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company name :
ichorbio
product type :
antibody
product name :
Anti-TNF alpha In Vivo Antibody - Ultra Low Endotoxin (TN3-19.12 ) [ICH1136UL] ichorbio
catalog :
ICH1136UL
quantity :
5 mg
price :
312 GBP
clonality :
monoclonal
host :
hamsters
conjugate :
nonconjugated
clone name :
TN3-19.12
reactivity :
mouse
application :
western blot, immunoprecipitation
more info or order :
product information
Product Type :
Ultra Low Endotoxin
ichorbio Cat Number :
ICH1136UL
Page Title :
Anti-TNF alpha In Vivo Antibody - Ultra Low Endotoxin (TN3-19.12 ) [ICH1136UL] ichorbio
Page Heading :
Anti-TNF alpha In Vivo Antibody - Ultra Low Endotoxin (TN3-19.12 ) [ICH1136UL]
Page Heading :
Bulk anti-TNF alpha In Vivo Antibody - Ultra Low Endotoxin (TN3-19.12 )
Product Benefits :
ichorbio's anti-TNF alpha In Vivo Antibody - Ultra Low Endotoxin (TN3-19.12 ) is manufactured in a cGMP compliant, ISO Quality Standard 9001:2015 facility. This means that ichorbio's ultra low-endoxin antibodies have the lowest endotoxin in the industry at less than 0.75 EU/mg. The purity of ichorbio's ultra low endotoxin antibodies are unsurpassed at >98% and they are all pathogen tested and third-party certified by IDEXX BioReseach of meet the lowest mycoplasma specification and free of any viral pathogens of concern. ichorbio offers Amazon vouchers or donations to the NC3Rs for reviews of this product: click here for more information. ichorbio: the best antibodies for in vivo research.
Target :
TNF alpha
Clone :
TN3-19.12
Size1 :
5 mg
Academic Price1 :
312 GBP
Size2 :
25mg
Academic Price2 :
832
Size3 :
50mg
Academic Price3 :
1352
Size4 :
100mg
Academic Price4 :
2080
Isotype :
Armenian Hamster IgG
Other names :
Cachectin, TNFa, Tumor necrosis factor ligand superfamily member 2, Tnfsf2
UniProt :
P06804
Host :
Armenian Hamster
Species Reactivity :
Mouse
Specificity :
Anti-TNF alpha In Vivo Antibody - Ultra Low Endotoxin (TN3-19.12 ) recognizes Mouse TNFa
Purification method :
This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Antigen Distribution :
Activated monocytes, neutrophils, macrophages, T cells, B cells, NK cells, LAK cells
Background :
The tumor necrosis factor (TNF-alpha) is a multifaceted polypeptide cytokine known as a mediator of inflammation and immunity. It may mediate some of the significant changes in cellular homeostasis which accompany the invasion of the mammalian host by viruses, bacteria, and parasites. TNF-alpha is an acute phase protein which initiates a cascade of cytokines and increases vascular permeability, thereby recruiting macrophage and neutrophils to a site of infection. TNF-alpha secreted by the macrophage causes blood clotting which serves to contain the infection. TNF-alpha has been detected in synovial fluid of patients with rheumatoid arthritis. Clone TN3-19.12 antibody can neutralize the bioactivity of natural or recombinant TNF-alpha
Immunogen :
Recombinant mouse TNFalpha
Concentration :
≥ 2.0 mg/ml
Formulation :
0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added. BSA and Azide free.
Purity :
>98% by SDS-PAGE and HPLC
Endotoxin :
≤ 0.75 EU/mg as determined by the LAL method
Aggregation :
Aggregation level ≤ 1%
IMPACT Pathogen Test :
We use the IMPACT test generated by IDEXX Laboratories to guarantee our Ultra Low Endotoxin antibodies are pathogen free. Our hamster antibodies are tested for:
Mycoplasma spp
Mycoplasma pulmonis
Pneumonia virus of mice
Kilham's rat virus
Toolan's H1 virus
Hamster parvovirus
Lymphocytic choriomeningitis
Minute virus of mice
Theiler's murine encephalomyelitis virus
Sendai virus
Reovirus 3
Hantaan virus
Storage :
anti-TNF alpha In Vivo Antibody - Ultra Low Endotoxin (TN3-19.12 ) is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Applications :
Immunoprecipitation, Western Blot
Application Notes :
Each investigator should determine their own optimal working dilution for specific applications.
Isotype Control :
Armenian Hamster IgG Isotype Control for In Vivo - Ultra Low Endotoxin [PIP] (ICH2251UL)
Related Antibody :
Anti-TNF alpha In Vivo Antibody - Low Endotoxin [TN3-19.12] (ICH1136)
Antibodies against the same target :
Anti-TNF alpha In Vivo Antibody - Low Endotoxin [MP6-XT22] (ICH1127)
Use :
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Pricing Note :
Contact for industrial pricing
more info or order :
company information

ichorbio
Grove Business Park
Downsview Road
Wantage OX12 9FF
Downsview Road
Wantage OX12 9FF
hello@ichor.bio
https://www.ichor.bioheadquarters: UK
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