This is a Validated Antibody Database (VAD) review about Rhesus mon.. RORC, based on 39 published articles (read how Labome selects the articles), using RORC antibody in all methods. It is aimed to help Labome visitors find the most suited RORC antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
RORC synonym: nuclear receptor ROR-gamma

Invitrogen
rat monoclonal (AFKJS-9)
  • immunohistochemistry - frozen section; mouse; 1:30; loading ...; fig 1a
Invitrogen RORC antibody (eBioscience, AFKJS-9) was used in immunohistochemistry - frozen section on mouse samples at 1:30 (fig 1a). J Exp Med (2019) ncbi
rat monoclonal (AFKJS-9)
  • western blot; mouse; 1:1000; loading ...; fig s6
Invitrogen RORC antibody (eBioscience, 14-6988-82) was used in western blot on mouse samples at 1:1000 (fig s6). Nat Commun (2019) ncbi
rat monoclonal (AFKJS-9)
  • chromatin immunoprecipitation; mouse; loading ...; fig 1b
Invitrogen RORC antibody (eBioscience, AKFS9) was used in chromatin immunoprecipitation on mouse samples (fig 1b). Nat Commun (2018) ncbi
rat monoclonal (AFKJS-9)
  • flow cytometry; mouse; loading ...; fig s2b
Invitrogen RORC antibody (eBioscience, AFKJS-9) was used in flow cytometry on mouse samples (fig s2b). Eur J Immunol (2018) ncbi
rat monoclonal (AFKJS-9)
  • flow cytometry; human; loading ...; fig 1b
Invitrogen RORC antibody (eBioscience, AFKJS-501 9) was used in flow cytometry on human samples (fig 1b). Cancer Res (2018) ncbi
rat monoclonal (AFKJS-9)
  • flow cytometry; human; fig 1b
In order to study the involvement of Notch signaling in NK cell lineage determination, Invitrogen RORC antibody (ebioscience, AFKJS-9) was used in flow cytometry on human samples (fig 1b). J Immunol (2017) ncbi
rat monoclonal (AFKJS-9)
  • western blot; mouse; 1:200; loading ...; fig 2b
Invitrogen RORC antibody (eBioscience, AFKJS-9) was used in western blot on mouse samples at 1:200 (fig 2b). Nat Commun (2017) ncbi
rat monoclonal (AFKJS-9)
  • flow cytometry; mouse; loading ...; fig 5f
In order to investigate the role of the E-Id protein axis in the innate and adaptive lymphoid development, Invitrogen RORC antibody (Thermo Fisher Scientific, 12-6988-82) was used in flow cytometry on mouse samples (fig 5f). Immunity (2017) ncbi
rat monoclonal (AFKJS-9)
  • immunohistochemistry; human; 1:25; loading ...; fig 3a
In order to find that oral administration of a selective Rho-associated kinase 2 inhibitor, KD025, reduces psoriasis area in 46% of patients with psoriasis vulgaris, Invitrogen RORC antibody (eBioscience, 14-6988) was used in immunohistochemistry on human samples at 1:25 (fig 3a). J Immunol (2017) ncbi
rat monoclonal (AFKJS-9)
  • flow cytometry; human; fig s3c
  • flow cytometry; mouse; loading ...; fig 4c
In order to study the differentiation of innate lymphoid cells, Invitrogen RORC antibody (eBioscience, 17-6988) was used in flow cytometry on human samples (fig s3c) and in flow cytometry on mouse samples (fig 4c). Cell (2017) ncbi
rat monoclonal (AFKJS-9)
  • flow cytometry; mouse; 1:400; loading ...; fig 4a
In order to report a CD40-dependent mechanism capable of abrogating inducible T regulatory cell induction by dendritic cells, Invitrogen RORC antibody (eBioscience, AFKJS-9) was used in flow cytometry on mouse samples at 1:400 (fig 4a). Nat Commun (2017) ncbi
rat monoclonal (AFKJS-9)
  • flow cytometry; mouse; loading ...; fig 7k
In order to identify protein arginine methyltransferase 5 as an important modulator of CD4(+) T cell expansion, Invitrogen RORC antibody (eBioscience, 12-698880) was used in flow cytometry on mouse samples (fig 7k). J Immunol (2017) ncbi
rat monoclonal (AFKJS-9)
  • flow cytometry; mouse; loading ...; fig 3
In order to examine natural killer T cell development in mice deficient for SLAM family receptors, Invitrogen RORC antibody (eBioscience, AFKJS-9) was used in flow cytometry on mouse samples (fig 3). J Exp Med (2017) ncbi
rat monoclonal (AFKJS-9)
  • flow cytometry; mouse; loading ...; fig 6b
In order to elucidate how P2X7 regulates the contraction of intestinal CD4 positive effector T cells, Invitrogen RORC antibody (eBioscience, AFKJS-9) was used in flow cytometry on mouse samples (fig 6b). Mucosal Immunol (2017) ncbi
rat monoclonal (AFKJS-9)
  • flow cytometry; mouse; loading ...; fig 3g
In order to determine the effect of a high salt diet on intestinal immunity and the risk of inflammatory bowel disease, Invitrogen RORC antibody (eBioscience, AFKJS-9) was used in flow cytometry on mouse samples (fig 3g). Oncotarget (2017) ncbi
rat monoclonal (AFKJS-9)
  • flow cytometry; mouse; loading ...; fig s3g
Invitrogen RORC antibody (eBioscience, AFKJS-9) was used in flow cytometry on mouse samples (fig s3g). Immunity (2016) ncbi
rat monoclonal (AFKJS-9)
  • flow cytometry; mouse; loading ...; fig 1b
In order to explain how glial cells impact ILC3-derived IL-22, Invitrogen RORC antibody (eBioscience, AFKJS-9) was used in flow cytometry on mouse samples (fig 1b). Nature (2016) ncbi
rat monoclonal (AFKJS-9)
  • flow cytometry; mouse; fig 5
Invitrogen RORC antibody (eBioscience, AFKJ-9) was used in flow cytometry on mouse samples (fig 5). Sci Rep (2016) ncbi
rat monoclonal (AFKJS-9)
  • immunohistochemistry; mouse; 1:100; fig 2
Invitrogen RORC antibody (eBioscience, AFKJS-9) was used in immunohistochemistry on mouse samples at 1:100 (fig 2). Nat Commun (2016) ncbi
rat monoclonal (AFKJS-9)
  • flow cytometry; Rhesus monkey; fig 3b
Invitrogen RORC antibody (eBiosciences, AFKJS-9) was used in flow cytometry on Rhesus monkey samples (fig 3b). J Immunol (2016) ncbi
rat monoclonal (AFKJS-9)
  • immunocytochemistry; human; fig 4e
  • western blot; human; fig 4b
In order to study JAK/STAT, Aspergillus fumigatus corneal infections and IL-6/23-stimulated neutrophil, IL-17, elastase, and MMP9 activity, Invitrogen RORC antibody (eBiosciences, AFKJS-9) was used in immunocytochemistry on human samples (fig 4e) and in western blot on human samples (fig 4b). J Leukoc Biol (2016) ncbi
rat monoclonal (AFKJS-9)
  • flow cytometry; mouse; fig 1
Invitrogen RORC antibody (e-Bioscience, 12-6988) was used in flow cytometry on mouse samples (fig 1). Nat Commun (2016) ncbi
rat monoclonal (AFKJS-9)
  • flow cytometry; mouse; loading ...; fig 4
In order to test whether heat-killed Staphyloccocus aureus inhibits the development of atherosclerosis, Invitrogen RORC antibody (eBioscience, AFKJS-9) was used in flow cytometry on mouse samples (fig 4). J Intern Med (2016) ncbi
rat monoclonal (AFKJS-9)
  • flow cytometry; mouse; fig 7
Invitrogen RORC antibody (eBioscience, 17-6988-82) was used in flow cytometry on mouse samples (fig 7). Eur J Immunol (2016) ncbi
rat monoclonal (AFKJS-9)
  • immunohistochemistry - frozen section; mouse; loading ...; fig 2e
In order to explore the contributions of GATA3 to the group 3 innate lymphoid cells, Invitrogen RORC antibody (eBioscience, AFKJS-9) was used in immunohistochemistry - frozen section on mouse samples (fig 2e). Nat Immunol (2016) ncbi
rat monoclonal (AFKJS-9)
  • flow cytometry; mouse; loading ...; fig s6
In order to report a role for effector T helper type 2 cells during T cell receptor-independent innate-like immune responses, Invitrogen RORC antibody (eBiosciences, AFKJs-9) was used in flow cytometry on mouse samples (fig s6). Nat Immunol (2015) ncbi
rat monoclonal (AFKJS-9)
  • flow cytometry; mouse; loading ...; fig s2c
In order to discuss tissue tropisms of innate lymphoid cells, Invitrogen RORC antibody (Thermo Fisher Scientific, AFKJS-9) was used in flow cytometry on mouse samples (fig s2c). Immunity (2015) ncbi
rat monoclonal (AFKJS-9)
  • flow cytometry; mouse; fig 5
In order to assess IL-25 and IL-23 and reciprocal regulation of lymphoid tissue development in the large intestine, Invitrogen RORC antibody (Ebioscience, AFKJS-9) was used in flow cytometry on mouse samples (fig 5). Mucosal Immunol (2015) ncbi
rat monoclonal (AFKJS-9)
  • flow cytometry; mouse; 1:200
Invitrogen RORC antibody (eBiosciences, AFKJS-9) was used in flow cytometry on mouse samples at 1:200. Cancer Res (2014) ncbi
rat monoclonal (AFKJS-9)
  • western blot; human; fig 5b
Invitrogen RORC antibody (eBioscience, 14-6988) was used in western blot on human samples (fig 5b). J Biol Chem (2014) ncbi
rat monoclonal (AFKJS-9)
  • immunohistochemistry - frozen section; mouse
  • flow cytometry; human
Invitrogen RORC antibody (eBioscience, AFKJS-9) was used in immunohistochemistry - frozen section on mouse samples and in flow cytometry on human samples . J Exp Med (2014) ncbi
rat monoclonal (AFKJS-9)
  • flow cytometry; mouse
Invitrogen RORC antibody (eBioscience, clone AFKJS-9) was used in flow cytometry on mouse samples . PLoS ONE (2014) ncbi
rat monoclonal (AFKJS-9)
  • flow cytometry; mouse
In order to demonstrate that CTLA-4 promotes Tc17 differentiation and robust Tc17 responses, Invitrogen RORC antibody (eBioscience, AFKJS-9) was used in flow cytometry on mouse samples . Eur J Immunol (2014) ncbi
rat monoclonal (AFKJS-9)
  • flow cytometry; mouse
Invitrogen RORC antibody (ebioscience, 17-6988-80) was used in flow cytometry on mouse samples . Exp Parasitol (2014) ncbi
rat monoclonal (AFKJS-9)
  • flow cytometry; human; tbl 1
In order to study the effect of innate lymphoid cells on B cells, Invitrogen RORC antibody (eBioscience, AFKJS-9) was used in flow cytometry on human samples (tbl 1). Nat Immunol (2014) ncbi
rat monoclonal (AFKJS-9)
  • flow cytometry; mouse
  • immunocytochemistry; mouse
Invitrogen RORC antibody (eBioscience, AFKJS-9) was used in flow cytometry on mouse samples and in immunocytochemistry on mouse samples . Eur J Immunol (2014) ncbi
rat monoclonal (AFKJS-9)
  • flow cytometry; mouse
In order to identify CD11b(+) classical dendritic cells as the source of IL-23 in C. rodentium infected mice, Invitrogen RORC antibody (eBioscience, AFKJS-9) was used in flow cytometry on mouse samples . Nat Immunol (2013) ncbi
rat monoclonal (AFKJS-9)
  • flow cytometry; human
In order to use semantic connectivity maps to find biomarkers for multiple sclerosis, Invitrogen RORC antibody (eBioscience, AFKJS-9) was used in flow cytometry on human samples . Immun Ageing (2013) ncbi
rat monoclonal (AFKJS-9)
  • flow cytometry; mouse
In order to examine IL-7R signaling in Tbx21 and Rag2 knockout mice, Invitrogen RORC antibody (eBioscience, AFKJS-9) was used in flow cytometry on mouse samples . Immunity (2012) ncbi
Articles Reviewed
  1. Melo Gonzalez F, Kammoun H, Evren E, Dutton E, Papadopoulou M, Bradford B, et al. Antigen-presenting ILC3 regulate T cell-dependent IgA responses to colonic mucosal bacteria. J Exp Med. 2019;216:728-742 pubmed publisher
  2. Cho J, Xu Z, Parthasarathy U, Drashansky T, Helm E, Zuniga A, et al. Hectd3 promotes pathogenic Th17 lineage through Stat3 activation and Malt1 signaling in neuroinflammation. Nat Commun. 2019;10:701 pubmed publisher
  3. Singh A, Khare P, Obaid A, Conlon K, Basrur V, Depinho R, et al. SUMOylation of ROR-γt inhibits IL-17 expression and inflammation via HDAC2. Nat Commun. 2018;9:4515 pubmed publisher
  4. Jones R, Cosway E, Willis C, White A, Jenkinson W, Fehling H, et al. Dynamic changes in intrathymic ILC populations during murine neonatal development. Eur J Immunol. 2018;48:1481-1491 pubmed publisher
  5. Hu X, Majchrzak K, Liu X, Wyatt M, Spooner C, Moisan J, et al. In Vitro Priming of Adoptively Transferred T Cells with a RORγ Agonist Confers Durable Memory and Stemness In Vivo. Cancer Res. 2018;78:3888-3898 pubmed publisher
  6. Kyoizumi S, Kubo Y, Kajimura J, Yoshida K, Hayashi T, Nakachi K, et al. Fate Decision Between Group 3 Innate Lymphoid and Conventional NK Cell Lineages by Notch Signaling in Human Circulating Hematopoietic Progenitors. J Immunol. 2017;199:2777-2793 pubmed publisher
  7. Hasan Z, Koizumi S, Sasaki D, Yamada H, Arakaki N, Fujihara Y, et al. JunB is essential for IL-23-dependent pathogenicity of Th17 cells. Nat Commun. 2017;8:15628 pubmed publisher
  8. Miyazaki M, Miyazaki K, Chen K, Jin Y, Turner J, Moore A, et al. The E-Id Protein Axis Specifies Adaptive Lymphoid Cell Identity and Suppresses Thymic Innate Lymphoid Cell Development. Immunity. 2017;46:818-834.e4 pubmed publisher
  9. Zanin Zhorov A, Weiss J, Trzeciak A, Chen W, Zhang J, Nyuydzefe M, et al. Cutting Edge: Selective Oral ROCK2 Inhibitor Reduces Clinical Scores in Patients with Psoriasis Vulgaris and Normalizes Skin Pathology via Concurrent Regulation of IL-17 and IL-10. J Immunol. 2017;198:3809-3814 pubmed publisher
  10. Lim A, Li Y, Lopez Lastra S, Stadhouders R, Paul F, Casrouge A, et al. Systemic Human ILC Precursors Provide a Substrate for Tissue ILC Differentiation. Cell. 2017;168:1086-1100.e10 pubmed publisher
  11. Barthels C, Ogrinc A, Steyer V, Meier S, Simon F, Wimmer M, et al. CD40-signalling abrogates induction of RORγt+ Treg cells by intestinal CD103+ DCs and causes fatal colitis. Nat Commun. 2017;8:14715 pubmed publisher
  12. Webb L, Amici S, Jablonski K, Savardekar H, Panfil A, Li L, et al. PRMT5-Selective Inhibitors Suppress Inflammatory T Cell Responses and Experimental Autoimmune Encephalomyelitis. J Immunol. 2017;198:1439-1451 pubmed publisher
  13. Chen S, Cai C, Li Z, Liu G, Wang Y, Blonska M, et al. Dissection of SAP-dependent and SAP-independent SLAM family signaling in NKT cell development and humoral immunity. J Exp Med. 2017;214:475-489 pubmed publisher
  14. Hashimoto Hill S, Friesen L, Kim M, Kim C. Contraction of intestinal effector T cells by retinoic acid-induced purinergic receptor P2X7. Mucosal Immunol. 2017;10:912-923 pubmed publisher
  15. Wei Y, Lu C, Chen J, Cui G, Wang L, Yu T, et al. High salt diet stimulates gut Th17 response and exacerbates TNBS-induced colitis in mice. Oncotarget. 2017;8:70-82 pubmed publisher
  16. Wang S, Xia P, Chen Y, Huang G, Xiong Z, Liu J, et al. Natural Killer-like B Cells Prime Innate Lymphocytes against Microbial Infection. Immunity. 2016;45:131-44 pubmed publisher
  17. Ibiza S, García Cassani B, Ribeiro H, Carvalho T, Almeida L, Marques R, et al. Glial-cell-derived neuroregulators control type 3 innate lymphoid cells and gut defence. Nature. 2016;535:440-443 pubmed publisher
  18. Brandstätter O, Schanz O, Vorac J, König J, Mori T, Maruyama T, et al. Balancing intestinal and systemic inflammation through cell type-specific expression of the aryl hydrocarbon receptor repressor. Sci Rep. 2016;6:26091 pubmed publisher
  19. Li Z, Hodgkinson T, Gothard E, Boroumand S, Lamb R, Cummins I, et al. Epidermal Notch1 recruits RORγ(+) group 3 innate lymphoid cells to orchestrate normal skin repair. Nat Commun. 2016;7:11394 pubmed publisher
  20. Rueda C, Presicce P, Jackson C, Miller L, Kallapur S, Jobe A, et al. Lipopolysaccharide-Induced Chorioamnionitis Promotes IL-1-Dependent Inflammatory FOXP3+ CD4+ T Cells in the Fetal Rhesus Macaque. J Immunol. 2016;196:3706-15 pubmed publisher
  21. Taylor P, Roy S, Meszaros E, Sun Y, Howell S, Malemud C, et al. JAK/STAT regulation of Aspergillus fumigatus corneal infections and IL-6/23-stimulated neutrophil, IL-17, elastase, and MMP9 activity. J Leukoc Biol. 2016;100:213-22 pubmed publisher
  22. Tosiek M, Fiette L, El Daker S, Eberl G, Freitas A. IL-15-dependent balance between Foxp3 and RORγt expression impacts inflammatory bowel disease. Nat Commun. 2016;7:10888 pubmed publisher
  23. Frodermann V, Van Duijn J, van Puijvelde G, van Santbrink P, Lagraauw H, de Vries M, et al. Heat-killed Staphylococcus aureus reduces atherosclerosis by inducing anti-inflammatory macrophages. J Intern Med. 2016;279:592-605 pubmed publisher
  24. Carrascal J, Carrillo J, Arpa B, Egia Mendikute L, Rosell Mases E, Pujol Autonell I, et al. B-cell anergy induces a Th17 shift in a novel B lymphocyte transgenic NOD mouse model, the 116C-NOD mouse. Eur J Immunol. 2016;46:593-608 pubmed publisher
  25. Zhong C, Cui K, Wilhelm C, Hu G, Mao K, Belkaid Y, et al. Group 3 innate lymphoid cells continuously require the transcription factor GATA-3 after commitment. Nat Immunol. 2016;17:169-78 pubmed publisher
  26. Guo L, Huang Y, Chen X, Hu Li J, Urban J, Paul W. Innate immunological function of TH2 cells in vivo. Nat Immunol. 2015;16:1051-9 pubmed publisher
  27. Kim M, Taparowsky E, Kim C. Retinoic Acid Differentially Regulates the Migration of Innate Lymphoid Cell Subsets to the Gut. Immunity. 2015;43:107-19 pubmed publisher
  28. Donaldson D, Bradford B, Artis D, Mabbott N. Reciprocal regulation of lymphoid tissue development in the large intestine by IL-25 and IL-23. Mucosal Immunol. 2015;8:582-95 pubmed publisher
  29. Chatterjee S, Thyagarajan K, Kesarwani P, Song J, Soloshchenko M, Fu J, et al. Reducing CD73 expression by IL1?-Programmed Th17 cells improves immunotherapeutic control of tumors. Cancer Res. 2014;74:6048-59 pubmed publisher
  30. Han L, Yang J, Wang X, Wu Q, Yin S, Li Z, et al. The E3 deubiquitinase USP17 is a positive regulator of retinoic acid-related orphan nuclear receptor ?t (ROR?t) in Th17 cells. J Biol Chem. 2014;289:25546-55 pubmed publisher
  31. Longman R, Diehl G, Victorio D, Huh J, Galan C, Miraldi E, et al. CX?CR1? mononuclear phagocytes support colitis-associated innate lymphoid cell production of IL-22. J Exp Med. 2014;211:1571-83 pubmed publisher
  32. Weitkamp J, Rosen M, Zhao Z, Koyama T, Geem D, Denning T, et al. Small intestinal intraepithelial TCR??+ T lymphocytes are present in the premature intestine but selectively reduced in surgical necrotizing enterocolitis. PLoS ONE. 2014;9:e99042 pubmed publisher
  33. Pick J, Arra A, Lingel H, Hegel J, Huber M, Nishanth G, et al. CTLA-4 (CD152) enhances the Tc17 differentiation program. Eur J Immunol. 2014;44:2139-52 pubmed publisher
  34. Keswani T, Bhattacharyya A. Differential role of T regulatory and Th17 in Swiss mice infected with Plasmodium berghei ANKA and Plasmodium yoelii. Exp Parasitol. 2014;141:82-92 pubmed publisher
  35. Magri G, Miyajima M, Bascones S, Mortha A, Puga I, Cassis L, et al. Innate lymphoid cells integrate stromal and immunological signals to enhance antibody production by splenic marginal zone B cells. Nat Immunol. 2014;15:354-364 pubmed publisher
  36. McGuire D, Rowse A, Li H, Peng B, Sestero C, Cashman K, et al. CD5 enhances Th17-cell differentiation by regulating IFN-? response and ROR?t localization. Eur J Immunol. 2014;44:1137-42 pubmed publisher
  37. Satpathy A, Briseño C, Lee J, Ng D, Manieri N, Kc W, et al. Notch2-dependent classical dendritic cells orchestrate intestinal immunity to attaching-and-effacing bacterial pathogens. Nat Immunol. 2013;14:937-48 pubmed publisher
  38. Gironi M, Saresella M, Rovaris M, Vaghi M, Nemni R, Clerici M, et al. A novel data mining system points out hidden relationships between immunological markers in multiple sclerosis. Immun Ageing. 2013;10:1 pubmed publisher
  39. Powell N, Walker A, Stolarczyk E, Canavan J, Gökmen M, Marks E, et al. The transcription factor T-bet regulates intestinal inflammation mediated by interleukin-7 receptor+ innate lymphoid cells. Immunity. 2012;37:674-84 pubmed publisher