This is a Validated Antibody Database (VAD) review about bovine DNMT1, based on 25 published articles (read how Labome selects the articles), using DNMT1 antibody in all methods. It is aimed to help Labome visitors find the most suited DNMT1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
DNMT1 synonym: DNMT

Knockout validation
Cell Signaling Technology
domestic rabbit monoclonal (D63A6)
  • western blot knockout validation; human; 1:1000; loading ...; fig s7b
Cell Signaling Technology DNMT1 antibody (Cell Signaling, 5032) was used in western blot knockout validation on human samples at 1:1000 (fig s7b). J Immunother Cancer (2021) ncbi
Novus Biologicals
mouse monoclonal (60B1220.1)
  • western blot; mouse; fig 4a
Novus Biologicals DNMT1 antibody (Novus Biologicals, NB100-56519) was used in western blot on mouse samples (fig 4a). Sci Rep (2017) ncbi
mouse monoclonal (60B1220.1)
  • western blot; human; fig 6a
In order to assess the effects of the PCNA S228I mutation that causes proliferating cell nuclear antigen-associated DNA repair disorder, Novus Biologicals DNMT1 antibody (Novus Biologicals, NB100-56519) was used in western blot on human samples (fig 6a). DNA Repair (Amst) (2017) ncbi
mouse monoclonal (60B1220.1)
  • western blot; mouse; 1:1000
Novus Biologicals DNMT1 antibody (Novus Biologicals, 60B1220.1) was used in western blot on mouse samples at 1:1000. Biochim Biophys Acta (2015) ncbi
Invitrogen
mouse monoclonal (60B1220.1)
  • western blot; human; 1:1000; fig 4
In order to study the interaction between DNMT1 and HDAC2 and how they cooperate to facilitate aberrant promoter methylation in inorganic phosphate-induced endothelial-mesenchymal transition, Invitrogen DNMT1 antibody (Pierce, MA5-16169) was used in western blot on human samples at 1:1000 (fig 4). PLoS ONE (2016) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (D63A6)
  • western blot; human; 1:100; loading ...; fig 3d
Cell Signaling Technology DNMT1 antibody (Cell Signaling Technology, 5032) was used in western blot on human samples at 1:100 (fig 3d). J Clin Invest (2022) ncbi
domestic rabbit monoclonal (D63A6)
  • western blot; human; loading ...; fig 6b
Cell Signaling Technology DNMT1 antibody (Cell Signal, 5032) was used in western blot on human samples (fig 6b). Clin Transl Med (2021) ncbi
domestic rabbit monoclonal (D63A6)
  • western blot knockout validation; human; 1:1000; loading ...; fig s7b
Cell Signaling Technology DNMT1 antibody (Cell Signaling, 5032) was used in western blot knockout validation on human samples at 1:1000 (fig s7b). J Immunother Cancer (2021) ncbi
domestic rabbit monoclonal (D63A6)
  • western blot; human; 1:1000; loading ...
Cell Signaling Technology DNMT1 antibody (Cell Signaling, 5032) was used in western blot on human samples at 1:1000. Angiogenesis (2020) ncbi
domestic rabbit monoclonal (D63A6)
  • western blot; human; 1:5000; loading ...; fig 2f
Cell Signaling Technology DNMT1 antibody (CST, 5032) was used in western blot on human samples at 1:5000 (fig 2f). Sci Adv (2020) ncbi
domestic rabbit monoclonal (D63A6)
  • western blot; human; 1:1000; fig 1b
Cell Signaling Technology DNMT1 antibody (Cell Signaling Technology, 5032) was used in western blot on human samples at 1:1000 (fig 1b). JCI Insight (2020) ncbi
domestic rabbit monoclonal (D63A6)
  • western blot; mouse; loading ...; fig e5e
Cell Signaling Technology DNMT1 antibody (Cell Signaling Technology, 5032) was used in western blot on mouse samples (fig e5e). Nature (2020) ncbi
domestic rabbit monoclonal (D63A6)
  • western blot; human; loading ...; fig 4i
Cell Signaling Technology DNMT1 antibody (Cell Signaling, 5032) was used in western blot on human samples (fig 4i). Cancer Cell (2019) ncbi
domestic rabbit monoclonal (D59A4)
  • immunohistochemistry - frozen section; human; loading ...; fig s9b
  • western blot; human; fig 4g
In order to understand the role of nicotinamide metabolism in the maintenance of glioblastoma stem cells, Cell Signaling Technology DNMT1 antibody (Cell signaling, 5119) was used in immunohistochemistry - frozen section on human samples (fig s9b) and in western blot on human samples (fig 4g). JCI Insight (2017) ncbi
domestic rabbit monoclonal (D59A4)
  • immunohistochemistry - frozen section; human; loading ...; fig 3a
Cell Signaling Technology DNMT1 antibody (Cell signaling, D59A4) was used in immunohistochemistry - frozen section on human samples (fig 3a). Oncotarget (2017) ncbi
domestic rabbit monoclonal (D59A4)
  • western blot; mouse; loading ...; fig 4c
Cell Signaling Technology DNMT1 antibody (Cell Signaling, 5119S) was used in western blot on mouse samples (fig 4c). Cell Stem Cell (2017) ncbi
domestic rabbit monoclonal (D63A6)
  • western blot; human; fig 1
In order to investigate the contribution of DNA methyltransferase 1 to the epithelial-mesenchymal transition and cancer stem cells, Cell Signaling Technology DNMT1 antibody (Cell Signaling, 5032) was used in western blot on human samples (fig 1). Neoplasia (2016) ncbi
domestic rabbit monoclonal (D63A6)
  • immunohistochemistry; mouse; fig 6b
  • western blot; mouse; fig 5b
Cell Signaling Technology DNMT1 antibody (Cell Signaling Technology, 5032) was used in immunohistochemistry on mouse samples (fig 6b) and in western blot on mouse samples (fig 5b). J Clin Invest (2016) ncbi
domestic rabbit monoclonal (D63A6)
  • western blot; rat; 1:2500; fig 6
Cell Signaling Technology DNMT1 antibody (Cell Signaling Tech, 5032) was used in western blot on rat samples at 1:2500 (fig 6). PLoS ONE (2015) ncbi
domestic rabbit monoclonal (D63A6)
  • western blot; human
In order to study the relationship between nuclear LASP-1 and the epigenetic machinery in breast cancer, Cell Signaling Technology DNMT1 antibody (cst, 5032P) was used in western blot on human samples . Oncogene (2016) ncbi
domestic rabbit monoclonal (D63A6)
  • western blot; human; 1:1000; fig 3
Cell Signaling Technology DNMT1 antibody (Cell Signaling, 5032) was used in western blot on human samples at 1:1000 (fig 3). PLoS ONE (2015) ncbi
domestic rabbit monoclonal (D59A4)
  • western blot; rat; 1:1000; loading ...; fig 2d
Cell Signaling Technology DNMT1 antibody (Cell signaling, 5119) was used in western blot on rat samples at 1:1000 (fig 2d). Int J Neuropsychopharmacol (2014) ncbi
domestic rabbit monoclonal (D63A6)
  • western blot; mouse
Cell Signaling Technology DNMT1 antibody (Cell Signaling, 5032) was used in western blot on mouse samples . Science (2015) ncbi
domestic rabbit monoclonal (D59A4)
  • western blot; mouse; 1:1000; loading ...; fig 6a
Cell Signaling Technology DNMT1 antibody (Cell Signaling, 5119) was used in western blot on mouse samples at 1:1000 (fig 6a). Nat Commun (2014) ncbi
domestic rabbit monoclonal (D63A6)
  • western blot; human
Cell Signaling Technology DNMT1 antibody (Cell Signaling Technology, 5032) was used in western blot on human samples . Carcinogenesis (2014) ncbi
domestic rabbit monoclonal (D63A6)
  • western blot; human
Cell Signaling Technology DNMT1 antibody (Cell Signaling, 5032) was used in western blot on human samples . PLoS ONE (2013) ncbi
Articles Reviewed
  1. Dave J, Chakraborty R, Ntokou A, Saito J, Saddouk F, Feng Z, et al. JAGGED1/NOTCH3 activation promotes aortic hypermuscularization and stenosis in elastin deficiency. J Clin Invest. 2022;132: pubmed publisher
  2. Zhang Y, He L, Huang L, Yao S, Lin N, Li P, et al. Oncogenic PAX6 elicits CDK4/6 inhibitor resistance by epigenetically inactivating the LATS2-Hippo signaling pathway. Clin Transl Med. 2021;11:e503 pubmed publisher
  3. Wu S, Xiao Y, Wei J, Xu X, Jin X, Hu X, et al. MYC suppresses STING-dependent innate immunity by transcriptionally upregulating DNMT1 in triple-negative breast cancer. J Immunother Cancer. 2021;9: pubmed publisher
  4. Tacconi C, He Y, Ducoli L, Detmar M. Epigenetic regulation of the lineage specificity of primary human dermal lymphatic and blood vascular endothelial cells. Angiogenesis. 2020;: pubmed publisher
  5. Kim K, Wu Y, Yoon J, Adachi K, Wu G, Velychko S, et al. Reprogramming competence of OCT factors is determined by transactivation domains. Sci Adv. 2020;6: pubmed publisher
  6. de Cubas A, Dunker W, Zaninovich A, Hongo R, Bhatia A, Panda A, et al. DNA hypomethylation promotes transposable element expression and activation of immune signaling in renal cell cancer. JCI Insight. 2020;5: pubmed publisher
  7. Lu Z, Zou J, Li S, Topper M, Tao Y, Zhang H, et al. Epigenetic therapy inhibits metastases by disrupting premetastatic niches. Nature. 2020;579:284-290 pubmed publisher
  8. Sin Chan P, Mumal I, Suwal T, Ho B, Fan X, Singh I, et al. A C19MC-LIN28A-MYCN Oncogenic Circuit Driven by Hijacked Super-enhancers Is a Distinct Therapeutic Vulnerability in ETMRs: A Lethal Brain Tumor. Cancer Cell. 2019;36:51-67.e7 pubmed publisher
  9. Jung J, Kim L, Wang X, Wu Q, Sanvoranart T, Hubert C, et al. Nicotinamide metabolism regulates glioblastoma stem cell maintenance. JCI Insight. 2017;2: pubmed publisher
  10. Almeida L, Neto M, Sousa L, Tannous M, Curti C, Leopoldino A. SET oncoprotein accumulation regulates transcription through DNA demethylation and histone hypoacetylation. Oncotarget. 2017;8:26802-26818 pubmed publisher
  11. Choi J, Clement K, Huebner A, Webster J, Rose C, Brumbaugh J, et al. DUSP9 Modulates DNA Hypomethylation in Female Mouse Pluripotent Stem Cells. Cell Stem Cell. 2017;20:706-719.e7 pubmed publisher
  12. Raciti G, Spinelli R, Desiderio A, Longo M, Parrillo L, Nigro C, et al. Specific CpG hyper-methylation leads to Ankrd26 gene down-regulation in white adipose tissue of a mouse model of diet-induced obesity. Sci Rep. 2017;7:43526 pubmed publisher
  13. Wilson R, Biasutto A, Wang L, Fischer R, Baple E, Crosby A, et al. PCNA dependent cellular activities tolerate dramatic perturbations in PCNA client interactions. DNA Repair (Amst). 2017;50:22-35 pubmed publisher
  14. Lee E, Wang J, Yumoto K, Jung Y, Cackowski F, Decker A, et al. DNMT1 Regulates Epithelial-Mesenchymal Transition and Cancer Stem Cells, Which Promotes Prostate Cancer Metastasis. Neoplasia. 2016;18:553-66 pubmed publisher
  15. Tan X, Xu X, Zeisberg M, Zeisberg E. DNMT1 and HDAC2 Cooperate to Facilitate Aberrant Promoter Methylation in Inorganic Phosphate-Induced Endothelial-Mesenchymal Transition. PLoS ONE. 2016;11:e0147816 pubmed publisher
  16. Chang Y, Yang C, Pan S, Chou Y, Chang F, Lai C, et al. DNA methyltransferase inhibition restores erythropoietin production in fibrotic murine kidneys. J Clin Invest. 2016;126:721-31 pubmed publisher
  17. Götze S, Schumacher E, Kordes C, Häussinger D. Epigenetic Changes during Hepatic Stellate Cell Activation. PLoS ONE. 2015;10:e0128745 pubmed publisher
  18. Cicchini C, de Nonno V, Battistelli C, Cozzolino A, De Santis Puzzonia M, Ciafrè S, et al. Epigenetic control of EMT/MET dynamics: HNF4α impacts DNMT3s through miRs-29. Biochim Biophys Acta. 2015;1849:919-29 pubmed publisher
  19. Duvall Noelle N, Karwandyar A, Richmond A, Raman D. LASP-1: a nuclear hub for the UHRF1-DNMT1-G9a-Snail1 complex. Oncogene. 2016;35:1122-33 pubmed publisher
  20. Nakamura K, Nakabayashi K, Htet Aung K, Aizawa K, Hori N, Yamauchi J, et al. DNA methyltransferase inhibitor zebularine induces human cholangiocarcinoma cell death through alteration of DNA methylation status. PLoS ONE. 2015;10:e0120545 pubmed publisher
  21. Wei Y, Melas P, Wegener G, Mathé A, Lavebratt C. Antidepressant-like effect of sodium butyrate is associated with an increase in TET1 and in 5-hydroxymethylation levels in the Bdnf gene. Int J Neuropsychopharmacol. 2014;18: pubmed publisher
  22. Geula S, Moshitch Moshkovitz S, Dominissini D, Mansour A, Kol N, Salmon Divon M, et al. Stem cells. m6A mRNA methylation facilitates resolution of naïve pluripotency toward differentiation. Science. 2015;347:1002-6 pubmed publisher
  23. Feng X, Krogh K, Wu C, Lin Y, Tsai H, Thayer S, et al. Receptor-interacting protein 140 attenuates endoplasmic reticulum stress in neurons and protects against cell death. Nat Commun. 2014;5:4487 pubmed publisher
  24. Zhu Z, Liu Y, Li K, Liu J, Wang H, Sun B, et al. Protein tyrosine phosphatase receptor U (PTPRU) is required for glioma growth and motility. Carcinogenesis. 2014;35:1901-10 pubmed publisher
  25. Nakamura K, Aizawa K, Nakabayashi K, Kato N, Yamauchi J, Hata K, et al. DNA methyltransferase inhibitor zebularine inhibits human hepatic carcinoma cells proliferation and induces apoptosis. PLoS ONE. 2013;8:e54036 pubmed publisher