This is a Validated Antibody Database (VAD) review about Rhesus mon.. ICOS, based on 48 published articles (read how Labome selects the articles), using ICOS antibody in all methods. It is aimed to help Labome visitors find the most suited ICOS antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
ICOS synonym: inducible T-cell costimulator

BioLegend
hamsters monoclonal (C398.4A)
  • flow cytometry; mouse; loading ...; fig 5a
BioLegend ICOS antibody (Biolegend, C398.4A) was used in flow cytometry on mouse samples (fig 5a). Front Immunol (2019) ncbi
hamsters monoclonal (C398.4A)
  • flow cytometry; mouse; loading ...; fig s16b
BioLegend ICOS antibody (Biolegend, C398.4A) was used in flow cytometry on mouse samples (fig s16b). Science (2019) ncbi
hamsters monoclonal (C398.4A)
  • mass cytometry; human; loading ...; fig 2b
BioLegend ICOS antibody (Biolegend, 313502) was used in mass cytometry on human samples (fig 2b). Cell (2019) ncbi
hamsters monoclonal (C398.4A)
  • flow cytometry; mouse; loading ...; fig s5l
BioLegend ICOS antibody (Biolegend, 313510) was used in flow cytometry on mouse samples (fig s5l). Cell (2019) ncbi
hamsters monoclonal (C398.4A)
  • flow cytometry; mouse; loading ...; fig 1c
BioLegend ICOS antibody (BioLegend, 313529) was used in flow cytometry on mouse samples (fig 1c). Cell (2019) ncbi
hamsters monoclonal (C398.4A)
  • flow cytometry; mouse; fig s3c
  • flow cytometry; rat; fig s3c
  • flow cytometry; human; loading ...; fig s3c
BioLegend ICOS antibody (BioLegend, 313540) was used in flow cytometry on mouse samples (fig s3c), in flow cytometry on rat samples (fig s3c) and in flow cytometry on human samples (fig s3c). Immunity (2018) ncbi
hamsters monoclonal (C398.4A)
  • flow cytometry; mouse; 1:400; loading ...; fig 4d
BioLegend ICOS antibody (Biolegend, C398.4A) was used in flow cytometry on mouse samples at 1:400 (fig 4d). Nat Commun (2018) ncbi
hamsters monoclonal (C398.4A)
  • flow cytometry; human; loading ...; fig s1a
BioLegend ICOS antibody (BioLegend, C398.4A) was used in flow cytometry on human samples (fig s1a). J Clin Invest (2018) ncbi
hamsters monoclonal (C398.4A)
  • flow cytometry; mouse; 1:200; loading ...; fig 2c
BioLegend ICOS antibody (Biolegend, C398.4A) was used in flow cytometry on mouse samples at 1:200 (fig 2c). Nat Commun (2017) ncbi
hamsters monoclonal (C398.4A)
  • flow cytometry; mouse; loading ...; fig s1h
In order to investigate the role of IL-4Ralpha-mediated macrophage activation promote in lung and liver wound repair, BioLegend ICOS antibody (BioLegend, C398.4A) was used in flow cytometry on mouse samples (fig s1h). Science (2017) ncbi
hamsters monoclonal (C398.4A)
  • mass cytometry; human; fig s8
BioLegend ICOS antibody (BioLegend, 313502) was used in mass cytometry on human samples (fig s8). Nature (2017) ncbi
hamsters monoclonal (C398.4A)
  • flow cytometry; human; loading ...; fig s2a
BioLegend ICOS antibody (BioLegend, C.398.4A) was used in flow cytometry on human samples (fig s2a). JCI Insight (2017) ncbi
hamsters monoclonal (C398.4A)
  • flow cytometry; human
  • flow cytometry; mouse; loading ...; fig 2b
In order to assess whether human T-cell leukemia virus type 1 bZIP factor enhances the proliferation of expressing T cells after stimulation via the T-cell receptor, BioLegend ICOS antibody (BioLegend, C398.4A) was used in flow cytometry on human samples and in flow cytometry on mouse samples (fig 2b). PLoS Pathog (2017) ncbi
hamsters monoclonal (C398.4A)
  • flow cytometry; human; loading ...; fig 2a
In order to study the contribution of T follicular helper cells to islet autoimmunity, BioLegend ICOS antibody (Biolegend, C398.4A) was used in flow cytometry on human samples (fig 2a). Proc Natl Acad Sci U S A (2016) ncbi
hamsters monoclonal (C398.4A)
  • flow cytometry; mouse; loading ...
In order to study the effect of IL-13 and IL-33 pathways in dysregulated type 2 inflammation., BioLegend ICOS antibody (Biolegend, C398.4A) was used in flow cytometry on mouse samples . J Allergy Clin Immunol (2017) ncbi
hamsters monoclonal (C398.4A)
  • flow cytometry; mouse; loading ...; fig st1
In order to determine the contribution of IL-33 and ST2 to eosinophil homeostasis, BioLegend ICOS antibody (BioLegend, C398.4A) was used in flow cytometry on mouse samples (fig st1). J Immunol (2016) ncbi
hamsters monoclonal (C398.4A)
  • flow cytometry; mouse; loading ...; fig 6d
In order to investigate allergic responses to food allergens in WASP-deficient animals, BioLegend ICOS antibody (Biolegend, C398.4A) was used in flow cytometry on mouse samples (fig 6d). J Clin Invest (2016) ncbi
hamsters monoclonal (C398.4A)
  • flow cytometry; mouse; 1:200; loading ...; tbl s2
In order to identify and characterize follicular cytotoxic T cells, BioLegend ICOS antibody (Biolegend, C398.4A) was used in flow cytometry on mouse samples at 1:200 (tbl s2). Nat Immunol (2016) ncbi
hamsters monoclonal (C398.4A)
  • flow cytometry; Rhesus monkey; loading ...
In order to optimize vaccination with Aventis Pasteur's canarypox vector-HIV, BioLegend ICOS antibody (BioLegend, 313520) was used in flow cytometry on Rhesus monkey samples . Nat Med (2016) ncbi
hamsters monoclonal (C398.4A)
  • flow cytometry; human; loading ...; fig 1b
BioLegend ICOS antibody (BioLegend, C398.4A) was used in flow cytometry on human samples (fig 1b). Nat Immunol (2016) ncbi
hamsters monoclonal (C398.4A)
  • flow cytometry; human; loading ...; fig 3
In order to study the pharmacologic inhibition of PI3K and MEK pathways in mixed cultures of human mononuclear cells., BioLegend ICOS antibody (BioLegend, C398.4A) was used in flow cytometry on human samples (fig 3). Am J Transplant (2016) ncbi
hamsters monoclonal (C398.4A)
  • flow cytometry; mouse; loading ...; fig 4c
In order to propose that neuronal autoimmunity is a pathogenic feature of type 1 diabetes, BioLegend ICOS antibody (Biolegend, C398.4A) was used in flow cytometry on mouse samples (fig 4c). Diabetes (2016) ncbi
hamsters monoclonal (C398.4A)
  • flow cytometry; human
In order to evaluate the promotion of B cell activation and CXCR4 downregulation by CD161 and LLT1 expression in human germinal centers, BioLegend ICOS antibody (BioLegend, C398.4A) was used in flow cytometry on human samples . J Immunol (2016) ncbi
hamsters monoclonal (C398.4A)
  • flow cytometry; African green monkey; fig 1
In order to study lymph node-resident simian immunodeficiency virus env-specific T follicular helper cells due to vaccine induction in Rhesus Macaques, BioLegend ICOS antibody (Biolegend, C398.4A) was used in flow cytometry on African green monkey samples (fig 1). J Immunol (2016) ncbi
hamsters monoclonal (C398.4A)
  • flow cytometry; mouse; fig s4
BioLegend ICOS antibody (biolegend, C398.4A) was used in flow cytometry on mouse samples (fig s4). Theranostics (2015) ncbi
hamsters monoclonal (C398.4A)
BioLegend ICOS antibody (BioLegend, 313510) was used . Nat Commun (2015) ncbi
hamsters monoclonal (C398.4A)
  • flow cytometry; mouse
BioLegend ICOS antibody (BioLegend, 313516) was used in flow cytometry on mouse samples . J Leukoc Biol (2015) ncbi
hamsters monoclonal (C398.4A)
  • blocking or activating experiments; mouse; 20 ug/ml; fig 7
BioLegend ICOS antibody (Biolegend, C398.4A) was used in blocking or activating experiments on mouse samples at 20 ug/ml (fig 7). J Immunol (2015) ncbi
hamsters monoclonal (C398.4A)
  • flow cytometry; rat; fig 3
BioLegend ICOS antibody (BioLegend, C398.4A) was used in flow cytometry on rat samples (fig 3). Eur J Immunol (2015) ncbi
hamsters monoclonal (C398.4A)
BioLegend ICOS antibody (BioLegend, C398.4a) was used . J Immunol (2014) ncbi
hamsters monoclonal (C398.4A)
  • flow cytometry; Rhesus monkey; loading ...; fig s1c
In order to explore germinal center-related hyperimmune responses and disease severity during viral infection, BioLegend ICOS antibody (Biolegend, C398.4A) was used in flow cytometry on Rhesus monkey samples (fig s1c). J Immunol (2014) ncbi
hamsters monoclonal (C398.4A)
  • flow cytometry; human; 1:100
BioLegend ICOS antibody (Biolegend, c398.4A) was used in flow cytometry on human samples at 1:100. J Clin Invest (2014) ncbi
Invitrogen
hamsters monoclonal (C398.4A)
  • flow cytometry; mouse; loading ...; fig s6b
Invitrogen ICOS antibody (eBiosciences, C398.4A) was used in flow cytometry on mouse samples (fig s6b). Nat Commun (2018) ncbi
hamsters monoclonal (C398.4A)
  • flow cytometry; mouse; 1:500; loading ...; fig s12c
Invitrogen ICOS antibody (Thermo Fisher Scientific, 17-9949-82) was used in flow cytometry on mouse samples at 1:500 (fig s12c). Nat Commun (2018) ncbi
hamsters monoclonal (C398.4A)
  • flow cytometry; mouse; loading ...; fig 2a
Invitrogen ICOS antibody (eBiosciences, C398.4A) was used in flow cytometry on mouse samples (fig 2a). Cancer Cell (2018) ncbi
hamsters monoclonal (C398.4A)
  • flow cytometry; mouse; loading ...; fig 4d
Invitrogen ICOS antibody (eBioscience, C398.4A) was used in flow cytometry on mouse samples (fig 4d). J Immunol (2018) ncbi
hamsters monoclonal (C398.4A)
  • flow cytometry; mouse; loading ...; fig 2a
Invitrogen ICOS antibody (eBioscience, C398.4A) was used in flow cytometry on mouse samples (fig 2a). J Exp Med (2018) ncbi
hamsters monoclonal (C398.4A)
  • flow cytometry; mouse; loading ...; fig 4d
In order to investigate the involvement of achaete-scute complex homologue 2 in the pathogenesis of Sjogren's syndrome-like disease in the NOD/ShiLtJ mouse, Invitrogen ICOS antibody (eBioscience, C398.4A) was used in flow cytometry on mouse samples (fig 4d). Immunol Lett (2017) ncbi
hamsters monoclonal (C398.4A)
  • flow cytometry; mouse; fig 4a
In order to generate and characterize Treg-of-B cells, Invitrogen ICOS antibody (eBioscience, C398.4 A) was used in flow cytometry on mouse samples (fig 4a). Sci Rep (2017) ncbi
hamsters monoclonal (C398.4A)
  • flow cytometry; mouse; loading ...
In order to assess the role of C1q in downregulating allergic inflammation, Invitrogen ICOS antibody (eBiosciences, C398.4A) was used in flow cytometry on mouse samples . Mucosal Immunol (2017) ncbi
hamsters monoclonal (C398.4A)
  • flow cytometry; mouse
In order to examine the contribution of Foxo1 to activated T cells, Invitrogen ICOS antibody (eBiocience, C398.4A) was used in flow cytometry on mouse samples . Nature (2016) ncbi
hamsters monoclonal (C398.4A)
  • flow cytometry; mouse; fig 6
Invitrogen ICOS antibody (eBiosciences, C398.4A) was used in flow cytometry on mouse samples (fig 6). Nat Immunol (2015) ncbi
hamsters monoclonal (C398.4A)
  • blocking or activating experiments; mouse; loading ...; fig 2a
In order to explore the relationship between ICOS signaling and FOXO1 in T follicular helper cells, Invitrogen ICOS antibody (eBioscience, C398.4A) was used in blocking or activating experiments on mouse samples (fig 2a). Immunity (2015) ncbi
hamsters monoclonal (C398.4A)
  • flow cytometry; mouse; fig 5
In order to show that the PTEN-mTORC2 axis maintains T regulatory cell stability and coordinates their control of effector responses, Invitrogen ICOS antibody (eBioscience, C398.4A) was used in flow cytometry on mouse samples (fig 5). Nat Immunol (2015) ncbi
hamsters monoclonal (C398.4A)
  • flow cytometry; mouse
In order to investigate the role of BTB-ZF factors in lymphoid effector programs, Invitrogen ICOS antibody (e-Bioscience, C398.4A) was used in flow cytometry on mouse samples . Nature (2012) ncbi
hamsters monoclonal (C398.4A)
  • flow cytometry; mouse; fig 1
In order to characterize and compare T helper 1 and 17 cells, Invitrogen ICOS antibody (eBiosciences, C398.4A) was used in flow cytometry on mouse samples (fig 1). J Leukoc Biol (2007) ncbi
hamsters monoclonal (C398.4A)
  • flow cytometry; Rhesus monkey; fig 7
In order to discuss the use of in vitro expanded polyclonal CD4+ T cells to treat SIV infection, Invitrogen ICOS antibody (eBioscience, C398.4A) was used in flow cytometry on Rhesus monkey samples (fig 7). J Med Primatol (2006) ncbi
hamsters monoclonal (C398.4A)
  • flow cytometry; mouse
In order to elucidate how Schistosoma mansoni suppresses T cell activation, Invitrogen ICOS antibody (eBiosciences, C3948.4A) was used in flow cytometry on mouse samples . J Immunol (2004) ncbi
Articles Reviewed
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  2. Sugiura D, Maruhashi T, Okazaki I, Shimizu K, Maeda T, Takemoto T, et al. Restriction of PD-1 function by cis-PD-L1/CD80 interactions is required for optimal T cell responses. Science. 2019;364:558-566 pubmed publisher
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  4. Binnewies M, Mujal A, Pollack J, Combes A, Hardison E, Barry K, et al. Unleashing Type-2 Dendritic Cells to Drive Protective Antitumor CD4+ T Cell Immunity. Cell. 2019;177:556-571.e16 pubmed publisher
  5. Kobayashi T, Voisin B, Kim D, Kennedy E, Jo J, Shih H, et al. Homeostatic Control of Sebaceous Glands by Innate Lymphoid Cells Regulates Commensal Bacteria Equilibrium. Cell. 2019;176:982-997.e16 pubmed publisher
  6. Li F, Zeng Z, Xing S, Gullicksrud J, Shan Q, Choi J, et al. Ezh2 programs TFH differentiation by integrating phosphorylation-dependent activation of Bcl6 and polycomb-dependent repression of p19Arf. Nat Commun. 2018;9:5452 pubmed publisher
  7. Shi J, Hou S, Fang Q, Liu X, Liu X, Qi H. PD-1 Controls Follicular T Helper Cell Positioning and Function. Immunity. 2018;49:264-274.e4 pubmed publisher
  8. Zhang C, Wang C, Jiang M, Gu C, Xiao J, Chen X, et al. Act1 is a negative regulator in T and B cells via direct inhibition of STAT3. Nat Commun. 2018;9:2745 pubmed publisher
  9. Cho S, Lee H, Yu I, Choi Y, Huang H, Hashemifar S, et al. Differential cell-intrinsic regulations of germinal center B and T cells by miR-146a and miR-146b. Nat Commun. 2018;9:2757 pubmed publisher
  10. Moysi E, Pallikkuth S, de Armas L, Gonzalez L, Ambrozak D, George V, et al. Altered immune cell follicular dynamics in HIV infection following influenza vaccination. J Clin Invest. 2018;128:3171-3185 pubmed publisher
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  17. Chien C, Yu H, Chen S, Chiang B. Characterization of c-Maf+Foxp3- Regulatory T Cells Induced by Repeated Stimulation of Antigen-Presenting B Cells. Sci Rep. 2017;7:46348 pubmed publisher
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  21. Serr I, Fürst R, Ott V, Scherm M, Nikolaev A, Gökmen F, et al. miRNA92a targets KLF2 and the phosphatase PTEN signaling to promote human T follicular helper precursors in T1D islet autoimmunity. Proc Natl Acad Sci U S A. 2016;113:E6659-E6668 pubmed
  22. Mascarell L, Airouche S, Berjont N, Gary C, Gueguen C, Fourcade G, et al. The regulatory dendritic cell marker C1q is a potent inhibitor of allergic inflammation. Mucosal Immunol. 2017;10:695-704 pubmed publisher
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  24. Johnston L, Hsu C, Krier Burris R, Chhiba K, Chien K, McKenzie A, et al. IL-33 Precedes IL-5 in Regulating Eosinophil Commitment and Is Required for Eosinophil Homeostasis. J Immunol. 2016;197:3445-3453 pubmed
  25. Lexmond W, Goettel J, Lyons J, Jacobse J, Deken M, Lawrence M, et al. FOXP3+ Tregs require WASP to restrain Th2-mediated food allergy. J Clin Invest. 2016;126:4030-4044 pubmed publisher
  26. Leong Y, Chen Y, Ong H, Wu D, Man K, Deléage C, et al. CXCR5(+) follicular cytotoxic T cells control viral infection in B cell follicles. Nat Immunol. 2016;17:1187-96 pubmed publisher
  27. Vaccari M, Gordon S, Fourati S, Schifanella L, Liyanage N, Cameron M, et al. Adjuvant-dependent innate and adaptive immune signatures of risk of SIVmac251 acquisition. Nat Med. 2016;22:762-70 pubmed publisher
  28. Bal S, Bernink J, Nagasawa M, Groot J, Shikhagaie M, Golebski K, et al. IL-1?, IL-4 and IL-12 control the fate of group 2 innate lymphoid cells in human airway inflammation in the lungs. Nat Immunol. 2016;17:636-45 pubmed publisher
  29. Zwang N, Zhang R, Germana S, Fan M, Hastings W, Cao A, et al. Selective Sparing of Human Tregs by Pharmacologic Inhibitors of the Phosphatidylinositol 3-Kinase and MEK Pathways. Am J Transplant. 2016;16:2624-38 pubmed publisher
  30. Leeth C, Racine J, Chapman H, Arpa B, Carrillo J, Carrascal J, et al. B-lymphocytes expressing an Ig specificity recognizing the pancreatic ß-cell autoantigen peripherin are potent contributors to type 1 diabetes development in NOD mice. Diabetes. 2016;65:1977-1987 pubmed publisher
  31. Llibre A, López Macías C, Marafioti T, Mehta H, Partridge A, Kanzig C, et al. LLT1 and CD161 Expression in Human Germinal Centers Promotes B Cell Activation and CXCR4 Downregulation. J Immunol. 2016;196:2085-94 pubmed publisher
  32. Luo C, Liao W, Dadi S, Toure A, Li M. Graded Foxo1 activity in Treg cells differentiates tumour immunity from spontaneous autoimmunity. Nature. 2016;529:532-6 pubmed publisher
  33. Vargas Inchaustegui D, Demers A, Shaw J, Kang G, Ball D, Tuero I, et al. Vaccine Induction of Lymph Node-Resident Simian Immunodeficiency Virus Env-Specific T Follicular Helper Cells in Rhesus Macaques. J Immunol. 2016;196:1700-10 pubmed publisher
  34. Kim J, Phan T, Nguyen V, Dinh Vu H, Zheng J, Yun M, et al. Salmonella typhimurium Suppresses Tumor Growth via the Pro-Inflammatory Cytokine Interleukin-1β. Theranostics. 2015;5:1328-42 pubmed publisher
  35. Miles B, Miller S, Folkvord J, Kimball A, Chamanian M, Meditz A, et al. Follicular regulatory T cells impair follicular T helper cells in HIV and SIV infection. Nat Commun. 2015;6:8608 pubmed publisher
  36. Choi Y, Gullicksrud J, Xing S, Zeng Z, Shan Q, Li F, et al. LEF-1 and TCF-1 orchestrate T(FH) differentiation by regulating differentiation circuits upstream of the transcriptional repressor Bcl6. Nat Immunol. 2015;16:980-90 pubmed publisher
  37. Lu K, Keppler S, Leithäuser F, Mattfeldt T, Castello A, Kostezka U, et al. Nck adaptor proteins modulate differentiation and effector function of T cells. J Leukoc Biol. 2015;98:301-11 pubmed publisher
  38. Stone E, Pepper M, Katayama C, Kerdiles Y, Lai C, Emslie E, et al. ICOS coreceptor signaling inactivates the transcription factor FOXO1 to promote Tfh cell differentiation. Immunity. 2015;42:239-251 pubmed publisher
  39. Nelson M, Kundimi S, Bowers J, Rogers C, Huff L, Schwartz K, et al. The inducible costimulator augments Tc17 cell responses to self and tumor tissue. J Immunol. 2015;194:1737-47 pubmed publisher
  40. Shrestha S, Yang K, Guy C, Vogel P, Neale G, Chi H. Treg cells require the phosphatase PTEN to restrain TH1 and TFH cell responses. Nat Immunol. 2015;16:178-87 pubmed publisher
  41. Xie L, Choudhury G, Winters A, Yang S, Jin K. Cerebral regulatory T cells restrain microglia/macrophage-mediated inflammatory responses via IL-10. Eur J Immunol. 2015;45:180-91 pubmed publisher
  42. Herati R, Reuter M, Dolfi D, Mansfield K, Aung H, Badwan O, et al. Circulating CXCR5+PD-1+ response predicts influenza vaccine antibody responses in young adults but not elderly adults. J Immunol. 2014;193:3528-37 pubmed publisher
  43. Hong J, Amancha P, Rogers K, Courtney C, Havenar Daughton C, Crotty S, et al. Early lymphoid responses and germinal center formation correlate with lower viral load set points and better prognosis of simian immunodeficiency virus infection. J Immunol. 2014;193:797-806 pubmed publisher
  44. Gros A, Robbins P, Yao X, Li Y, Turcotte S, Tran E, et al. PD-1 identifies the patient-specific CD8? tumor-reactive repertoire infiltrating human tumors. J Clin Invest. 2014;124:2246-59 pubmed publisher
  45. Mathew R, Seiler M, Scanlon S, Mao A, Constantinides M, Bertozzi Villa C, et al. BTB-ZF factors recruit the E3 ligase cullin 3 to regulate lymphoid effector programs. Nature. 2012;491:618-21 pubmed publisher
  46. Nakae S, Iwakura Y, Suto H, Galli S. Phenotypic differences between Th1 and Th17 cells and negative regulation of Th1 cell differentiation by IL-17. J Leukoc Biol. 2007;81:1258-68 pubmed
  47. Onlamoon N, Hudson K, Bryan P, Mayne A, Bonyhadi M, Berenson R, et al. Optimization of in vitro expansion of macaque CD4 T cells using anti-CD3 and co-stimulation for autotransfusion therapy. J Med Primatol. 2006;35:178-93 pubmed
  48. Smith P, Walsh C, Mangan N, Fallon R, Sayers J, McKenzie A, et al. Schistosoma mansoni worms induce anergy of T cells via selective up-regulation of programmed death ligand 1 on macrophages. J Immunol. 2004;173:1240-8 pubmed