This is a Validated Antibody Database (VAD) review about chicken HIST1H46L6, based on 30 published articles (read how Labome selects the articles), using HIST1H46L6 antibody in all methods. It is aimed to help Labome visitors find the most suited HIST1H46L6 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
HIST1H46L6 synonym: histone H4; histone cluster 1, H4-IV, germinal H4-like 6 (similar to human histone cluster 1, class H4 genes)

EMD Millipore
rabbit monoclonal (62-141-13)
  • western blot; human; loading ...; fig s4c
EMD Millipore HIST1H46L6 antibody (Merck, 05-858) was used in western blot on human samples (fig s4c). Cell (2018) ncbi
rabbit polyclonal
  • western blot; mouse; loading ...; fig s3a
EMD Millipore HIST1H46L6 antibody (Millipore, 07-108) was used in western blot on mouse samples (fig s3a). Science (2018) ncbi
rabbit monoclonal (62-141-13)
  • western blot; mouse; loading ...; fig 1b
EMD Millipore HIST1H46L6 antibody (Upstate Biotechnology, 05-858) was used in western blot on mouse samples (fig 1b). Proc Natl Acad Sci U S A (2017) ncbi
rabbit monoclonal (62-141-13)
  • ChIP-Seq; mouse; loading ...; fig s3h
In order to investigate the involvement of acetyl-CoA synthetase in histone acetylation and hippocampal memory, EMD Millipore HIST1H46L6 antibody (Millipore, 05-858) was used in ChIP-Seq on mouse samples (fig s3h). Nature (2017) ncbi
rabbit polyclonal
  • western blot; human; 1:100; loading ...; fig 1d
EMD Millipore HIST1H46L6 antibody (Millipore, 07-108) was used in western blot on human samples at 1:100 (fig 1d). Mol Cell Proteomics (2017) ncbi
rabbit monoclonal (62-141-13)
  • chromatin immunoprecipitation; mouse; loading ...; fig 8
  • western blot; mouse; loading ...; fig 8a
EMD Millipore HIST1H46L6 antibody (EMD Millipore, 05-858) was used in chromatin immunoprecipitation on mouse samples (fig 8) and in western blot on mouse samples (fig 8a). J Exp Med (2016) ncbi
rabbit monoclonal (62-141-13)
  • western blot; human; 1:3000; loading ...; fig s14
EMD Millipore HIST1H46L6 antibody (Millipore, 05-858) was used in western blot on human samples at 1:3000 (fig s14). Nat Commun (2016) ncbi
rabbit polyclonal
  • western blot; human; loading ...; fig 5c
EMD Millipore HIST1H46L6 antibody (Millipore, 07-108) was used in western blot on human samples (fig 5c). Exp Mol Med (2016) ncbi
rabbit monoclonal (62-141-13)
  • western blot; mouse; loading ...; fig 8b
In order to examine the role of BRPF1 during hematopoiesis, EMD Millipore HIST1H46L6 antibody (Millipore, 05-858) was used in western blot on mouse samples (fig 8b). J Clin Invest (2016) ncbi
rabbit polyclonal
  • chromatin immunoprecipitation; human; fig 5
  • western blot; human; fig 5
EMD Millipore HIST1H46L6 antibody (Millipore, MM07-108) was used in chromatin immunoprecipitation on human samples (fig 5) and in western blot on human samples (fig 5). Nat Commun (2016) ncbi
rabbit polyclonal
  • western blot; human; 1:1000; fig 1
EMD Millipore HIST1H46L6 antibody (Millipore, 07-108) was used in western blot on human samples at 1:1000 (fig 1). Mol Med Rep (2016) ncbi
rabbit monoclonal (62-141-13)
  • western blot; human; fig 1
In order to analyze G2 checkpoint regulators for hypoxia-induced alterations, EMD Millipore HIST1H46L6 antibody (Millipore, 05-858) was used in western blot on human samples (fig 1). Mol Oncol (2016) ncbi
rabbit monoclonal (62-141-13)
  • western blot; human; fig 3
In order to characterize modulation of microtubular structure and HSP90alpha chaperone activity against prostate cancer by 4-hydroxybenzoic acid derivatives as HDAC6-specific inhibitors, EMD Millipore HIST1H46L6 antibody (Merck Millipore, 05-858) was used in western blot on human samples (fig 3). Biochem Pharmacol (2016) ncbi
rabbit polyclonal
  • western blot; mouse
EMD Millipore HIST1H46L6 antibody (Millipore, 07-108) was used in western blot on mouse samples . Neurobiol Aging (2015) ncbi
rabbit polyclonal
  • western blot; human; 1:1000; fig 7
EMD Millipore HIST1H46L6 antibody (Millipore, 07-108) was used in western blot on human samples at 1:1000 (fig 7). Cancer Biol Ther (2015) ncbi
rabbit polyclonal
  • western blot; human; 1:250; fig 6
EMD Millipore HIST1H46L6 antibody (Millipore, 07-108) was used in western blot on human samples at 1:250 (fig 6). Nat Commun (2015) ncbi
rabbit polyclonal
  • chromatin immunoprecipitation; mouse; fig s7
EMD Millipore HIST1H46L6 antibody (Upstate, 07-108) was used in chromatin immunoprecipitation on mouse samples (fig s7). Nat Commun (2015) ncbi
rabbit polyclonal
  • western blot; human; fig  8
In order to demonstrate that edimethylaminoparthenolide is an epigenetic modulator and acts in a NF-kappaB-dependent and -independent manner, EMD Millipore HIST1H46L6 antibody (Upstate Biotechnology/Millipore, 07-108) was used in western blot on human samples (fig  8). Cell Death Dis (2015) ncbi
rabbit polyclonal
  • immunocytochemistry; human
EMD Millipore HIST1H46L6 antibody (Millipore, 07-108) was used in immunocytochemistry on human samples . Int J Mol Sci (2014) ncbi
rabbit monoclonal (62-141-13)
  • western blot; baker's yeast; fig 5
EMD Millipore HIST1H46L6 antibody (Upstate, 05-858) was used in western blot on baker's yeast samples (fig 5). Nucleus (2014) ncbi
rabbit polyclonal
  • western blot; human
EMD Millipore HIST1H46L6 antibody (Millipore, 07-108) was used in western blot on human samples . Mol Cell Biochem (2014) ncbi
rabbit monoclonal (62-141-13)
  • western blot; fission yeast
In order to study the mechanism by which Mit1 remodels chromatin to suppress gene transcription, EMD Millipore HIST1H46L6 antibody (Millipore, 05-858) was used in western blot on fission yeast samples . Mol Cell Biol (2014) ncbi
rabbit monoclonal (62-141-13)
  • western blot; human; 1:1000; fig 1f
In order to use nascent chromatin capture to profile chromatin proteome dynamics during replication in human cells, EMD Millipore HIST1H46L6 antibody (Millipore, 05-858) was used in western blot on human samples at 1:1000 (fig 1f). Nat Cell Biol (2014) ncbi
rabbit monoclonal (62-141-13)
  • chromatin immunoprecipitation; human
EMD Millipore HIST1H46L6 antibody (Millipore, 05-858) was used in chromatin immunoprecipitation on human samples . J Biol Chem (2014) ncbi
rabbit polyclonal
  • western blot; mouse; 1:2000
EMD Millipore HIST1H46L6 antibody (Millipore, 07-108) was used in western blot on mouse samples at 1:2000. J Biol Chem (2013) ncbi
rabbit polyclonal
  • western blot; human; fig 5
EMD Millipore HIST1H46L6 antibody (Millipore, 07-108) was used in western blot on human samples (fig 5). PLoS ONE (2013) ncbi
rabbit monoclonal (62-141-13)
  • western blot; human
EMD Millipore HIST1H46L6 antibody (Millipore, 05-858) was used in western blot on human samples . Nucleic Acids Res (2013) ncbi
rabbit monoclonal (62-141-13)
  • western blot; human
EMD Millipore HIST1H46L6 antibody (Millipore, 05-858) was used in western blot on human samples . PLoS ONE (2012) ncbi
rabbit monoclonal (62-141-13)
  • western blot; human
EMD Millipore HIST1H46L6 antibody (Upstate, 05-858) was used in western blot on human samples . Biochem Pharmacol (2011) ncbi
rabbit monoclonal (62-141-13)
  • western blot; fruit fly; 1:1000
  • chromatin immunoprecipitation; Caenorhabditis elegans
EMD Millipore HIST1H46L6 antibody (Millipore, 05-858) was used in western blot on fruit fly samples at 1:1000 and in chromatin immunoprecipitation on Caenorhabditis elegans samples . Nat Struct Mol Biol (2011) ncbi
Articles Reviewed
  1. Warkocki Z, Krawczyk P, Adamska D, Bijata K, Garcia Perez J, Dziembowski A. Uridylation by TUT4/7 Restricts Retrotransposition of Human LINE-1s. Cell. 2018;174:1537-1548.e29 pubmed publisher
  2. Ryu K, Nandu T, Kim J, Challa S, DeBerardinis R, Kraus W. Metabolic regulation of transcription through compartmentalized NAD+ biosynthesis. Science. 2018;360: pubmed publisher
  3. Gocheva V, Naba A, Bhutkar A, Guardia T, Miller K, Li C, et al. Quantitative proteomics identify Tenascin-C as a promoter of lung cancer progression and contributor to a signature prognostic of patient survival. Proc Natl Acad Sci U S A. 2017;114:E5625-E5634 pubmed publisher
  4. Mews P, Donahue G, Drake A, Luczak V, Abel T, Berger S. Acetyl-CoA synthetase regulates histone acetylation and hippocampal memory. Nature. 2017;546:381-386 pubmed publisher
  5. Jia X, Chen J, Megger D, Zhang X, Kozlowski M, Zhang L, et al. Label-free Proteomic Analysis of Exosomes Derived from Inducible Hepatitis B Virus-Replicating HepAD38 Cell Line. Mol Cell Proteomics. 2017;16:S144-S160 pubmed publisher
  6. Liu Y, Wang T, Zhang R, Fu W, Wang X, Wang F, et al. Calorie restriction protects against experimental abdominal aortic aneurysms in mice. J Exp Med. 2016;213:2473-2488 pubmed
  7. Guturi K, Bohgaki M, Bohgaki T, Srikumar T, Ng D, Kumareswaran R, et al. RNF168 and USP10 regulate topoisomerase IIα function via opposing effects on its ubiquitylation. Nat Commun. 2016;7:12638 pubmed publisher
  8. Yang J, Song T, Jo C, Park J, Lee H, Song I, et al. Differential regulation of the histone chaperone HIRA during muscle cell differentiation by a phosphorylation switch. Exp Mol Med. 2016;48:e252 pubmed publisher
  9. You L, Li L, Zou J, Yan K, Belle J, Nijnik A, et al. BRPF1 is essential for development of fetal hematopoietic stem cells. J Clin Invest. 2016;126:3247-62 pubmed publisher
  10. Diamant G, Bahat A, Dikstein R. The elongation factor Spt5 facilitates transcription initiation for rapid induction of inflammatory-response genes. Nat Commun. 2016;7:11547 pubmed publisher
  11. Zheng Q, Liu H, Ye J, Zhang H, Jia Z, Cao J. Nuclear distribution of eIF3g and its interacting nuclear proteins in breast cancer cells. Mol Med Rep. 2016;13:2973-80 pubmed publisher
  12. Hasvold G, Lund Andersen C, Lando M, Patzke S, Hauge S, Suo Z, et al. Hypoxia-induced alterations of G2 checkpoint regulators. Mol Oncol. 2016;10:764-73 pubmed publisher
  13. Seidel C, Schnekenburger M, Mazumder A, Teiten M, Kirsch G, Dicato M, et al. 4-Hydroxybenzoic acid derivatives as HDAC6-specific inhibitors modulating microtubular structure and HSP90α chaperone activity against prostate cancer. Biochem Pharmacol. 2016;99:31-52 pubmed publisher
  14. Ouyang S, Song Y, Tian Y, Chen Y, Yu X, Wang D. RNF8 deficiency results in neurodegeneration in mice. Neurobiol Aging. 2015;36:2850-2860 pubmed publisher
  15. Sarma P, Bag I, Ramaiah M, Kamal A, Bhadra U, Pal Bhadra M. Bisindole-PBD regulates breast cancer cell proliferation via SIRT-p53 axis. Cancer Biol Ther. 2015;16:1486-501 pubmed publisher
  16. Sedic M, Skibinski A, Brown N, Gallardo M, Mulligan P, Martinez P, et al. Haploinsufficiency for BRCA1 leads to cell-type-specific genomic instability and premature senescence. Nat Commun. 2015;6:7505 pubmed publisher
  17. Varshney D, Vavrova Anderson J, Oler A, Cowling V, Cairns B, White R. SINE transcription by RNA polymerase III is suppressed by histone methylation but not by DNA methylation. Nat Commun. 2015;6:6569 pubmed publisher
  18. Nakshatri H, Appaiah H, Anjanappa M, Gilley D, Tanaka H, Badve S, et al. NF-κB-dependent and -independent epigenetic modulation using the novel anti-cancer agent DMAPT. Cell Death Dis. 2015;6:e1608 pubmed publisher
  19. Inaba J, McConnell E, Davis K. Lunasin sensitivity in non-small cell lung cancer cells is linked to suppression of integrin signaling and changes in histone acetylation. Int J Mol Sci. 2014;15:23705-24 pubmed publisher
  20. Pamblanco M, Oliete Calvo P, García Oliver E, Luz Valero M, Sánchez Del Pino M, Rodriguez Navarro S. Unveiling novel interactions of histone chaperone Asf1 linked to TREX-2 factors Sus1 and Thp1. Nucleus. 2014;5:247-59 pubmed publisher
  21. Tafrova J, Tafrov S. Human histone acetyltransferase 1 (Hat1) acetylates lysine 5 of histone H2A in vivo. Mol Cell Biochem. 2014;392:259-72 pubmed publisher
  22. Creamer K, Job G, Shanker S, Neale G, Lin Y, Bartholomew B, et al. The Mi-2 homolog Mit1 actively positions nucleosomes within heterochromatin to suppress transcription. Mol Cell Biol. 2014;34:2046-61 pubmed publisher
  23. Alabert C, Bukowski Wills J, Lee S, Kustatscher G, Nakamura K, de Lima Alves F, et al. Nascent chromatin capture proteomics determines chromatin dynamics during DNA replication and identifies unknown fork components. Nat Cell Biol. 2014;16:281-93 pubmed publisher
  24. Kapoor Vazirani P, Vertino P. A dual role for the histone methyltransferase PR-SET7/SETD8 and histone H4 lysine 20 monomethylation in the local regulation of RNA polymerase II pausing. J Biol Chem. 2014;289:7425-37 pubmed publisher
  25. Rass E, Chandramouly G, Zha S, Alt F, Xie A. Ataxia telangiectasia mutated (ATM) is dispensable for endonuclease I-SceI-induced homologous recombination in mouse embryonic stem cells. J Biol Chem. 2013;288:7086-95 pubmed publisher
  26. Shukla S, Sharma H, Abbas A, MacLennan G, Fu P, Danielpour D, et al. Upregulation of SATB1 is associated with prostate cancer aggressiveness and disease progression. PLoS ONE. 2013;8:e53527 pubmed publisher
  27. Lau P, Cheung P. Elucidating combinatorial histone modifications and crosstalks by coupling histone-modifying enzyme with biotin ligase activity. Nucleic Acids Res. 2013;41:e49 pubmed publisher
  28. Larsson P, Ulfhammer E, Magnusson M, Bergh N, Lunke S, El Osta A, et al. Role of histone acetylation in the stimulatory effect of valproic acid on vascular endothelial tissue-type plasminogen activator expression. PLoS ONE. 2012;7:e31573 pubmed publisher
  29. Karius T, Schnekenburger M, Ghelfi J, Walter J, Dicato M, Diederich M. Reversible epigenetic fingerprint-mediated glutathione-S-transferase P1 gene silencing in human leukemia cell lines. Biochem Pharmacol. 2011;81:1329-42 pubmed publisher
  30. Egelhofer T, Minoda A, Klugman S, Lee K, Kolasinska Zwierz P, Alekseyenko A, et al. An assessment of histone-modification antibody quality. Nat Struct Mol Biol. 2011;18:91-3 pubmed publisher