This is a Validated Antibody Database (VAD) review about Rhesus mon.. MS4A1, based on 53 published articles (read how Labome selects the articles), using MS4A1 antibody in all methods. It is aimed to help Labome visitors find the most suited MS4A1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
MS4A1 synonym: B-lymphocyte antigen CD20; Membrane-spanning 4-domains subfamily A member 1

others
  • immunohistochemistry; mouse; 1:40; loading ...; fig 7c
 MS4A1 antibody (Invitrogen, L26) was used in immunohistochemistry on mouse samples at 1:40 (fig 7c). Oncogene (2018) ncbi
BioLegend
mouse monoclonal (2H7)
  • flow cytometry; human; loading ...; fig 1c, 4a
BioLegend MS4A1 antibody (BioLegend, 302304) was used in flow cytometry on human samples (fig 1c, 4a). J Exp Med (2018) ncbi
mouse monoclonal (2H7)
  • flow cytometry; human; loading ...; fig s6d
BioLegend MS4A1 antibody (Biolegend, 2H7) was used in flow cytometry on human samples (fig s6d). Cell (2018) ncbi
mouse monoclonal (2H7)
  • flow cytometry; human; loading ...; fig 6b
BioLegend MS4A1 antibody (BioLegend, 2H7) was used in flow cytometry on human samples (fig 6b). Front Immunol (2018) ncbi
mouse monoclonal (2H7)
  • flow cytometry; human; loading ...; fig 1a
BioLegend MS4A1 antibody (Biolegend, 302302) was used in flow cytometry on human samples (fig 1a). Cell (2018) ncbi
mouse monoclonal (2H7)
  • flow cytometry; human; loading ...; fig s1
BioLegend MS4A1 antibody (BioLegend, 302303) was used in flow cytometry on human samples (fig s1). Eur J Immunol (2018) ncbi
mouse monoclonal (2H7)
  • flow cytometry; African green monkey; loading ...; fig s10a
BioLegend MS4A1 antibody (BioLegend, 302336) was used in flow cytometry on African green monkey samples (fig s10a). J Clin Invest (2018) ncbi
mouse monoclonal (2H7)
  • flow cytometry; human; loading ...; fig s2a
BioLegend MS4A1 antibody (BioLegend, 2H7) was used in flow cytometry on human samples (fig s2a). J Virol (2018) ncbi
mouse monoclonal (2H7)
  • flow cytometry; human; loading ...; fig 1b
BioLegend MS4A1 antibody (Biolegend, 2H7) was used in flow cytometry on human samples (fig 1b). J Immunol (2018) ncbi
mouse monoclonal (2H7)
  • flow cytometry; human; fig 1a
In order to study the involvement of Notch signaling in NK cell lineage determination, BioLegend MS4A1 antibody (biolegend, 2H7) was used in flow cytometry on human samples (fig 1a). J Immunol (2017) ncbi
mouse monoclonal (2H7)
  • flow cytometry; human; loading ...; tbl 1
In order to assess the use of dried formats of the lymphocytosis screening tube and of the primary immune deficiency orientation tube, BioLegend MS4A1 antibody (BioLegend, 302328) was used in flow cytometry on human samples (tbl 1). J Immunol Methods (2017) ncbi
mouse monoclonal (2H7)
  • flow cytometry; human; loading ...; fig s1c
In order to discuss how mutations in PIK3CD and PIK3R1 cause activated PI3K-delta syndrome, BioLegend MS4A1 antibody (Biolegend, 2H7) was used in flow cytometry on human samples (fig s1c). Clin Immunol (2017) ncbi
mouse monoclonal (2H7)
  • flow cytometry; Rhesus monkey; loading ...
In order to examine the kinetics of SIV-specific CD8+ T cell cytolytic factor expression in peripheral blood, lymph node, spleen, and gut mucosa from early acute infection through chronic infection, BioLegend MS4A1 antibody (Biolegend, 2H7) was used in flow cytometry on Rhesus monkey samples . PLoS Pathog (2016) ncbi
mouse monoclonal (2H7)
  • flow cytometry; Rhesus monkey; loading ...; fig 7a
In order to study the efficacy of nanoparticle adjuvants for inducing protective immunity against simian immunodeficiency virus, BioLegend MS4A1 antibody (Biolegend, 2H7) was used in flow cytometry on Rhesus monkey samples (fig 7a). J Virol (2017) ncbi
mouse monoclonal (2H7)
  • flow cytometry; human; fig s4a
In order to study the contribution of T follicular helper cells to islet autoimmunity, BioLegend MS4A1 antibody (Biolegend, 2H7) was used in flow cytometry on human samples (fig s4a). Proc Natl Acad Sci U S A (2016) ncbi
mouse monoclonal (2H7)
  • flow cytometry; human; loading ...; fig 1a
In order to investigate how differences in B cell populations may contribute to HIV susceptibility, BioLegend MS4A1 antibody (Biolegend, 2H7) was used in flow cytometry on human samples (fig 1a). AIDS Res Hum Retroviruses (2016) ncbi
mouse monoclonal (2H7)
  • flow cytometry; human; loading ...
BioLegend MS4A1 antibody (Biolegend, 2H7) was used in flow cytometry on human samples . J Allergy Clin Immunol (2016) ncbi
mouse monoclonal (2H7)
  • flow cytometry; human; loading ...; fig 1a
In order to characterize B cells and antibody repertoires from injection drug users, BioLegend MS4A1 antibody (Biolegend, 2H7) was used in flow cytometry on human samples (fig 1a). PLoS ONE (2016) ncbi
mouse monoclonal (2H7)
  • flow cytometry; human; fig 6a
BioLegend MS4A1 antibody (BioLegend, 2H7) was used in flow cytometry on human samples (fig 6a). J Biol Chem (2016) ncbi
mouse monoclonal (2H7)
  • flow cytometry; Rhesus monkey; loading ...
In order to optimize vaccination with Aventis Pasteur's canarypox vector-HIV, BioLegend MS4A1 antibody (BioLegend, 302334) was used in flow cytometry on Rhesus monkey samples . Nat Med (2016) ncbi
mouse monoclonal (2H7)
  • flow cytometry; human; loading ...; tbl 1
BioLegend MS4A1 antibody (BioLegend, 2H7) was used in flow cytometry on human samples (tbl 1). J Immunol (2016) ncbi
mouse monoclonal (2H7)
  • flow cytometry; human; loading ...; tbl s1
In order to explore how junctional adhesion molecule family members differentially regulate CXCR4 function and CXCL12 secretion in the bone marrow niche, BioLegend MS4A1 antibody (Biolegend, 302308) was used in flow cytometry on human samples (tbl s1). Stem Cells (2016) ncbi
mouse monoclonal (2H7)
  • immunohistochemistry - frozen section; human; 1:50; fig 6
In order to determine how induced arthritis can be effectively treated by CTRP6, BioLegend MS4A1 antibody (Biolegend, 302301) was used in immunohistochemistry - frozen section on human samples at 1:50 (fig 6). Nat Commun (2015) ncbi
mouse monoclonal (2H7)
  • flow cytometry; human; loading ...; tbl 1
In order to compare the use of CD229, CD54, and CD319 expression for the identification of normal and aberrant plasma cells, BioLegend MS4A1 antibody (BioLegend, 2H7) was used in flow cytometry on human samples (tbl 1). Cytometry B Clin Cytom (2016) ncbi
mouse monoclonal (2H7)
  • flow cytometry; human; loading ...; fig 5a
BioLegend MS4A1 antibody (BioLegend, 2H7) was used in flow cytometry on human samples (fig 5a). Ann Rheum Dis (2016) ncbi
mouse monoclonal (2H7)
  • flow cytometry; human; fig 5
BioLegend MS4A1 antibody (Biolegend, # 302304) was used in flow cytometry on human samples (fig 5). Biomaterials (2015) ncbi
mouse monoclonal (2H7)
  • flow cytometry; human
BioLegend MS4A1 antibody (Biolegend, 2H7) was used in flow cytometry on human samples . PLoS ONE (2015) ncbi
mouse monoclonal (2H7)
  • flow cytometry; human
  • flow cytometry; crab-eating macaque
BioLegend MS4A1 antibody (Biolegend, 302314) was used in flow cytometry on human samples and in flow cytometry on crab-eating macaque samples . MAbs (2015) ncbi
mouse monoclonal (2H7)
  • flow cytometry; human; fig 1
BioLegend MS4A1 antibody (Biolegend, 2H7) was used in flow cytometry on human samples (fig 1). Int Immunol (2015) ncbi
mouse monoclonal (2H7)
  • flow cytometry; African green monkey
BioLegend MS4A1 antibody (Biolegend, 2H7) was used in flow cytometry on African green monkey samples . Am J Transplant (2015) ncbi
mouse monoclonal (2H7)
  • flow cytometry; Rhesus monkey
BioLegend MS4A1 antibody (BioLegend, 2H7) was used in flow cytometry on Rhesus monkey samples . J Infect Dis (2015) ncbi
mouse monoclonal (2H7)
  • flow cytometry; Rhesus monkey
BioLegend MS4A1 antibody (Biolegend, 2H7) was used in flow cytometry on Rhesus monkey samples . Antimicrob Agents Chemother (2014) ncbi
mouse monoclonal (2H7)
  • flow cytometry; human
BioLegend MS4A1 antibody (BioLegend, 2H7) was used in flow cytometry on human samples . PLoS ONE (2014) ncbi
Invitrogen
mouse monoclonal (L26)
  • immunohistochemistry - paraffin section; human; loading ...; fig 7g
Invitrogen MS4A1 antibody (eBioscience, L26) was used in immunohistochemistry - paraffin section on human samples (fig 7g). J Clin Invest (2018) ncbi
mouse monoclonal (L26)
  • immunohistochemistry - frozen section; human; loading ...; fig 2a
Invitrogen MS4A1 antibody (eBioscience, L26) was used in immunohistochemistry - frozen section on human samples (fig 2a). J Exp Med (2018) ncbi
mouse monoclonal (L26)
  • immunocytochemistry; African green monkey; loading ...; fig 1c
Invitrogen MS4A1 antibody (eBiosciences, 42-0202-82) was used in immunocytochemistry on African green monkey samples (fig 1c). J Clin Invest (2018) ncbi
mouse monoclonal (L26)
  • immunohistochemistry; mouse; 1:40; loading ...; fig 7c
Invitrogen MS4A1 antibody (Invitrogen, L26) was used in immunohistochemistry on mouse samples at 1:40 (fig 7c). Oncogene (2018) ncbi
mouse monoclonal (L26)
  • immunohistochemistry; human; 1:250; loading ...
In order to present the case of a patient with gingival and both palatine tonsils localization of a grade-two angiosarcoma, Invitrogen MS4A1 antibody (THERMO SCIENTIFIC, L26) was used in immunohistochemistry on human samples at 1:250. Rare Tumors (2016) ncbi
mouse monoclonal (L26)
  • immunohistochemistry - paraffin section; human; 1:300; loading ...
In order to define features that distinguish follicular lymphoma without a BCL2 translocation from nodal marginal zone lymphoma, Invitrogen MS4A1 antibody (Thermo Scientific, L26) was used in immunohistochemistry - paraffin section on human samples at 1:300. J Hematop (2016) ncbi
mouse monoclonal (L26)
  • immunohistochemistry - frozen section; human; 1:25; loading ...; tbl 1
In order to examine immune cells and chemokines present in human second-trimester fetal skin, Invitrogen MS4A1 antibody (EBioscience, L26) was used in immunohistochemistry - frozen section on human samples at 1:25 (tbl 1). Wound Repair Regen (2016) ncbi
mouse monoclonal (L26)
  • immunohistochemistry - paraffin section; human; 1:100; fig 3
In order to compare multiple sclerosis to autoimmune encephalitis in humans, Invitrogen MS4A1 antibody (Neomarkers, MS-340-S) was used in immunohistochemistry - paraffin section on human samples at 1:100 (fig 3). Acta Neuropathol Commun (2015) ncbi
mouse monoclonal (L26)
  • immunohistochemistry - paraffin section; human; 1:250; fig 3
In order to present the case of a patient with a history of patch-stage mycosis fungoides who later developed widespread lichen sclerosus-like lesions histopathologically consistent with interstitial mycosis fungoides, Invitrogen MS4A1 antibody (Thermo Scientific, L26) was used in immunohistochemistry - paraffin section on human samples at 1:250 (fig 3). Am J Dermatopathol (2016) ncbi
mouse monoclonal (L26)
  • immunohistochemistry - paraffin section; marmosets; loading ...; fig 5b
In order to test a therapeutic antibody against CD127 in a mouse model of experimental autoimmune encephalomyelitis, Invitrogen MS4A1 antibody (Thermo Scientific, L26) was used in immunohistochemistry - paraffin section on marmosets samples (fig 5b). J Neuroimmune Pharmacol (2016) ncbi
mouse monoclonal (L26)
  • immunohistochemistry; human
Invitrogen MS4A1 antibody (Thermo Scientific, L26) was used in immunohistochemistry on human samples . Histochem Cell Biol (2015) ncbi
mouse monoclonal (L26)
  • immunohistochemistry; human; 1:250
In order to discuss diagnostic challenges involved with folliculotropic mycosis fungoides, Invitrogen MS4A1 antibody (Thermo Scientific, L26) was used in immunohistochemistry on human samples at 1:250. J Cutan Pathol (2015) ncbi
mouse monoclonal (L26)
  • immunohistochemistry - paraffin section; human; 1:50
Invitrogen MS4A1 antibody (Zymed, L26) was used in immunohistochemistry - paraffin section on human samples at 1:50. J Eur Acad Dermatol Venereol (2015) ncbi
mouse monoclonal (L26)
  • immunohistochemistry - paraffin section; human
Invitrogen MS4A1 antibody (Thermo Scientific, L26) was used in immunohistochemistry - paraffin section on human samples . Cancer Immunol Immunother (2015) ncbi
mouse monoclonal (L26)
  • immunohistochemistry - paraffin section; human
Invitrogen MS4A1 antibody (Thermo Scientific, clone L26) was used in immunohistochemistry - paraffin section on human samples . PLoS ONE (2014) ncbi
mouse monoclonal (L26)
  • immunohistochemistry - paraffin section; human; 1:100
In order to report on a case of CD30-positive extranodal natural killer/T-cell lymphoma, Invitrogen MS4A1 antibody (Zymed, L26) was used in immunohistochemistry - paraffin section on human samples at 1:100. Oncol Lett (2014) ncbi
mouse monoclonal (L26)
  • immunohistochemistry - paraffin section; human; 1:100; fig 1
In order to investigate the mechanisms that lead to demyelination and neurodegeneration, Invitrogen MS4A1 antibody (Neomarkers, MS-340-S) was used in immunohistochemistry - paraffin section on human samples at 1:100 (fig 1). Brain (2013) ncbi
mouse monoclonal (L26)
  • flow cytometry; human; 1:100; tbl 3
In order to characterize extranodal natural killer/T-cell lymphoma, nasal type using patient samples, Invitrogen MS4A1 antibody (ZYMED, L26) was used in flow cytometry on human samples at 1:100 (tbl 3). Cytopathology (2012) ncbi
mouse monoclonal (L26)
  • immunohistochemistry - paraffin section; human; fig 2
In order to study AID-related changes in chronic rhinosinusitis with nasal polyps, Invitrogen MS4A1 antibody (Thermo Scientific, L26) was used in immunohistochemistry - paraffin section on human samples (fig 2). PLoS ONE (2011) ncbi
Bio-Rad
mouse monoclonal (2H7)
  • flow cytometry; human; loading ...; fig s2b
In order to suggest that persistent immune activation causes impairment of lymphocytes to respond to chemotactic stimuli, preventing their trafficking from the blood stream to peripheral organs, Bio-Rad MS4A1 antibody (AbD Serotec, 2H7) was used in flow cytometry on human samples (fig s2b). J Immunol (2017) ncbi
mouse monoclonal (2H7)
  • flow cytometry; human; fig 1
Bio-Rad MS4A1 antibody (ABD Serotec, MCA1710PB) was used in flow cytometry on human samples (fig 1). Cytometry B Clin Cytom (2014) ncbi
mouse monoclonal (2H7)
  • flow cytometry; human; 1:5
Bio-Rad MS4A1 antibody (Serotec, MCA1710A488T) was used in flow cytometry on human samples at 1:5. Anal Chem (2013) ncbi
Articles Reviewed
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  2. Bradley T, Peppa D, Pedroza Pacheco I, Li D, Cain D, Henao R, et al. RAB11FIP5 Expression and Altered Natural Killer Cell Function Are Associated with Induction of HIV Broadly Neutralizing Antibody Responses. Cell. 2018;175:387-399.e17 pubmed publisher
  3. Dam E, Maier A, Hocking A, Carlin J, Buckner J. Increased Binding of Specificity Protein 1 to the IL21R Promoter in B Cells Results in Enhanced B Cell Responses in Rheumatoid Arthritis. Front Immunol. 2018;9:1978 pubmed publisher
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  6. Kityo C, Makamdop K, Rothenberger M, Chipman J, Hoskuldsson T, Beilman G, et al. Lymphoid tissue fibrosis is associated with impaired vaccine responses. J Clin Invest. 2018;128:2763-2773 pubmed publisher
  7. Sayin I, Radtke A, Vella L, Jin W, Wherry E, Buggert M, et al. Spatial distribution and function of T follicular regulatory cells in human lymph nodes. J Exp Med. 2018;215:1531-1542 pubmed publisher
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  9. Wang L, Shi W, Chappell J, Joyce M, Zhang Y, Kanekiyo M, et al. Importance of Neutralizing Monoclonal Antibodies Targeting Multiple Antigenic Sites on the Middle East Respiratory Syndrome Coronavirus Spike Glycoprotein To Avoid Neutralization Escape. J Virol. 2018;92: pubmed publisher
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  12. Kyoizumi S, Kubo Y, Kajimura J, Yoshida K, Hayashi T, Nakachi K, et al. Fate Decision Between Group 3 Innate Lymphoid and Conventional NK Cell Lineages by Notch Signaling in Human Circulating Hematopoietic Progenitors. J Immunol. 2017;199:2777-2793 pubmed publisher
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  23. Wittmann A, Lamprinaki D, Bowles K, Katzenellenbogen E, Knirel Y, Whitfield C, et al. Dectin-2 Recognizes Mannosylated O-antigens of Human Opportunistic Pathogens and Augments Lipopolysaccharide Activation of Myeloid Cells. J Biol Chem. 2016;291:17629-38 pubmed publisher
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  27. Walraven M, Talhout W, Beelen R, van Egmond M, Ulrich M. Healthy human second-trimester fetal skin is deficient in leukocytes and associated homing chemokines. Wound Repair Regen. 2016;24:533-41 pubmed publisher
  28. Chang C, Hale S, Cox C, Blair A, Kronsteiner B, Grabowska R, et al. Junctional Adhesion Molecule-A Is Highly Expressed on Human Hematopoietic Repopulating Cells and Associates with the Key Hematopoietic Chemokine Receptor CXCR4. Stem Cells. 2016;34:1664-78 pubmed publisher
  29. Höftberger R, Leisser M, Bauer J, Lassmann H. Autoimmune encephalitis in humans: how closely does it reflect multiple sclerosis ?. Acta Neuropathol Commun. 2015;3:80 pubmed publisher
  30. Tekin B, Kempf W, Seckin D, Ergun T, Yucelten D, Demirkesen C. Interstitial Mycosis Fungoides With Lichen Sclerosus-Like Clinical and Histopathological Features. Am J Dermatopathol. 2016;38:138-43 pubmed publisher
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  32. Dunham J, Lee L, van Driel N, Laman J, Ni I, Zhai W, et al. Blockade of CD127 Exerts a Dichotomous Clinical Effect in Marmoset Experimental Autoimmune Encephalomyelitis. J Neuroimmune Pharmacol. 2016;11:73-83 pubmed publisher
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  35. Holzapfel B, Hutmacher D, Nowlan B, Barbier V, Thibaudeau L, Theodoropoulos C, et al. Tissue engineered humanized bone supports human hematopoiesis in vivo. Biomaterials. 2015;61:103-14 pubmed publisher
  36. de Winde C, Zuidscherwoude M, Vasaturo A, van der Schaaf A, Figdor C, van Spriel A. Multispectral imaging reveals the tissue distribution of tetraspanins in human lymphoid organs. Histochem Cell Biol. 2015;144:133-46 pubmed publisher
  37. Strick Marchand H, Dusséaux M, Darche S, Huntington N, Legrand N, Masse Ranson G, et al. A novel mouse model for stable engraftment of a human immune system and human hepatocytes. PLoS ONE. 2015;10:e0119820 pubmed publisher
  38. Nambiar J, Clarke A, Shim D, Mabon D, Tian C, Windloch K, et al. Potent neutralizing anti-CD1d antibody reduces lung cytokine release in primate asthma model. MAbs. 2015;7:638-50 pubmed publisher
  39. Inui M, Hirota S, Hirano K, Fujii H, Sugahara Tobinai A, Ishii T, et al. Human CD43+ B cells are closely related not only to memory B cells phenotypically but also to plasmablasts developmentally in healthy individuals. Int Immunol. 2015;27:345-55 pubmed publisher
  40. Kwun J, Page E, Hong J, GIBBY A, Yoon J, Farris A, et al. Neutralizing BAFF/APRIL with atacicept prevents early DSA formation and AMR development in T cell depletion induced nonhuman primate AMR model. Am J Transplant. 2015;15:815-22 pubmed publisher
  41. Li H, Evans T, Gillis J, Connole M, Reeves R. Bone marrow-imprinted gut-homing of plasmacytoid dendritic cells (pDCs) in acute simian immunodeficiency virus infection results in massive accumulation of hyperfunctional CD4+ pDCs in the mucosae. J Infect Dis. 2015;211:1717-25 pubmed publisher
  42. Demirkesen C, Esirgen G, Engin B, Songur A, OÄŸuz O. The clinical features and histopathologic patterns of folliculotropic mycosis fungoides in a series of 38 cases. J Cutan Pathol. 2015;42:22-31 pubmed publisher
  43. Jabbour M, Issa G, Charafeddine K, Simaan Y, Karam M, Khalifeh H, et al. The immune microenvironment in cutaneous leishmaniasis. J Eur Acad Dermatol Venereol. 2015;29:1170-9 pubmed publisher
  44. Novinger L, Ashikaga T, Krag D. Identification of tumor-binding scFv derived from clonally related B cells in tumor and lymph node of a patient with breast cancer. Cancer Immunol Immunother. 2015;64:29-39 pubmed publisher
  45. Del Prete G, Shoemaker R, Oswald K, Lara A, Trubey C, Fast R, et al. Effect of suberoylanilide hydroxamic acid (SAHA) administration on the residual virus pool in a model of combination antiretroviral therapy-mediated suppression in SIVmac239-infected indian rhesus macaques. Antimicrob Agents Chemother. 2014;58:6790-806 pubmed publisher
  46. Kusner L, Ciesielski M, Marx A, Kaminski H, Fenstermaker R. Survivin as a potential mediator to support autoreactive cell survival in myasthenia gravis: a human and animal model study. PLoS ONE. 2014;9:e102231 pubmed publisher
  47. Meshcheryakova A, Tamandl D, Bajna E, Stift J, Mittlboeck M, Svoboda M, et al. B cells and ectopic follicular structures: novel players in anti-tumor programming with prognostic power for patients with metastatic colorectal cancer. PLoS ONE. 2014;9:e99008 pubmed publisher
  48. Yang Y, Li Y, Liu Y, Yang M, Liu K. CD30+ extranodal natural killer/T-cell lymphoma mimicking phlegmonous myositis: A case report. Oncol Lett. 2014;7:1419-1421 pubmed
  49. Fischer M, Wimmer I, Hoftberger R, Gerlach S, Haider L, Zrzavy T, et al. Disease-specific molecular events in cortical multiple sclerosis lesions. Brain. 2013;136:1799-815 pubmed publisher
  50. Greig B, Stetler Stevenson M, Lea J. Stabilization media increases recovery in paucicellular cerebrospinal fluid specimens submitted for flow cytometry testing. Cytometry B Clin Cytom. 2014;86:135-8 pubmed publisher
  51. Young E, Berthier E, Beebe D. Assessment of enhanced autofluorescence and impact on cell microscopy for microfabricated thermoplastic devices. Anal Chem. 2013;85:44-9 pubmed publisher
  52. Su X, Huang J, Jiang Y, Tang Y, Li G, Liu W. Serous effusion cytology of extranodal natural killer/T-cell lymphoma. Cytopathology. 2012;23:96-102 pubmed publisher
  53. Mechtcheriakova D, Sobanov Y, Holtappels G, Bajna E, Svoboda M, Jaritz M, et al. Activation-induced cytidine deaminase (AID)-associated multigene signature to assess impact of AID in etiology of diseases with inflammatory component. PLoS ONE. 2011;6:e25611 pubmed publisher