This is a Validated Antibody Database (VAD) review about bovine MAPT, based on 206 published articles (read how Labome selects the articles), using MAPT antibody in all methods. It is aimed to help Labome visitors find the most suited MAPT antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
MAPT synonym: tau
Knockout validation
| Invitrogen mouse monoclonal (Tau-5) |
| Invitrogen MAPT antibody (Thermo Scientific, MA5-12808) was used in western blot on human samples at 1:500 (fig 2) and in western blot knockout validation on mouse samples at 1:500 (fig 2). Int J Mol Sci (2022) ncbi |
| Invitrogen mouse monoclonal (HT7) |
| In order to validate antibodies against tau protein and its variants, Invitrogen MAPT antibody (Thermo Fisher, MN1000) was used in western blot on mouse samples , in western blot knockout validation on human samples at 1:1000 (tbl 1) and in immunocytochemistry on human samples at 1:100 (tbl 2). Mol Neurodegener (2017) ncbi |
| Invitrogen mouse monoclonal (BT2) |
| In order to validate antibodies against tau protein and its variants, Invitrogen MAPT antibody (Thermo Fisher, MN1010) was used in western blot on mouse samples , in western blot knockout validation on human samples at 1:1000 (tbl 1) and in immunocytochemistry on human samples at 1:100 (tbl 2). Mol Neurodegener (2017) ncbi |
| Invitrogen mouse monoclonal (T46) |
| In order to show that the tau family members MAP2 and MAP4 are subject to reversible acetylation, Invitrogen MAPT antibody (Thermofisher, T46) was used in western blot knockout validation on mouse samples at 1:1000 (fig 1b). PLoS ONE (2016) ncbi |
| Invitrogen mouse monoclonal (Tau-5) |
| In order to find no functional or morphological deficits upon tau reduction or depletion in aged mice, Invitrogen MAPT antibody (Invitrogen, AHB0042) was used in western blot knockout validation on mouse samples at 1:1000 (fig 4b). PLoS ONE (2016) ncbi |
| Invitrogen mouse monoclonal (Tau-5) |
| In order to suggest that Tau regulates neuronal pericentromeric heterochromatin integrity, Invitrogen MAPT antibody (Biosource, AHB0042) was used in immunocytochemistry knockout validation on mouse samples (fig 3) and in immunocytochemistry on human samples (fig 3). Sci Rep (2016) ncbi |
| Invitrogen mouse monoclonal (HT7) |
| In order to characterize nuclear indentations that are tau-positive in P301S tauopathy mice, Invitrogen MAPT antibody (Thermo Scientific, MN1000) was used in immunohistochemistry knockout validation on human samples (fig 2) and in immunohistochemistry - paraffin section on human samples (fig 2). Brain Pathol (2017) ncbi |
| Abcam mouse monoclonal (Tau-5) |
| In order to validate antibodies against tau protein and its variants, Abcam MAPT antibody (Abcam, Tau5) was used in western blot on mouse samples , in western blot knockout validation on human samples at 1:1000 (tbl 1) and in immunocytochemistry on human samples at 1:50 (tbl 2). Mol Neurodegener (2017) ncbi |
| MilliporeSigma mouse monoclonal (Tau46) |
| MilliporeSigma MAPT antibody (Sigma Aldrich, T9450) was used in western blot knockout validation on mouse samples at 1:500 (fig 1b). Neuroscience (2016) ncbi |
Invitrogen
| mouse monoclonal (Tau-5) |
| Invitrogen MAPT antibody (Thermo Scientific, AHB0042) was used in immunocytochemistry on mouse samples at 1:500 (fig 1a), in immunocytochemistry on human samples at 1:200 (fig 3e) and in western blot on human samples at 1:1000 (fig s2). Mol Ther Nucleic Acids (2022) ncbi |
| mouse monoclonal (HT7) |
| Invitrogen MAPT antibody (Thermo Fisher, MN1000B) was used in other on human samples (fig 3c) and in western blot on human samples at 1:20,000 (fig s9). ACS Chem Neurosci (2022) ncbi |
| mouse monoclonal (HT7) |
| Invitrogen MAPT antibody (Thermo Fisher, MN1000) was used in western blot on human samples (fig 1i, s2c). EBioMedicine (2022) ncbi |
| mouse monoclonal (Tau-5) |
| Invitrogen MAPT antibody (Thermo Scientific, MA5-12808) was used in western blot on human samples at 1:500 (fig 2) and in western blot knockout validation on mouse samples at 1:500 (fig 2). Int J Mol Sci (2022) ncbi |
| mouse monoclonal (Tau-5) |
| Invitrogen MAPT antibody (Thermo Fisher, MA5-12808) was used in western blot on human samples (fig s5f). Nat Commun (2021) ncbi |
| mouse monoclonal (HT7) |
| Invitrogen MAPT antibody (Thermo, MN1000) was used in western blot on mouse samples (fig 1a). Clin Transl Med (2021) ncbi |
| mouse monoclonal (Tau-5) |
| Invitrogen MAPT antibody (Invitrogen, AHB0042) was used in western blot on rat samples at 1:500 (fig 2f). Life Sci Alliance (2021) ncbi |
| mouse monoclonal (T46) |
| Invitrogen MAPT antibody (Invitrogen, 13-6400) was used in western blot on fruit fly |
| mouse monoclonal (Tau-5) |
| Invitrogen MAPT antibody (Thermo, MA5-12805) was used in western blot on rat samples at 1:1000 (fig 5a). elife (2021) ncbi |
| mouse monoclonal (T46) |
| Invitrogen MAPT antibody (Thermo Fisher Scientific, 13-6400) was used in western blot on mouse samples (fig 4a). Cell (2021) ncbi |
| mouse monoclonal (Tau-5) |
| Invitrogen MAPT antibody (Invitrogen, AHB0042) was used in immunocytochemistry on human samples at 0.5 ug/ml (fig 6d). Acta Neuropathol (2021) ncbi |
| mouse monoclonal (HT7) |
| Invitrogen MAPT antibody (Thermo Scientific, MN1000B) was used in immunohistochemistry - free floating section on human samples (fig 1). Sci Rep (2021) ncbi |
| mouse monoclonal (HT7) |
| Invitrogen MAPT antibody (Thermo Fischer, MN1000) was used in immunohistochemistry - free floating section on human samples (fig 3e). iScience (2021) ncbi |
| mouse monoclonal (Tau-5) |
| Invitrogen MAPT antibody (Thermo Fisher, AHB0042) was used in immunocytochemistry on mouse samples at 1:200 (fig 1a). Nat Commun (2021) ncbi |
| mouse monoclonal (HT7) |
| Invitrogen MAPT antibody (Invitrogen, MN1000) was used in western blot on human samples (fig 3f). Acta Neuropathol Commun (2020) ncbi |
| mouse monoclonal (HT7) |
| Invitrogen MAPT antibody (Invitrogen, MN1000) was used in immunohistochemistry on mouse samples at 1:500 (fig 2g). Acta Neuropathol Commun (2020) ncbi |
| mouse monoclonal (Tau-5) |
| Invitrogen MAPT antibody (Invitrogen, AHB0042) was used in western blot on human samples at 1:1000 (fig 2a). Nat Commun (2020) ncbi |
| mouse monoclonal (Tau-5) |
| Invitrogen MAPT antibody (Invitrogen, AHB0042) was used in immunohistochemistry on mouse samples (fig 3a). iScience (2020) ncbi |
| mouse monoclonal (HT7) |
| Invitrogen MAPT antibody (Invitrogen, MN1000) was used in immunoprecipitation on human samples at 1 ug/ml (fig 1a). Commun Biol (2020) ncbi |
| mouse monoclonal (HT7) |
| Invitrogen MAPT antibody (Thermo Fisher, MN1000) was used in western blot on human samples at 1:2000 (fig 4j). J Neuroinflammation (2020) ncbi |
| mouse monoclonal (HT7) |
| Invitrogen MAPT antibody (Thermo Fisher Scientific, MN1000) was used in immunohistochemistry - paraffin section on mouse samples at 1:500 (fig 4m) and in western blot on mouse samples at 1:1000 (fig 4k). Aging Cell (2020) ncbi |
| mouse monoclonal (HT7) |
| Invitrogen MAPT antibody (Thermo Fisher, MN1000) was used in immunohistochemistry on human samples at 1:500 (fig 3a). Biosci Rep (2020) ncbi |
| mouse monoclonal (HT7) |
| Invitrogen MAPT antibody (Thermo, MN1000) was used in western blot on mouse samples (fig 4a). Mol Neurodegener (2020) ncbi |
| mouse monoclonal (HT7) |
| Invitrogen MAPT antibody (ThermoFisher Scientific, MN1000) was used in immunohistochemistry on human samples at 1:50 (fig 5) and in western blot on human samples at 1:200-1:2000 (fig 5, 6). Nat Commun (2020) ncbi |
| mouse monoclonal (HT7) |
| Invitrogen MAPT antibody (Thermo Scientific,, MN1000) was used in immunohistochemistry on mouse samples at 1:500 (fig 1, 2, 4, 5, 6, 7, 8). Nat Commun (2020) ncbi |
| mouse monoclonal (BT2) |
| Invitrogen MAPT antibody (Thermo Fisher, MN1010) was used in ELISA on human samples (fig 5a). Acta Neuropathol Commun (2019) ncbi |
| mouse monoclonal (HT7) |
| Invitrogen MAPT antibody (Thermo Fisher, MN1000) was used in ELISA on human samples (fig 5a). Acta Neuropathol Commun (2019) ncbi |
| mouse monoclonal (Tau-5) |
| Invitrogen MAPT antibody (Thermo Fisher, MA5-12808) was used in western blot on mouse samples at 1:500 (fig s6e). Nature (2019) ncbi |
| mouse monoclonal (HT7) |
| Invitrogen MAPT antibody (Thermo Fisher, MN1000) was used in western blot on human samples at 1:1000 (fig 1m, 2f). Aging Cell (2020) ncbi |
| mouse monoclonal (HT7) |
| Invitrogen MAPT antibody (Invitrogen, MN1000) was used in immunohistochemistry on rat samples at 1:500 (fig 1d1). Alzheimers Res Ther (2019) ncbi |
| mouse monoclonal (HT7) |
| Invitrogen MAPT antibody (Thermo Fisher, MN1000) was used in western blot on rhesus macaque samples at 1:1000 (fig 4b). Aging Cell (2019) ncbi |
| mouse monoclonal (Tau-5) |
| Invitrogen MAPT antibody (Invitrogen, AHB0042) was used in western blot on human samples at 1:1000. elife (2019) ncbi |
| mouse monoclonal (Tau-5) |
| Invitrogen MAPT antibody (Invitrogen, AHB0042) was used in immunohistochemistry on mouse samples (fig 1c). Cell Rep (2018) ncbi |
| mouse monoclonal (HT7) |
| Invitrogen MAPT antibody (Thermo Fisher Scientific, HT7) was used in immunohistochemistry - frozen section on mouse samples (fig 2a). Neurobiol Aging (2018) ncbi |
| mouse monoclonal (HT7) |
| Invitrogen MAPT antibody (Thermo Fisher Scientific, HT7) was used in immunohistochemistry - free floating section on mouse samples at 1:1000 (fig 1a) and in western blot on mouse samples at 1:1000 (fig 5g). Aging Cell (2018) ncbi |
| mouse monoclonal (Tau-5) |
| Invitrogen MAPT antibody (Thermo Fisher, AHB0042) was used in western blot on mouse samples at 1:1000 (fig 8b). Cancer Res (2018) ncbi |
| mouse monoclonal (HT7) |
| Invitrogen MAPT antibody (Thermo Fisher, MN1000) was used in western blot on mouse samples (fig 4). Proc Natl Acad Sci U S A (2018) ncbi |
| mouse monoclonal (HT7) |
| In order to validate antibodies against tau protein and its variants, Invitrogen MAPT antibody (Thermo Fisher, MN1000) was used in western blot on mouse samples , in western blot knockout validation on human samples at 1:1000 (tbl 1) and in immunocytochemistry on human samples at 1:100 (tbl 2). Mol Neurodegener (2017) ncbi |
| mouse monoclonal (BT2) |
| In order to validate antibodies against tau protein and its variants, Invitrogen MAPT antibody (Thermo Fisher, MN1010) was used in western blot on mouse samples , in western blot knockout validation on human samples at 1:1000 (tbl 1) and in immunocytochemistry on human samples at 1:100 (tbl 2). Mol Neurodegener (2017) ncbi |
| mouse monoclonal (Tau-5) |
| In order to study the involvement of deacetylase HDAC6 in Tau pathology, Invitrogen MAPT antibody (Invitrogen, AHB0042) was used in immunocytochemistry on human samples at 1:500 (fig 1a). Cell Rep (2017) ncbi |
| mouse monoclonal (HT7) |
| In order to analyze the effects of a panel of anti-tau antibodies on neuronal uptake and aggregation of tau, Invitrogen MAPT antibody (Thermo Fisher, HT7) was used in ELISA on mouse samples (fig 2a). Am J Pathol (2017) ncbi |
| mouse monoclonal (HT7) |
| In order to show that ALOX5 upregulation results in homocysteine-dependent worsening of the Alzheimer's disease phenotype, Invitrogen MAPT antibody (Thermo, MN1000) was used in immunohistochemistry on mouse samples (fig 4c) and in western blot on mouse samples (fig 4a). Sci Rep (2017) ncbi |
| mouse monoclonal (Tau-5) |
| In order to elucidate how liraglutide affects disease and cognitive function in a mouse model of Alzheimer disease, Invitrogen MAPT antibody (Invitrogen, AHB0042) was used in western blot on mouse samples at 1:1000 (fig 2A). Neurochem Res (2017) ncbi |
| mouse monoclonal (Tau-5) |
| In order to assess the role of MECP2 in tau pathology using several mouse models, Invitrogen MAPT antibody (Thermo Fisher Scientific, AHB0042) was used in western blot on mouse samples (fig 5a). Front Mol Neurosci (2017) ncbi |
| mouse monoclonal (Tau-5) |
| In order to evaluate the efficacy of an orally bioactive and brain permeable gamma-secretase inhibitor in a mouse model of Alzheimer's disease, Invitrogen MAPT antibody (Thermo, MA5-12805) was used in western blot on mouse samples at 1:1000 (fig 4b). Nat Commun (2017) ncbi |
| mouse monoclonal (HT7) |
| In order to evaluate the efficacy of an orally bioactive and brain permeable gamma-secretase inhibitor in a mouse model of Alzheimer's disease, Invitrogen MAPT antibody (Thermo, MN1000) was used in western blot on human samples at 1:1000 (fig 3i). Nat Commun (2017) ncbi |
| mouse monoclonal (BT2) |
| In order to examine tau distribution and release using organotypic brain slice cultures, Invitrogen MAPT antibody (Fisher Scientific, MN1010) was used in ELISA on mouse samples (fig 4a). Cell Death Dis (2017) ncbi |
| mouse monoclonal (T46) |
| In order to study the mechanisms of pathogenesis via tau acetylation in Alzheimer's disease, Invitrogen MAPT antibody (Thermo Fisher, 13-6400) was used in immunoprecipitation on human samples and in western blot on human samples at 1:1000 (fig 1b). Sci Rep (2017) ncbi |
| mouse monoclonal (Tau-5) |
| In order to investigate the expression patterns of HA synthases in the murine central nervous system, Invitrogen MAPT antibody (Life Technologies, AHB0042) was used in immunohistochemistry - frozen section on mouse samples at 1:100 (fig 2e). J Alzheimers Dis (2017) ncbi |
| mouse monoclonal (HT7) |
| In order to generate and characterize a new mouse model of Alzheimer's disease, Invitrogen MAPT antibody (Thermo Scientific, MN1000) was used in western blot on human samples at 0.2 ug/ml (fig 1b). Aging Cell (2017) ncbi |
| mouse monoclonal (Tau-5) |
| In order to report that docosahexaenoic acid is an inducer of cellular protein aggregates, Invitrogen MAPT antibody (Invitrogen, AHB0042) was used in western blot on mouse samples at 1:5000 (fig 4b). Exp Mol Med (2017) ncbi |
| mouse monoclonal (Tau-5) |
| In order to see that the granulin Alzheimer's disease risk variant has no significant effects on florbetapir positron emission tomographic amyloid imaging and cerebrospinal fluid Abeta levels, Invitrogen MAPT antibody (Thermo Fisher, AHB0042) was used in western blot on human samples at 1:2000 (fig 7a). Acta Neuropathol (2017) ncbi |
| mouse monoclonal (HT7) |
| In order to investigate how TRIM21 neutralizes tau seeds, Invitrogen MAPT antibody (Thermo Fisher, MN1000) was used in immunocytochemistry on human samples (fig s2a) and in western blot on human samples (fig s1). Proc Natl Acad Sci U S A (2017) ncbi |
| mouse monoclonal (T46) |
| In order to show that the tau family members MAP2 and MAP4 are subject to reversible acetylation, Invitrogen MAPT antibody (Thermofisher, T46) was used in western blot knockout validation on mouse samples at 1:1000 (fig 1b). PLoS ONE (2016) ncbi |
| mouse monoclonal (HT7) |
| In order to use direct intrahippocampal administration of the adeno-associated virus-vectored anti-phospho-tau antibody to reduce disease, Invitrogen MAPT antibody (Life Technologies, MN 1000B) was used in ELISA on human samples . J Neurosci (2016) ncbi |
| mouse monoclonal (T46) |
| In order to report the effects of okadaic acid-induced tau hyperphosphorylation on secreted and cellular levels of brain-derived neurotrophic factor in primary cortical neurons, Invitrogen MAPT antibody (Thermofisher, 13-6400) was used in immunocytochemistry on rat samples at 1:100 (fig 4b). J Chem Neuroanat (2017) ncbi |
| mouse monoclonal (T46) |
| In order to discuss the contribution of leucine-rich repeat kinase 2 mutations to Parkinson's disease, Invitrogen MAPT antibody (Invitrogen, 136400) was used in immunocytochemistry on human samples at 1:200 (fig 2c) and in western blot on human samples at 1:1000 (fig 2e). J Neuroinflammation (2016) ncbi |
| mouse monoclonal (HT7) |
| In order to explore the role of hippocampal T cell infiltration in tau-driven pathophysiology and cognitive impairments, Invitrogen MAPT antibody (Thermo Scientific, MN1000) was used in western blot on mouse samples . Brain (2017) ncbi |
| mouse monoclonal (Tau-5) |
| In order to find no functional or morphological deficits upon tau reduction or depletion in aged mice, Invitrogen MAPT antibody (Invitrogen, AHB0042) was used in western blot knockout validation on mouse samples at 1:1000 (fig 4b). PLoS ONE (2016) ncbi |
| mouse monoclonal (Tau-5) |
| In order to study the role of SNARE machinery in neuronal polarity and selective protein targeting, Invitrogen MAPT antibody (Invitrogen, Tau-5) was used in immunocytochemistry on rat samples at 1:1000 (fig s1a). PLoS ONE (2016) ncbi |
| mouse monoclonal (HT7) |
| In order to test if alpha-synuclein preformed fibrils alter endothelial function, Invitrogen MAPT antibody (Thermo Scientific, MN1000) was used in immunocytochemistry on human samples at 1:1000 (fig 3d). Exp Neurol (2016) ncbi |
| mouse monoclonal (Tau-5) |
| In order to suggest that Tau regulates neuronal pericentromeric heterochromatin integrity, Invitrogen MAPT antibody (Biosource, AHB0042) was used in immunocytochemistry knockout validation on mouse samples (fig 3) and in immunocytochemistry on human samples (fig 3). Sci Rep (2016) ncbi |
| mouse monoclonal (Tau-5) |
| In order to examine S-guanylation of tau and report its effects on tau aggregation, Invitrogen MAPT antibody (Invitrogen, AHB0042) was used in western blot on human samples (fig 3d). J Biol Chem (2016) ncbi |
| mouse monoclonal (HT7) |
| In order to examine S-guanylation of tau and report its effects on tau aggregation, Invitrogen MAPT antibody (Thermo Scientific, MN1000) was used in western blot on human samples (fig 1a). J Biol Chem (2016) ncbi |
| mouse monoclonal (S.125.0) |
| In order to investigate 20nm citrate-coated and polyvinylpyrrolidone-coated silver nanoparticle-induced neurotoxicity, Invitrogen MAPT antibody (Pierce, MA5-15108) was used in immunocytochemistry on human samples at 1:300 (fig 5b). Neurotoxicology (2016) ncbi |
| mouse monoclonal (HT7) |
| In order to characterize an Alzheimer's disease model that utilizes Octodon degus, Invitrogen MAPT antibody (Thermo Fisher, MN1000) was used in western blot on rat samples at 1:1000 (fig 7). Acta Neuropathol Commun (2016) ncbi |
| mouse monoclonal (S.125.0) |
| In order to describe a role for HMGB1 in Alzheimer's disease pathogenesis, Invitrogen MAPT antibody (Thermo Fisher, MA5-15108) was used in immunohistochemistry - paraffin section on human samples at 1:2000 (fig 2d). Sci Rep (2016) ncbi |
| mouse monoclonal (HT7) |
| In order to discuss the contribution of 12/15-lipoxygenase to Alzheimer's disease, Invitrogen MAPT antibody (Thermo Scientific, HT7) was used in immunohistochemistry on mouse samples at 1:300 (fig 3c) and in western blot on mouse samples at 1:200 (fig 3a). Biol Psychiatry (2017) ncbi |
| mouse monoclonal (HT7) |
| In order to identify and characterize a DYRK1A inhibitor, Invitrogen MAPT antibody (Thermo Scientific, MN1000) was used in western blot on human samples at 1:1000 (fig 3). Dis Model Mech (2016) ncbi |
| mouse monoclonal (HT7) |
| In order to test if antibody effector function is required for limiting the spread of tau, Invitrogen MAPT antibody (Thermo Scientific, MN1000) was used in immunohistochemistry - paraffin section on human samples at 1:1000 (fig 1a), in immunocytochemistry on human samples (fig 4b) and in western blot on human samples (fig 1c). Cell Rep (2016) ncbi |
| mouse monoclonal (HT7) |
| In order to identify NFE2L2/NRF2 as a regulator of autophagy gene expression and study its role in Alzheimer disease, Invitrogen MAPT antibody (Thermo Scientific, MN1000B) was used in immunohistochemistry - free floating section on mouse samples at 1:250 (fig 5a), in immunohistochemistry - paraffin section on mouse samples at 1:250 (fig 5a) and in western blot on mouse samples at 1:2000 (fig 5b). Autophagy (2016) ncbi |
| mouse monoclonal (HT7) |
| In order to study a novel therapeutic strategy for Alzheimer's disease via Pim1 inhibition, Invitrogen MAPT antibody (Thermo Fisher, MN1000) was used in western blot on mouse samples at 1:3000 (fig 6). Mol Neurodegener (2016) ncbi |
| mouse monoclonal (Tau-5) |
| In order to investigate the axon initial segment in neurological disorders, Invitrogen MAPT antibody (Life Technologies, AHB0042) was used in western blot on human samples (fig s3). Mol Neurodegener (2016) ncbi |
| mouse monoclonal (HT7) |
| In order to investigate the axon initial segment in neurological disorders, Invitrogen MAPT antibody (Thermo Scientific, MN1000) was used in western blot on human samples (fig 2). Mol Neurodegener (2016) ncbi |
| mouse monoclonal (HT7) |
| In order to assess the accumulation in the cerebrospinal fluid of seed-competent HMW tau specis in an Alzheimer's disease mouse model and in human patients, Invitrogen MAPT antibody (Thermo Scientific, MN1000) was used in blocking or activating experiments on human samples (fig 3). Ann Neurol (2016) ncbi |
| mouse monoclonal (HT7) |
| In order to characterize nuclear indentations that are tau-positive in P301S tauopathy mice, Invitrogen MAPT antibody (Thermo Scientific, MN1000) was used in immunohistochemistry knockout validation on human samples (fig 2) and in immunohistochemistry - paraffin section on human samples (fig 2). Brain Pathol (2017) ncbi |
| mouse monoclonal (HT7) |
| In order to assess induction of synaptic impairment and memory deficit by calcieurin-mediated inactivation of nuclear CaMKIV/CREB signaling due to tau accumulation, Invitrogen MAPT antibody (Thermo Fisher, MN1000) was used in western blot on human samples at 1:1000 (fig 1). Proc Natl Acad Sci U S A (2016) ncbi |
| mouse monoclonal (HT7) |
| In order to assess induction of degradation of nicotinic acetylcholine receptor alpha4 via activating calpain-2 due to accumulation of human full-length tau, Invitrogen MAPT antibody (Thermo Fisher, MN1000) was used in western blot on rat samples at 1:1000 (fig 1). Sci Rep (2016) ncbi |
| mouse monoclonal (HT7) |
| In order to study alteration of MAP2 splicing in Huntington's disease, Invitrogen MAPT antibody (Thermo Fisher, MN1000) was used in immunohistochemistry - paraffin section on human samples at 1:100 (fig 5). Brain Pathol (2017) ncbi |
| mouse monoclonal (Tau-5) |
| In order to determine modulation of cellular release of tau by FRMD4A-cytohesin signaling, Invitrogen MAPT antibody (Invitrogen, AHB0042) was used in immunocytochemistry on human samples at 1:600 (fig 4) and in western blot on human samples at 1:1000 (fig 2). J Cell Sci (2016) ncbi |
| mouse monoclonal (Tau-5) |
| In order to utilize a time course study of sciatic nerves from aging mice to gain a neurogenic perspective of sarcopenia, Invitrogen MAPT antibody (Biosource International, AHB0042) was used in immunohistochemistry - frozen section on mouse samples at 1:500 (tbl 1) and in western blot on mouse samples at 1:500 (tbl 1). J Neuropathol Exp Neurol (2016) ncbi |
| mouse monoclonal (Tau-5) |
| In order to study enhanced degradation of proteasomal substrates that are associated with neurodegenerative disease and the effect of inactivation of USP14, Invitrogen MAPT antibody (Invitrogen, AHB0042) was used in western blot on human samples (fig 2). F1000Res (2016) ncbi |
| mouse monoclonal (Tau-5) |
| In order to investigate the role of channel gating in mammalian proteasomes, Invitrogen MAPT antibody (Invitrogen, Tau-5) was used in western blot on human samples at 1:10,000 (fig 3f). Nat Commun (2016) ncbi |
| mouse monoclonal (HT7) |
| In order to elucidate the exacerbation of human Tau neurotoxicity in vivo by acetylation mimic of lysine 280, Invitrogen MAPT antibody (Thermo Scientific, HT7) was used in western blot on human samples at 1:2000 (fig 4). Sci Rep (2016) ncbi |
| mouse monoclonal (HT7) |
| In order to study the inner circular smooth muscle of the developing mouse intestine transcriptome: evidence that the hedgehog target gene, cJun, regulates visceral smooth muscle genes, Invitrogen MAPT antibody (Thermo Scientific, MN1000) was used in western blot on human samples at 1:2000 (fig 1). Dev Dyn (2016) ncbi |
| mouse monoclonal (Tau-5) |
| In order to investigate survival and neuronal differentiation of human BM-MSCs by pulsed electromagnetic fields, Invitrogen MAPT antibody (Invitrogen, AHB0042) was used in western blot on human samples (fig 1). Life Sci (2016) ncbi |
| mouse monoclonal (HT7) |
| In order to elucidate a mouse model of frontotemporal dementia by decreased social exploration, impulsivity, and executive dysfunction, Invitrogen MAPT antibody (Thermo Scientifi, HT7) was used in immunohistochemistry - paraffin section on mouse samples at 1:500 (fig 1). Neurobiol Learn Mem (2016) ncbi |
| mouse monoclonal (T46) |
| In order to assess rescue of Alzheimer's disease in the mouse by improved proteostasis in the secretory pathway, Invitrogen MAPT antibody (Invitrogen, T46) was used in western blot on mouse samples at 1:1000 (fig 7). Brain (2016) ncbi |
| mouse monoclonal (Tau-5) |
| In order to study reduction of hyperphosphorilated Tau by beta-secretase 1's targeting implying autophagy actors in 3xTg-AD mice, Invitrogen MAPT antibody (Thermo Fisher, TAU-5) was used in western blot on mouse samples at 1:1000 (tbl 1) and in western blot on human samples at 1:1000 (tbl 1). Front Cell Neurosci (2015) ncbi |
| mouse monoclonal (HT7) |
| In order to study the Alzheimer's disease brain for a decrease in HNK-1 carrier glycoproteins, Invitrogen MAPT antibody (ThermoFisher, HT7) was used in western blot on human samples (fig s2). Mol Neurobiol (2017) ncbi |
| mouse monoclonal (HT7) |
| In order to characterize tau pathology mouse models via obesity, diabetes, and leptin resistance, Invitrogen MAPT antibody (Pierce, HT7) was used in western blot on mouse samples at 1:1000 (fig 1). Neuroscience (2016) ncbi |
| mouse monoclonal (Tau-5) |
| In order to survey the activation of a synapse weakening pathway by human Val66, not Met66 in proBDNF, Invitrogen MAPT antibody (Invitrogen, AHB0042) was used in western blot on human samples (fig 3). Pharmacol Res (2016) ncbi |
| mouse monoclonal (HT7) |
| In order to assess the impairment in synaptic plasticity and learning due to amyloid-beta dimers in the absence of plaque pathology, Invitrogen MAPT antibody (Thermo Scientific, MN1000) was used in western blot on mouse samples at 1:1000 (fig 3). Brain (2016) ncbi |
| mouse monoclonal (Tau-5) |
| In order to study Alzheimer's disease by use of a domestic cat animal model, Invitrogen MAPT antibody (Life Technologies, TAU-5) was used in western blot on cat samples at 1:1000 (fig 4). Acta Neuropathol Commun (2015) ncbi |
| mouse monoclonal (Tau-5) |
| In order to assess the deletion of Ccr2 and cavity size and tau pathology after mild traumatic brain injury, Invitrogen MAPT antibody (Invitrogen, ahb0042) was used in western blot on mouse samples at 1:5000 (fig 5). J Neuroinflammation (2015) ncbi |
| mouse monoclonal (Tau-5) |
| In order to characterize chronic traumatic encephalopathy to determine if phosphorylated tau is unique in epileptic brain and chronic traumatic encephalopathy, Invitrogen MAPT antibody (Life Technologies, AHB0042) was used in western blot on human samples at 1,000 ug/ml (fig 10). Brain Res (2016) ncbi |
| mouse monoclonal (T46) |
| In order to assess using the biochemical properties of tau to classify tauopathies, Invitrogen MAPT antibody (Thermo Scientific, T46) was used in immunohistochemistry on human samples at 1:500 (fig 6) and in western blot on human samples (fig 2). Acta Neuropathol (2016) ncbi |
| mouse monoclonal (HT7) |
| In order to investigate Alzheimer's Disease in a mouse model where ribosomal protein S6 kinase is decreased, Invitrogen MAPT antibody (Thermo Fisher Scientific, MN1000) was used in western blot on human samples at 1:3000 (fig 5). J Neurosci (2015) ncbi |
| mouse monoclonal (HT7) |
| In order to report that the di-phenyl-pyrazole anle138b binds to and inhibits tau aggregation in vitro and in vivo, Invitrogen MAPT antibody (ThermoScientific, HT7) was used in western blot on human samples at 1:5000 (fig 3). Acta Neuropathol (2015) ncbi |
| mouse monoclonal (HT7) |
| In order to investigate how tau propagation is interrupted due to microglia depletion and exosome synthesis inhibition, Invitrogen MAPT antibody (Thermo Fisher Scientific, MN1000) was used in immunohistochemistry on mouse samples at 1:500 (fig 1) and in western blot on mouse samples at 1:500 (fig 5). Nat Neurosci (2015) ncbi |
| mouse monoclonal (HT7) |
| In order to investigate the effects of tau acetylation at Lys174, Invitrogen MAPT antibody (Thermo Scientific, MN1000) was used in immunohistochemistry - free floating section on mouse samples (fig 2). Nat Med (2015) ncbi |
| mouse monoclonal (Tau-5) |
| In order to investigate the effects of tau acetylation at Lys174, Invitrogen MAPT antibody (Life Technologies, AHB0042) was used in immunoprecipitation on human samples (fig 1) and in western blot on human samples (fig 1). Nat Med (2015) ncbi |
| mouse monoclonal (Tau-5) |
| In order to test if BAG2 mediates the cold-induced accumulation of phosphorylated tau protein, Invitrogen MAPT antibody (Life Technologies, AHB0042) was used in western blot on human samples . Cell Mol Neurobiol (2016) ncbi |
| mouse monoclonal (Tau-5) |
| In order to investigate the involvement of microRNA-195 in the effect of chronic brain hypoperfusion on rodent Cdk5/p25 and tau phosphorylation, Invitrogen MAPT antibody (Invitrogen, AHB0042) was used in western blot on rat samples at 1:1000. J Neurochem (2015) ncbi |
| mouse monoclonal (HT7) |
| In order to study amelioration of tau pathology and cognition in the offspring of triple transgenic AD mice by maternal dexamethasone exposure, Invitrogen MAPT antibody (Thermo, HT-7) was used in western blot on mouse samples at 1:200 (fig 3). Mol Psychiatry (2016) ncbi |
| mouse monoclonal (HT7) |
| In order to characterize live neurons cultured from adult P301S tau mice by use of the fluorescent pentameric oligothiophene pFTAA that identifies filamentous tau, Invitrogen MAPT antibody (Thermo Scientific, MN1000) was used in immunocytochemistry on mouse samples at 1:500 (fig 1,2,3). Front Neurosci (2015) ncbi |
| mouse monoclonal (Tau-5) |
| In order to elucidate how methylene blue inhibits tau aggregation, Invitrogen MAPT antibody (Biosource, AHB0042) was used in western blot on human samples at 1:5000 (fig 1). Sci Rep (2015) ncbi |
| mouse monoclonal (HT7) |
| Invitrogen MAPT antibody (Thermo Scientific, HT7) was used in western blot on human samples at 1:3000. Mol Neurobiol (2016) ncbi |
| mouse monoclonal (Tau-5) |
| In order to test the effects of high fat diet using a mouse model of familial Alzheimer disease, Invitrogen MAPT antibody (Biosource, AHB0042) was used in western blot on mouse samples (fig 4). Biochim Biophys Acta (2015) ncbi |
| mouse monoclonal (Tau-5) |
| In order to investigate the role of Apaf1 in axonogenesis, Invitrogen MAPT antibody (Life Technologies, AHB0042) was used in western blot on human samples . Cell Mol Life Sci (2015) ncbi |
| mouse monoclonal (BT2) |
| Invitrogen MAPT antibody (Thermo Scientific, BT2) was used in ELISA on human samples . PLoS ONE (2015) ncbi |
| mouse monoclonal (HT7) |
| Invitrogen MAPT antibody (Thermo Scientific, HT7) was used in ELISA on human samples . PLoS ONE (2015) ncbi |
| mouse monoclonal (HT7) |
| In order to use rTg4510 mice to elucidate pathogenesis of tau-induced disease, Invitrogen MAPT antibody (Thermo Scientific, HT7) was used in western blot on human samples (fig 1a). Mol Neurodegener (2015) ncbi |
| mouse monoclonal (BT2) |
| In order to use rTg4510 mice to elucidate pathogenesis of tau-induced disease, Invitrogen MAPT antibody (Thermo Scientific, BT2) was used in ELISA on human samples (fig 7). Mol Neurodegener (2015) ncbi |
| mouse monoclonal (T46) |
| In order to identify small-molecules that inhibit the interaction between CDK5 and p25, Invitrogen MAPT antibody (Invitrogen, 13-6400) was used in western blot on human samples . Chem Biol (2015) ncbi |
| mouse monoclonal (T46) |
| In order to report a case of glial mixed tau and TDP-43 proteinopathies in a Japanese patient, Invitrogen MAPT antibody (Zymed, T46) was used in western blot on human samples at 1:1000. Brain Pathol (2016) ncbi |
| mouse monoclonal (HT7) |
| In order to investigate the cerebral delivery of small interfering RNAs targeting human tau, Invitrogen MAPT antibody (Thermo, MN1000) was used in western blot on mouse samples at 1:1000. Curr Gene Ther (2014) ncbi |
| mouse monoclonal (T46) |
| In order to characterize two mouse models overexpressing different human tau protein constructs, Invitrogen MAPT antibody (Invitrogen, 13-6400) was used in western blot on human samples (fig 1). Cell Mol Life Sci (2015) ncbi |
| mouse monoclonal (HT7) |
| In order to characterize the behavioral, biochemical, and neuropathologic effects of 8ISO in the triple transgenic mouse model of Alzheimer's disease, Invitrogen MAPT antibody (Thermo Scientific, MN1000) was used in immunohistochemistry - paraffin section on mouse samples at 1:100 and in western blot on mouse samples at 1:200. Neurobiol Aging (2015) ncbi |
| mouse monoclonal (HT7) |
| In order to determine whether there is a pathogenic interaction of the environmental toxin piericidin A from streptomyces spp. and the P301S mutation, Invitrogen MAPT antibody (Thermo Scientific Pierce, MN1000) was used in western blot on mouse samples at 1:1000. PLoS ONE (2014) ncbi |
| mouse monoclonal (Tau-5) |
| In order to evaluate motor function and tau pathology of P301S tau transgenic mice, Invitrogen MAPT antibody (Invitrogen, TAU5) was used in immunohistochemistry - paraffin section on human samples at 1:500 (fig 2) and in western blot on human samples at 1:1000 (fig 4). Mol Neurodegener (2014) ncbi |
| mouse monoclonal (HT7) |
| In order to investigate the interactions between Abeta1-42 and Abeta1-40, Invitrogen MAPT antibody (Pierce, MN1000) was used in western blot on mouse samples . Mol Neurodegener (2014) ncbi |
| mouse monoclonal (HT7) |
| In order to determine seeding potencies of recombinant and native Tau aggregates due to conformation, Invitrogen MAPT antibody (Thermo (Pierce), HT7) was used in immunocytochemistry on human samples at 1:500 (fig 6) and in western blot on human samples at 1:2500 (fig 4). J Biol Chem (2015) ncbi |
| mouse monoclonal (HT7) |
| In order to test if CHIP ameliorates the pathological changes associated with tau aggregation, Invitrogen MAPT antibody (Thermo, HT7) was used in immunocytochemistry on human samples at 1:1000 and in western blot on human samples at 1:5000. J Alzheimers Dis (2015) ncbi |
| mouse monoclonal (Tau-5) |
| In order to use triple transgenic Alzhemier's mice to study short- and long-term CDK5 knockdown and prevention of spatial memory dysfunction and tau pathology, Invitrogen MAPT antibody (Invitrogen, Tau5) was used in western blot on mouse samples (fig 2). Front Aging Neurosci (2014) ncbi |
| mouse monoclonal (Tau-5) |
| In order to investigate the role of membrane-anchored versus soluble CX3CL1 in regulating the microglia-mediated amelioration of Abeta pathology, Invitrogen MAPT antibody (Invitrogen, AHB0042) was used in western blot on mouse samples at 1:20,000. J Neurosci (2014) ncbi |
| mouse monoclonal (HT7) |
| In order to assess the effect of aging on brain lipoxin A4 levels using non-transgenic and 3xTg-AD mice, Invitrogen MAPT antibody (Thermo Scientific, HT7) was used in western blot on human samples (fig 4). J Alzheimers Dis (2015) ncbi |
| mouse monoclonal (HT7) |
| In order to study the relationship of an Alzheimer's disease-linked SNP in the CLU gene and Tau, Invitrogen MAPT antibody (Thermo Scientific Pierce, MN1000) was used in western blot on human samples . PLoS ONE (2014) ncbi |
| mouse monoclonal (Tau-5) |
| In order to assess if tau reduction benefits intractable genetic epilepsies, Invitrogen MAPT antibody (Life Technologies, tau-5) was used in immunohistochemistry on mouse samples at 1:3000. Ann Neurol (2014) ncbi |
| mouse monoclonal (HT7) |
| In order to investigate the role of tau missplicing in the pathogenesis of Huntington disease, Invitrogen MAPT antibody (Thermo Scientific, MN1000) was used in immunohistochemistry - paraffin section on human samples at 1:200. Nat Med (2014) ncbi |
| mouse monoclonal (Tau-5) |
| In order to investigate the abnormalites in hippocampal energy metabolism in the pathogenesis of Alzheimer disease, Invitrogen MAPT antibody (Biosource, AHB0042) was used in western blot on mouse samples . Biochim Biophys Acta (2014) ncbi |
| mouse monoclonal (HT7) |
| In order to study the role of exagerated Ca(2+) signaling mediated by InsP3 receptor1 in the pathogenesis of mutant presenilin-linked Alzheimer's disease, Invitrogen MAPT antibody (Thermo Scientific, HT7) was used in western blot on mouse samples at 1:500. J Neurosci (2014) ncbi |
| mouse monoclonal (HT7) |
| In order to study the lack of involvementof GSK3-alpha/beta in the elevated tau phosphorylation observed in Tau.P30L hypothermic mice, Invitrogen MAPT antibody (Thermo Scientific, MN1000) was used in western blot on human samples . Eur J Neurosci (2014) ncbi |
| mouse monoclonal (Tau-5) |
| In order to study how induction of Calyculin A in N2a cells can attenuate axonal transport impairment and axonopathy by Berberine, Invitrogen MAPT antibody (NeoMarkers, tau-5) was used in western blot on mouse samples at 1:500. PLoS ONE (2014) ncbi |
| mouse monoclonal (Tau-5) |
| In order to investigate the murine tau isoforms in brain and peripheral organs, Invitrogen MAPT antibody (Invitrogen, AHB0042) was used in western blot on mouse samples at 1:1000. PLoS ONE (2013) ncbi |
| mouse monoclonal (HT7) |
| In order to study the beneficial effects of increasing the O-GlucNAcylation of brain proteins on the survival and breathing of aged tau P301L transgenic mice, Invitrogen MAPT antibody (Thermo Scientific, HT7) was used in immunoprecipitation on mouse samples , in immunohistochemistry on mouse samples and in western blot on mouse samples . PLoS ONE (2013) ncbi |
| mouse monoclonal (Tau-5) |
| In order to identify a method for simultaneous use of both biochemistry and immunohistochemistry in regards to the same tissue, Invitrogen MAPT antibody (Thermo Fisher Scientific, Tau-5) was used in western blot on mouse samples at 1:4000. Eur J Neurosci (2014) ncbi |
| mouse monoclonal (HT7) |
| Invitrogen MAPT antibody (Thermo Fisher Scientific, HT7) was used in immunohistochemistry - free floating section on mouse samples and in western blot on mouse samples . Am J Pathol (2014) ncbi |
| mouse monoclonal (Tau-5) |
| In order to study the composition of pathological granules that appear in degenerative brain diseases, Invitrogen MAPT antibody (Biosource, AHB0042) was used in immunohistochemistry - frozen section on mouse samples . Age (Dordr) (2014) ncbi |
| mouse monoclonal (Tau-5) |
| In order to test if beta-amyloid accumulation affects prion infectivity and if different amounts of PrP affect beta-amyloid accumulation, Invitrogen MAPT antibody (Invitrogen, #AHB0042) was used in western blot on mouse samples (fig 6). Neurobiol Aging (2013) ncbi |
| mouse monoclonal (HT7) |
| In order to study the effects of a pathogenic tau fragment on hippocampal neurogenesis, behaviour and learning, Invitrogen MAPT antibody (Thermo-Fisher Pierce, MN-100) was used in immunohistochemistry - frozen section on mouse samples at 1:300, in immunocytochemistry on mouse samples at 1:300 and in immunohistochemistry on mouse samples at 1:300. Neurobiol Aging (2013) ncbi |
| mouse monoclonal (HT7) |
| In order to study the brain expression of a number of cell adhesion molecules in murine models of Alzheimer's disease, Invitrogen MAPT antibody (Thermo, MN1000) was used in immunohistochemistry on mouse samples . PLoS ONE (2013) ncbi |
| mouse monoclonal (Tau-5) |
| In order to study the ability of pharmacological activation of AMPK to protect a human neuroblastoma cell line against homocysteine-induced toxicity, Invitrogen MAPT antibody (Lab Vision, MS-247-P0) was used in western blot on human samples at 1:200 (fig 2). Neurochem Res (2013) ncbi |
| mouse monoclonal (Tau-5) |
| In order to study changes in autophagy and the roles of Tau hyperphosphorylation and fractalkine in an animal model of Abeta42-induced Tau hyperphosphorylation, Invitrogen MAPT antibody (Thermo Scientific, Tau-5) was used in western blot on rat samples at 1:1000, in immunohistochemistry on human samples at 1:1000 and in western blot on human samples at 1:1000 (fig 3). Exp Neurol (2014) ncbi |
| mouse monoclonal (HT7) |
| In order to study the association of GSK3 activity with tau phosphorylation and neuronal tyrosine phosphorylation in a murine model expressing human P301L tau, Invitrogen MAPT antibody (Thermo Scientific, HT7) was used in western blot on human samples at 1:40,000 and in western blot on mouse samples at 1:40,000 (tbl 1). Neurobiol Aging (2013) ncbi |
| mouse monoclonal (Tau-5) |
| In order to elucidate the role of dietary resveratrol in SAMP8 mice, Invitrogen MAPT antibody (BioSource, AHB0042) was used in western blot on mouse samples at 1:1000 (fig 6). Age (Dordr) (2013) ncbi |
| mouse monoclonal (HT7) |
| In order to study the tau-induced loss of synapses in a murine model overexpressing the P301L mutant tau, Invitrogen MAPT antibody (ThermoScientific, MN1000) was used in immunohistochemistry on mouse samples and in western blot on mouse samples . J Comp Neurol (2013) ncbi |
| mouse monoclonal (Tau-5) |
| In order to investigate the contribution of Ang II to Alzheimer disease, Invitrogen MAPT antibody (Invitrogen, Tau-5) was used in western blot on mouse samples (fig 3). FEBS Lett (2012) ncbi |
| mouse monoclonal (Tau-5) |
| In order to examine the brains of 6-month-old rats treated neonatally with the glutamatergic beta-N-methylamino-L-alanine, Invitrogen MAPT antibody (Invitrogen, AHB0042) was used in immunohistochemistry on rat samples at 1:2000. Toxicol Sci (2012) ncbi |
| mouse monoclonal (Tau-5) |
| In order to investigate interactions between MAP2 and PP2A/Balpha in the brain, Invitrogen MAPT antibody (BIOSOURCE, Tau-5) was used in western blot on mouse samples (fig 1). J Biol Chem (2012) ncbi |
| mouse monoclonal (HT7) |
| In order to examine the brains of non-demented high pathology controls individuals for mechanisms that protect against Alzheimer's disease, Invitrogen MAPT antibody (Pierce, MN1000) was used in western blot on human samples . PLoS ONE (2011) ncbi |
| mouse monoclonal (Tau-5) |
| In order to determine the distribution of tauopathy in different regions of the brain using the alpha-Syn overexpressing mouse model, Invitrogen MAPT antibody (Biosource, AHB0042) was used in immunohistochemistry on mouse samples (fig 3). BMC Neurosci (2011) ncbi |
| mouse monoclonal (Tau-5) |
| In order to test if neurite retraction in the SH-SY5Y model is associated with changes in other tau hyperphosphorylable residues, Invitrogen MAPT antibody (BioSource, AHB0042) was used in western blot on human samples at 1:1000 (fig 2). J Neurosci Res (2011) ncbi |
| mouse monoclonal (Tau-5) |
| In order to examine tauopathy in mice that overexpress human alpha-synuclein as a model of Parkinson's disease, Invitrogen MAPT antibody (Invitrogen, AHB0042) was used in western blot on human samples at 1:500 (fig 2). Eur J Neurosci (2011) ncbi |
| mouse monoclonal (Tau-5) |
| In order to study the tauopathic changes in the striatum of the alpha-synuclein A53T mutant mouse, Invitrogen MAPT antibody (Biosource, AHB0042) was used in western blot on mouse samples at 1:500 (fig 3). PLoS ONE (2011) ncbi |
| mouse monoclonal (Tau-5) |
| In order to elucidate the molecular mechanisms of ischemic tolerance, Invitrogen MAPT antibody (Biosource, AHB0042) was used in immunohistochemistry - paraffin section on rat samples at 1:1000 (fig 5) and in western blot on rat samples at 1:2000 (fig 4). Neurol Sci (2011) ncbi |
| mouse monoclonal (Tau-5) |
| In order to elucidate the between tau aggregation and the unfolded protein response in neurodegenerative disorders, Invitrogen MAPT antibody (Biosource, AHB0042) was used in western blot on human samples at 1:1000. J Neurosci Res (2010) ncbi |
| mouse monoclonal (Tau-5) |
| In order to test if HFE polymorphisms are associated with alterations in tau phosphorylation in a human neuroblastoma cell line, Invitrogen MAPT antibody (Biosource International, Tau-5) was used in ELISA on human samples (fig 1a). Neurobiol Aging (2011) ncbi |
| mouse monoclonal (Tau-5) |
| In order to assess the neuroprotective effects of delphinidin against Abeta-induced toxicity, Invitrogen MAPT antibody (Biosource, tau-5) was used in western blot on rat samples at 1:1000 (fig 3). Biosci Biotechnol Biochem (2009) ncbi |
| mouse monoclonal (Tau-5) |
| In order to investigate the potential neuroprotective effects of caffeic acid against Abeta-induced toxicity, Invitrogen MAPT antibody (Biosource, tau-5) was used in western blot on rat samples at 1:1000. Life Sci (2009) ncbi |
| mouse monoclonal (Tau-5) |
| In order to investigate the neurotoxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin, Invitrogen MAPT antibody (Biosource, tau-5) was used in western blot on mouse samples at 1:1000. Toxicology (2009) ncbi |
| mouse monoclonal (Tau-5) |
| In order to develop an electrophysiologically active 3D neural construct with neurons and astrocytes encased in a bioactive extracellular matrix-based scaffold, Invitrogen MAPT antibody (NeoMarkers, MS247P) was used in immunocytochemistry on rat samples at 1:200. J Neural Eng (2008) ncbi |
| mouse monoclonal (Tau-5) |
| In order to elucidate the neuroprotective mechanisms by which curcumin protects against Abeta-induced toxicity, Invitrogen MAPT antibody (Biosource, tau-5) was used in western blot on rat samples at 1:1000 (fig 6). Food Chem Toxicol (2008) ncbi |
| mouse monoclonal (Tau-5) |
| In order to evaluate if OVX/stress affects levels of Alzheimer's disease-related molecules in the mouse hippocampus, Invitrogen MAPT antibody (Invitrogen, TAU- 5) was used in western blot on mouse samples at 1:1000 (fig 3). Neurosci Lett (2008) ncbi |
| mouse monoclonal (Tau-5) |
| In order to determine that Abeta deposition or oestrogen deficiency increases PP2A phosphorylation to compromise tau dephosphorylation and cause neurofibrillary tangle formation in Alzheimer's disease, Invitrogen MAPT antibody (Biosource, Tau-5) was used in western blot on mouse samples at 1:1000 (fig 5). J Cell Mol Med (2008) ncbi |
| mouse monoclonal (Tau-5) |
| In order to evaluate five glycogen synthase kinase-3beta inhibitors and lithium in lowering phosphorylated tau and glycogen synthase kinase-3beta enzyme activity levels in 12-day old postnatal rats, Invitrogen MAPT antibody (BioSource/Invitrogen, tau-5) was used in western blot on rat samples at 1:5000. Br J Pharmacol (2007) ncbi |
| mouse monoclonal (Tau-5) |
| In order to isolate cis-acting regulatory elements for the generation of transgenic zebrafish models of neurodegeneration, Invitrogen MAPT antibody (Biosource, AHB0042) was used in immunohistochemistry - frozen section on human samples at 1:500 and in western blot on human samples at 1:500. Nucleic Acids Res (2007) ncbi |
| mouse monoclonal (Tau-5) |
| In order to identify and investigate Reelin-regulated signaling pathways in the brain, Invitrogen MAPT antibody (Biosource, AHB0042) was used in western blot on mouse samples (fig 4). Mol Cell Biol (2007) ncbi |
| mouse monoclonal (Tau-5) |
| In order to test if sex hormones prevent tau cleavage and Abeta toxicity, Invitrogen MAPT antibody (Biosource, tau-5) was used in western blot on rat samples at 1:1000 (fig 3). Neuroscience (2007) ncbi |
| mouse monoclonal (Tau-5) |
| In order to characterize a new mouse model of Alzheimer's disease, Invitrogen MAPT antibody (Biosource, Tau-5) was used in immunohistochemistry - paraffin section on human samples at 1:10,000 (tbl 1) and in western blot on human samples at 1:10,000 (tbl 1). Am J Pathol (2006) ncbi |
| mouse monoclonal (Tau-5) |
| In order to assess the effects lithium chloride on cold water stress-induced changes in tau phosphorylation in the mouse hippocampus, Invitrogen MAPT antibody (Biosource, TAU-5) was used in western blot on mouse samples . J Neural Transm (Vienna) (2006) ncbi |
| mouse monoclonal (Tau-5) |
| In order to elucidate how the removal of assembled neurofilaments from axons or misaccumulating neurofilaments in motor neuron cell bodies slows disease in a mouse model of amyotrophic lateral sclerosis, Invitrogen MAPT antibody (BioSource, Tau-5) was used in western blot on mouse samples at 1:1000. Proc Natl Acad Sci U S A (2005) ncbi |
| mouse monoclonal (Tau-5) |
| In order to test if calpain cleave the cyclin-dependent kinase 5 activator p35 to a p25 fragment and results in tau hyperphosphorylation, Invitrogen MAPT antibody (BioSource, tau-5) was used in western blot on rat samples . Biochem Biophys Res Commun (2002) ncbi |
Abcam
| mouse monoclonal (Tau-5) |
| Abcam MAPT antibody (Abcam, ab80579) was used in western blot on human samples (fig 1c, 1e, 1l, 2c) and in western blot on mouse samples (fig 5a). EBioMedicine (2022) ncbi |
| mouse monoclonal (Tau-5) |
| Abcam MAPT antibody (Abcam, ab80579) was used in immunocytochemistry on human samples (fig 2a) and in western blot on human samples at 1:2000 (fig 1a). Front Cell Dev Biol (2021) ncbi |
| mouse monoclonal (Tau-5) |
| Abcam MAPT antibody (Abcam, Ab80579) was used in western blot on mouse samples at 1:1000 (fig 8a). Ann Neurol (2021) ncbi |
| mouse monoclonal (Tau-5) |
| Abcam MAPT antibody (Abcam, ab80579) was used in western blot on rat samples at 1:1000 (fig 2a). Signal Transduct Target Ther (2021) ncbi |
| mouse monoclonal (Tau-5) |
| Abcam MAPT antibody (Abcam, ab80579) was used in western blot on mouse samples (fig 1a). Clin Transl Med (2021) ncbi |
| mouse monoclonal (Tau46) |
| Abcam MAPT antibody (Abcam, ab203179) was used in western blot on mouse samples at 1:500 (fig 2n). Int J Mol Sci (2021) ncbi |
| mouse monoclonal (Tau-5) |
| Abcam MAPT antibody (Abcam, ab80579) was used in western blot on mouse samples at 1:1000. Commun Biol (2021) ncbi |
| mouse monoclonal (Tau-5) |
| Abcam MAPT antibody (Abcam, ab80579) was used in western blot on mouse samples (fig 4a). Cell (2021) ncbi |
| mouse monoclonal (Tau-5) |
| Abcam MAPT antibody (Abcam, ab80579) was used in proximity ligation assay on mouse samples at 1:250 (fig s3) and in proximity ligation assay on human samples at 1:2000 (fig 1d). Acta Neuropathol Commun (2021) ncbi |
| mouse monoclonal (Tau-5) |
| Abcam MAPT antibody (Abcam, ab80579) was used in western blot on mouse samples (fig 1a, 1b). Neuropsychiatr Dis Treat (2020) ncbi |
| mouse monoclonal (Tau-5) |
| Abcam MAPT antibody (Abcam, ab80579) was used in western blot on mouse samples (fig 5e). J Neuroinflammation (2020) ncbi |
| mouse monoclonal (Tau-5) |
| Abcam MAPT antibody (Abcam, ab80579) was used in ELISA on human samples (fig 5a). Acta Neuropathol Commun (2019) ncbi |
| mouse monoclonal (Tau-5) |
| Abcam MAPT antibody (Abcam, ab80579) was used in western blot on human samples at 1:1000 (fig 1f). PLoS ONE (2019) ncbi |
| mouse monoclonal (Tau-5) |
| Abcam MAPT antibody (Abcam, ab80579) was used in western blot on human samples at 1:1000 (fig 1b, 2a). Aging Cell (2020) ncbi |
| mouse monoclonal (Tau-5) |
| Abcam MAPT antibody (AbCam, ab80579) was used in immunoprecipitation on human samples (fig 4b). elife (2019) ncbi |
| mouse monoclonal (Tau-5) |
| In order to validate antibodies against tau protein and its variants, Abcam MAPT antibody (Abcam, Tau5) was used in western blot on mouse samples , in western blot knockout validation on human samples at 1:1000 (tbl 1) and in immunocytochemistry on human samples at 1:50 (tbl 2). Mol Neurodegener (2017) ncbi |
| mouse monoclonal (Tau-5) |
| Abcam MAPT antibody (Abcam, ab80579) was used in immunocytochemistry on mouse samples at 1:250 (fig 2a). J Immunol Methods (2017) ncbi |
| mouse monoclonal (Tau-5) |
| Abcam MAPT antibody (Abcam, ab80579) was used in immunocytochemistry on rat samples (fig 1f). Mol Cell Neurosci (2017) ncbi |
| mouse monoclonal (Tau-5) |
| Abcam MAPT antibody (Abcam, ab80579) was used in immunocytochemistry on rat samples at 1:100 (fig 4d) and in western blot on rat samples at 1:500 (fig 4e). Sci Rep (2016) ncbi |
| mouse monoclonal (Tau-5) |
| Abcam MAPT antibody (Abcam, ab80579) was used in immunohistochemistry on human samples (fig 3). Aging Cell (2016) ncbi |
| mouse monoclonal (Tau-5) |
| In order to research differentiation of functional glutamatergic neurons from placenta-derived multipotent cells by knocking down of heat-shock protein 27, Abcam MAPT antibody (Abcam, ab80579) was used in immunocytochemistry on human samples at 1:100 (fig 4). Sci Rep (2016) ncbi |
| mouse monoclonal (Tau-5) |
| In order to ascertain the effects of severe penetrating traumatic brain injury on APP and tau cleavage processing, Abcam MAPT antibody (Abcam, ab80579) was used in western blot on rat samples at 1:1000 (fig 8). PLoS ONE (2016) ncbi |
| mouse monoclonal (Tau-5) |
| Abcam MAPT antibody (abcam, ab80579) was used in immunohistochemistry - paraffin section on mouse samples (fig 2c). PLoS ONE (2016) ncbi |
| mouse monoclonal (Tau-5) |
| In order to elucidate modification microglial phenotype and neuroprotection in P301S tau transgenic mice via TREM2, Abcam MAPT antibody (Abcam, ab80579) was used in western blot on human samples at 1:800 (fig 3) and in western blot on mouse samples at 1:800 (fig 3). Neuropharmacology (2016) ncbi |
| mouse monoclonal (Tau-5) |
| In order to use a pharmaceutical screen to discover new mechanisms of autophagy activation, Abcam MAPT antibody (Abcam, ab80579) was used in western blot on human samples at 1:5000 (fig 7). Nat Commun (2015) ncbi |
| mouse monoclonal (Tau-5) |
| Abcam MAPT antibody (Abcam, ab80579) was used in ELISA on human samples (fig 2a,b). Int J Mol Epidemiol Genet (2014) ncbi |
| mouse monoclonal (Tau-5) |
| In order to investigate the contribution of IL-12/23 to disease using SAMP8 mice, Abcam MAPT antibody (Abcam, ab80579) was used in western blot on mouse samples at 1:800 (fig 1). J Alzheimers Dis (2014) ncbi |
| mouse monoclonal (Tau-5) |
| Abcam MAPT antibody (Abcam, ab80579) was used in western blot on mouse samples at 1:2000. J Biol Chem (2013) ncbi |
| mouse monoclonal (Tau-5) |
| Abcam MAPT antibody (Abcam, Tau5) was used in immunoprecipitation on human samples and in western blot on human samples (fig 2a). Mol Psychiatry (2013) ncbi |
Santa Cruz Biotechnology
| mouse monoclonal (Tau-5) |
| In order to show that PTI-125 therapeutically alters filamin A and reverses proteopathy, Santa Cruz Biotechnology MAPT antibody (SantaCruz, SC-58860) was used in western blot on mouse samples (fig 5b). Neurobiol Aging (2017) ncbi |
| mouse monoclonal (Tau-5) |
| Santa Cruz Biotechnology MAPT antibody (Santa Cruz, sc-58860) was used in immunohistochemistry on mouse samples and in western blot on mouse samples . Mol Neurodegener (2015) ncbi |
| mouse monoclonal (Tau-5) |
| In order to determine if tau phosphorylation contributes to spinal muscular atrophy pathogenesis, Santa Cruz Biotechnology MAPT antibody (Santa Cruz Biotechnology, Tau-5) was used in immunohistochemistry on mouse samples at 1:100 and in western blot on mouse samples at 1:100. J Neurosci (2015) ncbi |
Cell Signaling Technology
| mouse monoclonal (Tau46) |
| Cell Signaling Technology MAPT antibody (Cell Signaling, 4019) was used in western blot on mouse samples (fig 1a). Nature (2019) ncbi |
| mouse monoclonal (Tau46) |
| Cell Signaling Technology MAPT antibody (Cell Signaling, 4019) was used in immunohistochemistry on mouse samples (fig 2a). J Clin Invest (2018) ncbi |
| mouse monoclonal (Tau46) |
| Cell Signaling Technology MAPT antibody (Cell Signaling, 4019) was used in western blot on rat samples (fig 3b). J Biol Chem (2018) ncbi |
| mouse monoclonal (Tau46) |
| Cell Signaling Technology MAPT antibody (Cell Signaling, 4019P) was used in western blot on rat samples at 1:1000 (fig 2). Neural Regen Res (2016) ncbi |
| mouse monoclonal (Tau46) |
| In order to analyze the mitigation that increases PHF1 levels and lipofuscin puncta and rescues memory deficits by TFEB overexpression in the P301S model of tauopathy, Cell Signaling Technology MAPT antibody (Cell Signaling Technology, 4019) was used in western blot on mouse samples (fig 6). Eneuro (2016) ncbi |
| mouse monoclonal (Tau46) |
| In order to study the effect of G2019S on neuronal subtypes, Cell Signaling Technology MAPT antibody (Cell Signal, 4019) was used in western blot on human samples . Stem Cell Reports (2015) ncbi |
| mouse monoclonal (Tau46) |
| In order to analyze a mouse model where human neural stem cells alleviate Alzheimer-like pathology, Cell Signaling Technology MAPT antibody (Cell Signaling Technology, 4019) was used in western blot on mouse samples at 1:1000 (fig 3). Mol Neurodegener (2015) ncbi |
| mouse monoclonal (Tau46) |
| In order to study an increase in tau phosphorylation via P38 mitogen-activated protein kinase dye to glucose deprivation, Cell Signaling Technology MAPT antibody (Cell signaling, 4019) was used in western blot on mouse samples (fig 1). Aging Cell (2015) ncbi |
| mouse monoclonal (Tau46) |
| Cell Signaling Technology MAPT antibody (Cell Signaling, 4019) was used in western blot on human samples at 1:1000 (fig 5). BMC Genomics (2015) ncbi |
| mouse monoclonal (Tau46) |
| Cell Signaling Technology MAPT antibody (Cell Signaling Technology, 4019S) was used in western blot on rat samples at 1:1000. Mol Neurobiol (2016) ncbi |
MilliporeSigma
| mouse monoclonal (Tau-2) |
| MilliporeSigma MAPT antibody (Sigma-Aldrich, T5530) was used in western blot on mouse samples at 1:1000. Front Aging Neurosci (2022) ncbi |
| mouse monoclonal (Tau46) |
| MilliporeSigma MAPT antibody (Sigma-Aldrich, T9450) was used in western blot on rat samples at 1:500 (fig 4a). Cell Rep (2022) ncbi |
| mouse monoclonal (Tau-2) |
| MilliporeSigma MAPT antibody (Sigma-Aldrich, T5530) was used in western blot on mouse samples at 1:1000 (fig s2d). J Neurochem (2022) ncbi |
| mouse monoclonal (Tau46) |
| MilliporeSigma MAPT antibody (Sigma, T9450) was used in western blot on rat samples at 1:1000 (fig 2f). Signal Transduct Target Ther (2021) ncbi |
| mouse monoclonal (Tau46) |
| MilliporeSigma MAPT antibody (Sigma, T9450) was used in immunocytochemistry on rat samples at 1:500 (fig 8e). Nat Commun (2019) ncbi |
| mouse monoclonal (Tau46) |
| In order to identify NFE2L2/NRF2 as a regulator of autophagy gene expression and study its role in Alzheimer disease, MilliporeSigma MAPT antibody (Sigma, T9450) was used in western blot on mouse samples at 1:4000 (fig 5b). Autophagy (2016) ncbi |
| mouse monoclonal (Tau46) |
| MilliporeSigma MAPT antibody (Sigma Aldrich, T9450) was used in western blot knockout validation on mouse samples at 1:500 (fig 1b). Neuroscience (2016) ncbi |
| mouse monoclonal (Tau-2) |
| In order to analyze a mouse model where human neural stem cells alleviate Alzheimer-like pathology, MilliporeSigma MAPT antibody (Sigma-Aldrich, T5530) was used in western blot on mouse samples at 1:1000 (fig 3). Mol Neurodegener (2015) ncbi |
| mouse monoclonal (Tau46) |
| In order to study how extracellular proteins are cleared from the brain, MilliporeSigma MAPT antibody (Sigma, T9450) was used in western blot on mouse samples . J Neurosci (2014) ncbi |
Articles Reviewed
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- Yoshitake J, Soeda Y, Ida T, Sumioka A, Yoshikawa M, Matsushita K, et al. Modification of Tau by 8-Nitroguanosine 3',5'-Cyclic Monophosphate (8-Nitro-cGMP): EFFECTS OF NITRIC OXIDE-LINKED CHEMICAL MODIFICATION ON TAU AGGREGATION. J Biol Chem. 2016;291:22714-22720 pubmed
- Pajares M, Jiménez Moreno N, García Yagüe A, Escoll M, De Ceballos M, Van Leuven F, et al. Transcription factor NFE2L2/NRF2 is a regulator of macroautophagy genes. Autophagy. 2016;12:1902-1916 pubmed
- Xu H, Rösler T, Carlsson T, de Andrade A, Fiala O, Höllerhage M, et al. Tau silencing by siRNA in the P301S mouse model of tauopathy. Curr Gene Ther. 2014;14:343-51 pubmed
- Melis V, Zabke C, Stamer K, Magbagbeolu M, Schwab K, Marschall P, et al. Different pathways of molecular pathophysiology underlie cognitive and motor tauopathy phenotypes in transgenic models for Alzheimer's disease and frontotemporal lobar degeneration. Cell Mol Life Sci. 2015;72:2199-222 pubmed publisher
- Richens J, Vere K, Light R, Soria D, Garibaldi J, Smith A, et al. Practical detection of a definitive biomarker panel for Alzheimer's disease; comparisons between matched plasma and cerebrospinal fluid. Int J Mol Epidemiol Genet. 2014;5:53-70 pubmed
- Maldonado H, RamÃrez E, Utreras E, Pando M, Kettlun A, Chiong M, et al. Inhibition of cyclin-dependent kinase 5 but not of glycogen synthase kinase 3-β prevents neurite retraction and tau hyperphosphorylation caused by secretable products of human T-cell leukemia virus type I-infected lymphocytes. J Neurosci Res. 2011;89:1489-98 pubmed publisher
- Kim H, Sul D, Lim J, Lee D, Joo S, Hwang K, et al. Delphinidin ameliorates beta-amyloid-induced neurotoxicity by inhibiting calcium influx and tau hyperphosphorylation. Biosci Biotechnol Biochem. 2009;73:1685-9 pubmed
- Selenica M, Jensen H, Larsen A, Pedersen M, Helboe L, Leist M, et al. Efficacy of small-molecule glycogen synthase kinase-3 inhibitors in the postnatal rat model of tau hyperphosphorylation. Br J Pharmacol. 2007;152:959-79 pubmed
- Bai Q, Garver J, Hukriede N, Burton E. Generation of a transgenic zebrafish model of Tauopathy using a novel promoter element derived from the zebrafish eno2 gene. Nucleic Acids Res. 2007;35:6501-16 pubmed
- Jossin Y, Goffinet A. Reelin signals through phosphatidylinositol 3-kinase and Akt to control cortical development and through mTor to regulate dendritic growth. Mol Cell Biol. 2007;27:7113-24 pubmed
- Park S, Tournell C, Sinjoanu R, Ferreira A. Caspase-3- and calpain-mediated tau cleavage are differentially prevented by estrogen and testosterone in beta-amyloid-treated hippocampal neurons. Neuroscience. 2007;144:119-27 pubmed
- Schindowski K, Bretteville A, Leroy K, Bégard S, Brion J, Hamdane M, et al. Alzheimer's disease-like tau neuropathology leads to memory deficits and loss of functional synapses in a novel mutated tau transgenic mouse without any motor deficits. Am J Pathol. 2006;169:599-616 pubmed
- Yoshida S, Maeda M, Kaku S, Ikeya H, Yamada K, Nakaike S. Lithium inhibits stress-induced changes in tau phosphorylation in the mouse hippocampus. J Neural Transm (Vienna). 2006;113:1803-14 pubmed
- Lobsiger C, Garcia M, Ward C, Cleveland D. Altered axonal architecture by removal of the heavily phosphorylated neurofilament tail domains strongly slows superoxide dismutase 1 mutant-mediated ALS. Proc Natl Acad Sci U S A. 2005;102:10351-6 pubmed
- Kerokoski P, Suuronen T, Salminen A, Soininen H, Pirttila T. Cleavage of the cyclin-dependent kinase 5 activator p35 to p25 does not induce tau hyperphosphorylation. Biochem Biophys Res Commun. 2002;298:693-8 pubmed
articles
- Tau antibody | knockout validation | Thermo Fisher Scientific MN1010
- Tau antibody | knockout validation | ThermoFisher Scientific MN1000
- Tau antibody | knockout validation | Sigma Aldrich T9450
- Tau5 antibody | knockout validation | Biosource AHB0042
- Tau antibody | knockout validation | ThermoFisher 13-6400
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