This is a Validated Antibody Database (VAD) review about Caenorhabd.. mpk 1, based on 28 published articles (read how Labome selects the articles), using mpk 1 antibody in all methods. It is aimed to help Labome visitors find the most suited mpk 1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
mpk 1 synonym: Mitogen-activated protein kinase mpk-1

Invitrogen
rabbit polyclonal
  • western blot; human; loading ...; fig 1d
In order to characterize a new specific pharmacological hematopoietic cell kinase inhibitor, Invitrogen mpk 1 antibody (Invitrogen, 44-680G) was used in western blot on human samples (fig 1d). Biochim Biophys Acta Mol Basis Dis (2017) ncbi
rabbit polyclonal
  • western blot; human; loading ...; fig 1b
In order to compare dabrafenib-resistant and -sensitive BRAF-mutant human melanoma cell lines, Invitrogen mpk 1 antibody (Invitrogen, 44-680G) was used in western blot on human samples (fig 1b). Int J Oncol (2016) ncbi
rabbit polyclonal
  • western blot; mouse; loading ...; fig 5e
  • western blot; human; loading ...; fig s3b
In order to discover that WNK1 kinase regulates integrin-mediated adhesion and T cell migration, Invitrogen mpk 1 antibody (Life Technologies, 44-680G) was used in western blot on mouse samples (fig 5e) and in western blot on human samples (fig s3b). Nat Immunol (2016) ncbi
rabbit polyclonal
  • western blot; human; fig 4
In order to determine facilitation of chemoresistance and cancer proliferation by Haem-dependent dimerization of PGRMC1/Sigma-2 receptor, Invitrogen mpk 1 antibody (Invitrogen, 44680G) was used in western blot on human samples (fig 4). Nat Commun (2016) ncbi
rabbit polyclonal
  • immunohistochemistry - paraffin section; human; fig 3
  • western blot; human; fig 1
In order to learn how oncogene addiction can be broken in tumors with MET amplification by the Anti-c-Met monoclonal antibody ABT-700, Invitrogen mpk 1 antibody (Invitrogen, 44680G) was used in immunohistochemistry - paraffin section on human samples (fig 3) and in western blot on human samples (fig 1). BMC Cancer (2016) ncbi
rabbit polyclonal
  • western blot; rat; fig 5
In order to investigate the role of neuron-enriched Na(+)/H(+) exchanger NHE5, Invitrogen mpk 1 antibody (Invitrogen, 44-680G) was used in western blot on rat samples (fig 5). Mol Biol Cell (2016) ncbi
rabbit polyclonal
  • western blot; human; 1:1000; fig 3
In order to test if DEHP affects MMP-2 or MMP-9 expression in vascular smooth muscle cells, Invitrogen mpk 1 antibody (Invitrogen, 44680G) was used in western blot on human samples at 1:1000 (fig 3). Int J Mol Sci (2015) ncbi
rabbit polyclonal
  • western blot; human; fig 3
In order to study how all-trans retinoic acid modulates the ERK signaling pathway, Invitrogen mpk 1 antibody (Thermo Fisher Scientific, 44-680G) was used in western blot on human samples (fig 3). Biomed Res Int (2015) ncbi
rabbit polyclonal
  • western blot; human; fig 1
In order to show that inhibition of the oxidative arm of the pentose phosphate pathway is required for antimalarial-mediated apoptosis, Invitrogen mpk 1 antibody (Invitrogen, 44-680G) was used in western blot on human samples (fig 1). Oncogene (2016) ncbi
rabbit polyclonal
  • western blot; human; 1:1000
In order to test if NBDHEX and MC3181 have antitumor activity against melanoma cells resistant to vemurafenib, Invitrogen mpk 1 antibody (Invitrogen, 44680G) was used in western blot on human samples at 1:1000. Biochem Pharmacol (2015) ncbi
rabbit polyclonal
  • immunocytochemistry; rat; fig 1
In order to describe a method for the preparation, fixation, and fluorescence analysis of in vitro cultivated metacestode vesicles from E. multilocularis, Invitrogen mpk 1 antibody (Life Technologies, 44680G) was used in immunocytochemistry on rat samples (fig 1). PLoS ONE (2015) ncbi
rabbit polyclonal
  • western blot; mouse; 1:2000; fig 5b
In order to uncover a role for ATG12-ATG3 in late endosome function that is distinct from autophagy, Invitrogen mpk 1 antibody (Biosource, 44-680G) was used in western blot on mouse samples at 1:2000 (fig 5b). Nat Cell Biol (2015) ncbi
rabbit polyclonal
  • western blot; human; fig 4
In order to elucidate the tumor suppressor function of BTG3, Invitrogen mpk 1 antibody (Invitrogen Life Technologies, 44680G) was used in western blot on human samples (fig 4). Cell Death Dis (2015) ncbi
rabbit monoclonal (K.913.4)
  • immunohistochemistry - paraffin section; zebrafish
  • western blot; zebrafish
In order to show that H2O2 acts via MAPK signaling for heart regeneration in adult zebrafish, Invitrogen mpk 1 antibody (Pierce, MA5-15134) was used in immunohistochemistry - paraffin section on zebrafish samples and in western blot on zebrafish samples . Cell Res (2014) ncbi
rabbit polyclonal
  • immunohistochemistry; human; 1:50; fig 6
  • western blot; human; 1:1000; fig 4
In order to assess the role of the MEK1/2-ERK1/2 signaling pathway in the pathogenesis of chronic rhinosinusitis with nasal polyps, Invitrogen mpk 1 antibody (Invitrogen, 44-680G) was used in immunohistochemistry on human samples at 1:50 (fig 6) and in western blot on human samples at 1:1000 (fig 4). Arch Immunol Ther Exp (Warsz) (2014) ncbi
rabbit polyclonal
  • western blot; human; 1:1000
In order to test if extracellular signal-regulated kinase and c-Jun N-terminal kinase are associated with long-term organ damage in SLE patients, Invitrogen mpk 1 antibody (BioSource, 44-680G) was used in western blot on human samples at 1:1000. Rheumatology (Oxford) (2014) ncbi
rabbit polyclonal
  • western blot; human; fig 7
In order to alter the C-terminal trafficking domain of P2X7 and examine its function, Invitrogen mpk 1 antibody (Invitrogen, 44680G) was used in western blot on human samples (fig 7). PLoS ONE (2013) ncbi
rabbit polyclonal
  • immunocytochemistry; Caenorhabditis elegans; fig 7
In order to identify and characterize the role of TFG-1 in protein secretion and export of cargo from the endoplasmic reticulum, Invitrogen mpk 1 antibody (Invitrogen, 44680G) was used in immunocytochemistry on Caenorhabditis elegans samples (fig 7). Nat Cell Biol (2011) ncbi
rabbit polyclonal
  • western blot; human; fig 3
In order to investigate the roles of EGFR and beta1 integrin in ErbB2-driven anchorage independence of tumor cells, Invitrogen mpk 1 antibody (Invitrogen, 44-680G) was used in western blot on human samples (fig 3). J Biol Chem (2011) ncbi
rabbit polyclonal
  • immunohistochemistry; human; 0.5 ug/ul; fig 1
In order to develop an in vitro model for experimental studies of cancer cell invasion, Invitrogen mpk 1 antibody (Biosource, 44-680G) was used in immunohistochemistry on human samples at 0.5 ug/ul (fig 1). Eur J Oral Sci (2010) ncbi
rabbit polyclonal
  • immunocytochemistry; rat; 1:50; fig 3
  • western blot; rat; fig 3
In order to investigate the potential neuroprotective effects of extranuclear estrogen receptors in the brain following cerebral ischemia, Invitrogen mpk 1 antibody (Biosource, 44-680G) was used in immunocytochemistry on rat samples at 1:50 (fig 3) and in western blot on rat samples (fig 3). PLoS ONE (2010) ncbi
rabbit polyclonal
  • western blot; human; 1:1000; fig 1
In order to examine how PDK1 affects MAPK and PI3K signaling in tumor cells, Invitrogen mpk 1 antibody (Invitrogen, 44680G) was used in western blot on human samples at 1:1000 (fig 1). Mol Cancer Res (2010) ncbi
rabbit polyclonal
In order to assess the prognostic value of activated phosphorylated ERK1 and ERK2 and COX-2 at the invasive front and in central/superficial parts of oral squamous cell carcinomas, Invitrogen mpk 1 antibody (BioSource, 44-680G) was used . J Oral Pathol Med (2008) ncbi
rabbit polyclonal
In order to develop an assay to measure temporal, site-specific phosphorylation of key members of the EGFR pathway in A431 cells stimulated with epidermal growth factor, Invitrogen mpk 1 antibody (Invitrogen, 44-680G) was used . Anal Biochem (2008) ncbi
rabbit polyclonal
In order to study the role of laminins during osteogenic differentiation of human mesenchymal stem cells, Invitrogen mpk 1 antibody (Biosource, 44-680) was used . Exp Cell Res (2008) ncbi
rabbit polyclonal
In order to report that FAK is an important mediator of laminin-5-induced osteogenic differentiation of human mesenchymal stem cells, Invitrogen mpk 1 antibody (Biosource, 44-680G) was used . J Cell Biochem (2007) ncbi
rabbit polyclonal
In order to report that epidermal growth factor treatment induced Erk1/2 phosphorylation in rat suprachiasmatic nucleus cells, Invitrogen mpk 1 antibody (Biosources, 44-680G) was used . Brain Res (2006) ncbi
rabbit polyclonal
In order to assess the contribution of CCL2/CCR2 signaling to systemic sclerosis, Invitrogen mpk 1 antibody (BioSource, 44-680G) was used . Arthritis Rheum (2005) ncbi
Articles Reviewed
  1. Roversi F, Pericole F, Machado Neto J, da Silva Santos Duarte A, Longhini A, Corrocher F, et al. Hematopoietic cell kinase (HCK) is a potential therapeutic target for dysplastic and leukemic cells due to integration of erythropoietin/PI3K pathway and regulation of erythropoiesis: HCK in erythropoietin/PI3K pathway. Biochim Biophys Acta Mol Basis Dis. 2017;1863:450-461 pubmed publisher
  2. Caporali S, Alvino E, Lacal P, Levati L, Giurato G, Memoli D, et al. Targeting the PI3K/AKT/mTOR pathway overcomes the stimulating effect of dabrafenib on the invasive behavior of melanoma cells with acquired resistance to the BRAF inhibitor. Int J Oncol. 2016;49:1164-74 pubmed publisher
  3. Köchl R, Thelen F, Vanes L, Brazão T, Fountain K, Xie J, et al. WNK1 kinase balances T cell adhesion versus migration in vivo. Nat Immunol. 2016;17:1075-83 pubmed publisher
  4. Kabe Y, Nakane T, Koike I, Yamamoto T, Sugiura Y, Harada E, et al. Haem-dependent dimerization of PGRMC1/Sigma-2 receptor facilitates cancer proliferation and chemoresistance. Nat Commun. 2016;7:11030 pubmed publisher
  5. Wang J, Goetsch L, Tucker L, Zhang Q, Gonzalez A, Vaidya K, et al. Anti-c-Met monoclonal antibody ABT-700 breaks oncogene addiction in tumors with MET amplification. BMC Cancer. 2016;16:105 pubmed publisher
  6. Fan S, Numata Y, Numata M. Endosomal Na+/H+ exchanger NHE5 influences MET recycling and cell migration. Mol Biol Cell. 2016;27:702-15 pubmed publisher
  7. Shih M, Pan K, Cherng J. Possible Mechanisms of Di(2-ethylhexyl) Phthalate-Induced MMP-2 and MMP-9 Expression in A7r5 Rat Vascular Smooth Muscle Cells. Int J Mol Sci. 2015;16:28800-11 pubmed publisher
  8. Quintero Barceinas R, García Regalado A, Aréchaga Ocampo E, Villegas Sepúlveda N, González De la Rosa C. All-Trans Retinoic Acid Induces Proliferation, Survival, and Migration in A549 Lung Cancer Cells by Activating the ERK Signaling Pathway through a Transcription-Independent Mechanism. Biomed Res Int. 2015;2015:404368 pubmed publisher
  9. Salas E, Roy S, Marsh T, Rubin B, Debnath J. Oxidative pentose phosphate pathway inhibition is a key determinant of antimalarial induced cancer cell death. Oncogene. 2016;35:2913-22 pubmed publisher
  10. Graziani G, Artuso S, De Luca A, Muzi A, Rotili D, Scimeca M, et al. A new water soluble MAPK activator exerts antitumor activity in melanoma cells resistant to the BRAF inhibitor vemurafenib. Biochem Pharmacol. 2015;95:16-27 pubmed publisher
  11. Cheng Z, Liu F, Zhu S, Tian H, Wang L, Wang Y. A rapid and convenient method for fluorescence analysis of in vitro cultivated metacestode vesicles from Echinococcus multilocularis. PLoS ONE. 2015;10:e0118215 pubmed publisher
  12. Murrow L, Malhotra R, Debnath J. ATG12-ATG3 interacts with Alix to promote basal autophagic flux and late endosome function. Nat Cell Biol. 2015;17:300-10 pubmed publisher
  13. Cheng Y, Chen P, Chiang H, Suen C, Hwang M, Lin T, et al. Candidate tumor suppressor B-cell translocation gene 3 impedes neoplastic progression by suppression of AKT. Cell Death Dis. 2015;6:e1584 pubmed publisher
  14. Han P, Zhou X, Chang N, Xiao C, Yan S, Ren H, et al. Hydrogen peroxide primes heart regeneration with a derepression mechanism. Cell Res. 2014;24:1091-107 pubmed publisher
  15. Linke R, Pries R, Könnecke M, Bruchhage K, Böscke R, Gebhard M, et al. The MEK1/2-ERK1/2 pathway is activated in chronic rhinosinusitis with nasal polyps. Arch Immunol Ther Exp (Warsz). 2014;62:217-29 pubmed publisher
  16. Bloch O, Amit Vazina M, Yona E, Molad Y, Rapoport M. Increased ERK and JNK activation and decreased ERK/JNK ratio are associated with long-term organ damage in patients with systemic lupus erythematosus. Rheumatology (Oxford). 2014;53:1034-42 pubmed
  17. Wickert L, Blanchette J, Waldschmidt N, Bertics P, Denu J, Denlinger L, et al. The C-terminus of human nucleotide receptor P2X7 is critical for receptor oligomerization and N-linked glycosylation. PLoS ONE. 2013;8:e63789 pubmed publisher
  18. Witte K, Schuh A, Hegermann J, Sarkeshik A, Mayers J, Schwarze K, et al. TFG-1 function in protein secretion and oncogenesis. Nat Cell Biol. 2011;13:550-8 pubmed publisher
  19. Grassian A, Schafer Z, Brugge J. ErbB2 stabilizes epidermal growth factor receptor (EGFR) expression via Erk and Sprouty2 in extracellular matrix-detached cells. J Biol Chem. 2011;286:79-90 pubmed publisher
  20. Brusevold I, Husvik C, Schreurs O, Schenck K, Bryne M, Søland T. Induction of invasion in an organotypic oral cancer model by CoCl2, a hypoxia mimetic. Eur J Oral Sci. 2010;118:168-76 pubmed publisher
  21. Yang L, Zhang Q, Zhou C, Yang F, Zhang Y, Wang R, et al. Extranuclear estrogen receptors mediate the neuroprotective effects of estrogen in the rat hippocampus. PLoS ONE. 2010;5:e9851 pubmed publisher
  22. Lu Z, Cox Hipkin M, Windsor W, Boyapati A. 3-phosphoinositide-dependent protein kinase-1 regulates proliferation and survival of cancer cells with an activated mitogen-activated protein kinase pathway. Mol Cancer Res. 2010;8:421-32 pubmed publisher
  23. Søland T, Husvik C, Koppang H, Boysen M, Sandvik L, Clausen O, et al. A study of phosphorylated ERK1/2 and COX-2 in early stage (T1-T2) oral squamous cell carcinomas. J Oral Pathol Med. 2008;37:535-42 pubmed publisher
  24. Rauh Adelmann C, Moskow J, Graham J, Yen L, Boucher J, Murphy C, et al. Quantitative measurement of epidermal growth factor receptor-mitogen-activated protein kinase signal transduction using a nine-plex, peptide-based immunoassay. Anal Biochem. 2008;375:255-64 pubmed publisher
  25. Klees R, Salasznyk R, Ward D, Crone D, Williams W, Harris M, et al. Dissection of the osteogenic effects of laminin-332 utilizing specific LG domains: LG3 induces osteogenic differentiation, but not mineralization. Exp Cell Res. 2008;314:763-73 pubmed publisher
  26. Salasznyk R, Klees R, Boskey A, Plopper G. Activation of FAK is necessary for the osteogenic differentiation of human mesenchymal stem cells on laminin-5. J Cell Biochem. 2007;100:499-514 pubmed
  27. Hao H, Schwaber J. Epidermal growth factor receptor induced Erk phosphorylation in the suprachiasmatic nucleus. Brain Res. 2006;1088:45-8 pubmed
  28. Carulli M, Ong V, Ponticos M, Shiwen X, Abraham D, Black C, et al. Chemokine receptor CCR2 expression by systemic sclerosis fibroblasts: evidence for autocrine regulation of myofibroblast differentiation. Arthritis Rheum. 2005;52:3772-82 pubmed