This is a Validated Antibody Database (VAD) review about bovine SYN1, based on 26 published articles (read how Labome selects the articles), using SYN1 antibody in all methods. It is aimed to help Labome visitors find the most suited SYN1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Invitrogen
domestic rabbit polyclonal
  • immunohistochemistry; mouse; 1:200; loading ...; fig 4c
In order to characterize PSD95 postsynaptic supercomplexes, Invitrogen SYN1 antibody (Thermofisher, OPA1-04001) was used in immunohistochemistry on mouse samples at 1:200 (fig 4c). J Neurochem (2017) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - free floating section; mouse; loading ...; fig s5a
  • western blot; mouse; loading ...; fig 5h
In order to use a mitochondrial single-channel patch clamp and cyclophilin D-deficient mice with streptozotocin-induced diabetes to study mitochondrial dysfunction, Invitrogen SYN1 antibody (Affinity Bioreagents, PA1-4673) was used in immunohistochemistry - free floating section on mouse samples (fig s5a) and in western blot on mouse samples (fig 5h). Diabetes (2016) ncbi
domestic rabbit polyclonal
  • immunocytochemistry; human; 1:50; fig 5b
In order to test if glucocerebrosidase activation reduces alpha-synuclein levels, Invitrogen SYN1 antibody (Thermo Fisher Scientific, A6442) was used in immunocytochemistry on human samples at 1:50 (fig 5b). J Neurosci (2016) ncbi
domestic rabbit polyclonal
  • immunocytochemistry; human; 1:200; fig 4
  • immunohistochemistry; rat; 1:200; fig 4
In order to investigate human induced pluripotent stem cell-derived neurons in vitro and their innervation of cochlear hair cells, Invitrogen SYN1 antibody (Life Technologies, A6442) was used in immunocytochemistry on human samples at 1:200 (fig 4) and in immunohistochemistry on rat samples at 1:200 (fig 4). Stem Cells Int (2016) ncbi
domestic rabbit polyclonal
  • immunocytochemistry; rat; 1:1000; fig 1
In order to study presynaptic terminals and biophyscial constraints of optogeneitc inhibition, Invitrogen SYN1 antibody (Invitrogen, 51-5200) was used in immunocytochemistry on rat samples at 1:1000 (fig 1). Nat Neurosci (2016) ncbi
domestic rabbit polyclonal
  • western blot; human
In order to investigate how glimepiride protects neurons against synapse damage induced by Abeta, Invitrogen SYN1 antibody (Invitrogen, 515200) was used in western blot on human samples . Neuropharmacology (2016) ncbi
domestic rabbit polyclonal
In order to identify the transcription factors that determine the rostocaudal and dorsoventral identity of NT2N derived from a monolayer differentiation model, Invitrogen SYN1 antibody (Invitrogen, A6442) was used . PLoS ONE (2011) ncbi
Synaptic Systems
guinea-pigs polyclonal (/)
  • immunocytochemistry; rat; 1:500; loading ...; fig 3c
Synaptic Systems SYN1 antibody (Synaptic Systems, 106004) was used in immunocytochemistry on rat samples at 1:500 (fig 3c). elife (2019) ncbi
Abcam
domestic rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig s1b
Abcam SYN1 antibody (Abcam, ab8) was used in western blot on human samples at 1:1000 (fig s1b). Science (2018) ncbi
EMD Millipore
mouse monoclonal (10.22)
  • western blot; mouse; 1:1000; loading ...; fig s6e
EMD Millipore SYN1 antibody (Millipore, MABN894) was used in western blot on mouse samples at 1:1000 (fig s6e). Sci Adv (2019) ncbi
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig 5b
EMD Millipore SYN1 antibody (Millipore, AB1543P) was used in western blot on mouse samples (fig 5b). Cell Rep (2018) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - frozen section; mouse; fig 3u
EMD Millipore SYN1 antibody (Millipore, AB1543P) was used in immunohistochemistry - frozen section on mouse samples (fig 3u). Cell (2018) ncbi
domestic rabbit polyclonal
  • immunohistochemistry; mouse; 1:500; loading ...; fig s8d
EMD Millipore SYN1 antibody (EMD Millipore, AB1543P) was used in immunohistochemistry on mouse samples at 1:500 (fig s8d). Science (2018) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:2000; loading ...; fig 4c
EMD Millipore SYN1 antibody (Millipore, AB1543P) was used in western blot on mouse samples at 1:2000 (fig 4c). Nat Commun (2017) ncbi
domestic rabbit polyclonal
  • other; rat; loading ...; fig 5c
EMD Millipore SYN1 antibody (EMD Millipore, AB1543) was used in other on rat samples (fig 5c). J Cell Biol (2017) ncbi
domestic rabbit polyclonal
  • western blot; rat; loading ...; fig 5a
EMD Millipore SYN1 antibody (Millipore, AB1543P) was used in western blot on rat samples (fig 5a). Front Cell Neurosci (2017) ncbi
domestic rabbit polyclonal
  • immunocytochemistry; rat; 1:500; loading ...; fig 2b
In order to find that synaptic cell adhesion molecules 1-3 are functionally redundant and collectively necessary for synapse formation in cultured hippocampal neurons, EMD Millipore SYN1 antibody (Millipore, AB1543) was used in immunocytochemistry on rat samples at 1:500 (fig 2b). Front Mol Neurosci (2017) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:500; loading ...; fig 3a
In order to test if bone loss is a component of an Alzheimer's disease prodrome, EMD Millipore SYN1 antibody (Millipore, AB1543P) was used in western blot on mouse samples at 1:500 (fig 3a). J Alzheimers Dis (2017) ncbi
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig 7a
In order to examine the dopaminergic abnormalities in Histone deacetylase 6 knockout mice, EMD Millipore SYN1 antibody (Millipore, AB1543P) was used in western blot on mouse samples (fig 7a). Neuropharmacology (2016) ncbi
domestic rabbit polyclonal
  • immunocytochemistry; human; 1:500; loading ...; fig 1h
EMD Millipore SYN1 antibody (EMD-Millipore, AB1543P) was used in immunocytochemistry on human samples at 1:500 (fig 1h). Nature (2016) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - frozen section; mouse; 1:200; fig s3
In order to characterize the drive of synapse loss during virus-induced memory impairment by a complement-microglial axis, EMD Millipore SYN1 antibody (Millipore, Ab1543) was used in immunohistochemistry - frozen section on mouse samples at 1:200 (fig s3). Nature (2016) ncbi
domestic rabbit polyclonal
  • immunocytochemistry; human; 1:500; fig 8
EMD Millipore SYN1 antibody (Merck Millipore, AB1543) was used in immunocytochemistry on human samples at 1:500 (fig 8). PLoS ONE (2016) ncbi
domestic rabbit polyclonal
  • immunocytochemistry; human; fig 2
EMD Millipore SYN1 antibody (Millipore, AB1543) was used in immunocytochemistry on human samples (fig 2). Sci Rep (2016) ncbi
domestic rabbit polyclonal
  • western blot; mouse; fig 2
In order to characterize regulation of expression of synaptic vesicle proteins in excitatory neurons by non-canonical Notch signaling, EMD Millipore SYN1 antibody (Chemicon, AB1543) was used in western blot on mouse samples (fig 2). Sci Rep (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; fig 5
EMD Millipore SYN1 antibody (Merck KGaA, AB1543P) was used in western blot on human samples (fig 5). Acta Neuropathol Commun (2016) ncbi
domestic rabbit polyclonal
EMD Millipore SYN1 antibody (Millipore, ab1543) was used . J Neurosci (2014) ncbi
Articles Reviewed
  1. Wegmann S, Bennett R, Delorme L, Robbins A, Hu M, McKenzie D, et al. Experimental evidence for the age dependence of tau protein spread in the brain. Sci Adv. 2019;5:eaaw6404 pubmed publisher
  2. Rademacher N, Kuropka B, Kunde S, Wahl M, Freund C, Shoichet S. Intramolecular domain dynamics regulate synaptic MAGUK protein interactions. elife. 2019;8: pubmed publisher
  3. Schaffer T, Smith J, Cook E, Phan T, Margolis S. PKCε Inhibits Neuronal Dendritic Spine Development through Dual Phosphorylation of Ephexin5. Cell Rep. 2018;25:2470-2483.e8 pubmed publisher
  4. Real R, Peter M, Trabalza A, Khan S, Smith M, Dopp J, et al. In vivo modeling of human neuron dynamics and Down syndrome. Science. 2018;362: pubmed publisher
  5. Dias D, Kim H, Holl D, Werne Solnestam B, Lundeberg J, Carlen M, et al. Reducing Pericyte-Derived Scarring Promotes Recovery after Spinal Cord Injury. Cell. 2018;173:153-165.e22 pubmed publisher
  6. Vainchtein I, Chin G, Cho F, Kelley K, Miller J, Chien E, et al. Astrocyte-derived interleukin-33 promotes microglial synapse engulfment and neural circuit development. Science. 2018;359:1269-1273 pubmed publisher
  7. Tanabe Y, Naito Y, Vasuta C, Lee A, Soumounou Y, Linhoff M, et al. IgSF21 promotes differentiation of inhibitory synapses via binding to neurexin2?. Nat Commun. 2017;8:408 pubmed publisher
  8. Ganguly A, Han X, Das U, Wang L, Loi J, Sun J, et al. Hsc70 chaperone activity is required for the cytosolic slow axonal transport of synapsin. J Cell Biol. 2017;216:2059-2074 pubmed publisher
  9. Frank R, Zhu F, Komiyama N, Grant S. Hierarchical organization and genetically separable subfamilies of PSD95 postsynaptic supercomplexes. J Neurochem. 2017;142:504-511 pubmed publisher
  10. Latina V, Caioli S, Zona C, Ciotti M, Amadoro G, Calissano P. Impaired NGF/TrkA Signaling Causes Early AD-Linked Presynaptic Dysfunction in Cholinergic Primary Neurons. Front Cell Neurosci. 2017;11:68 pubmed publisher
  11. Fowler D, Peters J, Williams C, Washbourne P. Redundant Postsynaptic Functions of SynCAMs 1-3 during Synapse Formation. Front Mol Neurosci. 2017;10:24 pubmed publisher
  12. Dengler Crish C, Smith M, Wilson G. Early Evidence of Low Bone Density and Decreased Serotonergic Synthesis in the Dorsal Raphe of a Tauopathy Model of Alzheimer's Disease. J Alzheimers Dis. 2017;55:1605-1619 pubmed publisher
  13. Yan S, Du F, Wu L, Zhang Z, Zhong C, Yu Q, et al. F1F0 ATP Synthase-Cyclophilin D Interaction Contributes to Diabetes-Induced Synaptic Dysfunction and Cognitive Decline. Diabetes. 2016;65:3482-3494 pubmed
  14. Fukada M, Nakayama A, Mamiya T, Yao T, Kawaguchi Y. Dopaminergic abnormalities in Hdac6-deficient mice. Neuropharmacology. 2016;110:470-479 pubmed publisher
  15. Chailangkarn T, Trujillo C, Freitas B, Hrvoj Mihic B, Herai R, Yu D, et al. A human neurodevelopmental model for Williams syndrome. Nature. 2016;536:338-43 pubmed
  16. Mazzulli J, Zunke F, Tsunemi T, Toker N, Jeon S, Burbulla L, et al. Activation of β-Glucocerebrosidase Reduces Pathological α-Synuclein and Restores Lysosomal Function in Parkinson's Patient Midbrain Neurons. J Neurosci. 2016;36:7693-706 pubmed publisher
  17. Vasek M, Garber C, Dorsey D, Durrant D, Bollman B, Soung A, et al. A complement-microglial axis drives synapse loss during virus-induced memory impairment. Nature. 2016;534:538-43 pubmed publisher
  18. Rosiak K, Smolarz M, Stec W, Peciak J, Grzela D, Winiecka Klimek M, et al. IDH1R132H in Neural Stem Cells: Differentiation Impaired by Increased Apoptosis. PLoS ONE. 2016;11:e0154726 pubmed publisher
  19. Kim E, Jeon C, Lee S, Hwang I, Chung T. Robust Type-specific Hemisynapses Induced by Artificial Dendrites. Sci Rep. 2016;6:24210 pubmed publisher
  20. Hayashi Y, Nishimune H, Hozumi K, Saga Y, Harada A, Yuzaki M, et al. A novel non-canonical Notch signaling regulates expression of synaptic vesicle proteins in excitatory neurons. Sci Rep. 2016;6:23969 pubmed publisher
  21. Kurbatskaya K, Phillips E, Croft C, Dentoni G, Hughes M, Wade M, et al. Upregulation of calpain activity precedes tau phosphorylation and loss of synaptic proteins in Alzheimer's disease brain. Acta Neuropathol Commun. 2016;4:34 pubmed publisher
  22. Gunewardene N, Crombie D, Dottori M, Nayagam B. Innervation of Cochlear Hair Cells by Human Induced Pluripotent Stem Cell-Derived Neurons In Vitro. Stem Cells Int. 2016;2016:1781202 pubmed publisher
  23. Mahn M, Prigge M, Ron S, Levy R, Yizhar O. Biophysical constraints of optogenetic inhibition at presynaptic terminals. Nat Neurosci. 2016;19:554-6 pubmed publisher
  24. Osborne C, West E, Nolan W, McHale Owen H, Williams A, Bate C. Glimepiride protects neurons against amyloid-β-induced synapse damage. Neuropharmacology. 2016;101:225-36 pubmed publisher
  25. Leinders Zufall T, Ishii T, Chamero P, Hendrix P, Oboti L, Schmid A, et al. A family of nonclassical class I MHC genes contributes to ultrasensitive chemodetection by mouse vomeronasal sensory neurons. J Neurosci. 2014;34:5121-33 pubmed publisher
  26. Coyle D, Li J, Baccei M. Regional differentiation of retinoic acid-induced human pluripotent embryonic carcinoma stem cell neurons. PLoS ONE. 2011;6:e16174 pubmed publisher