This is a Validated Antibody Database (VAD) review about chicken BCL2, based on 27 published articles (read how Labome selects the articles), using BCL2 antibody in all methods. It is aimed to help Labome visitors find the most suited BCL2 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
BCL2 synonym: BCL-2; PCKBCL2; apoptosis regulator Bcl-2; B-cell CLL/lymphoma 2

Proteintech Group
rabbit polyclonal
  • western blot; human; loading ...; fig s2
Proteintech Group BCL2 antibody (Proteintech, 12789) was used in western blot on human samples (fig s2). Oncotarget (2017) ncbi
rabbit polyclonal
  • western blot; human; 1:2000; loading ...; fig 4c
Proteintech Group BCL2 antibody (Proteintech, 12789-1-AP) was used in western blot on human samples at 1:2000 (fig 4c). Exp Ther Med (2017) ncbi
rabbit polyclonal
  • western blot; human; loading ...; fig 7a
Proteintech Group BCL2 antibody (Protein Tech Group, 12789-1-AP) was used in western blot on human samples (fig 7a). Int J Mol Sci (2016) ncbi
rabbit polyclonal
  • immunohistochemistry - paraffin section; mouse; 1:50; fig 3
Proteintech Group BCL2 antibody (Proteintech Group, 12789-1-AP) was used in immunohistochemistry - paraffin section on mouse samples at 1:50 (fig 3). Mol Med Rep (2016) ncbi
rabbit polyclonal
  • western blot; mouse; fig 7
Proteintech Group BCL2 antibody (Proteintech, 12789-1-AP) was used in western blot on mouse samples (fig 7). Oncotarget (2016) ncbi
rabbit polyclonal
  • western blot; human; loading ...; fig 6b
Proteintech Group BCL2 antibody (Proteintech, 12789) was used in western blot on human samples (fig 6b). Tumour Biol (2016) ncbi
rabbit polyclonal
  • western blot; rat; 1:500; loading ...; fig 3d
Proteintech Group BCL2 antibody (Proteintech, 12789-1-AP) was used in western blot on rat samples at 1:500 (fig 3d). Int J Endocrinol (2016) ncbi
rabbit polyclonal
  • western blot; human; 1:1000; fig 4
Proteintech Group BCL2 antibody (Proteintech, 12789-1-AP) was used in western blot on human samples at 1:1000 (fig 4). Autophagy (2016) ncbi
rabbit polyclonal
  • western blot; human; 1:1000; fig 5
Proteintech Group BCL2 antibody (Proteintech, 12789-1-AP) was used in western blot on human samples at 1:1000 (fig 5). Mol Med Rep (2016) ncbi
rabbit polyclonal
  • western blot; human; 1:1000; fig 3
In order to study prostate cancer DU145 cells and anti-tumor activity of the TRPM8 inhibitor BCTC, Proteintech Group BCL2 antibody (ProteinTech Group, 12789-1-AP) was used in western blot on human samples at 1:1000 (fig 3). Oncol Lett (2016) ncbi
rabbit polyclonal
  • western blot; human; loading ...; fig 6d
Proteintech Group BCL2 antibody (ProteinTech, 12789-1-AP) was used in western blot on human samples (fig 6d). Oncotarget (2015) ncbi
rabbit polyclonal
  • western blot; human; loading ...; fig 4h
Proteintech Group BCL2 antibody (Proteintech, 12789-1-AP) was used in western blot on human samples (fig 4h). Oncotarget (2015) ncbi
rabbit polyclonal
  • western blot; human; 1:500
Proteintech Group BCL2 antibody (Proteintech, 12789-1-AP) was used in western blot on human samples at 1:500. Mol Carcinog (2016) ncbi
rabbit polyclonal
  • western blot; human; 1:1000; fig  3
Proteintech Group BCL2 antibody (Proteintech, 12789-1-AP) was used in western blot on human samples at 1:1000 (fig  3). PLoS ONE (2014) ncbi
BD Biosciences
mouse monoclonal (7/Bcl-2)
  • western blot; mouse; loading ...; fig 1b
BD Biosciences BCL2 antibody (BD Biosciences, 7) was used in western blot on mouse samples (fig 1b). Cell Death Differ (2017) ncbi
mouse monoclonal (7/Bcl-2)
  • immunohistochemistry - paraffin section; human; fig 6b
BD Biosciences BCL2 antibody (BD Biosciences, 610538) was used in immunohistochemistry - paraffin section on human samples (fig 6b). Oncotarget (2016) ncbi
mouse monoclonal (7/Bcl-2)
  • western blot; human; fig 4a
In order to evaluate the therapeutic use of the dental pulp stem cell secretome to reduce cytotoxicity and apoptosis caused by the amyloid beta peptide, BD Biosciences BCL2 antibody (BD, 610538) was used in western blot on human samples (fig 4a). Stem Cells Int (2016) ncbi
mouse monoclonal (7/Bcl-2)
  • western blot; human; 1:500; fig 6
BD Biosciences BCL2 antibody (BD, 610538) was used in western blot on human samples at 1:500 (fig 6). Cell Rep (2016) ncbi
mouse monoclonal (7/Bcl-2)
  • western blot; human; fig 4
BD Biosciences BCL2 antibody (BD Biosciences, 610539) was used in western blot on human samples (fig 4). Oncotarget (2016) ncbi
mouse monoclonal (7/Bcl-2)
  • western blot; mouse; 1:100; fig 6d, 6e
BD Biosciences BCL2 antibody (BD Transduction Laboratories, 610539) was used in western blot on mouse samples at 1:100 (fig 6d, 6e). FEBS Open Bio (2015) ncbi
mouse monoclonal (7/Bcl-2)
  • western blot; human; 1:1000; fig 3
BD Biosciences BCL2 antibody (BD Biosciences, 610539) was used in western blot on human samples at 1:1000 (fig 3). PLoS ONE (2015) ncbi
mouse monoclonal (7/Bcl-2)
  • western blot; human; loading ...; fig 5a,5c
BD Biosciences BCL2 antibody (BD Biosciences, 610538) was used in western blot on human samples (fig 5a,5c). Cell Death Dis (2015) ncbi
mouse monoclonal (7/Bcl-2)
  • western blot; human; fig 5
BD Biosciences BCL2 antibody (BD Biosciences, 610538) was used in western blot on human samples (fig 5). Biomed Res Int (2015) ncbi
mouse monoclonal (7/Bcl-2)
  • immunoprecipitation; human
BD Biosciences BCL2 antibody (BD Transduction Laboratories, 7/Bcl-2) was used in immunoprecipitation on human samples . Biochem Biophys Res Commun (2014) ncbi
mouse monoclonal (7/Bcl-2)
  • western blot; human
BD Biosciences BCL2 antibody (BD Transduction Laboratories, 610539) was used in western blot on human samples . Mol Cell Biol (2014) ncbi
mouse monoclonal (7/Bcl-2)
  • western blot; human
In order to investigate the effect of antimesothelin immunotoxin SS1P and BH3-mimetic ABT-737 on SS1P-resistant pancreatic cancer cells, BD Biosciences BCL2 antibody (BD Transduction Laboratories, 610539) was used in western blot on human samples . J Immunother (2014) ncbi
mouse monoclonal (7/Bcl-2)
  • western blot; human; 1:500
BD Biosciences BCL2 antibody (BD Transduction Laboratories, 610538) was used in western blot on human samples at 1:500. PLoS ONE (2013) ncbi
Articles Reviewed
  1. Shuang W, Hou L, Zhu Y, Li Q, Hu W. Mcl-1 stabilization confers resistance to taxol in human gastric cancer. Oncotarget. 2017;8:82981-82990 pubmed publisher
  2. Xu X, Cui Y, Cao L, Zhang Y, Yin Y, Hu X. PCSK9 regulates apoptosis in human lung adenocarcinoma A549 cells via endoplasmic reticulum stress and mitochondrial signaling pathways. Exp Ther Med. 2017;13:1993-1999 pubmed publisher
  3. Schenk R, Tuzlak S, Carrington E, Zhan Y, Heinzel S, Teh C, et al. Characterisation of mice lacking all functional isoforms of the pro-survival BCL-2 family member A1 reveals minor defects in the haematopoietic compartment. Cell Death Differ. 2017;24:534-545 pubmed publisher
  4. Zhang W, Kang M, Zhang T, Li B, Liao X, Wang R. Triptolide Combined with Radiotherapy for the Treatment of Nasopharyngeal Carcinoma via NF-?B-Related Mechanism. Int J Mol Sci. 2016;17: pubmed publisher
  5. Torres A, Vargas Y, Uribe D, Jaramillo C, Gleisner A, Salazar Onfray F, et al. Adenosine A3 receptor elicits chemoresistance mediated by multiple resistance-associated protein-1 in human glioblastoma stem-like cells. Oncotarget. 2016;7:67373-67386 pubmed publisher
  6. Ren X, Liu H, Zhang M, Wang M, Ma S. Co-expression of ING4 and P53 enhances hypopharyngeal cancer chemosensitivity to cisplatin in vivo. Mol Med Rep. 2016;14:2431-8 pubmed publisher
  7. Pang J, Wu Y, Peng J, Yang P, Kuai L, Qin X, et al. Potential implications of Apolipoprotein E in early brain injury after experimental subarachnoid hemorrhage: Involvement in the modulation of blood-brain barrier integrity. Oncotarget. 2016;7:56030-56044 pubmed publisher
  8. Zhao Y, Zhang B, Lei Y, Sun J, Zhang Y, Yang S, et al. Knockdown of USP39 induces cell cycle arrest and apoptosis in melanoma. Tumour Biol. 2016;37:13167-13176 pubmed
  9. Ahmed N, Murakami M, Hirose Y, Nakashima M. Therapeutic Potential of Dental Pulp Stem Cell Secretome for Alzheimer's Disease Treatment: An In Vitro Study. Stem Cells Int. 2016;2016:8102478 pubmed publisher
  10. Zhang C, Li L, Zhao B, Jiao A, Li X, Sun N, et al. Ghrelin Protects against Dexamethasone-Induced INS-1 Cell Apoptosis via ERK and p38MAPK Signaling. Int J Endocrinol. 2016;2016:4513051 pubmed publisher
  11. Huang Q, Zhan L, Cao H, Li J, Lyu Y, Guo X, et al. Increased mitochondrial fission promotes autophagy and hepatocellular carcinoma cell survival through the ROS-modulated coordinated regulation of the NFKB and TP53 pathways. Autophagy. 2016;12:999-1014 pubmed publisher
  12. Conway A, Van Nostrand E, Pratt G, Aigner S, Wilbert M, Sundararaman B, et al. Enhanced CLIP Uncovers IMP Protein-RNA Targets in Human Pluripotent Stem Cells Important for Cell Adhesion and Survival. Cell Rep. 2016;15:666-679 pubmed publisher
  13. Jing H, Sun W, Fan J, Zhang Y, Yang J, Jia J, et al. Shikonin induces apoptosis of HaCaT cells via the mitochondrial, Erk and Akt pathways. Mol Med Rep. 2016;13:3009-16 pubmed publisher
  14. Liu T, Fang Z, Wang G, Shi M, Wang X, Jiang K, et al. Anti-tumor activity of the TRPM8 inhibitor BCTC in prostate cancer DU145 cells. Oncol Lett. 2016;11:182-188 pubmed
  15. De Toni E, Ziesch A, Rizzani A, Török H, Hocke S, Lü S, et al. Inactivation of BRCA2 in human cancer cells identifies a subset of tumors with enhanced sensitivity towards death receptor-mediated apoptosis. Oncotarget. 2016;7:9477-90 pubmed publisher
  16. Ci X, Li B, Ma X, Kong F, Zheng C, Björkholm M, et al. Bortezomib-mediated down-regulation of telomerase and disruption of telomere homeostasis contributes to apoptosis of malignant cells. Oncotarget. 2015;6:38079-92 pubmed publisher
  17. Anderson K, Russell A, Foletta V. NDRG2 promotes myoblast proliferation and caspase 3/7 activities during differentiation, and attenuates hydrogen peroxide - But not palmitate-induced toxicity. FEBS Open Bio. 2015;5:668-81 pubmed publisher
  18. Lorkova L, Scigelova M, Arrey T, Vit O, Pospisilova J, Doktorova E, et al. Detailed Functional and Proteomic Characterization of Fludarabine Resistance in Mantle Cell Lymphoma Cells. PLoS ONE. 2015;10:e0135314 pubmed publisher
  19. Dai W, Wang F, Lu J, Xia Y, He L, Chen K, et al. By reducing hexokinase 2, resveratrol induces apoptosis in HCC cells addicted to aerobic glycolysis and inhibits tumor growth in mice. Oncotarget. 2015;6:13703-17 pubmed
  20. Farrugia M, Sharma S, Lin C, McLaughlin S, Vanderbilt D, Ammer A, et al. Regulation of anti-apoptotic signaling by Kruppel-like factors 4 and 5 mediates lapatinib resistance in breast cancer. Cell Death Dis. 2015;6:e1699 pubmed publisher
  21. Huang P, Hung S, Pao C, Wang T. N-(1-pyrenyl) maleimide induces bak oligomerization and mitochondrial dysfunction in Jurkat Cells. Biomed Res Int. 2015;2015:798489 pubmed publisher
  22. Zhang X, Pan Q, Pan K, Weng D, Wang Q, Zhao J, et al. Expression and prognostic role of ubiquitination factor E4B in primary hepatocellular carcinoma. Mol Carcinog. 2016;55:64-76 pubmed publisher
  23. Morita A, Ariyasu S, Wang B, Asanuma T, Onoda T, Sawa A, et al. AS-2, a novel inhibitor of p53-dependent apoptosis, prevents apoptotic mitochondrial dysfunction in a transcription-independent manner and protects mice from a lethal dose of ionizing radiation. Biochem Biophys Res Commun. 2014;450:1498-504 pubmed publisher
  24. Cen B, Xiong Y, Song J, Mahajan S, DuPont R, McEachern K, et al. The Pim-1 protein kinase is an important regulator of MET receptor tyrosine kinase levels and signaling. Mol Cell Biol. 2014;34:2517-32 pubmed publisher
  25. Sun S, Han Y, Liu J, Fang Y, Tian Y, Zhou J, et al. Trichostatin A targets the mitochondrial respiratory chain, increasing mitochondrial reactive oxygen species production to trigger apoptosis in human breast cancer cells. PLoS ONE. 2014;9:e91610 pubmed publisher
  26. Hollevoet K, Antignani A, FitzGerald D, Pastan I. Combining the antimesothelin immunotoxin SS1P with the BH3-mimetic ABT-737 induces cell death in SS1P-resistant pancreatic cancer cells. J Immunother. 2014;37:8-15 pubmed publisher
  27. Thompson R, Vardinogiannis I, Gilmore T. The sensitivity of diffuse large B-cell lymphoma cell lines to histone deacetylase inhibitor-induced apoptosis is modulated by BCL-2 family protein activity. PLoS ONE. 2013;8:e62822 pubmed publisher