This is a Validated Antibody Database (VAD) review about Chinese ha.. Ap2a1, based on 8 published articles (read how Labome selects the articles), using Ap2a1 antibody in all methods. It is aimed to help Labome visitors find the most suited Ap2a1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Ap2a1 synonym: AP-2 complex subunit alpha-1; adaptor protein complex AP-2, alpha 1 subunit; adaptor related protein complex 2 alpha 1 subunit

Invitrogen
mouse monoclonal (AP6)
  • immunocytochemistry; human; loading ...; fig 3d
In order to investigate the adhesion structures in 3-D cell migration, Invitrogen Ap2a1 antibody (ThermoFisher, AP6) was used in immunocytochemistry on human samples (fig 3d). Science (2017) ncbi
mouse monoclonal (AP6)
  • immunocytochemistry; human; fig 2b
  • western blot; human; fig 1b
  • immunocytochemistry; pig; loading ...; fig 5d
  • western blot; pig; loading ...; fig 5a
In order to study amyloid precursor protein Tyr phosphorylation in mouse model of Alzheimer's disease, Invitrogen Ap2a1 antibody (Thermo Fisher, MA1-064) was used in immunocytochemistry on human samples (fig 2b), in western blot on human samples (fig 1b), in immunocytochemistry on pig samples (fig 5d) and in western blot on pig samples (fig 5a). Front Mol Neurosci (2017) ncbi
mouse monoclonal (AP6)
  • immunocytochemistry; human; loading ...; fig 2d
In order to assess the effect of three alpha-tubulin acetyltransferase 1-specific shRNAs on proliferation and morphology in HeLa and A549 cell lines, Invitrogen Ap2a1 antibody (Thermo Fisher, MA1-064) was used in immunocytochemistry on human samples (fig 2d). Cell Death Discov (2016) ncbi
mouse monoclonal (AP6)
  • immunocytochemistry; human; fig s5
In order to monitor the interaction beteween integrin alpha chain and AP2 and how selective integrin endocytosis drives the interaction, Invitrogen Ap2a1 antibody (Pierce, MA1-064) was used in immunocytochemistry on human samples (fig s5). Nat Struct Mol Biol (2016) ncbi
mouse monoclonal (AP6)
  • immunocytochemistry; rat; fig 4
In order to characterize inhibition of clathrin-mediated and bulk endocytosis by synaptotagmin-11, Invitrogen Ap2a1 antibody (Thermo Scientific, MA1-064) was used in immunocytochemistry on rat samples (fig 4). EMBO Rep (2016) ncbi
mouse monoclonal (AP6)
  • immunocytochemistry; African green monkey; fig s2d
  • western blot; human; fig s1f
In order to identify and characterize a new endocytic route that is called fast endophilin-mediated endocytosis, Invitrogen Ap2a1 antibody (Thermo, MA1-064) was used in immunocytochemistry on African green monkey samples (fig s2d) and in western blot on human samples (fig s1f). Nature (2015) ncbi
mouse monoclonal (AP6)
  • immunocytochemistry; mouse; fig 2
In order to study the off-target activity of dynamin inhibitors using cells deleted for dynamins 1-3, Invitrogen Ap2a1 antibody (Affinity Bioreagents, AP6) was used in immunocytochemistry on mouse samples (fig 2). J Cell Sci (2013) ncbi
mouse monoclonal (AP6)
  • immunocytochemistry; human; fig 3
In order to develop an array-based multiplexed analysis of signaling pathways, Invitrogen Ap2a1 antibody (Affinity BioReagents, MA1-064) was used in immunocytochemistry on human samples (fig 3). Mol Cell Proteomics (2007) ncbi
Articles Reviewed
  1. Elkhatib N, Bresteau E, Baschieri F, Rioja A, van Niel G, Vassilopoulos S, et al. Tubular clathrin/AP-2 lattices pinch collagen fibers to support 3D cell migration. Science. 2017;356: pubmed publisher
  2. Poulsen E, Iannuzzi F, Rasmussen H, Maier T, Enghild J, Jørgensen A, et al. An Aberrant Phosphorylation of Amyloid Precursor Protein Tyrosine Regulates Its Trafficking and the Binding to the Clathrin Endocytic Complex in Neural Stem Cells of Alzheimer's Disease Patients. Front Mol Neurosci. 2017;10:59 pubmed publisher
  3. Chien J, Tsen S, Chien C, Liu H, Tung C, Lin C. ?TAT1 downregulation induces mitotic catastrophe in HeLa and A549 cells. Cell Death Discov. 2016;2:16006 pubmed publisher
  4. De Franceschi N, Arjonen A, Elkhatib N, Denessiouk K, Wrobel A, Wilson T, et al. Selective integrin endocytosis is driven by interactions between the integrin α-chain and AP2. Nat Struct Mol Biol. 2016;23:172-9 pubmed publisher
  5. Wang C, Wang Y, Hu M, Chai Z, Wu Q, Huang R, et al. Synaptotagmin-11 inhibits clathrin-mediated and bulk endocytosis. EMBO Rep. 2016;17:47-63 pubmed publisher
  6. Boucrot E, Ferreira A, Almeida Souza L, Debard S, Vallis Y, Howard G, et al. Endophilin marks and controls a clathrin-independent endocytic pathway. Nature. 2015;517:460-5 pubmed publisher
  7. Park R, Shen H, Liu L, Liu X, Ferguson S, De Camilli P. Dynamin triple knockout cells reveal off target effects of commonly used dynamin inhibitors. J Cell Sci. 2013;126:5305-12 pubmed publisher
  8. Zanardi A, Giorgetti L, Botrugno O, Minucci S, Milani P, Pelicci P, et al. Immunocell-array for molecular dissection of multiple signaling pathways in mammalian cells. Mol Cell Proteomics. 2007;6:939-47 pubmed