This is a Validated Antibody Database (VAD) review about chicken PRKAR2A, based on 18 published articles (read how Labome selects the articles), using PRKAR2A antibody in all methods. It is aimed to help Labome visitors find the most suited PRKAR2A antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
PRKAR2A synonym: cAMP-dependent protein kinase type II-alpha regulatory subunit; protein kinase, cAMP-dependent, regulatory, type II, alpha

Knockout validation
BD Biosciences
mouse monoclonal (45)
  • immunohistochemistry knockout validation; mouse; fig 4
  • western blot knockout validation; mouse; fig s2
BD Biosciences PRKAR2A antibody (BD Bioscience, 610626) was used in immunohistochemistry knockout validation on mouse samples (fig 4) and in western blot knockout validation on mouse samples (fig s2). Nat Commun (2015) ncbi
BD Biosciences
mouse monoclonal (45)
  • western blot; human; 0.8 ug/ml; loading ...; fig s2d
BD Biosciences PRKAR2A antibody (BD Biosciences, 610626) was used in western blot on human samples at 0.8 ug/ml (fig s2d). Proc Natl Acad Sci U S A (2017) ncbi
mouse monoclonal (45)
  • western blot; mouse; loading ...; fig 6a
BD Biosciences PRKAR2A antibody (BD Biosciences, 610625) was used in western blot on mouse samples (fig 6a). Diabetes (2017) ncbi
mouse monoclonal (45)
  • immunocytochemistry; mouse; 1:3000; loading ...; fig 1e
BD Biosciences PRKAR2A antibody (BD Biosciences, 610625) was used in immunocytochemistry on mouse samples at 1:3000 (fig 1e). PLoS ONE (2017) ncbi
mouse monoclonal (45)
  • western blot; human; 1:1000; fig 2a
BD Biosciences PRKAR2A antibody (BD, 610625) was used in western blot on human samples at 1:1000 (fig 2a). Sci Rep (2017) ncbi
mouse monoclonal (45)
  • western blot; human; 1:1000; loading ...; fig 4c
  • immunocytochemistry; dog; 1:200; loading ...; fig s3a
In order to elucidate the mechanisms by which ARHGAP36 blocks protein kinase A signaling, BD Biosciences PRKAR2A antibody (BD, 610626) was used in western blot on human samples at 1:1000 (fig 4c) and in immunocytochemistry on dog samples at 1:200 (fig s3a). Nat Commun (2016) ncbi
mouse monoclonal (45)
  • western blot; human; fig 1
BD Biosciences PRKAR2A antibody (BD Bioscience, 610626) was used in western blot on human samples (fig 1). Proc Natl Acad Sci U S A (2016) ncbi
mouse monoclonal (45)
  • western blot; human; fig 2
BD Biosciences PRKAR2A antibody (BD Biosciences, 610626) was used in western blot on human samples (fig 2). Pediatr Res (2016) ncbi
mouse monoclonal (45)
  • other; human; loading ...; fig st1
In order to use size exclusion chromatography-microsphere-based affinity proteomics to study clinical samples obtained from pediatric acute leukemia patients, BD Biosciences PRKAR2A antibody (BD, 45) was used in other on human samples (fig st1). Mol Cell Proteomics (2016) ncbi
mouse monoclonal (45)
  • immunohistochemistry - free floating section; mouse; 1:3000; loading ...; tbl 1
BD Biosciences PRKAR2A antibody (BD Biosciences, 610625) was used in immunohistochemistry - free floating section on mouse samples at 1:3000 (tbl 1). J Comp Neurol (2016) ncbi
mouse monoclonal (45)
  • immunoprecipitation; mouse; 1:500; fig 2b
  • western blot; mouse; fig 2a
BD Biosciences PRKAR2A antibody (BD Transduction Laboratories, 45 RUO) was used in immunoprecipitation on mouse samples at 1:500 (fig 2b) and in western blot on mouse samples (fig 2a). Transl Psychiatry (2015) ncbi
mouse monoclonal (45)
  • western blot; human; fig 3
BD Biosciences PRKAR2A antibody (BD Biosciences, 610626) was used in western blot on human samples (fig 3). Front Pharmacol (2015) ncbi
mouse monoclonal (45)
  • immunohistochemistry knockout validation; mouse; fig 4
  • western blot knockout validation; mouse; fig s2
BD Biosciences PRKAR2A antibody (BD Bioscience, 610626) was used in immunohistochemistry knockout validation on mouse samples (fig 4) and in western blot knockout validation on mouse samples (fig s2). Nat Commun (2015) ncbi
mouse monoclonal (45)
  • western blot; mouse; 1:1000; fig 4e
BD Biosciences PRKAR2A antibody (BD Transduction Laboratories, 610625) was used in western blot on mouse samples at 1:1000 (fig 4e). Mol Metab (2015) ncbi
mouse monoclonal (45)
  • western blot; human
In order to study PDE3 in human cardiac myocytes, BD Biosciences PRKAR2A antibody (BD Biosciences, 610626) was used in western blot on human samples . J Biol Chem (2015) ncbi
mouse monoclonal (45)
  • immunohistochemistry; mouse; 1:3,000
BD Biosciences PRKAR2A antibody (BD Biosciences, 610626) was used in immunohistochemistry on mouse samples at 1:3,000. Dev Cell (2014) ncbi
mouse monoclonal (45)
  • immunocytochemistry; mouse; 1:500
BD Biosciences PRKAR2A antibody (BD Biosciences, 610625) was used in immunocytochemistry on mouse samples at 1:500. PLoS ONE (2013) ncbi
mouse monoclonal (45)
  • immunohistochemistry - frozen section; mouse; 1:2000
BD Biosciences PRKAR2A antibody (BD Bioscience, 610625) was used in immunohistochemistry - frozen section on mouse samples at 1:2000. J Comp Neurol (2013) ncbi
mouse monoclonal (45)
  • immunohistochemistry; thirteen-lined ground squirrel; 1:500
BD Biosciences PRKAR2A antibody (BD Transduction Laboratories, 610625) was used in immunohistochemistry on thirteen-lined ground squirrel samples at 1:500. J Comp Neurol (2012) ncbi
Articles Reviewed
  1. Walker Gray R, Stengel F, Gold M. Mechanisms for restraining cAMP-dependent protein kinase revealed by subunit quantitation and cross-linking approaches. Proc Natl Acad Sci U S A. 2017;114:10414-10419 pubmed publisher
  2. Kuo T, Chen T, Lee R, Nguyen N, Broughton A, Zhang D, et al. Pik3r1 Is Required for Glucocorticoid-Induced Perilipin 1 Phosphorylation in Lipid Droplet for Adipocyte Lipolysis. Diabetes. 2017;66:1601-1610 pubmed publisher
  3. Puller C, Arbogast P, Keeley P, Reese B, Haverkamp S. Dendritic stratification differs among retinal OFF bipolar cell types in the absence of rod photoreceptors. PLoS ONE. 2017;12:e0173455 pubmed publisher
  4. Weigand I, Ronchi C, Rizk Rabin M, Dalmazi G, Wild V, Bathon K, et al. Differential expression of the protein kinase A subunits in normal adrenal glands and adrenocortical adenomas. Sci Rep. 2017;7:49 pubmed publisher
  5. Eccles R, Czajkowski M, Barth C, Müller P, McShane E, Grunwald S, et al. Bimodal antagonism of PKA signalling by ARHGAP36. Nat Commun. 2016;7:12963 pubmed publisher
  6. Bachmann V, Mayrhofer J, Ilouz R, Tschaikner P, Raffeiner P, Röck R, et al. Gpr161 anchoring of PKA consolidates GPCR and cAMP signaling. Proc Natl Acad Sci U S A. 2016;113:7786-91 pubmed publisher
  7. Riggle K, Riehle K, Kenerson H, Turnham R, Homma M, Kazami M, et al. Enhanced cAMP-stimulated protein kinase A activity in human fibrolamellar hepatocellular carcinoma. Pediatr Res. 2016;80:110-8 pubmed publisher
  8. Kanderová V, Kuzilkova D, Stuchly J, Vaskova M, Brdicka T, Fiser K, et al. High-resolution Antibody Array Analysis of Childhood Acute Leukemia Cells. Mol Cell Proteomics. 2016;15:1246-61 pubmed publisher
  9. Farshi P, Fyk Kolodziej B, Krolewski D, Walker P, Ichinose T. Dopamine D1 receptor expression is bipolar cell type-specific in the mouse retina. J Comp Neurol. 2016;524:2059-79 pubmed publisher
  10. Corcoran K, Leaderbrand K, Jovasevic V, Guedea A, Kassam F, Radulovic J. Regulation of fear extinction versus other affective behaviors by discrete cortical scaffolding complexes associated with NR2B and PKA signaling. Transl Psychiatry. 2015;5:e657 pubmed publisher
  11. Gerbaud P, Taskén K, Pidoux G. Spatiotemporal regulation of cAMP signaling controls the human trophoblast fusion. Front Pharmacol. 2015;6:202 pubmed publisher
  12. Yang L, McKnight G. Hypothalamic PKA regulates leptin sensitivity and adiposity. Nat Commun. 2015;6:8237 pubmed publisher
  13. Rajan S, Dickson L, Mathew E, Orr C, Ellenbroek J, Philipson L, et al. Chronic hyperglycemia downregulates GLP-1 receptor signaling in pancreatic β-cells via protein kinase A. Mol Metab. 2015;4:265-76 pubmed publisher
  14. Ahmad F, Shen W, Vandeput F, Szabo Fresnais N, Krall J, Degerman E, et al. Regulation of sarcoplasmic reticulum Ca2+ ATPase 2 (SERCA2) activity by phosphodiesterase 3A (PDE3A) in human myocardium: phosphorylation-dependent interaction of PDE3A1 with SERCA2. J Biol Chem. 2015;290:6763-76 pubmed publisher
  15. Keeley P, Whitney I, Madsen N, St John A, Borhanian S, Leong S, et al. Independent genomic control of neuronal number across retinal cell types. Dev Cell. 2014;30:103-9 pubmed publisher
  16. Huang Y, Kao J, Tseng D, Chen W, Chiang M, Hwang E. Microtubule-associated type II protein kinase A is important for neurite elongation. PLoS ONE. 2013;8:e73890 pubmed publisher
  17. Kranz K, Dorgau B, Pottek M, Herrling R, Schultz K, Bolte P, et al. Expression of Pannexin1 in the outer plexiform layer of the mouse retina and physiological impact of its knockout. J Comp Neurol. 2013;521:1119-35 pubmed publisher
  18. Light A, Zhu Y, Shi J, Saszik S, Lindstrom S, Davidson L, et al. Organizational motifs for ground squirrel cone bipolar cells. J Comp Neurol. 2012;520:2864-87 pubmed publisher