This is a Validated Antibody Database (VAD) review about bovine STK4, based on 26 published articles (read how Labome selects the articles), using STK4 antibody in all methods. It is aimed to help Labome visitors find the most suited STK4 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Knockout validation
Cell Signaling Technology
domestic rabbit polyclonal
  • western blot knockout validation; human; loading ...; fig 1f
Cell Signaling Technology STK4 antibody (Cell Signaling, 3682) was used in western blot knockout validation on human samples (fig 1f). elife (2020) ncbi
Cell Signaling Technology
domestic rabbit polyclonal
  • western blot knockout validation; human; loading ...; fig 4b
Cell Signaling Technology STK4 antibody (Cell Signaling, 3682) was used in western blot knockout validation on human samples (fig 4b). J Biol Chem (2016) ncbi
Cell Signaling Technology
domestic rabbit polyclonal
  • western blot; human; loading ...
Cell Signaling Technology STK4 antibody (Cell Signaling Technology, 3682) was used in western blot on human samples . Cell Death Dis (2021) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 4e
Cell Signaling Technology STK4 antibody (Cell Signal, 3682) was used in western blot on human samples (fig 4e). Clin Transl Med (2021) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:1000; loading ...; fig s1b, s3a
Cell Signaling Technology STK4 antibody (CST, 3682) was used in western blot on mouse samples at 1:1000 (fig s1b, s3a). Aging Cell (2021) ncbi
domestic rabbit polyclonal
  • western blot; rat; loading ...; fig 2l
Cell Signaling Technology STK4 antibody (CST, 3682) was used in western blot on rat samples (fig 2l). Cell Rep (2021) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:3000; loading ...; fig 4h
Cell Signaling Technology STK4 antibody (Cell Signaling, 3682) was used in western blot on human samples at 1:3000 (fig 4h). Nat Commun (2021) ncbi
domestic rabbit polyclonal
  • western blot knockout validation; human; loading ...; fig 1f
Cell Signaling Technology STK4 antibody (Cell Signaling, 3682) was used in western blot knockout validation on human samples (fig 1f). elife (2020) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:1000; loading ...; fig 1
Cell Signaling Technology STK4 antibody (Cell Signaling Technology,, #3682) was used in western blot on mouse samples at 1:1000 (fig 1). Aging (Albany NY) (2020) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig 3d
Cell Signaling Technology STK4 antibody (Cell signalling, 3682) was used in western blot on human samples at 1:1000 (fig 3d). EBioMedicine (2019) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:1000; fig 1c
Cell Signaling Technology STK4 antibody (Cell Signaling, 3682) was used in western blot on human samples at 1:1000 (fig 1c). Stem Cells (2019) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig 3a
Cell Signaling Technology STK4 antibody (Cell Signaling Technology, 3682) was used in western blot on human samples at 1:1000 (fig 3a). Cancer Manag Res (2019) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:1000; loading ...; fig 1b
Cell Signaling Technology STK4 antibody (Cell Signalling Technology, 3682) was used in western blot on mouse samples at 1:1000 (fig 1b). Redox Biol (2019) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:500; fig 3b
Cell Signaling Technology STK4 antibody (Cell Signaling, 3682S) was used in western blot on human samples at 1:500 (fig 3b). Oncotarget (2017) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 2c
Cell Signaling Technology STK4 antibody (Cell Signaling, 3682) was used in western blot on human samples (fig 2c). Cancer Res (2017) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:1000; loading ...; fig s3I
In order to find that that Fat4 modulates Hippo signaling and restricts hearth growth in mice, Cell Signaling Technology STK4 antibody (Cell signalling, 3682) was used in western blot on mouse samples at 1:1000 (fig s3I). Nat Commun (2017) ncbi
domestic rabbit polyclonal
  • immunoprecipitation; human; loading ...; fig 5d
Cell Signaling Technology STK4 antibody (Cell Signaling, 3682) was used in immunoprecipitation on human samples (fig 5d). EMBO Rep (2017) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:1000; loading ...; fig 6e
In order to find that CD4+ T cells from DOCK8-deficient mice produce large amounts of IL-31, Cell Signaling Technology STK4 antibody (Cell Signaling, 3682) was used in western blot on mouse samples at 1:1000 (fig 6e). Nat Commun (2017) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 4
Cell Signaling Technology STK4 antibody (Cell Signaling, 3682) was used in western blot on human samples (fig 4). Mol Clin Oncol (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig s2f
In order to demonstrate that the Hippo, Wnt/beta-catenin, and Notch pathways interact to regulate liver size and inhibit hepatocellular carcinoma, Cell Signaling Technology STK4 antibody (Cell Signaling, 3682) was used in western blot on human samples (fig s2f). J Clin Invest (2017) ncbi
domestic rabbit polyclonal
  • immunoprecipitation; human; fig 5
  • western blot; human; fig 4
  • immunoprecipitation; mouse; fig 5
  • western blot; mouse; fig 4
Cell Signaling Technology STK4 antibody (Cell Signaling, 3682) was used in immunoprecipitation on human samples (fig 5), in western blot on human samples (fig 4), in immunoprecipitation on mouse samples (fig 5) and in western blot on mouse samples (fig 4). Sci Rep (2016) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:2000; fig s3
In order to investigate the roles of NF2, LATS1/2, and YAP in the branching morphogenesis of the mouse kidney, Cell Signaling Technology STK4 antibody (Cell Signaling, 3682) was used in western blot on mouse samples at 1:2000 (fig s3). Nat Commun (2016) ncbi
domestic rabbit polyclonal
  • western blot knockout validation; human; loading ...; fig 4b
Cell Signaling Technology STK4 antibody (Cell Signaling, 3682) was used in western blot knockout validation on human samples (fig 4b). J Biol Chem (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; fig 5
Cell Signaling Technology STK4 antibody (Cell Signaling Technology, 3682) was used in western blot on human samples (fig 5). Chin J Cancer (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; fig 4
Cell Signaling Technology STK4 antibody (Cell Signaling, 3682) was used in western blot on human samples (fig 4). Cell Signal (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; fig 5
Cell Signaling Technology STK4 antibody (Cell Signaling, 3682) was used in western blot on human samples (fig 5). Oncotarget (2016) ncbi
domestic rabbit polyclonal
  • western blot; mouse; fig 4
Cell Signaling Technology STK4 antibody (Cell Signaling, 3682) was used in western blot on mouse samples (fig 4). Proc Natl Acad Sci U S A (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; fig s2
In order to study the activation mechanisms of core Hippo pathway components, Cell Signaling Technology STK4 antibody (Cell Signaling Technology, 3682) was used in western blot on human samples (fig s2). EMBO Rep (2016) ncbi
Articles Reviewed
  1. Zhang S, Liang S, Wu D, Guo H, Ma K, Liu L. LncRNA coordinates Hippo and mTORC1 pathway activation in cancer. Cell Death Dis. 2021;12:822 pubmed publisher
  2. Zhang Y, He L, Huang L, Yao S, Lin N, Li P, et al. Oncogenic PAX6 elicits CDK4/6 inhibitor resistance by epigenetically inactivating the LATS2-Hippo signaling pathway. Clin Transl Med. 2021;11:e503 pubmed publisher
  3. Xu X, Shen X, Wang J, Feng W, Wang M, Miao X, et al. YAP prevents premature senescence of astrocytes and cognitive decline of Alzheimer's disease through regulating CDK6 signaling. Aging Cell. 2021;20:e13465 pubmed publisher
  4. Lupse B, Annamalai K, Ibrahim H, Kaur S, Geravandi S, Sarma B, et al. Inhibition of PHLPP1/2 phosphatases rescues pancreatic β-cells in diabetes. Cell Rep. 2021;36:109490 pubmed publisher
  5. Dai M, Yan G, Wang N, Daliah G, Edick A, Poulet S, et al. In vivo genome-wide CRISPR screen reveals breast cancer vulnerabilities and synergistic mTOR/Hippo targeted combination therapy. Nat Commun. 2021;12:3055 pubmed publisher
  6. Bae S, Ni L, Luo X. STK25 suppresses Hippo signaling by regulating SAV1-STRIPAK antagonism. elife. 2020;9: pubmed publisher
  7. Shang X, Zhang Y, Xu J, Li M, Wang X, Yu R. SRV2 promotes mitochondrial fission and Mst1-Drp1 signaling in LPS-induced septic cardiomyopathy. Aging (Albany NY). 2020;12:1417-1432 pubmed publisher
  8. Yu M, Cui R, Huang Y, Luo Y, Qin S, Zhong M. Increased proton-sensing receptor GPR4 signalling promotes colorectal cancer progression by activating the hippo pathway. EBioMedicine. 2019;48:264-276 pubmed publisher
  9. Menon V, Thomas R, Elgueta C, Horl M, Osborn T, Hallett P, et al. Comprehensive Cell Surface Antigen Analysis Identifies Transferrin Receptor Protein-1 (CD71) as a Negative Selection Marker for Human Neuronal Cells. Stem Cells. 2019;37:1293-1306 pubmed publisher
  10. Rong X, Han Q, Lin X, Kremerskothen J, Wang E. FRMPD1 activates the Hippo pathway via interaction with WWC3 to suppress the proliferation and invasiveness of lung cancer cells. Cancer Manag Res. 2019;11:3395-3410 pubmed publisher
  11. Li H, Feng J, Zhang Y, Feng J, Wang Q, Zhao S, et al. Mst1 deletion attenuates renal ischaemia-reperfusion injury: The role of microtubule cytoskeleton dynamics, mitochondrial fission and the GSK3β-p53 signalling pathway. Redox Biol. 2019;20:261-274 pubmed publisher
  12. Zheng X, Dong Q, Zhang X, Han Q, Han X, Han Y, et al. The coiled-coil domain of oncogene RASSF 7 inhibits hippo signaling and promotes non-small cell lung cancer. Oncotarget. 2017;8:78734-78748 pubmed publisher
  13. Toloczko A, Guo F, Yuen H, Wen Q, Wood S, Ong Y, et al. Deubiquitinating Enzyme USP9X Suppresses Tumor Growth via LATS Kinase and Core Components of the Hippo Pathway. Cancer Res. 2017;77:4921-4933 pubmed publisher
  14. Ragni C, Diguet N, Le Garrec J, Novotova M, Resende T, Pop S, et al. Amotl1 mediates sequestration of the Hippo effector Yap1 downstream of Fat4 to restrict heart growth. Nat Commun. 2017;8:14582 pubmed publisher
  15. Heidary Arash E, Shiban A, Song S, Attisano L. MARK4 inhibits Hippo signaling to promote proliferation and migration of breast cancer cells. EMBO Rep. 2017;18:420-436 pubmed publisher
  16. Yamamura K, Uruno T, Shiraishi A, Tanaka Y, Ushijima M, Nakahara T, et al. The transcription factor EPAS1 links DOCK8 deficiency to atopic skin inflammation via IL-31 induction. Nat Commun. 2017;8:13946 pubmed publisher
  17. Galoian K, Luo S, Qureshi A, Patel P, Price R, Morse A, et al. Effect of cytostatic proline rich polypeptide-1 on tumor suppressors of inflammation pathway signaling in chondrosarcoma. Mol Clin Oncol. 2016;5:618-624 pubmed
  18. Kim W, Khan S, Gvozdenovic Jeremic J, Kim Y, Dahlman J, Kim H, et al. Hippo signaling interactions with Wnt/?-catenin and Notch signaling repress liver tumorigenesis. J Clin Invest. 2017;127:137-152 pubmed publisher
  19. Vahid S, Thaper D, Gibson K, Bishop J, Zoubeidi A. Molecular chaperone Hsp27 regulates the Hippo tumor suppressor pathway in cancer. Sci Rep. 2016;6:31842 pubmed publisher
  20. Reginensi A, Enderle L, Gregorieff A, Johnson R, Wrana J, McNeill H. A critical role for NF2 and the Hippo pathway in branching morphogenesis. Nat Commun. 2016;7:12309 pubmed publisher
  21. Feng X, Liu P, Zhou X, Li M, Li F, Wang Z, et al. Thromboxane A2 Activates YAP/TAZ Protein to Induce Vascular Smooth Muscle Cell Proliferation and Migration. J Biol Chem. 2016;291:18947-58 pubmed publisher
  22. Wang D, Wu Y, Huang J, Wang W, Xu M, Jia J, et al. Hippo/YAP signaling pathway is involved in osteosarcoma chemoresistance. Chin J Cancer. 2016;35:47 pubmed publisher
  23. Hoa L, Kulaberoglu Y, Gundogdu R, Cook D, Mavis M, Gomez M, et al. The characterisation of LATS2 kinase regulation in Hippo-YAP signalling. Cell Signal. 2016;28:488-497 pubmed publisher
  24. Dai X, Zhuang L, Wang D, Zhou T, Chang L, Gai R, et al. Nuclear translocation and activation of YAP by hypoxia contributes to the chemoresistance of SN38 in hepatocellular carcinoma cells. Oncotarget. 2016;7:6933-47 pubmed publisher
  25. Nishio M, Sugimachi K, Goto H, Wang J, Morikawa T, Miyachi Y, et al. Dysregulated YAP1/TAZ and TGF-β signaling mediate hepatocarcinogenesis in Mob1a/1b-deficient mice. Proc Natl Acad Sci U S A. 2016;113:E71-80 pubmed publisher
  26. Kim M, Kim M, Park S, Lee C, Lim D. Role of Angiomotin-like 2 mono-ubiquitination on YAP inhibition. EMBO Rep. 2016;17:64-78 pubmed publisher