This is a Validated Antibody Database (VAD) review about bovine HDAC2, based on 12 published articles (read how Labome selects the articles), using HDAC2 antibody in all methods. It is aimed to help Labome visitors find the most suited HDAC2 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Abcam
mouse monoclonal (HDAC2-62)
  • western blot; mouse; 1:1000; loading ...; fig 1b, s3b
Abcam HDAC2 antibody (Abcam, ab12169) was used in western blot on mouse samples at 1:1000 (fig 1b, s3b). Epigenetics Chromatin (2022) ncbi
mouse monoclonal (HDAC2-62)
  • western blot; rat; 1:2000; loading ...; fig 5a
Abcam HDAC2 antibody (Abcam, ab12169) was used in western blot on rat samples at 1:2000 (fig 5a). Signal Transduct Target Ther (2021) ncbi
mouse monoclonal (HDAC2-62)
  • chromatin immunoprecipitation; mouse; loading ...; fig 4a
Abcam HDAC2 antibody (Abcam, ab12169) was used in chromatin immunoprecipitation on mouse samples (fig 4a). Nat Commun (2018) ncbi
mouse monoclonal (HDAC2-62)
  • chromatin immunoprecipitation; human; loading ...; fig s4b
  • western blot; human; 1:100; loading ...; fig 3a
Abcam HDAC2 antibody (Abcam, ab12169) was used in chromatin immunoprecipitation on human samples (fig s4b) and in western blot on human samples at 1:100 (fig 3a). Nat Commun (2018) ncbi
mouse monoclonal (HDAC2-62)
  • immunohistochemistry - frozen section; mouse; loading ...; fig 6b
In order to investigate the role of lysine specific demethylase 1 in neuronal maturation in the olfactory system, Abcam HDAC2 antibody (Abcam, ab12169) was used in immunohistochemistry - frozen section on mouse samples (fig 6b). J Comp Neurol (2017) ncbi
mouse monoclonal (3F3)
  • western blot; mouse; 1:2000; fig 4a
Abcam HDAC2 antibody (Abcam, ab51832) was used in western blot on mouse samples at 1:2000 (fig 4a). Front Cell Neurosci (2017) ncbi
mouse monoclonal (HDAC2-62)
  • ChIP-Seq; human; loading ...; fig s5o
  • western blot; human; loading ...; fig s5l
In order to demonstrate that iPS-derived cardiomyocytes with a heterozygous GATA4-G296S missense mutation show impaired contractility, calcium handling, and metabolic activity, Abcam HDAC2 antibody (Abcam, ab12169) was used in ChIP-Seq on human samples (fig s5o) and in western blot on human samples (fig s5l). Cell (2016) ncbi
mouse monoclonal (HDAC2-62)
  • western blot; mouse; 1:1000; loading ...; fig 6a
In order to examine the effect of piceatannol on renal fibrosis and histone deacetylase expression in a mouse model of unilateral ureteral obstruction, Abcam HDAC2 antibody (Abcam, ab12169) was used in western blot on mouse samples at 1:1000 (fig 6a). PLoS ONE (2016) ncbi
Santa Cruz Biotechnology
mouse monoclonal (3F3)
  • chromatin immunoprecipitation; human; loading ...; fig 4a
Santa Cruz Biotechnology HDAC2 antibody (Santa Cruz, sc-81599) was used in chromatin immunoprecipitation on human samples (fig 4a). Clin Epigenetics (2021) ncbi
mouse monoclonal (3F3)
  • western blot; human; fig 7c
Santa Cruz Biotechnology HDAC2 antibody (Santa Cruz Biotechnology, sc-81599) was used in western blot on human samples (fig 7c). iScience (2019) ncbi
mouse monoclonal (3F3)
  • western blot; mouse; 1:500
Santa Cruz Biotechnology HDAC2 antibody (Santa Cruz, sc-81599) was used in western blot on mouse samples at 1:500. Toxicol Appl Pharmacol (2015) ncbi
mouse monoclonal (3F3)
  • western blot; human; 1:1000; fig 2
Santa Cruz Biotechnology HDAC2 antibody (Santa Cruz, sc-81599) was used in western blot on human samples at 1:1000 (fig 2). Acta Neuropathol Commun (2015) ncbi
Articles Reviewed
  1. de Castro R, Carbajal A, Previato de Almeida L, Goitea V, Griffin C, Pezza R. Mouse Chd4-NURD is required for neonatal spermatogonia survival and normal gonad development. Epigenetics Chromatin. 2022;15:16 pubmed publisher
  2. Li J, Jin C, Sun L, Wang B, Hua P, Zhang Y. HDAC2 enhances esophageal squamous cell carcinoma development through down-regulating microRNA-503-5p and promoting CXCL10. Clin Epigenetics. 2021;13:96 pubmed publisher
  3. Xu S, Tao H, Cao W, Cao L, Lin Y, Zhao S, et al. Ketogenic diets inhibit mitochondrial biogenesis and induce cardiac fibrosis. Signal Transduct Target Ther. 2021;6:54 pubmed publisher
  4. Patel N, Wang J, Shiozawa K, Jones K, Zhang Y, Prokop J, et al. HDAC2 Regulates Site-Specific Acetylation of MDM2 and Its Ubiquitination Signaling in Tumor Suppression. iScience. 2019;13:43-54 pubmed publisher
  5. Singh A, Khare P, Obaid A, Conlon K, Basrur V, Depinho R, et al. SUMOylation of ROR-γt inhibits IL-17 expression and inflammation via HDAC2. Nat Commun. 2018;9:4515 pubmed publisher
  6. Lino Cardenas C, Kessinger C, Cheng Y, MacDonald C, Macgillivray T, Ghoshhajra B, et al. An HDAC9-MALAT1-BRG1 complex mediates smooth muscle dysfunction in thoracic aortic aneurysm. Nat Commun. 2018;9:1009 pubmed publisher
  7. Coleman J, Lin B, Schwob J. Dissecting LSD1-Dependent Neuronal Maturation in the Olfactory Epithelium. J Comp Neurol. 2017;525:3391-3413 pubmed publisher
  8. Jin X, Yu Z, Chen F, Lu G, Ding X, Xie L, et al. Neuronal Nitric Oxide Synthase in Neural Stem Cells Induces Neuronal Fate Commitment via the Inhibition of Histone Deacetylase 2. Front Cell Neurosci. 2017;11:66 pubmed publisher
  9. Ang Y, Rivas R, Ribeiro A, Srivas R, Rivera J, Stone N, et al. Disease Model of GATA4 Mutation Reveals Transcription Factor Cooperativity in Human Cardiogenesis. Cell. 2016;167:1734-1749.e22 pubmed publisher
  10. Choi S, Piao Z, Jin L, Kim J, Kim G, Ryu Y, et al. Piceatannol Attenuates Renal Fibrosis Induced by Unilateral Ureteral Obstruction via Downregulation of Histone Deacetylase 4/5 or p38-MAPK Signaling. PLoS ONE. 2016;11:e0167340 pubmed publisher
  11. Tyler C, Hafez A, Solomon E, Allan A. Developmental exposure to 50 parts-per-billion arsenic influences histone modifications and associated epigenetic machinery in a region- and sex-specific manner in the adult mouse brain. Toxicol Appl Pharmacol. 2015;288:40-51 pubmed publisher
  12. Ecker J, Oehme I, Mazitschek R, Korshunov A, Kool M, Hielscher T, et al. Targeting class I histone deacetylase 2 in MYC amplified group 3 medulloblastoma. Acta Neuropathol Commun. 2015;3:22 pubmed publisher