This is a Validated Antibody Database (VAD) review about chicken HSPA2, based on 11 published articles (read how Labome selects the articles), using HSPA2 antibody in all methods. It is aimed to help Labome visitors find the most suited HSPA2 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
HSPA2 synonym: HSP70; heat shock 70 kDa protein; dnaK-type molecular chaperone; heat shock protein 70

Knockout validation
Enzo Life Sciences
mouse monoclonal (N27F3-4)
  • western blot knockout validation; mouse; 1:2000
In order to investigate the impact of autophagy on photoreceptors, Enzo Life Sciences HSPA2 antibody (Enzo, ADI-SPA-820) was used in western blot knockout validation on mouse samples at 1:2000. Cell Death Differ (2015) ncbi
Enzo Life Sciences
mouse monoclonal (N27F3-4)
  • western blot; human; 1:1000; loading ...; fig 6a
Enzo Life Sciences HSPA2 antibody (Enzo, N27F3-4) was used in western blot on human samples at 1:1000 (fig 6a). Sci Rep (2018) ncbi
mouse monoclonal (N27F3-4)
  • western blot; human; 1:2000; loading ...; fig sf10a
In order to describe a function for NQO1 in stabilizing HIF-1alpha, Enzo Life Sciences HSPA2 antibody (Stratagene, ADI-SPA-820D) was used in western blot on human samples at 1:2000 (fig sf10a). Nat Commun (2016) ncbi
mouse monoclonal (N27F3-4)
  • western blot; Nicotiana benthamiana; fig 1b
Enzo Life Sciences HSPA2 antibody (Enzo Life Sciences, ADI-SPA-820-F) was used in western blot on Nicotiana benthamiana samples (fig 1b). J Virol (2017) ncbi
mouse monoclonal (N27F3-4)
  • western blot; mouse; 1:1000; fig 4
Enzo Life Sciences HSPA2 antibody (ENZO, N27F3-4) was used in western blot on mouse samples at 1:1000 (fig 4). MBio (2016) ncbi
mouse monoclonal (N27F3-4)
  • western blot; mouse; fig 4b
In order to use gene therapy to generate a receptor fusion protein that targets IL-6, Enzo Life Sciences HSPA2 antibody (Enzo Life Sciences, ADI-SPA-820) was used in western blot on mouse samples (fig 4b). Sci Rep (2015) ncbi
mouse monoclonal (N27F3-4)
  • western blot; mouse; 1:1000; fig 5
Enzo Life Sciences HSPA2 antibody (Enzo Life Sciences, ADI-SPA-820) was used in western blot on mouse samples at 1:1000 (fig 5). Mol Med Rep (2015) ncbi
mouse monoclonal (N27F3-4)
  • western blot knockout validation; mouse; 1:2000
In order to investigate the impact of autophagy on photoreceptors, Enzo Life Sciences HSPA2 antibody (Enzo, ADI-SPA-820) was used in western blot knockout validation on mouse samples at 1:2000. Cell Death Differ (2015) ncbi
mouse monoclonal (N27F3-4)
  • western blot; mouse; 1:1000
In order to determine the effect of STA-2842 on liver size and cystic burden in Pkd-/- mice with established polycystic liver disease, Enzo Life Sciences HSPA2 antibody (Enzo, ADI-SPA-820) was used in western blot on mouse samples at 1:1000. PLoS ONE (2014) ncbi
mouse monoclonal (N27F3-4)
  • flow cytometry; human
Enzo Life Sciences HSPA2 antibody (Alexis Biochemicals, ADI-SPA-820PE-D) was used in flow cytometry on human samples . Cytometry A (2014) ncbi
mouse monoclonal (N27F3-4)
  • western blot; human; 1:1000
Enzo Life Sciences HSPA2 antibody (Enzo Life Sciences, ADI-SPA-820-D) was used in western blot on human samples at 1:1000. Oncogene (2013) ncbi
mouse monoclonal (N27F3-4)
  • western blot; rat
In order to investigate the mechanism for neuronal nitric-oxide synthase activity and degradation, Enzo Life Sciences HSPA2 antibody (Enzo Life Sciences, N27F3-4) was used in western blot on rat samples . J Biol Chem (2012) ncbi
Articles Reviewed
  1. Tamaki Y, Shodai A, Morimura T, Hikiami R, Minamiyama S, Ayaki T, et al. Elimination of TDP-43 inclusions linked to amyotrophic lateral sclerosis by a misfolding-specific intrabody with dual proteolytic signals. Sci Rep. 2018;8:6030 pubmed publisher
  2. Oh E, Kim J, Kim J, Kim S, Lee J, Hong S, et al. NQO1 inhibits proteasome-mediated degradation of HIF-1α. Nat Commun. 2016;7:13593 pubmed publisher
  3. Alam S, Rochon D. Evidence that Hsc70 Is Associated with Cucumber Necrosis Virus Particles and Plays a Role in Particle Disassembly. J Virol. 2017;91: pubmed publisher
  4. Liu S, Hossinger A, Hofmann J, Denner P, Vorberg I. Horizontal Transmission of Cytosolic Sup35 Prions by Extracellular Vesicles. MBio. 2016;7: pubmed publisher
  5. Görtz D, Braun G, Maruta Y, Djudjaj S, van Roeyen C, Martin I, et al. Anti-interleukin-6 therapy through application of a monogenic protein inhibitor via gene delivery. Sci Rep. 2015;5:14685 pubmed publisher
  6. Jiang Q, Zhang Z, Li S, Wang Z, Ma Y, Hu Y. Defective heat shock factor 1 inhibits the growth of fibrosarcoma derived from simian virus 40/T antigen‑transformed MEF cells. Mol Med Rep. 2015;12:6517-26 pubmed publisher
  7. Zhou Z, Doggett T, Sene A, Apte R, Ferguson T. Autophagy supports survival and phototransduction protein levels in rod photoreceptors. Cell Death Differ. 2015;22:488-98 pubmed publisher
  8. Smithline Z, Nikonova A, Hensley H, Cai K, Egleston B, Proia D, et al. Inhibiting heat shock protein 90 (HSP90) limits the formation of liver cysts induced by conditional deletion of Pkd1 in mice. PLoS ONE. 2014;9:e114403 pubmed publisher
  9. Cao F, Xu L, Zhang X, Wang Y, Li M, Uzan G, et al. IP-FCM platform detects the existence and regulator-caused dissociation of components in naturally assembled HSP90 complex. Cytometry A. 2014;85:359-67 pubmed publisher
  10. Chatain N, Ziegler P, Fahrenkamp D, Jost E, Moriggl R, Schmitz Van de Leur H, et al. Src family kinases mediate cytoplasmic retention of activated STAT5 in BCR-ABL-positive cells. Oncogene. 2013;32:3587-97 pubmed publisher
  11. Peng H, Morishima Y, Pratt W, Osawa Y. Modulation of heme/substrate binding cleft of neuronal nitric-oxide synthase (nNOS) regulates binding of Hsp90 and Hsp70 proteins and nNOS ubiquitination. J Biol Chem. 2012;287:1556-65 pubmed publisher