This is a Validated Antibody Database (VAD) review about Caenorhabd.. atp-2, based on 38 published articles (read how Labome selects the articles), using atp-2 antibody in all methods. It is aimed to help Labome visitors find the most suited atp-2 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
atp-2 synonym: ATP synthase subunit beta, mitochondrial

Invitrogen
mouse monoclonal (3D5AB1)
  • western blot; human; 1:2000; loading ...; fig 1b
Invitrogen atp-2 antibody (Life Technologies, A21351) was used in western blot on human samples at 1:2000 (fig 1b). Stem Cells (2017) ncbi
mouse monoclonal (3D5AB1)
  • western blot; rat; loading ...; fig 2a
In order to investigate the mechanisms by which benzo[a]pyrene-induced metabolic reprogramming occur, Invitrogen atp-2 antibody (Life Technologies, A-21351) was used in western blot on rat samples (fig 2a). Sci Rep (2017) ncbi
mouse monoclonal (3D5AB1)
  • immunocytochemistry; rat; 1:500; loading ...
In order to explore how the relationship between OPA1 and BNIP3 impacts dominant optic atrophy pathogenesis, Invitrogen atp-2 antibody (ThermoFisher, A21351) was used in immunocytochemistry on rat samples at 1:500. J Neurochem (2017) ncbi
mouse monoclonal (3D5AB1)
  • western blot; human; loading ...
In order to show direct interference of aggregation-prone Abeta peptides with mitochondrial protein biogenesis, Invitrogen atp-2 antibody (Thermo Fisher, A21351) was used in western blot on human samples . Mol Biol Cell (2016) ncbi
mouse monoclonal (3D5AB1)
  • western blot; human
In order to study the assembly process of human mitochondrial ATP synthase, Invitrogen atp-2 antibody (Molecular Probes, A21351) was used in western blot on human samples . FEBS Lett (2015) ncbi
mouse monoclonal (3D5AB1)
  • western blot; human; 1:1000
In order to examine palmitoyl protein thioesterase 1, Invitrogen atp-2 antibody (Molecular Probes/Life Technologies, A21351) was used in western blot on human samples at 1:1000. Data Brief (2015) ncbi
mouse monoclonal (3D5AB1)
  • western blot; human; 1:1000
In order to identify substrates of human PPT1 using neuronal cells, Invitrogen atp-2 antibody (Molecular Probes/Life Technologies Europe BV, A21351) was used in western blot on human samples at 1:1000. J Proteomics (2015) ncbi
mouse monoclonal (3D5AB1)
  • flow cytometry; human
  • immunocytochemistry; human
In order to examine the effect of apoA-I in the proliferation and the angiogenic capacity of early hEPC, Invitrogen atp-2 antibody (Invitrogen, A21351) was used in flow cytometry on human samples and in immunocytochemistry on human samples . Microvasc Res (2015) ncbi
mouse monoclonal (3D5AB1)
  • western blot; fruit fly; fig 3
In order to identify the ATP synthase beta subunit as a mosquito-cell-expressed chikungunya virus-binding protein, Invitrogen atp-2 antibody (Molecular Probes, A21351) was used in western blot on fruit fly samples (fig 3). Arch Virol (2014) ncbi
mouse monoclonal (3D5AB1)
  • western blot; mouse
In order to test if constitutive activation of SIRT1 in skeletal muscle prevents high fat diet-induced muscle insulin resistance, Invitrogen atp-2 antibody (Life Technologies, A21351) was used in western blot on mouse samples . Am J Physiol Endocrinol Metab (2014) ncbi
mouse monoclonal (3D5AB1)
  • western blot; fruit fly; 1:1500; fig 5s
In order to elucidate the mechanisms by which complex I dysfunction contribute to mitochondrial disease, Invitrogen atp-2 antibody (Invitrogen, A21351) was used in western blot on fruit fly samples at 1:1500 (fig 5s). Dis Model Mech (2014) ncbi
mouse monoclonal (3D5AB1)
  • western blot; fruit fly; 1:2000
In order to investigate how PINK1 is degraded, Invitrogen atp-2 antibody (Molecular Probes, A21351) was used in western blot on fruit fly samples at 1:2000. PLoS Genet (2014) ncbi
mouse monoclonal (3D5AB1)
  • immunocytochemistry; human; fig 1, 5
In order to investigate MLQ as a regulator of mitochondrial ATP synthesis, Invitrogen atp-2 antibody (Molecular Probes, A21351) was used in immunocytochemistry on human samples (fig 1, 5). Genes Cells (2014) ncbi
mouse monoclonal (3D5AB1)
  • western blot; mouse; fig 3
In order to characterize a mouse strain in which IF1 gene was destroyed, Invitrogen atp-2 antibody (Molecular Probes, A21351) was used in western blot on mouse samples (fig 3). Biosci Rep (2013) ncbi
mouse monoclonal (3D5AB1)
  • western blot; human; 1:10000
In order to test if the N-terminus of Bcl-xL contains a mitochondrial targeting signal, Invitrogen atp-2 antibody (Invitrogen, 3D5) was used in western blot on human samples at 1:10000. Mitochondrion (2013) ncbi
mouse monoclonal (3D5AB1)
  • western blot; mouse; fig 5
In order to examine the interactome of Huperzine A, Invitrogen atp-2 antibody (Invitrogen, A21351) was used in western blot on mouse samples (fig 5). PLoS ONE (2012) ncbi
mouse monoclonal (3D5AB1)
  • western blot; human; 1:4000; fig 2
In order to study the interactions between the extracellular PEDF and tumor cell surface ATP synthase, Invitrogen atp-2 antibody (Invitrogen, A21351) was used in western blot on human samples at 1:4000 (fig 2). Int J Oncol (2012) ncbi
mouse monoclonal (3D5AB1)
  • western blot; human; fig 1
In order to study energy metabolism in IF1 knockdown cells, Invitrogen atp-2 antibody (Molecular Probes, A21351) was used in western blot on human samples (fig 1). J Biol Chem (2012) ncbi
mouse monoclonal (3D5AB1)
  • western blot; fruit fly; fig 7
In order to investigate metabolic changes in a Drosophila model of human mitochondrial encephalomyopathy, Invitrogen atp-2 antibody (Invitrogen, A21351) was used in western blot on fruit fly samples (fig 7). PLoS ONE (2011) ncbi
mouse monoclonal (3D5AB1)
  • western blot; Caenorhabditis elegans; fig 2
In order to characterize rad-8 mutants, Invitrogen atp-2 antibody (Invitrogen, A21351) was used in western blot on Caenorhabditis elegans samples (fig 2). Genes Cells (2011) ncbi
mouse monoclonal (3D5AB1)
  • western blot; human; 1:2500; fig 6
In order to determine the enzymatic function of FAHD1, Invitrogen atp-2 antibody (Molecular Probes, A21351) was used in western blot on human samples at 1:2500 (fig 6). J Biol Chem (2011) ncbi
mouse monoclonal (3D5AB1)
  • western blot; mouse; fig 3
In order to examine the effect of PGC-1alpha-related coactivator on the metabolic profile of C2C12 myotubes, Invitrogen atp-2 antibody (Molecular Probes, A21351) was used in western blot on mouse samples (fig 3). Am J Physiol Regul Integr Comp Physiol (2011) ncbi
mouse monoclonal (3D5AB1)
  • western blot; mouse; fig s1
In order to study the effects of microbiome-derived butyrate on the energy metabolism of colonocytes, Invitrogen atp-2 antibody (Invitrogen, A-21351) was used in western blot on mouse samples (fig s1). Cell Metab (2011) ncbi
mouse monoclonal (3D5AB1)
  • western blot; human
In order to investigate the contribution of diabetes-associated protein in insulin-sensitive tissue to ATP synthesis, Invitrogen atp-2 antibody (Molecular Probes, A21351) was used in western blot on human samples . J Biol Chem (2011) ncbi
mouse monoclonal (3D5AB1)
  • western blot; human; fig 8
In order to characterize Rab20, a hypoxia-induced gene, Invitrogen atp-2 antibody (Molecular Probes, A21351) was used in western blot on human samples (fig 8). Biochim Biophys Acta (2011) ncbi
mouse monoclonal (3D5AB1)
  • western blot; human; 1:3000; fig 3
In order to determine the proteome of the ischemic human brain, Invitrogen atp-2 antibody (Invitrogen, A21351) was used in western blot on human samples at 1:3000 (fig 3). J Neuropathol Exp Neurol (2010) ncbi
mouse monoclonal (3D5AB1)
  • western blot; human; fig 4
In order to establish an assay for measuring mitochondrial ATP synthesis in cultured mammalian cells, Invitrogen atp-2 antibody (Molecular Probes, A21351) was used in western blot on human samples (fig 4). Biochem Biophys Res Commun (2010) ncbi
mouse monoclonal (3D5AB1)
  • western blot; mouse; fig 1
In order to study the effects of osmotic changes on the regulation of mitochondrial metabolism and biogenesis in C2C12 myotubes, Invitrogen atp-2 antibody (Molecular Probes, A21351) was used in western blot on mouse samples (fig 1). Am J Physiol Cell Physiol (2010) ncbi
mouse monoclonal (3D5AB1)
  • western blot; mouse; fig 3
In order to identify doxorubicin-induced alterations in adult mouse cardiomyocytes, Invitrogen atp-2 antibody (Invitrogen, A21351) was used in western blot on mouse samples (fig 3). Cell Signal (2010) ncbi
mouse monoclonal (3D5AB1)
  • immunohistochemistry - frozen section; human; 2 ug/ml; fig 19.2.1
  • immunohistochemistry - paraffin section; human; 2 ug/ml; fig 19.2.2
  • immunocytochemistry; human; 2 ug/ml; fig 19.2.3
In order to review methods to study oxidative phosphorylation, Invitrogen atp-2 antibody (Invitrogen, A21351) was used in immunohistochemistry - frozen section on human samples at 2 ug/ml (fig 19.2.1), in immunohistochemistry - paraffin section on human samples at 2 ug/ml (fig 19.2.2) and in immunocytochemistry on human samples at 2 ug/ml (fig 19.2.3). Curr Protoc Hum Genet (2009) ncbi
mouse monoclonal (3D5AB1)
  • immunohistochemistry - paraffin section; rat; 1:200
In order to observe and characterize mitochondria in the rat adrenal gland, Invitrogen atp-2 antibody (Molecular Probes, A-21351) was used in immunohistochemistry - paraffin section on rat samples at 1:200. Acta Histochem (2011) ncbi
mouse monoclonal (3D5AB1)
  • western blot; human; fig 3
In order to describe the signaling pathway engaged by Bz-423 in a Burkitt lymphoma cell line, Invitrogen atp-2 antibody (Invitrogen, A21351) was used in western blot on human samples (fig 3). Biochem Pharmacol (2009) ncbi
mouse monoclonal (3D5AB1)
  • immunocytochemistry; African green monkey; 0.5-4 ug/ml; fig 2
In order to show that commercially available standard fluorescent probes are efficient photoswitches, Invitrogen atp-2 antibody (Invitrogen, A21351) was used in immunocytochemistry on African green monkey samples at 0.5-4 ug/ml (fig 2). J Struct Biol (2008) ncbi
mouse monoclonal (3D5AB1)
  • western blot; mouse
In order to identify the signaling pathway activated by Bz-423 in mouse embryonic fibroblasts, Invitrogen atp-2 antibody (Invitrogen, A21351) was used in western blot on mouse samples . Free Radic Biol Med (2008) ncbi
mouse monoclonal (3D5AB1)
  • western blot; human; 1:5000; fig 5
In order to examine the subproteome of mitochondria isolated from human donor retinal pigment epithelium graded with the Minnesota Grading System, Invitrogen atp-2 antibody (Molecular Probes, A21351) was used in western blot on human samples at 1:5000 (fig 5). Invest Ophthalmol Vis Sci (2008) ncbi
mouse monoclonal (3D5AB1)
  • immunocytochemistry; rat; fig 10
In order to characterize a new water soluble mounting medium called 2,2'-thiodiethanol, that is used for high resolution optical microscopy, Invitrogen atp-2 antibody (MolecularProbes, noca) was used in immunocytochemistry on rat samples (fig 10). Microsc Res Tech (2007) ncbi
mouse monoclonal (3D5AB1)
  • western blot; human
In order to investigate how oxidative phosphorylation contributes to the coordination between nuclear- and mitochondria-encoded mitochondrial proteins, Invitrogen atp-2 antibody (Molecular Probes, A-21351) was used in western blot on human samples . Biochim Biophys Acta (2006) ncbi
mouse monoclonal (3D5AB1)
  • western blot; human; fig 2
In order to study operative pathways in early stages of human colon cancer, Invitrogen atp-2 antibody (Molecular Probes, A-21351) was used in western blot on human samples (fig 2). Am J Physiol Gastrointest Liver Physiol (2006) ncbi
Articles Reviewed
  1. Wanet A, Caruso M, Domelevo Entfellner J, Najar M, Fattaccioli A, Demazy C, et al. The Transcription Factor 7-Like 2-Peroxisome Proliferator-Activated Receptor Gamma Coactivator-1 Alpha Axis Connects Mitochondrial Biogenesis and Metabolic Shift with Stem Cell Commitment to Hepatic Differentiation. Stem Cells. 2017;35:2184-2197 pubmed publisher
  2. Hardonnière K, Fernier M, Gallais I, Mograbi B, Podechard N, Le Ferrec E, et al. Role for the ATPase inhibitory factor 1 in the environmental carcinogen-induced Warburg phenotype. Sci Rep. 2017;7:195 pubmed publisher
  3. Moulis M, Millet A, Daloyau M, Miquel M, Ronsin B, Wissinger B, et al. OPA1 haploinsufficiency induces a BNIP3-dependent decrease in mitophagy in neurons: relevance to Dominant Optic Atrophy. J Neurochem. 2017;140:485-494 pubmed publisher
  4. Cenini G, Rüb C, Bruderek M, Voos W. Amyloid ?-peptides interfere with mitochondrial preprotein import competence by a coaggregation process. Mol Biol Cell. 2016;27:3257-3272 pubmed
  5. Fujikawa M, Sugawara K, Tanabe T, Yoshida M. Assembly of human mitochondrial ATP synthase through two separate intermediates, F1-c-ring and b-e-g complex. FEBS Lett. 2015;589:2707-12 pubmed publisher
  6. Scifo E, Szwajda A, Soliymani R, Pezzini F, Bianchi M, Dapkunas A, et al. Quantitative analysis of PPT1 interactome in human neuroblastoma cells. Data Brief. 2015;4:207-16 pubmed publisher
  7. Scifo E, Szwajda A, Soliymani R, Pezzini F, Bianchi M, Dapkunas A, et al. Proteomic analysis of the palmitoyl protein thioesterase 1 interactome in SH-SY5Y human neuroblastoma cells. J Proteomics. 2015;123:42-53 pubmed publisher
  8. González Pecchi V, Valdés S, Pons V, Honorato P, Martinez L, Lamperti L, et al. Apolipoprotein A-I enhances proliferation of human endothelial progenitor cells and promotes angiogenesis through the cell surface ATP synthase. Microvasc Res. 2015;98:9-15 pubmed publisher
  9. Fongsaran C, Jirakanwisal K, Kuadkitkan A, Wikan N, Wintachai P, Thepparit C, et al. Involvement of ATP synthase β subunit in chikungunya virus entry into insect cells. Arch Virol. 2014;159:3353-64 pubmed publisher
  10. White A, Philp A, Fridolfsson H, Schilling J, Murphy A, Hamilton D, et al. High-fat diet-induced impairment of skeletal muscle insulin sensitivity is not prevented by SIRT1 overexpression. Am J Physiol Endocrinol Metab. 2014;307:E764-72 pubmed publisher
  11. Burman J, Itsara L, Kayser E, Suthammarak W, Wang A, Kaeberlein M, et al. A Drosophila model of mitochondrial disease caused by a complex I mutation that uncouples proton pumping from electron transfer. Dis Model Mech. 2014;7:1165-74 pubmed publisher
  12. Thomas R, Andrews L, Burman J, Lin W, Pallanck L. PINK1-Parkin pathway activity is regulated by degradation of PINK1 in the mitochondrial matrix. PLoS Genet. 2014;10:e1004279 pubmed publisher
  13. Fujikawa M, Ohsakaya S, Sugawara K, Yoshida M. Population of ATP synthase molecules in mitochondria is limited by available 6.8-kDa proteolipid protein (MLQ). Genes Cells. 2014;19:153-60 pubmed publisher
  14. Nakamura J, Fujikawa M, Yoshida M. IF1, a natural inhibitor of mitochondrial ATP synthase, is not essential for the normal growth and breeding of mice. Biosci Rep. 2013;33: pubmed publisher
  15. McNally M, Soane L, Roelofs B, Hartman A, Hardwick J. The N-terminal helix of Bcl-xL targets mitochondria. Mitochondrion. 2013;13:119-24 pubmed publisher
  16. Guo W, Liu S, Peng J, Wei X, Sun Y, Qiu Y, et al. Examining the interactome of huperzine A by magnetic biopanning. PLoS ONE. 2012;7:e37098 pubmed publisher
  17. Deshpande M, Notari L, Subramanian P, Notario V, Becerra S. Inhibition of tumor cell surface ATP synthesis by pigment epithelium-derived factor: implications for antitumor activity. Int J Oncol. 2012;41:219-27 pubmed publisher
  18. Fujikawa M, Imamura H, Nakamura J, Yoshida M. Assessing actual contribution of IF1, inhibitor of mitochondrial FoF1, to ATP homeostasis, cell growth, mitochondrial morphology, and cell viability. J Biol Chem. 2012;287:18781-7 pubmed publisher
  19. Celotto A, Chiu W, Van Voorhies W, Palladino M. Modes of metabolic compensation during mitochondrial disease using the Drosophila model of ATP6 dysfunction. PLoS ONE. 2011;6:e25823 pubmed publisher
  20. Fujii M, Yasuda K, Hartman P, Ayusawa D, Ishii N. A mutation in a mitochondrial dehydrogenase/reductase gene causes an increased sensitivity to oxidative stress and mitochondrial defects in the nematode Caenorhabditis elegans. Genes Cells. 2011;16:1022-34 pubmed publisher
  21. Pircher H, Straganz G, Ehehalt D, Morrow G, Tanguay R, Jansen Durr P. Identification of human fumarylacetoacetate hydrolase domain-containing protein 1 (FAHD1) as a novel mitochondrial acylpyruvase. J Biol Chem. 2011;286:36500-8 pubmed publisher
  22. Philp A, Belew M, Evans A, Pham D, Sivia I, Chen A, et al. The PGC-1?-related coactivator promotes mitochondrial and myogenic adaptations in C2C12 myotubes. Am J Physiol Regul Integr Comp Physiol. 2011;301:R864-72 pubmed publisher
  23. Donohoe D, Garge N, Zhang X, Sun W, O Connell T, Bunger M, et al. The microbiome and butyrate regulate energy metabolism and autophagy in the mammalian colon. Cell Metab. 2011;13:517-26 pubmed publisher
  24. Ohsakaya S, Fujikawa M, Hisabori T, Yoshida M. Knockdown of DAPIT (diabetes-associated protein in insulin-sensitive tissue) results in loss of ATP synthase in mitochondria. J Biol Chem. 2011;286:20292-6 pubmed publisher
  25. Hackenbeck T, Huber R, Schietke R, Knaup K, Monti J, Wu X, et al. The GTPase RAB20 is a HIF target with mitochondrial localization mediating apoptosis in hypoxia. Biochim Biophys Acta. 2011;1813:1-13 pubmed publisher
  26. Cuadrado E, Rosell A, Colome N, Hernandez Guillamon M, García Berrocoso T, Ribo M, et al. The proteome of human brain after ischemic stroke. J Neuropathol Exp Neurol. 2010;69:1105-15 pubmed publisher
  27. Fujikawa M, Yoshida M. A sensitive, simple assay of mitochondrial ATP synthesis of cultured mammalian cells suitable for high-throughput analysis. Biochem Biophys Res Commun. 2010;401:538-43 pubmed publisher
  28. Philp A, Perez Schindler J, Green C, Hamilton D, Baar K. Pyruvate suppresses PGC1alpha expression and substrate utilization despite increased respiratory chain content in C2C12 myotubes. Am J Physiol Cell Physiol. 2010;299:C240-50 pubmed publisher
  29. Venkatesan B, Prabhu S, Venkatachalam K, Mummidi S, Valente A, Clark R, et al. WNT1-inducible signaling pathway protein-1 activates diverse cell survival pathways and blocks doxorubicin-induced cardiomyocyte death. Cell Signal. 2010;22:809-20 pubmed publisher
  30. De Paepe B, De Bleecker J, Van Coster R. Histochemical methods for the diagnosis of mitochondrial diseases. Curr Protoc Hum Genet. 2009;Chapter 19:Unit19.2 pubmed publisher
  31. Ogawa K, Harada K, Endo Y, Sagawa S, Inoue M. Heterogeneous levels of oxidative phosphorylation enzymes in rat adrenal glands. Acta Histochem. 2011;113:24-31 pubmed publisher
  32. Blatt N, Boitano A, Lyssiotis C, Opipari A, Glick G. Bz-423 superoxide signals B cell apoptosis via Mcl-1, Bak, and Bax. Biochem Pharmacol. 2009;78:966-73 pubmed publisher
  33. van de Linde S, Sauer M, Heilemann M. Subdiffraction-resolution fluorescence imaging of proteins in the mitochondrial inner membrane with photoswitchable fluorophores. J Struct Biol. 2008;164:250-4 pubmed publisher
  34. Blatt N, Boitano A, Lyssiotis C, Opipari A, Glick G. Bz-423 superoxide signals apoptosis via selective activation of JNK, Bak, and Bax. Free Radic Biol Med. 2008;45:1232-42 pubmed publisher
  35. Nordgaard C, Karunadharma P, Feng X, Olsen T, Ferrington D. Mitochondrial proteomics of the retinal pigment epithelium at progressive stages of age-related macular degeneration. Invest Ophthalmol Vis Sci. 2008;49:2848-55 pubmed publisher
  36. Staudt T, Lang M, Medda R, Engelhardt J, Hell S. 2,2'-thiodiethanol: a new water soluble mounting medium for high resolution optical microscopy. Microsc Res Tech. 2007;70:1-9 pubmed
  37. Mazzanti R, Giulivi C. Coordination of nuclear- and mitochondrial-DNA encoded proteins in cancer and normal colon tissues. Biochim Biophys Acta. 2006;1757:618-23 pubmed
  38. Mazzanti R, Solazzo M, Fantappiè O, Elfering S, Pantaleo P, Bechi P, et al. Differential expression proteomics of human colon cancer. Am J Physiol Gastrointest Liver Physiol. 2006;290:G1329-38 pubmed