This is a Validated Antibody Database (VAD) review about Rhesus mon.. CD86, based on 45 published articles (read how Labome selects the articles), using CD86 antibody in all methods. It is aimed to help Labome visitors find the most suited CD86 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
CD86 synonym: T-lymphocyte activation antigen CD86; CD86 antigen

BioLegend
mouse monoclonal (IT2.2)
  • flow cytometry; human; loading ...; fig 3c
BioLegend CD86 antibody (Biolegend, 305411) was used in flow cytometry on human samples (fig 3c). Cell Rep (2019) ncbi
mouse monoclonal (IT2.2)
  • flow cytometry; human; loading ...; fig 3c
BioLegend CD86 antibody (eBioscience, 305421) was used in flow cytometry on human samples (fig 3c). Cell (2019) ncbi
mouse monoclonal (IT2.2)
  • flow cytometry; human; loading ...; fig 1b
BioLegend CD86 antibody (BioLegend, IT2.2) was used in flow cytometry on human samples (fig 1b). Front Immunol (2018) ncbi
mouse monoclonal (IT2.2)
  • flow cytometry; human; loading ...; fig 5b
BioLegend CD86 antibody (BioLegend, IT2.2) was used in flow cytometry on human samples (fig 5b). J Immunol (2018) ncbi
mouse monoclonal (IT2.2)
  • flow cytometry; human; loading ...; fig 2c
BioLegend CD86 antibody (BioLegend, IT2.2) was used in flow cytometry on human samples (fig 2c). J Biol Chem (2018) ncbi
mouse monoclonal (IT2.2)
  • mass cytometry; human; loading ...; fig 2a
In order to investigate the immune composition of tumor microenvironment in hepatocellular carcinoma, BioLegend CD86 antibody (BioLegend, IT2.2) was used in mass cytometry on human samples (fig 2a). Proc Natl Acad Sci U S A (2017) ncbi
mouse monoclonal (IT2.2)
  • flow cytometry; human; loading ...; fig 4c
BioLegend CD86 antibody (BioLegend, 305423) was used in flow cytometry on human samples (fig 4c). J Clin Invest (2017) ncbi
mouse monoclonal (IT2.2)
  • flow cytometry; human; loading ...; fig s6a
In order to investigate the involvement of the TRIF pathway against the infection of Zika, Chikungunya, and Dengue viruses, BioLegend CD86 antibody (BioLegend, IT2.2) was used in flow cytometry on human samples (fig s6a). MBio (2017) ncbi
mouse monoclonal (IT2.2)
  • flow cytometry; human; fig 1b
In order to investigate the role of Vgamma9/Vdelta2 T cells in intestinal IL-22 production, BioLegend CD86 antibody (BioLegend, IT2.2) was used in flow cytometry on human samples (fig 1b). J Immunol (2017) ncbi
mouse monoclonal (IT2.2)
  • flow cytometry; human; 1:50; loading ...; fig s1d
BioLegend CD86 antibody (BioLegend, IT2.2) was used in flow cytometry on human samples at 1:50 (fig s1d). Nat Commun (2017) ncbi
mouse monoclonal (IT2.2)
  • flow cytometry; human; fig s4b
BioLegend CD86 antibody (BioLegend, IT 2.2) was used in flow cytometry on human samples (fig s4b). JCI Insight (2017) ncbi
mouse monoclonal (IT2.2)
  • flow cytometry; Rhesus monkey; loading ...
In order to study the efficacy of nanoparticle adjuvants for inducing protective immunity against simian immunodeficiency virus, BioLegend CD86 antibody (Biolegend, IT2.2) was used in flow cytometry on Rhesus monkey samples . J Virol (2017) ncbi
mouse monoclonal (IT2.2)
  • flow cytometry; human; loading ...; fig 1b
In order to investigate the roles of CD16+ monocytes in T-cell activation and B-cell responses in systemic lupus erythematosus, BioLegend CD86 antibody (Biolegend, 305431) was used in flow cytometry on human samples (fig 1b). Front Immunol (2016) ncbi
mouse monoclonal (IT2.2)
  • flow cytometry; human; loading ...; fig s9a
BioLegend CD86 antibody (BioLegend, IT2.2) was used in flow cytometry on human samples (fig s9a). PLoS Pathog (2016) ncbi
mouse monoclonal (IT2.2)
  • flow cytometry; human; loading ...
In order to determine which cells express CD83, BioLegend CD86 antibody (BioLegend, IT2.2) was used in flow cytometry on human samples . J Immunol (2016) ncbi
mouse monoclonal (IT2.2)
  • flow cytometry; human; loading ...; fig 4a
In order to identify a role for HIV p17 in the development of leukemia/lymphoma, BioLegend CD86 antibody (BioLegend, IT2.2) was used in flow cytometry on human samples (fig 4a). Proc Natl Acad Sci U S A (2016) ncbi
mouse monoclonal (IT2.2)
  • flow cytometry; human; loading ...; fig 2b
BioLegend CD86 antibody (BioLegend, 305406) was used in flow cytometry on human samples (fig 2b). Oncogene (2017) ncbi
mouse monoclonal (IT2.2)
  • flow cytometry; human; loading ...; fig 2a
BioLegend CD86 antibody (Biolegend, IT2.2) was used in flow cytometry on human samples (fig 2a). Eur J Immunol (2016) ncbi
mouse monoclonal (IT2.2)
  • flow cytometry; human; loading ...; fig 7c
BioLegend CD86 antibody (Biolegend, IT2.2) was used in flow cytometry on human samples (fig 7c). J Biol Chem (2016) ncbi
mouse monoclonal (IT2.2)
  • flow cytometry; human; loading ...; tbl 1
BioLegend CD86 antibody (BioLegend, IT2.2) was used in flow cytometry on human samples (tbl 1). J Immunol (2016) ncbi
mouse monoclonal (IT2.2)
  • flow cytometry; human; fig s6b
In order to test if AML patients treated decitabine have induced expression of cancer testis antigens, BioLegend CD86 antibody (BioLegend, IT2.2) was used in flow cytometry on human samples (fig s6b). Oncotarget (2016) ncbi
mouse monoclonal (IT2.2)
  • flow cytometry; human; fig 1
BioLegend CD86 antibody (BioLegend, 305405) was used in flow cytometry on human samples (fig 1). Sci Rep (2015) ncbi
mouse monoclonal (IT2.2)
  • flow cytometry; human; fig 4
BioLegend CD86 antibody (Biolegend, 305420) was used in flow cytometry on human samples (fig 4). PLoS ONE (2015) ncbi
mouse monoclonal (IT2.2)
  • flow cytometry; human; fig 6
BioLegend CD86 antibody (Biolegend, IT2.2) was used in flow cytometry on human samples (fig 6). PLoS Pathog (2015) ncbi
mouse monoclonal (IT2.2)
  • flow cytometry; equine; loading ...; fig 4
BioLegend CD86 antibody (Biolegend, IT2.2) was used in flow cytometry on equine samples (fig 4). PLoS ONE (2015) ncbi
mouse monoclonal (IT2.2)
  • flow cytometry; human; fig 3
In order to study human cord blood and bone marrow for restricted dendritic cell and monocyte progenitors, BioLegend CD86 antibody (Biolegend, IT2.2) was used in flow cytometry on human samples (fig 3). J Exp Med (2015) ncbi
mouse monoclonal (IT2.2)
  • flow cytometry; human; loading ...; fig 9a
In order to explore a macrophage TLR9-BTK-calcineurin-NFAT signaling pathway involved in impair fungal immunity, BioLegend CD86 antibody (Biolegend, 305425) was used in flow cytometry on human samples (fig 9a). EMBO Mol Med (2015) ncbi
mouse monoclonal (IT2.2)
  • flow cytometry; human; fig 7
BioLegend CD86 antibody (Biolegend, IT2.2) was used in flow cytometry on human samples (fig 7). Toxicol Sci (2015) ncbi
mouse monoclonal (IT2.2)
  • flow cytometry; mouse
  • flow cytometry; human
BioLegend CD86 antibody (BioLegend, IT2.2) was used in flow cytometry on mouse samples and in flow cytometry on human samples . Hum Immunol (2014) ncbi
mouse monoclonal (IT2.2)
  • flow cytometry; human; fig 1
BioLegend CD86 antibody (Biolegend, IT2.2) was used in flow cytometry on human samples (fig 1). J Infect Dis (2015) ncbi
mouse monoclonal (IT2.2)
  • flow cytometry; human; fig 4
BioLegend CD86 antibody (BioLegend, IT2.2) was used in flow cytometry on human samples (fig 4). Infect Immun (2015) ncbi
mouse monoclonal (IT2.2)
  • flow cytometry; human
BioLegend CD86 antibody (Biolegend, IT2.2) was used in flow cytometry on human samples . Eur J Immunol (2015) ncbi
mouse monoclonal (IT2.2)
  • flow cytometry; human
BioLegend CD86 antibody (BioLegend, IT2.2) was used in flow cytometry on human samples . PLoS ONE (2014) ncbi
mouse monoclonal (IT2.2)
  • flow cytometry; human
BioLegend CD86 antibody (Biolegend, IT2.2) was used in flow cytometry on human samples . J Hepatol (2015) ncbi
mouse monoclonal (IT2.2)
  • blocking or activating experiments; human; 10 ug/ml
BioLegend CD86 antibody (BioLegend, IT2.2) was used in blocking or activating experiments on human samples at 10 ug/ml. Immunology (2014) ncbi
mouse monoclonal (IT2.2)
  • flow cytometry; human
BioLegend CD86 antibody (BioLegend, IT2.2) was used in flow cytometry on human samples . J Leukoc Biol (2014) ncbi
mouse monoclonal (IT2.2)
  • flow cytometry; human
BioLegend CD86 antibody (BioLegend, IT2.2) was used in flow cytometry on human samples . J Immunol (2014) ncbi
mouse monoclonal (IT2.2)
  • flow cytometry; human
BioLegend CD86 antibody (BioLegend, IT2.2) was used in flow cytometry on human samples . Clin Cancer Res (2014) ncbi
mouse monoclonal (IT2.2)
  • flow cytometry; human
BioLegend CD86 antibody (BioLegend, IT2.2) was used in flow cytometry on human samples . Blood (2014) ncbi
mouse monoclonal (IT2.2)
  • flow cytometry; human
In order to examine various DC after flu vaccination, BioLegend CD86 antibody (Biolegend, IT2.2) was used in flow cytometry on human samples . Immunol Invest (2014) ncbi
mouse monoclonal (IT2.2)
  • flow cytometry; human
In order to determine the presence, frequency, association to other immune parameters, and functional properties of circulating CD14(+) cells lacking HLA-DR expression in patients with untreated chronic lymphocytic leukemia, BioLegend CD86 antibody (Biolegend, IT2.2) was used in flow cytometry on human samples . Blood (2014) ncbi
mouse monoclonal (IT2.2)
  • flow cytometry; mouse
BioLegend CD86 antibody (BioLegend, IT2.2) was used in flow cytometry on mouse samples . PLoS ONE (2014) ncbi
mouse monoclonal (IT2.2)
  • flow cytometry; human; loading ...; fig 4d
In order to test if hip fracture and depressive symptoms had additive effects upon the aged immune system, BioLegend CD86 antibody (BioLegend, IT2.2) was used in flow cytometry on human samples (fig 4d). Exp Gerontol (2014) ncbi
mouse monoclonal (IT2.2)
  • flow cytometry; human; loading ...; fig 2a
In order to assess how different concentrations of IFN-gamma affect dendritic cells, BioLegend CD86 antibody (BioLegend, IT2.2) was used in flow cytometry on human samples (fig 2a). J Leukoc Biol (2014) ncbi
mouse monoclonal (IT2.2)
  • flow cytometry; human
BioLegend CD86 antibody (Biolegend, clone IT2.2) was used in flow cytometry on human samples . J Immunol Methods (2009) ncbi
Articles Reviewed
  1. Celis Gutierrez J, Blattmann P, Zhai Y, Jarmuzynski N, Ruminski K, Gregoire C, et al. Quantitative Interactomics in Primary T Cells Provides a Rationale for Concomitant PD-1 and BTLA Coinhibitor Blockade in Cancer Immunotherapy. Cell Rep. 2019;27:3315-3330.e7 pubmed publisher
  2. Georgouli M, Herraiz C, Crosas Molist E, Fanshawe B, Maiques O, Perdrix A, et al. Regional Activation of Myosin II in Cancer Cells Drives Tumor Progression via a Secretory Cross-Talk with the Immune Microenvironment. Cell. 2019;176:757-774.e23 pubmed publisher
  3. Richardson J, Armbruster N, Günter M, Henes J, Autenrieth S. Staphylococcus aureus PSM Peptides Modulate Human Monocyte-Derived Dendritic Cells to Prime Regulatory T Cells. Front Immunol. 2018;9:2603 pubmed publisher
  4. Otsuka Y, Watanabe E, Shinya E, Okura S, Saeki H, Geijtenbeek T, et al. Differentiation of Langerhans Cells from Monocytes and Their Specific Function in Inducing IL-22-Specific Th Cells. J Immunol. 2018;201:3006-3016 pubmed publisher
  5. Melo Gonzalez F, Fenton T, Forss C, Smedley C, Goenka A, MacDonald A, et al. Intestinal mucin activates human dendritic cells and IL-8 production in a glycan-specific manner. J Biol Chem. 2018;293:8543-8553 pubmed publisher
  6. Chew V, Lai L, Pan L, Lim C, Li J, Ong R, et al. Delineation of an immunosuppressive gradient in hepatocellular carcinoma using high-dimensional proteomic and transcriptomic analyses. Proc Natl Acad Sci U S A. 2017;114:E5900-E5909 pubmed publisher
  7. Watanabe R, Shirai T, Namkoong H, Zhang H, Berry G, Wallis B, et al. Pyruvate controls the checkpoint inhibitor PD-L1 and suppresses T cell immunity. J Clin Invest. 2017;127:2725-2738 pubmed publisher
  8. Pryke K, Abraham J, Sali T, Gall B, Archer I, Liu A, et al. A Novel Agonist of the TRIF Pathway Induces a Cellular State Refractory to Replication of Zika, Chikungunya, and Dengue Viruses. MBio. 2017;8: pubmed publisher
  9. Tyler C, McCarthy N, Lindsay J, Stagg A, Moser B, Eberl M. Antigen-Presenting Human γδ T Cells Promote Intestinal CD4+ T Cell Expression of IL-22 and Mucosal Release of Calprotectin. J Immunol. 2017;198:3417-3425 pubmed publisher
  10. Smith N, Pietrancosta N, Davidson S, Dutrieux J, Chauveau L, Cutolo P, et al. Natural amines inhibit activation of human plasmacytoid dendritic cells through CXCR4 engagement. Nat Commun. 2017;8:14253 pubmed publisher
  11. Martin Gayo E, Cronin J, Hickman T, Ouyang Z, Lindqvist M, Kolb K, et al. Circulating CXCR5+CXCR3+PD-1lo Tfh-like cells in HIV-1 controllers with neutralizing antibody breadth. JCI Insight. 2017;2:e89574 pubmed publisher
  12. Kasturi S, Kozlowski P, Nakaya H, Burger M, Russo P, Pham M, et al. Adjuvanting a Simian Immunodeficiency Virus Vaccine with Toll-Like Receptor Ligands Encapsulated in Nanoparticles Induces Persistent Antibody Responses and Enhanced Protection in TRIM5α Restrictive Macaques. J Virol. 2017;91: pubmed publisher
  13. Zhu H, Hu F, Sun X, Zhang X, Zhu L, Liu X, et al. CD16+ Monocyte Subset Was Enriched and Functionally Exacerbated in Driving T-Cell Activation and B-Cell Response in Systemic Lupus Erythematosus. Front Immunol. 2016;7:512 pubmed
  14. Tomic A, Varanasi P, Golemac M, Malic S, Riese P, Borst E, et al. Activation of Innate and Adaptive Immunity by a Recombinant Human Cytomegalovirus Strain Expressing an NKG2D Ligand. PLoS Pathog. 2016;12:e1006015 pubmed publisher
  15. Ju X, Silveira P, Hsu W, Elgundi Z, Alingcastre R, Verma N, et al. The Analysis of CD83 Expression on Human Immune Cells Identifies a Unique CD83+-Activated T Cell Population. J Immunol. 2016;197:4613-4625 pubmed
  16. Carroll V, Lafferty M, Marchionni L, Bryant J, Gallo R, Garzino Demo A. Expression of HIV-1 matrix protein p17 and association with B-cell lymphoma in HIV-1 transgenic mice. Proc Natl Acad Sci U S A. 2016;113:13168-13173 pubmed
  17. Deng Y, Cheng J, Fu B, Liu W, Chen G, Zhang Q, et al. Hepatic carcinoma-associated fibroblasts enhance immune suppression by facilitating the generation of myeloid-derived suppressor cells. Oncogene. 2017;36:1090-1101 pubmed publisher
  18. Cheng W, van Asten S, Burns L, Evans H, Walter G, Hashim A, et al. Periodontitis-associated pathogens P. gingivalis and A. actinomycetemcomitans activate human CD14(+) monocytes leading to enhanced Th17/IL-17 responses. Eur J Immunol. 2016;46:2211-21 pubmed publisher
  19. Zanetti S, Ziblat A, Torres N, Zwirner N, Bouzat C. Expression and Functional Role of ?7 Nicotinic Receptor in Human Cytokine-stimulated Natural Killer (NK) Cells. J Biol Chem. 2016;291:16541-52 pubmed publisher
  20. Li H, Borrego F, Nagata S, Tolnay M. Fc Receptor-like 5 Expression Distinguishes Two Distinct Subsets of Human Circulating Tissue-like Memory B Cells. J Immunol. 2016;196:4064-74 pubmed publisher
  21. Srivastava P, Paluch B, Matsuzaki J, James S, Collamat Lai G, Blagitko Dorfs N, et al. Induction of cancer testis antigen expression in circulating acute myeloid leukemia blasts following hypomethylating agent monotherapy. Oncotarget. 2016;7:12840-56 pubmed publisher
  22. Yamagishi M, Katano H, Hishima T, Shimoyama T, Ota Y, Nakano K, et al. Coordinated loss of microRNA group causes defenseless signaling in malignant lymphoma. Sci Rep. 2015;5:17868 pubmed publisher
  23. McCausland M, Juchnowski S, Zidar D, Kuritzkes D, Andrade A, Sieg S, et al. Altered Monocyte Phenotype in HIV-1 Infection Tends to Normalize with Integrase-Inhibitor-Based Antiretroviral Therapy. PLoS ONE. 2015;10:e0139474 pubmed publisher
  24. Rancan C, Schirrmann L, Hüls C, Zeidler R, Moosmann A. Latent Membrane Protein LMP2A Impairs Recognition of EBV-Infected Cells by CD8+ T Cells. PLoS Pathog. 2015;11:e1004906 pubmed publisher
  25. Meulenbroeks C, van der Lugt J, van der Meide N, Willemse T, Rutten V, Zaiss D. Allergen-Specific Cytokine Polarization Protects Shetland Ponies against Culicoides obsoletus-Induced Insect Bite Hypersensitivity. PLoS ONE. 2015;10:e0122090 pubmed publisher
  26. Lee J, Breton G, Oliveira T, Zhou Y, Aljoufi A, PUHR S, et al. Restricted dendritic cell and monocyte progenitors in human cord blood and bone marrow. J Exp Med. 2015;212:385-99 pubmed publisher
  27. Herbst S, Shah A, Mazon Moya M, Marzola V, Jensen B, Reed A, et al. Phagocytosis-dependent activation of a TLR9-BTK-calcineurin-NFAT pathway co-ordinates innate immunity to Aspergillus fumigatus. EMBO Mol Med. 2015;7:240-58 pubmed publisher
  28. Phadnis Moghe A, Crawford R, Kaminski N. Suppression of human B cell activation by 2,3,7,8-tetrachlorodibenzo-p-dioxin involves altered regulation of B cell lymphoma-6. Toxicol Sci. 2015;144:39-50 pubmed publisher
  29. Cousens L, Najafian N, Martin W, De Groot A. Tregitope: Immunomodulation powerhouse. Hum Immunol. 2014;75:1139-46 pubmed publisher
  30. Boltjes A, van Montfoort N, Biesta P, Op den Brouw M, Kwekkeboom J, van der Laan L, et al. Kupffer cells interact with hepatitis B surface antigen in vivo and in vitro, leading to proinflammatory cytokine production and natural killer cell function. J Infect Dis. 2015;211:1268-78 pubmed publisher
  31. Brummelman J, Veerman R, Hamstra H, Deuss A, Schuijt T, Sloots A, et al. Bordetella pertussis naturally occurring isolates with altered lipooligosaccharide structure fail to fully mature human dendritic cells. Infect Immun. 2015;83:227-38 pubmed publisher
  32. Ziblat A, Domaica C, Spallanzani R, Iraolagoitia X, Rossi L, Avila D, et al. IL-27 stimulates human NK-cell effector functions and primes NK cells for IL-18 responsiveness. Eur J Immunol. 2015;45:192-202 pubmed publisher
  33. Škrnjug I, Guzmán C, Rueckert C, Ruecker C. Cyclic GMP-AMP displays mucosal adjuvant activity in mice. PLoS ONE. 2014;9:e110150 pubmed publisher
  34. Spaan M, Kreefft K, de Graav G, Brouwer W, de Knegt R, ten Kate F, et al. CD4+ CXCR5+ T cells in chronic HCV infection produce less IL-21, yet are efficient at supporting B cell responses. J Hepatol. 2015;62:303-10 pubmed publisher
  35. Preciado Llanes L, Wing J, Foster R, Carlring J, Lees A, Read R, et al. Contact dependent suppression of CD4 T cell activation and proliferation by B cells activated through IgD cross-linking. Immunology. 2014;: pubmed publisher
  36. Chao Y, Kaliaperumal N, Chretien A, Tang S, Lee B, Poidinger M, et al. Human plasmacytoid dendritic cells regulate IFN-α production through activation-induced splicing of IL-18Rα. J Leukoc Biol. 2014;96:1037-46 pubmed publisher
  37. Royle C, Graham D, Sharma S, Fuchs D, Boasso A. HIV-1 and HIV-2 differentially mature plasmacytoid dendritic cells into IFN-producing cells or APCs. J Immunol. 2014;193:3538-48 pubmed publisher
  38. Koido S, Homma S, Okamoto M, Takakura K, Mori M, Yoshizaki S, et al. Treatment with chemotherapy and dendritic cells pulsed with multiple Wilms' tumor 1 (WT1)-specific MHC class I/II-restricted epitopes for pancreatic cancer. Clin Cancer Res. 2014;20:4228-39 pubmed publisher
  39. Lee Chang C, Bodogai M, Moritoh K, Olkhanud P, Chan A, Croft M, et al. Accumulation of 4-1BBL+ B cells in the elderly induces the generation of granzyme-B+ CD8+ T cells with potential antitumor activity. Blood. 2014;124:1450-9 pubmed publisher
  40. Kobie J, Treanor J, Ritchlin C. Transient decrease in human peripheral blood myeloid dendritic cells following influenza vaccination correlates with induction of serum antibody. Immunol Invest. 2014;43:606-15 pubmed publisher
  41. Jitschin R, Braun M, Büttner M, Dettmer Wilde K, Bricks J, Berger J, et al. CLL-cells induce IDOhi CD14+HLA-DRlo myeloid-derived suppressor cells that inhibit T-cell responses and promote TRegs. Blood. 2014;124:750-60 pubmed publisher
  42. Skrnjug I, Rueckert C, Libanova R, Lienenklaus S, Weiss S, Guzman C. The mucosal adjuvant cyclic di-AMP exerts immune stimulatory effects on dendritic cells and macrophages. PLoS ONE. 2014;9:e95728 pubmed publisher
  43. Duggal N, Beswetherick A, Upton J, Hampson P, Phillips A, Lord J. Depressive symptoms in hip fracture patients are associated with reduced monocyte superoxide production. Exp Gerontol. 2014;54:27-34 pubmed publisher
  44. Svajger U, Obermajer N, Jeras M. IFN-?-rich environment programs dendritic cells toward silencing of cytotoxic immune responses. J Leukoc Biol. 2014;95:33-46 pubmed publisher
  45. Wang J, Kobie J, Zhang L, Cochran M, Mosmann T, Ritchlin C, et al. An 11-color flow cytometric assay for identifying, phenotyping, and assessing endocytic ability of peripheral blood dendritic cell subsets in a single platform. J Immunol Methods. 2009;341:106-16 pubmed publisher