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Alomone Labs Ergtoxin-1 inhibits the current of KV11.1 (hErg) channels expressed inXenopusoocytes. - A. Representative time course ofKV11.1 current inhibition by 50 nM Ergtoxin-1(#STE-450) as indicated (green). B. Superimposed traces of KV11.1 current after application of control solution (black) and of 50 nM Ergtoxin-1 (green) taken from the recording in A. Membrane potential was held at -100 mV. Current was elicited every 10 sec by a 200 ms voltage step to +40 mV followed by a 200 ms step to -40 mV (as shown below).
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