This is a Validated Antibody Database (VAD) review about bovine RHOA, based on 31 published articles (read how Labome selects the articles), using RHOA antibody in all methods. It is aimed to help Labome visitors find the most suited RHOA antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
RHOA synonym: ARHA

Knockout validation
Cell Signaling Technology
domestic rabbit monoclonal (67B9)
  • western blot knockout validation; human; 1:1000; loading ...; fig 4s2a
Cell Signaling Technology RHOA antibody (Cell Signaling, 2117) was used in western blot knockout validation on human samples at 1:1000 (fig 4s2a). elife (2019) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (67B9)
  • western blot knockout validation; human; 1:1000; loading ...; fig 4s2a
Cell Signaling Technology RHOA antibody (Cell Signaling, 2117) was used in western blot knockout validation on human samples at 1:1000 (fig 4s2a). elife (2019) ncbi
domestic rabbit monoclonal (67B9)
  • western blot; mouse; loading ...; fig s1d
Cell Signaling Technology RHOA antibody (Cell Signaling, 2117) was used in western blot on mouse samples (fig s1d). Sci Adv (2019) ncbi
domestic rabbit monoclonal (67B9)
  • western blot; human; loading ...; fig 3f
Cell Signaling Technology RHOA antibody (Cell Signaling, 2117) was used in western blot on human samples (fig 3f). Cancer Cell Int (2019) ncbi
domestic rabbit monoclonal (67B9)
  • western blot; human; 1:2000; loading ...; fig 5b
Cell Signaling Technology RHOA antibody (CST, 2117) was used in western blot on human samples at 1:2000 (fig 5b). Nat Commun (2019) ncbi
domestic rabbit monoclonal (67B9)
  • western blot; human; loading ...; fig 3e
Cell Signaling Technology RHOA antibody (Cell Signaling Technology, 2117S) was used in western blot on human samples (fig 3e). J Clin Invest (2019) ncbi
domestic rabbit monoclonal (67B9)
  • western blot; human; 1:2000; loading ...; fig 3a
Cell Signaling Technology RHOA antibody (Cell Signaling, 2117) was used in western blot on human samples at 1:2000 (fig 3a). EMBO Mol Med (2018) ncbi
domestic rabbit monoclonal (67B9)
  • western blot; mouse; fig 3c
Cell Signaling Technology RHOA antibody (Cell Signaling, 2117) was used in western blot on mouse samples (fig 3c). FASEB J (2018) ncbi
domestic rabbit monoclonal (67B9)
  • western blot; mouse; 1:1000; loading ...; fig 2a
Cell Signaling Technology RHOA antibody (Cell Signaling Technology, 2117) was used in western blot on mouse samples at 1:1000 (fig 2a). Nature (2017) ncbi
domestic rabbit monoclonal (67B9)
  • western blot; human; loading ...; fig 2b
In order to observe that chronic presence of internalized Escherichia coli leads to enhanced oncogenicity in colon cancer cells, Cell Signaling Technology RHOA antibody (cell signalling, 2117) was used in western blot on human samples (fig 2b). Cell Death Dis (2017) ncbi
domestic rabbit monoclonal (67B9)
  • western blot; human; 1:400; loading ...; fig s5d
In order to describe the reverse signaling pathway of the Plexin-B1/Sema4A interaction involved in cell migration., Cell Signaling Technology RHOA antibody (Cell signaling, 67B9) was used in western blot on human samples at 1:400 (fig s5d). J Cell Biol (2017) ncbi
domestic rabbit monoclonal (67B9)
  • western blot; mouse; 1:1000; loading ...; fig 5b
In order to investigate the interaction between SPARC and the actin cytoskeleton, Cell Signaling Technology RHOA antibody (Cell Signaling, 2117) was used in western blot on mouse samples at 1:1000 (fig 5b). Am J Pathol (2017) ncbi
domestic rabbit monoclonal (67B9)
  • western blot; human; loading ...; fig 6a
Cell Signaling Technology RHOA antibody (Cell signaling, 2117P) was used in western blot on human samples (fig 6a). Oncotarget (2016) ncbi
domestic rabbit monoclonal (67B9)
  • western blot; dogs; 1:500; fig s1d
Cell Signaling Technology RHOA antibody (Cell Signaling, 2117) was used in western blot on dogs samples at 1:500 (fig s1d). J Am Heart Assoc (2016) ncbi
domestic rabbit monoclonal (67B9)
  • western blot; human; fig 4b
Cell Signaling Technology RHOA antibody (Cell Signaling, 2117) was used in western blot on human samples (fig 4b). Oncotarget (2016) ncbi
domestic rabbit monoclonal (67B9)
  • western blot; zebrafish ; 1:500; fig 9
Cell Signaling Technology RHOA antibody (Cell Signaling, 2117) was used in western blot on zebrafish samples at 1:500 (fig 9). Development (2016) ncbi
domestic rabbit monoclonal (67B9)
  • western blot; human; 1:1000; loading ...; fig 3e
Cell Signaling Technology RHOA antibody (Cell Signaling, 2117) was used in western blot on human samples at 1:1000 (fig 3e). Oncotarget (2016) ncbi
domestic rabbit monoclonal (67B9)
  • western blot; human; fig 4
In order to study suppression invasion by reduction of intracellular GTP pools via a microphthalmia-associated transcription factor, Cell Signaling Technology RHOA antibody (Cell Signaling, 2117) was used in western blot on human samples (fig 4). Oncogene (2017) ncbi
domestic rabbit monoclonal (67B9)
  • western blot; rat; loading ...; fig 2a
In order to report that mammalian actin-binding protein-1 and FHL2 are binding partners that regulate Rho GTPase signaling and breast cancer cell invasion, Cell Signaling Technology RHOA antibody (Cell Signaling, 67B9) was used in western blot on rat samples (fig 2a). J Biol Chem (2016) ncbi
domestic rabbit monoclonal (67B9)
  • western blot; human; 1:1000; fig 4
In order to learn regulation of actin network architecture and ciliogenesis due to STAR syndrome-associated CDK10/Cyclin M, Cell Signaling Technology RHOA antibody (Cell signaling, 2117) was used in western blot on human samples at 1:1000 (fig 4). Cell Cycle (2016) ncbi
domestic rabbit monoclonal (67B9)
  • western blot; human; loading ...; fig 2a
Cell Signaling Technology RHOA antibody (Cell Signaling, 2117) was used in western blot on human samples (fig 2a). Oncotarget (2016) ncbi
domestic rabbit monoclonal (67B9)
  • western blot; human; fig 2
Cell Signaling Technology RHOA antibody (Cell Signaling, 2117) was used in western blot on human samples (fig 2). Mol Biol Cell (2016) ncbi
domestic rabbit monoclonal (67B9)
  • western blot; mouse; fig s4
In order to elucidate the revelation of Beta2 integrin-mediated cytoskeletal rearrangement in vascular endothelial growth factor (VEGF)- induced retinal vascular hyperpermeability by quantitative proteomics, Cell Signaling Technology RHOA antibody (Cell Signaling, 2117) was used in western blot on mouse samples (fig s4). Mol Cell Proteomics (2016) ncbi
domestic rabbit monoclonal (67B9)
  • western blot; human; fig 5
In order to investigate proteolytic processing of p27, Cell Signaling Technology RHOA antibody (Cell Signaling, 2117) was used in western blot on human samples (fig 5). Oncogene (2016) ncbi
domestic rabbit monoclonal (67B9)
  • western blot; human; 1:1000; fig s1
Cell Signaling Technology RHOA antibody (Cell Signaling, 67B9) was used in western blot on human samples at 1:1000 (fig s1). Nat Commun (2016) ncbi
domestic rabbit monoclonal (67B9)
  • western blot; human; fig 4
Cell Signaling Technology RHOA antibody (Cell Signaling, 2117) was used in western blot on human samples (fig 4). Oncogene (2016) ncbi
domestic rabbit monoclonal (67B9)
  • western blot; human
In order to report that inhibition of eIF5A reduces pancreatic ductal adenocarcinoma cell migration, invasion, and metastasis in vitro and in vivo, Cell Signaling Technology RHOA antibody (Cell Signaling Technology, #2117) was used in western blot on human samples . J Biol Chem (2015) ncbi
domestic rabbit monoclonal (67B9)
  • western blot; human; 1:250; loading ...; fig 3g
Cell Signaling Technology RHOA antibody (Cell Signaling, 67B9) was used in western blot on human samples at 1:250 (fig 3g). J Cell Biol (2015) ncbi
domestic rabbit monoclonal (67B9)
  • western blot; human; fig 1
Cell Signaling Technology RHOA antibody (Cell Signaling Technology, 67B9) was used in western blot on human samples (fig 1). J Biol Chem (2015) ncbi
domestic rabbit monoclonal (67B9)
  • western blot; human; fig 3a
Cell Signaling Technology RHOA antibody (Cell Signaling Technology, 2117) was used in western blot on human samples (fig 3a). Oncogene (2015) ncbi
domestic rabbit monoclonal (67B9)
  • western blot; mouse
  • western blot; guinea pig
Cell Signaling Technology RHOA antibody (Cell Signaling Technology, 2117S) was used in western blot on mouse samples and in western blot on guinea pig samples . Am J Respir Cell Mol Biol (2014) ncbi
domestic rabbit monoclonal (67B9)
  • western blot; mouse; fig 3
Cell Signaling Technology RHOA antibody (Cell Signaling, 67B9) was used in western blot on mouse samples (fig 3). EMBO Mol Med (2014) ncbi
Articles Reviewed
  1. Zeng H, Castillo Cabrera J, Manser M, Lu B, Yang Z, Strande V, et al. Genome-wide CRISPR screening reveals genetic modifiers of mutant EGFR dependence in human NSCLC. elife. 2019;8: pubmed publisher
  2. Yang S, Harding A, Sweeney C, Miao D, Swan G, Zhou C, et al. Control of antiviral innate immune response by protein geranylgeranylation. Sci Adv. 2019;5:eaav7999 pubmed publisher
  3. Liu Y, Wang X, Deng L, Ping L, Shi Y, Zheng W, et al. ITK inhibition induced in vitro and in vivo anti-tumor activity through downregulating TCR signaling pathway in malignant T cell lymphoma. Cancer Cell Int. 2019;19:32 pubmed publisher
  4. Mathieu J, Detraux D, Kuppers D, Wang Y, Cavanaugh C, Sidhu S, et al. Folliculin regulates mTORC1/2 and WNT pathways in early human pluripotency. Nat Commun. 2019;10:632 pubmed publisher
  5. Bouafia A, Lofek S, Bruneau J, Chentout L, Lamrini H, Trinquand A, et al. Loss of ARHGEF1 causes a human primary antibody deficiency. J Clin Invest. 2019;129:1047-1060 pubmed publisher
  6. Greenhough A, Bagley C, Heesom K, Gurevich D, Gay D, Bond M, et al. Cancer cell adaptation to hypoxia involves a HIF-GPRC5A-YAP axis. EMBO Mol Med. 2018;10: pubmed publisher
  7. Khalifeh Soltani A, Gupta D, Ha A, Podolsky M, Datta R, Atabai K. The Mfge8-α8β1-PTEN pathway regulates airway smooth muscle contraction in allergic inflammation. FASEB J. 2018;:fj201800109R pubmed publisher
  8. Escamilla C, Filonova I, Walker A, Xuan Z, Holehonnur R, Espinosa F, et al. Kctd13 deletion reduces synaptic transmission via increased RhoA. Nature. 2017;551:227-231 pubmed publisher
  9. Sahu U, Choudhury A, Parvez S, Biswas S, Kar S. Induction of intestinal stemness and tumorigenicity by aberrant internalization of commensal non-pathogenic E. coli. Cell Death Dis. 2017;8:e2667 pubmed publisher
  10. Sun T, Yang L, Kaur H, Pestel J, Looso M, Nolte H, et al. A reverse signaling pathway downstream of Sema4A controls cell migration via Scrib. J Cell Biol. 2017;216:199-215 pubmed publisher
  11. Jørgensen L, Jepsen P, Boysen A, Dalgaard L, Hvid L, Ørtenblad N, et al. SPARC Interacts with Actin in Skeletal Muscle in Vitro and in Vivo. Am J Pathol. 2017;187:457-474 pubmed publisher
  12. Liu Z, Chu S, Yao S, Li Y, Fan S, Sun X, et al. CD74 interacts with CD44 and enhances tumorigenesis and metastasis via RHOA-mediated cofilin phosphorylation in human breast cancer cells. Oncotarget. 2016;7:68303-68313 pubmed publisher
  13. Hammers D, Sleeper M, Forbes S, Shima A, Walter G, Sweeney H. Tadalafil Treatment Delays the Onset of Cardiomyopathy in Dystrophin-Deficient Hearts. J Am Heart Assoc. 2016;5: pubmed publisher
  14. Hatem R, El Botty R, Chateau Joubert S, Servely J, Labiod D, de Plater L, et al. Targeting mTOR pathway inhibits tumor growth in different molecular subtypes of triple-negative breast cancers. Oncotarget. 2016;7:48206-48219 pubmed publisher
  15. Zhang J, Jiang Z, Liu X, Meng A. Eph/ephrin signaling maintains the boundary of dorsal forerunner cell cluster during morphogenesis of the zebrafish embryonic left-right organizer. Development. 2016;143:2603-15 pubmed publisher
  16. Zuckerwise L, Li J, Lu L, Men Y, Geng T, Buhimschi C, et al. H19 long noncoding RNA alters trophoblast cell migration and invasion by regulating TβR3 in placentae with fetal growth restriction. Oncotarget. 2016;7:38398-38407 pubmed publisher
  17. Bianchi Smiraglia A, Bagati A, Fink E, Moparthy S, Wawrzyniak J, Marvin E, et al. Microphthalmia-associated transcription factor suppresses invasion by reducing intracellular GTP pools. Oncogene. 2017;36:84-96 pubmed publisher
  18. Boateng L, Bennin D, de Oliveira S, Huttenlocher A. Mammalian Actin-binding Protein-1/Hip-55 Interacts with FHL2 and Negatively Regulates Cell Invasion. J Biol Chem. 2016;291:13987-98 pubmed publisher
  19. Guen V, Gamble C, Perez D, Bourassa S, Zappel H, Gartner J, et al. STAR syndrome-associated CDK10/Cyclin M regulates actin network architecture and ciliogenesis. Cell Cycle. 2016;15:678-88 pubmed publisher
  20. von Mässenhausen A, SANDERS C, Thewes B, Deng M, Queisser A, Vogel W, et al. MERTK as a novel therapeutic target in head and neck cancer. Oncotarget. 2016;7:32678-94 pubmed publisher
  21. Scott D, Tolbert C, Burridge K. Tension on JAM-A activates RhoA via GEF-H1 and p115 RhoGEF. Mol Biol Cell. 2016;27:1420-30 pubmed publisher
  22. Jo D, Bae J, Chae S, Kim J, Han J, Hwang D, et al. Quantitative Proteomics Reveals β2 Integrin-mediated Cytoskeletal Rearrangement in Vascular Endothelial Growth Factor (VEGF)-induced Retinal Vascular Hyperpermeability. Mol Cell Proteomics. 2016;15:1681-91 pubmed publisher
  23. Podmirseg S, Jäkel H, Ranches G, Kullmann M, Sohm B, Villunger A, et al. Caspases uncouple p27(Kip1) from cell cycle regulated degradation and abolish its ability to stimulate cell migration and invasion. Oncogene. 2016;35:4580-90 pubmed publisher
  24. Heemskerk N, Schimmel L, Oort C, van Rijssel J, Yin T, Ma B, et al. F-actin-rich contractile endothelial pores prevent vascular leakage during leukocyte diapedesis through local RhoA signalling. Nat Commun. 2016;7:10493 pubmed publisher
  25. O Hayre M, Inoue A, Kufareva I, Wang Z, Mikelis C, Drummond R, et al. Inactivating mutations in GNA13 and RHOA in Burkitt's lymphoma and diffuse large B-cell lymphoma: a tumor suppressor function for the Gα13/RhoA axis in B cells. Oncogene. 2016;35:3771-80 pubmed publisher
  26. Fujimura K, Choi S, Wyse M, Strnadel J, Wright T, Klemke R. Eukaryotic Translation Initiation Factor 5A (EIF5A) Regulates Pancreatic Cancer Metastasis by Modulating RhoA and Rho-associated Kinase (ROCK) Protein Expression Levels. J Biol Chem. 2015;290:29907-19 pubmed publisher
  27. Leyme A, Marivin A, Perez Gutierrez L, Nguyen L, Garcia Marcos M. Integrins activate trimeric G proteins via the nonreceptor protein GIV/Girdin. J Cell Biol. 2015;210:1165-84 pubmed publisher
  28. Ibeawuchi S, Agbor L, Quelle F, Sigmund C. Hypertension-causing Mutations in Cullin3 Protein Impair RhoA Protein Ubiquitination and Augment the Association with Substrate Adaptors. J Biol Chem. 2015;290:19208-17 pubmed publisher
  29. Liu X, Yao J, Tripathi D, Ding Z, Xu Y, Sun M, et al. Autophagy mediates HIF2α degradation and suppresses renal tumorigenesis. Oncogene. 2015;34:2450-60 pubmed publisher
  30. Cheng Y, Cao A, Zheng J, Wang H, Sun Y, Liu C, et al. Airway hyperresponsiveness induced by repeated esophageal infusion of HCl in guinea pigs. Am J Respir Cell Mol Biol. 2014;51:701-8 pubmed publisher
  31. Arroyo A, Camoletto P, Morando L, Sassoè Pognetto M, Giustetto M, Van Veldhoven P, et al. Pharmacological reversion of sphingomyelin-induced dendritic spine anomalies in a Niemann Pick disease type A mouse model. EMBO Mol Med. 2014;6:398-413 pubmed publisher