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Alomone Labs Ranolazine inhibits NaV1.4 channels heterologously expressed inXenopusoocytes cells. - A. Time course of the skeletal NaV1.4 current inhibition by 100 200 and 500 MRanolazine(#R-110). Currents were elicited by application of voltage ramps from a holding potential of -100 mV to +30 mV (100 msec). B. Superimposed example traces of current responses before and during perfusion of 100 200 and 500 M Ranolazine as indicated.
Western blot analysis of rat (lanes 1 and 3) and mouse (lanes 2 and 4)kidney membranes: - 12.Anti-GPR4 (extracellular) Antibody (#AGR-041) (1:200).34. Anti-GPR4 (extracellular) Antibody preincubated with the negative control antigen.
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