This is a Validated Antibody Database (VAD) review about bovine PIK3CA, based on 68 published articles (read how Labome selects the articles), using PIK3CA antibody in all methods. It is aimed to help Labome visitors find the most suited PIK3CA antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Knockout validation
Cell Signaling Technology
domestic rabbit monoclonal (C73F8)
  • western blot knockout validation; mouse; fig s1a
Cell Signaling Technology PIK3CA antibody (Cell Signaling Technology, 4249S) was used in western blot knockout validation on mouse samples (fig s1a). J Clin Invest (2019) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (C73F8)
  • western blot knockout validation; human; loading ...; fig 4a
  • immunoprecipitation; human; loading ...; fig 1d
Cell Signaling Technology PIK3CA antibody (Cell Signaling Technology, 4249S) was used in western blot knockout validation on human samples (fig 4a) and in immunoprecipitation on human samples (fig 1d). mSphere (2017) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (C73F8)
  • western blot knockout validation; mouse; fig 1
In order to elucidate the compartmentalization of p110alpha and p110beta, Cell Signaling Technology PIK3CA antibody (Cell Signaling, 4249) was used in western blot knockout validation on mouse samples (fig 1). elife (2016) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (C73F8)
  • western blot knockout validation; mouse; 1:1000; fig s1
Cell Signaling Technology PIK3CA antibody (Cell Signaling Tech, 4249) was used in western blot knockout validation on mouse samples at 1:1000 (fig s1). Nat Commun (2015) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (C73F8)
  • western blot; human; 1:1000; loading ...; fig 4a
Cell Signaling Technology PIK3CA antibody (cST, 4249) was used in western blot on human samples at 1:1000 (fig 4a). Cell Death Dis (2021) ncbi
domestic rabbit monoclonal (C73F8)
  • western blot; mouse; 1:1000; loading ...; fig 6d
Cell Signaling Technology PIK3CA antibody (CST, 4249) was used in western blot on mouse samples at 1:1000 (fig 6d). J Exp Clin Cancer Res (2021) ncbi
domestic rabbit monoclonal (C73F8)
  • western blot; mouse; 1:1000; loading ...; fig 2a
  • western blot; human; 1:1000; loading ...; fig 2b
Cell Signaling Technology PIK3CA antibody (Cell Signaling, 4249) was used in western blot on mouse samples at 1:1000 (fig 2a) and in western blot on human samples at 1:1000 (fig 2b). Adv Sci (Weinh) (2021) ncbi
domestic rabbit monoclonal (C73F8)
  • western blot; mouse; 1:1000; loading ...; fig 4f
Cell Signaling Technology PIK3CA antibody (Cell Signalling Technology, 4249) was used in western blot on mouse samples at 1:1000 (fig 4f). elife (2021) ncbi
domestic rabbit polyclonal
  • western blot; human; fig 1c
Cell Signaling Technology PIK3CA antibody (Cell Signaling, 4255) was used in western blot on human samples (fig 1c). Am J Cancer Res (2021) ncbi
domestic rabbit monoclonal (C73F8)
  • western blot; rat; loading ...; fig 6a
Cell Signaling Technology PIK3CA antibody (Cell Signaling, 4249) was used in western blot on rat samples (fig 6a). J Inflamm Res (2021) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:2000; loading ...
Cell Signaling Technology PIK3CA antibody (Cell Signaling Technology, 4255 S) was used in western blot on human samples at 1:2000. Nat Commun (2021) ncbi
domestic rabbit monoclonal (C73F8)
  • immunocytochemistry; human; 1:100; loading ...; fig 4c
  • western blot; human; 1:1000; loading ...; fig 4b
Cell Signaling Technology PIK3CA antibody (CST, 4249) was used in immunocytochemistry on human samples at 1:100 (fig 4c) and in western blot on human samples at 1:1000 (fig 4b). Cell Death Dis (2021) ncbi
domestic rabbit monoclonal (C73F8)
  • western blot; human; loading ...; fig 7a
Cell Signaling Technology PIK3CA antibody (CST, 4249) was used in western blot on human samples (fig 7a). Int J Biol Sci (2020) ncbi
domestic rabbit monoclonal (C73F8)
  • western blot; human; loading ...; fig 10a
  • western blot; rat; loading ...; fig 7a
Cell Signaling Technology PIK3CA antibody (Cell Signaling, 4249) was used in western blot on human samples (fig 10a) and in western blot on rat samples (fig 7a). Mol Ther Nucleic Acids (2020) ncbi
domestic rabbit monoclonal (C73F8)
  • western blot; human; 1:1000; loading ...; fig 6a
Cell Signaling Technology PIK3CA antibody (Cell Signaling, C73F8) was used in western blot on human samples at 1:1000 (fig 6a). Nat Commun (2019) ncbi
domestic rabbit monoclonal (C73F8)
  • western blot; mouse; 1:1000; loading ...; fig 2b
  • western blot; human; 1:1000; loading ...; fig 2a
Cell Signaling Technology PIK3CA antibody (Cell Signaling Technology, 4249) was used in western blot on mouse samples at 1:1000 (fig 2b) and in western blot on human samples at 1:1000 (fig 2a). Science (2019) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 5f
Cell Signaling Technology PIK3CA antibody (CST, 4255S) was used in western blot on human samples (fig 5f). Br J Cancer (2019) ncbi
domestic rabbit monoclonal (C73F8)
  • western blot; human; fig 5a
Cell Signaling Technology PIK3CA antibody (CST, 4249) was used in western blot on human samples (fig 5a). Oncogene (2020) ncbi
domestic rabbit monoclonal (C73F8)
  • western blot; human; loading ...; fig 3d
Cell Signaling Technology PIK3CA antibody (Cell Signaling, 4249) was used in western blot on human samples (fig 3d). Cell (2019) ncbi
domestic rabbit monoclonal (C73F8)
  • western blot; rat; 1:1000; loading ...; fig 6a
Cell Signaling Technology PIK3CA antibody (CST, 4249) was used in western blot on rat samples at 1:1000 (fig 6a). Cell Death Dis (2019) ncbi
domestic rabbit monoclonal (C73F8)
  • western blot knockout validation; mouse; fig s1a
Cell Signaling Technology PIK3CA antibody (Cell Signaling Technology, 4249S) was used in western blot knockout validation on mouse samples (fig s1a). J Clin Invest (2019) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:1000; loading ...; fig 1a
Cell Signaling Technology PIK3CA antibody (Cell Signaling, 4255) was used in western blot on mouse samples at 1:1000 (fig 1a). Nat Commun (2019) ncbi
domestic rabbit polyclonal
  • other; human; loading ...; fig 4c
Cell Signaling Technology PIK3CA antibody (Cell Signaling, 4255) was used in other on human samples (fig 4c). Cancer Cell (2018) ncbi
domestic rabbit monoclonal (C73F8)
  • western blot; human; loading ...; fig 7a
Cell Signaling Technology PIK3CA antibody (Cell Signaling, 4249) was used in western blot on human samples (fig 7a). Biochim Biophys Acta Mol Basis Dis (2018) ncbi
domestic rabbit monoclonal (C73F8)
  • western blot; mouse; 1:1000; loading ...; fig 3c
Cell Signaling Technology PIK3CA antibody (cell signaling, 4249) was used in western blot on mouse samples at 1:1000 (fig 3c). Oncogene (2017) ncbi
domestic rabbit monoclonal (C73F8)
  • western blot knockout validation; human; loading ...; fig 4a
  • immunoprecipitation; human; loading ...; fig 1d
Cell Signaling Technology PIK3CA antibody (Cell Signaling Technology, 4249S) was used in western blot knockout validation on human samples (fig 4a) and in immunoprecipitation on human samples (fig 1d). mSphere (2017) ncbi
domestic rabbit monoclonal (C73F8)
  • western blot; human; fig 1b
Cell Signaling Technology PIK3CA antibody (Cell Signaling, 4249) was used in western blot on human samples (fig 1b). Proc Natl Acad Sci U S A (2017) ncbi
domestic rabbit monoclonal (C73F8)
  • western blot; mouse; loading ...; fig 4a
Cell Signaling Technology PIK3CA antibody (Cell Signaling Technology, 4249) was used in western blot on mouse samples (fig 4a). elife (2017) ncbi
domestic rabbit monoclonal (C73F8)
  • western blot; human; fig 6a
Cell Signaling Technology PIK3CA antibody (Cell signaling, 4249) was used in western blot on human samples (fig 6a). Cancer Med (2017) ncbi
domestic rabbit polyclonal
  • reverse phase protein lysate microarray; human; loading ...; fig st6
In order to characterize the molecular identity of uterine carcinosarcomas., Cell Signaling Technology PIK3CA antibody (CST, 4255) was used in reverse phase protein lysate microarray on human samples (fig st6). Cancer Cell (2017) ncbi
domestic rabbit monoclonal (C73F8)
  • immunoprecipitation; human; 1:1000; loading ...; fig 4d
  • western blot; human; 1:1000; loading ...; fig 4d
Cell Signaling Technology PIK3CA antibody (Cell Signaling Technology, 4249) was used in immunoprecipitation on human samples at 1:1000 (fig 4d) and in western blot on human samples at 1:1000 (fig 4d). Oncotarget (2017) ncbi
domestic rabbit monoclonal (C73F8)
  • western blot; human; 1:1000; loading ...; fig 2b
Cell Signaling Technology PIK3CA antibody (Cell Signaling, 4249) was used in western blot on human samples at 1:1000 (fig 2b). Nat Commun (2017) ncbi
domestic rabbit monoclonal (C73F8)
  • western blot; human; 1:1000; loading ...; fig 6c
Cell Signaling Technology PIK3CA antibody (Cell Signaling, C73FB) was used in western blot on human samples at 1:1000 (fig 6c). Nat Commun (2016) ncbi
domestic rabbit monoclonal (C73F8)
  • western blot; mouse; 1:1000; loading ...; fig s9a
In order to discuss how NLRC3 protects against colorectal cancer by modulating mTor signaling, Cell Signaling Technology PIK3CA antibody (Cell Signaling, 4249) was used in western blot on mouse samples at 1:1000 (fig s9a). Nature (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; fig 5b
In order to study the effect of PIK3CA in breast cancer., Cell Signaling Technology PIK3CA antibody (Cell Signaling, 4255S) was used in western blot on human samples (fig 5b). PLoS ONE (2016) ncbi
domestic rabbit monoclonal (C73F8)
  • western blot; human; loading ...; fig 5a
Cell Signaling Technology PIK3CA antibody (Cell Signaling, 4249) was used in western blot on human samples (fig 5a). Sci Rep (2016) ncbi
domestic rabbit monoclonal (C73F8)
  • western blot; mouse; loading ...; fig 1c
In order to determine if PIK3CA mutations contribute to tumor initiation, Cell Signaling Technology PIK3CA antibody (Cell Signaling, 4249) was used in western blot on mouse samples (fig 1c). Oncogenesis (2016) ncbi
domestic rabbit monoclonal (C73F8)
  • western blot; human; loading ...; fig 6a
Cell Signaling Technology PIK3CA antibody (cell signalling, 4249) was used in western blot on human samples (fig 6a). PLoS ONE (2016) ncbi
domestic rabbit monoclonal (C73F8)
  • western blot knockout validation; mouse; fig 1
In order to elucidate the compartmentalization of p110alpha and p110beta, Cell Signaling Technology PIK3CA antibody (Cell Signaling, 4249) was used in western blot knockout validation on mouse samples (fig 1). elife (2016) ncbi
domestic rabbit monoclonal (C73F8)
  • western blot; human; fig s1
Cell Signaling Technology PIK3CA antibody (Cell Signaling, 4249) was used in western blot on human samples (fig s1). Cell Discov (2016) ncbi
domestic rabbit monoclonal (C73F8)
  • western blot; human; loading ...; fig 5A
Cell Signaling Technology PIK3CA antibody (Cell signaling, C73F8) was used in western blot on human samples (fig 5A). Oncotarget (2016) ncbi
domestic rabbit monoclonal (C73F8)
  • immunohistochemistry - paraffin section; mouse; 1:100; loading ...; fig 7e
  • immunocytochemistry; human; loading ...; fig 4c,4d
  • western blot; human; 1:1000; loading ...; fig 5,6
Cell Signaling Technology PIK3CA antibody (CST, 4249) was used in immunohistochemistry - paraffin section on mouse samples at 1:100 (fig 7e), in immunocytochemistry on human samples (fig 4c,4d) and in western blot on human samples at 1:1000 (fig 5,6). Oncotarget (2016) ncbi
domestic rabbit monoclonal (C73F8)
  • western blot; mouse; fig 5
Cell Signaling Technology PIK3CA antibody (Cell Signaling Tech, 4249) was used in western blot on mouse samples (fig 5). Mol Syst Biol (2016) ncbi
domestic rabbit monoclonal (C73F8)
  • western blot; mouse; loading ...; fig 2a
In order to examine the role of topoisomerase II in mitotic clonal expansion and adipogenesis, Cell Signaling Technology PIK3CA antibody (Cell Signaling, 4249) was used in western blot on mouse samples (fig 2a). Cell Signal (2016) ncbi
domestic rabbit monoclonal (C73F8)
  • western blot; human; loading ...; fig 4c
Cell Signaling Technology PIK3CA antibody (Cell Signaling, C73F8) was used in western blot on human samples (fig 4c). Oncotarget (2016) ncbi
domestic rabbit monoclonal (C73F8)
  • western blot; mouse; fig 6
Cell Signaling Technology PIK3CA antibody (Cell Signaling, 4249) was used in western blot on mouse samples (fig 6). Oncotarget (2016) ncbi
domestic rabbit monoclonal (C73F8)
  • western blot; human; loading ...; fig 6a
In order to study the pharmacologic inhibition of PI3K and MEK pathways in mixed cultures of human mononuclear cells., Cell Signaling Technology PIK3CA antibody (Cell Signaling, 4249) was used in western blot on human samples (fig 6a). Am J Transplant (2016) ncbi
domestic rabbit monoclonal (C73F8)
  • western blot; human; loading ...; fig 4
In order to find tumor types sensitive to phosphoinositide 3-kinase pathway inhibitors, Cell Signaling Technology PIK3CA antibody (Cell Signaling, 4249) was used in western blot on human samples (fig 4). Oncotarget (2016) ncbi
domestic rabbit polyclonal
  • western blot; mouse; fig 5
Cell Signaling Technology PIK3CA antibody (Cell Signaling, 4255) was used in western blot on mouse samples (fig 5). J Clin Invest (2016) ncbi
domestic rabbit polyclonal
  • western blot; mouse; fig 6
Cell Signaling Technology PIK3CA antibody (Cell signaling, 4255) was used in western blot on mouse samples (fig 6). Oncogene (2016) ncbi
domestic rabbit monoclonal (C73F8)
  • immunohistochemistry - paraffin section; human; fig 7
  • immunohistochemistry - paraffin section; mouse; fig 4
Cell Signaling Technology PIK3CA antibody (Cell signaling, 4249) was used in immunohistochemistry - paraffin section on human samples (fig 7) and in immunohistochemistry - paraffin section on mouse samples (fig 4). Oncogene (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; fig 1
Cell Signaling Technology PIK3CA antibody (Cell Signaling, 4255) was used in western blot on human samples (fig 1). Oncotarget (2016) ncbi
domestic rabbit monoclonal (C73F8)
  • immunohistochemistry - paraffin section; mouse; 1:200; fig s5
Cell Signaling Technology PIK3CA antibody (Cell Signaling Technology, 4249) was used in immunohistochemistry - paraffin section on mouse samples at 1:200 (fig s5). Cancer Sci (2016) ncbi
domestic rabbit monoclonal (C73F8)
  • immunocytochemistry; human; fig 3
  • western blot; human; fig 3
Cell Signaling Technology PIK3CA antibody (Cell Signalling, 4249) was used in immunocytochemistry on human samples (fig 3) and in western blot on human samples (fig 3). Oncoscience (2015) ncbi
domestic rabbit monoclonal (C73F8)
  • western blot knockout validation; mouse; 1:1000; fig s1
Cell Signaling Technology PIK3CA antibody (Cell Signaling Tech, 4249) was used in western blot knockout validation on mouse samples at 1:1000 (fig s1). Nat Commun (2015) ncbi
domestic rabbit monoclonal (C73F8)
  • western blot; human; fig 5
Cell Signaling Technology PIK3CA antibody (Cell signaling, 4249) was used in western blot on human samples (fig 5). Oncogene (2016) ncbi
domestic rabbit monoclonal (C73F8)
  • western blot; mouse; fig 3
In order to examine the effect of reelin derivatives on macrophage cholesterol metabolism, Cell Signaling Technology PIK3CA antibody (Cell Signaling, 4249) was used in western blot on mouse samples (fig 3). PLoS ONE (2015) ncbi
domestic rabbit monoclonal (C73F8)
  • western blot; rat; 1:1000; fig 3
Cell Signaling Technology PIK3CA antibody (Cell Signaling, 4249S) was used in western blot on rat samples at 1:1000 (fig 3). Exp Cell Res (2015) ncbi
domestic rabbit monoclonal (C73F8)
  • western blot; mouse; fig 3
Cell Signaling Technology PIK3CA antibody (Cell Signaling, 4249) was used in western blot on mouse samples (fig 3). EMBO Mol Med (2015) ncbi
domestic rabbit monoclonal (C73F8)
  • western blot; human; 1:1000; fig 3
Cell Signaling Technology PIK3CA antibody (Cell Signaling, 4249S) was used in western blot on human samples at 1:1000 (fig 3). Cell Death Dis (2015) ncbi
domestic rabbit monoclonal (C73F8)
  • western blot; mouse; fig 5
Cell Signaling Technology PIK3CA antibody (Cell signaling, 4249) was used in western blot on mouse samples (fig 5). Oncotarget (2015) ncbi
domestic rabbit monoclonal (C73F8)
  • western blot; rat; fig 4
Cell Signaling Technology PIK3CA antibody (Cell Signaling Technology, 4249S) was used in western blot on rat samples (fig 4). Cell Physiol Biochem (2015) ncbi
domestic rabbit monoclonal (C73F8)
  • western blot; human; fig 3
Cell Signaling Technology PIK3CA antibody (CST, 4249s) was used in western blot on human samples (fig 3). Cancer Res (2015) ncbi
domestic rabbit monoclonal (C73F8)
  • western blot; human; fig 5
Cell Signaling Technology PIK3CA antibody (Cell Signaling Technology, 4249) was used in western blot on human samples (fig 5). Sci Rep (2015) ncbi
domestic rabbit monoclonal (C73F8)
  • immunohistochemistry - paraffin section; human; 1:200; fig 1
Cell Signaling Technology PIK3CA antibody (Cell signaling, 4249) was used in immunohistochemistry - paraffin section on human samples at 1:200 (fig 1). Hum Pathol (2015) ncbi
domestic rabbit monoclonal (C73F8)
  • western blot; human; fig 1
Cell Signaling Technology PIK3CA antibody (Cell Signaling, 4249) was used in western blot on human samples (fig 1). J Biol Chem (2015) ncbi
domestic rabbit monoclonal (C73F8)
  • western blot; human; fig 5
Cell Signaling Technology PIK3CA antibody (Cell Signaling, 4249) was used in western blot on human samples (fig 5). Cell Death Dis (2015) ncbi
domestic rabbit monoclonal (C73F8)
  • western blot; human; fig 1
Cell Signaling Technology PIK3CA antibody (Cell Signaling Technologies, 4249) was used in western blot on human samples (fig 1). Mol Cell (2014) ncbi
domestic rabbit monoclonal (C73F8)
  • western blot; human; fig 4
Cell Signaling Technology PIK3CA antibody (Cell Signaling Technology, 4249) was used in western blot on human samples (fig 4). Oncol Rep (2015) ncbi
domestic rabbit monoclonal (C73F8)
  • western blot; mouse
  • western blot; human
Cell Signaling Technology PIK3CA antibody (Cell Signaling, C73F8) was used in western blot on mouse samples and in western blot on human samples . Mol Cell Biol (2014) ncbi
domestic rabbit monoclonal (C73F8)
  • western blot; rat; fig 1
Cell Signaling Technology PIK3CA antibody (Cell Signaling Technology, 4249S) was used in western blot on rat samples (fig 1). Pain (2014) ncbi
domestic rabbit monoclonal (C73F8)
  • western blot; human
Cell Signaling Technology PIK3CA antibody (Cell Signalling, 4249) was used in western blot on human samples . J Cell Sci (2013) ncbi
domestic rabbit monoclonal (C73F8)
  • western blot; human; 1:1000
Cell Signaling Technology PIK3CA antibody (Cell Signaling, 4249) was used in western blot on human samples at 1:1000. FEBS Lett (2013) ncbi
Articles Reviewed
  1. Li R, Hao Y, Wang Q, Meng Y, Wu K, Liu C, et al. ECHS1, an interacting protein of LASP1, induces sphingolipid-metabolism imbalance to promote colorectal cancer progression by regulating ceramide glycosylation. Cell Death Dis. 2021;12:911 pubmed publisher
  2. Xu X, Lei Y, Chen L, Zhou H, Liu H, Jiang J, et al. Phosphorylation of NF-κBp65 drives inflammation-mediated hepatocellular carcinogenesis and is a novel therapeutic target. J Exp Clin Cancer Res. 2021;40:253 pubmed publisher
  3. Guo J, Cheng J, Zheng N, Zhang X, Dai X, Zhang L, et al. Copper Promotes Tumorigenesis by Activating the PDK1-AKT Oncogenic Pathway in a Copper Transporter 1 Dependent Manner. Adv Sci (Weinh). 2021;8:e2004303 pubmed publisher
  4. Kearney A, Norris D, Ghomlaghi M, Kin Lok Wong M, Humphrey S, Carroll L, et al. Akt phosphorylates insulin receptor substrate to limit PI3K-mediated PIP3 synthesis. elife. 2021;10: pubmed publisher
  5. Wang J, Zhang Y, Xiao Y, Yuan X, Li P, Wang X, et al. Boosting immune surveillance by low-dose PI3K inhibitor facilitates early intervention of breast cancer. Am J Cancer Res. 2021;11:2005-2024 pubmed
  6. Chen Y, Chen Y, Jiang X, Shi M, Yang Z, Chen Z, et al. Vascular Adventitial Fibroblasts-Derived FGF10 Promotes Vascular Smooth Muscle Cells Proliferation and Migration in vitro and the Neointima Formation in vivo. J Inflamm Res. 2021;14:2207-2223 pubmed publisher
  7. Wang Z, Goto Y, Allevato M, Wu V, Saddawi Konefka R, Gilardi M, et al. Disruption of the HER3-PI3K-mTOR oncogenic signaling axis and PD-1 blockade as a multimodal precision immunotherapy in head and neck cancer. Nat Commun. 2021;12:2383 pubmed publisher
  8. Wang P, Zhao L, Gong S, Xiong S, Wang J, Zou D, et al. HIF1α/HIF2α-Sox2/Klf4 promotes the malignant progression of glioblastoma via the EGFR-PI3K/AKT signalling pathway with positive feedback under hypoxia. Cell Death Dis. 2021;12:312 pubmed publisher
  9. Zhang Y, Du P, Li Y, Zhu Q, Song X, Liu S, et al. TASP1 Promotes Gallbladder Cancer Cell Proliferation and Metastasis by Up-regulating FAM49B via PI3K/AKT Pathway. Int J Biol Sci. 2020;16:739-751 pubmed publisher
  10. Zhang Y, Mao X, Chen W, Guo X, Yu L, Jiang F, et al. A Discovery of Clinically Approved Formula FBRP for Repositioning to Treat HCC by Inhibiting PI3K/AKT/NF-κB Activation. Mol Ther Nucleic Acids. 2020;19:890-904 pubmed publisher
  11. Ghezzi C, Wong A, Chen B, Ribalet B, Damoiseaux R, Clark P. A high-throughput screen identifies that CDK7 activates glucose consumption in lung cancer cells. Nat Commun. 2019;10:5444 pubmed publisher
  12. VASAN N, Razavi P, Johnson J, Shao H, Shah H, Antoine A, et al. Double PIK3CA mutations in cis increase oncogenicity and sensitivity to PI3Kα inhibitors. Science. 2019;366:714-723 pubmed publisher
  13. Chen Q, Yang C, Chen L, Zhang J, Ge W, Yuan H, et al. YY1 targets tubulin polymerisation-promoting protein to inhibit migration, invasion and angiogenesis in pancreatic cancer via p38/MAPK and PI3K/AKT pathways. Br J Cancer. 2019;121:912-921 pubmed publisher
  14. Veschi V, Mangiapane L, Nicotra A, Di Franco S, Scavo E, Apuzzo T, et al. Targeting chemoresistant colorectal cancer via systemic administration of a BMP7 variant. Oncogene. 2020;39:987-1003 pubmed publisher
  15. Lundby A, Franciosa G, Emdal K, Refsgaard J, Gnosa S, Bekker Jensen D, et al. Oncogenic Mutations Rewire Signaling Pathways by Switching Protein Recruitment to Phosphotyrosine Sites. Cell. 2019;179:543-560.e26 pubmed publisher
  16. Luo X, Jiang X, Li J, Bai Y, Li Z, Wei P, et al. Insulin-like growth factor-1 attenuates oxidative stress-induced hepatocyte premature senescence in liver fibrogenesis via regulating nuclear p53-progerin interaction. Cell Death Dis. 2019;10:451 pubmed publisher
  17. Sivaram N, McLaughlin P, Han H, Petrenko O, Jiang Y, Ballou L, et al. Tumor-intrinsic PIK3CA represses tumor immunogenecity in a model of pancreatic cancer. J Clin Invest. 2019;130: pubmed publisher
  18. Araiz C, Yan A, Bettedi L, Samuelson I, Virtue S, McGavigan A, et al. Enhanced β-adrenergic signalling underlies an age-dependent beneficial metabolic effect of PI3K p110α inactivation in adipose tissue. Nat Commun. 2019;10:1546 pubmed publisher
  19. Ng P, Li J, Jeong K, Shao S, Chen H, Tsang Y, et al. Systematic Functional Annotation of Somatic Mutations in Cancer. Cancer Cell. 2018;33:450-462.e10 pubmed publisher
  20. Nan H, Han L, Ma J, Yang C, Su R, He J. STX3 represses the stability of the tumor suppressor PTEN to activate the PI3K-Akt-mTOR signaling and promotes the growth of breast cancer cells. Biochim Biophys Acta Mol Basis Dis. 2018;1864:1684-1692 pubmed publisher
  21. Simond A, Rao T, Zuo D, Zhao J, Muller W. ErbB2-positive mammary tumors can escape PI3K-p110α loss through downregulation of the Pten tumor suppressor. Oncogene. 2017;36:6059-6066 pubmed publisher
  22. Carpenter V, Chen Y, Dolat L, Valdivia R. The Effector TepP Mediates Recruitment and Activation of Phosphoinositide 3-Kinase on Early Chlamydia trachomatis Vacuoles. mSphere. 2017;2: pubmed publisher
  23. Hu L, Liang S, Chen H, Lv T, Wu J, Chen D, et al. ΔNp63α is a common inhibitory target in oncogenic PI3K/Ras/Her2-induced cell motility and tumor metastasis. Proc Natl Acad Sci U S A. 2017;114:E3964-E3973 pubmed publisher
  24. Zhang X, Spiegelman N, Nelson O, Jing H, Lin H. SIRT6 regulates Ras-related protein R-Ras2 by lysine defatty-acylation. elife. 2017;6: pubmed publisher
  25. Liu S, Gao G, Yan D, Chen X, Yao X, Guo S, et al. Effects of miR-145-5p through NRAS on the cell proliferation, apoptosis, migration, and invasion in melanoma by inhibiting MAPK and PI3K/AKT pathways. Cancer Med. 2017;6:819-833 pubmed publisher
  26. Cherniack A, Shen H, Walter V, Stewart C, Murray B, Bowlby R, et al. Integrated Molecular Characterization of Uterine Carcinosarcoma. Cancer Cell. 2017;31:411-423 pubmed publisher
  27. Dong Q, Fu L, Zhao Y, Tan S, Wang E. Derlin-1 overexpression confers poor prognosis in muscle invasive bladder cancer and contributes to chemoresistance and invasion through PI3K/AKT and ERK/MMP signaling. Oncotarget. 2017;8:17059-17069 pubmed publisher
  28. Kang Y, Balter B, Csizmadia E, Haas B, Sharma H, Bronson R, et al. Contribution of classical end-joining to PTEN inactivation in p53-mediated glioblastoma formation and drug-resistant survival. Nat Commun. 2017;8:14013 pubmed publisher
  29. Yang J, Savvatis K, Kang J, Fan P, Zhong H, Schwartz K, et al. Targeting LOXL2 for cardiac interstitial fibrosis and heart failure treatment. Nat Commun. 2016;7:13710 pubmed publisher
  30. Karki R, Man S, Malireddi R, Kesavardhana S, Zhu Q, Burton A, et al. NLRC3 is an inhibitory sensor of PI3K-mTOR pathways in cancer. Nature. 2016;540:583-587 pubmed publisher
  31. Bhagirath D, Zhao X, Mirza S, West W, Band H, Band V. Mutant PIK3CA Induces EMT in a Cell Type Specific Manner. PLoS ONE. 2016;11:e0167064 pubmed publisher
  32. Sikander M, Hafeez B, Malik S, Alsayari A, Halaweish F, Yallapu M, et al. Cucurbitacin D exhibits potent anti-cancer activity in cervical cancer. Sci Rep. 2016;6:36594 pubmed publisher
  33. Sheen M, Marotti J, Allegrezza M, Rutkowski M, Conejo Garcia J, Fiering S. Constitutively activated PI3K accelerates tumor initiation and modifies histopathology of breast cancer. Oncogenesis. 2016;5:e267 pubmed publisher
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