed publisher
  10. Luo Y, Duan H, Qian Y, Feng L, Wu Z, Wang F, et al. Macrophagic CD146 promotes foam cell formation and retention during atherosclerosis. Cell Res. 2017;27:352-372 pubmed publisher
  11. Konopacki F, Wong H, Dwivedy A, Bellon A, Blower M, Holt C. ESCRT-II controls retinal axon growth by regulating DCC receptor levels and local protein synthesis. Open Biol. 2016;6:150218 pubmed publisher
  12. Wang Y, Hu C, Li J, You X, Gao F. Increased translocation of antigens to endosomes and TLR4 mediated endosomal recruitment of TAP contribute to nicotine augmented cross-presentation. Oncotarget. 2016;7:38451-38466 pubmed publisher
  13. Scharn C, Collins A, Nair V, Stamm C, MARCIANO D, Graviss E, et al. Heme Oxygenase-1 Regulates Inflammation and Mycobacterial Survival in Human Macrophages during Mycobacterium tuberculosis Infection. J Immunol. 2016;196:4641-9 pubmed publisher
  14. Aizawa S, Fujiwara Y, Contu V, Hase K, Takahashi M, Kikuchi H, et al. Lysosomal putative RNA transporter SIDT2 mediates direct uptake of RNA by lysosomes. Autophagy. 2016;12:565-78 pubmed publisher
  15. O Rourke J, Bogdanik L, Yáñez A, Lall D, Wolf A, Muhammad A, et al. C9orf72 is required for proper macrophage and microglial function in mice. Science. 2016;351:1324-9 pubmed publisher
  16. Clifford R, Maryon E, Kaplan J. Dynamic internalization and recycling of a metal ion transporter: Cu homeostasis and CTR1, the human Cu⁺ uptake system. J Cell Sci. 2016;129:1711-21 pubmed publisher
  17. Ouimet M, Hennessy E, van Solingen C, Koelwyn G, Hussein M, Ramkhelawon B, et al. miRNA Targeting of Oxysterol-Binding Protein-Like 6 Regulates Cholesterol Trafficking and Efflux. Arterioscler Thromb Vasc Biol. 2016;36:942-951 pubmed publisher
  18. Drusenheimer N, Migdal B, Jäckel S, Tveriakhina L, Scheider K, Schulz K, et al. The Mammalian Orthologs of Drosophila Lgd, CC2D1A and CC2D1B, Function in the Endocytic Pathway, but Their Individual Loss of Function Does Not Affect Notch Signalling. PLoS Genet. 2015;11:e1005749 pubmed publisher
  19. Chrisam M, Pirozzi M, Castagnaro S, Blaauw B, Polishchuck R, Cecconi F, et al. Reactivation of autophagy by spermidine ameliorates the myopathic defects of collagen VI-null mice. Autophagy. 2015;11:2142-52 pubmed publisher
  20. Imai Y, Kobayashi Y, Inoshita T, Meng H, Arano T, Uemura K, et al. The Parkinson's Disease-Associated Protein Kinase LRRK2 Modulates Notch Signaling through the Endosomal Pathway. PLoS Genet. 2015;11:e1005503 pubmed publisher
  21. Alonso Curbelo D, Osterloh L, Cañón E, Calvo T, Martínez Herranz R, Karras P, et al. RAB7 counteracts PI3K-driven macropinocytosis activated at early stages of melanoma development. Oncotarget. 2015;6:11848-62 pubmed
  22. La Rosa L, Perrone L, Nielsen M, Calissano P, Andersen O, Matrone C. Y682G Mutation of Amyloid Precursor Protein Promotes Endo-Lysosomal Dysfunction by Disrupting APP-SorLA Interaction. Front Cell Neurosci. 2015;9:109 pubmed publisher
  23. Fields J, Dumaop W, Eleuteri S, Elueteri S, Campos S, Serger E, et al. HIV-1 Tat alters neuronal autophagy by modulating autophagosome fusion to the lysosome: implications for HIV-associated neurocognitive disorders. J Neurosci. 2015;35:1921-38 pubmed publisher
  24. Bultema J, Boyle J, Malenke P, Martin F, Dell Angelica E, Cheney R, et al. Myosin vc interacts with Rab32 and Rab38 proteins and works in the biogenesis and secretion of melanosomes. J Biol Chem. 2014;289:33513-28 pubmed publisher
  25. Farg M, Sundaramoorthy V, Sultana J, Yang S, Atkinson R, Levina V, et al. C9ORF72, implicated in amytrophic lateral sclerosis and frontotemporal dementia, regulates endosomal trafficking. Hum Mol Genet. 2014;23:3579-95 pubmed publisher
  26. Vogt D, Camus G, Herker E, Webster B, Tsou C, Greene W, et al. Lipid droplet-binding protein TIP47 regulates hepatitis C Virus RNA replication through interaction with the viral NS5A protein. PLoS Pathog. 2013;9:e1003302 pubmed publisher
  27. Wu H, Downs D, Ghosh K, Ghosh A, Staib P, Monod M, et al. Candida albicans secreted aspartic proteases 4-6 induce apoptosis of epithelial cells by a novel Trojan horse mechanism. FASEB J. 2013;27:2132-44 pubmed publisher
  28. Cho K, Park J, Piggott A, Salim A, Gorfe A, Parton R, et al. Staurosporines disrupt phosphatidylserine trafficking and mislocalize Ras proteins. J Biol Chem. 2012;287:43573-84 pubmed publisher