This is a Validated Antibody Database (VAD) review about Chinese ha.. Epas1, based on 9 published articles (read how Labome selects the articles), using Epas1 antibody in all methods. It is aimed to help Labome visitors find the most suited Epas1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Epas1 synonym: endothelial PAS domain-containing protein 1; Endothelial PAS domain-containing protein 1

Invitrogen
rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig 6b
In order to find the specific gene signature related to iron metabolism consisting of genes regulating iron uptake, mitochondrial FeS cluster biogenesis and hypoxic response, Invitrogen Epas1 antibody (ThermoScientific, PA116510) was used in western blot on human samples at 1:1000 (fig 6b). Oncotarget (2017) ncbi
rabbit polyclonal
  • immunohistochemistry; mouse; fig s2a
In order to analyze the suppression of soft tissue sarcoma growth due to epigenetic re-expression of HIF-2 alpha, Invitrogen Epas1 antibody (ThermoPierce, PA1-16510) was used in immunohistochemistry on mouse samples (fig s2a). Nat Commun (2016) ncbi
rabbit polyclonal
  • western blot; human; 1:1000; fig 4
In order to investigate factors that control PHD1 activity, Invitrogen Epas1 antibody (Thermo Scientific, PA1-16510) was used in western blot on human samples at 1:1000 (fig 4). J Cell Sci (2016) ncbi
rabbit polyclonal
  • western blot; human; fig 1a
In order to report that expression of HIF2alpha is regulated by the deubiquitylase Cezanne in an E2F1-dependent manner, Invitrogen Epas1 antibody (Thermo Scientific, PA1-16510) was used in western blot on human samples (fig 1a). J Cell Sci (2015) ncbi
rabbit polyclonal
  • western blot; human; 1:1000
In order to study the effect of allopurinol treatment during hypoxia, Invitrogen Epas1 antibody (Thermo Fisher Scientific, PA1-16510) was used in western blot on human samples at 1:1000. PLoS ONE (2015) ncbi
rabbit polyclonal
  • western blot; human; fig 2
In order to identify PITX1 as a key specificity factor for HIF-1alpha dependent gene expression, Invitrogen Epas1 antibody (Thermo Scientific, PA1-16510) was used in western blot on human samples (fig 2). Cell Cycle (2014) ncbi
rabbit polyclonal
  • western blot; mouse; 1:500; fig 2
In order to study vascular endothelial growth factor signaling in mice infected with Plasmodium berghei ANKA, Invitrogen Epas1 antibody (Thermo Scientific, PA1-16510) was used in western blot on mouse samples at 1:500 (fig 2). Front Immunol (2014) ncbi
rabbit polyclonal
  • western blot; rat; 1:200
In order to study HIF-1alpha mediated metabolic switching and mitochondrial remodeling in bladder outlet obstruction, Invitrogen Epas1 antibody (Thermo Scientific, PA1-16510) was used in western blot on rat samples at 1:200. Lab Invest (2014) ncbi
rabbit polyclonal
  • western blot; human
In order to study the role of chromatin remodeling in the hypoxia response, Invitrogen Epas1 antibody (Thermo Scientific, PA1-16510) was used in western blot on human samples . Mol Biol Cell (2011) ncbi
Articles Reviewed
  1. Rychtarčíková Z, Lettlova S, Tomkova V, Korenkova V, Langerova L, Simonova E, et al. Tumor-initiating cells of breast and prostate origin show alterations in the expression of genes related to iron metabolism. Oncotarget. 2017;8:6376-6398 pubmed publisher
  2. Nakazawa M, Eisinger Mathason T, Sadri N, Ochocki J, Gade T, Amin R, et al. Epigenetic re-expression of HIF-2α suppresses soft tissue sarcoma growth. Nat Commun. 2016;7:10539 pubmed publisher
  3. Ortmann B, Bensaddek D, Carvalhal S, Moser S, Mudie S, Griffis E, et al. CDK-dependent phosphorylation of PHD1 on serine 130 alters its substrate preference in cells. J Cell Sci. 2016;129:191-205 pubmed publisher
  4. Moniz S, Bandarra D, Biddlestone J, Campbell K, Komander D, Bremm A, et al. Cezanne regulates E2F1-dependent HIF2α expression. J Cell Sci. 2015;128:3082-93 pubmed publisher
  5. Sun Y, George J, Rocha S. Dose-dependent effects of allopurinol on human foreskin fibroblast cells and human umbilical vein endothelial cells under hypoxia. PLoS ONE. 2015;10:e0123649 pubmed publisher
  6. Mudie S, Bandarra D, Batie M, Biddlestone J, Moniz S, Ortmann B, et al. PITX1, a specificity determinant in the HIF-1α-mediated transcriptional response to hypoxia. Cell Cycle. 2014;13:3878-91 pubmed publisher
  7. Hempel C, Hoyer N, Kildemoes A, Jendresen C, Kurtzhals J. Systemic and Cerebral Vascular Endothelial Growth Factor Levels Increase in Murine Cerebral Malaria along with Increased Calpain and Caspase Activity and Can be Reduced by Erythropoietin Treatment. Front Immunol. 2014;5:291 pubmed publisher
  8. Ekman M, Uvelius B, Albinsson S, Swärd K. HIF-mediated metabolic switching in bladder outlet obstruction mitigates the relaxing effect of mitochondrial inhibition. Lab Invest. 2014;94:557-68 pubmed publisher
  9. Melvin A, Mudie S, Rocha S. The chromatin remodeler ISWI regulates the cellular response to hypoxia: role of FIH. Mol Biol Cell. 2011;22:4171-81 pubmed publisher