This is a Validated Antibody Database (VAD) review about bovine SDHB, based on 35 published articles (read how Labome selects the articles), using SDHB antibody in all methods. It is aimed to help Labome visitors find the most suited SDHB antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Knockout validation
Abcam
mouse monoclonal (21A11AE7)
  • western blot knockout validation; human; fig 2b
Abcam SDHB antibody (Abcam, ab14714) was used in western blot knockout validation on human samples (fig 2b). Front Endocrinol (Lausanne) (2021) ncbi
Abcam
mouse monoclonal (21A11AE7)
  • western blot knockout validation; human; loading ...; fig 1a
Abcam SDHB antibody (Abcam, ab14714) was used in western blot knockout validation on human samples (fig 1a). Oncotarget (2017) ncbi
Abcam
mouse monoclonal (21A11AE7)
  • western blot; human; 1:1000; loading ...; fig 4a
Abcam SDHB antibody (Abcam, ab14714) was used in western blot on human samples at 1:1000 (fig 4a). Cell Commun Signal (2021) ncbi
mouse monoclonal (21A11AE7)
  • western blot; mouse; 1:1000; loading ...; fig 4d
Abcam SDHB antibody (Abcam, ab14714) was used in western blot on mouse samples at 1:1000 (fig 4d). Nat Commun (2021) ncbi
mouse monoclonal (21A11AE7)
  • western blot; mouse; 1:1000; loading ...; fig 4m
Abcam SDHB antibody (Abcam, Ab14714) was used in western blot on mouse samples at 1:1000 (fig 4m). elife (2021) ncbi
mouse monoclonal (21A11AE7)
  • western blot knockout validation; human; fig 2b
Abcam SDHB antibody (Abcam, ab14714) was used in western blot knockout validation on human samples (fig 2b). Front Endocrinol (Lausanne) (2021) ncbi
mouse monoclonal (21A11AE7)
  • western blot; human; loading ...; fig 2c
Abcam SDHB antibody (Abcam, ab14714) was used in western blot on human samples (fig 2c). J Biol Chem (2021) ncbi
mouse monoclonal (21A11AE7)
  • immunohistochemistry - paraffin section; human; 1:100; fig 5o
Abcam SDHB antibody (Abcam, 21A11AE7) was used in immunohistochemistry - paraffin section on human samples at 1:100 (fig 5o). Acta Neuropathol (2020) ncbi
mouse monoclonal (21A11AE7)
  • western blot; mouse; 1:2000; loading ...; fig 3h
Abcam SDHB antibody (Abcam, ab14714) was used in western blot on mouse samples at 1:2000 (fig 3h). elife (2020) ncbi
mouse monoclonal (21A11AE7)
  • western blot; human; 1:500-1:2000; loading ...; fig 5c
Abcam SDHB antibody (Abcam, ab14714) was used in western blot on human samples at 1:500-1:2000 (fig 5c). Cell Rep (2019) ncbi
mouse monoclonal (21A11AE7)
  • immunocytochemistry; mouse; loading ...; fig 5c
Abcam SDHB antibody (ABCAM, 21A11AE7) was used in immunocytochemistry on mouse samples (fig 5c). Arch Immunol Ther Exp (Warsz) (2019) ncbi
mouse monoclonal (21A11AE7)
  • western blot; human; loading ...; fig 1a
  • western blot; mouse; loading ...; fig 1b
Abcam SDHB antibody (Abcam, ab14714) was used in western blot on human samples (fig 1a) and in western blot on mouse samples (fig 1b). Haematologica (2019) ncbi
mouse monoclonal (21A11AE7)
  • western blot; mouse; 1:10,000; loading ...; fig 3e
Abcam SDHB antibody (Abcam, ab14714) was used in western blot on mouse samples at 1:10,000 (fig 3e). EMBO Mol Med (2019) ncbi
mouse monoclonal (21A11AE7)
  • western blot; human; 1:2000; loading ...; fig 1g
Abcam SDHB antibody (Abcam, 14714) was used in western blot on human samples at 1:2000 (fig 1g). J Clin Invest (2017) ncbi
mouse monoclonal (21A11AE7)
  • western blot knockout validation; human; loading ...; fig 1a
Abcam SDHB antibody (Abcam, ab14714) was used in western blot knockout validation on human samples (fig 1a). Oncotarget (2017) ncbi
mouse monoclonal (21A11AE7)
  • western blot; mouse; 1:1000; loading ...; fig st3
In order to find the E3 ubiquitin ligase Mule is essential for cardiac homeostasis by regulating mitochondrial function via maintenance of Pgc-1alpha and Pink1 expression and persistent negative regulation of c-Myc, Abcam SDHB antibody (Abcam, ab14714) was used in western blot on mouse samples at 1:1000 (fig st3). Sci Rep (2017) ncbi
mouse monoclonal (21A11AE7)
  • western blot; human; loading ...; fig 6a
In order to test if electron transport chain disruption eliminates Her2-high disease, Abcam SDHB antibody (Abcam, ab14714) was used in western blot on human samples (fig 6a). Antioxid Redox Signal (2017) ncbi
mouse monoclonal (21A11AE7)
  • western blot; mouse; fig 1
Abcam SDHB antibody (Abcam, 21A11AE7) was used in western blot on mouse samples (fig 1). Cell Death Discov (2016) ncbi
mouse monoclonal (21A11AE7)
  • western blot; mouse; 500 ug/ml; fig 2
In order to investigate the impact of neuronal Atg7 depletion using a mouse model of severe neonatal hypoxia-ischemia, Abcam SDHB antibody (Abcam, ab14714) was used in western blot on mouse samples at 500 ug/ml (fig 2). Autophagy (2016) ncbi
mouse monoclonal (21A11AE7)
  • immunohistochemistry; mouse; 1:1000; loading ...; fig S8
Abcam SDHB antibody (Abcam, ab14714) was used in immunohistochemistry on mouse samples at 1:1000 (fig S8). PLoS ONE (2015) ncbi
mouse monoclonal (21A11AE7)
  • western blot; mouse; 1:250; loading ...; fig 3d
Abcam SDHB antibody (Abcam, Ab14714) was used in western blot on mouse samples at 1:250 (fig 3d). Sci Rep (2015) ncbi
mouse monoclonal (21A11AE7)
  • immunohistochemistry - paraffin section; mouse
In order to study the role of PTPIP51 in memory processing, Abcam SDHB antibody (abcam, ab14714) was used in immunohistochemistry - paraffin section on mouse samples . Mol Cell Neurosci (2015) ncbi
mouse monoclonal (21A11AE7)
  • western blot; mouse
In order to study the correlation between cardiac mitochondrial dysfunction and the high fat, high sucrose diet, Abcam SDHB antibody (Abcam, ab14714) was used in western blot on mouse samples . J Mol Cell Cardiol (2015) ncbi
mouse monoclonal (21A11AE7)
  • immunohistochemistry; human; 1:100
Abcam SDHB antibody (Abcam, ab14714) was used in immunohistochemistry on human samples at 1:100. Am J Surg Pathol (2014) ncbi
mouse monoclonal (21A11AE7)
  • western blot; human
In order to investigate the effects of regular football training in men with type 2 diabetes mellitus, Abcam SDHB antibody (Abcam, ab14714) was used in western blot on human samples . Scand J Med Sci Sports (2014) ncbi
mouse monoclonal (21A11AE7)
  • immunohistochemistry - paraffin section; human; 1:100
Abcam SDHB antibody (Abcam, ab14714) was used in immunohistochemistry - paraffin section on human samples at 1:100. Am J Surg Pathol (2014) ncbi
mouse monoclonal (21A11AE7)
  • western blot; human; 1:250
Abcam SDHB antibody (Abcam, Ab14714) was used in western blot on human samples at 1:250. FASEB J (2014) ncbi
mouse monoclonal (21A11AE7)
  • western blot; rat
  • western blot; human
  • western blot; mouse
Abcam SDHB antibody (Abcam, ab14714) was used in western blot on rat samples , in western blot on human samples and in western blot on mouse samples . PLoS ONE (2013) ncbi
mouse monoclonal (21A11AE7)
  • immunohistochemistry - paraffin section; human; 1:3000
Abcam SDHB antibody (Abcam, ab14714) was used in immunohistochemistry - paraffin section on human samples at 1:3000. Acta Neuropathol (2013) ncbi
mouse monoclonal (21A11AE7)
  • immunohistochemistry; human; 1:1000; tbl 1
In order to report on a case of plexiform fibromyxoma of the stomach, Abcam SDHB antibody (Abcam, 21A11) was used in immunohistochemistry on human samples at 1:1000 (tbl 1). Int J Surg Pathol (2014) ncbi
mouse monoclonal (21A11AE7)
  • western blot; human
Abcam SDHB antibody (Abcam, ab14714) was used in western blot on human samples . J Biol Chem (2012) ncbi
Invitrogen
mouse monoclonal (21A11AE7)
  • immunocytochemistry; human; 1:500; fig 4b
In order to discover the development of mitochondria during prolonged in vitro culturing of human pluripotent stem cells derived cardiomyocytes, Invitrogen SDHB antibody (Invitrogen, 459230) was used in immunocytochemistry on human samples at 1:500 (fig 4b). Stem Cells Int (2017) ncbi
mouse monoclonal (21A11AE7)
  • western blot; mouse; 1:1000; fig 5
In order to find the function of transcriptional coregulator PGC-1beta in mitochondria and anti-oxidant defense in skeletal muscles, Invitrogen SDHB antibody (Invitrogen, 459230) was used in western blot on mouse samples at 1:1000 (fig 5). Nat Commun (2015) ncbi
mouse monoclonal (21A11AE7)
  • western blot; mouse; 1:4000
In order to assess the use of gene therapy in treating Friedreich's ataxia cardiomyopathy in a mouse model, Invitrogen SDHB antibody (Invitrogen, 459230) was used in western blot on mouse samples at 1:4000. Nat Med (2014) ncbi
mouse monoclonal (21A11AE7)
  • western blot; rat; fig 9
In order to test if and how MsrA affects retinal pigment epithelium functionality, Invitrogen SDHB antibody (Invitrogen, 21A11AE7) was used in western blot on rat samples (fig 9). Free Radic Biol Med (2013) ncbi
mouse monoclonal (21A11AE7)
  • western blot; human; fig 11
In order to identify compounds that are toxic to succinate dehydrogenase mutant cells using a yeast model of paraganglioma, Invitrogen SDHB antibody (Invitrogen, 459230) was used in western blot on human samples (fig 11). PLoS ONE (2013) ncbi
mouse monoclonal (21A11AE7)
  • western blot; mouse; fig 2
In order to test if the increases in PGC-1alpha and mitochondrial biogenesis induced by endurance exercise are mediated by catecholamines, Invitrogen SDHB antibody (Invitrogen, 459230) was used in western blot on mouse samples (fig 2). Am J Physiol Endocrinol Metab (2013) ncbi
Articles Reviewed
  1. Sabbir M, Taylor C, Zahradka P. CAMKK2 regulates mitochondrial function by controlling succinate dehydrogenase expression, post-translational modification, megacomplex assembly, and activity in a cell-type-specific manner. Cell Commun Signal. 2021;19:98 pubmed publisher
  2. Sato M, Kadomatsu T, Miyata K, Warren J, Tian Z, Zhu S, et al. The lncRNA Caren antagonizes heart failure by inactivating DNA damage response and activating mitochondrial biogenesis. Nat Commun. 2021;12:2529 pubmed publisher
  3. Pereira R, Marti A, Olvera A, Tadinada S, Bjorkman S, Weatherford E, et al. OPA1 deletion in brown adipose tissue improves thermoregulation and systemic metabolism via FGF21. elife. 2021;10: pubmed publisher
  4. Matlac D, Hadrava Vanova K, Bechmann N, Richter S, Folberth J, Ghayee H, et al. Succinate Mediates Tumorigenic Effects via Succinate Receptor 1: Potential for New Targeted Treatment Strategies in Succinate Dehydrogenase Deficient Paragangliomas. Front Endocrinol (Lausanne). 2021;12:589451 pubmed publisher
  5. Jin X, Zhang Z, Nie Z, Wang C, Meng F, Yi Q, et al. An animal model for mitochondrial tyrosyl-tRNA synthetase deficiency reveals links between oxidative phosphorylation and retinal function. J Biol Chem. 2021;296:100437 pubmed publisher
  6. Schweizer L, Thierfelder F, Thomas C, Soschinski P, Suwala A, Stichel D, et al. Molecular characterization of CNS paragangliomas identifies cauda equina paragangliomas as a distinct tumor entity. Acta Neuropathol. 2020;140:893-906 pubmed publisher
  7. Nowinski S, Solmonson A, Rusin S, Maschek J, Bensard C, Fogarty S, et al. Mitochondrial fatty acid synthesis coordinates oxidative metabolism in mammalian mitochondria. elife. 2020;9: pubmed publisher
  8. Wall C, Rose C, Adrian M, Zeng Y, Kirkpatrick D, Bingol B. PPEF2 Opposes PINK1-Mediated Mitochondrial Quality Control by Dephosphorylating Ubiquitin. Cell Rep. 2019;29:3280-3292.e7 pubmed publisher
  9. Wyżewski Z, Gregorczyk Zboroch K, Mielcarska M, Bossowska Nowicka M, Struzik J, Szczepanowska J, et al. Mitochondrial Heat Shock Response Induced by Ectromelia Virus is Accompanied by Reduced Apoptotic Potential in Murine L929 Fibroblasts. Arch Immunol Ther Exp (Warsz). 2019;67:401-414 pubmed publisher
  10. Maio N, Kim K, Holmes Hampton G, Singh A, Rouault T. Dimeric ferrochelatase bridges ABCB7 and ABCB10 homodimers in an architecturally defined molecular complex required for heme biosynthesis. Haematologica. 2019;: pubmed publisher
  11. Signes A, Cerutti R, Dickson A, Benincá C, Hinchy E, Ghezzi D, et al. APOPT1/COA8 assists COX assembly and is oppositely regulated by UPS and ROS. EMBO Mol Med. 2019;11: pubmed publisher
  12. Caino M, Seo J, Wang Y, Rivadeneira D, Gabrilovich D, Kim E, et al. Syntaphilin controls a mitochondrial rheostat for proliferation-motility decisions in cancer. J Clin Invest. 2017;127:3755-3769 pubmed publisher
  13. Kitazawa S, Ebara S, Ando A, Baba Y, Satomi Y, Soga T, et al. Succinate dehydrogenase B-deficient cancer cells are highly sensitive to bromodomain and extra-terminal inhibitors. Oncotarget. 2017;8:28922-28938 pubmed publisher
  14. Dai D, Danoviz M, Wiczer B, Laflamme M, Tian R. Mitochondrial Maturation in Human Pluripotent Stem Cell Derived Cardiomyocytes. Stem Cells Int. 2017;2017:5153625 pubmed publisher
  15. Dadson K, Hauck L, Hao Z, Grothe D, Rao V, Mak T, et al. The E3 ligase Mule protects the heart against oxidative stress and mitochondrial dysfunction through Myc-dependent inactivation of Pgc-1α and Pink1. Sci Rep. 2017;7:41490 pubmed publisher
  16. Rohlenova K, Sachaphibulkij K, Stursa J, Bezawork Geleta A, Blecha J, Endaya B, et al. Selective Disruption of Respiratory Supercomplexes as a New Strategy to Suppress Her2high Breast Cancer. Antioxid Redox Signal. 2017;26:84-103 pubmed publisher
  17. Lopez Cruzan M, Sharma R, Tiwari M, Karbach S, Holstein D, Martin C, et al. Caspase-2 resides in the mitochondria and mediates apoptosis directly from the mitochondrial compartment. Cell Death Discov. 2016;2: pubmed
  18. Xie C, Ginet V, Sun Y, Koike M, Zhou K, Li T, et al. Neuroprotection by selective neuronal deletion of Atg7 in neonatal brain injury. Autophagy. 2016;12:410-23 pubmed publisher
  19. Gali Ramamoorthy T, Laverny G, Schlagowski A, Zoll J, Messaddeq N, Bornert J, et al. The transcriptional coregulator PGC-1β controls mitochondrial function and anti-oxidant defence in skeletal muscles. Nat Commun. 2015;6:10210 pubmed publisher
  20. Her Y, Nelson Holte M, MAHER L. Oxygen concentration controls epigenetic effects in models of familial paraganglioma. PLoS ONE. 2015;10:e0127471 pubmed publisher
  21. Gouspillou G, Scheede Bergdahl C, Spendiff S, Vuda M, Meehan B, Mlynarski H, et al. Anthracycline-containing chemotherapy causes long-term impairment of mitochondrial respiration and increased reactive oxygen species release in skeletal muscle. Sci Rep. 2015;5:8717 pubmed publisher
  22. Brobeil A, Viard M, Petri M, Steger K, Tag C, Wimmer M. Memory and PTPIP51--a new protein in hippocampus and cerebellum. Mol Cell Neurosci. 2015;64:61-73 pubmed publisher
  23. Sverdlov A, Elezaby A, Behring J, Bachschmid M, Luptak I, Tu V, et al. High fat, high sucrose diet causes cardiac mitochondrial dysfunction due in part to oxidative post-translational modification of mitochondrial complex II. J Mol Cell Cardiol. 2015;78:165-73 pubmed publisher
  24. Gill A, Hes O, Papathomas T, Šedivcová M, Tan P, Agaimy A, et al. Succinate dehydrogenase (SDH)-deficient renal carcinoma: a morphologically distinct entity: a clinicopathologic series of 36 tumors from 27 patients. Am J Surg Pathol. 2014;38:1588-602 pubmed publisher
  25. Andersen T, Schmidt J, Thomassen M, Hornstrup T, Frandsen U, Randers M, et al. A preliminary study: effects of football training on glucose control, body composition, and performance in men with type 2 diabetes. Scand J Med Sci Sports. 2014;24 Suppl 1:43-56 pubmed publisher
  26. Perdomini M, Belbellaa B, Monassier L, Reutenauer L, Messaddeq N, Cartier N, et al. Prevention and reversal of severe mitochondrial cardiomyopathy by gene therapy in a mouse model of Friedreich's ataxia. Nat Med. 2014;20:542-7 pubmed publisher
  27. Gill A, Toon C, Clarkson A, Sioson L, Chou A, Winship I, et al. Succinate dehydrogenase deficiency is rare in pituitary adenomas. Am J Surg Pathol. 2014;38:560-6 pubmed publisher
  28. Gouspillou G, Sgarioto N, Kapchinsky S, Purves Smith F, Norris B, Pion C, et al. Increased sensitivity to mitochondrial permeability transition and myonuclear translocation of endonuclease G in atrophied muscle of physically active older humans. FASEB J. 2014;28:1621-33 pubmed publisher
  29. Dun Y, Vargas J, Brot N, Finnemann S. Independent roles of methionine sulfoxide reductase A in mitochondrial ATP synthesis and as antioxidant in retinal pigment epithelial cells. Free Radic Biol Med. 2013;65:1340-1351 pubmed publisher
  30. Kovarova N, Mracek T, Nůsková H, Holzerová E, Vrbacky M, Pecina P, et al. High molecular weight forms of mammalian respiratory chain complex II. PLoS ONE. 2013;8:e71869 pubmed publisher
  31. Cama A, Verginelli F, Lotti L, Napolitano F, Morgano A, D Orazio A, et al. Integrative genetic, epigenetic and pathological analysis of paraganglioma reveals complex dysregulation of NOTCH signaling. Acta Neuropathol. 2013;126:575-94 pubmed publisher
  32. Lee P, Yau D, Lau P, Chan J. Plexiform fibromyxoma (plexiform angiomyxoid myofibroblastic tumor) of stomach: an unusual presentation as a fistulating abscess. Int J Surg Pathol. 2014;22:286-90 pubmed publisher
  33. Bancos I, Bida J, Tian D, Bundrick M, John K, Holte M, et al. High-throughput screening for growth inhibitors using a yeast model of familial paraganglioma. PLoS ONE. 2013;8:e56827 pubmed publisher
  34. Kim S, Asaka M, Higashida K, Takahashi Y, Holloszy J, Han D. ?-Adrenergic stimulation does not activate p38 MAP kinase or induce PGC-1? in skeletal muscle. Am J Physiol Endocrinol Metab. 2013;304:E844-52 pubmed publisher
  35. van Wietmarschen N, Moradian A, Morin G, Lansdorp P, Uringa E. The mammalian proteins MMS19, MIP18, and ANT2 are involved in cytoplasmic iron-sulfur cluster protein assembly. J Biol Chem. 2012;287:43351-8 pubmed publisher